Frank L. Graham
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Canadian molecular biologist
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Frank L. Grahambiology Degrees
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Biology
Frank L. Graham's Degrees
- Masters Molecular Biology McGill University
- PhD Genetics University of British Columbia
Why Is Frank L. Graham Influential?
(Suggest an Edit or Addition)According to Wikipedia, Frank L. Graham is a Canadian biologist, having been a Distinguished University Professor at McMaster University. Graham is the 1998 recipient of the Robert L. Noble Prize. Graham has performed research on gene therapy.
Frank L. Graham's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A new technique for the assay of infectivity of human adenovirus 5 DNA. (1973) (8295)
- Characteristics of a human cell line transformed by DNA from human adenovirus type 5. (1977) (4789)
- Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. (1997) (1008)
- Manipulation of adenovirus vectors. (1991) (859)
- Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells (2002) (798)
- An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. (1994) (773)
- A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. (1996) (737)
- Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity (1998) (688)
- Transformation of rat cells by DNA of human adenovirus 5. (1973) (661)
- A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5. (1988) (635)
- A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes (1994) (589)
- Methods for construction of adenovirus vectors (1995) (524)
- Packaging capacity and stability of human adenovirus type 5 vectors (1993) (476)
- Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. (1999) (420)
- An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. (1998) (388)
- Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphate. (1970) (310)
- Host-range mutants of adenovirus type 5 defective for growth in HeLa cells. (1977) (301)
- Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40. (1975) (289)
- Adenovirus-based expression vectors and recombinant vaccines. (1992) (283)
- Assay of transforming activity of tumor virus DNA. (1980) (278)
- Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts. (1998) (273)
- Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. (1995) (272)
- High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity. (1998) (267)
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. (1996) (237)
- Size and location of the transforming region in human adenovirus type 5 DNA (1974) (223)
- Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. (1996) (216)
- Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis (1998) (216)
- Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA. (1977) (213)
- Cloning and sequencing of the cellular-viral junctions from the human adenovirus type 5 transformed 293 cell line. (1997) (209)
- IL-12 gene therapy protects mice in lethal Klebsiella pneumonia. (1996) (207)
- Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression (1995) (206)
- A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging (1997) (205)
- Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction. (1999) (205)
- Human adenovirus vectors for gene transfer into mammalian cells. (1997) (198)
- The Effect of 1-β-d-Arabinofuranosylcytosine on Growth, Viability, and DNA Synthesis of Mouse L-cells (1970) (193)
- Defective transforming capacity of adenovirus type 5 host-range mutants. (1978) (188)
- Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. (1995) (187)
- Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors. (1999) (173)
- Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. (1997) (173)
- Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector. (1999) (168)
- Transformation with specific fragments of adenovirus DNAs. I. Isolation of specific fragments with transforming activity of adenovirus 2 and 5 DNA. (1977) (162)
- Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. (1997) (161)
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. (2006) (156)
- Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity (1999) (155)
- Mucosal immunity and protection after intranasal immunization with recombinant adenovirus expressing herpes simplex virus glycoprotein B. (1993) (149)
- A recombinant human adenovirus vaccine against rabies. (1990) (147)
- Identification and characterization of a novel herpes simplex virus glycoprotein, gK, involved in cell fusion (1992) (147)
- Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination. (1997) (145)
- Protein IX, a minor component of the human adenovirus capsid, is essential for the packaging of full length genomes. (1987) (143)
- Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants. (1995) (142)
- Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporter. (1993) (140)
- Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer. (1998) (136)
- [2] Techniques for human adenovirus vector construction and characterization (1995) (129)
- Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. (1997) (128)
- Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: in vitro and in vivo production of biologically active interleukin-12. (1996) (127)
- ErbB2 Is Required for Muscle Spindle and Myoblast Cell Survival (2002) (126)
- Use of human adenovirus-based vectors for antigen expression in animals. (1989) (124)
- The use of adenoviral vectors for gene therapy and gene transfer in vivo. (1995) (124)
- Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene (1986) (120)
- Therapeutic serum concentrations of human alpha‐1‐antitrypsin after adenoviral‐mediated gene transfer into mouse hepatocytes (1995) (117)
- Growth of 293 cells in suspension culture. (1987) (116)
- Identification of an immunodominant cytotoxic T-lymphocyte recognition site in glycoprotein B of herpes simplex virus by using recombinant adenovirus vectors and synthetic peptides (1991) (115)
- Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models. (1999) (113)
- An enhanced system for construction of adenoviral vectors by the two-plasmid rescue method. (2000) (109)
- Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors (1999) (108)
- Development of a FLP/frt system for generating helper-dependent adenoviral vectors. (2001) (108)
- Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung. (1994) (104)
- Transformation by human adenoviruses. (1985) (103)
- Transformation by and Oncogenicity of Human Adenoviruses (1984) (102)
- Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM‐CSF in pulmonary inflammation (1996) (99)
- Construction of first-generation adenoviral vectors. (2002) (96)
- Covalently closed circles of human adenovirus DNA are infectious. (1984) (95)
- Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes. (1993) (92)
- Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre (1996) (92)
- Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A. (2004) (91)
- Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector (2000) (90)
- Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration (1999) (90)
- DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309. (1995) (89)
- A high-efficiency Cre/loxP-based system for construction of adenoviral vectors. (1999) (89)
- Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing HSV glycoprotein B. (1989) (89)
- Intracellular localization of adenovirus type 5 tumor antigens in productively infected cells. (1983) (84)
- Infectious herpesvirus DNA. (1973) (81)
- Human adenovirus type 5 vectors expressing rabies glycoprotein. (1996) (81)
- Adenovirus vectors for human gene therapy. (2000) (80)
- Development of a bovine adenovirus type 3-based expression vector. (1995) (80)
- Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus (1996) (78)
- Adenovirus E1A under the control of heterologous promoters: wide variation in E1A expression levels has little effect on virus replication. (1990) (78)
- Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector. (1988) (77)
- Human adenovirus cloning vectors based on infectious bacterial plasmids. (1986) (74)
- Preparation of helper-dependent adenoviral vectors. (2002) (73)
- A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model. (1998) (71)
- Tumor antigens of human ad5 in transformed cells and in cells infected with transformation-defective host-range mutants (1979) (68)
- Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer. (1998) (68)
- Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function. (1993) (68)
- Large nontransplanted hepatocellular carcinoma in woodchucks: treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes. (2001) (67)
- A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer (2003) (67)
- Protective immunity to rotavirus-induced diarrhoea is passively transferred to newborn mice from naive dams vaccinated with a single dose of a recombinant adenovirus expressing rotavirus VP7sc. (1993) (64)
- Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms (1998) (63)
- Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity (1994) (63)
- Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors. (2005) (62)
- The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells. (1998) (62)
- Immune response to HIV-1 gag antigens induced by recombinant adenovirus vectors in mice and rhesus macaque monkeys. (1991) (62)
- Transduction of human bone marrow by adenoviral vector. (1994) (59)
- Mouse hepatitis virus spike and nucleocapsid proteins expressed by adenovirus vectors protect mice against a lethal infection. (1993) (59)
- Herpes simplex virus IgG Fc receptors induced using recombinant adenovirus vectors expressing glycoproteins E and I. (1990) (59)
- Tn5 mutagenesis of the transforming genes of human adenovirus type 5. (1982) (59)
- Adenoviruses as expression vectors and recombinant vaccines. (1990) (58)
- Sedimentation analysis of DNA from irradiated and unirradiated L-cells. (1972) (56)
- Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1-type pulmonary granulomas. (1997) (54)
- Covalently closed circles of adenovirus 5 DNA (1983) (53)
- Transient gene transfer of IL-12 regulates chemokine expression and disease severity in experimental arthritis. (1998) (51)
- Construction and Propagation of Human Adenovirus Vectors (2006) (51)
- Relation of Herpes simplex viruses to human malignancies. (1977) (51)
- Cytotoxic T lymphocytes specific for herpes simplex virus (HSV) studied using adenovirus vectors expressing HSV glycoproteins. (1990) (50)
- Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung. (1996) (50)
- A single intramuscular injection with an adenovirus-expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatment with an IL-4-expressing vector increases disease susceptibility in B10.D2 mice. (1999) (50)
- Immunoprecipitation of protein kinase activity from adenovirus 5-infected cells using antiserum directed against tumour antigens (1979) (50)
- Inhibition of cell-proliferation by an adenovirus vector expressing the human wild type-p53 protein. (1993) (49)
- Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice (2004) (49)
- Tumour therapy in mice using adenovirus vectors expressing human TNFa. (1998) (49)
- Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes (1995) (48)
- Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells. (1986) (48)
- Anomalous sedimentation of high molecular weight denatured mammalian DNA. (1971) (45)
- Characterization of human adenovirus type 5 early region 1A polypeptides using antitumor sera and an antiserum specific for the carboxy terminus. (1983) (45)
- Expression of the glycoprotein of vesicular stomatitis virus by infectious adenovirus vectors. (1989) (44)
- Cre Levels Limit Packaging Signal Excision Efficiency in the Cre/loxP Helper-Dependent Adenoviral Vector System (2002) (44)
- Tumorigenicity of adenovirus-transformed rodent cells is influenced by at least two regions of adenovirus type 12 early region 1A (1994) (44)
- Herpes simplex virus (HSV) glycoproteins B and K inhibit cell fusion induced by HSV syncytial mutants. (1993) (44)
- Expression of a mutation causing hypertrophic cardiomyopathy disrupts sarcomere assembly in adult feline cardiac myocytes. (1995) (43)
- Adenovirus vectors for high-efficiency gene transfer into mammalian cells (2000) (43)
- Mapping of a 14,000-dalton antigen to early region 4 of the human adenovirus 5 genome (1983) (43)
- Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein (1995) (42)
- Gene targeting in mouse embryonic stem cells with an adenoviral vector (1995) (39)
- Superior tissue-specific expression from tyrosinase and prostate-specific antigen promoters/enhancers in helper-dependent compared with first-generation adenoviral vectors. (2002) (39)
- Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors. (1993) (39)
- Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular targeting using adenovirus‐mediated expression (2004) (39)
- Development and use of a 293 cell line expressing lac repressor for the rescue of recombinant adenoviruses expressing high levels of rabies virus glycoprotein. (1999) (38)
- Adenovirus-mediated gene transfer in the transplant setting. I. Conditions for expression of transferred genes in cold-preserved hepatocytes. (1994) (38)
- Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance. (1998) (38)
- Tumorigenicity and viral gene expression in rat cells transformed by Ad 12 virions or by the EcoRI c fragment of Ad 12 DNA. (1979) (37)
- 4 Structure and Genetic Organization of Adenovirus Vectors (1999) (36)
- Adenovirus vector expressing mouse oncostatin M induces acute-phase proteins and TIMP-1 expression in vivo in mice. (1999) (35)
- Infectious circular DNA of human adenovirus type 5: regeneration of viral DNA termini from molecules lacking terminal sequences. (1989) (35)
- Heterogeneity of the immune response to adenovirus‐mediated factor VIII gene therapy in different inbred hemophilic mouse strains (2004) (35)
- Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma (2001) (34)
- Attenuation of the glucocorticoid response during Ad5IL-12 adenovirus vector treatment enhances natural killer cell-mediated killing of MHC class I-negative LNCaP prostate tumors. (2007) (33)
- Integration and expression of viral DNA in cells transformed by host range mutants of adenovirus type 5 (1982) (33)
- An adenoviral vector expressing interleukin-4 modulates tumorigenicity and induces regression in a murine breast-cancer model. (1995) (33)
- Yeast recombinase FLP functions effectively in human cells for construction of adenovirus vectors. (2000) (32)
- Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters (1981) (32)
- The E1 sequence of bovine adenovirus type 3 and complementation of human adenovirus type 5 E1A function in bovine cells. (1994) (31)
- Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-gamma-lactone oxidase. (2004) (30)
- Transformation of rodent cells by DNA extracted from transformation-defective adenovirus mutants (1983) (30)
- Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes. (1996) (30)
- Identification of adenovirus E1A regions which affect MHC class I expression and susceptibility to cytotoxic T lymphocytes. (1995) (30)
- Foreign gene expression by human adenovirus type 5-based vectors studied using firefly luciferase and bacterial beta-galactosidase genes as reporters. (1995) (29)
- A convenient plasmid system for construction of helper‐dependent adenoviral vectors and its application for analysis of the breast‐cancer‐specific mammaglobin promoter (2006) (28)
- Biological activity of tumor virus DNA. (1977) (28)
- Complementation of adenovirus type 5 host range mutants by adenovirus type 12 in coinfected HeLa and BHK-21 cells (1981) (28)
- Recombinant truncated dystrophin minigenes: construction, expression, and adenoviral delivery. (1995) (27)
- Establishment and characterization of hamster cell lines transformed by restriction endonuclease fragments of adenovirus 5 (1984) (27)
- Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4 or -101 (2003) (27)
- High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase (1995) (27)
- A phase I study of adenovirus mediated gene transfer of interleukin 2 cDNA into metastatic breast cancer or melanoma. (1997) (27)
- The kinetics of synthesis of early viral proteins in KB cells infected with wild-type and transformation-defective host-range mutants of human adenovirus type 5. (1984) (26)
- The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kappa B to the MHC class I enhancer in transformed cells. (1996) (26)
- Anti-adenovirus type 5 cytotoxic T lymphocytes: immunodominant epitopes are encoded by the E1A gene (1991) (26)
- Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice (2005) (26)
- Investigation of promoter function in human and animal cells infected with human recombinant adenovirus expressing rotavirus antigen VP7sc. (1995) (25)
- Synthesis and processing of the haemagglutinin-esterase glycoprotein of bovine coronavirus encoded in the E3 region of adenovirus. (1992) (24)
- Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells. (1978) (23)
- Sequence analysis of bovine adenovirus type 3 early region 3 and fibre protein genes. (1992) (23)
- Transformation by human adenoviruses (1984) (23)
- Isolation and characterization of insertion mutants in E1A of adenovirus type 5. (1991) (23)
- Characterization of an adenovirus type 5 mutant carrying embedded inverted terminal repeats. (1986) (22)
- Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung. (1996) (21)
- Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range (1992) (21)
- Adenovirus‐Vector‐Mediated Cytokine Gene Transfer to Lung Tissue a (1996) (19)
- A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity (1999) (18)
- Intramarrow cytokine gene transfer by adenoviral vectors in dogs. (1997) (18)
- Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors. (1997) (18)
- Nonrandom insertion of Tn5 into cloned human adenovirus DNA. (1985) (17)
- Recombinant adenovirus vectors expressing interleukin‐5 and ‐6 specifically enhance mucosal immunoglobulin A responses in the lung (2000) (17)
- Adenoviruses with nonidentical terminal sequences are viable (1989) (17)
- Life-long systemic protection in mice vaccinated with L. major and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes. (2004) (15)
- Transcription units of E1a, E1b and pIX regions of bovine adenovirus type 3. (1999) (15)
- Adenovirus vectors for gene expression and gene therapy (1996) (14)
- Transforming proteins of human adenovirus 5: studies with infected and transformed cells. (1980) (14)
- Transient gene transfer and expression in the lung. (1997) (14)
- Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene. (1996) (14)
- HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice (2012) (14)
- Enhanced interleukin-2 gene transfer immunotherapy of breast cancer by coexpression of B7-1 and B7-2. (1998) (13)
- Function and immunogenicity of human parainfluenza virus 3 glycoproteins expressed by recombinant adenoviruses. (1992) (12)
- Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice (2010) (12)
- Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector. (1987) (12)
- In vivo adenoviral-mediated gene transfer of interleukin-2 in cutaneous plasmacytoma. (1998) (12)
- Mucosal immunization with a recombinant adenovirus vector induces local and systemic immunity and protection from herpes simplex virus. (1995) (11)
- Testing NF-kappa B1-p50 antibody specificity using knockout mice. (1996) (11)
- The human SCGB2A2 (mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells. (2004) (11)
- Adenovirus Vectors for Cytokine Gene Expression (1995) (11)
- Insertional mutagenesis using a synthetic lac operator. (1990) (10)
- Adenoviral-mediated gene transfer of lymphotactin to the lungs of mice and rats results in infiltration and direct accumulation of CD4+, CD8+, and NK cells. (2002) (9)
- Sequence analysis of bovine adenovirus type 3 early region 3 and fibre protein genes. (1992) (9)
- Autologous lymphocyte responses to adenovirus-B7-1-transduced human cancer cells (1999) (8)
- Protein kinase and ATP-binding activity associated with the 72-kdalton single-stranded DNA-binding protein from early region 2A of human adenovirus type 5. (1985) (8)
- The adenovirus e1a-associated p300 protein is differentially phosphorylated in ad12 e1a-compared to ad5 e1a-transformed rat-cells. (1994) (7)
- B7-1 gene transfer into human cancer cells by infection with an adenovirus-B7 (Ad-B7) expression vector (1996) (7)
- The effect of-beta-D-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells. (1970) (7)
- Characterization of human TK- cell lines transformed to a TK+ phenotype by herpes simplex virus type 2 DNA. (1979) (7)
- Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection. (1998) (6)
- The cleavage site of restriction endonuclease MnlI. (1991) (6)
- Adenoviral Vector Construction I (2002) (5)
- Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor (1997) (4)
- Transduction of the CHOaprt gene into mouse L cells using an adeno-5/APRT recombinant virus (1991) (4)
- The facilitative role of epithelial barrier disruption in successful gene transfer to the colon (1998) (2)
- The effect of E1 mutations on biochemical transformation by an adenovirus carrying the herpes simplex virus thymidine kinase gene in region E3. (1989) (2)
- IL-4-Expressing Vector Increases Disease Infection, While Treatment with an BALB/c Mice Against Leishmania major Adenovirus- Expressing IL-12 Protects A Single Intramuscular Injection with an (2013) (2)
- Tissue directed recruitment of mononuclear cells to the lung using a recombinant adenovirus expressing murine RANTES (1994) (2)
- DNA-mediated transfer of herpes simplex virus TK gene to human TK- cells: properties of the transformed lines. (1978) (2)
- Studies on transformation of mammalian cells by human adenovirus type 5 (Ad5) and Ad5 DNA. (1983) (2)
- Discussion Mammalian Cell Killing by Inhibitors of DNA Synthesis (1969) (2)
- The use of three hemophilia A mouse models to illustrate strain-specific differences in immune responses to FVIII protein replacement via protein infusion or adenoviral gene therapy (2003) (1)
- Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation. (1997) (1)
- Arabinofuranosylcytosine into DNA and on Inhibition of DNA Polymerase by 1-0-o-Arabinofuranosylcytosine 5'-Triphosphate* (1970) (1)
- Induction of an immune response to transmissible gastroenteritis coronavirus using vectors with enteric tropism. (1993) (1)
- Experimental Arthritis Chemokine Expression and Disease Severity in Transient Gene Transfer of IL-12 Regulates (1998) (0)
- Collagen-Induced Arthritis Prevents of IL-4 in the Knee Joint of Mice with Adenoviral Vector-Mediated Overexpression and (1999) (0)
- The expression of rhabdovirus antigens in human adenovirus vectors (1988) (0)
- TUMOR REGRESSION BY AD VECTORS ENCODING IL-2 AND p 53 709 Recombinant adenoviruses (2008) (0)
- Development of a Second-Generation, Helper-Dependent Adenovirus-Based Model of Glaucoma (2012) (0)
- Adenovirus Type 5 EBB Protein Regulates Transforming Activity (2003) (0)
- Systeme evolue destine a la creation de vecteurs d'adenovirus (2000) (0)
- Rapid Publication Patient Selection May Affect Gene Therapy Success Dominant Negative Effects Observed for Ornithine Transcarbamylase in Mouse and Human Hepatocytes (1996) (0)
- growth factor-induced mitogenesis (1986) (0)
- Matrix Modulation Using Fibrogenic Gene Transfer (1997) (0)
- Helper-Independent Live Recombinant Adenovirus Vector Expressing the Hemagglutinin-Esterase Membrane Glycoprotein (1992) (0)
- Susceptibility in B 10 . D 2 Mice IL-4-Expressing Vector Increases Disease Infection , While Treatment with an Leishmania major BALB / c Mice Against Adenovirus-Expressing IL-12 Protects A Single Intramuscular Injection with an (1998) (0)
- ErratumInsertional mutagenesis using a synthetic lac operator (1990) (0)
- Adenoviral gene therapy for duchenne muscular dystrophy (1996) (0)
- Anefficient andflexible system forconstruction ofadenovirus vectors withinsertions ordeletions inearly regions 1and3 (1994) (0)
- 694. Breast Cancer Specificity, Anti-Tumor Activity, and Reduced Toxicity of an Adenoviral Vector Encoding Interleukin-2 under Control of the Human Mammaglobin Promoter (2005) (0)
- EVASION OF THE HUMAN CELLULAR IMMUNE RESPONSE BY HERPES SIMPLEX VIRUS (2010) (0)
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