Fred Winston
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Fred Winstonbiology Degrees
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Biology
Fred Winston's Degrees
- PhD Molecular Biology University of California, Berkeley
- Masters Biochemistry Stanford University
Why Is Fred Winston Influential?
(Suggest an Edit or Addition)Fred Winston's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. (1987) (2466)
- Methods in Yeast Genetics: A Laboratory Course Manual (1990) (1592)
- Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. (1997) (1100)
- Construction of a set of convenient saccharomyces cerevisiae strains that are isogenic to S288C (1995) (959)
- DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. (1998) (727)
- Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. (2001) (654)
- Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene (2004) (604)
- Transcription Elongation Factors Repress Transcription Initiation from Cryptic Sites (2003) (603)
- Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. (1992) (585)
- Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure. (1992) (544)
- Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. (1998) (487)
- Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae. (2000) (423)
- The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. (1992) (384)
- The Swi/Snf family nucleosome-remodeling complexes and transcriptional control. (2000) (381)
- Recent advances in understanding chromatin remodeling by Swi/Snf complexes. (2003) (379)
- Redundant roles for the TFIID and SAGA complexes in global transcription (2000) (379)
- Evidence That Spt6p Controls Chromatin Structure by a Direct Interaction with Histones (1996) (369)
- Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction (1999) (354)
- Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae. (1984) (337)
- The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4. (2001) (310)
- Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes. (1997) (295)
- Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome (2008) (291)
- The bromodomain: a chromatin-targeting module? (1999) (282)
- A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. (2004) (280)
- Changes in histone gene dosage alter transcription in yeast. (1988) (264)
- Chromatin and Transcription in Yeast (2012) (257)
- Regulation of an intergenic transcript controls adjacent gene transcription in Saccharomyces cerevisiae. (2005) (241)
- Eviction and transplacement of mutant genes in yeast. (1983) (241)
- Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster. (2000) (240)
- Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. (1999) (226)
- The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo. (1999) (220)
- Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. (1998) (219)
- SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. (1992) (215)
- Evidence that Set1, a Factor Required for Methylation of Histone H3, Regulates rDNA Silencing in S. cerevisiae by a Sir2-Independent Mechanism (2002) (215)
- SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo (1989) (206)
- SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae. (1992) (195)
- The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiae (1984) (179)
- Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator. (1999) (170)
- Molecular architecture of the S. cerevisiae SAGA complex. (2004) (170)
- SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat (1991) (168)
- Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae. (1991) (165)
- Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. (1991) (162)
- Characterization of amber and ochre suppressors in Salmonella typhimurium (1979) (154)
- Mutations that suppress the deletion of an upstream activating sequence in yeast: involvement of a protein kinase and histone H3 in repressing transcription in vivo. (1993) (150)
- Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor (2007) (139)
- Analysis of Spt7 Function in the Saccharomyces cerevisiae SAGA Coactivator Complex (2002) (134)
- Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae (1990) (132)
- Ty-mediated gene expression of the LYS2 and HIS4 genes of Saccharomyces cerevisiae is controlled by the same SPT genes. (1984) (127)
- A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo (1995) (125)
- The SPT6 gene is essential for growth and is required for delta-mediated transcription in Saccharomyces cerevisiae (1987) (123)
- Evidence that Swi/Snf directly represses transcription in S. cerevisiae. (2002) (121)
- SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiae (1996) (119)
- Evidence that Spt3 functionally interacts with Mot1, TFIIA, and TATA-binding protein to confer promoter-specific transcriptional control in Saccharomyces cerevisiae (1997) (118)
- Isolation and analysis of a novel class of suppressor of Ty insertion mutations in Saccharomyces cerevisiae. (1988) (116)
- Analysis of Transcriptional Activation at a Distance in Saccharomyces cerevisiae (2007) (114)
- Interaction between Transcription Elongation Factors and mRNA 3′-End Formation at the Saccharomyces cerevisiae GAL10-GAL7 Locus* (2005) (110)
- Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast (2008) (108)
- The nucleosome remodeling complex, Snf/Swi, is required for the maintenance of transcription in vivo and is partially redundant with the histone acetyltransferase, Gcn5 (1999) (108)
- The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription (1989) (102)
- Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe. (1990) (102)
- Three genes are required for trans-activation of Ty transcription in yeast. (1987) (98)
- The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo. (1995) (97)
- TBP mutants defective in activated transcription in vivo. (1995) (94)
- The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. (2008) (93)
- The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae. (1991) (93)
- Evidence that Spt2/Sin1, an HMG-Like Factor, Plays Roles in Transcription Elongation, Chromatin Structure, and Genome Stability in Saccharomyces cerevisiae (2006) (93)
- Spt6 Regulates Intragenic and Antisense Transcription, Nucleosome Positioning, and Histone Modifications Genome-Wide in Fission Yeast (2013) (92)
- The Saccharomyces cerevisiae SPT8 gene encodes a very acidic protein that is functionally related to SPT3 and TATA-binding protein. (1994) (89)
- 47 Analysis of SPT Genes: A Genetic Approach toward Analysis of TFIID, Histones, and Other Transcription Factors of Yeast (1992) (88)
- Control of Chromatin Structure by Spt6: Different Consequences in Coding and Regulatory Regions (2010) (83)
- The Saccharomyces cerevisiae Srb8-Srb11 Complex Functions with the SAGA Complex during Gal4-Activated Transcription (2005) (82)
- A transcriptionally regulated expression vector for the fission yeast Schizosaccharomyces pombe. (1989) (82)
- SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae (1994) (82)
- Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation. (2017) (79)
- SPT6, an essential gene that affects transcription in Saccharomyces cerevisiae, encodes a nuclear protein with an extremely acidic amino terminus (1990) (78)
- Amplification of histone genes by circular chromosome formation in Saccharomyces cerevisiae (2006) (77)
- NRG1 is required for glucose repression of the SUC2 and GAL genes of Saccharomyces cerevisiae (2001) (76)
- Evidence that Snf-Swi controls chromatin structure over both the TATA and UAS regions of the SUC2 promoter in Saccharomyces cerevisiae. (1997) (75)
- Histone H2A is required for normal centromere function in Saccharomyces cerevisiae (2000) (72)
- Spn1 Regulates the Recruitment of Spt6 and the Swi/Snf Complex during Transcriptional Activation by RNA Polymerase II (2007) (71)
- Genetic evidence for promoter competition in Saccharomyces cerevisiae (1988) (70)
- Conserved Regulators of Nucleolar Size Revealed by Global Phenotypic Analyses (2013) (69)
- Tra1 has specific regulatory roles, rather than global functions, within the SAGA co‐activator complex (2011) (67)
- Identification and Characterization of Elf1, a Conserved Transcription Elongation Factor in Saccharomyces cerevisiae (2005) (67)
- Identification of a Ty insertion within the coding sequence of the S. cerevisiae URA3 gene (2004) (66)
- Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II* (2010) (64)
- Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae (2002) (63)
- The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response in Saccharomyces cerevisiae (2011) (62)
- Evidence that the Elongation Factor TFIIS Plays a Role in Transcription Initiation at GAL1 in Saccharomyces cerevisiae (2005) (62)
- The SAGA of Spt proteins and transcriptional analysis in yeast: past, present, and future. (1998) (60)
- The Swi/Snf Chromatin Remodeling Complex Is Required for Ribosomal DNA and Telomeric Silencing in Saccharomyces cerevisiae (2004) (59)
- EMS and UV Mutagenesis in Yeast (2008) (57)
- The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26 (2010) (56)
- Spt3 plays opposite roles in filamentous growth in Saccharomyces cerevisiae and Candida albicans and is required for C. albicans virulence. (2002) (55)
- Ty1 transposition in Saccharomyces cerevisiae is nonrandom. (1989) (55)
- The products of the SPT10 and SPT21 genes of Saccharomyces cerevisiae increase the amplitude of transcriptional regulation at a large number of unlinked loci. (1991) (54)
- Nucleosomes and transcription: recent lessons from genetics. (1997) (52)
- Evidence that the Localization of the Elongation Factor Spt16 Across Transcribed Genes Is Dependent Upon Histone H3 Integrity in Saccharomyces cerevisiae (2007) (51)
- Analysis of a Mutant Histone H3 That Perturbs the Association of Swi/Snf with Chromatin (2004) (50)
- The role of FACT in managing chromatin: disruption, assembly, or repair? (2020) (50)
- Characterization of New Spt3 and TATA-Binding Protein Mutants of Saccharomyces cerevisiae: Spt3–TBP Allele-Specific Interactions and Bypass of Spt8 (2007) (47)
- Affinity chromatography of mammalian and yeast nucleosomes. Two modes of binding of transcriptionally active mammalian nucleosomes to organomercurial-agarose columns, and contrasting behavior of the active nucleosomes of yeast. (1990) (46)
- A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for trausforma- (1987) (45)
- The SPT10 and SPT21 genes of Saccharomyces cerevisiae. (1994) (44)
- Specific components of the SAGA complex are required for Gcn4- and Gcr1-mediated activation of the his4-912delta promoter in Saccharomyces cerevisiae. (1999) (43)
- Biochemical and genetic characterization of a yeast TFIID mutant that alters transcription in vivo and DNA binding in vitro (1992) (41)
- Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe (2011) (41)
- Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae (1996) (41)
- Spt6 is required for the fidelity of promoter selection (2018) (40)
- SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat (1991) (39)
- Control of eukaryotic transcription elongation (2001) (39)
- Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae (1993) (39)
- Spt10-Dependent Transcriptional Activation in Saccharomyces cerevisiae Requires both the Spt10 Acetyltransferase Domain and Spt21 (2004) (37)
- Analysis of the yeast SPT3 gene and identification of its product, a positive regulator of Ty transcription. (1986) (34)
- SPT3 is required for normal levels of a-factor and alpha-factor expression in Saccharomyces cerevisiae (1988) (32)
- Growth and Manipulation of Yeast (1992) (30)
- Equivalent mutations in the two repeats of yeast TATA-binding protein confer distinct TATA recognition specificities (1994) (30)
- A Screen for Germination Mutants in Saccharomyces cerevisiae (2011) (30)
- Evidence That Spt10 and Spt21 of Saccharomyces cerevisiae Play Distinct Roles in Vivo and Functionally Interact With MCB-Binding Factor, SCB-Binding Factor and Snf1 (2005) (27)
- Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor spt3 (SUPT3H). (1998) (26)
- Identification and Analysis of Mot3, a Zinc Finger Protein That Binds to the Retrotransposon Ty Long Terminal Repeat (δ) in Saccharomyces cerevisiae (1998) (25)
- A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation (2018) (24)
- Alterations in DNA Replication and Histone Levels Promote Histone Gene Amplification in Saccharomyces cerevisiae (2010) (20)
- Tra 1 has specific regulatory roles , rather than global functions , within the SAGA coactivator complex (2011) (16)
- Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae (2010) (16)
- Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae (2015) (16)
- Identification and analysis of Mot3, a zinc finger protein that binds to the retrotransposon Ty long terminal repeat (delta) in Saccharomyces cerevisiae. (1998) (14)
- The biochemical and genetic discovery of the SAGA complex. (2020) (14)
- A mutant tRNA affects delta-mediated transcription in Saccharomyces cerevisiae. (1992) (14)
- Essential histone chaperones collaborate to regulate transcription and chromatin integrity (2020) (13)
- Spt 6 Is Required for Heterochromatic Silencing in the Fission Yeast (2011) (13)
- Control of lysogenization by phage P22. I. The P22 cro gene. (1981) (11)
- The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae (2020) (11)
- NRG 1 is required for glucose repression of the SUC 2 and GAL genes of Saccharomyces cerevisiae (2001) (10)
- Whole‐Genome Sequencing of Yeast Cells (2019) (10)
- The structure of an Iws 1 / Spt 6 complex reveals an interaction domain conserved in TFIIS , Elongin A and Med 26 Marie - (2010) (10)
- Control of lysogenization by phage P22. II. Mutations (clyA) in the cl gene that cause increased lysogenization. (1981) (9)
- Identification and analysis of homologues of Saccharomyces cerevisiae Spt3 suggest conserved functional domains (1998) (8)
- Auxin‐Inducible Degron System for Depletion of Proteins in Saccharomyces cerevisiae (2019) (8)
- An Unexpected Role for Ubiquitylation of a Transcriptional Activator (2005) (8)
- Back to the Future: Mutant Hunts Are Still the Way To Go (2016) (7)
- Evidence That Spt 10 and Spt 21 of Saccharomyces cerevisiae Play Distinct Roles in Vivo and Functionally Interact With MCB-Binding Factor , SCB-Binding Factor and Snf 1 (2005) (5)
- The Schizosaccharomyces pombe inv1+ Regulatory Region Is Unusually Large and Contains Redundant cis-Acting Elements That Function in a SAGA- and Swi/Snf-Dependent Fashion (2012) (4)
- Cell-Cycle Perturbations Suppress the Slow-Growth Defect of spt10Δ Mutants in Saccharomyces cerevisiae (2013) (4)
- Saccharomyces cerevisiae in ) δ Retrotransposon Ty Long Terminal Repeat ( Finger Protein That Binds to the Identification and Analysis of Mot 3 , a Zinc (1998) (4)
- Erratum: SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat (Molecular and Cellular Biology 11 (3016)) (1991) (3)
- Specific Components of the SAGA Complex Are Required for Gcn 4-and Gcr 1-Mediated Activation of the his 4-912 d Promoter in Saccharomyces cerevisiae Aimée (1999) (3)
- Mutagenesis of Yeast Cells (1990) (3)
- Presenting Genetics: Honoring the Past, Embracing the Future (2009) (2)
- Mutations inSPT161CDC68 Suppress cis- andtrans-Acting Mutations ThatAffect Promoter Function inSaccharomyces cerevisiae (1991) (2)
- Mutations in SPT161CDC68 Suppress cis- and trans-Acting Mutations That Affect Promoter Function in Saccharomyces cerevisiae (2)
- A transcription switch toggled by noncoding RNAs (2009) (2)
- F Saccharomyces cerevisiae . human homolog of the SPT 4 gene of Identification and analysis of a functional (1996) (1)
- The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions (2021) (1)
- Identification and Analysis of a Functional Human Homolog of the SPT 4 Gene of Saccharomyces cerevisiae (1996) (1)
- SPT 1 O and SPT 21 Are Required for Transcription of Particular Histone Genes in Saccharomyces cerevisiae (1)
- SPT1OandSPT21AreRequired forTranscription ofParticular Histone GenesinSaccharomyces cerevisiae (1994) (0)
- The conserved histone chaperone Spt6 facilitates DNA replication and mediates genome instability (2022) (0)
- Winston at a post-activator-binding step (1999) (0)
- Lys Thr Gin Lys Phe Tyr Lys Arg Leu Gln Glu Val Lou His Lys Lys Gin Ile Val 837 EoBI 2512 GAC AGT AGA GGA CAT ACT ATT CCA ATC ATT TAC GTT GAG GAC GAA GTC GCT ATC (0)
- Saccharomyces cerevisiaetranscription in Regulation of an intergenic transcript controls adjacent gene data (2005) (0)
- Biochemical andGenetic Characterization ofa YeastTFIIDMutant ThatAlters Transcription InVivoandDNA Binding InVitro (1992) (0)
- Fred Winston cerevisiae Saccharomyces and Telomeric Silencing in Complex Is Required for Ribosomal DNA The Swi / Snf Chromatin Remodeling (2004) (0)
- The SPTlO and SPT 21 Genes of Saccharomyces cerevisiae (2002) (0)
- pombe fbp1 gene occurs by a cAMP signaling pathway. Glucose repression of transcription of the Schizosaccharomyces (2007) (0)
- TheSaccharomyces cerevisiae SPT131GALJJ GeneHasBoth Positive andNegative Regulatory RolesinTranscription (1989) (0)
- Analyses Conserved Regulators of Nucleolar Size Revealed by Global Phenotypic ` (2013) (0)
- Suppressor mutations that make the essential transcription factor Spn1/Iws1 dispensable in Saccharomyces cerevisiae (2022) (0)
- Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae (1991) (0)
- Fission Yeast and Histone Modifications Genome-Wide in Transcription , Nucleosome Positioning , Spt 6 Regulates Intragenic and Antisense (2013) (0)
- Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharom yces cerevisiae (2008) (0)
- Supplemental Information Spt 5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation (2017) (0)
- SP 7 Y 5 , the Gene Encoding the Yeast TATA B inding Factor TFIID , Is Required for Normal Transcription Initiation In V ivo (2003) (0)
- The conserved histone chaperone Spt6 is strongly required for DNA replication and genome stability. (2023) (0)
- The 2009 Genetics Society of America Medal (2009) (0)
- Colocalization of Spt5 and Spt6 with Pol IIo (Pol IIo phosphorylated on Ser2) on polytene chromosomes (2011) (0)
- vivo and DNA binding in vitro. yeast TFIID mutant that alters transcription in Biochemical and genetic characterization of a (2013) (0)
- Past, Present, and Future The SAGA of Spt Proteins and Transcriptional Analysis in Yeast: (2012) (0)
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