Francesco Di Virgilio

Francesco Di Virgilio's AcademicInfluence.com Rankings

Computer Science

#3935

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#4136

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Machine Learning

#625

World Rank

#633

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Artificial Intelligence

#825

World Rank

#839

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Database

#1181

World Rank

#1243

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Computer Science

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Francesco Di Virgilio's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice (2011) (1141)
Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. (2006) (975)
Nucleotide receptors: an emerging family of regulatory molecules in blood cells. (2001) (754)
The P2X7 Receptor: A Key Player in IL-1 Processing and Release1 (2006) (689)
The P2X7 Receptor in Infection and Inflammation (2017) (653)
Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. (1997) (630)
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells (2007) (594)
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide‐induced apoptosis: significance for the molecular mechanism of Bcl‐2 action (2001) (594)
Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase (2008) (528)
Reduced Loading of Intracellular Ca2+ Stores and Downregulation of Capacitative Ca2+Influx in Bcl-2–Overexpressing Cells (2000) (479)
Calcium and apoptosis: facts and hypotheses (2003) (466)
The P2X7 receptor: a key player in IL-1 processing and release (2007) (464)
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+. (1985) (431)
Liaisons dangereuses : P2X7 and the inflammasome (2007) (419)
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor. (1993) (375)
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment (2018) (375)
Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R (2010) (364)
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. (2016) (361)
Extracellular purines, purinergic receptors and tumor growth (2016) (355)
Mouse microglial cells express a plasma membrane pore gated by extracellular ATP. (1996) (354)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
Inhibition of Fura-2 sequestration and secretion with organic anion transport blockers. (1990) (307)
ATP-mediated cytotoxicity in microglial cells (1997) (297)
Expression of P2X7 receptor increases in vivo tumor growth. (2012) (295)
The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death (1995) (276)
Liaisons dangereuses: P2X(7) and the inflammasome. (2007) (276)
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. (2005) (272)
The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role. (1995) (268)
Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells. (2007) (258)
Cytolytic P2X purinoceptors (1998) (256)
Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. (2005) (256)
Purinergic signalling and cancer (2013) (248)
Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels (1984) (247)
Kinetics and Mechanism of ATP-Dependent IL-1β Release from Microglial Cells1 (2000) (246)
Activation of Microglia by Amyloid β Requires P2X7 Receptor Expression1 (2009) (245)
Extracellular ATP Induces a Distorted Maturation of Dendritic Cells and Inhibits Their Capacity to Initiate Th1 Responses1 (2001) (244)
p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner (2015) (244)
Inositol 1,4,5-trisphosphate induces calcium release from sarcoplasmic reticulum of skeletal muscle (1985) (237)
Alerting and tuning the immune response by extracellular nucleotides (2003) (226)
The P2X7 receptor: A main player in inflammation (2017) (220)
Purines, Purinergic Receptors, and Cancer (2012) (216)
Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor (2010) (216)
Increased Proliferation Rate of Lymphoid Cells Transfected with the P2X7 ATP Receptor* (1999) (208)
Structural and functional aspects of calcium homeostasis in eukaryotic cells. (1990) (206)
The Serotoninergic Receptors of Human Dendritic Cells: Identification and Coupling to Cytokine Release 1 (2004) (206)
P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia. (2002) (202)
An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes. (1996) (196)
Purinergic signalling in inflammation of the central nervous system (2009) (196)
Ca2+-dependent and Ca2+-independent phagocytosis in human neutrophils (1985) (196)
The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release (2000) (189)
5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. (2005) (185)
Spontaneous Cell Fusion in Macrophage Cultures Expressing High Levels of the P2Z/P2X7 Receptor (1997) (184)
Fura-2 secretion and sequestration in macrophages. A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions. (1988) (180)
Responses of mouse lymphocytes to extracellular adenosine 5'-triphosphate (ATP). Lymphocytes with cytotoxic activity are resistant to the permeabilizing effects of ATP. (1989) (178)
Extracellular adenosine triphosphate and chronic obstructive pulmonary disease. (2010) (178)
Sphingosine 1‐phosphate induces Chemotaxis of immature dendritic cells and modulates cytokine‐release in mature human dendritic cells for emergence of Th2 immune responses (2002) (177)
Ca(2+)-independent F-actin assembly and disassembly during Fc receptor- mediated phagocytosis in mouse macrophages (1991) (175)
Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells. (2000) (173)
Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levels (1988) (171)
Extracellular nucleotides mediate Ca2+ fluxes in J774 macrophages by two distinct mechanisms. (1988) (167)
Assignment of ecto‐nucleoside triphosphate diphosphohydrolase‐1/cd39 expression to microglia and vasculature of the brain (2000) (167)
Expression and function of histamine receptors in human monocyte-derived dendritic cells. (2002) (166)
Mouse dendritic cells express the P2X7 purinergic receptor: characterization and possible participation in antigen presentation. (1999) (164)
The Elusive P2X7 Macropore. (2018) (163)
Responses of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell type-dependent lysis and DNA fragmentation. (1990) (162)
Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release. (1999) (162)
A His-155 to Tyr Polymorphism Confers Gain-of-Function to the Human P2X7 Receptor of Human Leukemic Lymphocytes1 (2005) (161)
Nucleotides induce chemotaxis and actin polymerization in immature but not mature human dendritic cells via activation of pertussis toxin-sensitive P2y receptors. (2002) (160)
The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death. (1995) (156)
Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F. (1986) (156)
Purinergic signaling in the immune system (2015) (155)
The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein (2015) (154)
Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells. (1988) (152)
The P2X7 receptor sustains the growth of human neuroblastoma cells through a substance P-dependent mechanism. (2006) (149)
The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation (2010) (148)
5-Hydroxytryptamine Modulates Migration, Cytokine and Chemokine Release and T-Cell Priming Capacity of Dendritic Cells In Vitro and In Vivo (2009) (146)
Tumor promoter phorbol 12-myristate, 13-acetate inhibits phosphoinositide hydrolysis and cytosolic Ca2+ rise induced by the activation of muscarinic receptors in PC12 cells. (1985) (146)
Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. (2003) (145)
Dendritic cells exposed to extracellular adenosine triphosphate acquire the migratory properties of mature cells and show a reduced capacity to attract type 1 T lymphocytes. (2002) (144)
P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema. (2011) (144)
P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation. (2011) (144)
A role for P2X7 in microglial proliferation (2006) (143)
The Human Cathelicidin LL-37 Modulates the Activities of the P2X7 Receptor in a Structure-dependent Manner* (2008) (141)
Human CD38 ligand. A 120-KDA protein predominantly expressed on endothelial cells. (1996) (138)
P2X7: a growth-promoting receptor—implications for cancer (2009) (137)
Extracellular nucleotides and nucleosides as signalling molecules. (2018) (136)
P2 receptors: new potential players in atherosclerosis (2002) (133)
P2X7 receptor‐stimulation causes fever via PGE2 and IL‐1β release (2012) (132)
Use of luciferase probes to measure ATP in living cells and animals (2017) (130)
P2X7 receptor: Death or life? (2005) (123)
The P2X7 Receptor-Interleukin-1 Liaison (2017) (123)
Increased P2X7 receptor expression and function in thyroid papillary cancer: a new potential marker of the disease? (2008) (123)
Acute retinal ganglion cell injury caused by intraocular pressure spikes is mediated by endogenous extracellular ATP (2007) (122)
Accelerated tumor progression in mice lacking the ATP receptor P2X7. (2015) (122)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels (2021) (122)
Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema (2010) (122)
Extracellular nucleotides are potent stimulators of human hematopoietic stem cells in vitro and in vivo. (2004) (120)
The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination (2013) (119)
The P2X7 receptor is a key modulator of aerobic glycolysis (2012) (116)
Proinflammatory cytokines inhibit secretion in rat bile duct epithelium. (2001) (116)
Extracellular ATP as a possible mediator of cell-mediated cytotoxicity. (1990) (114)
Detecting adenosine triphosphate in the pericellular space (2013) (113)
Extracellular nucleotides as negative modulators of immunity. (2009) (113)
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment (2019) (113)
Apoptosis is dependent on intracellular zinc and independent of intracellular calcium in lymphocytes. (1994) (110)
Update of P2X receptor properties and their pharmacology: IUPHAR Review 30 (2020) (109)
Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection (2017) (107)
Characterization of the cytotoxic effect of extracellular ATP in J774 mouse macrophages. (1992) (107)
The Influence of Lysophosphatidic Acid on the Functions of Human Dendritic Cells (2002) (104)
Plasma membrane potential modulates chemotactic peptide-stimulated cytosolic free Ca2+ changes in human neutrophils. (1987) (103)
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors (2013) (101)
ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival (2018) (101)
Ion fluxes through the progesterone-activated channel of the sperm plasma membrane. (1993) (100)
Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors* (2003) (100)
Expression of the P2X7 Receptor Increases the Ca2+ Content of the Endoplasmic Reticulum, Activates NFATc1, and Protects from Apoptosis* (2009) (100)
ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment (2014) (99)
Extracellular ATP Exerts Opposite Effects on Activated and Regulatory CD4+ T Cells via Purinergic P2 Receptor Activation (2012) (98)
From purines to purinergic signalling: molecular functions and human diseases (2021) (97)
Intracellular calcium store depletion and acrosome reaction in human spermatozoa: role of calcium and plasma membrane potential. (2001) (97)
The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration. (2007) (96)
Extracellular ATP causes lysis of mouse thymocytes and activates a plasma membrane ion channel. (1991) (94)
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor‐bearing microparticles (2007) (90)
Agonists and antagonists acting at P2X7 receptor. (2004) (89)
The P2Y14 receptor of airway epithelial cells: coupling to intracellular Ca2+ and IL-8 secretion. (2005) (88)
Purinergic signalling, DAMPs and inflammation. (2020) (88)
Adenosine triphosphate-induced oxygen radical production and CD11b up-regulation: Ca(++) mobilization and actin reorganization in human eosinophils. (2000) (86)
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration (2011) (85)
P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability. (2006) (85)
Extracellular ATP is a trigger for the acrosome reaction in human spermatozoa. (1992) (84)
Extracellular ATP: A Feasible Target for Cancer Therapy (2020) (84)
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin‐8 from human eosinophils (2003) (81)
Voltage-dependent activation and inactivation of calcium channels in PC12 cells. Correlation with neurotransmitter release. (1987) (80)
The Antibiotic Polymyxin B Modulates P2X7 Receptor Function1 (2004) (80)
The P2Z/P2X7 receptor of microglial cells: a novel immunomodulatory receptor. (1999) (78)
P2 purinergic receptors of human eosinophils: characterization and coupling to oxygen radical production (2000) (78)
Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines. (2011) (78)
P2 receptors meet the immune system. (2001) (76)
Role of the purinergic P2Z receptor in spontaneous cell death in J774 macrophage cultures. (1996) (74)
Trophic Activity of Human P2X7 Receptor Isoforms A and B in Osteosarcoma (2014) (74)
Dysfunctional inflammasome in Schnitzler's syndrome. (2009) (73)
Purinergic modulation of mesangial extracellular matrix production: role in diabetic and other glomerular diseases. (2005) (73)
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics (2020) (72)
Dysregulation of P2X7 receptor-inflammasome axis in SAPHO syndrome: successful treatment with anakinra. (2010) (72)
The sixth sense: hematopoietic stem cells detect danger through purinergic signaling. (2012) (72)
Macrophage P2X4 receptors augment bacterial killing and protect against sepsis. (2018) (71)
Cyclic AMP inhibition of phosphoinositide turnover in human neutrophils. (1986) (69)
Neuronal death induced by endogenous extracellular ATP in retinal cholinergic neuron density control (2005) (69)
Involvement of the Purinergic P2X7 Receptor in the Formation of Multinucleated Giant Cells1 (2006) (68)
P2X(7) receptor and polykarion formation. (2000) (67)
Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent antagonist of the purinergic P2X7 receptor. (2003) (66)
IL‐18 associates to microvesicles shed from human macrophages by a LPS/TLR‐4 independent mechanism in response to P2X receptor stimulation (2012) (65)
Transient P2X7 Receptor Activation Triggers Macrophage Death Independent of Toll-like Receptors 2 and 4, Caspase-1, and Pannexin-1 Proteins* (2012) (65)
Role of P2z purinergic receptors in ATP-mediated killing of tumor necrosis factor (TNF)-sensitive and TNF-resistant L929 fibroblasts. (1992) (64)
Cell-mediated cytotoxicity: ATP as an effector and the role of target cells. (1991) (64)
Dr. Jekyll/Mr. Hyde : the dual role of extracellular ATP (2000) (64)
Enhanced P2X7 Activity in Human Fibroblasts From Diabetic Patients: A Possible Pathogenetic Mechanism for Vascular Damage in Diabetes (2004) (63)
Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity (1987) (63)
Activation of Human Alveolar Macrophages via P2 Receptors: Coupling to Intracellular Ca2+ Increases and Cytokine Secretion1 (2008) (62)
Purinergic P2Y₂ receptors promote neutrophil infiltration and hepatocyte death in mice with acute liver injury. (2012) (62)
Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis (2019) (62)
ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells (2017) (61)
Activation of site I redox-driven H+ pump by exogenous quinones in intact mitochondria. (1982) (60)
Mitochondrial DNA is not fragmented during apoptosis. (1992) (60)
Cyclic AMP inhibition of fMet-Leu-Phe-dependent metabolic responses in human neutrophils is not due to its effects on cytosolic Ca2+. (1984) (60)
Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation (2018) (59)
Muscarinic receptor-induced phosphoinositide hydrolysis at resting cytosolic Ca2+ concentration in PC12 cells (1985) (59)
Responses to extracellular ATP of lymphoblastoid cell lines from Duchenne muscular dystrophy patients. (1994) (59)
Organic-anion transport inhibitors to facilitate measurement of cytosolic free Ca2+ with fura-2. (1989) (59)
Inositol phosphate formation in fMet-Leu-Phe-stimulated human neutrophils does not require an increase in the cytosolic free Ca2+ concentration. (1985) (58)
Stimulation of purinergic receptors modulates chemokine expression in human keratinocytes. (2007) (58)
Purinergic mechanism in the immune system: A signal of danger for dendritic cells (2005) (57)
Effect of cytochalasins on cytosolic-free calcium concentration and phosphoinositide metabolism in leukocytes. (1987) (56)
High glucose modulates P2X7 receptor-mediated function in human primary fibroblasts (2000) (56)
ATP and cancer immunosurveillance (2021) (56)
P2 purinoceptors in the immune system. (1996) (56)
Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus (2013) (55)
Novel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only target (2003) (54)
Leukocyte P2 receptors: a novel target for anti-inflammatory and anti-tumor therapy. (2005) (53)
P2 receptors and immunity (2012) (53)
Purinergic signalling in the immune system. A brief update (2007) (52)
A role for calcium in Bcl-2 action? (2002) (52)
Purinergic P2X7 receptor: A pivotal role in inflammation and immunomodulation (1998) (51)
Modulation of innate and adaptive immunity by P2X ion channels. (2018) (51)
Purinoceptor function in the immune system (1996) (50)
Activation of muscarinic receptors in PC12 cells. Stimulation of Ca2+ influx and redistribution. (1986) (50)
ATP secreted by endothelial cells blocks CX₃CL 1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y₁₁ receptor activation. (2010) (50)
The P2X7 Receptor and Pannexin-1 Are Both Required for the Promotion of Multinucleated Macrophages by the Inflammatory Cytokine GM-CSF (2011) (49)
P2X receptors and inflammation. (2015) (49)
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice. (2012) (48)
New pathways for reactive oxygen species generation in inflammation and potential novel pharmacological targets. (2004) (47)
Role of P2-purinergic receptors in rat Leydig cell steroidogenesis. (1996) (45)
Dr. Jekyll/Mr. Hyde: the dual role of extracellular ATP. (2000) (45)
Characterization of volume-sensitive taurine- and Cl(-)-permeable channels. (1997) (45)
Involvement of osmo-sensitive calcium influx in human sperm activation. (1996) (45)
1513A>C polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: correlation with histological variants and clinical parameters. (2009) (45)
ATP receptors and giant cell formation (1999) (45)
Is a guanine nucleotide‐binding protein involved in excitation‐contraction coupling in skeletal muscle? (1986) (45)
H+/site, charge/site, and ATP/site ratios at coupling site III in mitochondrial electron transport. (1979) (44)
Mechanism of human sperm activation by extracellular ATP. (1996) (43)
Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel 18F-labelled PET tracer targeting P2X7 (2017) (43)
Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi. (2003) (42)
Functional characterization of P2Y and P2X receptors in human eosinophils (2001) (42)
Identification, kinetic properties and intracellular localization of the (Ca(2+)-Mg2+)-ATPase from the intracellular stores of chicken cerebellum. (1991) (42)
Purinergic mechanism in the immune system: A signal of danger for dendritic cells (2005) (42)
Extracellular ATP activates different signalling pathways in rat Sertoli cells. (1995) (41)
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells (2016) (41)
Activation of muscarinic receptors in PC12 cells. Correlation between cytosolic Ca2+ rise and phosphoinositide hydrolysis. (1986) (40)
A rationale for targeting the P2X7 receptor in Coronavirus disease 19 (2020) (40)
Tenidap enhances P2Z/P2X7 receptor signalling in macrophages. (1998) (39)
Nimodipine inhibits IL‐1β release stimulated by amyloid β from microglia (2012) (39)
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death (2016) (38)
P2×7 targeting inhibits growth of human mesothelioma (2016) (38)
Differential modulation by protein kinase C of progesterone-activated responses in human sperm. (1995) (38)
Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule (2007) (38)
P2 receptors in cancer progression and metastatic spreading. (2016) (36)
Interaction of lymphokine-activated killer cells with susceptible targets does not induce second messenger generation and cytolytic granule exocytosis (1989) (36)
Possible protective role of the 489C>T P2X7R polymorphism in Alzheimer's disease (2014) (36)
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors (2013) (35)
Role of extracellular ATP in cell-mediated cytotoxicity: a study with ATP-sensitive and ATP-resistant macrophages. (1994) (35)
Purinergic signalling in the immune system. A brief update (2007) (35)
Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI) (2015) (35)
Multiple P2X receptors are involved in the modulation of apoptosis in human mesangial cells: evidence for a role of P2X4. (2007) (34)
Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine (2019) (33)
Activation of human eosinophils via P2 receptors: novel findings and future perspectives (2006) (33)
Extracellular ATP Acting at the P2X7 Receptor Inhibits Secretion of Soluble HLA-G from Human Monocytes1 (2009) (32)
Capacitative calcium entry in rat Sertoli cells (1996) (32)
Defective P2Y purinergic receptor function: A possible novel mechanism for impaired glucose transport (2003) (29)
Role of the P2X7 receptor in tumor-associated inflammation. (2019) (29)
Why myotoxin-containing snake venoms possess powerful nucleotidases? (2013) (29)
Effects of Extracellular ATP on Mononuclear Phagocytes (1990) (28)
Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus? (2016) (28)
Resting and stimulated cytosolic free calcium levels in neutrophils from patients with Bartter's syndrome. (1987) (28)
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor. (2000) (28)
Differential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression (2020) (27)
H+/site, charge/site, and ATP/site ratios in mitochondrial electron transport. (1979) (27)
Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa (2021) (27)
Purines, purinergic receptors, and cancer. (2012) (27)
New pathways for reactive oxygen species generation in inflammation and potential novel pharmacological targets. (2004) (26)
Correlation between plasma membrane potential and second messenger generation in the promyelocytic cell line HL-60. (1990) (26)
P2X receptors and inflammation. (2015) (26)
The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease (2017) (26)
Ectonucleotidases in Acute and Chronic Inflammation (2021) (25)
Structure, function and techniques of investigation of the P2X7 receptor (P2X7R) in mammalian cells. (2019) (25)
P2Y6 Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis (2017) (24)
Novel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only target. (2003) (24)
Pharmacological blockade of the P2X7 receptor reverses retinal damage in a rat model of type 1 diabetes (2019) (23)
The P2X7 receptor of CLL lymphocytes-a molecule with a split personality (2002) (23)
Molecular machinery and signaling events in apoptosis (2001) (23)
Assessing Extracellular ATP as Danger Signal In Vivo: The pmeLuc System. (2016) (23)
Detection of Extracellular ATP in the Tumor Microenvironment, Using the pmeLUC Biosensor. (2020) (21)
Macrophages loaded with doxorubicin by ATP-mediated permeabilization: potential carriers for antitumor therapy. (1994) (21)
The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels (2019) (21)
P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors (2020) (21)
ATP as a death factor (1998) (21)
On the Role of the P2X7 Receptor in the Immune System (2001) (20)
Purinergic P2Y2 Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice with Acute Liver Injury (2012) (20)
P2X7 Receptor Expression in Patients With Serositis Related to Systemic Lupus Erythematosus (2019) (20)
Chelation of cytoplasmic Ca2+ increases plasma membrane permeability in murine macrophages. (1990) (19)
A Commentary on “PTX3 is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer” (2015) (19)
Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth (2019) (19)
Extracellular ATP, P2 receptors, and inflammation (2003) (18)
Ionophore monensin induces Na+-dependent secretion from rabbit neutrophils. requirement for intracellular Ca2+ stores. (1983) (18)
Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation. (2010) (18)
Extracellular adenosine 5'-triphosphate modulates interleukin-6 production by human thyrocytes through functional purinergic P2 receptors. (2005) (18)
P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells (2021) (17)
Astrocytes‐derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein (2021) (17)
Common Methods for Measuring Apoptotic Cell Death by Flow Cytometry (1999) (17)
Recent progress in the discovery of antagonists acting at P2X7 receptor (2005) (17)
H+/site, charge/site, and ATP/site ratios at coupling sites I and II in mitochondrial e- transport. (1979) (16)
Cytosol Mg2+ modulates Ca2+ ionophore induced secretion from rabbit neutrophils (1983) (16)
Purinergic signalling between axons and microglia. (2008) (16)
Diadenosine Homodinucleotide Products of ADP-ribosyl Cyclases Behave as Modulators of the Purinergic Receptor P2X7* (2010) (15)
P2X7 receptors and apoptosis in tuberculosis infection. (2001) (15)
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance (2021) (15)
Intracellular free calcium abnormalities in fibroblasts from non-insulin-dependent diabetic patients with and without arterial hypertension. (1997) (15)
The P2X7 Receptor: A Promising Pharmacological Target in Diabetic Retinopathy (2021) (14)
Mechanism of desensitization of neutrophil response to N-formylmethionylleucylphenylalanine by slow rate of receptor occupancy. Studies on changes in Ca2+ concentration and phosphatidylinositol turnover. (1985) (14)
The P2X7 Receptor Is Overexpressed in the Lesional Skin of Subjects Affected by Hidradenitis Suppurativa: A Preliminary Study (2019) (14)
Signalling by extracellular nucleotides in health and disease. (2022) (14)
Proapoptotic plasma membrane pore: P2X7 receptor (2001) (14)
The P2X7 Receptor 489C>T Gain of Function Polymorphism Favors HHV-6A Infection and Associates With Female Idiopathic Infertility (2020) (14)
A Defect in Glycogen Synthesis Characterizes Insulin Resistance in Hypertensive Patients With Type 2 Diabetes (2001) (13)
ATP as a death factor. (1998) (13)
P2X7 gene polymorphisms do not appear to be a susceptibility gene locus in sporadic cases of systemic lupus erythematosus. (2008) (13)
Ionic regulation of endonuclease activity in PC12 cells. (1995) (13)
Sidedness of e- donation and stoichiometry of H+ pumps at sites II + III in mitochondria from rat liver. (1981) (13)
Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes (2018) (13)
P2RX7: A receptor with a split personality in inflammation and cancer (2016) (13)
Synthesis, Biological Activity and Molecular Modeling Studies of 1,2,3,4-Tetrahydroiso-quinoline Derivatives as Conformationally Constrained Analogues of KN62, a Potent Antagonist of the P2X7-Receptor Containing a Tyrosine Moiety (2002) (12)
Fc Receptor-mediated Occurs in Macrophages at Exceedingly Low Cytosolic Ca 2+ Levels (1988) (12)
P2X receptors in cancer growth and progression. (2020) (11)
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (2020) (11)
Purinergic signalling between axons and microglia. (2006) (11)
P2RX7: A receptor with a split personality in inflammation and cancer (2016) (11)
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties (2021) (10)
Irradiation causes senescence, ATP release, and P2X7 receptor isoform switch in glioblastoma (2022) (10)
Microglia P2X4 receptors as pharmacological targets for demyelinating diseases (2018) (10)
Increased sensitivity to extracellular ATP of fibroblasts from patients affected by systemic sclerosis (2007) (10)
Synthesis, radiolabeling, and preliminary biological evaluation of [3H]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl)-piperazine, a potent antagonist radioligand for the P2X7 receptor. (2004) (10)
Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor (2020) (10)
AMP Affects Intracellular Ca2+ Signaling, Migration, Cytokine Secretion and T Cell Priming Capacity of Dendritic Cells (2012) (10)
In Vivo Detection of Extracellular Adenosine Triphosphate in a Mouse Model of Traumatic Brain Injury (2020) (9)
The mechanism for Ca2+ release induced by N‐ethylmaleimide in rat liver mitochondria (1981) (9)
Synthesis of Conformationally Constrained Analogues of KN62, a Potent Antagonist of the P2X7‐Receptor. (2000) (9)
Synergistic effect of extracellular adenosine 5'-triphosphate and tumor necrosis factor on DNA degradation. (1993) (9)
Purinergic regulation of airway inflammation. (2011) (9)
Gut microbiota and immunity in common variable immunodeficiency: crosstalk with pro-inflammatory cytokines. (2019) (8)
TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes (2019) (8)
Physiological Roles for P2 Receptors in Platelets, Visceral Smooth Muscle, and the Immune and Endocrine Systems (1998) (7)
P2X7 is a cytotoxic receptor….maybe not: implications for cancer (2020) (7)
Intracellular calcium handling by fibroblasts from non-insulin dependent diabetic patients with and without hypertension and microalbuminuria. (1996) (7)
In Vitro Cytotoxic Effects of Extracellular ATP (1992) (7)
“Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia” (2017) (7)
A3 Adenosine and P2X7 Purinergic Receptors as New Targets for an Innovative Pharmacological Therapy of Malignant Pleural Mesothelioma (2021) (6)
Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells (2021) (6)
Multiple P 2 X receptors are involved in the modulation of apoptosis in human mesangial cells : evidence for a role of P 2 X 4 (2007) (6)
Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions (2022) (6)
Extracellular ATP is increased by release of ATP-loaded microparticles triggered by nutrient deprivation (2022) (6)
Transient P 2 X 7 Receptor Activation Triggers Macrophage (2012) (6)
THE THREE PROTON PUMPS OF THE MITOCHONDRIAL RESPIRATORY CHAIN (1978) (5)
Identification of novel immunosuppressive pathways paves the way for drug discovery. (2009) (5)
Role of P2z purinergic receptors in ATP- mediated killing of TNF-sensitive and TNF-resistant L929 fibroblasts (1992) (5)
P2X7 is a cytotoxic receptor….maybe not: implications for cancer. (2020) (5)
A rationale for targeting the P2X7 receptor in Coronavirus disease 19 (Covid-19) (2020) (5)
European meeting “P2 receptors: new targets for the treatment of osteoporosis” (2011) (5)
A purinergic hypothesis for immunomodulation. (1996) (4)
Editorial overview: Purinergic P2X receptors in innate immunity and inflammation. (2019) (4)
Venous leg ulcers and apoptosis: a TIMP-3-mediated pathway? (2004) (4)
Extreme thrombocytosis in systemic juvenile idiopathic arthritis. A case report (2019) (4)
Special issue on cell and molecular biology of purinergic signalling: an introduction (2012) (4)
The P2X7 purinergic receptor in intervertebral disc degeneration (2021) (4)
Mechanisms of neutrophil and macrophage motility. (1991) (3)
Association of Hypomorphic P2X7 Receptor Genotype With Age (2020) (3)
Possible Participation in Antigen Purinergic Receptor : Characterization and 7 Mouse Dendritic Cells Express the P 2 X (1999) (3)
P2X7: a receptor with a split personality that raises new hopes for anti-cancer therapy (2021) (3)
P2 Receptors: Novel Disease Markers and Metabolic Checkpoints in Immune Cells (2022) (3)
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment (2022) (3)
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment (2018) (3)
Release from Microglial Cells b IL-1Kinetics and Mechanism of ATP-Dependent (2000) (3)
Measurement of calcium release from sarcoplasmic reticulum of skeletal muscle: effect of calcium and inositol 1,4,5-trisphosphate. (1987) (3)
Human primary fibroblasts express in vitro a purinergic P2X7 receptor coupled to ion fluxes, microvesicule formation and IL-6 release (1999) (3)
Geoffrey Burnstock - An accidental pharmacologist. (2020) (2)
Enhanced effects of insulin and angiotensin II on intracellular pH and free cytosolic calcium in fibroblasts from microalbuminuric patients with non-insulin-dependent diabetes mellitus. (1996) (2)
The Purinergic Landscape of Type 2 Diabetes Mellitus (2022) (2)
Altered Free Cytosolic Ca2+ Changes in fMet Leu Phe‐Stimulated Neutrophils from Patients with Bartter's Syndrome (1986) (2)
The Antibiotic Polymyxin B Modulates P2X (2004) (2)
Extracellular ATP: A powerful inflammatory mediator in the central nervous system (2022) (2)
Cell-Permeabilizing Properties of Extracellular ATP in Relation to Lymphocyte-Mediated Cytotoxicity (1993) (2)
Dependence of exocytosis on cytosolic Ca2+ and protein kinase c activation in human neutrophils (1984) (2)
The P2Z Receptor and Its Regulation of Macrophage Function (1995) (2)
Reply to: ‘The discovery of a new class of synaptic transmitters in smooth muscle fifty years ago and amelioration of coronary artery thrombosis’ (2013) (2)
Hemophagocytic Lymphohistiocytosis in a Patient with Relapsed Chronic Lymphocytic Leukemia Treated with Ibrutinib (2015) (2)
P2X receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (1)
Modulation of Cell Energy Metabolism by the P2X7 Receptor. (2022) (1)
Extracellular ATP activates transcription factor NFAT in mouse microglial cells (2001) (1)
SAT0006 P2x7 receptor in systemic lupus erythematosus (SLE). exploring a novel pathogenetic pathway in lupus related serositis (2018) (1)
The P2X7 receptor localizes to the mitochondria, modulates mitochondrial energy metabolism and enhances physical performance (2020) (1)
Purinergic signalling and cancer (2013) (1)
Editorial. (2021) (1)
Comment on: Monitoring Achilles enthesitis in ankylosing spondylitis during TNF-a antagonist therapy: an ultrasound study (2010) (1)
P2 Receptors of microglia: sensors for danger signals in the CNS (2008) (1)
A Commentary on “PTX3 is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer” (2015) (1)
Abstract 134: Extracellular ATP Inhibits Natural Killer Cell Recruitment in Inflamed Tissues and Protects Endothelial Cells From NK-Mediated Vascular Injury (2007) (1)
A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice (2022) (1)
Purinergic Signaling Modulates Human Bone Marrow-Derived Mesenchymal Stem Cells Function. (2009) (1)
Stimulus Activation Coupling in Neutrophils (1986) (1)
Second Messenger Generation and Secretion in PC12 Cells. Role of Ca++ and Phosphoinositide Hydrolysis (1986) (1)
Role of Plasma Membrane Potential in Granulocyte Activation (1986) (1)
C27 A novel pathway for fibroblasts activation and IL-6 release: Possible implications in atheroma formation (1999) (1)
Faculty Opinions recommendation of Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. (2012) (1)
ATP as a cytotoxic molecule (1991) (0)
Faculty of 1000 evaluation for Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics. (2018) (0)
Extracellular ATP Causes Changes in Plasma Membrane Permeability of Mouse Lymphocytes a (1990) (0)
Faculty Opinions recommendation of Fasting and cancer: molecular mechanisms and clinical application. (2018) (0)
Purinergic Signaling Differentially Modulates Normal and Leukemic Hematopoiesis. (2009) (0)
The Induction of Inhibitory Pathways in Dendritic Cells May Hamper the Efficient Activation of Anti-Leukemia T Cells within Chemotherapy-Induced Immunogenic Cell Death (2015) (0)
P2X7 dynamics in living cells. (2001) (0)
The shed P2X7 receptor is an index of adverse clinical outcome in COVID-19 patients (2023) (0)
Purinergic Signaling in Inflammation and Immunomodulation (2006) (0)
Vogels Pathways and Memory Networks Inhibitory Plasticity Balances Excitation and Inhibition in Sensory (2012) (0)
Ad-199T therapeutic activity against DENA-induced tumors in HCC mouse model. (2013) (0)
P2X receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
Abstract 3920: nfP2X7mediates survival of cancer cells in the tumor microenvironment (2018) (0)
AIRC IG 18581: The P2X7 receptor: a key determinant of cellular metabolic energetics in cancer progression. (2016) (0)
CD4 + T-Cell Functions Are Modulated by the Extracellular ATP Concentration (2011) (0)
THU0016 ALTERED EXPRESSION AND FUNCTION OF P2X7 RECEPTOR IN PATIENTSAFFECTED BY SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) (2019) (0)
Ricerca Finalizzata Ministero della Salute/Finalized Research Ministry of Health (RF-2011-02348435, 480 000 euro) Titolo/Title Investigation of the role of extracellular ATP and the P2X7 receptor in the modulation of immunosuppression within tumour microenvironment. (2014) (0)
Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (2021) (0)
Faculty Opinions recommendation of Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors. (2012) (0)
Role of P2X7 receptor in host response to melanoma (2014) (0)
Workshop 13: Regulation of Glial Cell Functions by Nucleotide Receptors (2002) (0)
Maria Teresa Miras Portugal (1948–2021): in memoriam (2021) (0)
of P2X 7 receptor-inflammasome axis in SAPHO syndrome: successful treatment with anakinra (2010) (0)
7 The Antibiotic Polymyxin B Modulates P2X (2004) (0)
Chapter 12 The Basis of Intracellular Calcium Homeostasis in Eukaryotic Cells (1996) (0)
Faculty Opinions recommendation of New role of P2X7 receptor in an Alzheimer's disease mouse model. (2018) (0)
Role of Calcium in Neutrophil Activation (2018) (0)
Role of monocytes/macrophages apoptosis during Mycobacterium tuberculosis infection (1997) (0)
Chemotherapy-Dependent ATP Release from Leukemia Dying Cells Induces Indoleamine 2,3-Dioxygenase 1 in Dendritic Cells (2016) (0)
Abstracts of the Fourth Joint German-Italian Purine Club Meeting 2011 (2011) (0)
AIRC IG 13025: The P2X7 receptor is a key switch of cancer cell glycolytic metabolism (2014) (0)
UP-REGULATION OF CALCIUM RESPONSES TO EXTRACELLULAR NUCLEOTIDES IN GAMMA INTERFERON-TREATED HUMAN MONOCYTES (1995) (0)
Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
First joint Italian-German Purine Club meeting ‘Progress in Purinergic Receptor Pharmacology and Function′ (2006) (0)
Increased sensitivity of DMD lymphoblastoid cell to low doses of X-irradiation. (1995) (0)
The P2X7-inflammasome connection: a novel pathway in autoinflammatory diseases. (2007) (0)
Faculty Opinions recommendation of Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. (2013) (0)
Cupio dissolvi: apoptosis or programmed cell death (1992) (0)
The P2X7 receptor : from ion channel to oncogene (2013) (0)
Modulation of lymphocyte and macrophage responses by extracellular ATP (1995) (0)
Faculty Opinions recommendation of ATP and potassium ions: a deadly combination for astrocytes. (2014) (0)
Extracellular ATP triggers and maintains airway inflammation in human and murine models of asthma by activating dendritic cells (2008) (0)
Apoptosis : a deadly program (1995) (0)
MECHANISM OF H+ PUMP IN RAT LIVER MITOCHONDRIA (1979) (0)
COST Action BM1406 "Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON)" (2015) (0)
P2X7 is a cytotoxic receptor….maybe not: implications for cancer (2020) (0)
Faculty Opinions recommendation of P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy. (2016) (0)
In Vitro and In Vivo Induction of Human Hematopoietic Stem Cell Migration by Extracellular UTP. (2005) (0)
P2 Purinoceptors and Regulation of the Function of Platelets, Erythrocytes and Mast Cells (1998) (0)
ROLE OF PURINERGIC RECEPTORS IN CELL DEATH AND CYTOKINE RELEASE IN THE IMMUNE SYSTEM (1996) (0)
Relationship between neurotransmitter release and cytosolic free calcium in PC12 cells (1984) (0)
P2X7 Receptor Activation By ATP As Target of Novel Therapies in Acute Myeloid Leukemia (2015) (0)
Faculty Opinions recommendation of New role of P2X7 receptor in an Alzheimer's disease mouse model. (2018) (0)
Trophic activity of human P2X7 splice variants (2011) (0)
The P2X7 receptor for extracellular nucleotides: a novel player in bone remodelling (2006) (0)
Purinergic P2 Receptor Activation T Cells via + Activated and Regulatory CD4 Extracellular ATP Exerts Opposite Effects on (2012) (0)
P2X7-dependent exchange of extracellular microparticles and mitochondria by mouse microglia (2023) (0)
Increases and Cytokine Secretion 2+ Cavia P2 Receptors: Coupling to Intracellular Activation of Human Alveolar Macrophages (2008) (0)
Faculty Opinions recommendation of Antibody to CD137 activated by extracellular adenosine triphosphate is tumor selective and broadly effective in vivo without systemic immune activation. (2020) (0)
1513A/C polymorphism in the P2X7 receptor gene in papillary thyroid cancer: correlation with the follicular variant and clinical outcome (2007) (0)
Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus Callegari , Elisa 2013-09-12 (0)
UK Purine Club 2011 Symposium (2012) (0)
P029 Inflammasome activation P2X7-dependent in Crohn's disease (2013) (0)
The Inflammation Signaling Molecule ATP Regulates Human CD4+ T Cell Functions (2010) (0)
What We Know and What We Would Like to Know About the Role of Inositol 1,4,5-Trisphosphate in Skeletal Muscle (1990) (0)
Irradiation causes senescence, ATP release, and P2X7 receptor isoform switch in glioblastoma (2022) (0)
Measurement and perturbation of intracellular calcium (1987) (0)
Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine (2019) (0)
Fetal bovine serum contains biologically available ATP. (2023) (0)
AB0595 Descriptive Analysis of A Single Center Series of 23 Patients with Positive PM-SCL Antibody (2016) (0)
Reply to Persechini et al. (1996) (0)
Cellular regulators. Part B. Calcium and lipids. (1987) (0)
human T lymphocytes An ATP-activated channel is involved in mitogenic stimulation of (2011) (0)
Purinergic Stimulation of Human Bone Marrow-Derived Mesenchymal Stem Cells Modulate Their Function and Differentiation Potential. (2010) (0)
First international workshop on nucleotides and their receptors in the immune system (2001) (0)
Studies on Voltage-Gated Calcium Channels by Means of Fluorescent [Ca2+]i Indicators (1988) (0)
The P2x7 -Hsp90 relationship: a matter of tyrosine phosphorylation? (2002) (0)
Structural and functional aspects of calcium homeostasis in eukaryotic cells (0)
Inflammatory Cytokine GM-CSF Multinucleated Macrophages by the Required for the Promotion of Receptor and Pannexin-1 Are Both 7 The P2X (2011) (0)
P.03.2 INFLAMMASOME ACTIVATION P2×7-DEPENDENT IN CROHN'S DISEASE (2013) (0)
Macrophage Targets in Inflammation: Purinergic Receptors (2003) (0)
ATP Release in the Epidermis (2010) (0)
Unorthodox localization of P2X7 receptor in subcellular compartments of skeletal system cells (2023) (0)
Faculty Opinions recommendation of Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection. (2019) (0)
Mechanisms of Tolerance Induction through T Regulatory Cells during Chemotherapy-Mediated Immunogenic Cell Death in Acute Myeloid Leukemia (2019) (0)
P2X7 receptor involvement in the pathogenesis of Hidradenitis Suppurativa (2017) (0)
AB0169 SNP (1513A>C AND 489C>T) OF P2X7 RECEPTOR IN SYSTEMIC LUPUS ERYTHEMATOSUS WITH SEROSITIS (2019) (0)
Special issue on cell and molecular biology of purinergic signalling: an introduction (2012) (0)
Nanobody-Mediated Inhibition of P2X7 on Microglia Improves Stroke Outcome (2021) (0)
from human dendritic cells -loaded microvesicles β Stimulation of P2 receptors causes release of IL-1 (2013) (0)
Editorial overview: Immunometabolism. (2021) (0)
HLA-G from Human Monocytes Receptor Inhibits Secretion of Soluble 7 Extracellular ATP Acting at the P 2 X Di (2009) (0)
Faculty Opinions recommendation of Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor. (2019) (0)
Faculty Opinions recommendation of Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity. (2020) (0)
Faculty Opinions recommendation of A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy. (2021) (0)
Editorial overview: Cancer. (2016) (0)
P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells (2021) (0)
Faculty of 1000 evaluation for ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7receptors. (2018) (0)
Expression and function of P2X7 receptor in papillary thyroid cancer: a new potential marker of the disease? (2006) (0)
How to classify the covid-19 phenotype: a response from "the first soldier in the first trench" in Lombardy, north-western Italy. (2021) (0)
High Glucose Modulates Nucleotide Receptor-Activated Responses in Human Skin Fibroblasts (1998) (0)
Faculty Opinions recommendation of ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens. (2019) (0)
Differential impact of inflammasome-induced extracellular vesicles on immune cells: key control by the functional state of the recipient cell (2021) (0)
Extracellular UTP Affects In Vitro Migration and In Vivo Homing and Engraftment of CD34+ Hematopoietic Stem Cells. (2004) (0)
F1000Prime recommendation of ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens. (2019) (0)
Cellsin the Formation of Multinucleated Giant Receptor 7 Involvement of the Purinergic P2X (2006) (0)
NLR Proteins (2016) (0)
Faculty of 1000 evaluation for Fasting and cancer: molecular mechanisms and clinical application. (2018) (0)
Editorial: Geoffrey Burnstock - An Accidental Pharmacologist (0)
P2X7 receptor polymorphism: a novel biomarker of differentiated thyroid cancer? (2007) (0)
I recettori purinergici P2 e le ectonucleotidasi: nuovi bersagli per lo sviluppo di farmaci anti-tumorali/P2 purinergic receptors and ectonucleotidases: novel targets for anti-cancer drugs (FIRB Accordi di programma n. RBAP11FXBC) (2012) (0)
Nucleotide receptors of microglial cells: novel sensors for danger signals in the central nervous system. (2001) (0)

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