Francesc Villarroya
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Computer Science
Francesc Villarroya's Degrees
- PhD Computer Science University of Barcelona
- Masters Computer Science University of Barcelona
- Bachelors Computer Science University of Barcelona
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(Suggest an Edit or Addition)Francesc Villarroya's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue* (2011) (517)
- BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions (2012) (494)
- Brown adipose tissue as a secretory organ (2017) (439)
- White, brown, beige/brite: different adipose cells for different functions? (2013) (428)
- GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK (2014) (402)
- Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat. (2010) (343)
- Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. (2001) (324)
- Fibroblast growth factor 21 protects against cardiac hypertrophy in mice (2013) (287)
- Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation. (2011) (246)
- SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging. (2012) (215)
- Browning of White Adipose Cells by Intermediate Metabolites: An Adaptive Mechanism to Alleviate Redox Pressure (2014) (214)
- Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat (2011) (206)
- Fibroblast growth factor 21 protects the heart from oxidative stress. (2015) (204)
- Beyond the sympathetic tone: the new brown fat activators. (2013) (200)
- A Novel Regulatory Pathway of Brown Fat Thermogenesis (1995) (200)
- SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD* (2009) (190)
- PPARs in the Control of Uncoupling Proteins Gene Expression (2006) (187)
- Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy. (2008) (186)
- Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Controls Transcription of the Sirt3 Gene, an Essential Component of the Thermogenic Brown Adipocyte Phenotype* (2011) (183)
- An endocrine role for brown adipose tissue? (2013) (176)
- TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway. (2012) (175)
- Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients (2014) (166)
- The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes (2016) (160)
- Thiazolidinediones and Rexinoids Induce Peroxisome Proliferator-Activated Receptor-Coactivator (PGC)-1α Gene Transcription: An Autoregulatory Loop Controls PGC-1α Expression in Adipocytes via Peroxisome Proliferator-Activated Receptor-γ Coactivation (2006) (159)
- Retinoids and adipose tissues: metabolism, cell differentiation and gene expression (1999) (157)
- Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth. (1999) (157)
- HIV-1 Infection Alters Gene Expression in Adipose Tissue, Which Contributes to HIV-1/Haart-Associated Lipodystrophy (2005) (151)
- Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance (2017) (149)
- Inflammation of brown/beige adipose tissues in obesity and metabolic disease (2018) (144)
- Toward an Understanding of How Immune Cells Control Brown and Beige Adipobiology. (2018) (133)
- Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging (2015) (129)
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation. (2015) (127)
- Human dendritic cell activities are modulated by the omega‐3 fatty acid, docosahexaenoic acid, mainly through PPARγ:RXR heterodimers: comparison with other polyunsaturated fatty acids (2008) (126)
- Nadir CD4 T cell count as predictor and high CD4 T cell intrinsic apoptosis as final mechanism of poor CD4 T cell recovery in virologically suppressed HIV-infected patients: clinical implications. (2010) (121)
- CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation. (2018) (121)
- Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency (2018) (117)
- Reversible Inhibition of Mitochondrial Protein Synthesis during Linezolid-Related Hyperlactatemia (2006) (115)
- FGF19 and FGF21 serum concentrations in human obesity and type 2 diabetes behave differently after diet- or surgically-induced weight loss. (2017) (115)
- GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction (2016) (115)
- PPARd, but not PPARa, activates PGC-1a gene transcription in muscle (2007) (114)
- Fibroblast growth factor-21, energy balance and obesity (2015) (113)
- Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration (2017) (107)
- FGF21 mediates the lipid metabolism response to amino acid starvation (2013) (105)
- Overexpression of UCP3 in cultured human muscle lowers mitochondrial membrane potential, raises ATP/ADP ratio, and favors fatty acid versus glucose oxidation (2001) (101)
- Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy. (2013) (101)
- Uncoupling Protein-2 Controls Adiponectin Gene Expression in Adipose Tissue Through the Modulation of Reactive Oxygen Species Production (2007) (97)
- Drug-induced lipotoxicity: lipodystrophy associated with HIV-1 infection and antiretroviral treatment. (2010) (94)
- Irisin, turning up the heat. (2012) (93)
- A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction (2013) (92)
- Retinoids and retinoid receptors in the control of energy balance: novel pharmacological strategies in obesity and diabetes. (2004) (91)
- Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: the adipocyte as a target of anti-retroviral-induced mitochondrial toxicity. (2005) (91)
- FGF21 and Cardiac Physiopathology (2015) (88)
- New insights into the secretory functions of brown adipose tissue. (2019) (85)
- Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation. (2006) (83)
- Functional relationship between MyoD and peroxisome proliferator-activated receptor-dependent regulatory pathways in the control of the human uncoupling protein-3 gene transcription. (2003) (82)
- SIRT1 Is Involved in Glucocorticoid-mediated Control of Uncoupling Protein-3 Gene Transcription* (2007) (80)
- Adipose tissue biology and HIV-infection. (2011) (79)
- Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice (2016) (79)
- Alarmin high-mobility group B1 (HMGB1) is regulated in human adipocytes in insulin resistance and influences insulin secretion in β-cells (2014) (77)
- Ontogeny and perinatal modulation of gene expression in rat brown adipose tissue. Unaltered iodothyronine 5'-deiodinase activity is necessary for the response to environmental temperature at birth. (1990) (76)
- Lipodystrophy in HIV 1-infected patients: lessons for obesity research (2007) (74)
- Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue. (2014) (74)
- Thermogenic brown and beige/brite adipogenesis in humans (2015) (73)
- In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells (2006) (68)
- Uncoupling protein‐3 gene expression in skeletal muscle during development is regulated by nutritional factors that alter circulating non‐esterified fatty acids (1999) (67)
- Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: a role for Sirt1-Mef2 in adult heart. (2012) (67)
- Transcriptional regulation of the uncoupling protein-1 gene. (2017) (66)
- The Lives and Times of Brown Adipokines (2017) (64)
- Opposite regulation of PPAR-α and -γ gene expression by both their ligands and retinoic acid in brown adipocytes (1999) (64)
- Dominant negative regulation by c-Jun of transcription of the uncoupling protein-1 gene through a proximal cAMP-regulatory element: a mechanism for repressing basal and norepinephrine-induced expression of the gene before brown adipocyte differentiation. (1998) (63)
- CCAAT/enhancer binding proteins α and β are transcriptional activators of the brown fat uncoupling protein gene promoter (1994) (62)
- Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids. (2000) (62)
- PPARdelta, but not PPARalpha, activates PGC-1alpha gene transcription in muscle. (2007) (61)
- Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease (2017) (60)
- The human uncoupling protein‐3 gene promoter requires myod and is induced by retinoic acid in muscle cells (2000) (58)
- Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma (2016) (57)
- FGF21 expression and release in muscle cells: involvement of MyoD and regulation by mitochondria-driven signalling. (2014) (57)
- Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region. (2005) (56)
- Defective thermoregulation, impaired lipid metabolism, but preserved adrenergic induction of gene expression in brown fat of mice lacking C/EBPbeta. (2005) (56)
- 9-cis-Retinoic Acid (9cRA), a Retinoid X Receptor (RXR) Ligand, Exerts Immunosuppressive Effects on Dendritic Cells by RXR-Dependent Activation: Inhibition of Peroxisome Proliferator-Activated Receptor γ Blocks Some of the 9cRA Activities, and Precludes Them to Mature Phenotype Development1 (2007) (56)
- Mitochondrial Biogenesis and Thyroid Status Maturation in Brown Fat Require CCAAT/Enhancer-binding Protein α* (2002) (55)
- Differential gene expression indicates that ‘buffalo hump’ is a distinct adipose tissue disturbance in HIV-1-associated lipodystrophy (2008) (55)
- Effects of nevirapine and efavirenz on human adipocyte differentiation, gene expression, and release of adipokines and cytokines. (2011) (55)
- Adipokines and the Endocrine Role of Adipose Tissues. (2016) (53)
- Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat. (1987) (52)
- The chlorophyll-derived metabolite phytanic acid induces white adipocyte differentiation (2002) (52)
- Differential regulation of uncoupling protein-2 and uncoupling protein-3 gene expression in brown adipose tissue during development and cold exposure. (1998) (51)
- Serum FGF21 levels are elevated in association with lipodystrophy, insulin resistance and biomarkers of liver injury in HIV-1-infected patients (2010) (51)
- Phytanic acid, a novel activator of uncoupling protein-1 gene transcription and brown adipocyte differentiation. (2002) (51)
- Differential effects of efavirenz and lopinavir/ritonavir on human adipocyte differentiation, gene expression and release of adipokines and pro-inflammatory cytokines. (2010) (48)
- Regulation of mitochondrial biogenesis in brown adipose tissue: nuclear respiratory factor-2/GA-binding protein is responsible for the transcriptional regulation of the gene for the mitochondrial ATP synthase beta subunit. (1998) (48)
- SIRT1 signaling as potential modulator of skeletal muscle diseases. (2012) (47)
- Impact of elvitegravir on human adipocytes: Alterations in differentiation, gene expression and release of adipokines and cytokines. (2016) (46)
- SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation (2020) (45)
- Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene. (2000) (44)
- Peroxisome proliferator-activated receptors-α and -γ, and cAMP-mediated pathways, control retinol-binding protein-4 gene expression in brown adipose tissue. (2012) (43)
- Mitochondrial Uncoupling and the Regulation of Glucose Homeostasis. (2017) (43)
- Thermogenic activation represses autophagy in brown adipose tissue (2016) (42)
- Brown Adipocytes Secrete GDF15 in Response to Thermogenic Activation (2019) (42)
- Amino acid and glucose uptake by rat brown adipose tissue. Effect of cold-exposure and acclimation. (1988) (41)
- Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis (2016) (40)
- Mitochondrial DNA: An Up‐and‐coming Actor in White Adipose Tissue Pathophysiology (2009) (39)
- Induction of peroxisomal proliferator-activated receptor gamma and peroxisomal proliferator-activated receptor gamma coactivator 1 by unsaturated fatty acids, retinoic acid, and carotenoids in preadipocytes obtained from bovine white adipose tissue1,2. (2010) (38)
- Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway. (2016) (38)
- Peroxisome Proliferator-activated Receptor α Activates Transcription of the Brown Fat Uncoupling Protein-1 Gene (2001) (37)
- Effects of cold environment on mitochondrial genome expression in the rat: evidence for a tissue-specific increase in the liver, independent of changes in mitochondrial gene abundance. (1993) (37)
- Relationship between HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome and stavudine-triphosphate intracellular levels in patients with stavudine-based antiretroviral regimens. (2010) (37)
- CCAAT/enhancer-binding proteins alpha and beta in brown adipose tissue: evidence for a tissue-specific pattern of expression during development. (1994) (37)
- ETS transcription factors regulate the expression of the gene for the human mitochondrial ATP synthase beta-subunit. (1994) (36)
- Differentially Altered Molecular Signature of Visceral Adipose Tissue in HIV-1–Associated Lipodystrophy (2013) (36)
- Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids. (2007) (36)
- Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy. (2015) (34)
- HIV-1-infected long-term non-progressors have milder mitochondrial impairment and lower mitochondrially-driven apoptosis in peripheral blood mononuclear cells than typical progressors. (2007) (33)
- SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation (2020) (33)
- Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPδ. (2012) (33)
- Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans (2016) (33)
- Sequential changes in brown adipose tissue composition, cytochrome oxidase activity and GDP binding throughout pregnancy and lactation in the rat. (1986) (32)
- Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance (2017) (32)
- Effects of Rilpivirine on Human Adipocyte Differentiation, Gene Expression, and Release of Adipokines and Cytokines (2012) (32)
- Mitochondrial biogenesis in brown adipose tissue is associated with differential expression of transcription regulatory factors (2002) (31)
- Fgf21 is required for cardiac remodeling in pregnancy (2017) (31)
- Bovine sirtuins: initial characterization and expression of sirtuins 1 and 3 in liver, muscle, and adipose tissue. (2011) (31)
- Resveratrol induces nuclear factor-κB activity in human cardiac cells. (2013) (31)
- 9‐cis Retinoic acid induces the expression of the uncoupling protein‐2 gene in brown adipocytes (1998) (31)
- The endocrine role of brown adipose tissue: An update on actors and actions (2021) (30)
- Genetic and Functional Mitochondrial Assessment of HIV-Infected Patients Developing HAART-Related Hyperlactatemia (2009) (30)
- Iodothyronine 5'-deiodinase activity as an early event of prenatal brown-fat differentiation in bovine development. (1989) (30)
- Iodothyronine 5'-deiodinase activity in rat brown adipose tissue during development. (1987) (30)
- Hiv-1 Tat Protein Impairs Adipogenesis and Induces the Expression and Secretion of Proinflammatory Cytokines in Human Sgbs Adipocytes (2012) (30)
- Uncoupling protein 1 gene expression implicates brown adipocytes in highly active antiretroviral therapy-associated lipomatosis (2004) (30)
- Searching for Classical Brown Fat in Humans: Development of a Novel Human Fetal Brown Stem Cell Model (2016) (30)
- Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue-derived endocrine factor with a potential role in fetal growth. (2016) (29)
- Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency (2016) (29)
- The Beneficial Effects of Brown Fat Transplantation: Further Evidence of an Endocrine Role of Brown Adipose Tissue. (2015) (29)
- Opposite changes in meteorin-like and oncostatin m levels are associated with metabolic improvements after bariatric surgery (2018) (28)
- Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study (2019) (28)
- Fibroblast growth factor‐21 protects against fibrosis in hypertensive heart disease (2019) (27)
- Circulating FGF19 and FGF21 surge in early infancy from infra- to supra-adult concentrations (2015) (26)
- Autophagic control of cardiac steatosis through FGF21 in obesity-associated cardiomyopathy. (2018) (26)
- Overexpression of mitochondrial uncoupling protein‐3 does not decrease production of the reactive oxygen species, elevated by palmitate in skeletal muscle cells (2007) (26)
- Quality assessment of human mitochondrial DNA quantification: MITONAUTS, an international multicentre survey. (2011) (26)
- Histological and molecular features of lipomatous and nonlipomatous adipose tissue in familial partial lipodystrophy caused by LMNA mutations (2012) (25)
- Maraviroc reduces cytokine expression and secretion in human adipose cells without altering adipogenic differentiation. (2013) (25)
- Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis (2019) (25)
- Phytanic acid, but not pristanic acid, mediates the positive effects of phytol derivatives on brown adipocyte differentiation (2002) (25)
- Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation (2021) (24)
- Altered Expression of Nucleoside Transporter Genes (SLC28 and SLC29) in Adipose Tissue from HIV-1–Infected Patients (2007) (24)
- Opposite regulation of PPAR-alpha and -gamma gene expression by both their ligands and retinoic acid in brown adipocytes. (1999) (24)
- Cyanidin-3-O-glucoside restores insulin signaling and reduces inflammation in hypertrophic adipocytes. (2020) (24)
- Adaptative decrease in expression of the mRNA for uncoupling protein and subunit II of cytochrome c oxidase in rat brown adipose tissue during pregnancy and lactation. (1989) (24)
- Fibroblast growth factor 21 in breast milk controls neonatal intestine function (2015) (24)
- Adipogenic/Lipid, Inflammatory, and Mitochondrial Parameters in Subcutaneous Adipose Tissue of Untreated HIV-1–Infected Long-Term Nonprogressors: Significant Alterations Despite Low Viral Burden (2012) (24)
- Uncoupling protein‐3 sensitizes cells to mitochondrial‐dependent stimulus of apoptosis (2004) (24)
- Differential regulation of expression of genes encoding uncoupling proteins 2 and 3 in brown adipose tissue during lactation in mice. (2001) (23)
- Glucose tolerance and insulin response in offspring of ethanol-treated pregnant rats. (1985) (23)
- Effects of Switching from Stavudine to Raltegravir on Subcutaneous Adipose Tissue in HIV-Infected Patients with HIV/HAART-Associated Lipodystrophy Syndrome (HALS). A Clinical and Molecular Study (2014) (23)
- Lipotoxicity on the basis of metabolic syndrome and lipodystrophy in HIV-1-infected patients under antiretroviral treatment. (2010) (22)
- Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue (2018) (22)
- Oncostatin m impairs brown adipose tissue thermogenic function and the browning of subcutaneous white adipose tissue (2017) (22)
- Altered expression of master regulatory genes of adipogenesis in lipomas from patients bearing tRNA(Lys) point mutations in mitochondrial DNA. (2006) (22)
- Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet (2014) (22)
- The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism. (2004) (22)
- In Vivo Effects of Highly Active Antiretroviral Therapies Containing the Protease Inhibitor Nelfinavir on Mitochondrially Driven Apoptosis (2005) (22)
- Ontogeny of thyroid hormone receptors and c-erbA expression during brown adipose tissue development: evidence of fetal acquisition of the mature thyroid status. (1993) (21)
- Fibroblast Growth Factor-21 and the Beneficial Effects of Long-Chain n-3 Polyunsaturated Fatty Acids (2014) (21)
- Non-sympathetic control of brown adipose tissue. (2015) (21)
- CCAAT/enhancer binding proteins alpha and beta are transcriptional activators of the brown fat uncoupling protein gene promoter. (1994) (21)
- Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health (2021) (21)
- Cardiokines as Modulators of Stress-Induced Cardiac Disorders. (2017) (21)
- Meteorin-like/Meteorin-β protects heart against cardiac dysfunction (2021) (21)
- Inverse distribution of uncoupling proteins expression and oxidative capacity in mature adipocytes and stromal‐vascular fractions of rat white and brown adipose tissues (1999) (21)
- UCP3 Expression in Liver Modulates Gene Expression and Oxidative Metabolism in Response to Fatty Acids, and Sensitizes Mitochondria to Permeability Transition (2009) (19)
- Brown adipose tissue in prepubertal children: associations with sex, birthweight, and metabolic profile (2018) (19)
- HIV-1 Infection and the PPARγ-Dependent Control of Adipose Tissue Physiology (2008) (19)
- Co-ordinate decrease in the expression of the mitochondrial genome and nuclear genes for mitochondrial proteins in the lactation-induced mitochondrial hypotrophy of rat brown fat. (1995) (19)
- Building of a flexible microfluidic plasmo-nanomechanical biosensor for live cell analysis (2019) (18)
- Thymidine Kinase 2 Deficiency-Induced Mitochondrial DNA Depletion Causes Abnormal Development of Adipose Tissues and Adipokine Levels in Mice (2011) (18)
- Hepatectomy-nephrectomy effects in the pregnant rat and fetus. (1985) (18)
- Reduced Levels of Serum FGF19 and Impaired Expression of Receptors for Endocrine FGFs in Adipose Tissue From HIV-Infected Patients (2012) (18)
- Lipoprotein lipase mRNA expression in brown adipose tissue: translational and/or posttranslational events are involved in the modulation of enzyme activity. (1990) (17)
- BMP8 and activated brown adipose tissue in human newborns (2021) (17)
- High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients. (2017) (17)
- Infrared Thermography for Estimating Supraclavicular Skin Temperature and BAT Activity in Humans: A Systematic Review (2019) (17)
- Resistin and visfatin in steatotic and non-steatotic livers in the setting of partial hepatectomy under ischemia-reperfusion. (2014) (17)
- Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development (2021) (17)
- Developmental and tissue-specific involvement of peroxisome proliferator-activated receptor-alpha in the control of mouse uncoupling protein-3 gene expression. (2006) (16)
- Differential Effects of Retinoic Acid on White and Brown Adipose Tissues: An Unexpected Role for Vitamin A Derivatives on Energy Balance a (1998) (16)
- Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report (2008) (16)
- The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity (2020) (16)
- Impaired basal and noradrenaline-induced iodothyronine 5'-deiodinase activity in brown adipose tissue from pregnant and lactating rats. (1986) (15)
- Bhlhe40 Represses PGC-1α Activity on Metabolic Gene Promoters in Myogenic Cells (2015) (15)
- The protective effect of fibroblast growth factor‐21 in alcoholic cardiomyopathy: a role in protecting cardiac mitochondrial function (2020) (15)
- Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment. (2016) (15)
- SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2 (2020) (15)
- C/EBPβ is required in pregnancy-induced cardiac hypertrophy. (2016) (14)
- A 48-Week Study of Fat Molecular Alterations in HIV Naive Patients Starting Tenofovir/Emtricitabine With Lopinavir/Ritonavir or Efavirenz (2014) (14)
- Reduced circulating levels of chemokine CXCL14 in adolescent girls with polycystic ovary syndrome: normalization after insulin sensitization (2020) (14)
- Secretory Proteome of Brown Adipocytes in Response to cAMP-Mediated Thermogenic Activation (2019) (14)
- Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy (2020) (13)
- Evidence for a differential physiological modulation of brown fat iodothyronine 5'-deiodinase activity in the perinatal period. (1988) (13)
- The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell Lineages (2015) (13)
- HIV Type-1 Transgene Expression in Mice Alters Adipose Tissue and Adipokine Levels: Towards a Rodent Model of HIV Type-1 Lipodystrophy (2010) (13)
- Lithium inhibits brown adipocyte differentiation (2005) (13)
- BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies (2015) (13)
- Circulating growth-and-differentiation factor-15 in early life: relation to prenatal and postnatal growth and adiposity measurements (2019) (12)
- Association of Thymidylate Synthase Gene Polymorphisms with Stavudine Triphosphate Intracellular Levels and Lipodystrophy (2011) (12)
- Reduced noradrenaline turnover in brown adipose tissue of lactating rats. (1987) (12)
- Uridine Metabolism in HIV-1-Infected Patients: Effect of Infection, of Antiretroviral Therapy and of HIV-1/ART-Associated Lipodystrophy Syndrome (2010) (12)
- Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System (2018) (11)
- Activation of mitochondrial-driven apoptosis in skeletal muscle cells is not mediated by reactive oxygen species production. (2007) (11)
- Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling (2018) (11)
- Identification of tissue-specific protein binding domains in the 5'-proximal regulatory region of the rat mitochondrial brown fat uncoupling protein gene. (1994) (11)
- Similar metabolic response to acute ethanol intake in pregnant and non-pregnant rats either fed or fasted. (2011) (11)
- Association of Thymidylate Synthase Polymorphisms with Acute Pancreatitis and/or Peripheral Neuropathy in HIV-Infected Patients on Stavudine-Based Therapy (2013) (11)
- Gene expression of leptin and uncoupling proteins: molecular end-points of fetal development. (2001) (11)
- CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina (2021) (11)
- Zidovudine/lamivudine but not nevirapine in combination with lopinavir/ritonavir decreases subcutaneous adipose tissue mitochondrial DNA (2012) (11)
- Potential role of the melanocortin signaling system interference in the excess weight gain associated to some antiretroviral drugs in people living with HIV (2020) (11)
- Effects of docosahexanoic acid supplementation on inflammatory and subcutaneous adipose tissue gene expression in HIV‐infected patients on combination antiretroviral therapy (cART). A sub‐study of a randomized, double‐blind, placebo‐controlled study (2018) (11)
- Differential regulation of expression of genes encoding uncoupling proteins 2 and 3 in brown adipose tissue during lactation in mice (2001) (11)
- Elevated Levels of Circulating miR-92a Are Associated with Impaired Glucose Homeostasis in Patients with Obesity and Correlate with Metabolic Status After Bariatric Surgery (2019) (10)
- GDF11 induces mild hepatic fibrosis independent of metabolic health (2020) (10)
- Altered GDF15 and FGF21 Levels in Response to Strenuous Exercise: A Study in Marathon Runners (2020) (10)
- Changes in liver iodothyronine 5'-deiodinase activity during pregnancy and lactation in the rat. (1987) (10)
- Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21 (2019) (10)
- Mechanisms of antiretroviral-induced mitochondrial dysfunction in adipocytes and adipose tissue: in-vitro, animal and human adipose tissue studies (2007) (10)
- FGF15/19 is required for adipose tissue plasticity in response to thermogenic adaptations (2020) (10)
- Sirt1 mediates the effects of a short-term high-fat diet on the heart. (2015) (10)
- The chemokine CXCL14 is negatively associated with obesity and concomitant type-2 diabetes in humans (2021) (10)
- Pharmacogenetics of the lipodystrophy syndrome associated with HIV infection and combination antiretroviral therapy (2011) (10)
- GPR120 controls neonatal brown adipose tissue thermogenic induction. (2019) (10)
- Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients (2013) (9)
- Circulating fibroblast growth factor 23 (FGF23) levels are associated with metabolic disturbances and fat distribution but not cardiovascular risk in HIV-infected patients. (2015) (9)
- Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21. (2021) (9)
- Low-Dose Spironolactone-Pioglitazone-Metformin Normalizes Circulating Fetuin-A Concentrations in Adolescent Girls with Polycystic Ovary Syndrome (2018) (9)
- Developmental regulation of the intestinal FGF19 system in domestic pigs. (2018) (8)
- Effects of maternal hypocaloric diet feeding on neonatal rat brown adipose tissue. (1988) (8)
- Nerve Growth Factor Levels in Term Human Infants: Relationship to Prenatal Growth and Early Postnatal Feeding (2018) (8)
- Brown Adipokines. (2019) (8)
- Brown adipose tissue activity in hypocaloric-diet fed lactating rats (1986) (7)
- Potential role of sirtuins in livestock production. (2013) (7)
- Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice. (2021) (7)
- Changes in brown adipose tissue lipoprotein lipase activity and lipogenesis rate during pregnancy and lactation in the rat. (1986) (7)
- Transcription of the human uncoupling protein 3 gene is governed by a complex interplay between the promoter and intronic sequences (2009) (7)
- Effects of docosahexanoic acid on metabolic and fat parameters in HIV-infected patients on cART: A randomized, double-blind, placebo-controlled study. (2017) (6)
- Epitope mapping of mitochondrial adenine nucleotide translocase-1 in idiopathic dilated cardiomyopathy. (2002) (6)
- Lactate induces expression and secretion of fibroblast growth factor-21 by muscle cells (2018) (6)
- The importance of brown adipose tissue. (2009) (6)
- Liver volume and hepatic adiposity in childhood: relations to body growth and visceral fat (2018) (6)
- Effect of resveratrol and lipoic acid on sirtuin-regulated expression of metabolic genes in bovine liver and muscle slice cultures. (2015) (6)
- Inhibition of Iodothyronine 5′-Deiodinase by Iopanoic Acid Does Not Block Nuclear T3 Accumulation During Rat Fetal Development (1994) (6)
- A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice (2021) (5)
- A role for Oncostatin M in the impairment of glucose homeostasis in obesity. (2019) (5)
- Iodothyronine 5'-deiodinase activity and thyroid hormone content in brown adipose tissue during the breeding cycle of the rat. (1988) (5)
- Nicotinamide Protects Against Diet-Induced Body Weight Gain, Increases Energy Expenditure and Induces White Adipose Tissue Beiging. (2021) (5)
- The relative deficit of GDF15 in adolescent girls with PCOS can be changed into an abundance that reduces liver fat (2021) (5)
- Pharmacological and gene modification-based models for studying the impact of perinatal metabolic disturbances in adult life. (2009) (5)
- Comparison of effects of different anticoagulants and sample handling procedures on rat insulin radioimmunoassay. (1985) (5)
- ARMCX3 Mediates Susceptibility to Hepatic Tumorigenesis Promoted by Dietary Lipotoxicity (2021) (5)
- Complement Factor D (adipsin) Levels Are Elevated in Acquired Partial Lipodystrophy (Barraquer–Simons syndrome) (2021) (5)
- Use of Infrared Thermography to Estimate Brown Fat Activation After a Cooling Protocol in Patients with Severe Obesity That Underwent Bariatric Surgery (2020) (4)
- FGF21 serum levels are related to insulin resistance, metabolic changes and obesity in Mexican people living with HIV (PLWH) (2021) (4)
- Posterior Cervical Brown Fat and CXCL14 levels in the First Year of Life: Sex Differences and Association with Adiposity. (2021) (4)
- Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice (2022) (4)
- Influence of thyroid hormones on the human ATP synthase β-subunit gene promoter (1996) (4)
- Overexpression of CERKL Protects Retinal Pigment Epithelium Mitochondria from Oxidative Stress Effects (2021) (3)
- Hypertrophied Facial Fat in An HIV-1-Infected Patient after Autologous Transplantation from ‘Buffalo Hump’ Retains a Partial Brown-Fat-Like Molecular Signature (2013) (3)
- Effects of chronic ethanol treatment on glucose tolerance, insulin response and circulating metabolites in the pregnant rat. (1985) (3)
- Effects of ethinylestradiol-cyproterone acetate vs. pioglitazone-flutamide-metformin on plasma FGF21 levels in adolescent girls with androgen excess. (2016) (3)
- Nutritional and metabolic regulation of brown and beige adipose tissues (2020) (2)
- 22nd European Congress on Obesity (ECO2015), Prague, Czech Republic, May 6-9, 2015: Abstracts (2015) (2)
- Bone Morphogenetic Protein-8B Levels at Birth and in the First Year of Life: Relation to Metabolic-Endocrine Variables and Brown Adipose Tissue Activity (2022) (2)
- CCAAT/enhancer-binding proteins a and in brown adipose tissue: evidence for a tissue-specific pattern of expression during development (2005) (2)
- Differential association between S100A4 levels and insulin resistance in prepubertal children and adult subjects with clinically severe obesity (2019) (2)
- White adipose tissue-infiltrated CD11b+ myeloid cells are a source of S100A4, a new potential marker of hepatic damage. (2021) (2)
- Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation (2022) (2)
- Cardiotrophin‐1 contributes to metabolic adaptations through the regulation of lipid metabolism and to the fasting‐induced fatty acid mobilization (2020) (2)
- Influence of thyroid hormones on the human ATP synthase beta-subunit gene promoter. (1996) (1)
- Glucose metabolism "in vitro" in brown adipose tissue from pregnant and lactating rats. (1987) (1)
- Increased Circulating Levels of Growth Differentiation Factor 15 in Association with Metabolic Disorders in People Living with HIV Receiving Combined Antiretroviral Therapy (2022) (1)
- The cross-talk among mitochondrial activity, reactive oxygen species production and apoptosis in skeletal muscle. A role for uncoupling protein-3? (2005) (1)
- Brown adipose tissue as an endocrine organ (2018) (1)
- Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression (2022) (1)
- Differential effects of dolutegravir, bictegravir and raltegravir in adipokines and inflammation markers on human adipocytes. (2022) (1)
- Glucocorticoid gene regulation of aquaporin-7. (2020) (1)
- Targets of metabolic toxicity of HIV antiretroviral drugs: the multiple roads to lipodystrophy and metabolic syndrome. (2010) (1)
- SYNTHESIS DURING LINEZOLID-RELATED HYPERLACTATEMIA. (2006) (1)
- In Vitro Effects of Cyanidin‐3‐O‐Glucoside on Inflammatory and Insulin‐Sensitizing Genes in Human Adipocytes Exposed to Palmitic Acid (2021) (1)
- P612Involvement of the cardiomyokine FGF21 in protection against oxidative stress damage in the heart (2014) (1)
- Association of thymidylate synthase gene polymorphisms with (2011) (1)
- European Obesity Summit (EOS) – Joint Congress of EASO and IFSO-EC, Gothenburg, Sweden, June 1 – 4, 2016: Abstracts (2016) (1)
- Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model (2020) (1)
- Downregulation of peripheral lipopolysaccharide binding protein impacts on perigonadal adipose tissue only in female mice. (2022) (1)
- association with liver and adipose tissue effects -- of FGF21 in insulin-resistant mouse models Acute glucose-lowering and insulin-sensitizing action (2011) (0)
- CXCL 14 , a Brown Adipoki ne that Mediates Brown-Fatto-Macrophage Communication in Thermogenic Adaptation Graphical (2018) (0)
- Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling (2018) (0)
- Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy (2020) (0)
- Developmental and tissue-specific involvement of PPAR α in the control of mouse UCP 3 gene expression (2004) (0)
- Nutrient signalling and cardiovascular aging. Heart and Metabolism (2014) (0)
- Adipose tissue aging partially accounts for fat alterations in HIV lipodystrophy (2022) (0)
- Front Cover: Nicotinamide Protects Against Diet‐Induced Body Weight Gain, Increases Energy Expenditure, and Induces White Adipose Tissue Beiging (2021) (0)
- Brown fat. (2023) (0)
- Meteorin-like levels are associated with active brown adipose tissue in early infancy (2023) (0)
- Obesity-related SNPs and weight gain following first-line antiretroviral therapy. (2022) (0)
- Ontogeny of FGF21 in the Human: Implications for Metabolic Health (2015) (0)
- Circulating diazepam‐binding inhibitor in infancy: Relation to markers of adiposity and metabolic health (2021) (0)
- Obesity and Cardiac Microvascular Function496Roux-en-y gastric bypass surgery reverses obesity-induced vascular dysfunction by blunting jnk2-endothelial activation497Involvement of the Fgf21 system in obesity-associated cardiomyopathy498Is low ATM protein responsible for myocardial insulin resistanc (2016) (0)
- P143. Effect of Saccharomyces cerevisiae boulardii CNCM I-1079 on bile acid signalling in post-weaning piglets (2022) (0)
- Peroxisome Proliferator-Activated Receptors- (cid:1) and - (cid:2) , and cAMP-Mediated Pathways, Control Retinol-Binding Protein-4 Gene Expression in Brown Adipose Tissue (2012) (0)
- Bhlhe40 Represses PGC-1 (cid:2) Activity on Metabolic Gene Promoters in Myogenic Cells (2015) (0)
- Iodothyronine 5’-Deiodinase Activity in Brown Adipose Tissue during Perinatal Development (1990) (0)
- Uncoupling Protein mRNA Expression during the Perinatal Period of the Rat (1990) (0)
- [14C]Glucose utilization in vitro in brown adipose tissue from virgin and pregnant rats (1985) (0)
- P119Cardiac remodeling in response to cold and deacclimation: role of autophagy (2018) (0)
- Brown adipose tissue is able to secrete factors that activate fat and carbohydrate metabolism (2020) (0)
- Leptin and uncoupling proteins (UCPs) gene expression: molecular endpoints of fetal development (2001) (0)
- A novel human fetal brown stem cell functional model to study brown adipogenesis (2016) (0)
- Effect of {beta}-carotene and retinoic acid on PPAR{gamma} expression during bovine white adipose tissue differentiation in vitro. (2008) (0)
- Circulating Concentrations of Fibroblast Growth Factor 21 are Undetectable in Human Infants at Term Birth and Surge within Hours After Birth (2014) (0)
- The armadillo-repeat containing X-linked protein 3, ARMCX3, is a negative regulator of the browning of adipose tissue associated with obesity (2022) (0)
- Circulating progranulin in human infants: relation to prenatal growth and early postnatal nutrition. (2023) (0)
- Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study (2019) (0)
- P120Role of fibroblast growth factor-21 in alcoholic cardiomyopathy (2018) (0)
- Effect of β‐carotene and retinoic acid on PPARγ expression during bovine white adipose tissue differentiation in vitro. (2008) (0)
- Secondary defects of the mitochondrial respiratory chain: the examples of neuroleptic use, CO toxicity, and HIV treatment. (2005) (0)
- Blood Sampling for Arteriovenous Difference Measurements Across Interscapular Brown Adipose Tissue in Rat. (2022) (0)
- Brown Adipose Tissue in Prepubertal Children: Associations with Sex and With the Sequence of Prenatal Growth Restraint and Postnatal Catch-up (2018) (0)
- Author Correction: The relative deficit of GDF15 in adolescent girls with PCOS can be changed into an abundance that reduces liver fat (2021) (0)
- Recent advances in our understanding of brown and beige adipose tissue : the good fat that keeps you healthy (2018) (0)
- The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity (2020) (0)
- Growth differentiation factor 11 promotes progression of non-alcoholic fatty liver disease (2020) (0)
- Autophagy is Involved in Cardiac Remodeling in Response to Environmental Temperature Change (2022) (0)
- Nutrient signalling and cardiovascular aging (2014) (0)
- Circulating GDF15 concentrations in girls with low birth weight: effects of prolonged metformin treatment (2022) (0)
- Circulating Growth-and-Differentiation Factor-15 in Early Life: Relation to Prenatal and Postnatal Size (2019) (0)
- Grasa parda (2023) (0)
- FGF21, irisin and other novel players in endocrine metabolic regulation (2014) (0)
- Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis (2016) (0)
- Vazquez-Carrera Manuel (Orcid ID: 0000-0001-7138-8207) ORAL ADMINISTRATION OF A NEW HRI ACTIVATOR AS A NEW STRATEGY TO IMPROVE HIGH-FAT-DIET-INDUCED GLUCOSE INTOLERANCE, HEPATIC STEATOSIS AND HYPERTRIGLYCERIDEMIA THROUGH FGF21 (2019) (0)
- FGF15/FGF19 is involved in the development of cardiac hypertrophy (2022) (0)
- P754Involvement of the transcription factor C/EBPbeta in pregnancy-induced cardiac hypertrophy (2014) (0)
- MON-029 Polycystic Ovary Syndrome (PCOS) in Adolescent Girls:Toward a Simple On-Treatment Predictor of Post-Treatment Ovulation Rate (2020) (0)
- Current Management of Polycystic Ovary Syndrome : From Bench to Bedside Special (2018) (0)
- Brown fat resolves hepatic inflammation in obesity (2022) (0)
- Best Practice & Research Clinical Endocrinology & Metabolism (2011) (0)
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What Schools Are Affiliated With Francesc Villarroya?
Francesc Villarroya is affiliated with the following schools:
