Frances Brodsky
#63,791
Most Influential Person Now
American cell biologist
Frances Brodsky's AcademicInfluence.com Rankings
Frances Brodskybiology Degrees
Biology
#2700
World Rank
#4259
Historical Rank
#1183
USA Rank
Cell Biology
#200
World Rank
#207
Historical Rank
#49
USA Rank
Biochemistry
#2492
World Rank
#2650
Historical Rank
#336
USA Rank
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Biology
Frances Brodsky's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Frances Brodsky Influential?
(Suggest an Edit or Addition)According to Wikipedia, Frances Brodsky is an American cell biologist. She is known for her work on clathrin and its role in the function of the immune system. She is a professor of cell biology and the director of the Division of Biosciences at University College London. She is the author of three scientific mystery novels under the pseudonym B.B. Jordan. She was the founding editor of the journal Traffic.
Frances Brodsky's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission (2008) (716)
- Biological basket weaving: formation and function of clathrin-coated vesicles. (2001) (686)
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds (2013) (637)
- EGF Receptor Signaling Stimulates SRC Kinase Phosphorylation of Clathrin, Influencing Clathrin Redistribution and EGF Uptake (1999) (367)
- Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment (1990) (356)
- The cell biology of antigen processing and presentation. (1991) (352)
- Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells (2002) (330)
- Characterization of a monoclonal anti‐β2‐microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens (1979) (298)
- Living with clathrin: its role in intracellular membrane traffic. (1988) (279)
- Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4. (1998) (270)
- Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression. (1999) (241)
- Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization. (2002) (240)
- TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis (2005) (211)
- A cost–benefit analysis of the physical mechanisms of membrane curvature (2013) (193)
- Diversity of clathrin function: new tricks for an old protein. (2012) (179)
- Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs (1995) (166)
- Folding and trimerization of clathrin subunits at the triskelion hub (1992) (164)
- Clathrin self-assembly is mediated by a tandemly repeated superhelix (1999) (156)
- Adp-Ribosylation Factor 6 and Endocytosis at the Apical Surface of Madin-Darby Canine Kidney Cells (1999) (147)
- Inhibition of endocytosis by anti-clathrin antibodies (1986) (146)
- NGF Signals through TrkA to Increase Clathrin at the Plasma Membrane and Enhance Clathrin-Mediated Membrane Trafficking (2000) (142)
- A Dominant-negative Clathrin Mutant Differentially Affects Trafficking of Molecules with Distinct Sorting Motifs in the Class II Major Histocompatibility Complex (MHC) Pathway (1998) (133)
- Plasticity of B cell receptor internalization upon conditional depletion of clathrin. (2005) (130)
- Huntingtin-interacting Protein 1 (Hip1) and Hip1-related Protein (Hip1R) Bind the Conserved Sequence of Clathrin Light Chains and Thereby Influence Clathrin Assembly in Vitro and Actin Distribution in Vivo* (2005) (114)
- Evolutionary analysis and molecular dissection of caveola biogenesis (2008) (112)
- Cellular and subcellular distribution of PBP72/74, a peptide-binding protein that plays a role in antigen processing. (1991) (111)
- 100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties (1992) (108)
- A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism (2009) (107)
- Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics. (1991) (105)
- Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization (2011) (105)
- Adaptor self‐aggregation, adaptor‐receptor recognition and binding of alpha‐adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin‐coated pits. (1993) (102)
- 100-kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis. (1989) (98)
- Hypersensitivity to nonsteroidal anti-inflammatory drugs (1995) (93)
- Actin Binding by Hip1 (Huntingtin-interacting Protein 1) and Hip1R (Hip1-related Protein) Is Regulated by Clathrin Light Chain* (2008) (91)
- Clathrin self‐assembly is regulated by three light‐chain residues controlling the formation of critical salt bridges (1998) (91)
- Human pathogen subversion of antigen presentation (1999) (85)
- Clathrin structure characterized with monoclonal antibodies. II. Identification of in vivo forms of clathrin (1985) (82)
- Conformation switching of clathrin light chain regulates clathrin lattice assembly. (2010) (79)
- Predominance of clathrin light chain LCb correlates with the presence of a regulated secretory pathway (1990) (78)
- Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution. (2005) (67)
- The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step (2010) (67)
- A novel clathrin homolog that co‐distributes with cytoskeletal components functions in the trans‐Golgi network (2001) (66)
- The B Lymphocyte Adaptor Molecule of 32 Kilodaltons (Bam32) Regulates B Cell Antigen Receptor Internalization1 (2004) (64)
- Clathrin Hub Expression Dissociates the Actin‐Binding Protein Hip1R from Coated Pits and Disrupts Their Alignment with the Actin Cytoskeleton (2001) (62)
- T Cell Receptor Engagement Leads to Phosphorylation of Clathrin Heavy Chain during Receptor Internalization (2004) (61)
- Dimorphic Motifs in D0 and D1+D2 Domains of Killer Cell Ig-Like Receptor 3DL1 Combine to Form Receptors with High, Moderate, and No Avidity for the Complex of a Peptide Derived from HIV and HLA-A*24021 (2009) (61)
- Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. (2013) (60)
- Endocytosis Regulates Cell Soma Translocation and the Distribution of Adhesion Proteins in Migrating Neurons (2011) (60)
- Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization (2014) (59)
- Complete Reconstitution of Clathrin Basket Formation with Recombinant Protein Fragments: Adaptor Control of Clathrin Self‐Assembly (2000) (59)
- Clathrin self‐assembly involves coordinated weak interactions favorable for cellular regulation (2003) (59)
- Localization of clathrin light-chain sequences mediating heavy-chain binding and coated vesicle diversity (1987) (54)
- Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG (2012) (54)
- Clathrin light and heavy chain interface: α‐helix binding superhelix loops via critical tryptophans (2002) (53)
- Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitro. (1990) (52)
- Membrane Traffic in Skeletal Muscle (2004) (49)
- Novel Binding Sites on Clathrin and Adaptors Regulate Distinct Aspects of Coat Assembly (2006) (47)
- Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration. (2004) (47)
- Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration (2014) (44)
- Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling. (2001) (42)
- A Common Clathrin‐Mediated Machinery Co‐ordinates Cell–Cell Adhesion and Bacterial Internalization (2012) (42)
- New Faces of the Familiar Clathrin Lattice (2005) (40)
- Interactions of NK Cell Receptor KIR3DL1*004 with Chaperones and Conformation-Specific Antibody Reveal a Functional Folded State As Well As Predominant Intracellular Retention (2011) (38)
- "Bare lymphocytes" without immunodeficiency. (1983) (37)
- The Interaction of Calmodulin with Clathrin-coated Vesicles, Triskelions, and Light Chains (1995) (34)
- Hybrid myeloma monoclonal antibodies against MHC products (1979) (34)
- Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension (2019) (33)
- Enhanced interaction of HLA-DM with HLA-DR in enlarged vacuoles of hereditary and infectious lysosomal diseases. (1999) (33)
- Role of clathrin in the regulated secretory pathway of pancreatic beta-cells. (2001) (32)
- New fashions in vesicle coats. (1997) (30)
- Antigen processing and presentation: close encounters in the endocytic pathway. (1992) (26)
- Hsc70-induced Changes in Clathrin-Auxilin Cage Structure Suggest a Role for Clathrin Light Chains in Cage Disassembly (2013) (26)
- Monoclonal Antibodies as Magic Bullets (2004) (25)
- Monoclonal antimacrophage antibodies: human pulmonary macrophages express HLA-DR (Ia-like) antigens in culture. (2015) (25)
- Evolution of HLA antigenic determinants: Species cross-reactions of monoclonal antibodies (2004) (24)
- Clathrin light chains’ role in selective endocytosis influences antibody isotype switching (2016) (24)
- Unconventional functions for clathrin, ESCRTs, and other endocytic regulators in the cytoskeleton, cell cycle, nucleus, and beyond: links to human disease. (2014) (23)
- CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis (2019) (23)
- The CHC22 Clathrin-GLUT4 Transport Pathway Contributes to Skeletal Muscle Regeneration (2013) (23)
- Lipid Metabolism Links Nutrient-Exercise Timing to Insulin Sensitivity in Men Classified as Overweight or Obese (2019) (23)
- NO sex please⃛ (1998) (22)
- CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function (2017) (21)
- Stealth, sabotage and exploitation (1999) (20)
- Evolutionary cell biology: Lessons from diversity (2012) (19)
- The adaptor protein GULP promotes Jedi-1–mediated phagocytosis through a clathrin-dependent mechanism (2014) (19)
- Molecular Structures of Proteins Involved in Vesicle Coat Formation (2000) (18)
- Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism (2019) (17)
- Clathrin's life beyond 40: Connecting biochemistry with physiology and disease. (2020) (17)
- Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo (2019) (16)
- Molecular Structures of Proteins Involved in Vesicle Fusion (2000) (16)
- Building GLUT4 Vesicles: CHC22 Clathrin's Human Touch. (2020) (15)
- The intracellular traffic of immunologically active molecules. (1984) (15)
- The AP2 adaptor enhances clathrin coat stiffness (2019) (14)
- A matrix approach to human class II histocompatibility antigens: Reactions of four monoclonal antibodies with the products of nine haplotypes (2004) (13)
- The Clathrin-Binding Domain of CALM-AF10 Alters the Phenotype of Myeloid Neoplasms in Mice (2011) (12)
- Anisotropic nanocrystal arrays organized on protein lattices formed by recombinant clathrin fragments. (2012) (9)
- The invariant dating service (1990) (9)
- Role of clathrin in the regulated secretory pathway of pancreatic β-cells (9)
- A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule (2015) (7)
- Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain. (2010) (7)
- Antagonistic regulation controls clathrin-mediated endocytosis: AP2 adaptor facilitation vs restraint from clathrin light chains. (2021) (6)
- Intracellular colocalization of molecules involved in antigen processing and presentation by B cells. (1989) (6)
- Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate (2022) (5)
- Intracellular routes for antigen processing and presentation. (1991) (5)
- Green Light for Traffic (2000) (5)
- Life History of the Journal TRAFFIC, Celebrating Ten Years of Publication (2010) (5)
- CHC22 clathrin initiates biogenesis of the human GLUT4 storage compartment from the early secretory pathway (2018) (4)
- Cell biology: Clathrin's Achilles' ankle (2004) (4)
- Expression Mechanisms for Affecting Class I MHC Cutting Edge : Adenovirus E 19 Has Two and (1999) (4)
- Clathrin and Clathrin-Dependent Endocytosis (2016) (4)
- CHC22 Clathrin Diverts GLUT4 from the ER-to-Golgi Intermediate Compartment for Intracellular Sequestration (2018) (3)
- A new direction for Traffic (2020) (2)
- Tropomyosin-like Properties of Clathrin a Rapid, High-yield Purification Light Chains Allow (1983) (2)
- Twenty years of Traffic (2020) (2)
- Lipid rafts unite signaling cascades with clathrin to regulate B cell antigen receptor internalization (2002) (2)
- The long and short of adaptor appendages (2003) (2)
- Endocytosis: Molecular Mechanism and Role in the Immune Response (1992) (2)
- Doing it the institutional way (1991) (1)
- Into the fast lane with MEDLINE! (2001) (1)
- The CHC 22 Clathrin-GLUT 4 Transport Pathway Contributes to Skeletal Muscle Regeneration (2013) (1)
- What's the score? (1991) (1)
- Clathrin light chain diversity regulates lattice properties and efficiency of synaptic vesicle formation (2019) (1)
- Crystal Structure of the huntingtin interacting protein 1 coiled coil domain (2010) (1)
- Dataset for "Lipid metabolism links nutrient-exercise timing to insulin sensitivity in overweight men" (2019) (1)
- Pathogen subversion of cellular immunity (1999) (1)
- Identifying a GSK3-TRARG1 signaling axis reveals BCL9L as a novel regulator of GLUT4 trafficking (2020) (1)
- Analysis of coated vesicle structure and function using anti-clathrin monoclonal antibodies. (1988) (1)
- Epithelial lumen development requires differential participation of the vertebrate clathrin light chain isoforms with dominance of CLCa in vivo (2023) (0)
- INTRACELLULAR PATHWAYS FOR TRANSPORT OF CLASS-II MHC MOLECULES (1993) (0)
- Biology 100-kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis ( adaptors / assembly polypeptides / transferrin / liposomes ) (0)
- Crystal structure of a clathrin heavy chain and clathrin light chain complex (2010) (0)
- Cooperative weak interactions make a strong basket: the paradox of clathrin assembly (2002) (0)
- CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) (1999) (0)
- is required for actin recruitment at sites of and (2011) (0)
- [The CHC22 human clathrin heavy chain isoform, intracellular traffic of the glucose transporter GLUT4, and type 2 diabetes]. (2010) (0)
- Evolution of the CLTCL1 Gene Encoding CHC22 Clathrin Reveals Selection Influencing CHC22’s Role in Human Glucose Metabolism (2018) (0)
- Traffic Changes with Increased Flow (2002) (0)
- Traffic is Gaining Momentum (2001) (0)
- Pathways regulating the internalization of activated immune receptors (2005) (0)
- Transport of Proteins and Membrane in Eukaryotic Cells (Göttingen, September 29–October 1, 1999) (2000) (0)
- The CHC22 human clathrin heavy chain isoform is involved in the cellular trafic of the glucose transporter GLUT4 (2010) (0)
- Evolution and function of a novel clathrin isoform (2009) (0)
- The interface of clathrin heavy and light chain contact (2002) (0)
- In Memoriam: Peter Hartmann (1946‐2020), publisher, colleague, and friend (2020) (0)
- ARF6 and ARNO regulate a dynamin and clathrin dependent endocytosis pathway at the apical surface of MDCK cells. (1999) (0)
- The evolution of CHC22 clathrin influences its role in human glucose metabolism (2018) (0)
- Editorial (2003) (0)
- A potential role for the second isoform of clathrin heavy chain in skeletal muscle (2002) (0)
- Evidence for a novel vesicular epitope in muscle cells with homology to AP-180. (1996) (0)
- Clathrin heavy chain CHC22 impairs mice skeletal muscle regeneration (2013) (0)
- Open Access to Traffic (2003) (0)
- Klein or Kipling? (1990) (0)
- Predominant Intracellular Retention Functional Folded State As Well As Conformation-Specific Antibody Reveal a KIR3DL1*004 with Chaperones and Interactions of NK Cell Receptor (2010) (0)
- Insight into the intra- and inter-molecular interactions of clathrin isoforms CHC17 and CHC22. (2023) (0)
- Looking back to traffic forward: A tribute to Thomas Kreis (1952‐1998) and his inspiration (2020) (0)
- HLA-DR in Enlarged Vacuoles of Hereditary Enhanced Interaction of HLA-DM with (1998) (0)
- Molecule Retention of the Patr-AL MHC Class I Low Surface Expression and Intracellular A Distinctive Cytoplasmic Tail Contributes to (2015) (0)
- Intracellular Trafficking of Proteins. Intercellular and Intracellular Communications.Clifford J. Steer , John A. Hanover (1993) (0)
- Structural Analysis of the Clathrin Triskelion (1993) (0)
- Structure-function studies of clathrin subunits and their interaction (2000) (0)
- Editorial overview: Membrane traffic in the time of COVID-19 (2020) (0)
- Analysis of Clathrin Self-Assembly by Infrared Spectroscopy (2010) (0)
- CHC22 clathrin membrane recruitment uses SNX5 in bipartite interaction with secretory tether p115 (2023) (0)
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