Fred s. Apple
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Cardiology
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Fred s. Apple's Degrees
- Doctorate Cardiology Stanford University
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(Suggest an Edit or Addition)Fred s. Apple's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. (2000) (4196)
- Third universal definition of myocardial infarction. (2012) (4123)
- Universal definition of myocardial infarction. (2015) (2234)
- Cardiac Troponin I A Marker With High Specificity for Cardiac Injury (1993) (1205)
- Liberal or restrictive transfusion in high-risk patients after hip surgery. (2011) (1169)
- Ferritin: a cytoprotective antioxidant strategem of endothelium. (1992) (1092)
- Third universal definition of myocardial infarction. (2012) (751)
- Analytical characteristics of high-sensitivity cardiac troponin assays. (2012) (733)
- National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. (2007) (720)
- National Academy of Clinical Biochemistry Standards of Laboratory Practice: recommendations for the use of cardiac markers in coronary artery diseases. (1999) (707)
- Cardiac troponin and outcome in acute heart failure. (2008) (679)
- Biomarkers in acute cardiac disease: the present and the future. (2006) (663)
- It's time for a change to a troponin standard. (2000) (652)
- Predictive Value of Cardiac Troponin I and T for Subsequent Death in End-Stage Renal Disease (2002) (576)
- Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. (2012) (523)
- Biochemical Mechanisms for Oxygen Free Radical Formation During Exercise (1990) (515)
- Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. (2005) (467)
- A new season for cardiac troponin assays: it's time to keep a scorecard. (2009) (445)
- Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1 (2007) (433)
- High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study (2015) (409)
- European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: how to use existing assays clinically and for clinical trials. (2002) (400)
- Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization. (1998) (397)
- Evaluation of imprecision for cardiac troponin assays at low-range concentrations. (2004) (394)
- National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biochemical markers of acute coronary syndromes. (2007) (376)
- High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study (2015) (372)
- Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology/American College of Cardiology consensus recommendations. (2003) (336)
- Cardiac troponin-I is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue. (1995) (326)
- Multicenter evaluation of the Roche NT-proBNP assay and comparison to the Biosite Triage BNP assay. (2003) (310)
- Characteristics of an Albumin Cobalt Binding Test for assessment of acute coronary syndrome patients: a multicenter study. (2001) (284)
- Evidence for functional heterogeneity of circulating B-type natriuretic peptide. (2007) (270)
- Cardiac Troponin Assays: Guide to Understanding Analytical Characteristics and Their Impact on Clinical Care. (2017) (270)
- National Academy of Clinical Biochemistry laboratory medicine practice guidelines: use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure. (2007) (255)
- Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. (2011) (252)
- Influence of population selection on the 99th percentile reference value for cardiac troponin assays. (2012) (239)
- Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease: evidence of cardiac troponin T expression in skeletal muscle. (1997) (238)
- Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death. (2004) (237)
- Bedside Multimarker Testing for Risk Stratification in Chest Pain Units: The Chest Pain Evaluation by Creatine Kinase-MB, Myoglobin, and Troponin I (CHECKMATE) Study (2001) (231)
- Cardiac troponin T composition in normal and regenerating human skeletal muscle. (1997) (227)
- Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events. (2009) (224)
- Quality Specifications for Cardiac Troponin Assays (2001) (218)
- IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays. (2015) (218)
- Cardiac troponin T isoforms expressed in renal diseased skeletal muscle will not cause false-positive results by the second generation cardiac troponin T assay by Boehringer Mannheim. (1998) (212)
- Improved detection of minor ischemic myocardial injury with measurement of serum cardiac troponin I. (1997) (208)
- Simultaneous rapid measurement of whole blood myoglobin, creatine kinase MB, and cardiac troponin I by the triage cardiac panel for detection of myocardial infarction. (1999) (207)
- High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial (2018) (201)
- Definitions for Acute Coronary Heart Disease in Epidemiology and Clinical Research Studies (2003) (194)
- Cardiac troponin-T immunoassay for diagnosis of acute myocardial infarction. (1994) (189)
- Quality specifications for B-type natriuretic peptide assays. (2005) (187)
- Release characteristics of cardiac biomarkers and ischemia-modified albumin as measured by the albumin cobalt-binding test after a marathon race. (2002) (185)
- Myocardial infarction redefined: role of cardiac troponin testing. (2001) (184)
- Use of the Centaur TnI-Ultra assay for detection of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. (2008) (175)
- National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: Analytical issues for biochemical markers of acute coronary syndromes. (2007) (168)
- Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction). (2013) (166)
- Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome (2017) (159)
- The brain natriuretic peptide (BNP) precursor is the major immunoreactive form of BNP in patients with heart failure. (2007) (156)
- The global need to define normality: the 99th percentile value of cardiac troponin. (2014) (154)
- High-sensitivity cardiac troponin T in prediction and diagnosis of myocardial infarction and long-term mortality after noncardiac surgery. (2013) (153)
- Cardiac troponin T alterations in myocardium and serum of rats after stressful, prolonged intense exercise. (2000) (146)
- Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB. (1999) (145)
- Use of Biochemical Markers in Acute Coronary Syndromes. IFCC Scientific Division, Committee on Standardization of Markers of Cardiac Damage (1999) (142)
- Supply/demand type 2 myocardial infarction: should we be paying more attention? (2014) (141)
- Being rational about (im)precision: a statement from the Biochemistry Subcommittee of the Joint European Society of Cardiology/American College of Cardiology Foundation/American Heart Association/World Heart Federation Task Force for the definition of myocardial infarction. (2010) (140)
- Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction. (2005) (140)
- Cardiac troponin I and T alterations in dog hearts with myocardial infarction: correlation with infarct size. (1998) (138)
- Effect of sprint cycle training on activities of antioxidant enzymes in human skeletal muscle. (1996) (134)
- Cross-reactivity of BNP, NT-proBNP, and proBNP in commercial BNP and NT-proBNP assays: preliminary observations from the IFCC Committee for Standardization of Markers of Cardiac Damage. (2008) (133)
- Early diagnostic efficiency of cardiac troponin I and Troponin T for acute myocardial infarction. (1997) (132)
- Myocardial tissue troponins T and I. An immunohistochemical study in experimental models of myocardial ischemia. (2003) (130)
- Etiology of sudden death in the community: results of anatomical, metabolic, and genetic evaluation. (2010) (130)
- Prognostic value of serum cardiac troponin I and T in chronic dialysis patients: a 1-year outcomes analysis. (1997) (127)
- RNA expression of cardiac troponin T isoforms in diseased human skeletal muscle. (1999) (126)
- Standardization of cardiac troponin I assays: round Robin of ten candidate reference materials. (2001) (116)
- Clinical and analytical standardization issues confronting cardiac troponin I. (1999) (115)
- Multicenter evaluation of an automated assay for troponin I. (2002) (115)
- Implementation of serum cardiac troponin I as marker for detection of acute myocardial infarction. (1999) (114)
- Propofol-associated rhabdomyolysis with cardiac involvement in adults: chemical and anatomic findings. (2000) (114)
- Human and canine cardiac troponin T and creatine kinase-MB distribution in normal and diseased myocardium. Infarct sizing using serum profiles. (1995) (112)
- Multicenter clinical and analytical evaluation of the AxSYM troponin-I immunoassay to assist in the diagnosis of myocardial infarction. (1999) (112)
- Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) (2006) (109)
- National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Clinical utilization of cardiac biomarker testing in heart failure. (2008) (108)
- Immunodetection of glycosylated NT-proBNP circulating in human blood. (2008) (108)
- Effect of population selection on 99th percentile values for a high sensitivity cardiac troponin I and T assays. (2013) (105)
- Predictors and outcomes of a perioperative myocardial infarction following elective vascular surgery in patients with documented coronary artery disease: results of the CARP trial. (2008) (104)
- Cardiac troponin I measurement with the ACCESS immunoassay system: analytical and clinical performance characteristics. (1998) (102)
- Bedside multimarker testing for risk stratification in chest pain units: The chest pain evaluation by creatine kinase-MB, myoglobin, and troponin I (CHECKMATE) study. (2001) (102)
- Toward standardization of cardiac troponin I measurements part II: assessing commutability of candidate reference materials and harmonization of cardiac troponin I assays. (2006) (98)
- Profile of creatine kinase isoenzymes in skeletal muscles of marathon runners. (1984) (97)
- Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease. (2012) (97)
- High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction (2019) (96)
- Cardiac troponin and creatine kinase MB monitoring during in-hospital myocardial reinfarction. (2005) (96)
- Type 1 and 2 Myocardial Infarction and Myocardial Injury: Clinical Transition to High-Sensitivity Cardiac Troponin I. (2017) (96)
- Cardiac biomarkers for detection of myocardial infarction: perspectives from past to present. (2004) (95)
- Multiple biomarker use for detection of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. (2007) (94)
- Clinical implications of a recent adjustment to the high-sensitivity cardiac troponin T assay: user beware. (2012) (92)
- Machine Learning to Predict the Likelihood of Acute Myocardial Infarction (2019) (91)
- Acute myocardial infarction and coronary reperfusion. Serum cardiac markers for the 1990s. (1992) (91)
- Patient selection for high sensitivity cardiac troponin testing and diagnosis of myocardial infarction: prospective cohort study (2017) (90)
- Cardiac troponin changes to distinguish type 1 and type 2 myocardial infarction and 180-day mortality risk (2014) (88)
- Analytical characteristics of commercial cardiac troponin I and T immunoassays in serum from rats, dogs, and monkeys with induced acute myocardial injury. (2008) (86)
- Effect of Neprilysin Inhibition on Various Natriuretic Peptide Assays. (2019) (85)
- National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biomarkers of heart failure. (2007) (85)
- Time course of serum protein changes after strenuous exercise of the forearm flexors. (1992) (81)
- Defining the serum 99th percentile in a normal reference population measured by a high-sensitivity cardiac troponin I assay. (2010) (80)
- Creatine kinase isoenzyme activities in men and women following a marathon race. (1985) (79)
- [Fourth universal definition of myocardial infarction (2018)]. (2018) (78)
- Assessment of the multiple-biomarker approach for diagnosis of myocardial infarction in patients presenting with symptoms suggestive of acute coronary syndrome. (2009) (77)
- Counterpoint: Standardization of cardiac troponin I assays will not occur in my lifetime. (2012) (76)
- Biochemical markers of cardiac injury in normal, surviving septic, or nonsurviving septic neonatal foals. (2005) (76)
- Evaluation of a point-of-care assay for cardiac markers for patients suspected of acute myocardial infarction. (2004) (76)
- Analytical performance of the i-STAT cardiac troponin I assay. (2004) (76)
- Enzymatic estimation of skeletal muscle damage by analysis of changes in serum creatine kinase. (1988) (74)
- Rates of positive cardiac troponin I and creatine kinase MB mass among patients hospitalized for suspected acute coronary syndromes. (2004) (72)
- Decreased patient charges following implementation of point-of-care cardiac troponin monitoring in acute coronary syndrome patients in a community hospital cardiology unit. (2006) (70)
- National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine practice guidelines: Analytical issues for biomarkers of heart failure. (2008) (70)
- Myocardial Injury in the Era of High-Sensitivity Cardiac Troponin Assays: A Practical Approach for Clinicians. (2019) (69)
- Diagnosis of type 1 and type 2 myocardial infarction using a high-sensitivity cardiac troponin I assay with sex-specific 99th percentiles based on the third universal definition of myocardial infarction classification system. (2015) (69)
- B-type natriuretic peptide (BNP) and N-terminal pro-BNP in obese patients without heart failure: relationship to body mass index and gastric bypass surgery. (2006) (67)
- Early monitoring of serum cardiac troponin I for assessment of coronary reperfusion following thrombolytic therapy. (1996) (66)
- Results from a multicenter evaluation of the 4th generation Elecsys Troponin T assay. (2007) (65)
- Present and Future of Cardiac Troponin in Clinical Practice: A Paradigm Shift to High-Sensitivity Assays. (2016) (63)
- Myocardial Infarction Risk Stratification With a Single Measurement of High-Sensitivity Troponin I. (2019) (63)
- High-sensitivity cardiac troponin assays for cardiovascular risk stratification in the general population. (2020) (63)
- Methadone-related deaths in Hennepin County, Minnesota: 1992-2002. (2003) (62)
- Cardiac isoenzymes in healthy Holstein calves and calves with experimentally induced endotoxemia. (2008) (60)
- Increased cardiac troponin I as measured by a high-sensitivity assay is associated with high odds of cardiovascular death: the Minnesota Heart Survey. (2012) (60)
- A translational approach to detecting drug-induced cardiac injury with cardiac troponins: consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute. (2009) (59)
- Sex-Specific 99th Percentile Upper Reference Limits for High Sensitivity Cardiac Troponin Assays Derived Using a Universal Sample Bank. (2020) (58)
- Postmortem redistribution of fentanyl in blood. (2010) (58)
- Point-of-care i-STAT cardiac troponin I for assessment of patients with symptoms suggestive of acute coronary syndrome. (2006) (58)
- High sensitivity, contemporary and point-of-care cardiac troponin assays: educational aids developed by the IFCC Committee on Clinical Application of Cardiac Bio-Markers (2019) (57)
- Poor iron status of women runners training for a marathon. (1986) (57)
- International survey on the use of cardiac markers. (2001) (56)
- Cardiac troponin I and T alterations in hearts with severe left ventricular remodeling. (1997) (56)
- Variations in vitreous humor chemical values as a result of instrumentation. (1985) (56)
- Specificity of B-Type Natriuretic Peptide Assays: Cross-Reactivity with Different BNP, NT-proBNP, and proBNP Peptides. (2017) (56)
- Misleading hyponatremia due to hyperlipemia: a method-dependent error. (1981) (55)
- Cardiac troponin assays: a review of quantitative point-of-care devices and their efficacy in the diagnosis of myocardial infarction (2015) (55)
- Cocaine, cocaine metabolite, and ethanol concentrations in postmortem blood and vitreous humor. (2000) (55)
- Evidence-based implementation of free phenytoin therapeutic drug monitoring. (2000) (54)
- Mitochondrial creatine kinase activity alterations in skeletal muscle during long-distance running. (1986) (54)
- Analysis of the Albumin cobalt Binding (ACBTM) test as an adjunct to cardiac troponin I for the early detection of acute myocardial infarction (2007) (53)
- Measurement of chemical analytes in vitreous humor: stability and precision studies. (2004) (53)
- The applied statistical approach highly influences the 99th percentile of cardiac troponin I. (2016) (52)
- Creatinine clearance: enzymatic vs Jaffé determinations of creatinine in plasma and urine. (1986) (51)
- Clinical evaluation of the first medical whole blood, point-of-care testing device for detection of myocardial infarction. (2000) (51)
- Renal Dysfunction Influences the Diagnostic and Prognostic Performance of High-Sensitivity Cardiac Troponin I. (2017) (51)
- Creatine kinase isoenzyme MM variants in skeletal muscle and plasma from marathon runners. (1986) (51)
- Comparison of serum creatine kinase and creatine kinase MB activities post marathon race versus post myocardial infarction. (1984) (50)
- Lipase and pancreatic amylase activities in tissues and in patients with hyperamylasemia. (1991) (50)
- Early detection of skeletal muscle injury by assay of creatine kinase MM isoforms in serum after acute exercise. (1988) (50)
- Sodium measurements in multiple myeloma: two techniques compared. (1982) (49)
- Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays (2014) (49)
- Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays (2014) (49)
- Relationship between blood alcohol concentration and observable symptoms of intoxication in patients presenting to an emergency department. (2013) (49)
- Improving Prediction of Postoperative Myocardial Infarction With High-Sensitivity Cardiac Troponin T and NT-proBNP (2017) (48)
- How Well Do Laboratories Adhere to Recommended Clinical Guidelines for the Management of Myocardial Infarction: The CARdiac MArker Guidelines Uptake in Europe Study (CARMAGUE). (2016) (48)
- Serum and plasma cardiac troponin I 99th percentile reference values for 3 2nd-generation assays. (2007) (48)
- Serum enzyme changes during marathon training. (1983) (48)
- Liver and blood postmortem tricyclic antidepressant concentrations. (1988) (48)
- Cocaine-induced erythrocytosis and increase in von Willebrand factor: evidence for drug-related blood doping and prothrombotic effects. (1999) (48)
- Single High-Sensitivity Cardiac Troponin I to Rule Out Acute Myocardial Infarction. (2017) (48)
- Proposals from IFCC Committee on Standardization of Markers of Cardiac Damage (C-SMCD): recommendations on use of biochemical markers of cardiac damage in acute coronary syndromes. (1999) (47)
- High-sensitivity cardiac troponin: hype, help, and reality. (2010) (46)
- Rapid Rule-Out of Acute Myocardial Injury Using a Single High-Sensitivity Cardiac Troponin I Measurement. (2017) (45)
- High-sensitivity cardiac troponin assays and unstable angina (2018) (45)
- CK and LD isozymes in human single muscle fibers in trained athletes. (1989) (44)
- Proposals from the IFCC Committee on Standardization of Markers of Cardiac Damage (C-SMCD): strategies and concepts on standardization of cardiac marker assays. (1999) (44)
- Diagnostic performance of four point of care cardiac troponin I assays to rule in and rule out acute myocardial infarction. (2013) (44)
- Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research (2016) (44)
- Why all the struggle about CK-MB and PCI? (2012) (44)
- Creatine kinase-MB isoenzyme adaptations in stressed human skeletal muscle of marathon runners. (1984) (43)
- Relationship between direct-potentiometric and flame-photometric measurement of sodium in blood. (1982) (43)
- Cardiac troponin, CK-MB and myoglobin for the early detection of acute myocardial infarction and monitoring of reperfusion following thrombolytic therapy. (1995) (43)
- Postmortem tricyclic antidepressant concentrations: assessing cause of death using parent drug to metabolite ratio. (1989) (42)
- Prognostic Value of Serial Changes in High-Sensitivity Cardiac Troponin I and T over 3 Months Using Reference Change Values in Hemodialysis Patients. (2016) (42)
- Prevention of analytical false-positive increases of cardiac troponin I on the Stratus II analyzer. (1997) (42)
- The Specificity of Biochemical Markers of Cardiac Damage: a Problem Solved (1999) (42)
- Creatine kinase-MB isoenzyme adaptations in stressed human skeletal muscle of marathon runners (1985) (42)
- Optimum blood collection intervals for B-type natriuretic peptide testing in patients with heart failure. (2004) (41)
- Cardiac troponin I and creatine kinase-MB mass to rule out myocardial injury in hospitalized patients with renal insufficiency. (1998) (40)
- Serum 99th percentile reference cutoffs for seven cardiac troponin assays. (2004) (40)
- Creatine kinase isoforms following isometric exercise (1987) (40)
- Discordance between ICD-Coded Myocardial Infarction and Diagnosis according to the Universal Definition of Myocardial Infarction. (2017) (40)
- Assessment of left ventricular function using serum cardiac troponin I measurements following myocardial infarction. (1998) (39)
- Analyses of creatine kinase isoenzymes and isoforms in serum to detect reperfusion after acute myocardial infarction. (1987) (38)
- Diagnostic Performance of High Sensitivity Compared with Contemporary Cardiac Troponin I for the Diagnosis of Acute Myocardial Infarction. (2017) (38)
- Total Analytic Error for Low Cardiac Troponin Concentrations (≤10 ng/L) by Use of a High-Sensitivity Cardiac Troponin Assay. (2017) (38)
- Expression of cardiac troponin T isoforms in skeletal muscle of renal disease patients will not cause false-positive serum results by the second generation cardiac troponin T assay. (1998) (37)
- Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation—Effects on histopathology and organ function* (2006) (37)
- Outcomes of hospitalized patients with non-acute coronary syndrome and elevated cardiac troponin level. (2011) (37)
- Novel immunoassay for quantification of brain natriuretic peptide and its precursor in human blood. (2008) (37)
- Performance characteristics of the ARCHITECT Galectin-3 assay. (2013) (36)
- Cardiac troponin testing in the acute care setting: ordering, reporting, and high sensitivity assays--an update from the Canadian society of clinical chemists (CSCC). (2011) (36)
- Incidence of Undetectable, Measurable, and Increased Cardiac Troponin I Concentrations Above the 99th Percentile Using a High-Sensitivity vs a Contemporary Assay in Patients Presenting to the Emergency Department. (2016) (35)
- Delta changes for optimizing clinical specificity and 60-day risk of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome utilizing the ADVIA Centaur TnI-Ultra assay. (2012) (35)
- Performance of Novel High-Sensitivity Cardiac Troponin I Assays for 0/1-Hour and 0/2- to 3-Hour Evaluations for Acute Myocardial Infarction: Results From the HIGH-US Study. (2020) (35)
- Cardiac Troponin I and T Concentrations in Patients with Cocaine-Associated Chest Pain (1996) (35)
- Fentanyl postmortem redistribution: preliminary findings regarding the relationship among femoral blood and liver and heart tissue concentrations. (2008) (35)
- N-terminal and C-terminal fragments of IGFBP-4 as novel biomarkers for short-term risk assessment of major adverse cardiac events in patients presenting with ischemia. (2012) (34)
- Cardiac Biomarkers (2015) (33)
- Longitudinal studies of cardiac troponin I in a large cohort of healthy children. (2012) (33)
- Expression of creative kinase M and B mRNAs in treadmill trained rat skeletal muscle (1994) (31)
- Iron status of active women and the effect of running a marathon on bowel function and gastrointestinal blood loss. (1991) (29)
- Clinical and analytical review of ischemia-modified albumin measured by the albumin cobalt binding test. (2005) (28)
- Assessment of the diagnostic accuracy of the TDx-FLM II to predict fetal lung maturity. (2002) (27)
- Delta cardiac troponin values in practice: are we ready to move absolutely forward to clinical routine? (2012) (27)
- Skeletal muscle lactate dehydrogenase isozyme alterations in men and women marathon runners. (1986) (27)
- Cardiac troponin T is not detected in Western blots of diseased renal tissue. (2001) (26)
- Placental growth factor and B-type natriuretic peptide as independent predictors of risk from a multibiomarker panel in suspected acute coronary syndrome (Acute Risk and Related Outcomes Assessed With Cardiac Biomarkers [ARROW]) study. (2011) (26)
- Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB) (2019) (26)
- Marathoner's heart? (2006) (26)
- Use of the bioMérieux VIDAS troponin I ultra assay for the diagnosis of myocardial infarction and detection of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. (2008) (26)
- Sex-specific 99th percentiles derived from the AACC Universal Sample Bank for the Roche Gen 5 cTnT assay: Comorbidities and statistical methods influence derivation of reference limits. (2017) (25)
- Effectiveness of practices for improving the diagnostic accuracy of Non ST Elevation Myocardial Infarction in the Emergency Department: A Laboratory Medicine Best Practices™ systematic review. (2015) (25)
- Central versus local adjudication of myocardial infarction in a cardiac biomarker trial. (2013) (24)
- Unbound free fatty acid concentrations are increased in cardiac ischemia (2004) (24)
- Prognostic value of the Ortho Vitros cardiac troponin I assay in patients with symptoms of myocardial ischemia. Risk stratification using European Society of Cardiology/American College of Cardiology recommended cutoff values. (2003) (24)
- Postmortem blood free and total morphine concentrations in medical examiner cases. (2001) (24)
- High-sensitivity cardiac troponin assays: isn't it time for equality? (2014) (24)
- False-positive AxSYM cardiac troponin I results in a 53-year-old woman. (2002) (24)
- High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction (2021) (23)
- Diagnostic use of CK-MM and CK-MB isoforms for detecting myocardial infarction. (1989) (23)
- Use of objective evidence of myocardial ischemia to facilitate the diagnostic and prognostic distinction between type 2 myocardial infarction and myocardial injury (2018) (23)
- Monitoring plasma cardiac troponin I for the detection of myocardial injury after percutaneous transluminal coronary angioplasty. (2000) (22)
- Use of the HEART Pathway with high sensitivity cardiac troponins: A secondary analysis. (2017) (22)
- Clinical and analytical evaluation of two immunoassays for direct measurement of creatine kinase MB with monoclonal anti-CK-MB antibodies. (1988) (22)
- Multi-center validation of the Response Biomedical Corporation RAMP NT-proBNP assay with comparison to the Roche Diagnostics GmbH Elecsys proBNP assay. (2007) (22)
- High-sensitivity cardiac troponin for screening large populations of healthy people: is there risk? (2011) (22)
- Expression of creatine kinase M and B mRNAs in treadmill trained rat skeletal muscle. (1994) (22)
- Unraveling N-terminal pro-B-type natriuretic peptide: another piece to a very complex puzzle in heart failure patients. (2015) (21)
- Multiple biomarkers including cardiac troponins T and I measured by high-sensitivity assays, as predictors of long-term mortality in patients with chronic renal failure who underwent dialysis. (2015) (21)
- The state of cardiac troponin assays: looking bright and moving in the right direction. (2013) (21)
- Differential cardiotoxicity in response to chronic doxorubicin treatment in male spontaneous hypertension-heart failure (SHHF), spontaneously hypertensive (SHR), and Wistar Kyoto (WKY) rats. (2013) (21)
- Biomarkers Enhance Discrimination and Prognosis of Type 2 Myocardial Infarction (2020) (20)
- Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin I concentrations. (2011) (20)
- Post-infarction left ventricular remodeling induces changes in creatine kinase mRNA and protein subunit levels in porcine myocardium. (1997) (20)
- Free oxycodone concentrations in 67 postmortem cases from the Hennepin County medical examiner's office. (2008) (20)
- Men are different than women: it's true for cardiac troponin too. (2014) (19)
- The third Universal Definition of Myocardial Infarction--moving forward. (2012) (19)
- Canine myocardial creatine kinase isoenzyme response to coronary artery occlusion. (1989) (19)
- Cardiac Troponin Testing in Patients with COVID-19: A Strategy for Testing and Reporting Results (2020) (19)
- High-Sensitivity Cardiac Troponin T Improves the Diagnosis of Perioperative MI (2017) (19)
- Assessment of renal function by inulin clearance: comparison with creatinine clearance as determined by enzymatic methods. (1989) (19)
- Preliminary evaluation of the Vitros ECi cardiac troponin I assay. (2000) (19)
- Superiority of postmortem liver fentanyl concentrations over peripheral blood influenced by postmortem interval for determination of fentanyl toxicity. (2013) (19)
- The diagnostic utility of cardiac biomarkers in detecting myocardial infarction. (2005) (19)
- Susceptibility of Cardiac Troponin Assays to Biotin Interference (2019) (19)
- The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity (2016) (18)
- Skeletal muscle creatine kinase MB alterations in women marathon runners (2004) (18)
- Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction (2021) (18)
- Early kinetic profiles of troponin I and T measured by high-sensitivity assays in patients with myocardial infarction. (2020) (18)
- High-Sensitivity Cardiac Troponin Assays: What Analytical and Clinical Issues Need to Be Addressed before Introduction into Clinical Practice? (2010) (18)
- The IFCC Clinical Application of Cardiac Biomarkers Committee's Appraisal of the 2020 ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-segment Elevation: Getting Cardiac Troponin Right. (2020) (18)
- Clinical Features and Outcomes of Emergency Department Patients With High-Sensitivity Cardiac Troponin I Concentrations Within Sex-Specific Reference Intervals. (2019) (17)
- Cocaine-associated fetal death in utero. (1990) (17)
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- proadrenomedullin predicts mortality and major adverse cardiac events in patients presenting with chest pain : Results from the CHOPIN trial Permalink (2015) (0)
- What is the IMA assay really saying? (2005) (0)
- Abstract 19668: Resource Utilization in the Era of Contemporary Sensitive Cardiac Troponin Assays: Comparisons Among Type 1 Myocardial Infarction, Type 2 Myocardial Infarction, Non-Myocardial Infarction Troponin Increases, and Patients with Negative Troponin (2014) (0)
- Predictive Value of NT-proBNP in Patients with Acute Myocardial Infarction (2017) (0)
- A 45‐Year‐Old Man with Substantial Chest Pain (2006) (0)
- Basics of Cardiac Troponin: Practical Aspects of Assays, Potential Analytical Confounders, and Clinical Interpretation (2008) (0)
- CARDIAC TROPONIN-T AND DIAGNOSTIC TEST EVALUATION. AUTHORS' REPLY (1995) (0)
- Brain Natriuretic Peptide (2002) (0)
- Abstract 3610: Troponin and BNP: Heart Failure's Deadly Duo (2006) (0)
- Clinical and Forensic Studies Involving Thiocyanate and Cocaine (1996) (0)
- Laboratory and clinical practice guides for improved diagnostics and risk assessment outcomes: Let's talk about high-sensitivity cardiac troponin I (2019) (0)
- KINETIC COMPARISON OF HUMAN SKELETAL AND HEART MUSCLE CREATINE KINASE ISOENZYMES (1986) (0)
- ALTERATIONS OF CARDIAC SPECIFIC TROPONIN I AND TROPONIN T IN MYOCARDIUM AND SERUM FOLLOWING ACUTE PROLONGED SWIMMING IN RATS (1998) (0)
- Serum Enzyme Changes During Marathon Training (1984) (0)
- Letter in response to "Use of preoperative cardiac troponin T to identify patients at risk for acute myocardial infraction and long-term mortality after major noncardiac surgery". (2014) (0)
- Comprar Management of Food Allergens | Jesse E. Adams | 9781405167581 | Wiley (2009) (0)
- Comprar Markers in Cardiology | Jesse Adams | 9781405134187 | Blackwell Publishing (2007) (0)
- Abstract 11604: The Relationship of Sudden Death and All-cause Mortality to Baseline Values of High-sensitivity Cardiac Troponin T and I in the EVOLVE Trial (2017) (0)
- DIAGNOSTIC PERFORMANCE OF A HIGH-SENSITIVITY CARDIAC TROPONIN I FOR ACUTE MYOCARDIAL INFARCTION USING SEX-SPECIFIC 99TH PERCENTILES DERIVED FROM THE AMERICAN ASSOCIATION OF CLINICAL CHEMISTRY UNIVERSAL SAMPLE BANK (2018) (0)
- Fetal Death In Utero (1990) (0)
- Clinical Chemistry Question and Answer (1999) (0)
- Correction (2020) (0)
- iomarkers in Acute Cardiac Disease he Present and the Future (2006) (0)
- Challenges Interpreting Cardiac Troponin Values (2009) (0)
- EFFECTS OF HINDLIMB SUSPENSION, VITAMIN E SUPPLEMENTATION, AND EXERCISE ON RAT HEART ANTIOXIDANT ENZYMES 373 (1996) (0)
- CAN A SECOND MEASUREMENT OF COPEPTIN IMPROVE ACUTE MYOCARDIAL INFARCTION RULE OUT (2014) (0)
- Abstract 18942: High Sensitivity Cardiac Troponin I Changes Within The Normal Range Do Not Predict Adverse Events In Patients Presenting With Suspected Myocardial Ischemia (2017) (0)
- Abstract 18580: High Sensitivity Cardiac Troponin Sex Specific 99th Percentiles Derived From Universal Sample Bank (2017) (0)
- MUSCLE CREATINE KINASE ISOENZYME ALTERATIONS IN WOMEN MARATHON RUNNERS (1985) (0)
- 44 Rapid Rule-Out of Type 1 Acute Myocardial Infarction Using a Contemporary Cardiac Troponin I Assay with Initial Undetectable Concentrations or Serial Concentrations Below the 99th Percentile (2016) (0)
- The origin and future of cardiac troponin testing. (2022) (0)
- Does Copeptin Provide Additional Risk Stratification in Chest Pain Patients With a Mild Troponin Elevation (2014) (0)
- Troponin Basics for Clinicians (2016) (0)
- CREATINE KINASE M AND B SUBUNIT mRNAs AND ISOENZYME ACTIVITY IN EXERCISE TRAINED RAT SKELETAL MUSCLE: 5 (1980) (0)
- MID-REGIONAL PROADRENOMEDULLIN PREDICTS LONG-TERM MORTALITY IN PATIENTS WITH CHEST PAIN (2014) (0)
- The Need to Develop Clinical Guidance for the Use of High-Sensitivity Cardiac Troponin in Pediatric and Neonatal Patients. (2022) (0)
- Ideal one-hour delta high-sensitivity troponin cutoffs for myocardial infarction in patients with renal dysfunction (2019) (0)
- Abstract 1792: Multiple Biomarker Utilization for Detection of Myocardial Infarction Based on Presentation Sample in Patients with Symptoms Suggestive of Acute Coronary Syndrome (2007) (0)
- Cardiac Biomarkers: Detection of in‐Hospital Myocardial Reinfarction (2008) (0)
- 24 Influence of Renal Dysfunction on High-Sensitivity Cardiac Troponin I for Diagnostic Accuracy of Myocardial Infarction and Outcomes Assessment (2018) (0)
- HIGH SENSITIVITY TROPONIN VALUES RAPIDLY RULE-OUT MYOCARDIAL INFARCTION AND ALLOW FOR ED DISCHARGE IN A HIGHER RISK PATIENT POPULATION COMPARED TO CONTEMPORARY PRACTICE (2020) (0)
- Creatine Kinase lsoenzymeMM Variantsin SkeletalMuscleand Plasma from MarathonRunners (1986) (0)
- Abstract 18879: Discordance between ICD-9 Coded Myocardial Infarction and Adjudicated Diagnosis According to the Universal Definition of Myocardial Infarction (2016) (0)
- Clinical chemistry. (1991) (0)
- Disease Markers Cardiac Biomarkers (2015) (0)
- Analysesof CreatineKinaselsoenzymes and Isoforms in Serumto DetectReperfusion after AcuteMyocardial Infarction1 (1987) (0)
- Beta-hydroxybutyrate assay does not cross-react with gamma-hydroxybutyrate. (2002) (0)
- 386 Cardiac Testing of Patients Ruled Out for Acute Myocardial Infarction Using a Rapid High Sensitivity Troponin I Algorithm, but Not Discharged (2020) (0)
- Advanced CKD, Delta Troponins, Mortality: A Step Toward a Customized Approach During a Perilous Transition? (2022) (0)
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