Francisca Mutapi
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#224
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#1496
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Francisca Mutapi's Degrees
- Bachelors Medicine University of Zimbabwe
Why Is Francisca Mutapi Influential?
(Suggest an Edit or Addition)According to Wikipedia, Francisca Mutapi is a Professor in Global Health Infection and Immunity, co-Director of the Global Health Academy at the University of Edinburgh, and Deputy Director of the National Institute for Health Research Global Health Research Unit Tackling Infections to Benefit Africa. She is the first black woman known to have been awarded a professorship by the University of Edinburgh.
Francisca Mutapi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection (2014) (136)
- Chemotherapy accelerates the development of acquired immune responses to Schistosoma haematobium infection. (1998) (135)
- Schistosoma haematobium Treatment in 1–5 Year Old Children: Safety and Efficacy of the Antihelminthic Drug Praziquantel (2011) (118)
- A comparison of humoral responses to Schistosoma haematobium in areas with low and high levels of infection (1997) (104)
- Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. (2005) (104)
- Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children (2011) (99)
- The microbiota and helminths: sharing the same niche in the human host (2014) (90)
- The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe. (2008) (86)
- Efficacy and side effects of praziquantel treatment against Schistosoma haematobium infection among primary school children in Zimbabwe. (2008) (85)
- Knowledge attitudes and practices of grade three primary schoolchildren in relation to schistosomiasis, soil transmitted helminthiasis and malaria in Zimbabwe (2011) (84)
- Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children (2015) (84)
- Human schistosomiasis in the post mass drug administration era. (2017) (79)
- Distribution of Schistosomiasis and Soil Transmitted Helminthiasis in Zimbabwe: Towards a National Plan of Action for Control and Elimination (2014) (77)
- Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-γ, IL-4, IL-5 and IL-10 with age (2007) (70)
- Sources of heterogeneity in human monocyte subsets (2013) (67)
- Paediatric schistosomiasis: What we know and what we need to know (2018) (63)
- Acquired immune heterogeneity and its sources in human helminth infection (2010) (63)
- Age-related and infection intensity-related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population. (2008) (62)
- Integrated Analysis of Innate, Th1, Th2, Th17, and Regulatory Cytokines Identifies Changes in Immune Polarisation Following Treatment of Human Schistosomiasis (2012) (62)
- Consequences of polyparasitism on anaemia among primary school children in Zimbabwe. (2010) (60)
- Regulatory and Activated T Cells in Human Schistosoma haematobium Infections (2011) (60)
- Atopy Is Inversely Related to Schistosome Infection Intensity: A Comparative Study in Zimbabwean Villages with Distinct Levels of Schistosoma haematobium Infection (2012) (56)
- Circulating cytokine levels and antibody responses to human Schistosoma haematobium: IL-5 and IL-10 levels depend upon age and infection status (2010) (53)
- Exposure, infection and immune responses to Schistosoma haematobium in young children (2000) (52)
- Heterogeneities in anti-schistosome humoral responses following chemotherapy. (2001) (51)
- Field evaluation of a new antibody-based diagnostic for Schistosoma haematobium and S. mansoni at the point-of-care in northeast Zimbabwe (2014) (47)
- Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mouse and Human CD4 T Cells (2012) (47)
- Of Monkeys and Men: Immunomic Profiling of Sera from Humans and Non-Human Primates Resistant to Schistosomiasis Reveals Novel Potential Vaccine Candidates (2015) (43)
- Oxygen provision to fight COVID-19 in sub-Saharan Africa (2020) (43)
- Schistosome Infection Intensity Is Inversely Related to Auto-Reactive Antibody Levels (2011) (42)
- Group 2 Innate Lymphoid Cell Proportions Are Diminished in Young Helminth Infected Children and Restored by Curative Anti-helminthic Treatment (2015) (42)
- p values for pathogens: statistical inference from infectious-disease data. (2002) (42)
- Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 (2011) (41)
- Protective immunity to Schistosoma haematobium infection is primarily an anti-fecundity response stimulated by the death of adult worms (2012) (41)
- Changing Policy and Practice in the Control of Pediatric Schistosomiasis (2015) (37)
- Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria (2011) (36)
- A systematic and meta-analysis review on the diagnostic accuracy of antibodies in the serological diagnosis of COVID-19 (2020) (36)
- Infection and treatment immunizations for successful parasite vaccines (2013) (36)
- Putting the treatment of paediatric schistosomiasis into context (2017) (35)
- Chemotherapy‐induced, age‐related changes in antischistosome antibody responses (2003) (34)
- Trichuris suis ova therapy for allergic rhinitis does not affect allergen‐specific cytokine responses despite a parasite‐specific cytokine response (2012) (32)
- Comparing parasitological vs serological determination of Schistosoma haematobium infection prevalence in preschool and primary school-aged children: implications for control programmes (2014) (32)
- Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden (2006) (31)
- Association between Micronutrients (Vitamin A, D, Iron) and Schistosome-Specific Cytokine Responses in Zimbabweans Exposed to Schistosoma haematobium (2012) (31)
- Schistosomiasis therapeutics: whats in the pipeline? (2016) (29)
- Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses (2008) (29)
- Dissociation of interleukin‐4 and interleukin‐5 production following treatment for Schistosoma haematobium infection in humans (2000) (28)
- In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination (2018) (28)
- Identifying and Evaluating Field Indicators of Urogenital Schistosomiasis-Related Morbidity in Preschool-Aged Children (2015) (28)
- Review of 2022 WHO guidelines on the control and elimination of schistosomiasis. (2022) (28)
- Explaining Observed Infection and Antibody Age-Profiles in Populations with Urogenital Schistosomiasis (2011) (28)
- Dynamics of paediatric urogenital schistosome infection, morbidity and treatment: a longitudinal study among preschool children in Zimbabwe (2018) (26)
- Anti-malaria humoral responses in children exposed to Plasmodium falciparum and Schistosoma haematobium. (2007) (25)
- Predictors of COVID-19 epidemics in countries of the World Health Organization African Region (2021) (23)
- Coinfections and comorbidities in African health systems: At the interface of infectious and noninfectious diseases (2018) (22)
- Chitinase 3-Like 1 Protein Levels Are Elevated in Schistosoma haematobium Infected Children (2012) (22)
- High Seroprevalence of Enterovirus Infections in Apes and Old World Monkeys (2012) (22)
- Predicted Impact of Mass Drug Administration on the Development of Protective Immunity against Schistosoma haematobium (2014) (22)
- Proportions of CD4+ memory T cells are altered in individuals chronically infected with Schistosoma haematobium (2012) (21)
- Contrasting cellular responses in Schistosoma haematobium infected and exposed individuals from areas of high and low transmission in Zimbabwe. (2003) (21)
- Seroepidemiology of Plasmodium species infections in Zimbabwean population (2016) (20)
- The gut microbiome in the helminth infected host. (2015) (20)
- Strengthening national health research systems in the WHO African Region – progress towards universal health coverage (2019) (19)
- Efficacy of praziquantel has been maintained over four decades (from 1977 to 2018): A systematic review and meta-analysis of factors influence its efficacy (2021) (19)
- Peptidases of Trichobilharzia regenti (Schistosomatidae) and its molluscan host Radix peregra S. Lat. (Lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite. (2007) (18)
- Improving diagnosis of urogenital schistosome infection (2011) (18)
- Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models (2020) (18)
- IgE: a Key Antibody in Schistosoma Infection (2006) (18)
- Human Schistosome Infection and Allergic Sensitisation (2012) (18)
- Stochastic simulation and the detection of immunity to schistosome infections (2000) (18)
- Cytokine Responses to the Anti-schistosome Vaccine Candidate Antigen Glutathione-S-transferase Vary with Host Age and Are Boosted by Praziquantel Treatment (2014) (18)
- Efficacy of integrated school based de-worming and prompt malaria treatment on helminths -Plasmodium falciparum co-infections: A 33 months follow up study (2011) (18)
- The predicted impact of immunosuppression upon population age–intensity profiles for schistosomiasis (2008) (17)
- The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children (2020) (17)
- The helminth parasite proteome at the host-parasite interface - Informing diagnosis and control. (2015) (16)
- Group 2 ILCs: A way of enhancing immune protection against human helminths? (2017) (15)
- A Meta-Analysis of Experimental Studies of Attenuated Schistosoma mansoni Vaccines in the Mouse Model (2015) (15)
- Age-Related Patterns in Human Myeloid Dendritic Cell Populations in People Exposed to Schistosoma haematobium Infection (2012) (15)
- Down Regulation of the TCR Complex CD3ζ-Chain on CD3+ T Cells: A Potential Mechanism for Helminth-Mediated Immune Modulation (2015) (15)
- Helminth parasite proteomics: from experimental models to human infections (2012) (15)
- Cytokine responses to mitogen and Schistosoma haematobium antigens are different in children with distinct infection histories (2001) (14)
- SARS-CoV-2 Serological testing in frontline health workers in Zimbabwe (2021) (14)
- Schistosoma haematobium infection levels determine the effect of praziquantel treatment on anti-schistosome and anti-mite antibodies (2012) (14)
- Soluble CD23 Levels are Inversely Associated with Atopy and Parasite-Specific IgE Levels but Not with Polyclonal IgE Levels in People Exposed to Helminth Infection (2013) (14)
- Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children (2016) (14)
- Cluster analysis of schistosome-specific antibody responses partitions the population into distinct epidemiological groups. (2005) (13)
- Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni (2011) (13)
- Benefits of annual chemotherapeutic control of schistosomiasis on the development of protective immunity (2019) (13)
- Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection. (2010) (12)
- Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection (2013) (11)
- The anthelmintic drug praziquantel promotes human Tr1 differentiation (2019) (11)
- Africa should set its own health-research agenda (2019) (11)
- Advances in Parasite Control in Africa: From Basic Science to Translation (2012) (11)
- What are SARS-CoV-2 genomes from the WHO Africa region member states telling us? (2021) (10)
- Trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody prevalence in selected regions across Ghana (2021) (10)
- Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children (2020) (10)
- Determining the burden of fungal infections in Zimbabwe (2021) (10)
- On the calculation of intestinal schistosome infection intensity. (2003) (9)
- Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study (2021) (8)
- Efficacy and safety of single-dose 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis (2020) (8)
- The Pathogenesis of Fungal-Related Diseases and Allergies in the African Population: The State of the Evidence and Knowledge Gaps (2020) (8)
- Six rounds of annual praziquantel treatment during a national helminth control program significantly reduced schistosome infection and morbidity levels in a cohort of schoolchildren in Zimbabwe (2020) (7)
- Population level changes in schistosome‐specific antibody levels following chemotherapy (2018) (7)
- Trends of SARS-CoV-2 antibody prevalence in selected regions across Ghana (2021) (7)
- The effect of treatment on the age-antibody relationship in children infected with Schistosoma mansoni and Schistosoma haematobium. (2002) (6)
- Clinical morbidity associated with Schistosoma haematobium infection in pre‐school age children from an endemic district in Zimbabwe (2020) (6)
- Elevation of C-reactive protein, P-selectin and Resistin as potential inflammatory biomarkers of urogenital Schistosomiasis exposure in preschool children (2019) (5)
- Pre-school aged children are exposed to Schistosoma through Lake Kivu in Rwanda (2019) (5)
- Getting a GRiPP on everyday schistosomiasis: experience from Zimbabwe (2016) (5)
- Evidence of a distinct group of Black African patients with systemic lupus erythematosus (2018) (5)
- Assessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the Griffiths Scales of Child Development (2021) (5)
- Characterisation of tetraspanins from Schistosoma haematobium and evaluation of their potential as novel diagnostic markers (2022) (4)
- Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis (2021) (3)
- Universal Health Coverage in Africa: Coinfections and Comorbidities. (2018) (3)
- Investigating a strategy for quantifying schistosome infection levels in preschool-aged children using prevalence data from school-aged children (2020) (3)
- Association of Schistosoma haematobium infection morbidity and severity on co-infections in pre-school age children living in a rural endemic area in Zimbabwe (2020) (3)
- Recruiting students for the COVID-19 emergency response: lessons from eight African countries (2020) (3)
- CD16 Expression on Monocytes in Healthy Individuals but Not Schistosome-Infected Patients Is Positively Associated with Levels of Parasite-Specific IgG and IgG1 (2014) (3)
- Effect of Schistosoma haematobium infection on the cognitive functions of preschool age children and benefits of treatment from an endemic area in Zimbabwe (2022) (2)
- Stochastic simulation and the detection of immunity to helminth infections (2000) (2)
- Association of schistosomiasis and risk of prostate cancer development in residents of Murehwa rural community, Zimbabwe (2020) (2)
- Predictors of COVID-19 Epidemics in Countries of the World Health Organisation African Region (2021) (2)
- Possible association and co-existence of schistosome infection and prostate cancer: A systematic review. (2020) (1)
- Impact of parasitic infection on mental health and illness in humans in Africa: a systematic review (2022) (1)
- Pharmacogenetics of Praziquantel Metabolism: Evaluating the Cytochrome P450 Genes of Zimbabwean Patients During a Schistosomiasis Treatment (2022) (1)
- Knowledge, attitudes, practices and behaviours (KAPB) around water, sanitation and hygiene (WASH) in villagers exposed to schistosomiasis in Zimbabwe (2022) (1)
- Correction: Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children (2015) (1)
- Changes in the humoral immune responses after chemotherapy in single and co-infected individuals with Schisosoma haematobium and Plasmodium falciparum. (2010) (1)
- Systemic Sclerosis in Zimbabwe: Autoantibody Biomarkers, Clinical, and Laboratory Correlates (2021) (1)
- Fungal allergic sensitisation in young rural Zimbabwean children: gut mycobiome and seroreactivity characteristics (2021) (1)
- Multiplex peptide microarray profiling of antibody reactivity against neglected tropical diseases derived B-cell epitopes for serodiagnosis in Zimbabwe (2022) (1)
- CD 16 Expression on Monocytes in Healthy Individuals but Not Schistosome-Infected Patients Is Positively Associated with Levels of Parasite-Specific IgG and IgG 1 (2014) (1)
- Urogenital Schistosomiasis—Evidence-Based Benefits of Treatment Initiated Early During Childhood (2017) (1)
- Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: Impact on schistosome infection and cytokine levels (2022) (1)
- Paediatric Schistosomiasis: indirect, long-term impacts on health - Wellcome Trust (2017) (0)
- Edinburgh Research Explorer Distribution of schistosomiasis and soil transmitted Helminthiasis in Zimbabwe (2014) (0)
- Challenge of diagnosing acute infections in poor resource settings in Africa (2021) (0)
- Comparison of population exposure and potential cross-species transmission of echovirus 11, enterovirus 76 and 94 between apes and human populations in sub-Saharan Africa and Europe (2012) (0)
- Development of a multiplex peptide array card for early detection of acute febrile illness in Ghanaian children (2019) (0)
- The Identification and Characterization of Immunoreactive Fungal Proteins Recognized by Sera from Zimbabweans Sensitized to Fungi (2022) (0)
- Species and diagnostic approach used (excluded studies shaded). (2020) (0)
- Atopy is related to schistosome infection intensity: a comparative study in Zimbabwean villages with Schistosoma haematobium infection (2011) (0)
- Atopy is related to schistosome infection intensity (2012) (0)
- Seroepidemiology of Plasmodium species infections in Zimbabwean population (2016) (0)
- Edinburgh Explorer The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children (2020) (0)
- Peptide microarray IgM and IgG screening of pre-SARS-CoV-2 human serum samples from Zimbabwe for reactivity with peptides from all seven human coronaviruses: a cross-sectional study (2023) (0)
- Edinburgh Research Explorer Efficacy and safety of single 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children (2020) (0)
- Helicobacter pylori Infection Is Associated with the Selective Expression of SLE and Systemic Sclerosis Specific Autoantibodies in Zimbabwean Patients (2020) (0)
- Explorer Human Schistosome Infection and Allergic Sensitisation (2015) (0)
- Explorer High seroprevalence of enterovirus infections in apes and old world monkeys (2017) (0)
- Positive impact of preventative chemotherapy during a national helminth control program: Perception and KAP (2020) (0)
- Metabolomics for biomarker discovery in schistosomiasis: A systematic scoping review (2023) (0)
- The association of systemic inflammation and cognitive functions of pre-school aged children residing in a Schistosoma haematobium endemic area in Zimbabwe (2023) (0)
- Screening trematodes for novel intervention targets (2011) (0)
- Association of S. haematobium Infection Morbidity and Severity on Co-infections status in Pre-school Age Children Living in a Rural Endemic Area in Zimbabwe (2020) (0)
- Association of schistosomiasis and risk of prostate cancer development in residents of Murehwa rural community, Zimbabwe (2020) (0)
- Edinburgh Immunomics-guided antigen discovery for praziquantel-induced vaccination inurogenital human schistosomiasis (2021) (0)
- Conflicting COVID-19 excess mortality estimates (2023) (0)
- Urogenital Schistosomiasis—Evidence-Based Benefits of Treatment Initiated Early During Childhood (2017) (0)
- The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children (2020) (0)
- Explorer Proportions of CD 4 + memory T cells are altered in individuals chronically infected with Schistosoma haematobium (2017) (0)
- Ranked among the top universities in the world News Release (2017) (0)
- Intensity of infection and treatment outcomes by study for Schistosoma haematobium. (2020) (0)
- What does equitable global health research and delivery look like? Tackling Infections to Benefit Africa (TIBA) partnership as a case study (2023) (0)
- S0031182022000166jrv 1003..1018 (2022) (0)
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Francisca Mutapi is affiliated with the following schools:
