Freddy Radtke
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Computer Science
Why Is Freddy Radtke Influential?
(Suggest an Edit or Addition)Freddy Radtke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Deficient T cell fate specification in mice with an induced inactivation of Notch1. (1999) (1523)
- Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells (2005) (1331)
- Notch1 functions as a tumor suppressor in mouse skin (2003) (1020)
- VEGF is required for growth and survival in neonatal mice. (1999) (930)
- Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation (2001) (904)
- The role of Notch in tumorigenesis: oncogene or tumour suppressor? (2003) (855)
- Self-Renewal and Cancer of the Gut: Two Sides of a Coin (2005) (750)
- Notch regulation of lymphocyte development and function (2004) (597)
- Transcription factor RORα is critical for nuocyte development (2012) (515)
- Notch signaling in the immune system. (2010) (499)
- The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression. (1994) (477)
- Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus (2001) (448)
- Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment (2008) (446)
- Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. (2007) (432)
- Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2 (2008) (406)
- β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis (2004) (391)
- Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. (2011) (373)
- Cloned transcription factor MTF‐1 activates the mouse metallothionein I promoter. (1993) (367)
- Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. (2002) (363)
- Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. (2005) (355)
- Regulation of innate and adaptive immunity by Notch (2013) (355)
- Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling (2012) (345)
- Tumor vessel normalization by chloroquine independent of autophagy. (2014) (336)
- Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity (2009) (314)
- Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. (2005) (299)
- Notch1 Is Required for Maintenance of the Reservoir of Adult Hippocampal Stem Cells (2010) (287)
- Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development (2001) (270)
- Mechanisms of T cell development and transformation. (2011) (269)
- Signalling strength determines proapoptotic functions of STING (2017) (268)
- Essential Role of Endothelial Notch1 in Angiogenesis (2005) (268)
- Notch1 is required for neuronal and glial differentiation in the cerebellum. (2002) (265)
- Notch as a tumour suppressor (2017) (259)
- Stem cells living with a Notch (2013) (256)
- Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. (2001) (226)
- Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice (2008) (219)
- Multiple functions of Notch signaling in self‐renewing organs and cancer (2006) (218)
- Critical Role of Endothelial Notch1 Signaling in Postnatal Angiogenesis (2007) (207)
- Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex (2008) (202)
- Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome (2010) (201)
- Notch1 control of oligodendrocyte differentiation in the spinal cord (2002) (200)
- Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma (2010) (196)
- Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1. (1994) (196)
- Hedgehog signaling is dispensable for adult hematopoietic stem cell function. (2009) (195)
- Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self‐renewal (2005) (193)
- Notch and cancer: a double-edged sword (2007) (191)
- Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis (2008) (190)
- Fibroblast Growth Factor Receptor Signaling Promotes Radial Glial Identity and Interacts with Notch1 Signaling in Telencephalic Progenitors (2004) (189)
- Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation (2007) (189)
- Notch inhibits osteoblast differentiation and causes osteopenia. (2008) (188)
- Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. (2009) (174)
- Notch and cancer: a double-edged sword (2008) (173)
- Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. (2000) (172)
- Induction of Cardiogenesis in Embryonic Stem Cells via Downregulation of Notch1 Signaling (2006) (159)
- Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin (2010) (157)
- Functional domains of the heavy metal-responsive transcription regulator MTF-1. (1995) (156)
- Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. (2012) (154)
- Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. (2006) (151)
- Notch signaling is required for exocrine regeneration after acute pancreatitis. (2008) (150)
- Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. (2010) (147)
- Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (147)
- The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development (2008) (143)
- Multiple roles of Notch signaling in the regulation of epidermal development. (2008) (141)
- Notch-induced T cell development requires phosphoinositide-dependent kinase 1 (2007) (140)
- Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. (2008) (138)
- Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. (2011) (138)
- Notch1 is essential for postnatal hair follicle development and homeostasis. (2005) (132)
- Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. (2010) (130)
- From gut homeostasis to cancer. (2006) (128)
- Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses (2014) (126)
- Notch signaling in T- and B-cell development. (2004) (125)
- The Notch pathway controls fibrotic and regenerative repair in the adult heart (2012) (125)
- Control of the adaptive response of the heart to stress via the Notch1 receptor pathway (2008) (124)
- Notch1 and Notch2 receptors influence progressive hair graying in a dose‐dependent manner (2007) (123)
- Notch signaling in lymphopoiesis. (2003) (121)
- DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. (2015) (120)
- Analysis of Notch1 Function by In Vitro T Cell Differentiation of Pax5 Mutant Lymphoid Progenitors1 (2004) (117)
- Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction (2015) (116)
- Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. (2007) (114)
- Notch signaling in solid tumors. (2010) (112)
- Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells (2007) (111)
- IRF6 is a mediator of Notch pro‐differentiation and tumour suppressive function in keratinocytes (2011) (111)
- Loss of cutaneous TSLP-dependent immune responses skews the balance of inflammation from tumor protective to tumor promoting. (2012) (109)
- Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice (2005) (108)
- Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. (2012) (107)
- Smooth Muscle Notch1 Mediates Neointimal Formation After Vascular Injury (2009) (106)
- Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53. (2013) (97)
- Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome (2012) (97)
- Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. (2010) (97)
- Derivation of Traceable and Transplantable Photoreceptors from Mouse Embryonic Stem Cells (2014) (94)
- Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch (2015) (92)
- Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse (2012) (92)
- Regulation of monocyte cell fate by blood vessels mediated by Notch signalling (2016) (91)
- Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength (2013) (85)
- Conditional ablation of Notch signaling in pancreatic development (2008) (83)
- Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major (2012) (82)
- Notch1 and T-cell development: insights from conditional knockout mice. (2001) (82)
- Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. (2010) (81)
- Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production (2013) (78)
- Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone. (2018) (77)
- Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies1 (2009) (77)
- The role of Notch signaling during hematopoietic lineage commitment (2002) (76)
- Notch in T-ALL: new players in a complex disease. (2011) (75)
- Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGFβ (2019) (74)
- Notch1 in Bone Marrow–Derived Cells Mediates Cardiac Repair After Myocardial Infarction (2011) (70)
- The Notch ‘gospel’ (2005) (66)
- Cutaneous Notch signaling in health and disease. (2013) (65)
- Notch Signaling Regulates Follicular Helper T Cell Differentiation (2013) (65)
- Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. (2002) (62)
- Rorα is essential for nuocyte development (2011) (60)
- T cell fate specification and alphabeta/gammadelta lineage commitment. (2001) (59)
- Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands (2017) (58)
- Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract (2016) (53)
- Factors determining the spontaneous activation of splenic dendritic cells in culture (2011) (52)
- Cutting Edge: An Essential Role for Notch-1 in the Development of Both Thymus-Independent and -Dependent T Cells in the Gut1 (2000) (52)
- Notch1 expression on T cells is not required for CD4+ T helper differentiation (2004) (51)
- Jagged1 is the major regulator of notch‐dependent cell fate in proximal airways (2013) (51)
- Corneal epithelial stem cells and their niche at a glance (2017) (49)
- Notch signaling in hematopoiesis and lymphopoiesis: Lessons from Drosophila (2005) (49)
- LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance. (2013) (48)
- Identification of Epidermal Pdx1 Expression Discloses Different Roles of Notch1 and Notch2 in Murine KrasG12D-Induced Skin Carcinogenesis In Vivo (2010) (46)
- Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes (2019) (45)
- Additive and global functions of HoxA cluster genes in mesoderm derivatives. (2010) (43)
- Notch1 haploinsufficiency causes ascending aortic aneurysms in mice. (2017) (43)
- Distinct Spatial and Molecular Features of Notch Pathway Assembly in Regulatory T Cells (2012) (42)
- The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. (2007) (40)
- The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool (2017) (40)
- Paradigms of Notch Signaling in Mammals (2005) (37)
- Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud (2005) (37)
- Pharmacological disruption of the Notch transcription factor complex (2020) (35)
- Very High Throughput Electrical Cell Lysis and Extraction of Intracellular Compounds Using 3D Carbon Electrodes in Lab-on-a-Chip Devices (2012) (34)
- Differential sensitivity of zinc finger transcription factors MTF-1, Sp1 and Krox-20 to CpG methylation of their binding sites. (1996) (33)
- RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice (2011) (33)
- Stem cell biology meets systems biology (2009) (30)
- AMPK promotes survival of c‐Myc‐positive melanoma cells by suppressing oxidative stress (2018) (29)
- Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression. (2015) (27)
- Role of Jagged1 in Arterial Lesions After Vascular Injury (2011) (25)
- Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance. (2013) (23)
- Phage Selection of Bicyclic Peptide Ligands of the Notch1 Receptor (2015) (23)
- Notch 1 Functions as a Tumor Suppressor in a Model of Kras – Induced Pancreatic Ductal Adenocarcinoma (2010) (22)
- Inhibition of Fibroblast Growth by Notch1 Signaling Is Mediated by Induction of Wnt11-Dependent WISP-1 (2012) (21)
- Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner (2016) (21)
- Smooth Muscle Notch 1 Mediates Neointimal Formation After Vascular Injury (2009) (19)
- Notch1—WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis (2016) (18)
- Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development (2020) (18)
- Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. (2020) (17)
- Transcriptional Regulation by Heavy Metals, Exemplified at the Metallothionein Genes (1995) (17)
- Transgenic expression of Notch in melanocytes demonstrates RBP‐Jκ‐dependent signaling (2010) (14)
- Haematopoietic stem cell niche in Drosophila. (2007) (14)
- Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion (2015) (14)
- Notch 1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (12)
- The E protein-TCF1 axis controls γδ T cell development and effector fate (2021) (12)
- Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses. (2010) (12)
- GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells (2020) (11)
- Chromosomal number aberrations and transformation in adult mouse retinal stem cells in vitro. (2009) (11)
- Specific Notch receptor–ligand interactions control human TCR-ab/gd development by inducing differential Notch signal strength (2013) (9)
- Notch Regulation of the Immune System (2012) (8)
- Generation and characterization of a Notch1 signaling‐specific reporter mouse line (2012) (8)
- DL4‐mediated Notch signaling is required for the development of fetal αβ and γδ T cells (2013) (8)
- Chromosomal number aberrations and transformation in adult mouse retinal stem cells in vitro (2009) (7)
- Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation (2014) (6)
- LRF Regulates Self-Renewal of Hematopoietic Stem Cells by Blocking Notch1-Mediated T Cell Differentiation (2008) (6)
- Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL (2022) (6)
- Notch Signaling Promotes Disease Initiation and Progression in Murine Chronic Lymphocytic Leukemia. (2020) (6)
- A third Notch in colorectal cancer progression and metastasis (2020) (6)
- cell self-renewal and differentiation Jagged1 dependent Notch signaling is dispensable for hematopoietic stem (2013) (5)
- PHARMACOLOGICAL ACTIVITY OF CB‐103 IN HAEMATOLOGICAL MALIGNANCIES – AN ORAL PAN‐NOTCH INHIBITOR WITH A NOVEL MODE OF ACTION (2017) (4)
- Pharmacological Activity Of Cb-103-An Oral Pan-Notch Inhibitor With A Novel Mode Of Action (2017) (4)
- Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice (2016) (4)
- Corneal epithelial stem cells and their niche at a glance (2017) (3)
- Abstract B061: Targeting lymphomas with the novel first-in-class pan-NOTCH transcription inhibitor CB-103 (2018) (3)
- Regulation of metallothionein gene expression in Cd- or Zn-adapted RK-13 cells (1995) (3)
- A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation (2022) (3)
- Dual Function of Notch Signaling in Cancer: Oncogene and Tumor Suppressor (2018) (3)
- 66PPharmacological activity of CB-103: An oral pan-NOTCH inhibitor targeting the NOTCH transcription complex (2018) (3)
- Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells (2016) (2)
- The Notch ‘ gospel ’ Workshop on Notch Signalling in Development and Cancer (2005) (2)
- Linking inflammation and mechanotransduction in stem cell regulation (2016) (2)
- The Two Faces of Notch in Solid Cancers (2017) (2)
- Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease (2014) (2)
- Generation of a Gal4-dependent gene recombination and illuminating mouse (2022) (1)
- Endothelial Notch 1 Is Required for Proper Development of the Semilunar Valves and Cardiac Out fl ow Tract (2016) (1)
- P4-352 Effects of a gamma-secretase inhibitor on hematopoietic cell lineages (2004) (1)
- Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation (2013) (1)
- LRF Is Indispensable for Hematopoietic Stem Cell Function Via Blocking Notch1-Mediated T Cell-Instructive Signals in the Bone Marrow Niche. (2009) (1)
- Epidermal gd T cells sense precancerous cellular dysregulation and initiate immune responses (2010) (1)
- Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model (2021) (1)
- Notch Signaling In Normal And Malignant T-Cells (2012) (1)
- Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool. (2010) (1)
- Role of myc in melanoma (2011) (1)
- Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells (2022) (1)
- Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease (2018) (0)
- PS978 DISCOVERY OF NOVEL C/D BOX SNORNAS THAT ARE REQUIRED FOR LEUKEMIA CELL PROLIFERATION (2019) (0)
- Develop Independently of the T cell Lineage (2013) (0)
- T Cell Differentiation Notch Signaling Regulates Follicular Helper (2013) (0)
- In vitro anti‐lymphoma activity of the first‐in‐class pan‐NOTCH transcription inhibitor CB‐103 (2022) (0)
- Increased Chromosomal Aberrations and Transformation of Adult Mouse Retinal Stem Cells (2008) (0)
- Abstract LB-034: Tcf7: an essential mediator in Notch-induced T-ALL (2016) (0)
- Abstract 338: A novel small molecule inhibitor of the Notch transcription activation complex (2016) (0)
- Notch1 signaling is limited in healthy mature kidneys in vivo (2023) (0)
- Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis (2022) (0)
- Notch signaling pathway in tooth shape variations (2022) (0)
- recognition and its disorders (2009) (0)
- Abstract 1163: Non clinical pharmacology, pharmacokinetics and safety profiling of CB-103: A novel first-in-class small molecule inhibitor of the NOTCH pathway (2017) (0)
- Conditional ablation of Notch 1 from the vertebrate central nervous system (2008) (0)
- Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling (2017) (0)
- Left Anterior Coronary Artery Ligation / Myocardial Infarction Model (2011) (0)
- Decision letter: IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation (2020) (0)
- Abstract 3434: The Role Of Notch Signaling In The Adult Myocardium: Control Of Myocyte Hypertrophy And Differentiation (2008) (0)
- Abstract 5167: Notch1 is required for endothelial cell lineage differentiation from adult bone marrow stem cellsin vitro (2010) (0)
- Abstract IA10: Notch signaling and cancer (2016) (0)
- Regenerative Behavior Macroenvironmental Regulation of Hair Cycling and Collective Subject Collection The Skin and Its Diseases Lineage Analysis of Epidermal Stem Cells (2013) (0)
- Abstract 4085: Notch1 signaling determines melanoma-regulating role of tumor stromal fibroblasts (2016) (0)
- Activated Notch1 signalling has repressive effects on wound healing in diabetes (2013) (0)
- Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia (2023) (0)
- Role of Notch1 and Notch2 receptors in CD4+ T helper differentiation (2008) (0)
- Notch signaling is dispensable for mature melanocytes but essential for melanocyte stem cells (2011) (0)
- This information is current as Tissue-Restricted Innate-like T Cells Notch Signaling Regulates the Homeostasis of (2016) (0)
- Wound healing rate is impaired by a glucose-induced overactive Delta4-Notch1 loop (2014) (0)
- 858 Deficiency of Notch2 suppresses pancreatic carcinogenesis and Myc signaling in vivo (2010) (0)
- Qualitative Crosstalk Analysis of Wnt and Notch Signaling in Mammalian Skin (2007) (0)
- Abstract 5799: Characterization and profiling of CB-103, a novel small-molecule protein-protein interaction inhibitor targeting the NOTCH transcription complex (2018) (0)
- LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation (2011) (0)
- Development Of A Novel First-In-Class Oral Inhibitor Of The Notch Pathway (2016) (0)
- Table of Contents (1993) (0)
- Mouse CD11c B220 Gr1 (cid:1) plasmacytoid dendritic cells develop independently of the T-cell lineage (2002) (0)
- Notch Signaling Pathway in Tooth Shape Variations throughout Evolution (2023) (0)
- Canonical NOTCH signaling controls the early progenitor state and emergence of the medullary epithelial lineage in fetal thymus development (2019) (0)
- lymphopoiesis -catenin does not perturb hematopoiesis or γ - and β Simultaneous loss of (2013) (0)
- hematopoietic stem cell maintenance LRF-mediated Dll4 repression in erythroblasts is necessary for (2013) (0)
- Notch1 and Notch2 signaling through RBP-J kappa is essential for proper hair pigmentation and RPE development in the mouse (2008) (0)
- Abstract 2695: Direct targeting of NOTCH transcription complex by a novel small molecule CB-103 circumvents dose-limiting toxicities associated with pan-NOTCH inhibitors (2019) (0)
- Signalling strength determines proapoptotic functions of STING (2017) (0)
- Novel Monoclonal Antibodies Development and Activation Revealed by Surface Expression during T Cell Dynamic Regulation of Notch 1 and Notch 2 (2009) (0)
- Abstract 11619: Control of Cardiac Hypertrophy and Fibrosis by the Notch Pathway (2011) (0)
- Thetranscription factor MTF-1isessential forbasal and heavymetal-induced metallothionein geneexpression (1994) (0)
- We employed two independent approaches to inactivate the angiogenic protein VEGF in newborn mice: inducible, Cre- loxP- mediated gene targeting, or administration of mFlt(1- 3)-IgG, a soluble VEGF receptor chimeric protein. Partial inhibition of VEGF achieved by inducible gene targeting (1999) (0)
- Mutant Pax5 Cell Differentiation of Analysis of Notch1 Function by In Vitro T (0)
- Pancreas-specific ablation of Notch2 but not Notch1 compromises KrasG12D-induced PanIN progression and tumor development (2008) (0)
- From the cradle to the work place: pleitropic roles of Notch in immunity. (Preface). (2012) (0)
- BCL6 and BCoR gang up on Notch to regulate left-right patterning. (2010) (0)
- relevance to chemoresistance derived cells in mice: - Notch1 regulates angio-supportive bone marrow (2013) (0)
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