Franziska Michor
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Austrian biomathematician
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Franziska Michormathematics Degrees
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Mathematics
Franziska Michor's Degrees
- PhD Mathematics University of Vienna
- Masters Mathematics University of Vienna
Why Is Franziska Michor Influential?
(Suggest an Edit or Addition)According to Wikipedia, Franziska Michor is an Austrian-American computational biologist who is a Professor in the Department of Data Science at the Dana–Farber Cancer Institute. She serves as Director of the Physical Sciences-Oncology Center and the Center for Cancer Evolution.
Franziska Michor's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Clonal Evolution in Breast Cancer Revealed by Single Nucleus Genome Sequencing (2014) (902)
- Dynamics of chronic myeloid leukaemia (2005) (818)
- The mathematics of cancer: integrating quantitative models (2015) (511)
- Optimization of Dosing for EGFR-Mutant Non–Small Cell Lung Cancer with Evolutionary Cancer Modeling (2011) (503)
- Dynamics of cancer progression (2004) (437)
- Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease. (2013) (424)
- Punctuated Copy Number Evolution and Clonal Stasis in Triple-Negative Breast Cancer (2016) (375)
- Studying clonal dynamics in response to cancer therapy using high-complexity barcoding (2015) (375)
- Computational Modeling of Pancreatic Cancer Reveals Kinetics of Metastasis Suggesting Optimum Treatment Strategies (2012) (374)
- Polyploidy can drive rapid adaptation in yeast (2015) (342)
- Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. (2010) (324)
- Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. (2014) (322)
- Synergy and discounting of cooperation in social dilemmas. (2006) (293)
- Non-cell autonomous tumor-growth driving supports sub-clonal heterogeneity (2014) (282)
- Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq (2018) (274)
- Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma. (2017) (270)
- Successful Therapy Must Eradicate Cancer Stem Cells (2006) (250)
- Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. (2014) (243)
- Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response (2004) (243)
- Mathematical Modeling of PDGF-Driven Glioblastoma Reveals Optimized Radiation Dosing Schedules (2014) (241)
- Stochastic Tunnels in Evolutionary Dynamics (2004) (237)
- Evolution of Resistance During Clonal Expansion (2006) (230)
- JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response. (2015) (224)
- A novel tumor suppressor function for the Notch pathway in myeloid leukemia (2011) (220)
- DNA secondary structures and epigenetic determinants of cancer genome evolution (2010) (218)
- Evolution of acquired resistance to anti-cancer therapy. (2014) (207)
- The linear process of somatic evolution (2003) (193)
- Can chromosomal instability initiate tumorigenesis? (2005) (185)
- Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2 (2020) (185)
- The Origins and Implications of Intratumor Heterogeneity (2010) (185)
- Combination of a Novel Gene Expression Signature with a Clinical Nomogram Improves the Prediction of Survival in High-Risk Bladder Cancer (2012) (177)
- Risk prediction for late-stage ovarian cancer by meta-analysis of 1525 patient samples. (2014) (176)
- Genetic and phenotypic diversity in breast tumor metastases. (2014) (175)
- What does physics have to do with cancer? (2011) (169)
- A physical sciences network characterization of non-tumorigenic and metastatic cells (2013) (157)
- DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes (2011) (156)
- Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. (2017) (145)
- In situ single cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2+ breast cancer (2015) (138)
- Dynamics of colorectal cancer. (2005) (134)
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. (2018) (133)
- DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. (2011) (131)
- Mathematical models of cancer stem cells. (2008) (127)
- Evolutionary dynamics of invasion and escape. (2004) (123)
- Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer (2017) (121)
- Evolutionary pathways in BRCA1-associated breast tumors. (2012) (120)
- (A)Symmetric Stem Cell Replication and Cancer (2007) (120)
- Intratumor Heterogeneity in Evolutionary Models of Tumor Progression (2011) (118)
- CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation. (2015) (115)
- DNA replication timing and higher-order nuclear organization determine single nucleotide substitution patterns in cancer genomes (2013) (113)
- A mathematical framework to determine the temporal sequence of somatic genetic events in cancer (2010) (110)
- Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. (2020) (110)
- Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies (2009) (109)
- Evolutionary Theory of Cancer (2009) (106)
- Evolutionary dynamics of tumor suppressor gene inactivation. (2004) (104)
- Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the Effort (2015) (101)
- Linear Model of Colon Cancer Initiation (2004) (99)
- Evolutionary dynamics of escape from biomedical intervention (2003) (98)
- Evolution of resistance to cancer therapy. (2006) (96)
- The age incidence of chronic myeloid leukemia can be explained by a one-mutation model (2006) (94)
- Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments (2019) (91)
- The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma (2017) (90)
- Analysis of somatic microsatellite indels identifies driver events in human tumors (2017) (90)
- Evolution of resistance to anti-cancer therapy during general dosing schedules. (2010) (88)
- Aberration in DNA Methylation in B-Cell Lymphomas Has a Complex Origin and Increases with Disease Severity (2013) (87)
- Breast Tumors Maintain a Reservoir of Subclonal Diversity During Expansion (2021) (86)
- FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder (2014) (81)
- Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. (2013) (80)
- Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer (2018) (78)
- Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes. (2014) (78)
- Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms (2021) (77)
- Evolution of the cancer genome. (2012) (76)
- Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer (2012) (75)
- mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors. (2017) (74)
- A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell-related malignancy. (2010) (73)
- The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells (2015) (69)
- Stochastic dynamics of metastasis formation. (2006) (68)
- Eradication of Chronic Myeloid Leukemia Stem Cells: A Novel Mathematical Model Predicts No Therapeutic Benefit of Adding G-CSF to Imatinib (2009) (68)
- Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. (2020) (67)
- Somatic selection for and against cancer. (2003) (66)
- Population genetics of tumor suppressor genes. (2005) (66)
- The Therapeutic Implications of Plasticity of the Cancer Stem Cell Phenotype (2010) (65)
- The Evolution of Two Mutations During Clonal Expansion (2007) (65)
- Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells. (2011) (63)
- Fitness Conferred by BCR-ABL Kinase Domain Mutations Determines the Risk of Pre-Existing Resistance in Chronic Myeloid Leukemia (2011) (62)
- Evolutionary Modeling of Combination Treatment Strategies To Overcome Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer (2011) (60)
- Stochastic elimination of cancer cells (2003) (58)
- A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis (2012) (57)
- Evolutionary Dynamics of Intratumor Heterogeneity (2011) (56)
- Evolutionary dynamics of tumor progression with random fitness values. (2010) (56)
- The Warburg effect: persistence of stem-cell metabolism in cancers as a failure of differentiation (2018) (55)
- Stochastic dynamics of cancer initiation (2011) (53)
- Mathematical models of targeted cancer therapy (2006) (52)
- Pharmacokinetics and Drug Interactions Determine Optimum Combination Strategies in Computational Models of Cancer Evolution. (2017) (52)
- A progenitor cell origin of myeloid malignancies (2009) (52)
- Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance (2013) (50)
- Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma (2014) (48)
- A Differentiation-Based Phylogeny of Cancer Subtypes (2010) (47)
- Selection pressure exerted by imatinib therapy leads to disparate outcomes of imatinib discontinuation trials (2012) (46)
- The evolution of tumor metastases during clonal expansion. (2010) (46)
- Impact of HER2 heterogeneity on treatment response of early-stage HER2-positive breast cancer: phase II neoadjuvant clinical trial of T-DM1 combined with pertuzumab. (2021) (45)
- Some basic properties of immune selection. (2004) (45)
- Virus evolution within patients increases pathogenicity. (2005) (44)
- Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers. (2016) (43)
- ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells (2016) (43)
- Chronic Myeloid Leukemia Blast Crisis Arises from Progenitors (2007) (43)
- Genetic instability and the quasispecies model. (2006) (41)
- Genetic instability and clonal expansion. (2006) (39)
- Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages (2018) (39)
- Local Regulation of Homeostasis Favors Chromosomal Instability (2003) (37)
- Patterns of Proliferative Activity in the Colonic Crypt Determine Crypt Stability and Rates of Somatic Evolution (2013) (36)
- The Probable Cell of Origin of NF1- and PDGF-Driven Glioblastomas (2011) (35)
- The emergence of tumor metastases (2007) (34)
- Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells (2017) (34)
- A computational strategy to adjust for copy number in tumor Hi-C data (2016) (34)
- Optimization of radiation dosing schedules for proneural glioblastoma (2016) (34)
- Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution (2018) (33)
- Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations (2020) (33)
- Evolution: The good, the bad and the lonely (2002) (31)
- Mathematical modeling identifies optimum lapatinib dosing schedules for the treatment of glioblastoma patients (2018) (31)
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine (2018) (29)
- Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma (2018) (29)
- Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer (2020) (29)
- Correction: (A)Symmetric Stem Cell Replication and Cancer (2007) (28)
- Nuclear topology modulates the mutational landscapes of cancer genomes (2017) (27)
- Quantitative approaches to analyzing imatinib-treated chronic myeloid leukemia. (2007) (27)
- An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer (2015) (26)
- Reply: The long-term response to imatinib treatment of CML (2007) (26)
- Chromosomal instability and human cancer (2005) (25)
- Mutational Profile and Prognostic Relevance of Circulating Tumor Cells in Multiple Myeloma (2015) (25)
- On the Validity of Using Increases in 5-Year Survival Rates to Measure Success in the Fight against Cancer (2014) (25)
- Understanding tissue context influences on intratumour heterogeneity (2014) (24)
- Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease (2016) (24)
- DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors (2015) (23)
- Histone Modifications Are Associated with Transcript Isoform Diversity in Normal and Cancer Cells (2014) (23)
- A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1) (2008) (22)
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. (2019) (22)
- Dynamics of metastasis suppressor gene inactivation. (2006) (21)
- Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients (2015) (21)
- Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution (2016) (21)
- Accelerating massively parallel hemodynamic models of coarctation of the aorta using neural networks (2020) (21)
- The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer (2021) (20)
- Dynamics of chronic myeloid leukemia response to dasatinib, nilotinib, and high-dose imatinib (2014) (17)
- Progression signature underlies clonal evolution and dissemination of multiple myeloma. (2020) (17)
- Distance in cancer gene expression from stem cells predicts patient survival (2017) (15)
- Proceedings of the third international molecular pathological epidemiology (MPE) meeting (2016) (15)
- Epigenetic diversity in hematopoietic neoplasms. (2014) (15)
- Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells. (2016) (15)
- Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast (2021) (15)
- Stochastic Tunneling and Metastable States During the Somatic Evolution of Cancer (2014) (14)
- A Race between Tumor Immunoescape and Genome Maintenance Selects for Optimum Levels of (epi)genetic Instability (2012) (14)
- A phase I study of twice weekly pulse dose and daily low dose erlotinib as initial treatment for patients (pts) with EGFR-mutant lung cancers. (2015) (13)
- Circadian clock effects on cellular proliferation: Insights from theory and experiments. (2020) (12)
- Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer (2021) (12)
- Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML (2021) (12)
- Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells (2021) (12)
- Computational Model of Progression to Multiple Myeloma Identifies Optimum Screening Strategies (2018) (11)
- Mutational dynamics and transmission properties of SARS-CoV-2 superspreading events in Austria (2020) (11)
- Correction: Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies (2009) (10)
- Stochastic Tunneling of Two Mutations in a Population of Cancer Cells (2013) (10)
- Progression signature underlies clonal evolution and dissemination of Multiple Myeloma (2019) (8)
- FGFR 3 expression in primary and metastatic urothelial carcinoma of the bladder (2014) (8)
- Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk. (2017) (8)
- Phase II study of ruxolitinib , a selective JAK 1 / 2 inhibitor , in patients with metastatic triple-negative breast cancer (2018) (8)
- Topological isolation of developmental regulators in mammalian genomes (2021) (8)
- Safety and efficacy of pulsed imatinib with or without G‐CSF versus continuous imatinib in chronic phase chronic myeloid leukaemia patients at 5 years follow‐up (2013) (8)
- Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance (2020) (8)
- The sciences converge to fight cancer (2012) (7)
- SIApopr: a computational method to simulate evolutionary branching trees for analysis of tumor clonal evolution (2017) (7)
- Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in JAK2-mutant myeloproliferative neoplasms (2020) (7)
- Reply to Parsons: Many tumor types follow the monoclonal model of tumor initiation (2011) (7)
- Clonal Hematopoiesis Associated with Adverse Outcomes Following Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma (2016) (6)
- Fitness variation in isogenic populations leads to a novel evolutionary mechanism for crossing fitness valleys (2018) (6)
- Response to comment on “Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2” (2021) (6)
- Stochastic Evolution of Pancreatic Cancer Metastases During Logistic Clonal Expansion. (2019) (6)
- ESTIpop: a computational tool to simulate and estimate parameters for continuous-time Markov branching processes (2020) (6)
- Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis. (2011) (6)
- A Quantitative Paradigm for Decision-Making in Precision Oncology. (2021) (5)
- Computational modeling of pancreatic cancer patients receiving FOLFIRINOX and gemcitabine-based therapies identifies optimum intervention strategies (2019) (5)
- A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives glioblastoma progression (2022) (5)
- Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Hematopoietic Stem Cells in JAK2-Mutant Myeloproliferative Neoplasms (2020) (5)
- Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma (2021) (4)
- DIFFpop: a stochastic computational approach to simulate differentiation hierarchies with single cell barcoding (2019) (3)
- A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing (2017) (2)
- Directional Evolution of Virus Within a Host Under Immune Selection (2007) (2)
- Breast cancer prevention by short-term inhibition of TGFβ signaling (2022) (2)
- Abstract 3961: Computational modeling of pancreatic cancer reveals growth and dissemination kinetics and suggests optimum treatment strategies (2012) (2)
- Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution (2018) (2)
- How Does Large-Scale Genomic Analysis Shape Our Understanding of COVID Variants in Real Time? (2021) (2)
- Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms (2020) (2)
- Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients (2022) (2)
- FGFR3 protein expression and gene mutation in primary and metastatic urothelial carcinoma (UC) tumors. (2012) (2)
- Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease. (2023) (2)
- Juliann Chmielecki with Evolutionary Cancer Modeling Small Cell Lung Cancer − Optimization of Dosing for EGFR-Mutant Non (2011) (1)
- Peroxisome proliferator-activated receptor gamma (PPARG) gene amplifications in urothelial carcinoma (UC). (2013) (1)
- Meta-analysis of public microarray databases for prognostic and predictive gene signatures of late-stage ovarian cancer. (2014) (1)
- DLBCL associated with different clinical outcomes Variability in DNA methylation defines novel epigenetic subgroups of (2014) (1)
- A computational model of MGUS progression to Multiple Myeloma identifies optimum screening strategies and their effects on mortality (2017) (1)
- Molecular Responses to Dasatinib and Nilotinib in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP). (2008) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia (2021) (1)
- Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model (2017) (1)
- Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses (2021) (1)
- Epigenetic Deregulation In Relapsed Acute Myeloid Leukemia (2013) (1)
- Epigenetic Profiling of Primary DLBCLs Reveals Novel DNA Methylation-Based Clusters and New Underlying Mechanisms of Lymphomagenesis (2011) (1)
- Immunology tomorrow (2002) (1)
- Abstract PR09: Extracellular stiffness cues drive spatial reorganization of the genome to globally constrain RNA abundance (2015) (1)
- Mathematical Optimization of JAK Inhibitor Dose and Scheduling for MPN Patients (2014) (1)
- Abstract GS3-07: GS3-07 Clonal evolution and mechanisms of acquired resistance to CDK4/6 inhibitors in ER-wild type and ER-mutant breast cancer (2023) (1)
- JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States (2022) (1)
- Analyzing the association of SCNA boundaries with replication timing (2012) (1)
- Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages (2018) (1)
- Genomic characterization of metastatic urothelial carcinoma. (2013) (1)
- Single-cell genetic heterogeneity linked to immune infiltration in glioblastoma (2021) (1)
- Heterogeneity in evolutionary models of tumor progression (2010) (1)
- In Vivo Analysis of Clonal Evolution of Multiple Myeloma (2016) (1)
- Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq (2018) (1)
- In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies (2022) (1)
- Abstract PR02: Minor clones can drive polyclonal metastasis by affecting immune microenvironment (2018) (0)
- Abstract LB-26: A mathematical methodology for determining the temporal order of pathway alterations in cancer (2011) (0)
- PATH-29. GLIOBLASTOMA TUMOR CLASSIFICATION BASED ON SPATIAL ANALYSIS OF ONCOGENIC AMPLIFICATIONS AND PROTEIN EXPRESSION (2021) (0)
- Mathematical Models of Cancer Evolution and Cure (2015) (0)
- Abstract A21: Proteomic profiling to elucidate intratumoral heterogeneity and cancer evolution in lung cancer (2015) (0)
- Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo (2018) (0)
- Optimization of radiation dosing schedules for proneural glioblastoma (2015) (0)
- Identification of a Gene Expression Signature Characterizing Clonal Fitness and Dominance in Vivo in a Murine Model of MLL-AF9 Leukemia (2014) (0)
- 397 Deep myeloid cell profiling provides new insights into modulators of CAR T cell expansion in patients with solid tumor malignancies (2022) (0)
- Bladder Cancer Nomogram Improves the Prediction of Survival in High-Risk Combination of a Novel Gene Expression Signature with a Clinical (2012) (0)
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine (2018) (0)
- MA 12.06 Using Population Dynamics Mathematical Modeling to Optimize an Intermittent Dosing Regimen for Osimertinib in EGFR-Mutant NSCLC (2017) (0)
- T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation (2023) (0)
- Title: Evolutionary pathways in BRCA1-associated breast tumors (2012) (0)
- Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer (2018) (0)
- Mechanisms of Response and Resistance to Combination Decitabine and Ipilimumab for Transplant Naïve and Post-Transplant AML/MDS (2022) (0)
- Ablated intestinal stem cells recover predominantly by ASCL2-dependent dedifferentiation of their recent progeny (2020) (0)
- Abstract 2344: 3D extracellular stiffness cues drive localized changes in gene expression (2014) (0)
- P1.03-003 The Warburg Effect: Persistence of Stem Cell Metabolism in Lung Cancer as Failure of Differentiation (2017) (0)
- Optimization of radiation schedules for proneural gliomas via mathematical modeling (2014) (0)
- Abstract IA05: Evolution of glioblastoma subtypes (2015) (0)
- A Feasibility Study using Image-based Parallel Modeling for Treatment Planning (2016) (0)
- Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation (2022) (0)
- Transcriptional differences between JAK2-V617F and wild-type bone marrow cells in myeloproliferative neoplasm patients. (2021) (0)
- Abstract 2355: Risk prediction for late-stage ovarian cancer by meta-analysis of 1,525 patient samples (2014) (0)
- Abstract LB-310: Single cell genome sequencing reveals clonal stability and diversity in breast cancer (2014) (0)
- Abstract PR05: The effect of chemotherapy on HER2+ breast cancer heterogeneity measured by STAR-FISH: Detection of PIK3CA mutation and HER2 amplification at single-cell level in situ (2016) (0)
- resistance lines identifies spectrum of DNA changes associated with drug inhibitor-sensitive and-resistant EGFR mutant lung cancer cell Next-generation sequencing of paired tyrosine kinase Material Supplemental (2013) (0)
- Abstract LB-280: The landscape of somatic microsatellite indels across cancer: detection and identification of driver events (2017) (0)
- Abstract A018: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping (2022) (0)
- Abstract PO-133: Breast tumors maintain a reservoir of subclonal diversity during primary expansion (2020) (0)
- Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer (2020) (0)
- Abstract A15: Immune-related changes in breast cancer tumor evolution (2018) (0)
- Author Correction: Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer (2022) (0)
- P2.01-026 A Mass Spectrometry Based Stem Cell-Oriented Phylogeny of Intra-Tumoral NSCLC Subclones: Topic: Proteins in Lung Cancer and Proteomics (2017) (0)
- Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML (2021) (0)
- 362 Defining T cell exhaustion and memory correlates of GD2 CAR T cell expansion in pediatric patients with solid tumor malignancies (2022) (0)
- In Vivo Profiling of Leukemic Stem Cell Fitness Identifies Therapeutically Actionable Determinants of Growth (2018) (0)
- Proceedings of the third international molecular pathological epidemiology (MPE) meeting (2017) (0)
- 314. Mathematical Modeling of Erythrocyte Chimerism Informs Clinical Strategies for Sickle Cell Disease (2016) (0)
- Imaging , Diagnosis , Prognosis Combination of a Novel Gene Expression Signature with a Clinical Nomogram Improves the Prediction of Survival in High-Risk Bladder Cancer (2012) (0)
- Abstract PR16: Spatio-temporal heterogeneity in the tumor microenvironment influences the evolutionary dynamics of drug resistance (2015) (0)
- GENE-04. THE ONCOGENIC FUNCTIONS OF YAP1-GENE FUSIONS CAN BE INHIBITED BY DISRUPTION OF YAP1-TEAD INTERACTION (2019) (0)
- Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis (2022) (0)
- 1361 GENE EXPRESSION PROFILES IN PATIENTS WITH UROTHELIAL CANCER UNDERGOING RADICAL CYSTECTOMY (2011) (0)
- Abstract A82: Prognostic relevance and genomic profile of circulating tumor cells in multiple myeloma (2015) (0)
- therapy reveal treatment effects on leukemic stem cells Dynamics of chronic myeloid leukemia response to long-term targeted (2011) (0)
- Analysis of pressure gradient across aortic stenosis with massively parallel computational simulations (2014) (0)
- Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma. (2023) (0)
- Abstract 2847: High complexity barcoding to study clonal dynamics in response to cancer therapy (2015) (0)
- Abstract A21: Characterization of the immune environment in the in situ to invasive breast carcinoma transition (2018) (0)
- Modelling BCR-ABL1 Dynamics in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) during Frontline Therapy with High-Dose Imatinib, Nilotinib, or Dasatinib. (2008) (0)
- Abstract A38: Cd70 genetic perturbation limits the development of an effective CD8+ T-cell immune response to Bcl6-driven diffuse large B-cell lymphoma (2022) (0)
- Abstract C47: Inference of tumor evolution during chemotherapy by computational modeling and single cell analysis of diversity. (2013) (0)
- Brief report: Combination of Osimertinib and Dacomitinib to mitigate primary and acquired resistance in EGFR-mutant lung adenocarcinomas. (2023) (0)
- A genome-wide, in vivo dropout CRISPR screen in acute myeloid leukemia (2017) (0)
- DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors (2015) (0)
- Designing optimal allocations for cancer screening using queuing network models (2022) (0)
- CXCR 4 Regulates Extra-M edullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation Graphical (2015) (0)
- Spatial modeling of the brain tumor perivascular niche (2012) (0)
- Abstract B16: Mathematical modeling identifies optimum palbociclib dosing schedules for the treatment of estrogen receptor-positive (ER+) breast cancer patients (2020) (0)
- External validation of somatic copy number alteration (SCNA) at chromosome 1q23.3 in advanced urothelial carcinoma (UC). (2012) (0)
- P3.01-059 A Stem-Cell Oriented Phylogeny of Non-Small Cell Lung Cancers: Topic: Stem Cells in Lung Cancer (2017) (0)
- Abstract IA013: Genetic heterogeneity and tumor microenvironment in glioblastoma (2022) (0)
- Fitness variation in isogenic populations leads to a novel evolutionary mechanism for crossing fitness valleys (2018) (0)
- Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity. (2022) (0)
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