Frank Kirchhoff

Frank Kirchhoff's AcademicInfluence.com Rankings

Frank Kirchhoff

Biology

#5599

World Rank

#8115

Historical Rank

Virology

#107

World Rank

#110

Historical Rank

biology Degrees

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Biology

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Frank Kirchhoff's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo (2005) (4780)
Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. (1992) (1107)
Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection (1995) (958)
Microglia: New Roles for the Synaptic Stripper (2013) (949)
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo (2004) (778)
Exosomes are released by cultured cortical neurones (2006) (769)
Neuronal or Glial Progeny Regional Differences in Radial Glia Fate (2003) (753)
Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication (2013) (644)
GFAP promoter‐controlled EGFP‐expressing transgenic mice: A tool to visualize astrocytes and astrogliosis in living brain tissue (2001) (549)
Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection (2007) (531)
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 (2020) (527)
Viscoelastic properties of individual glial cells and neurons in the CNS (2006) (508)
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. (1995) (502)
A role for glia in the progression of Rett’s syndrome (2011) (462)
Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex (2008) (455)
Segregated Expression of AMPA-Type Glutamate Receptors and Glutamate Transporters Defines Distinct Astrocyte Populations in the Mouse Hippocampus (2003) (449)
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine (2010) (429)
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. (2009) (426)
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 (2006) (419)
Nef proteins from simian immunodeficiency viruses are tetherin antagonists. (2009) (361)
NMDA Receptors Mediate Neuron-to-Glia Signaling in Mouse Cortical Astrocytes (2006) (351)
Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism (2016) (333)
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas (2021) (322)
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. (2010) (320)
Detection of SARS-CoV-2 in human breastmilk (2020) (309)
Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses. (2010) (308)
Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury (2011) (301)
Astroglial processes show spontaneous motility at active synaptic terminals in situ (2004) (284)
NMDA Receptors in Glia (2007) (263)
Glia: the fulcrum of brain diseases (2007) (261)
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. (2014) (252)
Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices (2002) (247)
High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection (1996) (246)
Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide (2007) (242)
Immunohistological localization of the adhesion molecules L1, N‐CAM, and MAG in the developing and adult optic nerve of mice (1989) (239)
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts (2009) (228)
DC-SIGN Interactions with Human Immunodeficiency Virus Type 1 and 2 and Simian Immunodeficiency Virus (2001) (227)
Morphology and dynamics of perisynaptic glia (2010) (217)
Mechanisms of ATP‐ and glutamate‐mediated calcium signaling in white matter astrocytes (2008) (205)
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP (2017) (202)
Contribution of Vpu, Env, and Nef to CD4 Down-Modulation and Resistance of Human Immunodeficiency Virus Type 1-Infected T Cells to Superinfection (2006) (201)
LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus (2005) (199)
Low levels of SIV infection in sooty mangabey central-memory CD4+ T-cells is associated with limited CCR5 expression (2011) (199)
Down-Modulation of Mature Major Histocompatibility Complex Class II and Up-Regulation of Invariant Chain Cell Surface Expression Are Well-Conserved Functions of Human and Simian Immunodeficiency Virus nef Alleles (2003) (194)
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation. (2006) (190)
Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing (2014) (189)
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. (2012) (186)
Seizures preferentially stimulate proliferation of radial glia‐like astrocytes in the adult dentate gyrus: functional and immunocytochemical analysis (2003) (183)
Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen‐inducible DNA recombinase variant CreERT2 (2006) (177)
The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection (2008) (173)
Bergmann Glial AMPA Receptors Are Required for Fine Motor Coordination (2012) (170)
Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity. (2016) (167)
Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease (2011) (166)
P2X1 and P2X5 Subunits Form the Functional P2X Receptor in Mouse Cortical Astrocytes (2008) (164)
Modulation of Different Human Immunodeficiency Virus Type 1 Nef Functions during Progression to AIDS (2001) (162)
Expression of reef coral fluorescent proteins in the central nervous system of transgenic mice (2005) (160)
Glutamate‐mediated neuronal–glial transmission (2007) (158)
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. (2011) (150)
Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development (2014) (141)
Split-Cre Complementation Indicates Coincident Activity of Different Genes In Vivo (2009) (139)
A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells (2010) (139)
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI (2010) (136)
NO mediates microglial response to acute spinal cord injury under ATP control in vivo (2010) (133)
Purification and analysis of in vivo-differentiated oligodendrocytes expressing the green fluorescent protein. (2000) (132)
AN2/NG2 protein‐expressing glial progenitor cells in the murine CNS: Isolation, differentiation, and association with radial glia (2001) (131)
Chronically CNS-Injured Adult Sensory Neurons Gain Regenerative Competence upon a Lesion of Their Peripheral Axon (2009) (129)
Pathways of neuron-astrocyte interactions and their possible role in neuroprotection (2001) (129)
Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties (2000) (129)
Role of Nef in primate lentiviral immunopathogenesis (2008) (128)
Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities (2021) (121)
Nef-Mediated Enhancement of Virion Infectivity and Stimulation of Viral Replication Are Fundamental Properties of Primate Lentiviruses (2007) (120)
Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks (2016) (117)
Sequence Variations in Human Immunodeficiency Virus Type 1 Nef Are Associated with Different Stages of Disease (1999) (116)
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. (2013) (115)
Bioactive 3D cell culture system minimizes cellular stress and maintains the in vivo‐like morphological complexity of astroglial cells (2013) (113)
Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants (2021) (109)
CD4 Down-Modulation by Human Immunodeficiency Virus Type 1 Nef Correlates with the Efficiency of Viral Replication and with CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo (2001) (105)
Nef Induces Multiple Genes Involved in Cholesterol Synthesis and Uptake in Human Immunodeficiency Virus Type 1-Infected T Cells (2005) (104)
Highly sialylated N-CAM is expressed in adult mouse optic nerve and retina (1990) (103)
Calcium microdomains in regulated exocytosis. (2006) (103)
Epidermal Growth Factor is a Motility Factor for Microglial Cells In Vitro: Evidence for EGF Receptor Expression (1997) (101)
Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques (1997) (100)
Peptide and peptide-based inhibitors of SARS-CoV-2 entry (2020) (100)
Nef Enhances Human Immunodeficiency Virus Type 1 Infectivity and Replication Independently of Viral Coreceptor Tropism (2002) (100)
Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen (2014) (99)
Host proteins involved in HIV infection: new therapeutic targets. (2010) (99)
Mouse Brain Microglia Express Interleukin-15 and Its Multimeric Receptor Complex Functionally Coupled to Janus Kinase Activity* (1997) (98)
Diversity of Functional Astroglial Properties in the Respiratory Network (2004) (97)
In Vivo Imaging of Intersynaptic Vesicle Exchange Using VGLUT1Venus Knock-In Mice (2011) (96)
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. (2000) (96)
Osteopontin attenuates aging‐associated phenotypes of hematopoietic stem cells (2017) (96)
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro (2020) (95)
Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins (2015) (95)
Enhanced CD4 Down-modulation by Late Stage HIV-1 nef Alleles Is Associated with Increased Env Incorporation and Viral Replication* (2003) (95)
Simian and Human Immunodeficiency Virus Nef Proteins Use Different Surfaces To Downregulate Class I Major Histocompatibility Complex Antigen Expression (2000) (92)
Two elements target SIV Nef to the AP‐2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis (1999) (90)
Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue (2010) (90)
MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve (2007) (89)
Tetherin: Holding On and Letting Go (2010) (89)
SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans (2020) (88)
Shapes of astrocyte networks in the juvenile brain. (2006) (88)
GABA Triggers a [Ca2+]i Increase in Murine Precursor Cells of the Oligodendrocyte Lineage (1992) (88)
SnapShot: Antiviral Restriction Factors (2015) (88)
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis (2006) (87)
Naturally Occurring Fragments from Two Distinct Regions of the Prostatic Acid Phosphatase Form Amyloidogenic Enhancers of HIV Infection (2011) (87)
Omicron: What Makes the Latest SARS-CoV-2 Variant of Concern So Concerning? (2022) (87)
Identification of the First Nonpeptidergic Inverse Agonist for a Constitutively Active Viral-encoded G Protein-coupled Receptor* (2003) (85)
Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry (1997) (84)
Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution? (2009) (84)
Implications of Nef: host cell interactions in viral persistence and progression to AIDS. (2009) (82)
Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer (2009) (81)
The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild. (2016) (80)
Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins. (2019) (80)
Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene (1994) (79)
Glutamate-triggered calcium signalling in mouse Bergmann glial cells in situ: role of inositol-1,4,5-trisphosphate-mediated intracellular calcium release (1999) (79)
Conserved Residue Lys574 in the Cavity of HIV-1 Gp41 Coiled-coil Domain Is Critical for Six-helix Bundle Stability and Virus Entry* (2007) (79)
Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses (2015) (78)
Nef proteins of epidemic HIV-1 group O strains antagonize human tetherin. (2014) (78)
Morphological and physiological interactions of NG2‐glia with astrocytes and neurons (2007) (77)
Short-Term Monotherapy in HIV-Infected Patients with a Virus Entry Inhibitor Against the gp41 Fusion Peptide (2010) (76)
Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells Is Associated with Lack of Progression in Viremic Individuals (2014) (76)
Efficient Class I Major Histocompatibility Complex Down-Regulation by Simian Immunodeficiency Virus Nef Is Associated with a Strong Selective Advantage in Infected Rhesus Macaques (2001) (75)
Nef Proteins from Diverse Groups of Primate Lentiviruses Downmodulate CXCR4 To Inhibit Migration to the Chemokine Stromal Derived Factor 1 (2005) (74)
Aminoquinoline Surfen Inhibits the Action of SEVI (Semen-derived Enhancer of Viral Infection)* (2009) (74)
Human Immunodeficiency Virus Type 1 Inhibits DNA Damage-Triggered Apoptosis by a Nef-Independent Mechanism (2005) (73)
Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance (2016) (72)
DC-SIGN Interactions with Human Immunodeficiency Virus: Virus Binding and Transfer Are Dissociable Functions (2001) (72)
Emerging role of the host restriction factor tetherin in viral immune sensing. (2013) (72)
Disrupting Surfaces of Nef Required for Downregulation of CD4 and for Enhancement of Virion Infectivity Attenuates Simian Immunodeficiency Virus Replication In Vivo (2000) (71)
Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host (2018) (71)
Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu Protein (2012) (69)
Cytopathicity of Human Immunodeficiency Virus Type 2 (HIV-2) in Human Lymphoid Tissue Is Coreceptor Dependent and Comparable to That of HIV-1 (2000) (69)
HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef (2011) (69)
Normal immune function and inability to isolate virus in culture in an individual with long-term human immunodeficiency virus type 1 infection. (1994) (68)
Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia (2018) (68)
Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses (2018) (67)
Inefficient Nef-Mediated Downmodulation of CD3 and MHC-I Correlates with Loss of CD4+ T Cells in Natural SIV Infection (2008) (67)
A Protein Kinase Activity Is Associated with and Specifically Phosphorylates the Neural Cell Adhesion Molecule LI (1989) (67)
A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (65)
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies (2015) (65)
In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS (2011) (65)
Long-term nonprogressive infection with human immunodeficiency virus type 1 in a hemophilia cohort. (1999) (64)
Three‐dimensional confocal morphometry reveals structural changes in astrocyte morphology in situ (2007) (64)
Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression. (2013) (64)
HIV Triggers a cGAS-Dependent, Vpu- and Vpr-Regulated Type I Interferon Response in CD4+ T Cells. (2016) (63)
Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides (2014) (63)
Monkeypox: A New Threat? (2022) (63)
Discovery and characterization of an endogenous CXCR4 antagonist. (2015) (63)
Experimental infection of macaques with HIV-2ben, a novel HIV-2 isolate. (1990) (62)
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation. (2019) (62)
Expression of Glycine Receptor Subunits in Glial Cells of the Rat Spinal Cord (1996) (62)
Coreceptor usage of BOB/GPR15 and Bonzo/STRL33 by primary isolates of human immunodeficiency virus type 1. (1999) (62)
The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses. (2009) (61)
Kainate activates Ca2+-permeable glutamate receptors and blocks voltage-gated K+ currents in glial cells of mouse hippocampal slices (1994) (61)
CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry. (2011) (61)
Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways (2017) (61)
Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-γ and tumor necrosis factor-α affects neurite outgrowth (1991) (60)
Kir4.1 channels regulate swelling of astroglial processes in experimental spinal cord edema (2007) (59)
Bone Marrow-Derived Cells Expressing Green Fluorescent Protein under the Control of the Glial Fibrillary Acidic Protein Promoter Do Not Differentiate into Astrocytes In Vitro and In Vivo (2003) (58)
Nef Proteins from Simian Immunodeficiency Virus-Infected Chimpanzees Interact with p21-Activated Kinase 2 and Modulate Cell Surface Expression of Various Human Receptors (2004) (57)
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection (2021) (57)
Key Viral Adaptations Preceding the AIDS Pandemic. (2019) (55)
Liquefaction of Semen Generates and Later Degrades a Conserved Semenogelin Peptide That Enhances HIV Infection (2014) (55)
Vpr and Vpu Are Important for Efficient Human Immunodeficiency Virus Type 1 Replication and CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo (2004) (54)
The "V3" domain is a determinant of simian immunodeficiency virus cell tropism (1994) (53)
Three‐dimensional confocal morphometry – a new approach for studying dynamic changes in cell morphology in brain slices (2007) (53)
CD4+ T Cell–Derived IL-21 and Deprivation of CD40 Signaling Favor the In Vivo Development of Granzyme B–Expressing Regulatory B Cells in HIV Patients (2015) (53)
Co-receptor usage of BOB/GPR15 in addition to CCR5 has no significant effect on replication of simian immunodeficiency virus in vivo. (1999) (50)
Selective downmodulation of HLA-A and -B by Nef alleles from different groups of primate lentiviruses. (2008) (50)
Expression and functional analysis of glutamate receptors in glial cells. (1999) (49)
Nef Associates with p21-Activated Kinase 2 in a p21-GTPase-Dependent Dynamic Activation Complex within Lipid Rafts (2004) (48)
Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. (2010) (48)
Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles. (2018) (48)
Semen amyloids participate in spermatozoa selection and clearance (2017) (48)
Evidence for the cooperation of gp120 amino acids 322 and 448 in SIVmac entry. (1993) (48)
Partial "repair" of defective NEF genes in a long-term nonprogressor with human immunodeficiency virus type 1 infection. (2000) (48)
Manipulation of autophagy by SARS-CoV-2 proteins (2021) (46)
Is Nef the elusive cause of HIV-associated hematopoietic dysfunction? (2008) (46)
Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins. (2018) (45)
Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation. (2012) (45)
Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells (2016) (45)
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses (2019) (45)
Bergmann glial cells in situ express endothelinB receptors linked to cytoplasmic calcium signals. (1997) (45)
Primary Sooty Mangabey Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2 nef Alleles Modulate Cell Surface Expression of Various Human Receptors and Enhance Viral Infectivity and Replication (2005) (44)
Human Immunodeficiency Virus Type 1 Variants Resistant to First- and Second-Version Fusion Inhibitors and Cytopathic in Ex Vivo Human Lymphoid Tissue (2007) (43)
Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors (1999) (43)
N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation (2019) (43)
The Human Immunodeficiency Virus Type 1nef Gene Can to a Large Extent Replace Simian Immunodeficiency Virus nef In Vivo (1999) (42)
Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus (2013) (42)
90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1 (2013) (42)
Simian Immunodeficiency Virus Utilizes Human and Sooty Mangabey but Not Rhesus Macaque STRL33 for Efficient Entry (2000) (41)
Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons (2018) (41)
Effect of R77Q, R77A and R80A changes in Vpr on HIV-1 replication and CD4 T cell depletion in human lymphoid tissue ex vivo (2006) (41)
CpG Frequency in the 5′ Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein (2020) (41)
Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry (2012) (40)
Influence of Methylene Blue on Microglia-Induced Inflammation and Motor Neuron Degeneration in the SOD1G93A Model for ALS (2012) (40)
Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host. (2012) (40)
Association of Nef with p21-Activated Kinase 2 Is Dispensable for Efficient Human Immunodeficiency Virus Type 1 Replication and Cytopathicity in Ex Vivo-Infected Human Lymphoid Tissue (2007) (39)
Microglia: first responders in the central nervous system. (2013) (38)
Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4+ T Cell Counts in Viremic HIV-2 Infection (2012) (38)
Detecting fluorescent protein expression and co-localisation on single secretory vesicles with linear spectral unmixing (2006) (38)
Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis (2014) (37)
HIV-1 Vpu Does Not Degrade Interferon Regulatory Factor 3 (2013) (37)
BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity (2017) (36)
CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling (2009) (36)
Hemofiltrate CC Chemokine 1[9-74] Causes Effective Internalization of CCR5 and Is a Potent Inhibitor of R5-Tropic Human Immunodeficiency Virus Type 1 Strains in Primary T Cells and Macrophages (2002) (36)
Ancient origin of a deletion in human BST2/Tetherin that confers protection against viral zoonoses (2011) (36)
An optimized MM/PBSA virtual screening approach applied to an HIV‐1 gp41 fusion peptide inhibitor (2011) (35)
Simian Immunodeficiency Virus Containing Mutations in N-Terminal Tyrosine Residues and in the PxxP Motif in Nef Replicates Efficiently in Rhesus Macaques (2000) (35)
Genetic Identity and Biological Phenotype of a Transmitted/Founder Virus Representative of Nonpathogenic Simian Immunodeficiency Virus Infection in African Green Monkeys (2010) (35)
A novel proviral clone of HIV-2: biological and phylogenetic relationship to other primate immunodeficiency viruses. (1990) (35)
HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation (2018) (35)
Myelin‐associated glycoprotein is phosphorylated by protein kinase C (1993) (34)
The Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses (2010) (34)
A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes. (2007) (34)
Activity of human immunodeficiency virus type 1 promoter/TAR regions and tat1 genes derived from individuals with different rates of disease progression. (1997) (34)
Comprehensive Analysis of Nef Functions Selected in Simian Immunodeficiency Virus-Infected Macaques (2004) (33)
Enteric Glia: S100, GFAP, and Beyond (2019) (33)
HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression (2020) (33)
Endothelin‐induced calcium signaling in cultured mouse microglial cells is mediated through ETB receptors (1997) (33)
Long‐lasting post‐mortem activity of spinal microglia in situ in mice (2010) (32)
Amino Acid 324 in the Simian Immunodeficiency Virus SIVmac V3 Loop Can Confer CD4 Independence and Modulate the Interaction with CCR5 and Alternative Coreceptors (2004) (32)
Sequences Just Upstream of the Simian Immunodeficiency Virus Core Enhancer Allow Efficient Replication in the Absence of NF-κB and Sp1 Binding Elements (1998) (32)
CD4 Binding Affinity Determines Human Immunodeficiency Virus Type 1-Induced Alpha Interferon Production in Plasmacytoid Dendritic Cells (2008) (32)
Discovery of modulators of HIV-1 infection from the human peptidome (2014) (32)
HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells. (2017) (32)
Effect of naturally-occurring gp41 HR1 variations on susceptibility of HIV-1 to fusion inhibitors (2005) (32)
HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A. (2013) (31)
Systematic colocalization errors between acridine orange and EGFP in astrocyte vesicular organelles. (2007) (31)
T-Cell Receptor:CD3 Down-Regulation Is a Selected In Vivo Function of Simian Immunodeficiency Virus Nef but Is Not Sufficient for Effective Viral Replication in Rhesus Macaques (2002) (31)
Genetic control of astrocyte function in neural circuits (2015) (31)
Early Vertebrate Evolution of the Host Restriction Factor Tetherin (2015) (30)
Current technical approaches to brain energy metabolism (2018) (30)
Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells (2015) (29)
Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells (2012) (29)
Guanylate binding protein 5: Impairing virion infectivity by targeting retroviral envelope glycoproteins (2016) (29)
Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo. (2018) (29)
Expression of Multidrug Resistance Proteins (Mrps) in Astrocytes of the Mouse Brain: A Single Cell RT-PCR Study (2005) (28)
Counteraction of HLA-C-Mediated Immune Control of HIV-1 by Nef (2010) (28)
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 (2021) (28)
Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation (2017) (28)
Early embryonic NG2 glia are exclusively gliogenic and do not generate neurons in the brain (2019) (27)
Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques (2006) (27)
During Development NG2 Glial Cells of the Spinal Cord are Restricted to the Oligodendrocyte Lineage, but Generate Astrocytes upon Acute Injury (2018) (27)
Silencing HIV-1 In Vivo (2008) (26)
HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner (2020) (26)
Identification of neuropeptide Y receptors in cultured astrocytes from neonatal rat brain (1993) (26)
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation (2021) (26)
Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors (2007) (26)
HIV replication: a game of hide and sense (2016) (26)
Peptide nanofibrils as enhancers of retroviral gene transfer. (2014) (25)
Selective Downregulation of Rhesus Macaque and Sooty Mangabey Major Histocompatibility Complex Class I Molecules by Nef Alleles of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2 (2008) (25)
Interferons and beyond: Induction of antiretroviral restriction factors (2017) (24)
The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site (2020) (24)
Structural basis for tetherin antagonism as a barrier to zoonotic lentiviral transmission (2019) (24)
Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression (2017) (24)
Isolation and characterization of HIV-2ben obtained from a patient with predominantly neurological defects. (1990) (24)
A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release (2013) (24)
The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals (2013) (23)
Exploiting the human peptidome for novel antimicrobial and anticancer agents. (2017) (23)
Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3 (2017) (23)
Single-cell characterization of endothelin system gene expression in the cerebellum in situ. (1998) (22)
Disrupting Surfaces of Nef Required for Downregulation of CD4 and for Enhancement of Virion Infectivity Attenuates Simian Immunodeficiency Virus Replication In Vivo (2000) (22)
Inhibition of HIV-1 group M and O isolates by fusion inhibitors (2005) (22)
The most frequent naturally occurring length polymorphism in the HIV-1 LTR has little effect on proviral transcription and viral replication. (2002) (22)
A protein kinase activity is associated with and specifically phosphorylates the neural cell adhesion molecule L1. (1989) (22)
Effects of mutations in constant regions 3 and 4 of envelope of simian immunodeficiency virus. (1995) (22)
Alterations in HIV-1 LTR promoter activity during AIDS progression. (2003) (21)
Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice (2007) (21)
Genetic Background Affects Human Glial Fibrillary Acidic Protein Promoter Activity (2013) (21)
Endocannabinoids and Heterogeneity of Glial Cells in Brain Function (2016) (21)
Mutations in the C3 region of human and simian immunodeficiency virus envelope have differential effects on viral infectivity, replication, and CD4-dependency. (2003) (21)
The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K Is Species Specific (2018) (21)
Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection (2015) (21)
A Placenta Derived C-Terminal Fragment of β-Hemoglobin With Combined Antibacterial and Antiviral Activity (2020) (21)
Genomic divergence of an HIV-2 from a German AIDS patient probably infected in Mali. (1990) (20)
The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function (2013) (20)
TRPC1‐ and TRPC3‐dependent Ca2+ signaling in mouse cortical astrocytes affects injury‐evoked astrogliosis in vivo (2017) (20)
Evaluation of TgH(CX3CR1-EGFP) mice implanted with mCherry-GL261 cells as an in vivo model for morphometrical analysis of glioma-microglia interaction (2016) (20)
The Transmembrane Protease TMPRSS2 as a Therapeutic Target for COVID-19 Treatment (2022) (20)
Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression (2019) (20)
Sandwich enzyme-linked immunosorbent assay for the quantification of human serum albumin fragment 408-423 in bodily fluids. (2015) (20)
The Paradox of Astroglial Ca2 + Signals at the Interface of Excitation and Inhibition (2020) (19)
Functional Topography of the Myelin‐associated Glycoprotein. I. Mapping of Domains by Electron Microscopy (1993) (19)
Human Immunodeficiency Virus Type 1 Nef Expression Prevents AP-2-Mediated Internalization of the Major Histocompatibility Complex Class II-Associated Invariant Chain (2008) (19)
Osteopontin attenuates aging‐associated phenotypes of hematopoietic stem cells (2017) (19)
Alpha-1 antitrypsin inhibits SARS-CoV-2 infection (2020) (19)
An improved method for high-throughput quantification of autophagy in mammalian cells (2020) (19)
Transactivation of Naturally Occurring HIV-1 Long Terminal Repeats by the JNK Signaling Pathway (2000) (19)
HIV infection in a patient with alpha-1 antitrypsin deficiency: a detrimental combination? (2007) (19)
Determinants of Spike infectivity, processing, and neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2 (2022) (18)
Low levels of SIV infection in sooty mangabey central memory CD4 + T cells are associated with limited (2011) (18)
Effect of the Attenuating Deletion and of Sequence Alterations Evolving In Vivo on Simian Immunodeficiency Virus C8-Nef Function (1999) (18)
IFITM proteins promote SARS-CoV-2 infection of human lung cells (2020) (18)
SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity (2021) (18)
Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment (2019) (18)
SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue (2018) (18)
EPI-X4, a novel endogenous antagonist of CXCR4 (2015) (17)
Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity (2018) (17)
The Zinc Finger Antiviral Protein restricts SARS-CoV-2 (2020) (17)
Panglial gap junctions between astrocytes and olfactory ensheathing cells mediate transmission of Ca2+ transients and neurovascular coupling (2019) (17)
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells (2020) (17)
Alternative splicing of mouse IL-15 is due to the use of an internal splice site in exon 5. (1998) (17)
Down-Modulation of CD8αβ Is a Fundamental Activity of Primate Lentiviral Nef Proteins (2011) (17)
Idiotypic vaccine for treatment of human B-cell lymphoma. Construction of IgG variable regions from single malignant B cells. (1997) (17)
HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells (2020) (16)
In vivo imaging reveals rapid morphological reactions of astrocytes towards focal lesions in an ALS mouse model (2011) (16)
The acidic region and conserved putative protein kinase C phosphorylation site in Nef are important for SIV replication in rhesus macaques. (1999) (16)
Spike residue 403 affects binding of coronavirus spikes to human ACE2 (2021) (16)
Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-gamma and tumor necrosis factor-alpha affects neurite outgrowth. (1991) (16)
Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma (2015) (16)
The role of upstream U3 sequences in HIV-1 replication and CD4+ T cell depletion in human lymphoid tissue ex vivo. (2005) (16)
Tetherin antagonism by primate lentiviral nef proteins. (2011) (15)
An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation (2020) (15)
Proline 35 of Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Regulates the Integrity of the N-Terminal Helix and the Incorporation of Vpr into Virus Particles and Supports the Replication of R5-Tropic HIV-1 in Human Lymphoid Tissue Ex Vivo (2007) (15)
Cellular Factors Targeting HIV-1 Transcription and Viral RNA Transcripts (2020) (15)
Conservation of Nef function across highly diverse lineages of SIVsmm (2009) (15)
Surgical procedures to study microglial motility in the brain and in the spinal cord by in vivo two-photon laser-scanning microscopy. (2014) (15)
Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain (2017) (15)
Involvement of a C-terminal motif in the interference of primate lentiviral Vpu proteins with CD1d-mediated antigen presentation (2015) (14)
Selection of the R17Y substitution in SIVmac239 nef coincided with a dramatic increase in plasma viremia and rapid progression to death. (1999) (14)
The Role of the Oligodendrocyte Lineage in Acute Brain Trauma (2017) (14)
In vivo two-photon imaging of motoneurons and adjacent glia in the ventral spinal cord (2018) (14)
Basic amino acid residues in the V3 loop of simian immunodeficiency virus envelope alter viral coreceptor tropism and infectivity but do not allow efficient utilization of CXCR4 as entry cofactor. (2001) (13)
Phenotype and distribution pattern of nestin-GFP-expressing cells in murine myenteric plexus (2016) (13)
Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals (2017) (13)
Lentiviral Nef Proteins Manipulate T Cells in a Subset-Specific Manner (2014) (13)
Effects of Lectins on CCK-8–Stimulated Enzyme Secretion and Differentiation of the Rat Pancreatic Cell Line AR42J (2001) (13)
Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1 (2020) (13)
Interferon antagonists encoded by SARS-CoV-2 at a glance (2022) (12)
CX3CR1 Disruption Differentially Influences Dopaminergic Neuron Degeneration in Parkinsonian Mice Depending on the Neurotoxin and Route of Administration (2016) (12)
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2 (2018) (12)
Antibody response to the negative regulatory factor (nef) in experimentally infected macaques: correlation with viremia, disease progression, and seroconversion to structural viral proteins. (1991) (12)
Differential Control of BST2 Restriction and Plasmacytoid Dendritic Cell Antiviral Response by Antagonists Encoded by HIV-1 Group M and O Strains (2016) (12)
Transgenic expression of fluorescent proteins in respiratory neurons (2007) (12)
Morphogenesis of recombinant HIV-2 gag core particles. (1992) (12)
Link between Primate Lentiviral Coreceptor Usage and Nef Function (2013) (11)
Simian Immunodeficiency Virus in Which nef and U3 Sequences Do Not Overlap Replicates Efficiently In Vitro and In Vivo in Rhesus Macaques (2001) (11)
Molecular Control of HIV and SIV Latency. (2017) (11)
Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions (2014) (11)
Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins (2021) (11)
Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses (2019) (11)
SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells (2022) (11)
Combined two-photon laser-scanning microscopy and spectral microCT X-ray imaging to characterize the cellular signature and evolution of microstroke foci. (2012) (11)
Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels (2015) (11)
Sublamina‐specific organization of the blood brain barrier in the mouse olfactory nerve layer (2019) (11)
Detection of SARS-CoV-2 in Human Breast Milk (2020) (10)
Serotonin receptor 4 regulates hippocampal astrocyte morphology and function (2020) (10)
Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model (2019) (10)
Enrichment and isolation of neurons from adult mouse brain for ex vivo analysis (2017) (10)
In vivo two-photon imaging of neurons and glia in the mouse spinal cord. (2012) (10)
Role of MHC-I Expression on Spinal Motoneuron Survival and Glial Reactions Following Ventral Root Crush in Mice (2019) (10)
The inhibitory input to mouse cerebellar Purkinje cells is reciprocally modulated by Bergmann glial P2Y1 and AMPA receptor signaling (2016) (10)
BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults (2022) (9)
Pen-2 Negatively Regulates the Differentiation of Oligodendrocyte Precursor Cells into Astrocytes in the Central Nervous System (2021) (9)
Oligodendroglial GABAergic Signaling: More Than Inhibition! (2021) (9)
First Steps toward a Globally Effective HIV/AIDS Vaccine (2013) (9)
Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Boosts Neutralizing Activity Against Seasonal Human Coronaviruses (2022) (9)
SIVmac expressing hybrid envelope proteins containing HIV-1 V3 and/or C4 sequences is not competent for replication. (1994) (8)
A Naturally Occurring Variation in the Proline-Rich Region Does Not Attenuate Human Immunodeficiency Virus Type 1 Nef Function (2004) (8)
The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4+ T cells (2021) (8)
Inhibitory Effect of the Lectin Wheat Germ Agglutinin on the Binding of 125I-CCK-8s to the CCK-A and -B Receptors of AR42J Cells (2004) (8)
Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior (2021) (8)
Questionable Calcium (2010) (8)
The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells (2021) (7)
Analysis of Functional NMDA Receptors in Astrocytes. (2017) (7)
Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages (2021) (7)
Actin cytoskeleton remodeling primes RIG-I-like receptor activation (2022) (7)
Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ (2020) (7)
Synthesis of Peptide-Functionalized Poly(bis-sulfone) Copolymers Regulating HIV-1 Entry and Cancer Stem Cell Migration. (2017) (7)
Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (7)
A PCR-derived library of random point mutations within the V3 region of simian immunodeficiency virus. (1993) (7)
Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread (2020) (7)
Computational modeling and experimental validation of the EPI-X4/CXCR4 complex allows rational design of small peptide antagonists (2021) (7)
When good turns bad: how viruses exploit innate immunity factors (2022) (7)
Identification of V3 mutations that can compensate for inactivating mutations in C4 of simian immunodeficiency virus. (1995) (6)
From Physiology to Pathology of Cortico-Thalamo-Cortical Oscillations: Astroglia as a Target for Further Research (2021) (6)
Glial heterogeneity: the increasing complexity of the brain (2015) (6)
Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs (2018) (6)
Evolutionary conflicts and adverse effects of antiviral factors (2021) (6)
Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms (2013) (6)
Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2 (2020) (6)
Frequencies of lymphoid T‐follicular helper cells obtained longitudinally by lymph node fine‐needle aspiration correlate significantly with viral load in SIV‐infected rhesus monkeys (2015) (6)
Imaging neuroinflammation after brain injuries by ultrasensitive MRI and two-photon laser-scanning microscopy. (2014) (6)
Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion (2020) (6)
SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles (2021) (5)
Differential regulation of human immunodeficiency virus type 2 and simian immunodeficiency virus promoter activity. (2004) (5)
Epigenetic control of region‐specific transcriptional programs in mouse cerebellar and cortical astrocytes (2021) (5)
Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins (2021) (5)
CD 95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling (2009) (5)
Simian Immunodeficiency Virus Utilizes Human and Sooty Mangabey but Not Rhesus Macaque STRL 33 for Efficient Entry (2000) (5)
Expression of myelin-associated glycoprotein transcripts in murine oligodendrocytes (1997) (4)
Astrocytes and Microglia Exhibit Cell-Specific Ca2+ Signaling Dynamics in the Murine Spinal Cord (2022) (4)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction (2020) (4)
Generation and Characterization of Virus-Enhancing Peptide Nanofibrils Functionalized with Fluorescent Labels. (2017) (4)
Properties of Human and Simian Immunodeficiency Viruses (2014) (4)
Blocking semen-mediated enhancement of HIV infection by amyloid-binding small molecules (2011) (4)
Spike mutation T403R allows bat coronavirus RaTG13 to use human ACE2 (2021) (4)
Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4+ T Cell (2021) (4)
In Vitro Evaluation of a Peptide-Mesoporous Silica Nanoparticle Drug Release System against HIV-1 (2020) (4)
Virology under the Microscope—a Call for Rational Discourse (2023) (4)
Native and activated antithrombin inhibits TMPRSS2 activity and SARS‐CoV‐2 infection (2022) (4)
90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1 (2013) (4)
Increased in vitro Anti‐HIV Activity of Caffeinium‐Functionalized Polyoxometalates (2021) (4)
Versatile Surface Electrodes for Combined Electrophysiology and Two-Photon Imaging of the Mouse Central Nervous System (2021) (4)
Preparation of the mouse spinal column for single imaging using two-photon laser-scanning microscopy. (2012) (3)
IFI16 knockdown in primary HIV-1 target cells (2020) (3)
Elucidating regulators of astrocytic Ca2+ signaling via multi‐threshold event detection (MTED) (2021) (3)
Interaction of Glia Cells with Glioblastoma and Melanoma Cells under the Influence of Phytocannabinoids (2022) (3)
HIV-1 Resistance to Fusion Inhibitors (2007) (3)
A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo. (2007) (3)
Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling (2020) (3)
SEVI and Semen Impair the Anti-HIV-1 Activity of Drugs and Microbicides (2009) (3)
Axel Nimmerjahn Parenchyma in Vivo Resting Microglial Cells Are Highly Dynamic Surveillants of Brain (2013) (3)
L-Type Ca2+ Channels of NG2 Glia Determine Proliferation and NMDA Receptor-Dependent Plasticity (2021) (3)
Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques (2019) (3)
The negative (?) factor of HIV and SIV. (1992) (3)
HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells (2022) (3)
High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection (2022) (2)
IFITMs: Important Factors In Trans-Mission of HIV-1. (2016) (2)
Real-Time Killing Assays to Assess the Potency of a New Anti-Simian Immunodeficiency Virus Chimeric Antigen Receptor T Cell (2020) (2)
Author response: HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses (2019) (2)
, Surveillants of Brain Parenchyma in Vivo Resting Microglial Cells Are Highly Dynamic (2010) (2)
Preparation of the mouse spinal column for repetitive imaging using two-photon laser-scanning microscopy. (2012) (2)
Emerging Role of PYHIN Proteins as Antiviral Restriction Factors (2020) (2)
A fast perfusion system for single cell physiology optimized for microscopes with water immersion objectives (1992) (2)
SARS-CoV-2 infection and the brain: direct evidence for brain changes in milder cases (2022) (2)
Astrocyte Intracellular Ca2+and TrkB Signaling in the Hippocampus Could Be Involved in the Beneficial Behavioral Effects of Antidepressant Treatment (2021) (2)
Purinergic activation of dorsal root ganglion neurones in vivo (2011) (2)
HIV-1 accessory proteins: Nef. (2014) (2)
Author response: Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks (2016) (2)
Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+ T cell depletion in natural SIV infection (2006) (2)
Real-time killing assays to assess the potency of a new anti-SIV CAR. (2020) (2)
Lymphocryptovirus-dependent occurrence of lymphoma in SIV-infected rhesus macaques with particular consideration to two uncommon cases of non-Hodgkin's lymphoma (2016) (2)
HIV-1 Vpu restricts Fc-mediated effector functions in vivo (2022) (2)
CRISPA: A Non-viral, Transient Cas9 Delivery System Based on Reengineered Anthrax Toxin (2021) (2)
A Novel Glycine Receptor β Subunit Splice Variant Predicts an Unorthodox Transmembrane Topology (2007) (2)
Natural SIV Infection (2012) (2)
Potential roles of Nef and Vpu in HIV-1 latency (2019) (2)
Virology under the Microscope—a Call for Rational Discourse (2023) (1)
Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide (2011) (1)
Random mutagenesis of short target DNA sequences via PCR with degenerate oligonucleotides. (1996) (1)
immunodeficiency virus cell tropism. The "V3" domain is a determinant of simian (2014) (1)
Alix is required for activity-dependent bulk endocytosis at brain synapses (2020) (1)
HIV triggers interleukin 21-mediated induction of granzyme B-secreting B cells with antiviral properties (105.18) (2012) (1)
The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals (2013) (1)
SARS-CoV-2 infects cells of the human exocrine and endocrine pancreas and interferes with beta-cell function (2020) (1)
Angiotensin-Receptor-Associated Protein Modulates Ca2+ Signals in Photoreceptor and Mossy Fiber cells (2019) (1)
Species-specific differences in antagonism of APOBEC3 proteins by HIV-2 and SIVsmm Vif proteins (2020) (1)
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques (2022) (1)
Systematic analysis of innate immune antagonism reveals vulnerabilities of SARS-CoV-2 (2020) (1)
Serially passaged, conditionally reprogrammed nasal epithelial cells as a model to study epithelial functions and SARS-CoV-2 infection (2022) (1)
Glue or goo? mechanical properties of glial cells and neurons in the CNS (2006) (1)
Strong attenuation of SARS-CoV-2 Omicron BA.1 and increased replication of the BA.5 subvariant in human cardiomyocytes (2022) (1)
Semen-mediated enhancement of HIV-1 infection markedly impairs the antiviral efficacy of microbicides (1)
APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans (2021) (1)
Inhibition Of Airway Inflammation And HIV Entry By NNY-CCL14 Treatment: Role Of CCR1 And CCR5 (2007) (1)
Deciphering spatio-temporal fluorescence changes using multi-threshold event detection (MTED) (2020) (1)
Forssmann Inhibitor Against the gp 41 Fusion Peptide Short-Term Monotherapy in HIV-Infected Patients with a Virus Entry (2010) (1)
Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity (2021) (1)
Modular Hydrogel−Mesoporous Silica Nanoparticle Constructs for Therapy and Diagnostics (2021) (1)
HIV protease: late action to prevent immune detection (2021) (1)
HIV-1 Nefs are cargo-sensitive AP-1 trimerization switches in tetherin and MHC-I downregulation (2018) (1)
Undermining breastfeeding will not alleviate the COVID-19 pandemic – Authors' reply (2020) (1)
Role of Microglia in the Normal Brain (2012) (1)
Track A Basic Science (2012) (1)
Imaging analysis of oligodendrocytes during myelination and trauma in living brain tissue of PLP-DsRED mice (2002) (1)
Virology under the Microscope—a Call for Rational Discourse (2023) (1)
After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes (2021) (1)
Tetherin antagonism by HIV-1 and its SIV precursors (2011) (1)
HIV triggers interleukin 21-mediated induction of granzyme B-secreting B cells with T cell regulatory potential. (P1441) (2013) (1)
Counteraction of the antiviral factor tetherin by HIV-1 Group O (2017) (1)
Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease (2011) (1)
Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage (2021) (1)
Decrease in newly generated oligodendrocytes leads to changed myelin structures and motor dysfunctions that are rescued by transplanted cells. (2017) (0)
Osteopontin regulates and attenuates aging-associated phenotypes of HSCS (2016) (0)
Detection of gag-Specific Cytotoxic T Lymphocytes in HIV-2ben-Infected Macaques (1992) (0)
Expression of a glial potassium channel in the developing cerebellum and impact of its genetic inactivation on neuronal cell survival (2006) (0)
Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus (2013) (0)
SARS-CoV-2 vaccination of convalescents boosts neutralization capacity against Omicron subvariants BA.1, BA.2 and BA.5 and can be predicted by anti-S antibody concentrations in serological assays (2023) (0)
A peptide for the treatment of herpes virus infections (2005) (0)
Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis (2013) (0)
NG(2) glia in health and disease: axon-glial interactions and neurotransmitter-mediated calcium signalling in CNS white matter (2007) (0)
Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3 (2017) (0)
Decision letter: Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection (2019) (0)
Enhancement of HIV Infection by semen (2009) (0)
Regain of Nef-mediated tetherin antagonism in a chimpanzee experimentally infected with HIV-1 (2013) (0)
GABAergic signaling to NG2 glia in de- and re-myelination (2019) (0)
Decision letter: ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology (2021) (0)
CD4 Binding Afﬁnity Determines Human Immunodeﬁciency Virus Type 1-Induced Alpha Interferon Production in Plasmacytoid Dendritic Cells (cid:1) (2008) (0)
Editor's evaluation: Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis (2021) (0)
Decision letter: Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis (2021) (0)
The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function (2013) (0)
Thomas Mertens Role of the accessory Vpr and Vpu proteins and upstream LTR U 3 sequences in HIV-1 replication and cytopathicity in human lymphoid tissue ex vivo (2007) (0)
Author response: A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (0)
Enhancers of HIV Infection Phosphatase Form Amyloidogenic Distinct Regions of the Prostatic Acid Naturally Occurring Fragments from Two (2011) (0)
Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (0)
Explorer Synaptic pathology at the neuromuscular junction in a mouse model of childhood motor neuron disease ( spinal muscular atrophy ) (2016) (0)
Peptides for treating infections with herpes virus (2005) (0)
Human Immunodeﬁciency Virus Type 1 Variants Resistant to First- and Second-Version Fusion Inhibitors and Cytopathic in Ex Vivo Human Lymphoid Tissue (cid:1) (2007) (0)
Identification of potential HIV restriction factors by combining evolutionary signatures with functional analyses (0)
A: Principle of split-Cre complementation. (2009) (0)
The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeﬁciency Virus Infection (cid:1) (2008) (0)
Pathogenicity in Rhesus Macaques Immunodeficiency Virus Replication and Element in Nef for Simian Importance of the N-Distal AP-2 Binding (2006) (0)
Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages (2019) (0)
Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms (2013) (0)
Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2 (2023) (0)
Neuroprotective Effects of Cannabidiol Under Cerebral Ischemic Conditions (2021) (0)
Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis (2013) (0)
Somatodendritic and axonal uptake of exosomes. (2013) (0)
Determinants of species-specific utilization of ACE2 by human and animal coronaviruses (2023) (0)
IL-21-Mediated Generation of Human Regulatory B Cells Occurs Independently of CD40 Signaling (2014) (0)
Dysfunction of grey matter NG2 glial cells affects neuronal plasticity and behavior (2021) (0)
HIV-Infected T Cells Induce Granzyme B-Secreting Regulatory B Cells in An Interleukin 21-Dependent Fashion, (2011) (0)
A critical role for the Kir4.1 channel subtype in setting the membrane potential of optic nerve glia (2007) (0)
Characterization of 90 K / LGALS 3 BP as antiviral factor (0)
Mimetic Sensitization of HIV-1-infected cells to 1 ADCC 2 3 4 (2017) (0)
HIV Triggers a cGAS-Depe ndent , Vpu-and Vpr-Regulated Type I InterferonResponse inCD 4 + TCells Graphical Abstract Highlights (0)
An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins (2021) (0)
In vivo laser scanning microscopy of transgenic mice expressing cell-specific fluorescent proteins to study acute and chronic spinal cord diseases (2006) (0)
Sandwich ELISA for the quantification of human serum albumin fragment 408-423 ( hSA 408-423 ) in bodily fluids (2015) (0)
Chapter 2 Surgical Procedures to Study Microglial Motility in the Brain and in the Spinal Cord by In Vivo Two-Photon Laser-Scanning Microscopy (2019) (0)
IFITM dependency of SARS-CoV-2 variants of concern (2021) (0)
Rhesus Macaques Sufficient for Effective Viral Replication in Immunodeficiency Virus Nef but Is Not Selected In Vivo Function of Simian T-Cell Receptor:CD3 Down-Regulation Is a (2014) (0)
Longitudinal SARS-CoV-2 infection study at Ulm University (2021) (0)
Combating HIV: what the human peptidome offers (2016) (0)
Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses (2015) (0)
Decision letter: Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus (2019) (0)
Astrocytes play an essential role in reversing respiratory disturbances in a mouse model of Rett syndrome (2010) (0)
SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells (2021) (0)
Characterization of 90K/LGALS3BP as antiviral factor (2014) (0)
HIV Triggers Interleukin 21-Mediated Induction of Granzyme B-Secreting B Cells with Regulatory and Antiviral Potential (2012) (0)
A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release (2013) (0)
Review for "IP 3 R2 null mice display a normal acquisition of somatic and neurological development milestones" (2020) (0)
REDUCTION OF FIBRONECTIN EXPRESSION DECREASES OLIGODENDROCYTE LINEAGE CELL NUMBERS IN DEMYELINATION, BUT DOES NOT IMPAIR CNS REMYELINATION (2011) (0)
P2X7 knock-out mice exhibit decreased ATP and glutamate mediated calcium signalling in white matter astrocytes: implications for astroglial communication (2007) (0)
Decision letter: Predictors of SIV recrudescence following antiretroviral treatment interruption (2019) (0)
Neuroprotective role of oligodendroglial exosomes. (2013) (0)
Microglial contribution to neurodegeneration within the CNS and inflammation-independent degeneration within the PNS in the SOD1 (G93A) mouse model for ALS – a 2P-LSM study in vivo (2010) (0)
NOTES Nef Induces Multiple Genes Involved in Cholesterol Synthesis and Uptake in Human Immunodeﬁciency Virus Type 1-Infected T Cells (2005) (0)
The fate of B cells in HIV infection - shifting the balance from plasma cell towards regulatory B cell (Breg) differentiation (LYM6P.776) (2014) (0)
Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions (2014) (0)
Editor's evaluation: ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology (2021) (0)
Biographical Feature: Bernhard Fleckenstein (2021) (0)
Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels (2015) (0)
Investigations on Half Cells for Heterojunction Modules (2016) (0)
Human circulating antiviral albumin fragment (ALB-408) and its use (2007) (0)
A trip down memory lane with Retrovirology (2019) (0)
Generation and characterization of SIVagmSab infectious molecular clone and its “ HIV-1 like ” derivative (2011) (0)
Enhanced yellow fluorescent protein Æ FRET : Fluorescence resonance energy transfer Æ EDTA : Ethylenediaminetetraacetic acid Æ DMEM : Dulbecco ’ s modified Eagle ’ s medium Æ EF : Evanescent field (2006) (0)
Microglial reaction to spinal cord injury and axonal degeneration. An in vivo laser scanning microscopy study in mice. (2007) (0)
Endogenous Peptide Inhibitors of HIV Entry. (2022) (0)
Neuroprotection and gliosis attenuation by intravenous application of human mesenchymal stem cells (hMSC) following ventral root crush in mice (2021) (0)
Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis (2014) (0)
Biographical Feature: Remembering Bernhard Fleckenstein, a Generous Mentor. (2021) (0)
Serum neutralizing capacity and T-cell response against the omicron BA.1 variant in seropositive children and their parents one year after SARS-CoV-2 infection (2023) (0)
Role of the oligodendrocyte lineage in acute CNS trauma (2016) (0)
Decision letter: Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members (2019) (0)
Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1 (2023) (0)
PP 7.6 – 00036 Single cell transcriptomics identifies PTMA as a host gene that inhibits HIV during acute infection in vivo (2022) (0)
Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity (2022) (0)
Inside Back Cover Image, Volume 95, Number 1, January 2023 (2023) (0)
Magnesium-insensitive NMDA receptor currents in mouse brain astrocytes (2005) (0)
Lentiviral Nef-mediated CD4 and CD28 downmodulation (0)
ARF1 prevents aberrant type I IFN induction by regulating STING activation and recycling (2023) (0)
Decision letter: The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types (2021) (0)
Author response: Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages (2020) (0)
Near-Native Visualization of SARS-CoV-2 Induced Membrane Remodeling and Virion Morphogenesis (2022) (0)
Erratum: In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells (Cell Stem Cell (2010) 7 (744-758)) (2011) (0)
Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity (2018) (0)
Longitudinal SARS-CoV-2 infection study in a German medical school (2021) (0)
Upstream U3Sequences inSimian Immunodeficiency VirusAre Selectively Deleted InVivointheAbsence of an Intact nefGene (1994) (0)
Researchenhancement of HIV infection is donor-dependent and correlates with the levels of SEVI (2010) (0)
Human enhancers of viral infection (sevi) and its application (2007) (0)
Norepinephrine modulates salutary microglial functions in transgenic models of Alzheimer's disease (2009) (0)
N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation (2019) (0)
P2-352: Effects of anti-Aβ oligomer treatment on synaptic density in young Tg2576 mice: A preclinical model for measuring Alzheimer's disease modification (2008) (0)
Title A molecular tweezer antagonizes seminal amyloids and HIV infection (2015) (0)
Nef interferes with development of thymic T cell precursors: differential mechanisms in HIV and SIV (2011) (0)
Fibril formation by naturally occurring prostatic acid phosphatase fragments and their effect on viral infection and transduction (2014) (0)

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What Schools Are Affiliated With Frank Kirchhoff?

Frank Kirchhoff is affiliated with the following schools:

Harvard University
Saarland University
University of Ulm
University of Würzburg

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What Schools Are Affiliated With Frank Kirchhoff?

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