Frank Bradke
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German neurobiologist
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Frank Bradkebiology Degrees
Biology
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Neuroscience
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#2574
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Biology
Why Is Frank Bradke Influential?
(Suggest an Edit or Addition)According to Wikipedia, Frank Bradke is a German neurobiologist who works on the physiological regeneration of nerve cells in the central nervous system. In 2016, he was awarded the Gottfried Wilhelm Leibniz Prize for his "pioneering research in the field of regenerative neurobiology." He is currently a Group Leader at the German Center for Neurodegenerative Diseases. He is a member of the Editorial Board for Current Biology.
Frank Bradke's Published Works
Published Works
- Lifeact: a versatile marker to visualize F-actin (2008) (1985)
- Three-dimensional imaging of solvent-cleared organs using 3DISCO (2012) (769)
- Regeneration of Sensory Axons within the Injured Spinal Cord Induced by Intraganglionic cAMP Elevation (2002) (546)
- The role of local actin instability in axon formation. (1999) (534)
- Microtubule stabilization specifies initial neuronal polarization (2008) (502)
- Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury (2011) (489)
- Assembly of a new growth cone after axotomy: the precursor to axon regeneration (2012) (370)
- Disorganized Microtubules Underlie the Formation of Retraction Bulbs and the Failure of Axonal Regeneration (2007) (350)
- Systemic administration of epothilone B promotes axon regeneration after spinal cord injury (2015) (302)
- Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury (2011) (301)
- Lifeact mice for studying F-actin dynamics (2010) (295)
- Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation (2010) (261)
- Cdc42 Regulates Cofilin during the Establishment of Neuronal Polarity (2007) (259)
- Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease (2012) (244)
- Neuronal Polarity: Vectorial Cytoplasmic Flow Precedes Axon Formation (1997) (230)
- The role of the cytoskeleton during neuronal polarization (2008) (223)
- Establishment of neuronal polarity: lessons from cultured hippocampal neurons (2000) (214)
- Coordinating Neuronal Actin–Microtubule Dynamics (2015) (213)
- ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain (2012) (180)
- Neuronal polarization: The cytoskeleton leads the way (2011) (172)
- Control of neuronal polarity and plasticity--a renaissance for microtubules? (2009) (164)
- Rac1 Regulates Neuronal Polarization through the WAVE Complex (2010) (159)
- The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS (2016) (158)
- A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system. (2014) (143)
- PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system (2014) (141)
- Chronically CNS-Injured Adult Sensory Neurons Gain Regenerative Competence upon a Lesion of Their Peripheral Axon (2009) (129)
- Growth cone‐like waves transport actin and promote axonogenesis and neurite branching (2009) (127)
- Netrin-1 Is a Novel Myelin-Associated Inhibitor to Axon Growth (2008) (124)
- Plasticity of Polarization: Changing Dendrites into Axons in Neurons Integrated in Neuronal Circuits (2008) (115)
- Luminal particles within cellular microtubules (2006) (112)
- An assay to image neuronal microtubule dynamics in mice (2014) (111)
- The DLK signalling pathway—a double‐edged sword in neural development and regeneration (2013) (108)
- Axon Regeneration in the Central Nervous System: Facing the Challenges from the Inside. (2018) (105)
- Cytoskeleton dynamics in axon regeneration (2018) (104)
- Regulation of Rat Schwann Cell Po Expression and DNA Synthesis by Insulin‐like Growth Factors In Vitro (1996) (104)
- Three-dimensional imaging of solvent-cleared organs using 3 DISCO (2012) (103)
- Can injured adult CNS axons regenerate by recapitulating development? (2017) (97)
- Differentiated neurons retain the capacity to generate axons from dendrites (2000) (97)
- Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex (2017) (96)
- Spatial and temporal arrangement of neuronal intrinsic and extrinsic mechanisms controlling axon regeneration (2017) (94)
- Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem (2020) (92)
- Neuronal polarization: From spatiotemporal signaling to cytoskeletal dynamics (2017) (87)
- Neuronal polarity. (2009) (82)
- High-resolution imaging of entire organs by 3-dimensional imaging of solvent cleared organs (3DISCO) (2013) (81)
- Neuronal polarization and the cytoskeleton. (2011) (80)
- Electrical Activity Suppresses Axon Growth through Cav1.2 Channels in Adult Primary Sensory Neurons (2010) (78)
- Cytoplasmic Linker Proteins Regulate Neuronal Polarization through Microtubule and Growth Cone Dynamics (2011) (75)
- Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis (2018) (71)
- Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections (2016) (69)
- In vivo imaging A dynamic imaging approach to study spinal cord regeneration (2013) (66)
- A Chemical Screen Identifies Novel Compounds That Overcome Glial-Mediated Inhibition of Neuronal Regeneration (2010) (62)
- Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition (2011) (59)
- RhoA Controls Axon Extension Independent of Specification in the Developing Brain (2019) (59)
- Cryo Electron Tomography of Herpes Simplex Virus during Axonal Transport and Secondary Envelopment in Primary Neurons (2011) (56)
- Membrane traffic in polarized neurons. (1998) (55)
- ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS (2019) (51)
- The centrosome protein AKNA regulates neurogenesis via microtubule organization (2019) (51)
- Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics (2012) (49)
- Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction[S] (2016) (46)
- Axon Growth of CNS Neurons in Three Dimensions Is Amoeboid and Independent of Adhesions. (2020) (42)
- Systemic administration of epothilone D improves functional recovery of walking after rat spinal cord contusion injury (2017) (42)
- Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats (2018) (35)
- Changes in membrane trafficking and actin dynamics during axon formation in cultured hippocampal neurons (2000) (32)
- Macroporous hydrogels derived from aqueous dynamic phase separation. (2019) (32)
- RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury (2021) (31)
- Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics (2015) (31)
- Development and differentiation of Schwann cells. (1996) (24)
- Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis (2015) (23)
- An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury (2021) (19)
- High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing (2019) (18)
- Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations (2019) (17)
- A Dual SILAC Proteomic Labeling Strategy for Quantifying Constitutive and Cell-Cell Induced Protein Secretion. (2015) (13)
- The Effect of Non-Gabapentinoid Anticonvulsants on Sensorimotor Recovery After Human Spinal Cord Injury (2019) (12)
- New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules (2019) (11)
- Neuronal Maturation: Challenges and Opportunities in a Nascent Field (2020) (10)
- Single-cell axotomy of cultured hippocampal neurons integrated in neuronal circuits (2014) (9)
- Editorial overview: Development and regeneration: Nervous system development and regeneration (2014) (8)
- AAV‐mediated expression of BAG1 and ROCK2‐shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury (2015) (8)
- Controlled Demolition: Smurf1 Regulates Neuronal Polarity by Substrate Switching (2011) (7)
- Imaging in vivo dynamics of sensory axon responses to CNS injury (2019) (7)
- Neuronal transport: myosins pull the ER (2011) (6)
- Cytoskeleton in Axon Growth (2009) (6)
- Epothilones Improve Axonal Growth and Motor Outcomes after Stroke in the Adult Mammalian CNS (2020) (6)
- Role of the cytoskeleton and membrane trafficking in axon–dendrite morphogenesis (2020) (5)
- In Situ Visualization of Axon Growth and Growth Cone Dynamics in Acute Ex Vivo Embryonic Brain Slice Cultures. (2021) (4)
- Microtubule Organization in the Axon: TRIM46 Determines the Orientation (2015) (4)
- Microtubule retrograde flow retains neuronal polarization in a fluctuating state (2021) (4)
- A New “Spin” on Recovery after Spinal Cord Injury (2014) (3)
- Videomicroscopy of Living Microinjected Hippocampal Neurons in Culture (1998) (3)
- Microtubule Self-Organization via Protein-RNA Network Crosstalk (2014) (3)
- Cryo-electron Tomography Workflows for Quantitative Analysis of Actin Networks Involved in Cell Migration (2020) (3)
- Stimulating Intrinsic Growth Potential in Mammalian Neurons (2007) (3)
- Reproducibility – The key towards clinical implementation of spinal cord injury treatments? (2019) (3)
- Beneficial “Pharmaceutical Pleiotropy” of Gabapentinoids in Spinal Cord Injury: A Case for Refining Standard-of-Care (2020) (2)
- Guidance of Axons to Targets in Development and in Disease (2005) (2)
- Cryo-Electron Tomography of Intact Cells (2007) (2)
- Enhancing the Regeneration of Neurons in the Central Nervous System (2019) (2)
- Moving through the crowd. Where are we at understanding physiological axon growth? (2022) (1)
- Faculty Opinions recommendation of Reactivation of dormant relay pathways in injured spinal cord by KCC2 manipulations. (2018) (1)
- Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury (2023) (1)
- Pharmacological Management of Acute Spinal Cord Injury: Overlooked Opportunities to Enhance Long-Term Neurological Function (2019) (1)
- Methods for culturing adult CNS neurons reveal a CNS conditioning effect (2022) (1)
- Acknowledgment of Guest Editors, 2019 (2019) (1)
- Pregabalin improves axon regeneration and motor outcome in a rodent stroke model (2022) (1)
- Editorial overview: Microtubules in nervous system development (2021) (1)
- Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain (2023) (1)
- Extracellular matrix and oligodendrocyte regulators in different types of multiple sclerosis lesions : Implications for lesion development and regulation of remyelination (2010) (0)
- Faculty Opinions recommendation of Profilin1 delivery tunes cytoskeleton dynamics towards CNS axon regeneration. (2020) (0)
- Editorial overview: Molecular neuroscience (2021) (0)
- Mechanisms of Axon Growth and Regeneration: Moving between Development and Disease (2022) (0)
- Supporting Online Material for Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury (2010) (0)
- Rac1 regulates neuronal migration and axon growth in the cerebellum (2009) (0)
- Faculty Opinions recommendation of Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury. (2021) (0)
- Intracellular mechanisms of initial neuronal polarization (1998) (0)
- Faculty Opinions recommendation of Cell membranes resist flow. (2019) (0)
- overview : Development and regeneration : Nervous system development and regeneration (2014) (0)
- Faculty Opinions recommendation of Stereotyped transcriptomic transformation of somatosensory neurons in response to injury. (2020) (0)
- Faculty Opinions recommendation of Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury (2020) (0)
- Novel compounds that overcome inhibition of CNS regeneration (2009) (0)
- Mesencephalic locomotor region stimulation—cuneiform or pedunculopontine? (2023) (0)
- Faculty Opinions recommendation of Vasohibins encode tubulin detyrosinating activity. (2019) (0)
- Abbreviations: alkyne-doxSA: (2S,3R)-2-aminooctadec-17-yn-3-ol; alkyne-SA: (2S,3R)-2- aminooctadec-17-yn-1,3-diol; ASTM-BODIPY: azido-sulfo-tetramethyl-BODIPY; CE: cholesterolester; Cer: ceramide; CerS: ceramide synthase; DHCer; dihydroceramide; deoxySLs: 1-deoxysphingolipids; doxCer: 1-deoxyceramid (2016) (0)
- The novel stress inducible gene MPIP101 modulates neurite formation via changes in Actin dynamics (2009) (0)
- Advisory Board and Contents (2020) (0)
- Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development (2022) (0)
- Generation of microRNA-Sensitive VSV Vectors for Safer Treatment of Hepatocellular Carcinoma and Hepatic Metastasis of Colorectal Cancer (2010) (0)
- Faculty Opinions recommendation of Microglia-organized scar-free spinal cord repair in neonatal mice. (2020) (0)
- High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing (2019) (0)
- The centrosome protein AKNA regulates neurogenesis via microtubule organization (2019) (0)
- Growing Myelin around Regenerated Axons after CNS Injury (2020) (0)
- Faculty Opinions recommendation of Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. (2019) (0)
- Thanks to everyone for making this meeting happen ! (2017) (0)
- ADF/Cofilin is necessary for neuritogenesis in the developing mammalian brain (2010) (0)
- Salamanca, Spain Communications (2005) (0)
- Faculty Opinions recommendation of Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. (2019) (0)
- Faculty Opinions recommendation of Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. (2019) (0)
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What Schools Are Affiliated With Frank Bradke?
Frank Bradke is affiliated with the following schools: