Fiona Watt
British scientist
Fiona Watt's AcademicInfluence.com Rankings
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Biology
Fiona Watt's Degrees
- Bachelors Biology University of Oxford
- PhD Molecular Biology Imperial College London
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(Suggest an Edit or Addition)According to Wikipedia, Fiona Watt, is a British scientist who is internationally known for her contributions to the field of stem cell biology. In the 1980s, when the field was in its infancy, she highlighted key characteristics of stem cells and their environment that laid the foundation for much present day research. She is currently director of the Centre for Stem Cells & Regenerative Medicine at King's College London, and Executive Chair of the Medical Research Council , the first woman to lead the MRC since its foundation in 1913. On 13 July 2021 she was appointed as the new Director of the European Molecular Biology Organization .
Fiona Watt's Published Works
Published Works
- Out of Eden: stem cells and their niches. (2000) (1796)
- A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1376)
- The Human Cell Atlas (2017) (1285)
- Regulation of development and differentiation by the extracellular matrix. (1993) (1267)
- Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression (1993) (1120)
- Autophagy mediates the mitotic senescence transition. (2009) (962)
- Distinct fibroblast lineages determine dermal architecture in skin development and repair (2013) (829)
- Stem cell patterning and fate in human epidermis (1995) (816)
- Role of the extracellular matrix in regulating stem cell fate (2013) (712)
- Role of integrins in regulating epidermal adhesion, growth and differentiation (2002) (663)
- Lineage Tracing (2012) (550)
- Stem cells: the generation and maintenance of cellular diversity. (1989) (520)
- Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis (2009) (485)
- Modulating the stem cell niche for tissue regeneration (2014) (481)
- Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters (2000) (462)
- Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis (2003) (434)
- Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronectin binding precedes α 5 β 1 integrin loss from the cell surface (1990) (431)
- Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation (2017) (425)
- Fibronectin inhibits the terminal differentiation of human keratinocytes (1989) (424)
- Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes (2013) (424)
- Epidermal stem cells: markers, patterning and the control of stem cell fate. (1998) (413)
- Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions (2010) (410)
- Common genetic variation drives molecular heterogeneity in human iPSCs (2017) (397)
- Cell shape controls terminal differentiation of human epidermal keratinocytes. (1988) (392)
- Epithelial stem cells, wound healing and cancer (2012) (386)
- The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. (1999) (383)
- Lrig1 controls intestinal stem cell homeostasis by negative regulation of ErbB signalling (2012) (378)
- Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours (2004) (359)
- c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny (2001) (357)
- Contribution of stem cells and differentiated cells to epidermal tumours (2003) (346)
- Hair follicle dermal papilla cells at a glance (2011) (330)
- c-Myc promotes differentiation of human epidermal stem cells. (1997) (326)
- Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence (2006) (312)
- Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis (1995) (311)
- The EGF Receptor Provides an Essential Survival Signal for SOS-Dependent Skin Tumor Development (2000) (308)
- Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. (2002) (302)
- Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis (2009) (299)
- Stratification and terminal differentiation of cultured epidermal cells (1982) (296)
- Calcium-induced reorganization of desmosomal components in cultured human keratinocytes (1984) (296)
- Cell-extracellular matrix interactions in normal and diseased skin. (2011) (294)
- Involucrin synthesis is correlated with cell size in human epidermal cultures (1981) (287)
- A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. (2002) (282)
- Stem Cell Depletion Through Epidermal Deletion of Rac1 (2005) (270)
- Terminal differentiation of epidermal keratinocytes. (1989) (270)
- The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche (2011) (268)
- Involucrin and other markers of keratinocyte terminal differentiation. (1983) (266)
- Understanding fibroblast heterogeneity in the skin. (2015) (265)
- Epidermal Notch signalling: differentiation, cancer and adhesion (2008) (265)
- Stem cell fate and patterning in mammalian epidermis. (2001) (255)
- Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. (1992) (255)
- beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. (1999) (252)
- Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. (2005) (251)
- Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations (2018) (244)
- The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregulated in Tumors (2006) (243)
- Fibroblast heterogeneity: implications for human disease (2018) (241)
- Jagged 1 is a β-catenin target gene required for ectopic hair follicle formation in adult epidermis (2006) (239)
- Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro. (1999) (234)
- Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways (2003) (233)
- Stem cells are dispensable for lung homeostasis but restore airways after injury (2009) (228)
- The plakin family: versatile organizers of cytoskeletal architecture. (1997) (221)
- The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells (2006) (219)
- Periplakin, a Novel Component of Cornified Envelopes and Desmosomes That Belongs to the Plakin Family and Forms Complexes with Envoplakin (1997) (217)
- Integrin expression during human epidermal development in vivo and in vitro. (1991) (215)
- Designer skin: lineage commitment in postnatal epidermis. (2002) (204)
- Defining dermal adipose tissue (2014) (203)
- Epidermal stem cells: an update. (2006) (201)
- The skin and its diseases : a subject collection from Cold Spring Harbor perspectives in medicine (2014) (201)
- Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment (2003) (200)
- Towards gene therapy for haemophilia B using primary human keratinocytes (1993) (194)
- Selective migration of terminally differentiating cells from the basal layer of cultured human epidermis (1984) (188)
- New roles for integrins in squamous-cell carcinoma (2006) (186)
- The extracellular matrix and cell shape (1986) (186)
- Epithelial Cell Differentiation Pathways in the Human Prostate: Identification of Intermediate Phenotypes by Keratin Expression (2001) (184)
- Sic transit gloria: farewell to the epidermal transit amplifying cell? (2007) (182)
- Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells. (1996) (182)
- Indian hedgehog and β-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalian epidermis (2003) (181)
- Proliferative Heterogeneity in the Human Prostate: Evidence for Epithelial Stem Cells (2000) (180)
- Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes (1991) (177)
- Epidermal stem cell diversity and quiescence (2009) (175)
- The therapeutic potential of stem cells (2010) (174)
- DNA amplification is rare in normal human cells. (1990) (173)
- Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin (1996) (172)
- Skin Cell Heterogeneity in Development, Wound Healing, and Cancer (2018) (172)
- Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules. (1991) (171)
- Letter: Islet-cell hyperplasia and sudden infant death. (1976) (170)
- Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. (1996) (170)
- Epidermal stem cells are retained in vivo throughout skin aging (2008) (170)
- Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. (1988) (168)
- A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. (2001) (167)
- Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis (2010) (165)
- Developmental cell programs are co-opted in inflammatory skin disease (2021) (161)
- The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate (2011) (160)
- Mammalian skin cell biology: At the interface between laboratory and clinic (2014) (160)
- beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms. (2000) (159)
- Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. (1997) (158)
- Regulation of keratinocyte terminal differentiation by integrin-extracellular matrix interactions. (1993) (157)
- Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation (1995) (152)
- MYC in mammalian epidermis: how can an oncogene stimulate differentiation? (2008) (151)
- Defining Adult Stem Cells by Function, not by Phenotype. (2018) (151)
- Human sebaceous tumors harbor inactivating mutations in LEF1 (2006) (150)
- Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium (2000) (150)
- Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium (1993) (150)
- Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs (2005) (150)
- Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3 (2008) (149)
- Antinuclear Autoantibodies and Lupus Nephritis in Transgenic Mice Expressing Interferon γ in the Epidermis (1997) (148)
- Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis (2003) (148)
- Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier (2007) (142)
- Diverse epigenetic strategies interact to control epidermal differentiation (2012) (142)
- Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes (1999) (141)
- Measurement of the rate of epidermal terminal differentiation: expression of involucrin by S-phase keratinocytes in culture and in psoriatic plaques. (1987) (139)
- The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis (2008) (138)
- Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia (1982) (135)
- Stem cell heterogeneity and plasticity in epithelia. (2015) (132)
- Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surface. (1990) (131)
- Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin (2011) (129)
- Changes in the expression of αv integrins in oral squamous cell carcinomas (1997) (125)
- Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors (2014) (123)
- Neuroendocrine differentiation in human gastric carcinoma (1998) (123)
- Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c‐Myc and β‐Catenin (2008) (123)
- Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1 (2006) (120)
- Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of the oral cavity (1998) (120)
- Keratinocyte Differentiation Is Regulated by the Rho and ROCK Signaling Pathway (2003) (117)
- Biochemical specificity of Xenopus notochord. (1985) (115)
- The stem cell compartment in human interfollicular epidermis. (2002) (113)
- Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties (2017) (113)
- Influence of cytochalasin D-induced changes in cell shape on proteoglycan synthesis by cultured articular chondrocytes. (1988) (111)
- Diverse mechanisms for endogenous regeneration and repair in mammalian organs (2018) (109)
- Innate sensing of microbial products promotes wound-induced skin cancer (2015) (105)
- Human skin aging is associated with reduced expression of the stem cell markers beta1 integrin and MCSP. (2010) (104)
- Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes. (1996) (102)
- Transcriptional and post-translational regulation of beta 1 integrin expression during keratinocyte terminal differentiation. (1992) (102)
- Epidermal label-retaining cells: background and recent applications. (2004) (101)
- Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation (2007) (100)
- Expression and function of the keratinocyte integrins. (1993) (100)
- Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis (2004) (97)
- Subpopulations of chondrocytes from different zones of pig articular cartilage. Isolation, growth and proteoglycan synthesis in culture. (1990) (96)
- Markers of epidermal stem cell subpopulations in adult mammalian skin. (2014) (96)
- Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale (2010) (95)
- Subcellular Distribution of Envoplakin and Periplakin Insights into Their Role as Precursors of the Epidermal Cornified Envelope (2000) (94)
- Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions. (2004) (92)
- Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing (2016) (90)
- Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt (2004) (89)
- Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages (2016) (88)
- Interaction of periplakin and envoplakin with intermediate filaments (2002) (88)
- Mechanisms, Hallmarks, and Implications of Stem Cell Quiescence (2019) (88)
- Differentiated structural components of the keratinocyte. (1982) (87)
- Fibroblast state switching orchestrates dermal maturation and wound healing (2017) (87)
- The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages that Are Differentially Regulated by Wnt, Edaradd, and Lrig1 (2013) (86)
- Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells (2013) (86)
- CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion. (1995) (84)
- Suprabasal α6β4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFβ signalling (2003) (84)
- The Epidermal Stem Cell Compartment: Variation in Expression Levels of E–Cadherin and Catenins Within the Basal Layer of Human Epidermis (1997) (84)
- Gene Targeting of Envoplakin, a Cytoskeletal Linker Protein and Precursor of the Epidermal Cornified Envelope (2001) (83)
- Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes. (1987) (82)
- Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. (2008) (79)
- Erratum: Extracellular-matrix tethering regulates stem-cell fate (Nature Materials (2012) 11 (642-649)) (2012) (77)
- Changes in expression of members of the fos and jun families and myc network during terminal differentiation of human keratinocytes. (1995) (77)
- A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control (2003) (75)
- Type XVII collagen coordinates proliferation in the interfollicular epidermis (2017) (75)
- Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing. (2013) (75)
- Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate (2010) (75)
- A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells (2017) (74)
- Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. (2007) (74)
- Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. (1996) (74)
- Prolonged expression of differentiated phenotype by chondrocytes cultured at low density on a composite substrate of collagen and agarose that restricts cell spreading. (1988) (73)
- Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane (2004) (72)
- Characterisation of eight monoclonal antibodies to involucrin. (1992) (71)
- Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo (2011) (70)
- Cell culture models of differentiation (1991) (70)
- Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. (2008) (69)
- β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis (2016) (68)
- Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer. (2010) (68)
- Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas. (1993) (68)
- Loss of α6 and β4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas (1993) (67)
- Calcium-induced changes in distribution and solubility of cadherins, integrins and their associated cytoplasmic proteins in human keratinocytes. (1995) (66)
- Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiation (1999) (66)
- Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 (2019) (65)
- Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer. (2008) (65)
- Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes. (1993) (65)
- β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial–mesenchymal transition (2012) (64)
- p19ARF‐independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes (2001) (64)
- A stem cell gene expression profile of human squamous cell carcinomas (2008) (64)
- Unexpected Hedgehog-Wnt interactions in epithelial differentiation. (2004) (62)
- Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication. (2005) (62)
- c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis (2013) (61)
- Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture (2007) (60)
- Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes (2000) (60)
- Paraneoplastic pemphigus sera react strongly with multiple epitopes on the various regions of envoplakin and periplakin, except for the c-terminal homologous domain of periplakin. (2001) (59)
- Decreased expression of fibronectin and the alpha 5 beta 1 integrin during terminal differentiation of human keratinocytes. (1991) (58)
- Changes in the expression of alpha v integrins in oral squamous cell carcinomas. (1997) (58)
- Functional down-regulation of alpha 5 beta 1 integrin in keratinocytes is reversible but commitment to terminal differentiation is not. (1993) (58)
- Dermal fibroblast-derived growth factors restore the ability of beta(1) integrin-deficient embryonal stem cells to differentiate into keratinocytes. (2001) (57)
- An unusual strain of human keratinocytes which do not stratify or undergo terminal differentiation in culture (1988) (57)
- Altered expression of CD44 isoforms in squamous‐cell carcinomas and cell lines derived from them (1996) (56)
- Sox2 modulates the function of two distinct cell lineages in mouse skin☆ (2013) (56)
- Delta regulates keratinocyte spreading and motility independently of differentiation (2001) (55)
- The Human Cell Atlas White Paper (2018) (55)
- Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility (2014) (54)
- Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth (2017) (54)
- FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. (2012) (53)
- Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation (2011) (53)
- Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex (1998) (53)
- Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells (2016) (52)
- Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells (2013) (52)
- Role of LIM kinases in normal and psoriatic human epidermis. (2006) (51)
- Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity (2016) (50)
- Influence of β1 Integrins on Epidermal Squamous Cell Carcinoma Formation in a Transgenic Mouse Model α3β1, but not α2β1, Suppresses Malignant Conversion (2001) (50)
- Regulation of Interleukin-1α Expression by Integrins and Epidermal Growth Factor Receptor in Keratinocytes from a Mouse Model of Inflammatory Skin Disease* (2003) (48)
- BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions (2014) (48)
- Influence of Cell Shape and Adhesiveness on Stratification and Terminal Differentiation of Human Keratinocytes in Culture (1987) (48)
- Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Cell Carcinoma Metastasis (2014) (48)
- Expression of Notch pathway genes in mammalian epidermis and modulation by β‐Catenin (2007) (48)
- Lung endocrine cell markers, peptides, and amines (1993) (48)
- Changes in the abundance and distribution of actin and associated proteins during terminal differentiation of human epidermal keratinocytes. (1991) (47)
- Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen (2014) (47)
- Mimicking the topography of the epidermal-dermal interface with elastomer substrates. (2016) (46)
- Production of scatter factor by ndk, a strain of epithelial cells, and inhibition of scatter factor activity by suramin. (1991) (46)
- Efficient Differentiation of Embryonic Stem Cells into Mesodermal Precursors by BMP, Retinoic Acid and Notch Signalling (2012) (46)
- Restoration of alpha v beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth. (1996) (46)
- The adaptive immune response to cardiac injury—the true roadblock to effective regenerative therapies? (2017) (45)
- Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling. (2003) (45)
- A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis (2017) (45)
- The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells (2015) (44)
- A high-content platform to characterise human induced pluripotent stem cell lines (2016) (44)
- A model for in vitro studies of epidermal homeostasis: proliferation and involucrin synthesis by cultured human keratinocytes during recovery after stripping off the suprabasal layers. (1988) (44)
- PA‐FABP, a novel marker of human epidermal transit amplifying cells revealed by 2D protein gel electrophoresis and cDNA array hybridisation (2000) (44)
- The epidermal keratinocyte. (1988) (44)
- Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex. (1998) (44)
- Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differentiation (2008) (43)
- Epidermal stem cells as targets for gene transfer. (2000) (43)
- Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation (2010) (43)
- Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis (2012) (42)
- The α2 and α5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes (2000) (41)
- Generative adversarial networks uncover epidermal regulators and predict single cell perturbations (2018) (41)
- An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. (2009) (41)
- Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 (2010) (40)
- LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development (2013) (40)
- Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocytes in culture. (1991) (40)
- An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis (2018) (40)
- Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation (2012) (40)
- Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns. (2013) (39)
- Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion. (2001) (39)
- Changes in the distribution of actin-associated proteins during epidermal wound healing. (1993) (39)
- Integrin expression by human epidermal keratinocytes can be modulated by interferon-γ, transforming growth factor-β, tumor necrosis factor-α, and culture on a dermal equivalent (1995) (39)
- (More) women in science (2018) (38)
- Onset of expression of peanut lectin-binding glycoproteins is correlated with stratification of keratinocytes during human epidermal development in vivo and in vitro. (1989) (37)
- Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic and physical maps of the TOC region on 17q25. (1999) (37)
- The distribution of actin cables and microtubules in hybrids between malignant and non-malignant cells, and in tumours derived from them. (1978) (37)
- Two strains of human keratinocytes transfected with HPV16 DNA: comparison with the normal parental cells. (1991) (37)
- KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules (2009) (37)
- Keratinocyte cultures: an experimental model for studying how proliferation and terminal differentiation are co-ordinated in the epidermis. (1988) (36)
- Necl2 regulates epidermal adhesion and wound repair (2009) (36)
- Translational control of stem cell function (2021) (36)
- Epidermal stem cells in culture (1988) (36)
- Generative adversarial networks simulate gene expression and predict perturbations in single cells (2018) (36)
- Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid. (1985) (35)
- Map clusters of diseases to tackle multimorbidity (2020) (35)
- Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis (2020) (34)
- Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation (2010) (34)
- A central role for alpha beta T cells in the pathogenesis of murine lupus. (1999) (33)
- Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure (2016) (32)
- HAN11 binds mDia1 and controls GLI1 transcriptional activity. (2006) (32)
- Signaling via b 1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro ( keratinocyte y adhesiveness ) (1999) (32)
- PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation (2009) (31)
- High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning (2019) (31)
- Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation (2015) (31)
- Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes (2020) (31)
- Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation (2016) (30)
- Heterogeneous expression of keratin, involucrin, and extracellular matrix among subpopulations of a poorly differentiated human cervical carcinoma: possible relationships to patterns of invasion. (1989) (30)
- Seven actionable strategies for advancing women in science, engineering, and medicine. (2015) (30)
- Mitogens induce calcium transients in both dividing and terminally differentiating keratinocytes. (1991) (30)
- Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors (2019) (29)
- Homeostasis, regeneration and tumour formation in the mammalian epidermis. (2018) (29)
- The vitamin D receptor is required for mouse hair cycle progression but not for maintenance of the epidermal stem cell compartment. (2008) (29)
- Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. (2019) (29)
- What is the point of large-scale collections of human iPS cells? (2013) (29)
- Advancing research (2014) (29)
- Spatial constraints govern competition of mutant clones in human epidermis (2017) (29)
- Hair follicle epidermal stem cells define a niche for tactile sensation (2018) (28)
- Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis (2020) (27)
- Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness (2019) (27)
- Patterns of junctional communication in skin: studies on cultured keratinocytes. (1987) (27)
- Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis. (2016) (26)
- The peanut lectin-binding glycoproteins of human epidermal keratinocytes. (1988) (25)
- Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity (2010) (25)
- Chromosomal localisation of the human envoplakin gene (EVPL) to the region of the tylosis oesophageal cancer gene (TOCG) on 17q25. (1996) (24)
- Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes (1987) (24)
- The alpha2 and alpha5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes. (2000) (24)
- Role of integrins in mouse eyelid development: studies in normal embryos and embryos in which there is a failure of eyelid fusion (1998) (23)
- Engineered Microenvironments to Direct Epidermal Stem Cell Behavior at Single-Cell Resolution. (2016) (23)
- Proliferation and terminal differentiation of human epidermal keratinocytes in culture. (1988) (23)
- Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse (2014) (23)
- Expression of 01 , 03 , 04 , and 05 Integrins by HumanEpidermal Keratinocytes and Non-Differentiating Keratinocytes (2002) (23)
- The eLife approach to peer review (2013) (22)
- Immunomodulatory role of Keratin 76 in oral and gastric cancer (2018) (22)
- ISLET-CELL HYPERPLASIA AND SUDDEN INFANT DEATH (1976) (21)
- Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology (2020) (21)
- AVERTED SUDDEN NEONATAL DEATH DUE TO PANCREATIC NESIDIOBLASTOSIS (1978) (21)
- Structure and Regulation of the Envoplakin Gene* (2000) (21)
- Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility (2016) (21)
- Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin (2012) (20)
- Integrin expression and function in HPV 16-immortalised human keratinocytes in the presence or absence of v-Ha-ras. Comparison with cervical intraepithelial neoplasia. (1994) (20)
- Calcium-induced intercellular adhesion of keratinocytes does not involve accumulation of beta 1 integrins at cell-cell contacts and does not involve changes in the levels or phosphorylation of catenins. (1998) (19)
- Common genetic variation drives molecular heterogeneity in human iPSCs (2016) (19)
- Repeal and Replace: Adipocyte Regeneration in Wound Repair. (2017) (19)
- Preparation of fowl testes as recipient organs to germ-line chimeras by means of gamma-radiation (2003) (18)
- Microtubule-organizing centres in mammalian cells in culture. (1980) (18)
- Epidermal deletion of Rac1 causes stem cell depletion, irrespective of whether deletion occurs during embryogenesis or adulthood. (2007) (18)
- Epidermal Cadm1 Expression Promotes Autoimmune Alopecia via Enhanced T Cell Adhesion and Cytotoxicity (2012) (17)
- Downregulation of Keratin 76 Expression during Oral Carcinogenesis of Human, Hamster and Mouse (2013) (17)
- Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture (2019) (17)
- A Novel Automated High-Content Analysis Workflow Capturing Cell Population Dynamics from Induced Pluripotent Stem Cell Live Imaging Data (2016) (17)
- Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro (2018) (16)
- Adhesion of human epidermal keratinocytes to laminin. (1994) (16)
- Human epidermal stem cell differentiation is modulated by specific lipid subspecies (2020) (16)
- Suprabasal α5β1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFβ signaling or inducing spindle cell tumors (2005) (16)
- Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells (2017) (16)
- KazrinA is required for axial elongation and epidermal integrity in Xenopus tropicalis (2008) (16)
- Mutant Lef1 controls Gata6 in sebaceous gland development and cancer (2019) (15)
- Pentapeptide inhibitor of epidermal mitosis: production and responsiveness in cultures of normal, transformed and neoplastic human keratinocytes. (1989) (15)
- Integrin expression by human epidermal keratinocytes can be modulated by interferon-gamma, transforming growth factor-beta, tumor necrosis factor-alpha, and culture on a dermal equivalent. (1995) (15)
- Functional down-regulation of 5 1 integrin in keratinocytes is reversible but commitment to terminal differentiation is not (15)
- Cultivation and Retroviral Infection of Human Epidermal Keratinocytes (2006) (15)
- High-throughput stem-cell niches (2011) (14)
- Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair (2021) (14)
- Identification of Novel Keratinocyte Differentiation Modulating Compounds by High-Throughput Screening (2006) (14)
- Microtubule-organizing centres in binucleate cells and homosynkaryons. (1980) (14)
- Micro-scaled topographies direct differentiation of human epidermal stem cells (2019) (13)
- Clinically-relevant vulnerabilities of deep machine learning systems for skin cancer diagnosis. (2020) (13)
- Sequence variation in the I-like domain of the beta1 integrin subunit in human oral squamous cell carcinomas. (2004) (13)
- Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pathways. (2016) (12)
- A blueprint for translational regenerative medicine (2020) (12)
- Transfection of beta 4 integrin subunit into a neoplastic keratinocyte line fails to restore terminal differentiation capacity or influence proliferation. (1996) (12)
- Suprabasal alpha 5 beta1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFbeta signaling or inducing spindle cell tumors. (2005) (12)
- Erratum: What is the point of large-scale collections of human induced pluripotent stem cells? (2013) (11)
- Studies with cultured human epidermal keratinocytes: Potential relevance to corneal wound healing (1994) (11)
- Rac1 Deletion Causes Thymic Atrophy (2011) (10)
- Characterisation of the peanut lectin-binding glycoproteins of human epidermal keratinocytes. (1990) (10)
- Loss of alpha 6 and beta 4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas. (1993) (10)
- Changes in cell-surface carbohydrate during terminal differentiation of human epidermal keratinocytes. (1992) (10)
- On science publishing in general and JCS in particular (2000) (10)
- Author response: The Human Cell Atlas (2017) (10)
- Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression (2020) (9)
- Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation (2018) (9)
- Changes in type I keratin expression associated with HPV16 transformation of human epidermal keratinocytes. (1992) (9)
- Bench to bedside: Current advances in regenerative medicine. (2018) (9)
- Understanding allergy and cancer risk: what are the barriers? (2015) (9)
- β1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum (2000) (9)
- Poised cell circuits in human skin are activated in disease (2020) (8)
- Employing core regulatory circuits to define cell identity (2021) (8)
- Fibrotic enzymes modulate wound‐induced skin tumorigenesis (2021) (8)
- A tumor-associated (cid:2) 1 integrin mutation that abrogates epithelial differentiation control (2003) (8)
- An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function (2022) (8)
- Launching eLife, Part 1 (2012) (8)
- Dynamic Culture Substrates That Mimic the Topography of the Epidermal–Dermal Junction (2019) (8)
- Electronimmunocytochemistry of gut hormones (1978) (8)
- A genome-wide screen identifies YAP / WBP 2 interplay conferring growth advantage on human epidermal stem cells (2017) (7)
- Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility. (2015) (7)
- Heterogeneity of the D1 Cell (1981) (7)
- Functional genomics and the future of iPSCs in disease modeling (2022) (7)
- Women in cell biology: getting to the top (2006) (7)
- Non-profit publishing: open access and the end of copyright transfer (2004) (6)
- NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis (2019) (6)
- A year in the life of eLife (2013) (6)
- Cell Therapy for Lung Disease (2010) (6)
- Identification of an 80kD protein associated with the alpha 3 beta 1 integrin as a proteolytic fragment of the alpha 3 subunit: studies with human keratinocytes. (1995) (6)
- FRMD 4 A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis (2012) (6)
- Localization of Peptides in the Lung (1991) (6)
- A Central Role for αβ T Cells in the Pathogenesis of Murine Lupus (1999) (6)
- Mammalian Epidermis: A Compendium of Lipid Functionality (2022) (5)
- Gene activating glasses (2020) (5)
- Women in cell biology: how personal lives shape careers (2006) (5)
- Looking to Europe (2008) (5)
- Exons 5–15 of Kazrin Are Dispensable for Murine Epidermal Morphogenesis and Homeostasis (2012) (4)
- Mentorship in Science: Response to AlShebli et al., Nature Communications 2020 (2021) (4)
- Common genetic variation drives molecular heterogeneity in human iPSCs (vol 546, pg 370, 2017) (2017) (4)
- Launching eLife, Part 2 (2012) (4)
- Cell differentiation: Focus on epithelia (2003) (4)
- The 5′ noncoding region of the mouse involucrin gene: comparison with the human gene and genes encoding other cornified envelope precursors (1995) (3)
- Best Paper Award 2013 (2014) (3)
- MYC in mammalian epidermis: how can an oncogene stimulate differentiation? (Erratum) (2008) (3)
- Joyce Taylor-Papadimitriou (2003) (3)
- Myosin 10 is involved in murine pigmentation (2018) (3)
- The role of keratins in modulating carcinogenesis via communication with cells of the immune system (2019) (3)
- Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression (2020) (3)
- Funding: end ‘publish or perish’ for postdocs (2022) (3)
- Anna El'skaya (2005) (3)
- eLife and early career researchers (2013) (3)
- Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage (2021) (3)
- 19 Epidermal Stem Cells (2001) (2)
- Sharyn Endow (2004) (2)
- Editorial overview: From stem cells to specialized cells: signaling and gene regulation in cell differentiation (2001) (2)
- 23 – Human Epidermal Stem Cells (2004) (2)
- High-throughput micro-patterning platform reveals Nodal-dependent dissection of peri-gastrulation-associated versus pre-neurulation associated fate patterning (2018) (2)
- Epithelial diferentiation pathways in the human prostate (2001) (2)
- Angiotensin-Converting Enzyme 2 Expression Is Detectable in Keratinocytes, Cutaneous Appendages, and Blood Vessels by Multiplex RNA In Situ Hybridization (2022) (2)
- 1354 Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations: International Investigative Dermatology (IID) 2018 Meeting Abstract SupplementInternational Investigative Dermatology (IID) 2018 (2018) (2)
- Zena Werb (2004) (2)
- Integrin Special Issue (2009) (2)
- Stem cells: on the front line (2011) (2)
- Stem Cell Manifesto Stem Cells Edited by C. S. Potten Academic Press: London (1997). 512 pp., $105.00 (1999) (2)
- Recognizing the importance of new tools and resources for research (2015) (2)
- The adaptive immune response to cardiac injury—the true roadblock to effective regenerative therapies? (2017) (2)
- Women in cell science (2004) (2)
- Influence of b 1 Integrins on Epidermal Squamous Cell Carcinoma Formation in a Transgenic Mouse Model : a 3 b 1 , but not a 2 b 1 , Suppresses Malignant Conversion 1 (2001) (2)
- ERK basal and pulsatile activity are differentially regulated in mammalian epidermis to control proliferation and exit from the stem cell compartment (2020) (2)
- Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation (2021) (2)
- Differential Expression of Insulin-Like Growth Factor 1 and Wnt Family Member 4 Correlates With Functional Heterogeneity of Human Dermal Fibroblasts (2021) (2)
- Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
- UK funders learn from COVID-19 ‘white-water ride’ (2020) (2)
- The periplakin gene maps to 16p13.3 in human and 16A-B1 in mouse. (1998) (2)
- Decreased expression of fibronectin and the a ^ lh integrin during terminal differentiation of human keratinocytes (2005) (2)
- Adipocytes in Skin Health and Disease (2014) (1)
- 4 THE EXTRACELLULAR MATRIX PROTEIN LAMININ ALPHA 5 REGULATES THE BEHAVIOUR OF HEPATIC PROGENITOR CELLS IN REGENERATING MOUSE LIVER (2013) (1)
- Calcium-induced Reorganization Components in Cultured Human of Desmosomal Keratinocytes (2003) (1)
- UVB induction of p53 protein expression in cultured normal human melanocytes: 262 (1993) (1)
- Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells (2018) (1)
- Identifying the genetic basis of variation in cell behaviour in human iPS cell lines from healthy donors (2018) (1)
- Functional comparison of adult and pluripotent stem cell-derived hepatocytes (2020) (1)
- Topo II alpha reporter mice reveal proliferative regions in the epidermis and small intestine. (2005) (1)
- Epidermal b -catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages (2016) (1)
- Author response: Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility (2014) (1)
- LSC 2012 abstract - LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and preinvasive squamous cell carcinoma development (2012) (1)
- 13 – Cell Shape and Vertebrate Embryogenesis (1989) (1)
- Transgenic Mice Expressing IFN-γ in the Epidermis Are a Model of Inflammatory Skin Disease and Systemic Lupus Erythematosus (2005) (1)
- Subcellular Distribution of Envoplakin and Periplakin (2000) (1)
- Effect of Culture Environment on Terminal Differentiation of Human Epidermal Keratinocytes (1991) (1)
- Control of Involucrin Synthesis During Terminal Differentiation of Human Epidermal Cells in Culture (1983) (1)
- Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation (2021) (1)
- Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism (2022) (1)
- Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer (2022) (1)
- Julia Polak. (2004) (1)
- More about substance P. (1985) (1)
- IMMUNOREACTIVE MOTILINS? (1978) (1)
- Danielle Dhouailly (2004) (1)
- Best Paper Award 2006 (2006) (1)
- Fran Balkwill (2005) (1)
- Mary Osborn (2004) (1)
- Irene Leigh (2005) (1)
- What does it take to recruit and retain senior women faculty? (2013) (1)
- Amparo Cano (2004) (1)
- Emiliana Borrelli (2005) (1)
- Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression (2020) (1)
- A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1)
- Hair follicle stem cells define a niche for tactile sensation via secretion of a specialized ECM (2017) (0)
- Topo IIα reporter mice reveal proliferative regions in the epidermis and small intestine (2005) (0)
- Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration (2013) (0)
- Progenitor Cells in Development and Regeneration of the Hair Follicle The Dermal Papilla : An Instructive Niche for Epithelial Stem and (2014) (0)
- BG04: Exploring the cellular and genetic composition of human basal cell carcinoma at single‐cell and spatial resolutions (2022) (0)
- From Molecules to Skin and Feathers. Current Topics in Developmental Biology, volume 22. The Molecular and Developmental Biology of Keratins. Ed. by Roger H. Sawyer. Academic Press Inc., NY, 1986. 285 pages. Hardcover. $45.00 (1988) (0)
- A Transgenic Mouse Model of Systemic Lupus Erythematosus (2000) (0)
- Epidermal Health and Disease Desmosomes : Regulators of Cellular Signaling and Adhesion in Subject Collection The Skin and Its Diseases Immunology and Skin in Health and Disease (2014) (0)
- CIRM and UKRMP: Different Ways to Invest in Regenerative Medicine. (2016) (0)
- 75: Role of inflammation in epidermal carcinogenesis (2014) (0)
- Protein phosphatase PP1-NIPP1 regulates epidermal homeostasis and the repair capacity of carcinogen-induced DNA damage (2016) (0)
- Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro (2018) (0)
- The Role of the αv Integrin Receptor in Malignant Oral Epithelium (1995) (0)
- 397 The role of Keratins in modulating carcinogenesis via communication with cells of the immune system (2019) (0)
- Abstract IA06: Stem cells in mammalian epidermis (2016) (0)
- Topo IIa reporter mice reveal proliferative regions in the epidermis and small intestine (2005) (0)
- Best Paper Award 2003. (2004) (0)
- The effect of changes in cell shape on proteoglycan synthesis in cultured chondrocytes (1987) (0)
- Dynamic regulation of human epidermal differentiation by adhesive and mechanical forces. (2022) (0)
- Irrigation of squamous cell carcinoma wounds to prevent local recurrence (2012) (0)
- Loss of α6 and β4 integrins and basement cell membrane proteins in oral squamous cell carcinomas (1993) (0)
- 857 Fibroblast heterogeneity in human adult dermis: IGF-1/TGF-β1 signal modification to rejuvenate reticular fibroblasts (2018) (0)
- Transgenic mice expressing IFN-gamma in the epidermis are a model of inflammatory skin disease and systemic lupus erythematosus. (2005) (0)
- Fibroblast Heterogeneity in Healthy and Wounded Skin. (2022) (0)
- New Perspectives on Old Questions Engineered microenvironments to direct epidermal stem cell behaviour at single cell resolution (2016) (0)
- Immunomodulatory role of Keratin 76 in oral and gastric cancer (2018) (0)
- Keynote speakers (2014) (0)
- Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture (2019) (0)
- Protein phosphatase PP1-NIPP1 controls epidermal homeostasis and susceptibility to DMBA-induced skin carcinogenesis (2016) (0)
- 289 Characterization of a Mouse Model of Wound-induced Tumour Formation (2012) (0)
- Reconstructing human Brown Fat developmental trajectory in vitro (2022) (0)
- Deposited in DRO : 11 May 2018 Version of attached (2020) (0)
- Defining the functional role of laminin isoforms in the adult hepatic progenitor cell response (2013) (0)
- Letter in Response to "Stabilization of β-catenin does not increase dermal papilla cell number in the hair follicle". (2016) (0)
- Faculty Opinions recommendation of Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. (2003) (0)
- Glutathione depletion leads to epidermal stem cell differentiation through the PI3K/Akt/FoxO pathway (2011) (0)
- O18. Stem cells in adult mammalian epidermis (2010) (0)
- Understanding Human Epidermal Stem Cells at Single-Cell Resolution (2022) (0)
- S58 Beta-Catenin determines tracheal cell fate and squamous lung cancer progression by modulating intercellular adhesiveness (2011) (0)
- 060 Envoplakin is one of the paraneoplastic pemphigus antigen complex (1997) (0)
- Jcb: Supplemental Material (0)
- A proposal to use gamete cycling in vitro to improve crops and livestock (2013) (0)
- Expression and function of the keratinocyte integrins. (1993) (0)
- in preventing (2006) (0)
- Dexamethasone inhibits MEK1-related epithelial tumours in vivo (2005) (0)
- Correction: Rac1 Deletion Causes Thymic Atrophy (2011) (0)
- 2007 Winners: Adi Dubash Masamitsu Sone (2008) (0)
- A reductionist approach to determine the effect of cell-cell contact on human epidermal stem cell differentiation (2022) (0)
- Survey of Dutch agricultural law. (1962) (0)
- Hydrogen peroxide production by epidermal dual oxidase 1 regulates nociceptive sensory signals (2022) (0)
- Localized EGFL6 regulates the architecture and location of sensory terminals in the hair follicle (2016) (0)
- Progress and challenges in stem cell biology (2023) (0)
- Reply to Chi et al. (2017) (0)
- Agricultural law : report (1958) (0)
- [X-ray semiotics of the morphological and functional changes in chronic bronchitis]. (1985) (0)
- Mutant Lef 1 controls Gata 6 in sebaceous gland development and cancer (2019) (0)
- Immunofluorescence Technology (1983) (0)
- Cloning of the human cyclin L cDNA from lung (2000) (0)
- Book review (2005) (0)
- Individual peptides SUBSTANCE P The undecapeptide substance (0)
- P88 FRMD4A is a potential marker of tumour stem cells in Human Head and Neck Squamous Cell Carcinoma (HNSCC) (2010) (0)
- [Theses for the diagnosis of lung cancer]. (1982) (0)
- Distinct wave patterns of ERK MAPK activation control epidermal proliferation and migration in vivo (2017) (0)
- ERK MAPK activation bursts and propagation in adult and embryonic mouse skin (2017) (0)
- Abstract 2016: Mst2 is required for tumor progression and Yap activity (2014) (0)
- New JCS Editor (2007) (0)
- The reward of great collaborations (2018) (0)
- Hirschsprung's disease and peptidergic innervation (1987) (0)
- Title: Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation Overline: Transplantation Single sentence summary: Mesenchymal stromal cell apoptosis, induced in vivo by recipient (2018) (0)
- Structural policy and size of farms in agriculture. (1960) (0)
- Keratinocyte culture club (1982) (0)
- Monoclonal antibodies at em level (1987) (0)
- Book reviews (2005) (0)
- [The mechanism of thermal effects in paraffin therapy]. (1979) (0)
- Book Review : Letter to the Editor (1967) (0)
- The Humanities (2015) (0)
- Prevention of MEK1-associated tumours in murine epidermis by inhibition of interleukin-1 (2007) (0)
- Consortia - the motion picture (2005) (0)
- Xin Lu (2004) (0)
- Keynote Lectures (2013) (0)
- Faculty Opinions recommendation of EFF-1 is sufficient to initiate and execute tissue-specific cell fusion in C. elegans. (2004) (0)
- Best Paper Award 2002 (2003) (0)
- Cell differentiation The search for the holy grail (1998) (0)
- Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes (2020) (0)
- Severing ties (2007) (0)
- Farewell to JCS (2011) (0)
- Cell biology as the centuries change (2008) (0)
- Best Paper Award 2001 (2002) (0)
- In vitro properties of chondrocytes isolated from different zones of pig articular cartilage (1987) (0)
- Design as performance (2013) (0)
- Jungle: La Jungla (2009) (0)
- Data for Developmental cell programs are co-opted in inflammatory skin disease - filtered, annotated anndata object (2020) (0)
- 2009 Winner: Ravi Desai (2010) (0)
- Daniel Louvard: a profile (2006) (0)
- Within the Basal Layer of Human Epidermis Cadherin and Catenins - The Epidermal Stem Cell Compartment: Variation in Expression Levels of E (2013) (0)
- Janet Heasman (2004) (0)
- End of an era (2004) (0)
- JCS in 2010 – Ringing in the Changes (2010) (0)
- New JCS Editor (2011) (0)
- Envoplakin, a new keratinocyte protein that is a cornified envelope precursor and belongs to the desmoplakin family. (1996) (0)
- Make/Believe: UK Design for Performance 2011 - 2015 (2015) (0)
- Hide and Seek (2005) (0)
- Julia Polak (2004) (0)
- Abstract IA03: Fibroblast heterogeneity in skin tumour stroma (2016) (0)
- Explorer FRMD 4 A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis (2017) (0)
- LYVE-1 + Macrophages Form a Collaborative CCR5-Dependent Perivascular Niche That Influences Chemotherapy Responses in Cancer (2022) (0)
- 581 A genome-wide screen identifies YAP/WBP2/TEAD interplay conferring growth advantage on human epidermal stem cells (2019) (0)
- New JCS Editor (2009) (0)
- Explorer The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages that Are Differentially Regulated by Wnt , Edaradd , and Lrig (2017) (0)
- Elaine Fuchs (2004) (0)
- (More) women in science (2018) (0)
- From The Lancet Love philtres (1990) (0)
- 2010 Winner: Leyla Kocgozlu (2011) (0)
- The Usborne Internet-Linked Children's World Cookbook (2000) (0)
- Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 (2019) (0)
- Monique Aumailley (2005) (0)
- Instructions for use Title Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with ReducedCancer Susceptibility (2019) (0)
- An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis (2018) (0)
- Talila Volk (2005) (0)
- Pop-Up Jungle (2015) (0)
- Stem cell renewal and lineage selection in mammalian epidermis (2008) (0)
- JCS Prize. 2006 winner: Satomi Matsuoka. (2007) (0)
- Best Paper Award 2004 (2005) (0)
- 2006 Winner: Satomi Matsuoka (2007) (0)
- Map clusters of diseases to tackle multimorbidity (2020) (0)
- The Usborne big book of christmas things to make and do (2005) (0)
- Best Paper Award 2005 (2006) (0)
- Previous CHANEL-CERIES. Research Award Winners: (2013) (0)
- Diverse mechanisms for endogenous regeneration and repair in mammalian organs (2018) (0)
- 1351 Investigation of the molecular identity of the junctional zone in human (2018) (0)
- The reward of great collaborations (2018) (0)
- Elizabeth Hay (2004) (0)
- Cell Biology of Tissues and Tumors (2010) (0)
- Faculty Opinions recommendation of A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. (2002) (0)
- JCS online - HighWire Press, free access and non-profit publishing (2001) (0)
- Targetting stem cells in squamous cell carcinoma (2012) (0)
- 2008 Winner: Jennifer Levy (2009) (0)
- ISSCR: Annual ReportLetter from the President (2009) (0)
- 085 Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis (2017) (0)
- Author response: Population-scale proteome variation in human induced pluripotent stem cells (2020) (0)
- Professor Sir Henry Harris (1925-2014). (2015) (0)
- 210 Three-dimensional models of human skin at single-cell resolution in health and disease (2019) (0)
- Adhesion and Cytotoxicity Autoimmune Alopecia via Enhanced T Cell Epidermal Cadm1 Expression Promotes (2011) (0)
- The role of the vitronectin receptor in malignant oral epithelium (1995) (0)
- The αvβ5 Integrin Induces Anoikis in Squamous Cell Carcinoma (SCC) cells by Activating the Intrinsic and Extrinsic Death Pathways and Inhibiting An Akt/PKB Survival Signal (2003) (0)
- 320 Studying interplay between delta-like1 and jagged1 in regulating epidermal stem cell fate decisions at single cell resolution (2023) (0)
- 660 Dermal fibroblast subpopulations as a potential cell therapy for promoting scar-free wound healing and resolving scar formation (2019) (0)
- 272 Understanding cell heterogeneity in the basal layer of human epidermis (2019) (0)
- 554 Dissecting fibroblast heterogeneity in skin cancer (2017) (0)
- Balancing work and life: a conversation with Fiona Watt. Interview by Majlinda Lako and Susan Daher. (2009) (0)
- O48. Tumour stem cells in head and neck squamous cell carcinoma (HNSCC) (2009) (0)
- 589 Loss of GATA6 contributes to acne pathogenesis in human skin (2019) (0)
- The extracellular matrix and cell a cobblestone appearance when cultured (1986) (0)
- 716 Chemical Carcinogenesis in Mice With a Defective Epidermal Barrier – Exploring the Connection Between Skin Barrier and Cancer Susceptibility (2012) (0)
- Gata 6 in sebaceous gland development and cancer (2019) (0)
- Fibronectin-keratinocyte interactions during terminal differentiation (1990) (0)
- Cell-to-cell contact and extracellular matrix. (2004) (0)
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