Franco Zunino
#133,833
Most Influential Person Now
Researcher
Franco Zunino's AcademicInfluence.com Rankings
Franco Zuninocomputer-science Degrees
Computer Science
#6039
World Rank
#6368
Historical Rank
Machine Learning
#1825
World Rank
#1849
Historical Rank
Artificial Intelligence
#2076
World Rank
#2111
Historical Rank
Database
#3159
World Rank
#3293
Historical Rank
Download Badge
Computer Science
Franco Zunino's Degrees
- PhD Computer Science University of California, Berkeley
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
Similar Degrees You Can Earn
Why Is Franco Zunino Influential?
(Suggest an Edit or Addition)Franco Zunino's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. (1996) (401)
- A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. (1996) (296)
- Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer (2002) (280)
- Interaction of daunomycin and its derivatives with DNA. (1972) (258)
- Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development. (1992) (230)
- SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis (2011) (211)
- Expression of γ-glutamyltransferase in cancer cells and its significance in drug resistance (2006) (208)
- Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents. (2010) (202)
- Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. (2003) (181)
- Overview of tumor cell chemoresistance mechanisms. (2005) (179)
- New Cisplatin Analogues—On the Way to Better Antitumor Agents (1987) (163)
- DNA topoisomerase II as the primary target of anti-tumor anthracyclines. (1990) (158)
- BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin. (2000) (156)
- Protective effect of reduced glutathione against cisplatin-induced renal and systemic toxicity and its influence on the therapeutic activity of the antitumor drug. (1989) (154)
- p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma. (2000) (145)
- Limestone and Silica Powder Replacements for Cement: Early-Age Performance. (2017) (141)
- A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431 (2004) (140)
- Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: relationship with DNA binding affinity and cytotoxicity. (1990) (139)
- Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression. (1992) (138)
- Intraarterial chemotherapy with polyoxyethylated castor oil free paclitaxel, incorporated in albumin nanoparticles (ABI‐007) (2001) (131)
- Interaction of some daunomycin derivatives with deoxyribonucleic acid and their biological activity. (1971) (127)
- γ-Glutamyltransferase, redox regulation and cancer drug resistance (2007) (126)
- Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expression (1996) (125)
- Development and therapeutic impact of HDAC6-selective inhibitors. (2012) (124)
- In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems (1998) (123)
- A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system. (1999) (118)
- Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma. (2004) (115)
- Impacting factors and properties of limestone calcined clay cements (LC3) (2019) (112)
- A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts (1999) (111)
- Camptothecins in clinical development (2004) (105)
- Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity. (2001) (98)
- New developments in antitumor anthracyclines. (1997) (98)
- The interaction of daunorubicin and doxorubicin with DNA and chromatin. (1980) (98)
- Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin. (2010) (97)
- REST Controls Self-Renewal and Tumorigenic Competence of Human Glioblastoma Cells (2012) (94)
- Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity. (1997) (93)
- Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines. (2001) (87)
- The influence of the filler effect on the sulfate requirement of blended cements (2019) (85)
- A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons. (1997) (85)
- A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line. (2001) (84)
- The potential of heparanase as a therapeutic target in cancer. (2014) (83)
- Ovarian cancer cisplatin-resistant cell lines: multiple changes including collateral sensitivity to Taxol. (1998) (83)
- Daunomycin (Daunorubicin) and Adriamycin and Structural Analogues: Biological Activity and Mechanism of Action (1975) (82)
- Expression of gamma-glutamyltransferase in cancer cells and its significance in drug resistance. (2006) (81)
- Role of apoptotic response in cellular resistance to cytotoxic agents. (1997) (81)
- Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair. (2003) (80)
- Changes of activity of daunorubicin, adriamycin and stereoisomers following the introduction or removal of hydroxyl groups in the amino sugar moiety. (1977) (80)
- The reaction between metakaolin and limestone and its effect in porosity refinement and mechanical properties (2021) (79)
- Relationship between activity and amino sugar stereochemistry of daunorubicin and adriamycin derivatives. (1976) (77)
- Analysis of SYT-SSX Fusion Transcripts and bcl-2 Expression and Phosphorylation Status in Synovial Sarcoma (2000) (76)
- Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180). (1996) (75)
- The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition (2010) (75)
- Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status. (2000) (74)
- Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells (2001) (74)
- Identification of the product of two oncogenic rearranged forms of the RET proto-oncogene in papillary thyroid carcinomas. (1992) (74)
- Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models. (2013) (73)
- Current status and perspectives in the development of camptothecins. (2002) (71)
- Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells. (2004) (70)
- Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells. (2006) (70)
- Topoisomerase poisoning activity of novel disaccharide anthracyclines. (1999) (70)
- Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin. (2001) (68)
- Role of the sugar moiety in the pharmacological activity of anthracyclines: development of a novel series of disaccharide analogs. (2001) (67)
- Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung. (1995) (67)
- Mechanisms of cellular resistance to camptothecins. (2006) (67)
- Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo. (2004) (66)
- The interaction of adriamycin and its β anomer with DNA (1977) (66)
- Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei. (1987) (65)
- Inhibition of transforming activity of the ret/ptc1 oncoprotein by a 2‐indolinone derivative (2000) (65)
- Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance. (1994) (63)
- A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes (2001) (63)
- RET/PTC1-driven neoplastic transformation and proinvasive phenotype of human thyrocytes involve Met induction and beta-catenin nuclear translocation. (2009) (63)
- Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors. (2009) (62)
- The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells. (1999) (62)
- Effects of the stereochemical configuration on the interaction of some daunomycin derivatives with DNA. (1976) (61)
- Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo. (1997) (61)
- Atomic force microscopy study of DNA conformation in the presence of drugs (2010) (60)
- DNA topoisomerase-trapping antitumour drugs. (1992) (60)
- gamma-Glutamyl transpeptidase catalyses the extracellular detoxification of cisplatin in a human cell line derived from the proximal convoluted tubule of the kidney. (2003) (60)
- Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells (2001) (59)
- Targeting RET for thyroid cancer therapy. (2009) (59)
- Specific inhibition of DNA‐polymerases from RNA tumor viruses by some new daunomycin derivatives (1972) (59)
- Molecular mechanisms of anthracycline activity. (2007) (58)
- Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds (2008) (57)
- Subcellular localization of the camptothecin analogues, topotecan and gimatecan. (2004) (57)
- A novel taxane with improved tolerability and therapeutic activity in a panel of human tumor xenografts. (1999) (57)
- Photodynamic therapy by topical meso-tetraphenylporphinesulfonate tetrasodium salt administration in superficial basal cell carcinomas. (1990) (57)
- Gimatecan, a novel camptothecin with a promising preclinical profile (2004) (56)
- Novel 7-substituted camptothecins with potent antitumor activity. (2000) (56)
- Decreased drug accumulation and increased tolerance to DNA damage in tumor cells with a low level of cisplatin resistance. (1998) (55)
- Strategies to improve the efficacy of platinum compounds. (2009) (55)
- Pre-clinical and clinical significance of heparanase in Ewing’s sarcoma (2011) (54)
- Comparison of dna cleavage induced by etoposide and doxorubicin in two human small‐cell lung cancer lines with different sensitivities to topoisomerase ii inhibitors (1990) (53)
- Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs (2010) (53)
- High-dose cisplatin and cyclophosphamide with glutathione in the treatment of advanced ovarian cancer. (1993) (52)
- Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid (2004) (52)
- Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage. (1994) (52)
- Inactivation of Ret/Ptc1 oncoprotein and inhibition of papillary thyroid carcinoma cell proliferation by indolinone RPI-1 (2003) (51)
- Factors influencing the sulfate balance in pure phase C3S/C3A systems (2020) (51)
- Comparison of doxorubicin‐induced DNA damage in doxorubicin‐sensitive and ‐resistant P388 murine leukemia cells (1986) (50)
- ABC transporters as potential targets for modulation of drug resistance. (2009) (50)
- Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo (2011) (50)
- Mechanism of action of DNA topoisomerase inhibitors (1995) (50)
- Protective Effect of Reduced Glutathione against CIS-Dichlorodiammine Platinum (II)–Induced Nephrotoxicity and Lethal Toxicity (1983) (50)
- Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors. (2011) (50)
- A Preliminary Clinical Experience with Reduced Glutathione as Protector against Cisplatin-Toxicity (1987) (49)
- A novel atypical retinoid endowed with proapoptotic and antitumor activity. (2003) (49)
- Anti‐tumor activity of daunorubicin linked to poly‐L‐aspartic acid (1982) (49)
- Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. (2001) (49)
- MRP gene overexpression in a human doxorubicin‐resistant SCLC cell line: Alterations in cellular pharmacokinetics and in pattern of cross‐resistance (1995) (48)
- Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells. (1989) (48)
- Similar sequence specificity of mitoxantrone and VM-26 stimulation of in vitro DNA cleavage by mammalian DNA topoisomerase II. (1993) (48)
- A comparison of the effects of daunomycin and adriamycin on various DNA polymerases. (1975) (48)
- Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells (2003) (48)
- Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction. (2006) (47)
- Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors (2008) (47)
- The inhibition of RNA polymerase by daunomycin. (1974) (47)
- Synthesis and cytotoxic activity of polyamine analogues of camptothecin. (2006) (47)
- Evaluating the hydration of high volume fly ash mixtures using chemically inert fillers (2018) (46)
- Role of apoptosis and apoptosis-related proteins in the cisplatin-resistant phenotype of human tumor cell lines (2004) (46)
- Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts. (2003) (45)
- Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairment. (2007) (45)
- A preoperative single course of high-dose cisplatin and bleomycin with glutathione protection in bulky stage IB/II carcinoma of the cervix. (1992) (44)
- Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1 (2006) (44)
- Gamma-glutamyltransferase, redox regulation and cancer drug resistance. (2007) (44)
- Interaction of ionizing radiation with topotecan in two human tumor cell lines (1996) (44)
- Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells. (1990) (44)
- Decoupling the physical and chemical effects of supplementary cementitious materials on strength and permeability: A multi-level approach (2016) (44)
- Poly(carboxylic acid) polymers as carriers for anthracyclines (1989) (43)
- Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment. (2010) (43)
- Mode of tilorone hydrochloride interaction to DNA and polydeoxyribonucleotides (1972) (43)
- Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts. (2002) (43)
- Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents. (2000) (43)
- Effect of a Novel Vacuolar-H+-ATPase Inhibitor on Cell and Tumor Response to Camptothecins (2006) (43)
- Clavilactones, a novel class of tyrosine kinase inhibitors of fungal origin. (2000) (43)
- Yeast mutants as a model system for identification of determinants of chemosensitivity. (2000) (42)
- Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases (2016) (42)
- 7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors. (2014) (42)
- Efficacy and safety of high-dose cisplatin and cyclophosphamide with glutathione protection in the treatment of bulky advanced epithelial ovarian cancer (2004) (42)
- Oral efficacy and bioavailability of a novel taxane. (2000) (41)
- Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1. (2006) (41)
- Synthesis and cytotoxic activity of substituted luotonin A derivatives. (2004) (40)
- Emergence of p53 mutant cisplatin-resistant ovarian carcinoma cells following drug exposure: spontaneously mutant selection. (1999) (40)
- Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents. (2013) (40)
- Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response (2002) (39)
- Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery. (2012) (39)
- Biodistribution of haematoporphyrin analogues in a lung carcinoma model. (1995) (39)
- Dose Intensification of Platinum Compounds with Glutathione Protection as Induction Chemotherapy for Advanced Ovarian Carcinoma (1999) (39)
- Comparison of antitumor effects of daunorubicin covalently linked to poly-L-amino acid carriers. (1984) (39)
- Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer. (2002) (38)
- Clay calcination technology: state-of-the-art review by the RILEM TC 282-CCL (2021) (38)
- Antimetastatic Effect of a Small-Molecule Vacuolar H+-ATPase Inhibitor in in Vitro and in Vivo Preclinical Studies (2008) (37)
- Role of Bcl-2 and its post-transcriptional modification in response to antitumor therapy. (2001) (37)
- Template specific inhibition of DNA polymerases from RNA tumor viruses by distamycin A and its structural analogues (1972) (37)
- Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. (2008) (37)
- Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types. (1994) (37)
- Poly-L-aspartic acid as a carrier for doxorubicin: a comparative in vivo study of free and polymer-bound drug. (1985) (37)
- Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts. (1998) (37)
- Bis‐deae‐fluorenone: A specific inhibitor of DNA polymerases from RNA tumor viruses (1972) (37)
- Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition. (2012) (36)
- Relevance of extracellular and intracellular interactions of camptothecins as determinants of antitumor activity. (2007) (35)
- Low-temperature curing strength enhancement in cement-based materials containing limestone powder (2017) (35)
- Single-strand DNA breaks induced by chromophore-modified anthracyclines in P388 leukemia cells. (1986) (35)
- Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity. (2005) (35)
- Electron Microscopy Analysis of Early Localization of Cisplatin in Ovarian Carcinoma Cells (2002) (35)
- Recycling of hydrated cement pastes by synthesis of α′H-C2S (2017) (35)
- Base sequence determinants of amonafide stimulation of topoisomerase II DNA cleavage. (1995) (34)
- DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents (2011) (34)
- The cell‐specific anti‐proliferative effect of reduced glutathione is mediated by γ‐glutamyl transpeptidase‐dependent extracellular pro‐oxidant reactions (1997) (34)
- Perspectives in the development of hybrid bifunctional antitumour agents. (2015) (34)
- Comparison of biochemical and biological methods in the evaluation of new anthracycline drugs. (1978) (34)
- Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones. (2008) (34)
- Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety. (1995) (34)
- Antitumor complexes of platinum with carrier molecules. 2 [1]. Mixed complexes of amino acids and tert-butylamine (1984) (33)
- The interaction of daunomycin with polydeoxynucleotides. (1978) (33)
- Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors. (2010) (33)
- Unique sequence specificity of topoisomerase II DNA cleavage stimulation and DNA binding mode of streptonigrin. (1994) (33)
- Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells. (2014) (33)
- Successful local regional therapy with topotecan of intraperitoneally growing human ovarian carcinoma xenografts. (1995) (32)
- Configurational requirements of the sugar moiety for the pharmacological activity of anthracycline disaccharides. (1999) (31)
- The role of topoisomerase II in drug resistance. (1991) (31)
- Thermo-mechanical assessment of concrete microcracking damage due to early-age temperature rise (2015) (31)
- Sensitization of tumor cells by targeting histone deacetylases. (2012) (31)
- Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response. (2005) (31)
- Studies on the mode of interaction of daunomycin with DNA (1971) (31)
- Influence of tilorone hydrochloride on the secondary structure and template activity of DNA (1972) (31)
- Mapping Drug Interactions at the Covalent Topoisomerase II-DNA Complex by Bisantrene/Amsacrine Congeners* (1998) (31)
- Effect of glutathione and N-acetylcysteine on in vitro and in vivo cardiac toxicity of doxorubicin. (1990) (31)
- Efficacy of the Novel Camptothecin Gimatecan against Orthotopic and Metastatic Human Tumor Xenograft Models (2004) (31)
- Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968 (2008) (31)
- Position-specific effects of base mismatch on mammalian topoisomerase II DNA cleaving activity. (1996) (31)
- Ascites Regression and Survival Increase in Mice Bearing Advanced-stage Human Ovarian Carcinomas and Repeatedly Treated Intraperitoneally With CpG-ODN (2010) (30)
- Molecular structural effects involved in the interaction of anthracyclines with DNA. (1979) (30)
- Efficacy and toxicity profile of oral topotecan in a panel of human tumour xenografts. (2000) (30)
- Molecular mechanisms of resistance to taxanes and therapeutic implications. (1999) (30)
- Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects. (1993) (30)
- The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects. (2012) (29)
- Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies. (1997) (29)
- Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models. (2007) (29)
- Glutathione and detoxification. (1990) (29)
- Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors. (2012) (29)
- Cellular response to oxidative stress and ascorbic acid in melanoma cells overexpressing gamma-glutamyltransferase. (2008) (29)
- Improved Apoptotic Cell Death in Drug-Resistant Non–Small-Cell Lung Cancer Cells by Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Based Treatment (2014) (28)
- Sensitization of ovarian carcinoma cells to the atypical retinoid ST1926 by the histone deacetylase inhibitor, RC307: enhanced DNA damage response (2009) (28)
- Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants. (1998) (28)
- Reducing setting time of blended cement paste containing high-SO3 fly ash (HSFA) using chemical/physical accelerators and by fly ash pre-washing. (2018) (28)
- Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins. (2013) (28)
- Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility. (1996) (28)
- Irreversible and reversible topoisomerase II DNA cleavage stimulated by clerocidin: sequence specificity and structural drug determinants. (1997) (27)
- Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839. (2005) (27)
- A Feasibility Study of High-Dose Cisplatin and 5-Fluorouracil with Glutathione Protection in the Treatment of Advanced Colorectal Cancer (1990) (27)
- 8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation. (1999) (27)
- Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin. (2001) (27)
- Short communicationThe status of the brown bear (Ursus arctos) in Abruzzo national park, Italy, 1971: undefined (1972) (26)
- ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968. (2010) (26)
- p53 in drug resistance in ovarian cancer (1997) (26)
- Effects of 5-FU and cis-DDP Combination on Human Colorectal Tumor Xenografts (1989) (26)
- Endogenous Oxidative Stress Induces Distinct Redox Forms of Tumor Necrosis Factor Receptor‐1 in Melanoma Cells (2004) (25)
- Metabolic Approach to the Enhancement of Antitumor Effect of Chemotherapy: a Key Role of Acetyl-l-Carnitine (2010) (25)
- Eradication of Ovarian Tumor Xenografts by Locoregional Administration of Targeted Immunotherapy (2008) (25)
- Human DNA topoisomerase IIalpha-dependent DNA cleavage and yeast cell killing by anthracycline analogues. (1998) (25)
- Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus. (2006) (25)
- Differential efficacy of flavone acetic against liver versus lung metastases in a human tumour xenograft. (1991) (25)
- Erratum: A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system (Molecular Pharmacology (1999) 55 (528-534)) (1999) (25)
- Validation of double gradient denaturing gradient gel electrophoresis through multigenic retrospective analysis. (1999) (24)
- Bcl-2 phosphorylation in a human breast carcinoma xenograft: a common event in response to effective DNA-damaging drugs. (2000) (24)
- Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series. (2007) (24)
- c-MYC G-quadruplex binding by the RNA polymerase I inhibitor BMH-21 and analogues revealed by a combined NMR and biochemical Approach. (2018) (24)
- The impact of calcite impurities in clays containing kaolinite on their reactivity in cement after calcination (2020) (24)
- Detection of p53 point mutations by double‐gradient, denaturing gradient gel electrophoresis (1997) (24)
- The role of glutathione in combination with cisplatin in the treatment of ovarian cancer. (1991) (24)
- Effect of protein kinase C inhibitors on invasiveness of human melanoma clones expressing different levels of protein kinase C isoenzymes (1994) (24)
- Assessing the effect of alkanolamine grinding aids in limestone calcined clay cements hydration (2021) (24)
- Effect of the methylation of aglycone hydroxyl groups on the biological and biochemical properties of daunorubicin. (1981) (23)
- Topical Administration of Tetrasodium-Mesotetraphenyl-Porphinesulfonate (TPPS) and Red Light Irradiation for the Treatment of Superficial Neoplastic Lesions (1987) (23)
- DNA topoisomerase II poisons and inhibitors. (1997) (23)
- Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides. (2011) (23)
- Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides. (2008) (23)
- Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity. (1986) (23)
- DNA topoisomerase inhibitors. (1993) (23)
- Extra‐cellular thiol metabolism in clones of human metastatic melanoma with different gamma‐glutamyl transpeptidase expression: Implications for cell response to platinum‐based drugs (2002) (23)
- Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts. (1998) (23)
- Base mutation analysis of topoisomerase II-idarubicin-DNA ternary complex formation. Evidence for enzyme subunit cooperativity in DNA cleavage. (1994) (23)
- Studies on the interaction of distamycin A and its derivatives with DNA. (1972) (22)
- Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts. (2005) (22)
- A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line. (2001) (22)
- Efficacy of lonidamine combined with different DNA-damaging agents in the treatment of the MX-1 tumor xenograft (1996) (22)
- Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors. (2008) (22)
- Characterization of an established human, malignant, glioblastoma cell line (GBM) and its response to conventional drugs (2005) (22)
- A methodology for assessing the chemical and physical potential of industrially sourced rice husk ash on strength development and early-age hydration of cement paste (2017) (22)
- Global gene expression of fission yeast in response to cisplatin (2004) (22)
- Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin. (2004) (22)
- Formation, resealing and persistence of DNA breaks produced by 4-demethoxydaunorubicin in P388 leukemia cells. (1989) (21)
- Sequence dependence of the antitumor and toxic effects of 5-fluorouracil and cis-diamminedichloroplatinum combination on primary colon tumors in mice (2004) (21)
- Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models. (2003) (21)
- Peripheral Neurotoxicity following High-Dose Cisplatin with Glutathione: Clinical and Neurophysiological Assessment (1992) (21)
- Gene expression of DNA topoisomerases I, IIα and IIβ and response to cisplatin‐based chemotherapy in advanced ovarian carcinoma (1996) (21)
- Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor. (2015) (21)
- Pleiotropic antitumor effects of the pan‐HDAC inhibitor ITF2357 against c‐Myc‐overexpressing human B‐cell non‐Hodgkin lymphomas (2014) (20)
- Histone deacetylase and microtubules as targets for the synthesis of releasable conjugate compounds. (2009) (20)
- Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors. (2014) (20)
- Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma. (2010) (20)
- IDN 5390: an oral taxane candidate for protracted treatment schedules (2003) (20)
- Biologic Activity of Daunorubicin Linked to Proteins via the Methylketone Side Chain (1981) (20)
- Increasing the kaolinite content of raw clays using particle classification techniques for use as supplementary cementitious materials (2020) (20)
- Steric influence of the orientation of the primary amino group at position 3 of the sugar moiety of anthracycline antibiotics in DNA binding properties (1977) (19)
- Apoptosis induced by extracellular glutathione is mediated by H2O2 production and DNA damage (2000) (19)
- Novel bis-platinum complexes endowed with an improved pharmacological profile. (2010) (19)
- Camptothecin‐7‐yl‐methanthiole: Semisynthesis and Biological Evaluation (2012) (19)
- Mutagenic and cytotoxic activity of doxorubicin and daunorubicin derivatives on prokaryotic and eukaryotic cells. (1984) (19)
- Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid. (2009) (19)
- Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft (2004) (19)
- Short Synthesis of Cytotoxic 4‐Arylcoumarins (2006) (18)
- DNA-interactive anticancer aza-anthrapyrazoles: biophysical and biochemical studies relevant to the mechanism of action. (2001) (18)
- Characterization of a topoisomerase II gene rearrangement in a human small-cell lung cancer cell line. (1992) (18)
- Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity. (2016) (18)
- Synthesis, Modelling, and Antimitotic Properties of Tricyclic Systems Characterised by a 2‐(5‐Phenyl‐1H‐pyrrol‐3‐yl)‐1,3,4‐oxadiazole Moiety (2009) (18)
- Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones. (2007) (18)
- Spontaneous lung metastases in a human lung tumor xenograft: A new experimental model (2005) (17)
- Fas/CD95-mediated apoptosis in human glioblastoma cells: a target for sensitisation to topoisomerase I inhibitors. (2002) (17)
- Modulation of cell sensitivity to antitumor agents by targeting survival pathways. (2010) (17)
- Role of c-myc protein in hormone refractory prostate carcinoma: cellular response to paclitaxel. (2004) (17)
- Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins. (2009) (17)
- Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug. (1987) (17)
- A novel taxane active against an orthotopically growing human glioma xenograft (2001) (17)
- Biological Effects of a New Vacuolar‐H,+‐ATPase Inhibitor in Colon Carcinoma Cell Lines (2009) (17)
- Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968. (2008) (17)
- Chemical vs. Physical Acceleration of Cement Hydration. (2016) (16)
- Microenvironment modulation and enhancement of antilymphoma therapy by the heparanase inhibitor roneparstat (2018) (16)
- Perspectives in camptothecin development (2002) (16)
- Gamma-glutamyltranspeptidase activity in human ovarian carcinoma. (1996) (16)
- Molecular alterations of cells resistant to platinum drugs: role of PKCalpha. (2006) (16)
- A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells. (2008) (15)
- A feasibility study of cisplatin administration with low-volume hydration and glutathione protection in the treatment of ovarian carcinoma. (1991) (15)
- Synthesis and cytotoxic activity of new 9-substituted camptothecins. (2008) (15)
- Antitumor complexes of platinum with carrier molecules. I. Sulfadiazine derivatives of platinum(II) (1983) (15)
- Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models. (2005) (15)
- Single‐strand conformation polymorphism for p53 mutation by a combination of neutral pH buffer and temperature gradient in capillary electrophoresis (2002) (15)
- Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors. (2008) (15)
- In vitro PHOTOSENSITIZING PROPERTIES OF RHODAMINE 123 ON DIFFERENT HUMAN TUMOR CELL LINES (1988) (15)
- A study on the possible involvement of nonlinear mechanism of light absorption by HpD with Nd: YAG laser (1986) (15)
- High strength lightweight concrete (HSLC): Challenges when moving from the laboratory to the field (2014) (15)
- Microstructural developments of limestone calcined clay cement (LC3) pastes after long-term (3 years) hydration (2022) (15)
- P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines. (1989) (14)
- Effects of base mutations on topoisomerase II DNA cleavage stimulated by mAMSA in short DNA oligomers. (1993) (14)
- Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring. (2006) (14)
- The role of the glutathione-dependent system in tumor sensitivity to cisplatin: a study of human tumor xenografts. (1995) (14)
- Synthesis and antitumor activity of a platinum (II)-doxorubicin complex (2004) (14)
- A comparative study of cellular and molecular pharmacology of doxorubicin and MEN 10755, a disaccharide analogue. (2001) (14)
- Stability of hemicarbonate under cement paste-like conditions (2022) (14)
- Sulfonates-PMMA nanoparticles conjugates: a versatile system for multimodal application. (2012) (14)
- Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells. (2011) (14)
- New macrocyclic analogs of the natural histone deacetylase inhibitor FK228; design, synthesis and preliminary biological evaluation. (2015) (14)
- Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation. (1996) (14)
- Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41 (2019) (14)
- Physicochemical properties, cytotoxic activity and topoisomerase II inhibition of 2,3-diaza-anthracenediones. (1997) (13)
- A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin. (2005) (13)
- Relationships among tumor responsiveness, cell sensitivity, doxorubicin cellular pharmacokinetics and drug‐induced DNA alterations in two human small‐cell lung cancer xenografts (1990) (13)
- Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice. (2001) (13)
- Small molecules targeting p53 to improve antitumor therapy. (2008) (13)
- Doxifluridine in colorectal cancer patients resistant to 5-fluorouracil (5-FU) containing regimens. (1997) (13)
- Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells. (2006) (13)
- Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors. (2015) (12)
- Antitumor Efficacy of Trastuzumab in Nude Mice Orthotopically Xenografted With Human Pancreatic Tumor Cells Expressing Low Levels of HER-2/neu (2008) (12)
- Endoscopic HpD-Laser Photoradiation Therapy (PRT) of Cancer (1984) (12)
- Novel Cytotoxic Oxopyridoindolizines: iso-Propyl-7,8,9-tri-chloro-6,7,8,9-tetrahydro-5-oxopyrido[2,3-a]-indolizine-10-carboxylates (OPIC) (2002) (12)
- Color control in industrial clay calcination (2020) (12)
- Effect of modulation of protein kinase C activity on cisplatin cytotoxicity in cisplatin-resistant and cisplatin-sensitive human osteosarcoma cells. (1993) (12)
- A Novel 9-Aza-Anthrapyrazole Effective against Human Prostatic Carcinoma Xenografts (2001) (12)
- Lack of effect of glutathione depletion on cytotoxicity, mutagenicity and DNA damage produced by doxorubicin in cultured cells. (1986) (12)
- Single‐strand conformation polymorphism analysis by capillary zone electrophoresis in neutral pH buffer (2000) (12)
- Cooperation between p53 and p73 in cisplatin-induced apoptosis in ovarian carcinoma cells. (2008) (12)
- Protein kinase C activation by anthracyclines in swiss 3T3 cells (1991) (11)
- Antitumor complexes of platinum with carrier molecules. 3. Cytotoxicity of some platinum amino acid complexes against cisplatin-sensitive and resistant L1210 leukemia cells (1986) (11)
- Synthesis and biological evaluation of pyrroloiminoquinone derivatives. (2008) (11)
- Hyperthermal Effects in Phototherapy with Hematoporphyrin Derivative Sensitization (1984) (11)
- A doxorubicin-Pt(II) complex. Chemistry and antitumor activity (1987) (11)
- Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft (2008) (11)
- Prevention of doxorubicin-induced cardiomyopathy by reduced glutathione (2004) (10)
- Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids. (2007) (10)
- Effect of tumor necrosis factor on human tumor cell lines sensitive and resistant to cytotoxic drugs, and its interaction with chemotherapeutic agents. (1990) (10)
- The interaction of natural tetra-azacyclopentazulene dyes with DNA and their effects on the DNA and RNA polymerase reactions. (1975) (10)
- Effectiveness of tetra-ethyl-ortho-silicate (TEOS) consolidation of fired-clay bricks manufactured with different calcination temperatures (2016) (10)
- Malignant transformation of host cells by a human small cell lung cancer xenografted into nude mice. (1989) (10)
- Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting. (2009) (10)
- Synthesis and evaluation of biological activity of binuclear cisplatin analogues with polyoxypropylene-α,ω-diamines as the bridging groups (1989) (10)
- E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation. (2008) (10)
- Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison. (2009) (10)
- The interaction of the beta-anomer of doxorubicin with B and Z DNA. (1986) (10)
- A study of cross‐resistance pattern and expression of molecular markers of multidrug resistance in a human small‐cell lung‐cancer cell line selected with doxorubicin (1993) (9)
- RET/PTC Oncoproteins: Molecular Targets of New Drugs (2003) (9)
- Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents (2017) (9)
- Cellular and Pharmacological Bases of the Antitumor Activity of a Novel Adamantyl Retinoid, ST1926 (2004) (9)
- Influence of some chromophore substituents on the intercalation of anthracycline antibiotics into DNA (1982) (9)
- Characterization of nanofilled epoxy varnish subjected to surface partial discharges (2007) (8)
- Synthetic retinoids as potential antitumour agents (2005) (8)
- The Effect of Limestone on the Performance of Ternary Blended Cement LC3: Limestone, Calcined Clays and Cement (2018) (8)
- Synergistic Antitumor Activity of Cetuximab and Namitecan in Human Squamous Cell Carcinoma Models Relies on Cooperative Inhibition of EGFR Expression and Depends on High EGFR Gene Copy Number (2013) (8)
- A Clinical Study of Reduced Glutathione as a Protective Agent Against Cisplatin-Induced Toxicity (1988) (8)
- Secondary mould metabolites. Part 59. Sesquiterpene illudanes: semi-synthesis of new illudins, structures and biological activity (2001) (8)
- Remarkable antitumor activity of 5'-deoxy-5-fluorouridine in human colorectal tumor xenografts. (1994) (8)
- New Cisplatin Analogues ‐ On the Way to Better Antitumor Agents (1987) (8)
- Comparative distribution of free doxorubicin and poly-L-aspartic acid linked doxorubicin in MS-2 sarcoma bearing mice. (1986) (8)
- The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates. (2008) (8)
- Insights on the role of alumina content and the filler effect on the sulfate requirement of PC and blended cements (2022) (8)
- Gene expression profiles in the cellular response to a multinuclear platinum complexe (2004) (7)
- A cell and mechanism-based approach for the selection of EGF receptor inhibitors. (1997) (7)
- Gene expression of DNA topoisomerases I, II alpha and II beta and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. (1996) (7)
- The relationship of chemical structure to cytostatic activity of some daunomycin derivatives (1972) (7)
- A Differential Interaction of Doxorubicin and Daunorubicin with Human Serum Proteins (1981) (7)
- DNA topoisomerase inhibitors. (1996) (7)
- Laser oncology in Italy: experimental research and clinical applications at the National Cancer Institute, Milan (1983) (7)
- Study of Irradiation Parameters in HpD Phototherapy of MS-2 Tumor Model (1984) (6)
- Properties and occurrence of clay resources for use as supplementary cementitious materials: a paper of RILEM TC 282-CCL (2022) (6)
- Purification and partial characterization of a daunorubicin-binding protein from rat liver. (1983) (6)
- Biophysical and biological evaluation of porphyrin-bisacridine conjugates. (1996) (6)
- Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells. (2012) (6)
- Structure–Activity Relationship Study of 16 a‐Thiocamptothecins: an Integrated In Vitro and In Silico Approach (2010) (6)
- Modulation of melphalan cytotoxic activity in human melanoma cell lines. (1996) (6)
- Synthesis, biological and biochemical properties of new anthracyclines modified in the aminosugar moiety (2004) (6)
- Effectiveness of Laser Photoradiation Therapy following Hematoporphyrin Derivative Administration in the Experimental MS-2 Tumor Model (1983) (6)
- Structural Requirements for DNA Topoisomerase II Inhibition by Anthracyclines (1990) (6)
- p53 Gene Status and Response to Topotecan-Containing Chemotherapy in Advanced Ovarian Carcinoma (2005) (6)
- Fluorinated anthracyclines: Synthesis and biological activity (1990) (6)
- Dilemma of the Abruzzo Bears (1981) (6)
- Improvement of Therapeutic Index of Low‐Dose Topotecan Delivered per os (2000) (6)
- Induction of differentiation of Friend murine erythroleukemia cells by poly-L-lysine and daunorubicin-poly-L-lysine conjugate. (1986) (6)
- Proteomic analysis of cellular response to novel proapoptotic agents related to atypical retinoids in human IGROV-1 ovarian carcinoma cells. (2011) (5)
- Effect of Paclitaxel on Intracellular Localization of c‐Myc and P‐c‐Myc in Prostate Carcinoma Cell Lines (2007) (5)
- Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity. (1995) (5)
- Protein Kinase C Activation and Lipid Peroxidation by Doxorubicin Analogues (1989) (5)
- The interaction of adriamycin and its beta anomer with DNA. (1977) (5)
- Influence of some antitumor antibiotics on viral neoplasia (1972) (5)
- Cellular sensitivity to beta-diketonato complexes of ruthenium(III), chromium(III) and rhodium(III). (2006) (5)
- Evaluation of a platinum-doxorubicin complex in experimental tumor systems (1990) (5)
- Defining targets of modulation of human tumor cell response to cisplatin. (2008) (5)
- Prevention of cyclophosphamide-induced urotoxicity by reduced glutathione and its effect on acute toxicity and antitumor activity of the alkylating agent (2004) (5)
- Sequence-Selective Groove Binders (1997) (5)
- Antitumor Inhibitors of DNA Topoisomerases (1995) (5)
- Gene expression profiles in the cellular response to a multinuclear platinum complex. (2004) (5)
- Reactivity and Performance of Limestone Calcined-Clay Cement (LC 3 ) Cured at Low Temperature (2018) (5)
- Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage (1994) (5)
- DNA Polymerases of Rat Liver (1975) (5)
- Topical Administration of Tetrasodium-Mesotetraphenyl-Porphinesulfonate (TPPS): Correlation between Drug Penetration and Depth of Necrosis in Skin of Nude Mice following Red Light Irradiation (1987) (5)
- Semisynthesis of new D-seco-C-nor-taxane derivatives containing a polyfunctionalized furanosyl or cyclopentenyl or cyclopentyl C-ring. (2008) (4)
- Antitumor Complexes of Platinum with Carrier Molecules. Part 3. Cytotoxicity of Some Platinum Amino Acid Complexes Against Cisplatin-sensitive and Resistant L1210 Leukemia Cells (1986) (4)
- Different interaction of cisplatin and etoposide on in vivo and in vitro tumor systems. (1990) (4)
- Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin (1997) (4)
- Biochemical and biological activity of the anthracycline analog, 4-demethyl-6-0-methyl-doxorubicin (2004) (4)
- 3‐Arylidene‐N‐hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity (2016) (4)
- DNA topoisomerase inhibitors. (1994) (4)
- A Preliminary Clinical Study of Cyclophosphamide with Reduced Glutathione Asc Uroprotector (1989) (4)
- A Perspective on Wilderness in Europe (2007) (4)
- The Effect of Calcite and Gibbsite Impurities in Calcined Clay on Its Reactivity (2020) (4)
- The influence of sulfate addition on hydration kinetics and C-S-H morphology of C3S and C3S/C3A systems (2022) (3)
- Influence of calcium and calcium-modulating agents on differentiation of murine erythroleukaemia cells. (1985) (3)
- The human homolog of fission yeast Rad17 is implicated in tumor growth. (2008) (3)
- Hematoporphyrin-Derivative and Phototherapy in Extensive Basal-Cell Carcinoma of the Dorsal Skin (1984) (3)
- Assessing the Effect of Calcite Impurities in Clay on Optimal Dehydroxylation Parameters for Enhanced Reactivity (2018) (3)
- Improved apoptotic cell death in drug-resistant non small cell lung cancer cells by TRAIL-based treatment (2013) (3)
- Camptothecin derivatives with antitumor activity. (1999) (3)
- More sustainable constructions using limestone calcined clay cement (LC³) (2019) (3)
- Oxidation of pyrite (FeS2) and troilite (FeS) impurities in kaolinitic clays after calcination (2021) (3)
- Structure analysis of beta dicalcium silicate via scanning transmission electron microscope (STEM) (2022) (3)
- Durability performance of binary and ternary blended cementitious systems with calcined clay: a RILEM TC 282 CCL review (2022) (3)
- Absence of anthracycline-induced degradation of nuclear DNA in Ehrlich ascites tumour cells. (1979) (3)
- Changes in the three-dimensional organization of LoVo cells associated with resistance to doxorubicin. (1989) (3)
- DNA polymerases of rat liver. Partial characterization and effect of various inhibitors. (1975) (2)
- RET/PTC-1-driven transformation and pro-invasive phenotype of human thyrocytes depend on MET induction and alpha-catenin nuclear translocation (2009) (2)
- Differential outcome of MEK 1 / 2 inhibitor-platinum combinations in platinum-sensitive and-resistant ovarian carcinoma cells (2014) (2)
- Small-Cell Lung Cancer Xenografts in Drug Resistance Studies (1992) (2)
- Biochemical and biological activity of the anthracycline analog, 4-demethyl-6-O-methyl-doxorubicin. (1986) (2)
- Effect of amrinone on anthracycline-induced lethal and cardiac toxicity in mice and rats (1990) (2)
- Processing of Calcined Clays for Applications in Cementitious Materials: The Use of Grinding Aids and Particle Classification After Grinding (2019) (2)
- High-Dose Cisplatin with Glutathione Protection in Gynecologic Malignancies (1991) (2)
- Chemical vs. Physical Acceleration of Cement Hydration: CaCl2 vs. Limestone Powder | NIST (2016) (2)
- ICION3 and chemotheraphy for avarian camcer (2002) (2)
- Cisplatin and fluorouracil concurrent to radiotherapy in nasopharyngeal cancer: is the schedule compatible? (2004) (2)
- γ‐GLUTAMYLTRANSFERASE OF CANCER CELLS AT THE CROSSROADS AMONG TUMOR PROGRESSION, DRUG RESISTANCE AND DRUG TARGETING. (2009) (2)
- Cancer Therapy : Preclinical SST 0001 , a Chemically Modified Heparin , Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase / Syndecan-1 Axis (2011) (2)
- MiR-146a up-Regulation Is Associated with Anti-Tumor Activity of Pan-Histone Deacetylase Inhibitor ITF2357 (Givinostat®) in Human Burkitt's Lymphoma (2011) (2)
- Current approaches to new drug development in cancer chemotherapy. (1992) (2)
- DNA Minor-Groove Binding Drugs (1995) (2)
- Modulation of epidermal growth factor receptor tyrosine phosphorylation by tumor necrosis factor. (1991) (2)
- Differences in activity of mitoxantrone (DHAD) plus ifosfamide (IFO) according to previous platinum-compound (PC) responsiveness in advanced ovarian cancer (AOC). An I.T.M.O. group study (1993) (2)
- Synthesis and Cytotoxic Activity of Substituted 7‐Aryliminomethyl Derivatives of Camptothecin. (2004) (2)
- Intralesional topotecan in advanced ovarian cancer: a clinical report, based on a preclinical study. (2002) (1)
- p 53 in drug resistance in ovarian cancer (2005) (1)
- Mitoxantrone and ifosfamide as second-line therapy of epithelial ovarian cancer. A pilot study by the I.T.M.O. Group. (1994) (1)
- Improving the Behaviour of Calcined Clay as Supplementary Cementitious Materials by a Combination of Controlled Grinding and Particle Selection (2020) (1)
- Platinum (II) complexes, methods for their preparation and use as antitumor agents. (1989) (1)
- Interaction of daunomycin with nucleic acids: Effect of photoirradiation of the complex (1972) (1)
- Hydration and mixture design of calcined clay blended cements: review by the RILEM TC 282-CCL (2022) (1)
- ICON3 and chemotherapy for ovarian cancer. (2002) (1)
- Reduction of Lethal Toxicity of Doxorubicin by Amrinone (1982) (1)
- Advances in Brief BBR 3464 : A Novel Triplatinum Complex , Exhibiting a Preclinical Profile of Antitumor Efficacy Different from Cisplatin 1 (2000) (1)
- Novel Cytotoxic 7‐Iminomethyl and 7‐Aminomethyl Derivatives of Camptothecin. (2001) (1)
- Cellular sensitivity to β-diketonato complexes of ruthenium(III) and chromium(III). (2006) (1)
- A comparison of efficacy of photoradiation therapy and other conventional treatment modalities on experimental MS-2 sarcoma. (1984) (1)
- The Origin of the Increased Sulfate Demand of Blended Cements Incorporating Aluminum-Rich Supplementary Cementitious Materials (2020) (1)
- ICON3 and chemotherapy for ovarian cancer. Authors' reply (2002) (1)
- Sequence-specific poisons of type II DNA topoisomerases (1998) (1)
- ANTITUMOR COMPLEXES OF PLATINUM WITH CARRIER MOLECULES. 2. MIXED COMPLEXES OF F AMINO ACIDS AND TERT-BUTYLAMINE (1985) (1)
- A novel inhibitor of vacuolar H+-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems. (2006) (1)
- [Pharmacologic basis of the effectiveness of topotecan in the treatment of ovarian carcinoma]. (1999) (1)
- Synergistic apoptosis and antitumor activity induced by ST1926, an atypical retinoic acid derivative (2007) (1)
- Chromatographic Purification of Plant Viruses on Magnesium Pyrophosphate Gel (1969) (1)
- 80 Membrane gamma-glutamyltransferase as a target for intervention on several redox-modulated functions of the cancer cell (2004) (1)
- Paper of RILEM TC 282-CCL: mineralogical characterization methods for clay resources intended for use as supplementary cementitious material (2022) (0)
- Low-temperature curing strength enhancement in cement-based materials containing limestone powder (2017) (0)
- Antitumor activity of a new synthetic camptothecin with the open lacton ring. (2006) (0)
- Cancer Therapy : Preclinical SynergisticAntitumorActivityofCetuximabandNamitecan in Human Squamous Cell Carcinoma Models Relies on Cooperative Inhibition of EGFR Expression and Depends on High EGFR Gene Copy Number (2014) (0)
- 511 Potentiation of cell sensitivity to the DNA topoisomerase I inhibitor gimatecan by TRAIL in prostate carcinoma cells (2004) (0)
- Erratum: The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates (Bioconjugate Chemistry (2009:20) (629) DOI:10.1021/bc800535j) (2009) (0)
- [Molecular basis of viral induced tumors (author's transl)]. (1973) (0)
- CellCycleCheckpointEff|ciencyandCellular ResponsetoPaclitaxelinProstateCancerCells (2001) (0)
- Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas (2016) (0)
- Secondary Mould Metabolites. Part 59. Sesquiterpene Illudanes: Semi‐Synthesis of New Illudins, Structures and Biological Activity. (2001) (0)
- Membrane gamma-glutamyltransferase activity: a possible target for intervention on several redox-modulated functions in the cancer cell (2005) (0)
- 323 Targeting the MAPK pathway to increase sensitivity of ovarian carcinoma cells to platinum compounds (2010) (0)
- Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043] (2010) (0)
- Influence of fluorodesoxyuridine (FdUrd) on linear growth and DNA synthesis in Sinapis alba L (1972) (0)
- 3-Arylideneindolin-2-ones as inhibitors of MDM2-p53 interaction (2015) (0)
- Synthesis, modeling and RET protein kinase inhibitory activity of substituted β-carbolin-2-ones and dihydro-2H-azepino3,4-bindol-1-ones (2008) (0)
- Abstract B224: Multi‐tyrosine kinase targeting resulting in concomitant downregulation of proliferation/survival pathways dependent on FGF‐R3, Jak2 and BCMA in human multiple myeloma cells (2009) (0)
- Sensitivity to anthracyclines in P388/dx leukaemia cells. (1986) (0)
- Eradication of OvarianTumor Xenografts by Locoregional Administration ofTargeted Immunotherapy (2008) (0)
- 56 A novel interplay between Ret oncoprotein and Fap-1 controls CD95-mediated apoptosis in medullary thyroid cancer (2010) (0)
- O . Group Study on Second-line Treatment in Advanced Epithelial Ovarian Cancer : an Attempt to Identify Clinical and Biological F actors Determining Prognosis (2015) (0)
- Cytotoxicity cellular pharmacokinetics and dna strand breaks produced by doxorubicin dx 4 demethyl 6 deoxy dx dddx and 9 deoxy dx 9ddx in p388 cells (1988) (0)
- Cooperative antitumor and antiangiogenic activity after oral administration of a novel taxane, an antisense targeting protein kinase A and the EGF receptor inhibitor Iressa (2001) (0)
- Gamma-glutamyltransferase activity of melanoma cells: tumor progression and cancer drug resistance (2009) (0)
- Biphenyl and naphthylphenyl hydroxamic acid derivatives (2006) (0)
- In Vitro and in Vivo Studies of Poly-L-Lysine as Inducer of Friend Leukemic Cells Differentiation (1987) (0)
- Meeting abstractPoly-L-lysine as differentiation inducer in friend erythroleukaemia: Studies in vitro and in vivo (1987) (0)
- Abstract C206: High antitumor complete response rate to Namitecan (ST1968) in preclinical model of pediatric sarcomas. (2011) (0)
- Abstract 2623: ST3595, a new histone deacetylase (HDAC) inhibitor endowed with a peculiar mechanism of action (2011) (0)
- 156 DNA damage induced by camptothecins is stabilized by G-quadruplex ligands (2010) (0)
- Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 72: Absract (2003) (0)
- Abstract 566: Interaction of acetyl-L-carnitine with platinum compounds: A possible role of protein acetylation in modulation of antitumor activity (2010) (0)
- Synthesis and Evaluation of Biological Activity of Binuclear Cisplatin Analogues with Polyoxypropylene‐α,ω‐diamines as the Bridging Groups. (1989) (0)
- Enhancement of mitogenic stimuli by phosphatidylinositol. (1983) (0)
- Abstract C34: Synergistic interaction between a novel histone deacetylase inhibitor and the proteasome inhibitor bortezomib in platinum-resistant ovarian carcinoma cells. (2011) (0)
- In vitro modulation of CD95 expression on a human glioblastoma cell line by various chemotherapeutic drugs (2000) (0)
- LC 3 : a promising alternative (2019) (0)
- RILEM TC 282-CCL, CALCINED CLAYS AS SUPPLEMENTARY CEMENTITIOUS MATERIALS Hydration and mixture design of calcined clay blended cements: review by the RILEM (2023) (0)
- Atomic Structure Analysis of Beta Dicalcium Silicate and its Active Oxygen Atoms Via Scanning Transmission Electron Microscope (Stem) (2022) (0)
- Novel HDAC inhibitors with a phenylcinnamic scaffold: synthesis and evaluation of antitumor activity (2015) (0)
- Short Synthesis of Cytotoxic 4‐Arylcoumarins. (2006) (0)
- Camptothecins, which is conjugated at the 7-position to the cyclic peptides as cytostatic agents (2005) (0)
- The Challenge of Grinding Ternary Blends Containing Calcined Clays and Limestone (2022) (0)
- The impact of calcite impurities in clays containing kaolinite on their reactivity in cement after calcination (2020) (0)
- TOPOISOMERASE II AND DRUG SENSITIVITY IN HUMAN LUNG CANCER CELLS MATERIALS AND METHODS Cell Lines and Cytotoxicity Assay (2006) (0)
- Characterisation and hydration kinetics of β-C2S synthesised with K2SO4 as dopant (2023) (0)
- The potential role of gamma-glutamyltransferase (GGT) as a factor of genomic instability and tumor progression (2006) (0)
- Campotecinderivate and their use as antitumor agents (1997) (0)
- Abstract A93: Targeting the increased invasive capability of non-small cell lung cancer platinum-resistant cells by histone deacetylase inhibitors. (2013) (0)
- Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma (2012) (0)
- Structural studies on ST1481, gimatecan, a 7-substituted camptothecin with anti-tumor activity (2005) (0)
- Influence of Kaolinite Content, Limestone Particle Size and Mixture Design on Early-Age Properties of Limestone Calcined Clay Cements (LC3) (2020) (0)
- Inhibition of DNA synthesis in RNA tumor viruses by antitumor antibiotics. (1972) (0)
- Camptothecin derivatives and their use as antitumor agents. (1997) (0)
- Gamma-Glutamyltransferase-Dependent Resistance of Melanoma Cells to Arsenic Trioxide – The Role of Catalase induction (2008) (0)
- Correction to: The impact of calcite impurities in clays containing kaolinite on their reactivity in cement after calcination (2021) (0)
- LE CAMPTOTECINE : MECCANISMO DI AZIONE E STUDI PRECLINICI CAMPTOTHECINS : MECHANISM OF ACTION AND PRECLINICAL STUDIES (1997) (0)
- Inhibitors of mammalian DNA topoisomerases (1995) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Franco Zunino?
Franco Zunino is affiliated with the following schools:
