Frank l. Van De Veerdonk
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Frank l. Van De Veerdonkbiology Degrees
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Biology
Why Is Frank l. Van De Veerdonk Influential?
(Suggest an Edit or Addition)Frank l. Van De Veerdonk's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity (2014) (1314)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 (2021) (1105)
- A minimal common outcome measure set for COVID-19 clinical research (2020) (939)
- Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. (2009) (765)
- Inflammasome activation and IL-1β and IL-18 processing during infection. (2011) (604)
- Inflammasome is a central player in the induction of obesity and insulin resistance (2011) (602)
- STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. (2011) (584)
- Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. (2020) (583)
- Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study. (2018) (558)
- Presence of Genetic Variants Among Young Men With Severe COVID-19. (2020) (530)
- Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 (2021) (508)
- Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 (2021) (485)
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. (2016) (483)
- IL-1β Processing in Host Defense: Beyond the Inflammasomes (2010) (471)
- A guiding map for inflammation (2017) (402)
- Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis (2016) (395)
- Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype. (2016) (394)
- Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection (2020) (338)
- The macrophage mannose receptor induces IL-17 in response to Candida albicans. (2009) (330)
- IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist (2012) (291)
- Inflammasome-independent regulation of IL-1-family cytokines. (2015) (281)
- Modulation of inflammation by autophagy: Consequences for human disease (2015) (273)
- COVID-19 Associated Pulmonary Aspergillosis (CAPA)—From Immunology to Treatment (2020) (263)
- IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans (2014) (262)
- Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. (2010) (258)
- Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion (2020) (248)
- The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency. (2016) (233)
- Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease (2010) (223)
- IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections (2016) (218)
- Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome (2020) (211)
- Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis (2020) (210)
- IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis (2016) (190)
- Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series (2014) (186)
- The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans (2011) (185)
- Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2 (2011) (184)
- Inflammasome-Independent Modulation of Cytokine Response by Autophagy in Human Cells (2011) (181)
- The anti-CD20 antibody rituximab reduces the Th17 cell response. (2011) (172)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (168)
- Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity. (2016) (166)
- Host-microbe interactions: innate pattern recognition of fungal pathogens. (2008) (157)
- Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer (2014) (149)
- New Insights in the Immunobiology of IL-1 Family Members (2013) (148)
- A guide to immunotherapy for COVID-19 (2022) (146)
- Influenza-Associated Aspergillosis in Critically Ill Patients. (2017) (146)
- Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects. (2014) (142)
- Diagnosing COVID-19-associated pulmonary aspergillosis (2020) (142)
- IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis (2014) (142)
- Phenotype, penetrance, and treatment of 133 cytotoxic T‐lymphocyte antigen 4–insufficient subjects (2018) (141)
- Biology of IL-36 cytokines and their role in disease. (2013) (138)
- The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis (2011) (136)
- Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects (2016) (131)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report (2021) (131)
- Th17 responses and host defense against microorganisms: an overview. (2009) (127)
- Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2021) (123)
- Corticosteroids Block Autophagy Protein Recruitment in Aspergillus fumigatus Phagosomes via Targeting Dectin-1/Syk Kinase Signaling (2013) (120)
- Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients (2020) (119)
- Anti‐Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity (2010) (119)
- Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus (2018) (112)
- A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist (2014) (108)
- STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis (2011) (108)
- In-host adaptation and acquired triazole resistance in Aspergillus fumigatus: a dilemma for clinical management. (2016) (107)
- Role of TLR1 and TLR6 in the host defense against disseminated candidiasis. (2008) (106)
- Genetic susceptibility to Candida infections (2013) (106)
- Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. (2018) (102)
- Confronting and mitigating the risk of COVID-19 associated pulmonary aspergillosis (2020) (99)
- Degradation and debittering of a tryptic digest from beta-casein by aminopeptidase N from Lactococcus lactis subsp. cremoris Wg2 (1993) (97)
- Inflammasome-independent Role of Apoptosis-associated Speck-like Protein Containing a CARD (ASC) in T Cell Priming Is Critical for Collagen-induced Arthritis* (2010) (96)
- Candida albicans Dampens Host Defense by Downregulating IL-17 Production (2010) (94)
- The IL‐36 receptor pathway regulates Aspergillus fumigatus‐induced Th1 and Th17 responses (2013) (93)
- Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway (2017) (93)
- Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study (2020) (87)
- Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study (2020) (87)
- Pathogenesis of invasive candidiasis (2010) (87)
- Transcriptional and inflammasome‐mediated pathways for the induction of IL‐1β production by Mycobacterium tuberculosis (2009) (86)
- Immunotherapeutic approaches to treatment of fungal diseases. (2017) (85)
- Influenza virus and factors that are associated with ICU admission, pulmonary co-infections and ICU mortality (2018) (85)
- Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis (2021) (83)
- Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia (2014) (80)
- Skin Microbiome Imbalance in Patients with STAT1/STAT3 Defects Impairs Innate Host Defense Responses (2013) (78)
- Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. (2009) (77)
- The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2. (2010) (76)
- T-cell Subsets and Antifungal Host Defenses (2010) (75)
- Biology of IL‐38 and its role in disease (2018) (73)
- Increased Plasma Heparanase Activity in COVID-19 Patients (2020) (72)
- Blocking IL-1 to prevent respiratory failure in COVID-19 (2020) (72)
- Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra. (2015) (70)
- Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes (2020) (69)
- Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis (2017) (67)
- Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses (2012) (67)
- Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study (2020) (66)
- Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia (2011) (62)
- The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases (2014) (60)
- Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra (2015) (60)
- The classical CD14++CD16− monocytes, but not the patrolling CD14+CD16+ monocytes, promote Th17 responses to Candida albicans (2011) (59)
- Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway (2016) (58)
- Severe Candida spp. infections: new insights into natural immunity. (2010) (54)
- Redundant role of TLR9 for anti-Candida host defense. (2008) (54)
- The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus‐related lung disease (2014) (53)
- Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2022) (52)
- IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation. (2015) (52)
- Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19. (2021) (51)
- Compartmentalized Cytokine Responses in Hidradenitis Suppurativa (2015) (50)
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity (2020) (49)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19 (2020) (48)
- Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection (2020) (48)
- Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses (2015) (47)
- Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19 (2021) (47)
- Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC (2016) (46)
- Multinational Observational Cohort Study of COVID-19–Associated Pulmonary Aspergillosis (2021) (46)
- Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies (2019) (46)
- Novel strategies for the prevention and treatment of Candida infections: the potential of immunotherapy. (2010) (46)
- Receptor Recognition of and Immune Intracellular Pathways for Veillonella parvula Lipopolysaccharide (2009) (45)
- Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris (2020) (45)
- Adult-onset autoinflammation caused by somatic mutations in UBA1: A Dutch case series of VEXAS patients. (2021) (45)
- Borrelia species induce inflammasome activation and IL‐17 production through a caspase‐1‐dependent mechanism (2011) (44)
- Combination of biomarkers for the discrimination between bacterial and viral lower respiratory tract infections. (2012) (44)
- Risks of Ruxolitinib in STAT1 Gain-of-Function-Associated Severe Fungal Disease (2017) (43)
- Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 (2020) (43)
- COVID-19-associated Aspergillus tracheobronchitis: the interplay between viral tropism, host defence, and fungal invasion (2021) (42)
- Association of esophageal candidiasis and squamous cell carcinoma. (2012) (42)
- Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease. (2011) (41)
- The Multifaceted Role of T-Helper Responses in Host Defense against Aspergillus fumigatus (2017) (41)
- Recognition of DHN-melanin by MelLec, is required for protective immunity to Aspergillus (2018) (41)
- IL-18 serum concentration is markedly elevated in acute EBV infection and can serve as a marker for disease severity. (2012) (40)
- An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. (2015) (39)
- Aspergillus Test Profiles and Mortality in Critically Ill COVID-19 Patients (2021) (39)
- Diversity: a hallmark of monocyte society. (2010) (39)
- The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis (2016) (38)
- The role of NLRs and TLRs in the activation of the inflammasome (2008) (38)
- Aspergillus fumigatus–Induced IL-22 Is Not Restricted to a Specific Th Cell Subset and Is Dependent on Complement Receptor 3 (2013) (37)
- Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients (2021) (37)
- Understanding COVID-19-associated coagulopathy (2022) (37)
- Deficient autophagy unravels the ROS paradox in chronic granulomatous disease (2014) (36)
- A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis (2019) (36)
- Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout (2020) (36)
- Defective trained immunity in patients with STAT‐1‐dependent chronic mucocutaneaous candidiasis (2015) (35)
- Milder clinical hyperimmunoglobulin E syndrome phenotype is associated with partial interleukin‐17 deficiency (2010) (35)
- Genetic deficiency of NOD2 confers resistance to invasive aspergillosis (2018) (35)
- Posaconazole for prevention of invasive pulmonary aspergillosis in critically ill influenza patients (POSA-FLU): a randomised, open-label, proof-of-concept trial (2021) (34)
- Posaconazole for prevention of invasive pulmonary aspergillosis in critically ill influenza patients (POSA-FLU): a randomised, open-label, proof-of-concept trial (2021) (34)
- The role of NLRs and TLRs in the activation of the inflammasome. (2008) (32)
- Progressive multifocal leukoencephalopathy in an immunocompetent patient (2016) (31)
- Pattern recognition receptors and their role in invasive aspergillosis (2012) (30)
- Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor (2016) (30)
- Adjunctive immunotherapy with recombinant cytokines for the treatment of disseminated candidiasis. (2012) (29)
- COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients (2020) (29)
- Treatment options for chronic mucocutaneous candidiasis. (2016) (29)
- A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients (2021) (28)
- Moderate correlation between systemic IL‐6 responses and CRP with trough concentrations of voriconazole (2018) (28)
- Basic Genetics and Immunology of Candida Infections. (2016) (27)
- Differential susceptibility to lethal endotoxaemia in mice deficient in IL‐1α, IL‐1β or IL‐1 receptor type I (2010) (27)
- Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3 (2012) (26)
- Autophagy Modulates Borrelia burgdorferi-induced Production of Interleukin-1β (IL-1β)* (2013) (25)
- Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37 (2015) (25)
- Immunotherapy: a potential adjunctive treatment for fungal infection (2014) (24)
- Interferon gamma immunotherapy in five critically ill COVID-19 patients with impaired cellular immunity: A case series (2021) (24)
- Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources (2021) (23)
- Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory (2016) (23)
- Invasive pulmonary aspergillosis associated with viral pneumonitis. (2021) (22)
- Anakinra for the inflammatory complications of chronic granulomatous disease. (2011) (22)
- Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity (2022) (22)
- Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin (2020) (21)
- Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects (2019) (21)
- Host Genetic Signatures of Susceptibility to Fungal Disease. (2018) (21)
- Th17 cytokine deficiency in patients with Aspergillus skull base osteomyelitis (2015) (21)
- A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans. (2019) (20)
- Increased Plasma Heparanase Activity in COVID-19 Patients (2020) (20)
- An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility (2017) (20)
- Low interleukin-17A production in response to fungal pathogens in patients with chronic granulomatous disease. (2012) (20)
- Influenza Coinfection: Be(a)ware of Invasive Aspergillosis (2019) (20)
- Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis. (2015) (18)
- A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection (2020) (18)
- Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans (2019) (18)
- Efficacy of Bacillus Calmette-Guérin vaccination against respiratory tract infections in the elderly during the Covid-19 pandemic. (2022) (16)
- The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression (2017) (16)
- Detection of Invasive Aspergillosis in Critically Ill Patients with Influenza: the Role of Plasma Galactomannan. (2019) (16)
- Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure. (2010) (16)
- Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis (2012) (15)
- The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses (2021) (15)
- Flucloxacillin Results in Suboptimal Plasma Voriconazole Concentrations (2017) (15)
- Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis. (2021) (15)
- Deficient Candida-specific T-helper 17 response during sepsis. (2012) (15)
- IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling (2021) (15)
- Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
- Deficient interleukin-17 production in response to Mycobacterium abscessus in cystic fibrosis (2016) (14)
- Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis (2021) (14)
- MST1R mutation as a genetic cause of Lady Windermere syndrome (2017) (14)
- Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity (2021) (14)
- Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics (2017) (14)
- Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study (2022) (14)
- Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease. (2020) (14)
- The association of TSH and thyroid hormones with lymphopenia in bacterial sepsis and COVID-19 (2021) (14)
- STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE. (2019) (14)
- Lysine methyltransferase G9a is an important modulator of trained immunity (2021) (13)
- Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent. (2015) (13)
- Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis (2017) (13)
- Comparison between myocardial function assessed by echocardiography during hospitalization for COVID-19 and at 4 months follow-up (2021) (12)
- Autoimmune Regulator Deficiency Results in a Decrease in STAT1 Levels in Human Monocytes (2017) (12)
- Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo (2017) (12)
- 967. Inhibition of Host Neuraminidase Increases Susceptibility to Invasive Pulmonary Aspergillosis (2018) (11)
- Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model (2021) (11)
- Defects of pattern recognition: primary immunodeficiencies of the innate immune system. (2011) (11)
- The challenge of managing COVID-19 associated pulmonary aspergillosis (2020) (11)
- When the Fight against Fungi Goes Wrong (2016) (11)
- Antifungal immune responses: emerging host–pathogen interactions and translational implications (2018) (11)
- Does Pulmonary Aspergillosis Complicate Coronavirus Disease 2019? (2020) (10)
- Efficacy of BCG Vaccination Against Respiratory Tract Infections in Older Adults During the Coronavirus Disease 2019 Pandemic (2022) (9)
- An Omics Perspective on Candida Infections: Toward Next-Generation Diagnosis and Therapy (2016) (9)
- Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways (2020) (8)
- Natural resistance against infections: focus on COVID-19 (2021) (8)
- Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses. (2017) (8)
- Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient (2018) (8)
- Immune Parameters for Diagnosis and Treatment Monitoring in Invasive Mold Infection (2019) (8)
- The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production. (2013) (7)
- Primary immunodeficiencies in cytosolic pattern‐recognition receptor pathways: Toward host‐directed treatment strategies (2020) (7)
- Invasive Aspergillus Tracheobronchitis Emerging as a Highly Lethal Complication of Severe Influenza (2020) (7)
- Implementation of Early Next-Generation Sequencing for Inborn Errors of Immunity: A Prospective Observational Cohort Study of Diagnostic Yield and Clinical Implications in Dutch Genome Diagnostic Centers (2021) (6)
- Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease (2020) (6)
- Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses (2020) (6)
- A Human Dectin-2 Deficiency Associated With Invasive Aspergillosis (2021) (6)
- Antifungal innate immunity: recognition and inflammatory networks (2014) (6)
- Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19 (2021) (6)
- Stimulating severe COVID-19: the potential role of GM-CSF antagonism (2021) (5)
- An Exaggerated Monocyte-Derived Cytokine Response to Candida Hyphae in Patients With Recurrent Vulvovaginal Candidiasis (2020) (5)
- Immune defects in patients with pulmonary Mycobacterium abscessus disease without cystic fibrosis (2020) (5)
- Platelets Modulate IFN-γ Production against Candida albicans in Peripheral Blood Mononuclear Cells via Prostaglandins (2019) (5)
- Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2021) (5)
- A Multidisciplinary Approach to Fungal Infections: One-Year Experiences of a Center of Expertise in Mycology (2020) (5)
- Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis (2022) (5)
- Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. (2021) (4)
- Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis (2021) (4)
- OP0170 Human il-38 reduces joint inflammation in a mouse model of gouty arthritis (2018) (4)
- Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy. (2016) (4)
- Cytokine Production Assays Reveal Discriminatory Immune Defects in Adults with Recurrent Infections and Noninfectious Inflammation (2014) (4)
- STAT1 gain-of-function compromises skin host defense in the context of IFN-γ signaling. (2019) (4)
- Managing secondary fungal infections in severe COVID-19: how to move forward? (2021) (4)
- Liposomal amphotericin B—the future (2022) (3)
- Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19 (2022) (3)
- Data of common and species-specific transcriptional host responses to pathogenic fungi (2021) (3)
- Adipocytokine plasma concentrations reflect influence of inflammation but not body mass index (BMI) on clinical outcomes of COVID‐19 patients: A prospective observational study from the Netherlands (2022) (3)
- Personalized medicine in influenza: a bridge too far or the near future? (2017) (3)
- Author response: Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome (2020) (3)
- [Medication and comedication in COVID-19 patients]. (2020) (3)
- Rare variants increase the risk of severe COVID-19 (2021) (3)
- SARS-CoV-2-Induced Multisystem Inflammatory Syndrome in a Young Adult: Case Report (2021) (3)
- Challenges and Opportunities in Understanding Genetics of Fungal Diseases: Towards a Functional Genomics Approach (2021) (2)
- P105 Identification of rare coding variants in IL-1-related pathways in patients with adult-onset still’s disease (2018) (2)
- The potential role for topical imiquimod in the treatment of chronic mucocutaneous candidiasis caused by gain‐of‐function mutation in STAT1: A case‐report (2021) (2)
- Patient with fever and diarrhea. (2006) (2)
- The Renin-Angiotensin System in Acute Lung Injury. (2022) (2)
- The genetic risk for COVID-19 severity is associated with defective innate immune responses (2020) (2)
- Author Correction: A guiding map for inflammation (2020) (2)
- Chloroquine for treatment of COVID-19 - a pig in a poke? (2020) (1)
- Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial. (2023) (1)
- The effects of signal transducer and activator of transcription three mutations on human platelets (2018) (1)
- Genetic determinants of fungi-induced ROS production are associated with the risk of invasive pulmonary aspergillosis (2022) (1)
- Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity (2023) (1)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (1)
- Human variation in population-wide gene expression data predicts gene perturbation phenotype (2022) (1)
- SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients (2022) (1)
- Misleading one‐stage coagulation factor assay during rFVIIa treatment in lupus patient (2009) (1)
- Autophagy is redundant for the host defense against systemic Candida albicans infections (2013) (1)
- Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: A retrospective cohort study (2022) (1)
- The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections (2015) (1)
- Immunogenicity of the mRNA-1273 COVID-19 Vaccine in Patients With Inborn Errors of Immunity (2022) (1)
- Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients – study rationale and protocol of the CORONIS study: A multicentre prospective cohort study (2022) (1)
- The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses (2022) (1)
- Immunological effects of anti-IL-17/12/23 therapy in patients with psoriasis complicated by Candida infections. (2022) (1)
- Case 39-2014: A girl with Crohn's disease and pulmonary nodules. (2015) (1)
- The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases (2014) (1)
- Chloroquine for treatment of COVID-19 results in subtherapeutic exposure and prolonged QTc intervals (2021) (1)
- Mimicking Behçet’s disease: GM‐CSF gain of function mutation in a family suffering from a Behçet’s disease‐like disorder marked by extreme pathergy (2020) (1)
- A functional genomics approach to understand host genetic regulation ofCOVID-19 severity (2020) (1)
- Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies (2019) (1)
- Activation of cytokine responses by Candida africana. (2022) (1)
- Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial (2023) (1)
- Itraconazole or Amphotericin B for Talaromycosis. (2017) (1)
- Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses (2021) (1)
- Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12 (2022) (1)
- No indications for overt innate immune suppression in critically ill COVID-19 patients (2020) (1)
- Proinflammatory Cytokine Responses Neutrophil-Mediated Inhibition of (0)
- Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus (2022) (0)
- Antifungal immune responses: emerging host–pathogen interactions and translational implications (2018) (0)
- Decision letter: A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm (2020) (0)
- Decision letter: Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis (2020) (0)
- Decision letter: Identification of drugs associated with reduced severity of COVID-19 – a case-control study in a large population (2021) (0)
- Genome-Wide Association Study Reveals CLEC7A and PROM1 as Potential Regulators of Paracoccidioides brasiliensis-Induction of Cytokine Production in Peripheral Blood Mononuclear Cells (2023) (0)
- Editor's evaluation: Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells (2021) (0)
- A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis (2023) (0)
- Could treatment with immunomodulatory agents targeting IL-1, IL-6, or JAK signalling improve outcomes in patients with severe influenza pneumonia? A systematic and narrative review (2022) (0)
- Decision letter: Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement (2020) (0)
- OP0285 Identification of rare coding variants in il-1-related pathways in patients with adult-onset still’s disease (2018) (0)
- The Role of Interleukin-1 Family Members in the Host Defence Against Aspergillus fumigatus (2014) (0)
- Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19 (2022) (0)
- S3.3d Influenza versus COVID-19-associated pulmonary aspergillosis: Profiling lower respiratory tract epithelial and myeloid innate immunity in patient samples (2022) (0)
- Genetic deficiency of NOD2 confers resistance to invasive aspergillosis (2018) (0)
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity (2020) (0)
- Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients (2022) (0)
- Circulating galectin-3 in infections and non-infectious inflammatory diseases (2013) (0)
- Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC (2016) (0)
- Decision letter: Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection (2020) (0)
- Editorial overview: Emerging topics in host-fungus interactions. (2020) (0)
- Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics (2017) (0)
- Incidence, risk factors and pre-emptive screening for COVID-19 associated pulmonary aspergillosis in an era of immunomodulant therapy (2023) (0)
- A limited role of cytokine storm and fibrogenesis in COVID-19 related liver injury. (2021) (0)
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