Francesca Aloisi
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Computer Science
Francesca Aloisi's Degrees
- PhD Computer Science University of Milan
- Masters Computer Science University of Milan
- Bachelors Computer Science University of Milan
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(Suggest an Edit or Addition)Francesca Aloisi's Published Works
Published Works
- Immune function of microglia (2001) (1252)
- Astrocytes are active players in cerebral innate immunity. (2007) (1215)
- Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. (2007) (1200)
- Detection of Ectopic B‐cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis (2004) (1078)
- Lymphoid neogenesis in chronic inflammatory diseases (2006) (883)
- Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. (2011) (677)
- Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain (2007) (658)
- A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis (2010) (610)
- Selective release of glutamate from cerebellar granule cells differentiating in culture. (1982) (487)
- BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma (2005) (445)
- Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes. (2000) (422)
- Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures (1984) (409)
- Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha. (1992) (401)
- Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis (2004) (307)
- Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. (2000) (281)
- Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. (1998) (281)
- B cells and multiple sclerosis (2008) (277)
- Preferential expression and function of Toll-like receptor 3 in human astrocytes (2004) (270)
- IL-12 production by central nervous system microglia is inhibited by astrocytes. (1997) (265)
- Sex-based differences in autoimmune diseases. (2016) (229)
- Chemokines and Glial Cells: A Complex Network in the Central Nervous System (2004) (214)
- The Costimulatory Molecule B7 is Expressed on Human Microglia in Culture and in Multiple Sclerosis Acute Lesions (1995) (209)
- CD161(high)CD8+T cells bear pathogenetic potential in multiple sclerosis. (2011) (205)
- Dendritic Cells in Multiple Sclerosis Lesions: Maturation Stage, Myelin Uptake, and Interaction With Proliferating T Cells (2006) (203)
- Relationship of apolipoprotein E and age at onset to Parkinson disease neuropathology. (2006) (199)
- Epstein–Barr virus in the multiple sclerosis brain: a controversial issue—report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria (2011) (169)
- Functional Maturation of Adult Mouse Resting Microglia into an APC Is Promoted by Granulocyte-Macrophage Colony-Stimulating Factor and Interaction with Th1 Cells1 (2000) (165)
- Astrocytes Produce Dendritic Cell-Attracting Chemokines In Vitro and in Multiple Sclerosis Lesions (2005) (161)
- The role of microglia and astrocytes in CNS immune surveillance and immunopathology. (1999) (160)
- Epstein-Barr virus and multiple sclerosis: interaction with HLA (2011) (157)
- Differentiation of cerebellar bipotential glial preecurosrs into oligodendrocytes in primary culture: Development profile of surface antigens and mitotic activity (1987) (141)
- Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development (2005) (140)
- Epstein-Barr Virus Latent Infection and BAFF Expression in B Cells in the Multiple Sclerosis Brain: Implications for Viral Persistence and Intrathecal B-Cell Activation (2010) (139)
- Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions. (1998) (135)
- Opposite effects of interferon‐γ and prostaglandin E2 on tumor necrosis factor and interleukin‐10 production in microglia: A regulatory loop controlling microglia pro‐ and anti‐inflammatory activities (1999) (135)
- Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation (1999) (132)
- ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors (2005) (130)
- Astrocyte cultures from human embryonic brain: Characterization and modulation of surface molecules by inflammatory cytokines (1992) (129)
- Increased CD8+ T Cell Response to Epstein-Barr Virus Lytic Antigens in the Active Phase of Multiple Sclerosis (2013) (127)
- Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: Synergism with IL-1β and TNFα (1993) (121)
- Analysis of B7-1 and B7-2 costimulatory ligands in cultured mouse microglia: upregulation by interferon-γ and lipopolysaccharide and downregulation by interleukin-10, prostaglandin E2 and cyclic AMP-elevating agents (1997) (119)
- Epstein‐Barr virus persistence and reactivation in myasthenia gravis thymus (2009) (108)
- Human astrocytes are only partially competent antigen presenting cells. Possible implications for lesion development in multiple sclerosis. (1994) (106)
- Astrocytes are the major intracerebral source of macrophage inflammatory protein‐3α/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro (2003) (105)
- B-Cell Enrichment and Epstein-Barr Virus Infection in Inflammatory Cortical Lesions in Secondary Progressive Multiple Sclerosis (2013) (102)
- Epstein–Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis (2012) (102)
- Induction of macrophage-derived chemokine/CCL22 expression in experimental autoimmune encephalomyelitis and cultured microglia: implications for disease regulation (2002) (101)
- Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways (2010) (95)
- CD40-CD154 interaction and IFN-gamma are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells. (1999) (95)
- Functional characterization of substance P receptors on cultured human spinal cord astrocytes: Synergism of substance P with cytokines in inducing interleukin‐6 and prostaglandin E2 production (1997) (95)
- Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells. (1994) (94)
- Glia-T cell dialogue (2000) (91)
- Radioactive in situ hybridization for Epstein-Barr virus-encoded small RNA supports presence of Epstein-Barr virus in the multiple sclerosis brain. (2013) (86)
- Plasmacytoid Dendritic Cells in Multiple Sclerosis: Intracerebral Recruitment and Impaired Maturation in Response to Interferon-&bgr; (2008) (85)
- Unveiling the enigma of the CNS as a B-cell fostering environment. (2005) (82)
- Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin β receptor-Ig fusion protein (2006) (77)
- Interferon gamma gene expression in rat central nervous system glial cells. (1998) (76)
- Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look. (2010) (75)
- Lipocalin 2 is present in the EAE brain and is modulated by natalizumab (2012) (73)
- Cytokine regulation of astrocyte function: in-vitro studies using cells from the human brain (1995) (70)
- Regulation of leukemia inhibitory factor synthesis in cultured human astrocytes. (1994) (70)
- Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations. (2012) (69)
- Oligoclonal IgG band patterns in inflammatory demyelinating human and mouse diseases (2008) (68)
- Upregulated expression of interleukin-8, RANTES and chemokine receptors in human astrocytic cells infected with HIV-1. (2000) (64)
- The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis. (2011) (63)
- Establishment, characterization, and evolution of cultures enriched in type‐2 astrocytes (1988) (62)
- Antigen Presentation in the Central Nervous System (1999) (62)
- B-cell differentiation in the CNS of patients with multiple sclerosis. (2005) (62)
- Synergistic stimulation of MHC class I and IRF‐1 gene expression by IFN‐γ and TNF‐α in oligodendrocytes (1998) (55)
- Differentiation of bipotential glial precursors into oligodendrocytes is promoted by interaction with type-1 astrocytes in cerebellar cultures. (1988) (54)
- Epstein-Barr Virus-Specific CD8 T Cells Selectively Infiltrate the Brain in Multiple Sclerosis and Interact Locally with Virus-Infected Cells: Clue for a Virus-Driven Immunopathological Mechanism (2019) (51)
- Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis (2018) (50)
- Astrocytes: Emerging stars in leukodystrophy pathogenesis (2013) (50)
- Expression of TWEAK and Its Receptor Fn14 in the Multiple Sclerosis Brain: Implications for Inflammatory Tissue Injury (2008) (49)
- Migration of dendritic cells into the brain in a mouse model of prion disease (2005) (48)
- Lymphoid chemokines in chronic neuroinflammation (2008) (48)
- Developmental appearance, antigenic profile, and proliferation of glial cells of the human embryonic spinal cord: An immunocytochemical study using dissociated cultured cells (1992) (46)
- Biochemical characterization of MLC1 protein in astrocytes and its association with the dystrophin–glycoprotein complex (2008) (46)
- Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: synergism with IL-1 beta and TNF alpha. (1993) (45)
- Peripheral tissue release of interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and microinflammatory state. (2006) (44)
- Characterization of GABAergic neurons in cerebellar primary cultures and selective neurotoxic effects of a serum fraction (1985) (43)
- Developmental features of rat cerebellar neural cells cultured in a chemically defined medium (1986) (43)
- Intracerebral regulation of immune responses (2001) (41)
- Heterotypic and homotypic cellular interactions influencing the growth and differentiation of bipotential oligodendrocyte-type-2 astrocyte progenitors in culture. (1991) (41)
- Virological and molecular parameters of HIV-1 infection of human embryonic astrocytes (1998) (37)
- MLC1 trafficking and membrane expression in astrocytes: Role of caveolin-1 and phosphorylation (2010) (35)
- Targeting IL-12, the key cytokine driving Th1-mediated autoimmune diseases. (1997) (35)
- Massive intracerebral Epstein-Barr virus reactivation in lethal multiple sclerosis relapse after natalizumab withdrawal (2017) (34)
- Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis (2012) (33)
- Causes of hyperhomocysteinemia in patients with chronic kidney diseases. (2006) (30)
- Anterior tension-free repair under local anesthesia of abdominal wall hernias in continuous ambulatory peritoneal dialysis patients (2004) (30)
- The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis Pathogenesis (2021) (28)
- EEG and behavioral effects of morphine, enkephalins and derivatives administered into the lateral cerebral ventricles of rats and rabbits. (1980) (26)
- Angiotensin II Modulates the Activity of Na+,K+‐ATPase in Cultured Rat Astrocytes via the AT1 Receptor and Protein Kinase C‐δ Activation (2000) (24)
- Epstein–Barr virus nuclear antigen-1 B-cell epitopes in multiple sclerosis twins (2011) (24)
- ROR&ggr;t Expression and Lymphoid Neogenesis in the Brain of Patients with Secondary Progressive Multiple Sclerosis (2016) (23)
- Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis (2015) (22)
- Epstein-barr virus in the central nervous system and cervical lymph node of a patient with primary progressive multiple sclerosis. (2014) (19)
- Short-lived immunization site inflammation in self-limited active experimental allergic encephalomyelitis. (2000) (17)
- Administration of PLP139–151 Primes T Cells Distinct from Those Spontaneously Responsive In Vitro to This Antigen1 (2008) (17)
- Is the oligodendroglial differentiation of bipotential oligodendrocyte-type 2 astrocyte progenitors promoted by autocrine factors? (1991) (15)
- Gene transfer in astrocytes: Comparison between different delivering methods and expression of the HIV‐1 protein Nef (1999) (15)
- Establishment of a permanent rat brain‐derived glial cell line as a source of purified oligodendrocyte‐type 2 astrocyte lineage cell populations (1990) (15)
- Epstein-Barr virus-associated immune reconstitution inflammatory syndrome as possible cause of fulminant multiple sclerosis relapse after natalizumab interruption (2018) (14)
- Substrate specificity and developmental aspects of a presynaptic gaba receptor regulating glutamate release in the rat cerebellum (1983) (13)
- HIV‐1 Nef alters the expression of βII and ϵ isoforms of protein kinase c and the activation of the long terminal repeat promoter in human astrocytoma cells (1999) (11)
- Epstein‐barr virus in myasthenia gravis thymus: A matter of debate (2011) (10)
- Connecting Immune Cell Infiltration to the Multitasking Microglia Response and TNF Receptor 2 Induction in the Multiple Sclerosis Brain (2020) (7)
- Epstein-Barr virus and multiple sclerosis: supporting causality (2022) (6)
- Dendritic cells loaded with apoptotic oligodendrocytes as a source of myelin T-cell epitopes in multiple sclerosis. (2008) (6)
- Behavioral and electroencephalographic effects of chronic administration of diazepam in rats and rabbits. (1982) (5)
- Interaction between oligodendroglia and immune cells: Mitogenic effect of an oligodendrocyte precursor cell line on syngeneic T lymphocytes (1992) (5)
- Antiviral immune response in patients with multiple sclerosis, healthy siblings and twins (2010) (4)
- Glial conditioned media inhibit the proliferation of cultured rat cerebellar astrocytes (1987) (4)
- HIV-1 Nef alters the expression of betaII and epsilon isoforms of protein kinase C and the activation of the long terminal repeat promoter in human astrocytoma cells. (1999) (4)
- More on multiple sclerosis and neuromyelitis optica. (2007) (4)
- Malnutrition in peritoneal dialysis patients: causes and diagnosis. (2003) (4)
- CHAPTER 28 – Dendritic cells in the central nervous system (2001) (4)
- Central effects of dermorphin. (1982) (4)
- MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis (2022) (3)
- Immune reactivity in the central nervous system: intercellular control of the expression of major histocompatibility antigens (1990) (3)
- Human myelin basic protein specific T cell lines display differential cytotoxicity against astrocytes, but are consistently cytotoxic against monocytes (1998) (3)
- Cytokine and Growth Factor Synthesis in Human Astrocytes (1997) (2)
- Cellular interactions promoting the oligodendroglial differentiation of bipotential glial precursors in culture (1990) (2)
- More on Multiple Sclerosis and Neuromyelitis Optica. Authors' reply (2007) (2)
- Differentiation of Glial Precursors in Cerebellar Primary Cultures (1988) (2)
- Growth factors (2003) (1)
- Regulation of T cell costimulatory signals m murine CNS glia (1995) (1)
- Platelet-derived growth factor production in human astrocytes is regulated by TGF-β 1 and TNF-α (1994) (1)
- BAFF production in human brain by astrocytes: the central nervous system as a B cell fostering environment (2004) (1)
- Highlights from the Seventh International Congress of the International Society of Neuroimmunology (2005) (1)
- Antigenic and Functional Characteristics of a Bipotential Glial Progenitor Cell in Rat Cerebellar Primary Cultures (1987) (1)
- In vitro studies on the interactions between antigen-specific T line cells and CNS glial cells (1991) (1)
- Antinociceptive Action of Cholinomimetics Evaluated with the Method of the Return of Corneal Anesthesia Induced with Procaine (1981) (1)
- regulation of platelet-derived growth factor (PDGF) synthesis in human astrocytes by cytokines (1995) (1)
- Rheumatoid arthritis-etiology, pathogenesis and animal models (1)
- Cytokine production by normal human astrocytes in culture (1991) (1)
- Astrocytes are the major intracerebral source of CCL20 in mice with relapsing experimental autoimmune encephalomyelitis and in vitro (2002) (1)
- Editorial Board (2003) (0)
- TNF-α and IFN-γ-mediated signal transduction pathways: Effects on IRF-1 and MHC class I gene expression in oligodendrocytes (1997) (0)
- Reviewer Acknowledgment (1998) (0)
- ROR c t Expression and Lymphoid Neogenesis in the Brain of Patients with Secondary Progressive Multiple Sclerosis (2016) (0)
- This Antigen Spontaneously Responsive In Vitro to T Cells Distinct from Those Primes 139151 Administration of PLP (2010) (0)
- [Clinical results with a pyolytic and fibrinolytic enzyme complex used in combination with antibiotic therapy in chronic purulent bronchopulmonary infections]. (1954) (0)
- Astrocytes as Th2-promoting APC in the central nervous system☆ (1997) (0)
- Expression and regulation of T cell costimulatory signals in glial cells of the central nervous system (1996) (0)
- Ela Foundation Organization Chart Board of Trustees Scientific Committee Steering Committee Table of Contents (0)
- Regulation and chemotactic properties of astrocyte-derived macrophage inflammatory protein-3alpha/CCL20 (2002) (0)
- Multiple sclerosis and iron homeostasis (2012) (0)
- ActivationProcessing and in Th1 But Not Th2 Cell Microglia Are More Efficient Than Astrocytes in (2013) (0)
- Development of 3H-GABA uptake and evoked release in cerebellar interneuron-enriched primary cultures (1985) (0)
- Experimental autoimmune encephalomyelitis susceptibility in C57bL and sjl inbred mice: effects of early manipulations (2004) (0)
- Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis (2015) (0)
- Editorial Board (2002) (0)
- EBV as the 'gluten of MS' hypothesis: Bypassing autoimmunity. (2022) (0)
- Microglia and astrocytes as regulators of Th1 and Th2 responses (1998) (0)
- Editorial Board (2003) (0)
- Editorial Board (2003) (0)
- Distribution of Leu‐19(CD56) Natural Killer Lymphocyte Antigen in Cultured Cells from the Human Embryonic Central Nervous System a (1992) (0)
- Translational neuroimmunology: A joint meeting of the Israel Society of Neuroimmunology and the Italian Neuroimmunology Association—Conference review (2009) (0)
- A6.5 Synovial Lymphoid Structures Support Epstein-Barr Virus Persistence and Autoreactive Plasma Cell Infection in Rheumatoid Arthritis (2013) (0)
- Editorial Board (2003) (0)
- ATP-mediated activation of purinergic receptors affects oligodendrocyte progenitor cell migration and proliferation (2003) (0)
- ANTIGEN PRESENTATION IN THE CENTRAL NERVOUS SYSTEM : ROLE OF MICROGLIA ANDASTROCYTES IN THE STIMULATION OF THL AND TH2 RESPONSES (1998) (0)
- Editorial Board (2003) (0)
- Editorial Board (2003) (0)
- Epstein–Barr virus and plasmacytoid dendritic cells: A possible duet in autoimmunity (2009) (0)
- Congress Schedule (1998) (0)
- Glial cell interactions affecting oligodendrocyte development in culture (1990) (0)
- Induction of indoleamine 2,3-dioxygenase activity in human native astrocytes (1995) (0)
- Selectivity of [3H] GABA uptake and release in cells cultured from the rat cerebellum. (1984) (0)
- EXPRESSION OF ANTIGENS DEFINED BY THE MONOCLONAL ANTIBODY AT5 IN CULTURED NEURAL CELLS AND IN HUMAN BRAIN TUMORS OF GLIAL ORIGIN (1997) (0)
- Pathological relevance of meningeal B-cell follicles in secondary progressive multiple sclerosis (2006) (0)
- Antigen-dependent HLA-DR-restricted lysis of human astrocytes by CD4+ T-cell lines specific for myelin-basic protein (MBP) (1991) (0)
- Evaluation of the analgesic activity of morphine, enkephalins and their synthetic analogues. (1982) (0)
- Epstein-Barr virus-specific CD8 T cells selectively infiltrate the multiple sclerosis brain and interact locally with virus infected cells: clue for a virus-driven immunopathological mechanism response to in (2019) (0)
- Epstein-Barr virus as a cause of multiple sclerosis: opportunities for prevention and therapy (2023) (0)
- Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis (2018) (0)
- [Endothelia and surface cells of the serous membranes; histological and physiopathological study]. (1957) (0)
- Editorial Board (2002) (0)
- Tissue-resident memory T cells in the multiple sclerosis brain and their relationship to Epstein-Barr virus infected B cells (2023) (0)
- Oligodendroglia. Edited by W.T. Norton. New York: Plenum Press, 1984, pages I–XVIII, 1–351 (1986) (0)
- auses of Hyperhomocysteinemia n Patients With Chronic Kidney Diseases (2006) (0)
- Editorial Board (2002) (0)
- Acknowledgment to reviewers (1996) (0)
- Acknowledgment of Reviewers (2019) (0)
- HIV-1 infection of human embryonic astrocytes (1995) (0)
- Effect of Two Modified Met-enkephalins on the EGG and Behavior of Rats and Rabbits (1983) (0)
- Synthesis of pro-and anti-inflammatory cytokines in microglia: Regulatory role of interferon-g and prostaglandin E2 (1998) (0)
- The costimulatory molecule B7 is expressed in cultured human microglia in multiple sclerosis acute lesions (1994) (0)
- Tissue donations for multiple sclerosis research: current state and suggestions for improvement (2022) (0)
- ActivationAntigen Processing and in Th1 But Not Th2 Cell Microglia Are More Efficient Than Astrocytes in (1998) (0)
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