Florian Holsboer
#60,152
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Swiss chemist
Florian Holsboer's AcademicInfluence.com Rankings
Florian Holsboerchemistry Degrees
Chemistry
#655
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#1115
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Organic Chemistry
#60
World Rank
#89
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Chemistry
Florian Holsboer's Degrees
- PhD Chemistry University of Zurich
- Bachelors Chemistry University of Zurich
Why Is Florian Holsboer Influential?
(Suggest an Edit or Addition)Florian Holsboer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Stress and the brain: from adaptation to disease (2005) (4108)
- The Corticosteroid Receptor Hypothesis of Depression (2000) (2112)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Differential signal transduction by five splice variants of the PACAP receptor (1993) (1208)
- Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions (2012) (1178)
- Dynamic DNA methylation programs persistent adverse effects of early-life stress (2009) (1151)
- A mega-analysis of genome-wide association studies for major depressive disorder (2013) (979)
- Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 (1998) (928)
- Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment (2004) (908)
- Antidepressants and hypothalamic-pituitary-adrenocortical regulation. (1996) (885)
- Neuroprotection against oxidative stress by estrogens: structure-activity relationship. (1997) (770)
- Common genetic variants influence human subcortical brain structures (2015) (731)
- Genome-wide, large-scale production of mutant mice by ENU mutagenesis (2000) (696)
- Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. (2000) (681)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. (1994) (669)
- Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions (2007) (657)
- Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives (1999) (648)
- 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. (1995) (637)
- The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety. (1999) (626)
- Identification of common variants associated with human hippocampal and intracranial volumes (2012) (617)
- Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy. (2001) (607)
- FK506-binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells* (2005) (555)
- Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study (2000) (543)
- Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation (2016) (525)
- Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo (2000) (509)
- Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. (2002) (503)
- Psychoneuroendocrinology (1979) (458)
- Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress (2003) (444)
- Effects of antidepressant treatment on neuroactive steroids in major depression. (1998) (440)
- Genomewide Association for Major Depressive Disorder: A possible role for the presynaptic protein Piccolo (2008) (410)
- Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system? (1995) (402)
- Altered hypothalamic-pituitary-adrenocortical regulation in healthy subjects at high familial risk for affective disorders. (1995) (389)
- Blunted corticotropin and normal cortisol response to human corticotropin-releasing factor in depression. (1984) (366)
- Stress hormone regulation: biological role and translation into therapy. (2010) (366)
- Development of the brain's default mode network from wakefulness to slow wave sleep. (2011) (363)
- Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. a prospective study. (2001) (363)
- Central CRH system in depression and anxiety--evidence from clinical studies with CRH1 receptor antagonists. (2008) (360)
- Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system. (1993) (360)
- The genetic architecture of the human cerebral cortex (2018) (355)
- Dissociated central and peripheral release of vasopressin, but not oxytocin, in response to repeated swim stress: New insights into the secretory capacities of peptidergic neurons (1998) (352)
- Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression (2008) (341)
- Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker? (2007) (341)
- V1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats (1995) (330)
- Corticotropin-releasing hormone receptor subtypes and emotion (1999) (328)
- Cellular Localization of Interleukin 6 mRNA and Interleukin 6 Receptor mRNA in Rat Brain (1993) (320)
- Polymorphisms of the Glucocorticoid Receptor Gene and Major Depression (2006) (319)
- Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour (1998) (315)
- RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia (2007) (314)
- Reduced Anxiety, Conditioned Fear, and Hippocampal Long-Term Potentiation in Transient Receptor Potential Vanilloid Type 1 Receptor-Deficient Mice (2007) (313)
- Plasma Protein Biomarkers for Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections (2010) (309)
- Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression (2005) (305)
- Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls (2008) (303)
- Repeated dexamethasone suppression test during depressive illness. Normalisation of test result compared with clinical improvement. (1982) (300)
- Progesterone receptor-mediated effects of neuroactive steroids (1993) (298)
- The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus (1994) (297)
- A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. (2009) (297)
- Heterodimerization between mineralocorticoid and glucocorticoid receptor: A new principle of glucocorticoid action in the CNS (1994) (294)
- Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. (1993) (293)
- Gene expression and function of interleukin I, interleukin 6 and tumor necrosis factor in the brain (1994) (293)
- Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1 (2011) (291)
- Repetitive transcranial magnetic stimulation increases the release of dopamine in the mesolimbic and mesostriatal system (2002) (288)
- Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. (2001) (288)
- Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks (2009) (280)
- Subtle shifts in the ratio between pro‐ and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate (2000) (280)
- Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways. (2002) (279)
- The combined dexamethasone/CRH test as a potential surrogate marker in depression (2005) (274)
- Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts (2010) (273)
- Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects. (1996) (273)
- PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome (2008) (269)
- The Neurosteroid Tetrahydroprogesterone Attenuates the Endocrine Response to Stress and Exerts Glucocorticoid-like Effects on Vasopressin Gene Transcription in the Rat Hypothalamus (1996) (268)
- Stress responsive neurohormones in depression and anxiety. (2003) (262)
- Alterations in Central Neuropeptide Expression, Release, and Receptor Binding in Rats Bred for High Anxiety: Critical Role of Vasopressin (2004) (261)
- Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety (2005) (260)
- Effects of intravenous corticotropin-releasing hormone upon sleep-related growth hormone surge and sleep EEG in man. (1988) (252)
- Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. (2011) (252)
- Genome-wide association study of major recurrent depression in the U.K. population. (2010) (251)
- SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection (2019) (250)
- Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus (2001) (249)
- Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity. (2009) (247)
- Prediction of medium-term outcome by cortisol response to the combined dexamethasone-CRH test in patients with remitted depression. (1999) (245)
- Age-associated changes of pituitary-adrenocortical hormone regulation in humans: Importance of gender (1994) (244)
- Translocator Protein (18 kD) as Target for Anxiolytics Without Benzodiazepine-Like Side Effects (2009) (242)
- Release of Vasopressin within the Rat Paraventricular Nucleus in Response to Emotional Stress: A Novel Mechanism of Regulating Adrenocorticotropic Hormone Secretion? (1996) (241)
- Novel genetic loci associated with hippocampal volume (2017) (238)
- FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior (2011) (236)
- P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. (2006) (236)
- Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: an in vivo microdialysis study (1995) (233)
- Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats (1995) (231)
- Brain activation and hypothalamic functional connectivity during human non-rapid eye movement sleep: an EEG/fMRI study. (2006) (231)
- The brain mineralocorticoid receptor: greedy for ligand, mysterious in function. (2000) (225)
- Enhanced and Delayed Stress-Induced Alcohol Drinking in Mice Lacking Functional CRH1 Receptors (2002) (219)
- Penetration of Amitriptyline, but Not of Fluoxetine, into Brain is Enhanced in Mice with Blood-Brain Barrier Deficiency Due to Mdr1a P-Glycoprotein Gene Disruption (2000) (219)
- Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. (2013) (219)
- Corticosteroid receptor function is decreased in depressed patients. (1997) (217)
- Effects of growth hormone-releasing hormone and somatostatin on sleep EEG and nocturnal hormone secretion in male controls. (1992) (216)
- Hormonal Response Pattern in the Combined DEX-CRH Test Is Stable over Time in Subjects at High Familial Risk for Affective Disorders (1998) (215)
- The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression (2009) (211)
- Psychological Stress Increases Hippocampal Mineralocorticoid Receptor Levels: Involvement of Corticotropin-Releasing Hormone (2001) (210)
- Cerebrospinal fluid concentrations of corticotropin‐releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: Response to amitriptyline treatment (1998) (209)
- Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. (1997) (207)
- Neural correlates of dream lucidity obtained from contrasting lucid versus non-lucid REM sleep: a combined EEG/fMRI case study. (2012) (206)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression Implications for pathophysiology of DST nonsuppression (1987) (205)
- Penetration of Endogenous Steroid Hormones Corticosterone, Cortisol, Aldosterone and Progesterone into the Brain is Enhanced in Mice Deficient for Both mdr1a and mdr1b P‐Glycoproteins (2002) (205)
- Functional microstates within human REM sleep: first evidence from fMRI of a thalamocortical network specific for phasic REM periods (2007) (203)
- Transcranial magnetic stimulation as a therapeutic tool in psychiatry: what do we know about the neurobiological mechanisms? (2001) (199)
- High Constitutive NF-κB Activity Mediates Resistance to Oxidative Stress in Neuronal Cells (1998) (198)
- Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders (2001) (196)
- Dose-dependent effects of endotoxin on human sleep. (2000) (195)
- Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation (2005) (193)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association (2016) (192)
- Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption (2003) (192)
- Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor. (1993) (189)
- The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress (2012) (189)
- Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain. (1999) (189)
- Persistent neuroendocrine and behavioral effects of a novel, etiologically relevant mouse paradigm for chronic social stress during adolescence (2007) (188)
- Altered Processing of Acoustic Stimuli during Sleep: Reduced Auditory Activation and Visual Deactivation Detected by a Combined fMRI/EEG Study (2002) (188)
- Concentrations of 3α-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery (1999) (188)
- Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD (2010) (187)
- Hypothalamic-pituitary-adrenocortical axis changes in the rat after long-term treatment with the reversible monoamine oxidase-A inhibitor moclobemide. (1994) (183)
- Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder (2006) (183)
- Anxiety: a potential predictor of vulnerability to the initiation of ethanol self-administration in rats (1995) (183)
- Long‐Term Antidepressant Treatment Reduces Behavioural Deficits in Transgenic Mice with Impaired Glucocorticoid Receptor Function (1995) (180)
- Combined dexamethasone/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I (1995) (180)
- Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. (2011) (179)
- Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk (2003) (178)
- Functional MRI during sleep: BOLD signal decreases and their electrophysiological correlates (2004) (177)
- Polymorphisms in GRIK4, HTR2A, and FKBP5 Show Interactive Effects in Predicting Remission to Antidepressant Treatment (2010) (177)
- Behavioral, Physiological, and Neuroendocrine Stress Responses and Differential Sensitivity to Diazepam in Two Wistar Rat Lines Selectively Bred for High- and Low-Anxiety–Related Behavior (1998) (176)
- Long-term behavioral and neuroendocrine alterations following chronic social stress in mice: Implications for stress-related disorders (2008) (176)
- Exacerbation of Apoptosis in the Dentate Gyrus of the Aged Rat by Dexamethasone and the Protective Role of Corticosterone (1996) (176)
- Overweight and Obesity Affect Treatment Response in Major Depression (2007) (174)
- How can we realize the promise of personalized antidepressant medicines? (2008) (174)
- Progesterone induces changes in sleep comparable to those of agonistic GABAA receptor modulators. (1996) (173)
- Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning? (2012) (172)
- Mice selected for high versus low stress reactivity: A new animal model for affective disorders (2008) (172)
- Sleep Spindles and Hippocampal Functional Connectivity in Human NREM Sleep (2011) (171)
- The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia. (1992) (170)
- Long-Term Intracerebroventricular Infusion of Corticotropin-Releasing Hormone Alters Neuroendocrine, Neurochemical, Autonomic, Behavioral, and Cytokine Responses to a Systemic Inflammatory Challenge (1997) (169)
- Depression, comorbidities and the TNF-α system (2008) (168)
- Vasopressin Mediates the Response of the Combined Dexamethasone/CRH Test in Hyper-anxious Rats: Implications for Pathogenesis of Affective Disorders (2002) (167)
- Acute transcranial magnetic stimulation of frontal brain regions selectively modulates the release of vasopressin, biogenic amines and amino acids in the rat brain (2000) (165)
- Neuropeptide S receptor gene — converging evidence for a role in panic disorder (2011) (164)
- Reduction of Hypothalamic Vasopressinergic Hyperdrive Contributes to Clinically Relevant Behavioral and Neuroendocrine Effects of Chronic Paroxetine Treatment in a Psychopathological Rat Model (2003) (163)
- Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. (2008) (162)
- Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders (2004) (160)
- Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats. (1994) (159)
- Combined dexamethasone/corticotropin-releasing hormone test in patients with schizophrenia and in normal controls: II (1995) (159)
- Impaired Repression at a Vasopressin Promoter Polymorphism Underlies Overexpression of Vasopressin in a Rat Model of Trait Anxiety (2004) (158)
- Clinical and Neurobiological Effects of Tianeptine and Paroxetine in Major Depression (2003) (158)
- Soluble interleukin‐6 (IL‐6) receptor augments central effects of IL‐6 in vivo (1995) (158)
- Cortisol Response to a Combined Dexamethasone‐Human Corticotrophin‐Releasing Hormone Challenge in Patients with Depression (1989) (158)
- The anxiolytic effect of the CRH1 receptor antagonist R121919 depends on innate emotionality in rats (2001) (157)
- Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology (2001) (157)
- Low lumbar bone mineral density in patients with major depression. (1994) (156)
- Progesterone-induced changes in sleep in male subjects. (1997) (153)
- Combined administration of human corticotropin-releasing factor and lysine vasopressin induces cortisol escape from dexamethasone suppression in healthy subjects. (1985) (153)
- Sleep EEG and nocturnal secretion of cortisol and growth hormone in male patients with endogenous depression before treatment and after recovery. (1989) (152)
- Glucocorticoids and depression. (1999) (150)
- Pharmacological and Nonpharmacological Factors Influencing Hypothalamic–Pituitary–Adrenocortical Axis Reactivity in Acutely Depressed Psychiatric In-patients, Measured by the Dex-CRH Test (2003) (150)
- Effects of transgenic overproduction of CRH on anxiety‐like behaviour (2002) (149)
- Genetic architecture of subcortical brain structures in 38,851 individuals (2019) (148)
- Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling (2011) (147)
- Heterodimerization between mineralocorticoid and glucocorticoid receptors increases the functional diversity of corticosteroid action. (1996) (147)
- Forebrain CRF1 Modulates Early-Life Stress-Programmed Cognitive Deficits (2011) (147)
- Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression (2013) (145)
- TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies (2011) (145)
- Behavioural performance in three substrains of mouse strain 129 (1997) (144)
- Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism (2006) (144)
- Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. (1994) (144)
- "Anxietas tibiarum". Depression and anxiety disorders in patients with restless legs syndrome. (2005) (144)
- Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropin‐releasing hormone receptor‐dependent mechanism (2002) (144)
- The female sex hormone oestrogen as a neuroprotectant. (1999) (141)
- Increased sleep pressure reduces resting state functional connectivity (2010) (140)
- IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations (2008) (140)
- Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice (2008) (139)
- Induction of NF-κB Activity during Haloperidol-Induced Oxidative Toxicity in Clonal Hippocampal Cells: Suppression of NF-κB and Neuroprotection by Antioxidants (1998) (139)
- In quest of identifying vulnerability markers for psychiatric disorders by all-night polysomnography. (1995) (138)
- Dreamed Movement Elicits Activation in the Sensorimotor Cortex (2011) (137)
- Persistent Cognitive Impairment in Depression: The Role of Psychopathology and Altered Hypothalamic-Pituitary-Adrenocortical (HPA) System Regulation (2007) (136)
- Heritability of Sleep Electroencephalogram (2008) (136)
- Allopregnanolone affects sleep in a benzodiazepine-like fashion. (1997) (135)
- Genetic Markers for PTSD Risk and Resilience Among Survivors of the World Trade Center Attacks (2011) (134)
- Placental glucose transporter expression is regulated by glucocorticoids. (1999) (134)
- Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression (2005) (133)
- Interleukin‐1β Stimulates both Central and Peripheral Release of Vasopressin and Oxytocin in the Rat (1995) (133)
- Neuropeptides and human sleep. (1997) (133)
- Functional antagonism of gonadal steroids at the 5-hydroxytryptamine type 3 receptor. (1998) (132)
- Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men (2000) (132)
- Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects. (2003) (132)
- The Corticotropin-Releasing Hormone Network and the Hypothalamic-Pituitary-Adrenal Axis: Molecular and Cellular Mechanisms Involved (2011) (131)
- Forced swimming evokes a biphasic response in CREB phosphorylation in extrahypothalamic limbic and neocortical brain structures in the rat (2002) (130)
- Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss (2013) (128)
- Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans (2014) (128)
- Cortisol, ACTH, and cardiovascular response to a cognitive challenge paradigm in aging and depression. (1995) (127)
- Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior (2008) (127)
- Neuroendocrine and Behavioral Effects of Repetitive Transcranial Magnetic Stimulation in a Psychopathological Animal Model Are Suggestive of Antidepressant-like Effects (2001) (127)
- Proteomics and Metabolomics Analysis of a Trait Anxiety Mouse Model Reveals Divergent Mitochondrial Pathways (2011) (126)
- High-Affinity CRF1 Receptor Antagonist NBI-34041: Preclinical and Clinical Data Suggest Safety and Efficacy in Attenuating Elevated Stress Response (2007) (126)
- Effects of rapid eye movement sleep deprivation on fear extinction recall and prediction error signaling (2012) (125)
- Weight loss causes neuroendocrine disturbances: experimental study in healthy starving subjects (1986) (125)
- Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results. (2003) (125)
- Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor (2003) (124)
- Identification and characterization of a 3',5'-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter. (1992) (123)
- Effect of Ethanol on Hypothalamic–Pituitary–Adrenal System Response to Psychosocial Stress in Sons of Alcohol-Dependent Fathers (2004) (123)
- Atrial natriuretic factor inhibits the CRH-stimulated secretion of ACTH and cortisol in man. (1992) (122)
- Valproate and Amitriptyline Exert Common and Divergent Influences on Global and Gene Promoter-Specific Chromatin Modifications in Rat Primary Astrocytes (2010) (122)
- Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man. (1995) (122)
- Human corticotropin-releasing hormone in depression—correlation with thyrotropin secretion following thyrotropin-releasing hormone (1986) (121)
- Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients (2012) (121)
- GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment. (2002) (120)
- Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety (1998) (120)
- Fatigue and regulation of the hypothalamo-pituitary-adrenal axis in multiple sclerosis. (2005) (120)
- Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice (2008) (119)
- Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression. (2004) (119)
- Corticotropin-releasing hormone modulators and depression. (2003) (118)
- The modified hole board as a differential screen for behavior in rodents (2001) (117)
- Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavioral and neuroendocrine consequences of adverse early life events. (1997) (117)
- ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: Relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression (1984) (116)
- Glucocorticoids accelerate anti-T cell receptor-induced T cell growth. (1995) (115)
- Stimulation response to corticotropin-releasing hormone (CRH) in patients with depression, alcoholism and panic disorder. (1987) (113)
- The neural correlates and temporal sequence of the relationship between shock exposure, disturbed sleep and impaired consolidation of fear extinction. (2010) (113)
- Association of GSK3beta polymorphisms with brain structural changes in major depressive disorder. (2009) (113)
- Rapid eye movement-related brain activation in human sleep: a functional magnetic resonance imaging study (2005) (113)
- HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients (2009) (112)
- Maintenance of hippocampal cell numbers in young and aged rats submitted to chronic unpredictable stress. Comparison with the effects of corticosterone treatment. (1998) (112)
- Reduced hippocampus volume in the mouse model of Posttraumatic Stress Disorder. (2011) (111)
- CRF signaling: molecular specificity for drug targeting in the CNS. (2006) (111)
- Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice (2003) (111)
- Dysregulation of the hypothalamo-pituitary-adrenal axis is related to the clinical course of MS (1999) (110)
- The activated glucocorticoid receptor inhibits the transcription factor T‐bet by direct protein‐protein interaction (2007) (109)
- Meta-analysis of genome-wide association data detects a risk locus for major mood disorders on chromosome 3p21.1 (2009) (109)
- Influence of endotoxin on nocturnal sleep in humans. (1993) (109)
- Refining genetic associations in multiple sclerosis (2008) (108)
- Retinoic acid as a novel medical therapy for Cushing's disease in dogs. (2006) (108)
- Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder (2008) (108)
- DHEA administration increases rapid eye movement sleep and EEG power in the sigma frequency range. (1995) (108)
- Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome (2008) (108)
- Sleep in Schizophrenia: A Polysomnographic Study on Drug-Naive Patients (1997) (107)
- Protection Against Oxidative Stress‐induced Neuronal Cell Death‐A Novel Role for RU486 (1997) (106)
- Dysregulation of the Hypothalamic-Pituitary-Adrenocortical System in Panic Disorder (1996) (105)
- ACTH, cortisol, and corticosterone output after ovine corticotropin-releasing factor challenge during depression and after recovery (1985) (105)
- Mice with Mutations in the HPA-System as Models for Symptoms of Depression (2006) (105)
- Endocrine profile and neuroendocrine challenge tests in transgenic mice expressing antisense RNA against the glucocorticoid receptor. (1997) (104)
- Successful Antidepressant Therapy Restores the Disturbed Interplay Between TNF-α System and HPA Axis (2006) (104)
- The corticosterone synthesis inhibitor metyrapone prevents hypoxia/ischemia-induced loss of synaptic function in the rat hippocampus. (2000) (104)
- Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test. (2001) (104)
- The hypothalamic-pituitary-adrenocortical system and sleep in man. (1995) (103)
- Regulation of the Hypothalamic-Pituitary-Adrenocortical System in Mice Deficient for CRH Receptors 1 and 2. (2001) (102)
- Evidence supporting the match/mismatch hypothesis of psychiatric disorders (2014) (102)
- Glucocorticoid receptor impairment alters CNS responses to a psychological stressor: an in vivo microdialysis study in transgenic mice (2000) (101)
- Intact spatial learning and memory in transgenic mice with reduced BDNF (1997) (101)
- Plasma dexamethasone concentrations and differential suppression response of cortisol and corticosterone in depressives and controls. (1984) (100)
- High susceptibility to chronic social stress is associated with a depression-like phenotype (2010) (100)
- Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas (2005) (99)
- Pharmacogenomics and antidepressant drugs (2006) (98)
- Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stress (2015) (98)
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- Genetic Variants in the ABCB1 Gene Determine Bioavailability of Antidepressants in the Brain (2017) (0)
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- Untersuchung über den Einfluß von Nordiazepam auf die Plasmakonzentration von Amitriptylin und Nortriptylin (1986) (0)
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- ENDOTOXIN‐ AND CORTICOTROPIN‐RELEASING HORMONE (CRH) ‐ INDUCED RELEASE OF ACTH AND CORTISOL: A COMPARATIVE STUDY IN HUMAN MALES (1992) (0)
- Psychopathological, cognitive and neuroendocrine responses to treatment with amitriptyline in elderly depressed patients (1991) (0)
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- 27th Annual Meeting of the Swiss Society of Biological Psychiatry (2007) (0)
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- Modern Psychiatry : From Genes to Therapies ' Modern Psychiatry : From Genes to Therapies ( (2010) (0)
- Subject Index Vol. 70, 1999 (1999) (0)
- Limbic NF-KB signalling controls stress-induced anxiety and antidepressant effects independently of the HPA axis (2010) (0)
- FKBP51 and FKBP52 differentially regulate corticosteroid receptors at distinct levels: Importance of the peptidylprolyl isomerase domain (2004) (0)
- Severe trauma moderates the relationship between variations in the vasopressin receptor 1A gene (AVPR1A) and depression in a family-based association lest (2008) (0)
- Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder (2018) (0)
- MRI used as tool to quantify white matter pathology and its interaction with vascular risk factors in depression (2013) (0)
- Plasma dexamethasone kinetics during the dexamethasone suppression test after oral and intravenous administration of the test drug to patients with depression (1987) (0)
- Reply (1999) (0)
- Expressing emotions: Avp and Crh are involved in the phenotype of mice bred for extremes in anxiety-related behavior (2007) (0)
- 22. Symposium of the AGNP, Nuremberg, September 26th to 29th, 2001. Editorial. (2001) (0)
- CENTRAL CORTICOTROPIN-RELEASING HORMONE OVEREXPRESSION ENHANCES REM SLEEP IN CONDITIONAL TRANSGENIC MICE (2009) (0)
- Polymorphisms in the angiotensin converting enzyme (ACE) gene are associated with unipolar depression, ACE activity and hypercortisolism (2005) (0)
- Vorkommen und Funktion des toll-like Rezeptor 2 in follikulostellaren Hypophysenzellen (2012) (0)
- The neuropeptide galanin increases rem latency and alleviates depressed mood in patients with depression (2003) (0)
- Neddylation, a new post-translational modification, controls dendrite and synapse development (2012) (0)
- Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men. (2023) (0)
- Sleep and hormones (1991) (0)
- Polymorphisms of the dopamine beta-hydroxylase (DBH) gene show associations with cognitive flexibility in mentally healthy adults (2009) (0)
- Cortisol levels and gene expression changes in posttraumatic stress disorder: the role of endophenotypes in determining common biological pathways in psychiatric disorders (2010) (0)
- Cytokines enhance target cell sensitivity to glucocorticoids (1996) (0)
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What Schools Are Affiliated With Florian Holsboer?
Florian Holsboer is affiliated with the following schools: