Frederic L. Holmes
American historian
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(Suggest an Edit or Addition)According to Wikipedia, Frederic Lawrence Holmes was an American historian of science, specifically for chemistry, medicine and biology. Holmes earned his bachelor's degree in biology from Massachusetts Institute of Technology in 1954 and then began graduate study in the history department of Harvard University, where he graduated with MA in 1958. His graduate study was interrupted by two years of service in the United States Air Force and when he returned to Harvard he transferred to the department of the history of science, graduating with PhD in 1962 with thesis Claude Bernard and the concept of internal environment. For his dissertation, he reconstructed Claude Bernard's path of discovery of basic physiological functions, such as those of the liver, on the basis of Bernard's laboratory books from the 1840s. Mirko Grmek referred the laboratory books to Holmes. He then spent two years at MIT as a postdoc. At Yale University he became in 1964 an assistant professor and in 1968 an associate professor of the history of science. In 1972 he became a professor at the University of Western Ontario and head of his department. In 1979 he returned to Yale as a full professor and chair from 1979 to 2002 of the Section of the History of Medicine in the Yale School of Medicine.
Frederic L. Holmes's Published Works
Published Works
- Claude Bernard and Animal Chemistry: The Emergence of a Scientist (1974) (103)
- The old martyr of science: The frog in experimental physiology (1993) (77)
- Lavoisier and the Chemistry of Life: An Exploration of Scientific Creativity (1987) (71)
- Meselson, Stahl, and the Replication of DNA: A History of 'The Most Beautiful Experiment in Biology' (2001) (68)
- Scientific Writing and Scientific Discovery (1987) (62)
- Investigative Pathways: Patterns and Stages in the Careers of Experimental Scientists (2004) (59)
- The Complementarity of Teaching and Research in Liebig's Laboratory (1989) (58)
- The Investigative Enterprise: Experimental Physiology in Nineteenth-Century Medicine (1992) (56)
- Reworking the bench : research notebooks in the history of science (2003) (55)
- Elementary Analysis and the Origins of Physiological Chemistry (1963) (54)
- Eighteenth-Century Chemistry as an Investigative Enterprise (1991) (54)
- The Fine Structure of Scientific Creativity (1981) (42)
- Reworking the Bench (2003) (39)
- Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics (2006) (35)
- Instruments and experimentation in the history of chemistry (2000) (33)
- The "Revolution in Chemistry and Physics": Overthrow of a Reigning Paradigm or Competition between Contemporary Research Programs? (2000) (32)
- 6. Argument and Narrative in Scientific Writing (1991) (29)
- The longue durée in the history of science. (2003) (28)
- Claude Bernard, the milieu intérieur, and regulatory physiology. (1986) (28)
- Research schools : historical reappraisals (1993) (28)
- From Elective Affinities to Chemical Equilibria: Berthollet's Law of Mass Action (1962) (28)
- Hans Krebs and the discovery of the ornithine cycle. (1980) (27)
- Analysis by Fire and Solvent Extractions: The Metamorphosis of a Tradition (1971) (26)
- The formation of a scientific life, 1900-1933 (1991) (25)
- Between Biology and Medicine: The Formation of Intermediary Metabolism (1992) (25)
- A Scientific Autobiography of Joseph Priestley (1733-1804) (1970) (23)
- 5. Manometers, Tissue Slices, and Intermediary Metabolism (1992) (20)
- The Communal Context for Etienne-François Geoffroy's “Table des rapports” (1996) (19)
- Do We Understand Historically How Experimental Knowledge is Acquired? (1992) (16)
- The Lunar Society of Birmingham: A Social History of Provincial Science and Industry in 18th Century England (1965) (14)
- Antoine Lavoisier: The Next Crucial Year: Or, The Sources of His Quantitative Method in Chemistry (1997) (13)
- 2. Experiment, Quantification, and Discovery: Helmholtz's Early Physiological Researches, 1843-50 (1993) (13)
- The Concept of the Gene in Development and Evolution: Seymour Benzer and the Definition of the Gene (2000) (11)
- The boundaries of Lavoisier's chemical revolution/Les limites de la révolution chimique de Lavoisier (1995) (10)
- Dictionary of scientific biography (1990) (9)
- Justus Liebig and the Plant Physiologists (2002) (8)
- Laboratory Notebooks and Investigative Pathways (2003) (7)
- The DNA replication problem, 1953-1958. (1998) (7)
- Chemistry in the Acadéémie Royale des Sciences (2003) (7)
- Intermediary Metabolism in the Early Twentieth Century (1986) (6)
- Lavoisier's Conceptual Passage (1988) (6)
- The intake-output method of quantification in physiology. (1987) (6)
- Joseph Barcroft and the fixity of the internal environment (1969) (5)
- Early Theories of Protein Metabolism (1979) (5)
- The Role of Johannes Müller in the Formation of Helmholtz's Physiological Career (1994) (5)
- Justus Liebig and the Construction of Organic Chemistry (1993) (5)
- Experimental Systems, Investigative Pathways, and the Nature of Discovery (2009) (4)
- Beautiful Experiments in the Life Sciences (1996) (4)
- Lavoisier and Krebs: The Individual Scientist in the Near and Deeper Past (1984) (4)
- The transformation of the science of nutrition (1975) (4)
- ANTOINE LAVOISIER & THE CONSERVATION OF MATTER: Delving deeper than the thumbnail sketches often found in chemistry textbooks into the way this seminal 18th-century French chemist designed and conducted his experiments reveals a scientist very recognizable to practicing chemists today (1994) (4)
- Investigative and pedagogical styles in French chemistry at the end of the 17th century (2004) (3)
- The Sickly Stuarts (2003) (3)
- "Eighteenth-Century Chemistry as an Investigative Enterprise. Five Lectures delivered at the International Summer School in History of Science Bologna, August 1988", Frederic Lawrence Holmes, Berkeley 1989 : [recenzja] / Stefan Zamecki. (1991) (2)
- Overtures to Biology. The speculations of eighteenth-century naturalists. Philip C. Ritterbush. Yale University Press, New Haven, Conn., 1964. x + 287 pp. Illus. $7.50 (1964) (2)
- Research Trails and the Creative Spirit: Can Historical Case Studies Integrate the Short and Long Timescales of Creative Activity? (1996) (2)
- Crystals and Carriers: The Chemical and Physiological Identification of Hemoglobin (1995) (2)
- The Physical Sciences in the Life Sciences (2001) (1)
- Hans Krebs. Volume 1, The Formation of a Scientific Life 1900-1933.@@@Hans Krebs. Volume 2, Architect of Intermediary Metabolism 1933-1937. (1993) (1)
- What Was the Chemical Revolution About ? (2011) (1)
- Dialogue: A Discussion Among Historians of Science and Scientists (1979) (1)
- Thomas Rogers Forbes (1911-1988). Anatomist, medical educator, and historian of medicine. (1989) (1)
- The chemical revolution and the art of healing. (1995) (1)
- Scientific creativity in biomedical research: some case histories. (1996) (1)
- Pondering authorship (1995) (1)
- The Essential Bernard (1975) (0)
- The Responsible Medical Historian1 (1990) (0)
- Twists and Turns (2001) (0)
- The essays in this collection, the product of a conference at the Dibner Institute, explore the role of instruments and the place of experiment in the history of Western chemistry. Editors Frederic Holmes and Trevor Levere (2002) (0)
- Book reviews (2001) (0)
- Book Review:Francis Crick and James Watson: And the Building Blocks of Life Edward Edelson (2001) (0)
- Advancement in Science (1998) (0)
- Mapping the evolution of biochemistry (1982) (0)
- I. Chemists, Physiologists, the Problem of Nutrition (1974) (0)
- Architect of intermediary metabolism, 1933-1937/ Frederic Lawrence Holmes (1993) (0)
- Appendix C (See Chapter II at n. 4) (1974) (0)
- The responsible medical historian. (1990) (0)
- The history of biochemistry: a review of the literature of the field. (1982) (0)
- Claude Bernard, Rationalite d'une methode (1999) (0)
- Creativity and discovery: An introduction to the special issue (1994) (0)
- II. Paris and Giessen at Odds (1974) (0)
- The Subunits of Semiconservative Replication (2001) (0)
- The Unseen Band (2001) (0)
- ABBREVIATIONS USED IN THE BIBLIOGRAPHY AND NOTES (1974) (0)
- One Discovery, Three Stories (2001) (0)
- Meselson and Stahl (2001) (0)
- , 1 the 1970 s and 1980 s witnessed the work of (2011) (0)
- Appendix E (See Chapter V at n. 12) (1974) (0)
- XIII. Herbivorous and Carnivorous Nutrition–a Success amid Further Setbacks (1974) (0)
- Essay Review: Biochemistry and the Historian: Molecules and Life (1975) (0)
- A Short History of Biology. Isaac Asimov (1965) (0)
- Biochemistry and the historian. (1975) (0)
- Crossing Fields: Chemical Bonds to Biological Mutants (2001) (0)
- VII. The Investigation of Digestion, 1750–1830 (1974) (0)
- XVI. The Persistence of Claude Bernard (1974) (0)
- Book Review:The Growth of Medical Thought Lester S. King (1964) (0)
- XIV. Claude Bernard and Louis Mialhe (1974) (0)
- An Extremely Beautiful Experiment (2001) (0)
- Seymour Benzer and the convergence of molecular biology with classical genetics (2004) (0)
- XIX. The Source of Sugar in Animals (1974) (0)
- XI. Bernard and Barreswil in a Busy Field (1974) (0)
- Working at High Speed (2001) (0)
- Images of an Experiment (2001) (0)
- IV. The French Chemists on the Defensive (1974) (0)
- Hans Adolf Krebs 1900–1981: Biochemist Discoverer of the urea cycle and the citric acid cycle (2011) (0)
- Miescher and Successors: A Century of DNA . A History of the Discovery of the Structure and Function of the Genetic Substance. Franklin H. Portugal and Jack S. Cohen. MIT Press, Cambridge, Mass., 1978. xiv, 384 pp., illus. $17.50. (1978) (0)
- A review of François Jacob, The logic of life, a history of heredity. Trans. Betty E. Spillmann. New York. Pantheon Books. 1973. viii, 348 pp. (1977) (0)
- XII. Scientific Imagination Confronted by Experimental Complexity (1974) (0)
- IX. French Investigations of Digestion (1974) (0)
- Award of the Sarton Medal for 1981 (1982) (0)
- History of Biology: Overtures to Biology . The speculations of eighteenth-century naturalists. Philip C. Ritterbush. Yale University Press, New Haven, Conn., 1964. x + 287 pp. Illus. $7.50. (1964) (0)
- VI. Origins of Claude Bernard’s Research in Animal Chemistry (1974) (0)
- Book Notes (1972) (0)
- XV. A New Look at Old Projects (1974) (0)
- The Replication Problem (2001) (0)
- Preface (1993) (0)
- XVIII. The Search for Sugar (1974) (0)
- XVII. The Pancreatic Juice: “A Different Field of Activity” (1974) (0)
- V. The Persistence of Jean-Baptiste Boussingault (1974) (0)
- Appendix A (see Chapter XV, n. 26) (1974) (0)
- III. The Debate over the Source of Animal Fat (1974) (0)
- Spanish Medicine before the Eighteenth Century (1980) (0)
- The Fielding H. Garrison lecture. Patterns of scientific creativity. (1986) (0)
- Book Review:From Chemical Philosophy to Theoretical Chemistry: Dynamics of Matter and Dynamics of Disciplines, 1800-1950 Mary Jo Nye (1995) (0)
- X. Bernard’s First Theory of Gastric Digestion (1974) (0)
- Miescher and successors. (1978) (0)
- VIII. The Pepsin Theory (1974) (0)
- Alluring Wisconsin : the historic glamor and natural loveliness of an American Commonwealth (1937) (0)
- The Big Machine (2001) (0)
- The Scholar’s Seeing Eye (2003) (0)
- Appendix B (See Chapter XV, n. 30) (1974) (0)
- Notes for Contributors (1995) (0)
- Éloge: Dov Ospovat, 14 June 1947-28 September 1980 (1981) (0)
- The Legacy of Mirko Grmek's Historical Studies of Claude Bernard (1999) (0)
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