Frank Dudbridge
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Statistical geneticist and genetic epidemiologist
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Frank Dudbridgemedical Degrees
Medical
#1995
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#2384
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Epidemiology
#340
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#358
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Frank Dudbridgebiology Degrees
Biology
#8018
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#11027
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Genetics
#785
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#877
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Medical Biology
Frank Dudbridge's Degrees
- Masters Statistics University of Oxford
Why Is Frank Dudbridge Influential?
(Suggest an Edit or Addition)According to Wikipedia, Frank Dudbridge is Professor of Statistical Genetics in the Department of Health Sciences at the University of Leicester, where he has worked since 2016. His research focuses on the fields of statistical genetics and genetic epidemiology as they relate to common human diseases. Before joining the University of Leicester, he served first as a senior statistician at the MRC Biostatistics Unit at the University of Cambridge, then as Reader and Professor of Statistical Genetics at the London School of Hygiene and Tropical Medicine.
Frank Dudbridge's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Genome-wide association study identifies five new schizophrenia loci (2011) (1680)
- Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia (2013) (1455)
- Power and Predictive Accuracy of Polygenic Risk Scores (2013) (1259)
- Haplotype tagging for the identification of common disease genes (2001) (1248)
- Pedigree disequilibrium tests for multilocus haplotypes (2003) (1180)
- Common variants on chromosome 6p22.1 are associated with schizophrenia (2009) (1146)
- A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) (1125)
- Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 (2011) (929)
- The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis (2012) (864)
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2016) (736)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- Estimation of significance thresholds for genomewide association scans (2008) (656)
- Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data (2008) (652)
- Research review: Polygenic methods and their application to psychiatric traits. (2014) (580)
- Mendelian randomization of blood lipids for coronary heart disease (2014) (580)
- Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress (2004) (579)
- HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials (2015) (559)
- Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data (2014) (547)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants (2015) (471)
- Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. (2011) (401)
- Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods (2015) (380)
- Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress (2004) (374)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults (2018) (359)
- Genes related to sex steroids, neural growth, and social–emotional behavior are associated with autistic traits, empathy, and Asperger syndrome (2009) (289)
- Guidelines for performing Mendelian randomization investigations (2019) (268)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. (2018) (257)
- A HaemAtlas: characterizing gene expression in differentiated human blood cells (2008) (255)
- Using genetic data to strengthen causal inference in observational research (2018) (254)
- Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis (2017) (239)
- Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C (2014) (213)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- Guidelines for performing Mendelian randomization investigations. (2019) (199)
- A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait. (2015) (197)
- The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks (2005) (196)
- Re: "Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects". (2015) (172)
- Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. (2004) (167)
- Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. (2007) (163)
- Variants in the fetal genome near FLT1 are associated with risk of preeclampsia (2017) (159)
- Correction: Power and Predictive Accuracy of Polygenic Risk Scores (2013) (147)
- A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. (2009) (143)
- Polygenic Epidemiology (2016) (134)
- Rank truncated product of P‐values, with application to genomewide association scans (2003) (129)
- Fractal approximation of image blocks (1992) (126)
- Unbiased application of the transmission/disequilibrium test to multilocus haplotypes. (2000) (126)
- Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD (2005) (123)
- Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor (2009) (123)
- Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease (2004) (115)
- Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. (2012) (115)
- Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis (2016) (110)
- Maximizing association statistics over genetic models (2008) (110)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Estimation of a significance threshold for epigenome‐wide association studies (2017) (106)
- Epigenome-based cancer risk prediction: rationale, opportunities and challenges (2018) (104)
- Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis (2015) (100)
- Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. (2010) (98)
- Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21. (2000) (97)
- Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. (2001) (97)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- Fractal block coding of images (1992) (92)
- Whole-genome sequence-based analysis of thyroid function (2015) (89)
- Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes (2014) (84)
- Capture Hi-C identifies putative target genes at 33 breast cancer risk loci (2018) (83)
- Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins (2008) (83)
- Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus (2007) (77)
- Fibrinogen Aα Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension (2008) (77)
- Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents† (2010) (75)
- Gene-Environment Dependence Creates Spurious Gene-Environment Interaction (2014) (75)
- A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis (2010) (72)
- Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits (2014) (69)
- The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1. (2001) (69)
- Genome‐wide analysis of adolescent psychotic‐like experiences shows genetic overlap with psychiatric disorders (2018) (68)
- Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women (2020) (67)
- Robust instrumental variable methods using multiple candidate instruments with application to Mendelian randomization (2016) (67)
- Genome-wide association study of multiplex schizophrenia pedigrees. (2012) (66)
- Evaluation of Nyholt’s Procedure for Multiple Testing Correction (2005) (65)
- Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis. (2012) (64)
- Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort (2006) (62)
- Are Genetic Risk Factors for Psychosis Also Associated with Dimension-Specific Psychotic Experiences in Adolescence? (2014) (62)
- Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density (2016) (61)
- A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2020) (60)
- Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses (2021) (60)
- Adjustment for index event bias in genome-wide association studies of subsequent events (2018) (60)
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. (2015) (58)
- Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test (2000) (58)
- An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD (2007) (56)
- Unbiased estimation of odds ratios: combining genomewide association scans with replication studies (2009) (55)
- Robust methods in Mendelian randomization via penalization of heterogeneous causal estimates (2019) (55)
- Multi-Polygenic Score Approach to Identifying Individual Vulnerabilities Associated With the Risk of Exposure to Bullying. (2019) (54)
- What role for genetics in the prediction of multiple sclerosis? (2010) (54)
- Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment (2021) (53)
- Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier (2011) (52)
- Comparison of Methods for Competitive Tests of Pathway Analysis (2012) (52)
- Functional genetic polymorphisms in cytokines and metabolic genes as additional genetic markers for susceptibility to develop type 1 diabetes (2004) (51)
- Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2 (2015) (50)
- Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium (2013) (50)
- Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference (2018) (49)
- Rendering algorithms for deterministic fractals (1995) (47)
- Detecting multiple associations in genome-wide studies (2006) (47)
- Family-based association studies. (2011) (46)
- Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs (2011) (46)
- Retrospective analysis of the quality of reports by author-suggested and non-author-suggested reviewers in journals operating on open or single-blind peer review models (2015) (46)
- Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men (2011) (45)
- Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1. (2001) (44)
- Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes (2003) (44)
- Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI. (2012) (43)
- Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in‐depth exon resequencing and genotyping with tag single nucleotide polymorphisms (2006) (40)
- Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. (2008) (38)
- Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts (2020) (35)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (31)
- Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation (2012) (30)
- Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents (2015) (29)
- A note on permutation tests in multistage association scans. (2006) (29)
- Predictive accuracy of combined genetic and environmental risk scores (2017) (29)
- Deterministic rendering of self-affine fractals (1990) (29)
- Genetic Determinants of Major Blood Lipids in Pakistanis Compared With Europeans (2010) (29)
- Association of Common Genetic Variants with Lipid Traits in the Indian Population (2014) (29)
- Fibrinogen Aalpha Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension. (2008) (28)
- A genome-wide association study of asthma symptoms in Latin American children (2015) (28)
- A survey of current software for linkage analysis (2003) (28)
- A general framework for two-stage analysis of genome-wide association studies and its application to case-control studies. (2012) (27)
- Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer. (2016) (27)
- Marginal role for 53 common genetic variants in cardiovascular disease prediction (2016) (26)
- Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention (2018) (26)
- Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon. (2012) (26)
- Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts (2018) (25)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- A flexible and parallelizable approach to genome‐wide polygenic risk scores (2019) (25)
- Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation (2017) (25)
- A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis (2010) (24)
- 9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium (2012) (24)
- Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis. (2009) (23)
- Are your covariates under control? How normalization can re-introduce covariate effects (2017) (23)
- Impact of Selection Bias on Estimation of Subsequent Event Risk (2017) (23)
- Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts (2020) (23)
- Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome. (2006) (23)
- Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test. (2000) (22)
- Conditional ETDT analysis of the Human Leukocyte Antigen region in type 1 diabetes (2000) (22)
- Least-squares block coding by fractal functions (1995) (22)
- Genetic Prediction of Quantitative Lipid Traits: Comparing Shrinkage Models to Gene Scores (2014) (21)
- Family‐Based Association (2008) (21)
- Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors (2017) (21)
- Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort (2016) (21)
- Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events (2019) (21)
- Pelican: pedigree editor for linkage computer analysis (2004) (20)
- Common Sequence Variation in FLNB Regulates Bone Structure in Women in the General Population and FLNB mRNA Expression in Osteoblasts In Vitro (2009) (20)
- Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations (2019) (20)
- Association Study of 25 Type 2 Diabetes Related Loci with Measures of Obesity in Indian Sib Pairs (2013) (20)
- Genetic overlap between psychotic experiences in the community across age and with psychiatric disorders (2019) (19)
- Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study (2018) (18)
- Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study. (2019) (18)
- Candidate gene-environment interactions in breast cancer (2014) (17)
- Robust genetic nurture effects on education: A systematic review and meta-analysis based on 38,654 families across 8 cohorts. (2021) (16)
- Accuracy of Gene Scores when Pruning Markers by Linkage Disequilibrium (2016) (16)
- Copy number variation of the APC gene is associated with regulation of bone mineral density☆ (2012) (15)
- RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation (2019) (15)
- Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits (2020) (15)
- Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget’s disease of bone (2019) (15)
- The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples (2022) (14)
- Subsequent Event Risk in Individuals With Established Coronary Heart Disease (2019) (14)
- Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases (2020) (14)
- Mendelian Randomisation study of the influence of eGFR on coronary heart disease (2016) (14)
- Association between Protective and Deleterious HLA Alleles with Multiple Sclerosis in Central East Sardinia (2009) (13)
- A comparison of the quality of reviewer reports from author-suggested reviewers and editor-suggested reviewers in journals operating on open or closed peer review models (2013) (13)
- A Flexible Model for Association Analysis in Sibships with Missing Genotype Data (2011) (13)
- Polygenic Mendelian Randomization. (2020) (13)
- Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study (2013) (13)
- Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data (2020) (13)
- New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries (2018) (12)
- Are there causal relationships between attention-deficit/hyperactivity disorder and body mass index? Evidence from multiple genetically informed designs. (2020) (12)
- Utilising Family-Based Designs for Detecting Rare Variant Disease Associations (2014) (12)
- Two novel pathway analysis methods based on a hierarchical model (2013) (12)
- Family history of pre-eclampsia and cardiovascular disease as risk factors for pre-eclampsia: the GenPE case-control study (2020) (12)
- Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia (2010) (11)
- Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival (2020) (11)
- Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes (2022) (10)
- Identification of variation in the platelet transcriptome associated with Glycoprotein 6 haplotype (2008) (10)
- Relative contributions of family history and a polygenic risk score on COPD and related outcomes: COPDGene and ECLIPSE studies (2020) (9)
- Guidelines for performing Mendelian randomization investigations [version 1; peer review: 1 approved, 1 approved with reservations] (2021) (9)
- Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal (2013) (9)
- Identifying high-confidence capture Hi-C interactions using CHiCANE (2020) (9)
- Interaction of Cigarette Smoking and Polygenic Risk Score on Reduced Lung Function (2021) (9)
- Association of Factor V Leiden With Subsequent Atherothrombotic Events (2020) (8)
- Evaluation of seven common lipid associated loci in a large Indian sib pair study (2012) (8)
- A robust method for collider bias correction in conditional genome-wide association studies (2022) (8)
- Criteria for evaluating risk prediction of multiple outcomes (2020) (8)
- Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG. (2019) (7)
- Estimating Causal Effects of Genetic Risk Variants for Breast Cancer Using Marker Data from Bilateral and Familial Cases (2011) (7)
- Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations (2020) (7)
- Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach (2020) (6)
- Genetic overlap and causal associations between smoking behaviours and mental health (2021) (6)
- Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study. (2021) (6)
- Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1L. (2021) (6)
- Guidelines for performing Mendelian randomization investigations [version 2; peer review: 2 approved] (2020) (6)
- Image Approximation by Self Aane Fractals (1992) (6)
- Commentary: Tobacco consumption and body weight: Mendelian randomization across a range of exposure (2015) (5)
- Genetic nurture effects on education: a systematic review and meta-analysis (2021) (5)
- Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome. (2008) (5)
- How many cases of disease in a pedigree imply familial disease? (2017) (4)
- Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2 (2008) (4)
- Genetic variation at CYP 3 A is associated with age at menarche and breast cancer risk : a case-control study (2014) (4)
- Smoking Interaction with a Polygenic Risk Score for Reduced Lung Function (2021) (4)
- Genome-wide association study using family-based cohorts identifies the WLS and CCDC 170 / ESR 1 loci as associated with bone mineral density (2016) (3)
- Re: Is the Risk Difference Really a More Heterogeneous Measure? (2016) (3)
- Fast and Robust Association Tests for Untyped SNPs in Case-Control Studies (2010) (3)
- Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes MellitusClinical Perspective (2017) (3)
- Causal analyses, statistical efficiency and phenotypic precision through Recall-by-Genotype study design (2017) (3)
- Variation in the FLNB gene regulates bone density in two populations of Caucasian women (2007) (3)
- Replication and Meta‐analysis of Genome‐Wide Association Studies (2019) (3)
- Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: prospective cohort study and modelling analysis (2019) (3)
- Deep-PheWAS: a pipeline for phenotype generation and association analysis for phenome-wide association studies. (2022) (3)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (3)
- On the dimension of fractally encoded images (1998) (2)
- Estimating the sensitivity of associations between risk factors and outcomes to shared genetic effects (2019) (2)
- Author Correction: Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment (2021) (2)
- Comparison of variance estimators for meta-analysis of instrumental variable estimates (2016) (2)
- Capture Hi-C identifies putative target genes at 33 breast cancer risk loci (2018) (2)
- Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk (2023) (2)
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (2)
- Are there causal relationships between ADHD and BMI? Evidence from multiple genetically informed designs (2020) (2)
- Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations (2007) (2)
- Association of polygenic risk scores for coronary artery disease with subsequent events amongst established cases (2019) (2)
- Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3. (2021) (2)
- Fine-mapping identi fi es two additional breast cancer susceptibility loci at 9 q 31 . 2 (2015) (2)
- Adjusting for collider bias in genetic association studies using instrumental variable methods (2022) (2)
- Evaluation of seven common lipid associated loci in a large Indian sib pair study (2012) (1)
- Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium (2013) (1)
- Erratum: Whole-genome sequence-based analysis of thyroid function (2015) (1)
- DeepPheWAS: an R package for phenotype generation and association analysis for phenome-wide association studies (2023) (1)
- Genetic overlap and causal associations between smoking behaviours and psychiatric traits and disorders in adolescents and adults (2020) (1)
- Mendelian randomisation analyses of eosinophils and other blood cell types in relation to lung function and disease. (2020) (1)
- Test to Identify Co-Localization of Genetic Association Signals Across Multiple Traits Using Summary Statistics (2016) (1)
- Rendering Algorithms for (1995) (1)
- RE: “INCIDENCE OF DEMENTIA AMONG PARTICIPANTS AND NONPARTICIPANTS IN A LONGITUDINAL STUDY OF COGNITIVE AGING” (2015) (1)
- Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer (2021) (1)
- Interpreting Association Signals (2011) (1)
- Self-reported walking pace, polygenic risk scores and risk of coronary artery disease in UK biobank. (2022) (1)
- The Genetic Sphygmomanometer: an argument for routine genome-wide genotyping in the population and a new view on its use to inform clinical practice (2018) (1)
- Are your covariates under control? How normalization can re-introduce covariate effects (2018) (1)
- Genome-wide analysis of adolescent psychotic experiences shows genetic overlap with psychiatric disorders (2018) (1)
- Linear time fractal quadtree coder (1998) (1)
- Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (1)
- Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease (2022) (1)
- A Fast Method Using Polygenic Scores to Estimate the Number of SNPs Contributing to a Trait and the Variance Explained by Genomewide SNP Panels (2013) (0)
- The impact of selection bias on estimation of subsequent event risk Running title: Selection bias in studies of subsequent CHD events (2017) (0)
- Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference (2018) (0)
- What is Mendelian Randomisation (2012) (0)
- cortisol and subsequent depression in at-risk adolescents Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning (2011) (0)
- Editorial: Fractal Image Encoding and Analysis (1997) (0)
- Linkage Analysis of Genetic Analysis Workshop 12 Simulated Data Based on Affected Individuals Only (2001) (0)
- Typhoid Fever and Genetic Polymorphisms at the Natural Resistance-Associated Macrophage Protein 1 (NRAMP1) (2012) (0)
- Application of the Optimal Discovery Procedure to Genetic Case-Control Studies: Comparison with p Values and Asymptotic Bayes Factors (2011) (0)
- Abstract 2908: Mesothelioma phylogeny reveal MTAP as a solitary clonal deletion, exposing vulnerability to the PRMT5 perturbagen, quinacrine (2019) (0)
- ISMB/ECCB 2013 Proceedings Papers Committee (2013) (0)
- Genome Mining for Actinomycete Biosynthetic Gene Clusters (2018) (0)
- Acknowledgement to the Reviewers (2006) (0)
- Poster #M139 INVESTIGATION INTO AN ASSOCIATION BETWEEN GENETIC RISK FACTORS FOR SCHIZOPHRENIA AND BIPOLAR DISORDER AND DIMENSION-SPECIFIC PSYCHOTIC EXPERIENCES IN ADOLESCENCE (2014) (0)
- Causal inference methods for intergenerational research using observational data. (2023) (0)
- Incorporating discovery and replication GWAS into summary data Mendelian randomization studies: A review of current methods and a simple, general and powerful alternative (2023) (0)
- PRELIMINARY RESULTS FROM THE FIRST GWAS ON INFANT FINE MOTOR SKILLS: CROSS AGE STABILITY AND RELEVANCE TO INTELLECTUAL DISABILITY (2022) (0)
- 188-LB: Type 2 Diabetes Is Genetically Correlated with Multiple Long-Term Conditions but These Correlations Are Only Partly Explained by BMI (2021) (0)
- Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (0)
- inhibitory platelet membrane proteins megakaryocytes and erythroblasts identifies novel activatory and Comparative gene expression profiling of in vitro differentiated (2013) (0)
- P50 Novel Activatory and Inhibitory Platelet Receptors Identified Through Comparative Gene Expression Profiling of Megakaryocytes and Erythroblasts (2006) (0)
- Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts (2020) (0)
- protein regulating platelet function Transcription profiling in human platelets reveals LRRFIP1 as a novel (2010) (0)
- SI09 Analysing Platelet Function in Blood Donors: Selection of Subjects for Functional Genetic Studies (2006) (0)
- Polygenic Risk Scores in Chronic Obstructive Pulmonary Disease and Related Phenotypes (2020) (0)
- Impact of past obstetric history and cervical excision on preterm birth rate (2021) (0)
- Assessment of causal relationships between eosinophils and respiratory disease using Mendelian randomization (2022) (0)
- YS03 Gene Expression Profiling of Platelet RNA Identifies Differentially Expressed Genes Associated with Collagen Signalling Responses (2006) (0)
- Edinburgh Research Explorer Mendelian Randomisation study of the influence of eGFR on coronary heart disease (2016) (0)
- Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease susceptibility and age-of-onset (2022) (0)
- P03 The Effect of Apheresis on the Donors’ Platelets (2006) (0)
- A method for fast computation of the proportion of variants affecting a complex disease and of the additive genetic variance explained in GWAS SNP studies (2014) (0)
- Proportion of idiopathic pulmonary fibrosis risk explained by known genetic loci (2020) (0)
- Adjustment for index event bias in genome-wide association studies of subsequent events (2019) (0)
- Figures Mendelian Randomisation study of the influence of eGFR on coronary heart disease (2017) (0)
- Functional Genomics of the Platelet ADP and Collagen Signalling Pathways. (2008) (0)
- Using genetic data to strengthen causal inference in observational research (2018) (0)
- A comprehensive study of candidate genes in two signalling pathways to identify genetic vaiants that regulate platelet responsiveness to collagen and ADP (2007) (0)
- Cancer Using Marker Data from Bilateral and Familial Cases Estimating Causal Effects of Genetic Risk Variants for Breast (2012) (0)
- Inaugural Lecture - Frank Dudbridge: All in the genes, or in all the genes (2015) (0)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Abstract 5693: Mesotheliomas harbor early clonal fusions involving both tumor suppressor drivers and novel oncogenic alterations (2022) (0)
- Winner’s curse, replication and meta-analysis (2016) (0)
- Comparisons Of Shrinkage Estimation Methods For Improved Prediction Of Quantitative Phenotypic Traits Related To Individual CVD Risk (2012) (0)
- A scale of interpretation for likelihood ratios and Bayes factors (2022) (0)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- On the optimal ranking of SNPs from genome-wide case-control scans (2009) (0)
- Candidate gene-environment interactions in breast cancer Spotlight on breast cancer (2020) (0)
- Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival (2020) (0)
- Author Correction: Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival (2020) (0)
- Robust tests of association for multilocus haplotypes in nuclear families (2005) (0)
- Genetic Determinants of Major Blood Lipids in Pakistan Is Compared with Europeans Running title: Saleheen et al.; Genetic loci for major lipids in Pakistan (2010) (0)
- Conditional ETDT analysis of the human leukocyte antigen region in type 1 diabetes. (2000) (0)
- The effect of variation in the GNL3 gene on bone mineral density in two populations of Caucasian women (2008) (0)
- 86 GENETIC OVERLAP BETWEEN PSYCHOTIC EXPERIENCES IN THE COMMUNITY ACROSS AGE AND WITH PSYCHIATRIC DISORDERS (2019) (0)
- Antiplatelet therapy in (cardio)vascular disease (2012) (0)
- Acknowledgement to the Reviewers (2009) (0)
- Title: Genome-wide analysis of adolescent psychotic experiences shows genetic overlap with psychiatric disorders Short title: Genome-wide analysis of psychotic experiences (2018) (0)
- Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density (2016) (0)
- P2.06-11 MEDUSA: Phylogenetic Analysis of Mesothelioma Tumours by Multiregional Sampling, Whole Exome Sequencing, and Copy Number Analysis (2019) (0)
- Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal (2013) (0)
- Investigation of genetic factors underlying specific psychotic experience traits during adolescence and their relationship with psychiatric disorders (2017) (0)
- A genome-wide association study of asthma symptoms in Latin American children (2015) (0)
- Author and Subject Index (2016) (0)
- Genetic loci for major lipids in Pakistan (2010) (0)
- Gene-by-Smoking Interaction Study on Lung Function Using a Polygenic Risk Score for COPD (0)
- Empirical Bayes factors for common hypothesis tests (2023) (0)
- MAPPING THE COMMON GENETIC ARCHITECTURE OF EARLY TEMPERAMENT: FIRST-LOOK RESULTS FROM GENOME-WIDE ASSOCIATION ANALYSES OF INFANT COHORTS (2022) (0)
- VKučinskas-2001-2016 (2016) (0)
- platelet membrane proteins inhibitory megakaryocytes and erythroblasts identifies novel activatory and Comparative gene expression profiling of in vitro differentiated (2013) (0)
- Whole-genome sequence-based analysis of thyroid function (vol 6, 5681, 2015) (2015) (0)
- susceptibility loci by Capture HiC Unbiased analysis of potential targets of breast cancer (2014) (0)
- Author Correction: Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival (2020) (0)
- Replication of newly identified genetic associations of abdominal aortic aneurysm with SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG (2020) (0)
- Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget’s disease of bone (2019) (0)
- Full Title: Fibrinogen AαThr312Ala polymorphism is associated with Chronic Thromboembolic Pulmonary Hypertension Short title: Fibrinogen AαThr312Ala in CTEPH Authors (2007) (0)
- Genome-wide analysis of psychotic-like experiences (2018) (0)
- Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) (0)
- Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents (2015) (0)
- 93. FIRST-LOOK RESULTS FROM A GENOME-WIDE ASSOCIATION META-ANALYSIS OF AGE OF LEARNING TO WALK (2022) (0)
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