Frederick A. Valeriote
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Why Is Frederick A. Valeriote Influential?
(Suggest an Edit or Addition)Frederick A. Valeriote's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Comparison of the Sensitivity of Normal Hematopoietic and Transplanted Lymphoma Colony-Forming Cells to Chemotherapeutic Agents Administered In Vivo (1966) (498)
- Total structures of cryptophycins, potent antitumor depsipeptides from the blue-green alga Nostoc sp. strain GSV 224 (1994) (247)
- Proliferation-dependent cytotoxicity of anticancer agents: a review. (1975) (231)
- Synergistic interaction of anticancer agents: a cellular perspective. (1975) (196)
- Combined effect of x radiation and 5-fluorouracil on survival of transplanted leukemic cells. (1971) (172)
- Structure determination, conformational analysis, chemical stability studies, and antitumor evaluation of the cryptophycins. Isolation of 18 new analogs from Nostoc sp. strain GSV 224 (1995) (154)
- Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family. (2004) (138)
- Effects of a low-fat diet on levels of oxidative damage to DNA to human peripheral nucleated blood cells. (1991) (132)
- Asperazine, a Selective Cytotoxic Alkaloid from a Sponge-Derived Culture of Aspergillus niger. (1997) (123)
- Symplostatin 1: A dolastatin 10 analogue from the marine cyanobacterium Symploca hydnoides. (1998) (120)
- Comparison of fascaplysin and related alkaloids: a study of structures, cytotoxicities, and sources. (2004) (115)
- Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo. (1967) (111)
- Growth characteristics of a mouse plasma cell tumor. (1968) (110)
- Comparison of the dose- and timesurvival curves for normal hematopoietic and lymphoma colony-forming cells exposed to vinblastine, vincristine, arabinosylcytosine, and amethopterin. (1969) (105)
- Tantazoles, unusual cytotoxic alkaloids from the blue-green alga Scytonema mirabile (1990) (103)
- In Vivo Methods for Screening and Preclinical Testing (1997) (102)
- Isolation and Identification of Rhizoxin Analogs from Pseudomonas fluorescens Pf-5 by Using a Genomic Mining Strategy (2008) (101)
- Evolved Diversification of a Modular Natural Product Pathway: Apratoxins F and G, Two Cytotoxic Cyclic Depsipeptides from a Palmyra Collection of Lyngbya bouillonii (2010) (95)
- Lophocladines, bioactive alkaloids from the red alga Lophocladia sp. (2006) (94)
- Azonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola. (2010) (91)
- Isolation, structure determination, and biological activity of dolastatin 12 and lyngbyastatin 1 from Lyngbya majuscula/Schizothrix calcicola cyanobacterial assemblages. (1998) (86)
- The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β‐Epoxyketone Warhead from a Marine Cyanobacterium (2012) (85)
- Unusual C25 steroids produced by a sponge-derived Penicillium citrinum. (2003) (83)
- Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development (1992) (80)
- Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. (2008) (78)
- Pharmacokinetics and toxicity of continuous infusion amphotericin B in cancer patients. (1989) (75)
- Comparison of the sensitivity of hematopoietic colony-forming cells in different proliferative states to vinblastine. (1967) (71)
- Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721. (1982) (68)
- Ecdysteroids from the Antarctic tunicate Synoicum adareanum. (2007) (67)
- Discovery and development of anticancer agents from plants. (2002) (67)
- Activity of flavone acetic acid (NSC-347512) against solid tumors of mice (2004) (66)
- Effect of cyclophosphamide on the immature rat ovary. (1989) (65)
- Synergistic effect of amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea against a transplantable AKR leukemia. (1974) (62)
- Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria. (2003) (61)
- Highly N-methylated linear peptides produced by an atypical sponge-derived Acremonium sp. (2006) (60)
- Lahorenoic acids A-C, ortho-dialkyl-substituted aromatic acids from the biocontrol strain Pseudomonas aurantiaca PB-St2. (2013) (60)
- The Search for New Antitumor Drugs from Blue-Green Algae (1996) (60)
- Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms. (2009) (59)
- Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium. (2017) (57)
- Expanding the strategies in natural product studies of marine-derived fungi: a chemical investigation of penicillium obtained from deep water sediment. (2004) (56)
- Total synthesis and biological evaluation of +-kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majuscula. (2004) (56)
- Studies on the persistence of methotrexate, cytosine arabinoside, and leucovorin in serum of mice. (1969) (56)
- Schedule-dependent synergism for the combination of 1-beta-D-arabinofuranosylcytosine and daunorubicin. (1974) (55)
- Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii. (2012) (54)
- Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties. (2007) (54)
- Structures and cytotoxicities of fascaplysin and related alkaloids from two marine phyla—Fascaplysinopsis sponges and Didemnum tunicates (2003) (54)
- Antiviral and Anticancer Optimization Studies of the DNA‐binding Marine Natural Product Aaptamine (2008) (53)
- Structures and cytotoxic properties of sponge-derived bisannulated acridines. (2002) (51)
- Discovery of Solid Tumor Active Agents Using a Soft-Agar-Colony-Formation Disk-Diffusion-Assay (1992) (51)
- Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction. (2012) (51)
- Hematological recovery in the mouse following single doses of gamma radiation and cyclophosphamide. (1968) (46)
- Application of flow cytometry and cell sorting to megakaryocytopoiesis. (1979) (46)
- Discovery of cryptophycin-1 and BCN-183577: Examples of strategies and problems in the detection of antitumor activity in mice (2004) (46)
- Survival of hematopoietic and leukemic colony-forming cells in vivo following the administration of daunorubicin or adriamycin. (1972) (46)
- Is the P388 murine tumor no longer adequate as a drug discovery model? (2004) (45)
- In vivo enhancement of 5-fluorouracil cytotoxicity to AKR leukemia cells by thymidine in mice. (1978) (45)
- A randomized trial of a low-fat dietary intervention in women at high risk for breast cancer. (1997) (44)
- Survival of hematopoietic and lymphoma colony-forming cells in vivo following the administration of a variety of alkylating agents. (1972) (44)
- Palmerolide macrolides from the Antarctic tunicate Synoicum adareanum. (2011) (44)
- A chemical study of cyclic depsipeptides produced by a sponge-derived fungus. (2006) (43)
- A modular synthesis of annonaceous acetogenins. (2003) (42)
- Influence of WR2721 on DNA cross-linking by nitrogen mustard in normal mouse bone marrow and leukemia cells in vivo. (1988) (42)
- Utilizing DART mass spectrometry to pinpoint halogenated metabolites from a marine invertebrate-derived fungus. (2011) (42)
- Synergistic action of cyclophosphamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on a transplanted murine lymphoma. (1968) (42)
- Treatment of human prostate tumors PC-3 and TSU-PR1 with standard and investigational agents in SCID mice (2004) (41)
- Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. (2012) (41)
- Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes. (2009) (40)
- Laurefurenynes A–F, new Cyclic Ether Acetogenins from a Marine Red Alga, Laurencia sp. (2010) (39)
- Mitotic arrest induced by XK469, a novel antitumor agent, is correlated with the inhibition of cyclin B1 ubiquitination (2002) (39)
- Additional insights on the bastadins: isolation of analogues from the sponge Ianthella cf. reticulata and exploration of the oxime configurations. (2010) (39)
- Flavone acetic acid (NSC 347512)-induced DNA damage in Glasgow osteogenic sarcoma in vivo. (1988) (38)
- The enhanced cytotoxicity of combinations of 1-beta-D-arabinofuranosylcytosine and methotrexate. (1975) (38)
- In vivo potentiation of 5-fluorouracil cytotoxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides. (1980) (38)
- Four Classes of Structurally Unusual Peptides from Two Marine-Derived Fungi: Structures and Bioactivities. (2007) (37)
- Potentiation of anticancer agents by amphotericin B. (1981) (37)
- Cyclocinamide A. An Unusual Cytotoxic Halogenated Hexapeptide from the Marine Sponge Psammocinia (1997) (36)
- A reassignment of (-)-mycothiazole and the isolation of a related diol. (2006) (35)
- Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula. (2010) (34)
- Preclinical anticancer activity of cryptophycin-8. (1996) (34)
- Kinetics of the lethal effect of actinomycin D on normal and leukemic cells. (1973) (34)
- Potentiation of anticancer agent cytotoxicity against sensitive and resistant AKR leukemia by amphotericin B1. (1979) (33)
- Optimum time sequence for the administration of vincristine and cyclophosphamide in vivo. (1974) (33)
- Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells of mice to vinblastine administered in vivo. (1966) (32)
- RCM-based synthesis of a variety of beta-C-glycosides and their in vitro anti-solid tumor activity. (2005) (32)
- Biostructural features of additional jasplakinolide (jaspamide) analogues. (2011) (32)
- In vivo DNA cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells. (1989) (31)
- Tumor Models and the Discovery and Secondary Evaluation of Solid Tumor Active Agents (1995) (31)
- A new paradigm for the development of anticancer agents from natural products. (2006) (30)
- A model for the action of vinblastine in vivo. (1966) (30)
- Isolation and cytotoxic evaluation of marine sponge-derived norterpene peroxides. (1998) (29)
- Anticancer activity of glaucarubinone analogues. (1998) (29)
- Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges. (2008) (29)
- New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker. (2012) (28)
- Cellular quantitation of in vivo effects of 1-beta-D-arabinofuranosylcytosine on leukemia L1210. (1977) (28)
- THE COMBINED EFFECTS OF THERMAL TRAUMA AND X-IRRADIATION ON EARLY MORTALITY. (1964) (28)
- Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program. (2012) (28)
- An in vitro assay for growth-inhibiting activity of vinblastine. (1965) (28)
- Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. (2004) (28)
- Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean. (2019) (27)
- Probing the bioactive constituents from chemotypes of the sponge Psammocinia aff. bulbosa. (2007) (26)
- Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling. (2016) (26)
- Kalkitoxin Inhibits Angiogenesis, Disrupts Cellular Hypoxic Signaling, and Blocks Mitochondrial Electron Transport in Tumor Cells (2015) (25)
- Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. (2014) (25)
- Survival of Mice Bearing a Transplanted Syngeneic Lymphoma Following Treatment With Cyclophosphamide, 5-Fiuorouracil, or 1,3-Bis(2-chloroethyl)-1-nitrosourea (1967) (25)
- Pyrroloacridine alkaloids from Plakortis quasiamphiaster: structures and bioactivity. (2007) (25)
- A distinctive structural twist in the aminoimidazole alkaloids from a calcareous marine sponge: isolation and characterization of leucosolenamines A and B. (2007) (24)
- Total synthesis and structure confirmation of the annonaceous acetogenins 30(S)-hydroxybullatacin, uvarigrandin a, and 5(R)-uvarigrandin a (narumicin I?). (2003) (24)
- Phase I study and pharmacokinetics of weekly high-dose 13-cis-retinoic acid. (1985) (24)
- Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer (2016) (24)
- Potentiation of nitrogen mustard cytotoxicity by disulfiram, diethyldithiocarbamic acid, and diethylamine in mice. (1989) (24)
- Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum. (2011) (23)
- Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors. (2014) (22)
- Cellular uptake of a novel cytotoxic agent, cryptophycin‐52, by human THP‐1 leukemia cells and H‐125 lung tumor cells (1998) (21)
- The biosynthetic products of Chinese insect medicine, Aspongopus chinensis. (2012) (21)
- Cytosine arabinoside in experimental combination therapy. (1985) (21)
- Anticancer Drug Discovery and Development: Natural Products and New Molecular Models (1994) (21)
- Response of Megakaryocyte, Erythroid, and Granulocyte-Macrophage Progenitor Cells in Mouse Bone Marrow to Gamma-Irradiation and Cyclophosphamide (1979) (21)
- Response of transplanted AKR leukemia to combination therapy with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea: dose and schedule dependency. (1977) (20)
- Synthesis and anti-tumor activity of β-C-glycoside analogs of the immunostimulant KRN7000 (2004) (19)
- Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola. (2012) (19)
- Schedule-dependent cytotoxicity of 5-fluorouracil in mice. (1986) (19)
- The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling. (2016) (19)
- The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo. (2011) (18)
- Isolation of Polycavernoside D from a Marine Cyanobacterium (2015) (18)
- Alteration of the bis-tetrahydrofuran core stereochemistries in asimicin can affect the cytotoxicity. (2008) (18)
- New in vitro screening model for the discovery of antileukemic anticancer agents. (1996) (17)
- Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities. (2016) (17)
- An efficient and cost-effective approach to kahalalide F N-terminal modifications using a nuisance algal bloom of Bryopsis pennata. (2015) (17)
- Synthesis and Biological Evaluation of Novel N-phenyl-5-carboxamidyl Isoxazoles as Potential Chemotherapeutic Agents for Colon Cancer. (2012) (16)
- Potentiation of cytotoxicity of anticancer agents by several different polyene antibiotics. (1984) (16)
- Cellular aspects of the action of cytosine arabinoside. (1982) (16)
- Another Look at Pyrroloiminoquinone Alkaloids—Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues (2017) (16)
- Lipopeptides from the Tropical Marine Cyanobacterium Symploca sp. (2014) (16)
- Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents. (2019) (16)
- Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei. (2011) (15)
- Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer. (2018) (15)
- DNA damage and cytotoxicity in L1210 cells by ellipticine and a structural analogue, N-2-(diethylaminoethyl)-9-hydroxyellipticinium chloride. (1992) (15)
- Kinetics of cytotoxicity of VM-26 and VP-16-213 on L1210 leukemia and hematopoietic stem cells. (1978) (15)
- Extensive proliferative capacity of haematopoietic stem cells. (1983) (14)
- Amphotericin B potentiation of the cytotoxicity of anticancer agents against both normal hematopoietic and leukemia cells in mice. (1984) (14)
- Activity of batracylin (NSC-320846) against solid tumors of mice (1989) (14)
- Thelepamide: an unprecedented ketide-amino acid from Thelepus crispus, a marine annelid worm. (2014) (14)
- ABC synthesis and antitumor activity of a series of Annonaceous acetogenin analogs with a threo, trans, threo, trans, threo-bis-tetrahydrofuran core unit. (2007) (14)
- Dose and interval relationship for the interaction of WR-2721 and nitrogen mustard with normal and malignant cells. (1984) (13)
- Tantazoles: Unusual Cytotoxic Alkaloids from the Blue-Green Alga Scytonema mirabile. (1991) (13)
- The unexpected isolation of CTP-431, a novel thiopyrone from the sponge Cacospongia mycofijiensis. (2008) (13)
- An Array of Bengamide E Analogues Modified at the Terminal Olefinic Position: Synthesis and Antitumor Properties (2013) (13)
- Flavone acetic acid (LM 975, NSC 347512) A novel antitumor agent (2004) (12)
- Revisiting the sponge sources, stereostructure, and biological activity of cyclocinamide a. (2008) (12)
- MOPC-315 murine plasmacytoma as a model anticancer screen for human multiple myeloma. (1986) (12)
- A murine model for central nervous system leukemia and its possible relevance to human leukemia. (1975) (12)
- Kinetics of both leukemic and normal cell population reduction following 5-azacytidine. (1975) (12)
- Discovery of anticancer agents from natural products (1995) (11)
- Leptostatin: a synthetic hybrid of the cytotoxic polyketides callystatin A and leptomycin B. (2006) (11)
- PROLIFERATION-DEPENDENT CYTOTOXIC ACTION OF ANTI-CANCER AGENTS: A REVIEW (1975) (11)
- Magnetic Resonance in Experimental and Clinical Oncology (1990) (11)
- The use of cell kinetics in the development of drug combinations. (1979) (10)
- Stereochemical challenges in characterizing nitrogenous spiro-axane sesquiterpenes from the Indo-Pacific sponges Amorphinopsis and Axinyssa (2006) (10)
- Protective effects of amphotericin B against spontaneous and transplantable murine tumors. (1976) (10)
- Cytotoxic halogenated monoterpenes from Plocamium cartilagineum (2017) (10)
- Contrasting cytotoxicity kinetics of 5-azacytidine and dihydro-5-azacytidine hydrochloride in L1210 leukemia in mice. (1981) (10)
- Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp. (2019) (10)
- Cytotoxic Phyllactone Analogs from the Marine Sponge Phyllospongia papyrecea. (2017) (10)
- Potentiation of nitrogen mustard cytotoxicity to leukemia cells by sulfur-containing compounds administered in vivo. (1986) (9)
- Interaction between flavone acetic acid (LM-975, NSC 349512) and radiation in Glasgow's osteogenic sarcoma in vivo. (1990) (9)
- Pretreatment with A Small-Molecule Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor, UTL-5g, Reduced Radiation-Induced Acute Liver Toxicity in Mice (2012) (9)
- A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs. (2020) (9)
- Erratum: Expanding the strategies in natural product studies of marine-derived fungi: A chemical investigation of Penicillium obtained from deep water sediment (Journal of Natural Products (2004) 67 (362-367)) (2004) (9)
- Cryptophycin 1 cellular levels and effects in vitro using L1210 cells (1998) (9)
- Antitumour activity of N-[[1-[[2-(diethylamino)ethyl]amino]-9-oxo-9H-thioxanthen-4-yl]methyl]methanesulfonamide (WIN33377) and analogues (1994) (9)
- Analysis of Mopc‐315 Plasmacytoma By Elutriation and Flow Cytometry (1984) (8)
- Regulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptors in a GM-CSF-dependent human myeloid leukemia cell line (AML-193) by interleukin-6. (1996) (8)
- Growth characteristics of MOPC-315 plasmacytoma and response to anticancer agents. (1981) (8)
- Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides. (2015) (8)
- Synthetic Studies on Quassinoids: Transformation of (−)-Glaucarubolone into (−)-Peninsularinone. In Vivo Antitumor Evaluation of (−)-Glaucarubolone, (−)-Chaparrinone, and (−)-Peninsularinone (1998) (7)
- The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells. (2018) (7)
- Interval and sequence dependent lethal effects of cis diammine dichloroplatinum (Cis-Pt) in combination with other agents (1979) (7)
- Combined effect of cytosine arabinoside and thiopurines. (1976) (7)
- Cytotoxic effect of 5-fluorouracil plus cyclophosphamide against transplantable leukemias. (1981) (7)
- Investigation of the Physical and Bioactive Properties of Bromo- and Iodo-Containing Sponge-Derived Compounds Possessing an Oxyphenylethanamine Core. (2017) (7)
- Survival of mice bearing a transplanted syngeneic lymphoma following treatment with cyclophosphamide, 5-fluorouracil, or 1,3-bis(2-chloroethyl)-1-nitrosourea. (1968) (7)
- Marked histoincompatibility between and within sublines of AKR mice used in a syngeneic leukemia model. (1975) (7)
- Synthesis, Cytotoxicity and Genotoxicity of 10-Aza-9-oxakalkitoxin, An N,N,O-Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product. (2020) (7)
- Biological characterization of a prolonged antileukemic effect of 5-azacytidine. (1977) (7)
- Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice (1990) (7)
- Comparison of cytotoxic action of iphosphamide and cyclophosphamide. (1981) (6)
- Biochemical Modulation of Anticancer Agents: Experimental and Clinical Approaches (2011) (6)
- Discrepancy between cytotoxicity and DNA interstrand crosslinking of carboplatin and cisplatin in vivo (1990) (6)
- USE OF IN VITRO CELL COLONY ASSAYS FOR MEASURING THE CYTOTOXICITY OF CHEMOTHERAPEUTIC AGENTS TO HEMATOPOIETIC PROGENITOR CELLS COMMITTED TO MYELOID, ERYTHROID AND MEGAKARYOCYTOID DIFFERENTIATION (1977) (6)
- Growth and rejection of leukemia cells in individual mice after combined treatment with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea. (1978) (5)
- UTL-5g Lowers Elevated Blood Levels of TNF-a and TGF-? and Increases Survival Rates in Animals Treated with LPS/D-(+)-galactosamine (2014) (5)
- Head and neck cancer: Scientific perspectives in management and strategies for cure (1987) (5)
- In Vitro Metabolism and Drug-Drug Interaction Potential of UTL-5g, a Novel Chemo- and Radioprotective Agent (2014) (5)
- Using a simple HPLC approach to identify the enzymatic products of UTL-5g, a small molecule TNF-α inhibitor, from porcine esterase and from rabbit esterase. (2013) (5)
- AMPHOTERICIN B: INTERACTIONS WITH NITROSOUREAS AND OTHER ANTINEOPLASTIC DRUGS (1981) (5)
- Influence of continuous infusion of cytosine arabinoside on sequencing with daunorubicin in L1210 leukemia. (1978) (5)
- Discovery of Natural Products from Microalgae and Marine Organisms (1994) (5)
- Flavone acetic acid and plasma protein binding (2004) (5)
- Cellular drug action profile paradigm applied to XK469. (2002) (5)
- Solid Tumor Inhibitory and other Constituents of Casimiroa tetrameria (2011) (4)
- The role of cell kinetics in cancer chemotherapy. (1977) (4)
- Actinomycin D: kinetics of its lethal action on a transplantable leukemia. (1971) (4)
- The anti-MRSA compound 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) inhibits protein synthesis in Staphylococcus aureus. (2020) (4)
- The effect of x-irradiation and thermal burn on the intestinal mucosa. (1968) (4)
- Metabolism studies of a small-molecule tumor necrosis factor-alpha (TNF-α) inhibitor, UTL-5b (GBL-5b) (2012) (4)
- UTL-5g Lowers Levels of TGF-β and TNF-α Elevated by Lung Irradiation and Does Not Affect Tumor-response to Irradiation (2014) (4)
- Effects of Thermal Burn and X-Irradiation on Early Mortality.∗ (1966) (4)
- nitrosourea Against a transplantable akr leukemia. (1974) (4)
- Enhancement of the lethal effects of adriamycin (adria) by combining with other agents. Abstr. (1975) (4)
- In vitro screening model for the detection of agents active against myelogenous leukemia. (1998) (3)
- Insights into the human gut microbiome - A review (2018) (3)
- RCM-Based Synthesis of a Variety of β-C-Glycosides and Their in vitro anti-Solid Tumor Activity. (2005) (3)
- Cytotoxicity of adriamycin combined with methotrexate against L1210 leukemia in mice. (1980) (3)
- Drug Discovery — 1990 (1992) (3)
- Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8S Configuration. (2020) (3)
- Comparison of the cytotoxicity of 5-(3,3-bis(2-chloroethyl)-1-triazeno)imidazole-4-carboxamide (NSC-82196) on normal and leukemic colony-forming cells. (1971) (3)
- Effect of dose fractionation of daunorubicin on survival of leukemic cells. (1980) (3)
- Biochemical Modulation of Anticancer Agents: An Overview (1986) (3)
- Development and Validation of a Simple Method for the Detection of Fascaplysin in Plasma (2012) (3)
- Conceptual basis for use of chemotherapeutic agents and their pharmacology. (1976) (3)
- Effect of a transplantable leukemia on hematopoietic stem cells in AKR mice. (1978) (3)
- Detoxification ability and toxicity of quinones in mouse and human tumor cell lines used for anticancer drug screening (2004) (3)
- A liquid chromatography with tandem mass spectrometry method for simultaneous determination of UTL-5g and its metabolites in human plasma. (2015) (2)
- Modification of Cell Sensitivity to Anticancer Agents by Polyenes (1986) (2)
- Inhibition of hTERT in pancreatic cancer cells by pristimerin involves suppression of epigenetic regulators of gene transcription (2017) (2)
- Retention of 1-beta-D-arabinofuranosylcytosine in vitro--a source of experimental error. (1977) (2)
- 31P and 2H MRS Studies of Flavone Acetic Acid and Analogues (1990) (2)
- Development and validation of a rapid method for the detection of latrunculol A in plasma (2009) (2)
- A-phase II study of intravenous 6-thioguanine (NSC-752) in multiple myeloma. A Southwest Oncology Group study. (1990) (2)
- Inhibition of macromolecular synthesis by cryptophycin-52 (2002) (2)
- HPLC Plasma Assay of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside, from Sycamore Leaves (2015) (2)
- Basic and Clinical Applications of Flow Cytometry (1996) (2)
- Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation. (2017) (2)
- Analytical Characterization of Fatty Acids Composition of Bioactive Stem Oil of Maytenus royleanus by Gas Chromatography Mass Spectrometry (2013) (1)
- Unusual C25 Steroids Produced by a Sponge‐Derived Penicillium citrinum. (2004) (1)
- Potentiation of tumor cytotoxicity of different anticancer agents by amphotericin b. Abstr. (1979) (1)
- Laurefurenynes A—F, New Cyclic Ether Acetogenins from a Marine Red Alga, Laurencia sp. (2010) (1)
- Potentiation by amphotericin B of the cytotoxicity of anticancer agents against MOPC-315 plasmacytoma and lewis lung carcinoma (2004) (1)
- A phase II study of intravenous 6-thioguanine (NSC-752) in multiple myeloma (2004) (1)
- Isolation and Identification of Rhizoxin Analogs from Pseudomonas fluorescens Pf-5 by Using a Genomic Mining Strategy (cid:1) † (2008) (1)
- Immunochemotherapy of transplantable murine leukemia with amphotericin b (amb) and bcnu. Abstr. (1976) (1)
- Schedule-dependent potentiation of lomustine cytotoxicity by amphotericin B in mice. (1986) (1)
- Schedule dependence of the synergistic lethal effects of cyclophosphamide (CY) and 1,3 bis(2 chloroethyl) 1 nitrosurea (BCNU) (1974) (1)
- QUANTITATION OF THE IMMUNE REJECTION OF ALLOTRANSPLANTED AKR LEUKEMIC CELLS (1976) (1)
- Quantitative measurements of the efficacy of new anti-cancer agents on fresh human AML cells by using multivariate flow analysis. (1996) (1)
- Delayed cytotoxicity of 5 azacytidine (AzaC) (1975) (1)
- Comparison of clonogenic and increase in lifespan assays (1980) (1)
- Schedule-dependent antitumor and toxic effects of thymidine and 5-fluorouracil in AKR and L1210 leukemias (2004) (1)
- Survival of L1210 leukemia cells and normal hematopoietic stem cells following in vivo administration of cyclocytidine (2004) (1)
- Survival of hematopoietic and leukemic colony-forming cells in vivo after administration of mitomycin C or porfiromycin. (1973) (1)
- Effects of a low fat diet on oxidative DNA damage in nucleated peripheral blood cells of women at high risk for breast cancer (1990) (1)
- Arctin and Arctigenin as a Potential Treatment for Solid Tumors (2019) (1)
- Enhancement of Bone Marrow CD41+ Megakaryocytes as well as Modulation of TNF-a, IL-12, and IL-5 by a Novel Small Molecule, UTL-5g, in Mice Treated with Cisplatin (2015) (1)
- Delayed cytotoxicity of 5-azacytidine (azac). Abstr. (1975) (0)
- In Vitro anticancer studies on Cantron® and its constituents (2013) (0)
- Chemotherapy of L1210 leukemia with 5-azacytidine in combination with vincristine, adriamycin, or beta-cytosine arabinoside. (1981) (0)
- Identification of the Metabolites of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR), Extracted from American Sycamore (2018) (0)
- Azonazine, a Novel Dipeptide from a Hawaiian Marine Sediment‐Derived Fungus, Aspergillus insulicola. (2011) (0)
- DNA Damage and Cytotoxicity in LI 210 Cells by Ellipticine and a Structural Analogue, A^-2-(Diethylaminoethyl)-9-hydroxyellipticinium Chloride1 (2006) (0)
- Growth characteristics and response to anticancer agents of MOPC 315 plasmacytoma (1977) (0)
- PREPARATION AND CYTOTOXICITY EVALUATION OF ACETYLATED FIJIANOLIDES (A.K.A. LAULIMALIDE) (2018) (0)
- Biology and therapy of acute leukemia : proceedings of the Seventeenth Annual Detroit Cancer Symposium, Detroit, Michigan, April 12-13, 1984 (1985) (0)
- Azacytidine (aza) combination with vincristine (vcr), arabino- sylcytosine (ara) or adriamycin (adr). Abstr. (1977) (0)
- Comparison of cytotoxicity of single dose and infusion of alkylating agents. (1985) (0)
- Abstract 366: Arctin and arctigenin as a potential treatment for solid tumors (2019) (0)
- Experimental Rationale for Therapy in the Treatment of Acute Leukemia (1985) (0)
- Isolation of Puupehenone analogs and further development of the structure activity relationship within this compound class (2008) (0)
- PROCEEDINGS, XI INTERNATIONAL CANCER CONGRESS, FLORENCE 1974 (1975) (0)
- Daclatasvir, an antiviral drug, downregulates Tribbles 2 pseudokinase and re-sensitizes enzalutamide resistant prostate cancer cells. (2023) (0)
- Survival of leukemic colony forming units (LCFU) in tumor bearing mice following amphotericin B (AmB) and 1,3 bis(2 chloroethyl) 1 nitrosourea (BCNU) administration (1974) (0)
- The Active Metabolite of UTL-5g, 5-Methylisoxazole-3-Carboxylic Acid, is Anti-Inflammatory and Reduces Doxorubicin-Induced Cardiac Toxicity (2016) (0)
- Therapeutic quassionoidpræparationer having antineoplastic, antiviral activity and herbistatisk (1995) (0)
- Further investigations into abeohyousterone, a new ecdysteroid from the Antarctic tunicate Synoicum adareanum (2008) (0)
- Novel Animal Model for Ventricular Ejection Fraction Measured by MRI (2021) (0)
- Protein Informatics-based analysis of the mechanism of action of Peninsularinone: A novel solid-tumor selective anticancer drug (2006) (0)
- The Unexpected Isolation of CTP‐431, a Novel Thiopyrone from the Sponge Cacospongia mycofijiensis. (2009) (0)
- A new brominated indole from Haplosclerida with selective cytotoxicity against the PANC-1 tumor cell line (2015) (0)
- Kinetics of dihydroazacytidine (DHAza) cytotoxicity differ from 5-azacytidine (Aza) (1979) (0)
- Hoiamide D (I), a Marine Cyanobacteria‐Derived Inhibitor of p53/MDM2 Interaction. (2012) (0)
- A mathematical model for alkaline elution curve fitting and some applications (1985) (0)
- Correction to "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp." (2020) (0)
- From 5-azacytidine (aza). Abstr. (1979) (0)
- Biology and Therapy of Acute Leukemia (1985) (0)
- Psymberin, a Potent Sponge‐Derived Cytotoxin from Psammocinia Distantly Related to the Pederin Family. (2004) (0)
- DNA Damage and Cytotoxicity in LI 210 Cells by Ellipticine and a Structural Analogue , A ^-2-( Diethylaminoethyl )-9-hydroxyellipticinium Chloride 1 (2006) (0)
- Basic and clinical applications of flow cytometry : proceedings of the 24th Annual Detroit Cancer Symposium, Detroit, Michigan, USA, April 30, May 1 and 2, 1992 (1996) (0)
- Prophylactic effect of amphotericin b (amb) in spontaneous and trans- plantable murine tumor systems. Abstr. (1975) (0)
- In Vitro Model for Defining Neurotoxicity of Anticancer Agents (2015) (0)
- Cytotoxicity Studies of Fijianolide (a.k.a. Laulimalide) Acetylated Derivatives Against Pancreatic Cancer Cell lines to Investigate New Paths For Therapeutic Development (2015) (0)
- Therapeutic Quassinoid preparations with antineoplastic, antiviral and herb ista genetic effect (1995) (0)
- Using Accelerated Solvent Extraction (ASE) followed by parallel chromatography to rapidly pinpoint new chemistry and scale-up the isolation of bioactive marine natural products for in vivo evaluation (2008) (0)
- From FISH to Proteomics (2005) (0)
- Total Synthesis and Biological Evaluation of (+)-Kalkitoxin, a Cytotoxic Metabolite of the Cyanobacterium Lyngbya majuscula. (2004) (0)
- Third anticancer drug discovery and development symposium (2004) (0)
- Potentiation of ccnu cytotoxicity by amphotercin b (amb). Abstr. (1983) (0)
- Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium. (2021) (0)
- The kinetics of lethality of actinomycin d (act-d) on normal and leukemic cells. Abstr. (1973) (0)
- N-2-(Diethylaminoethyl)-9-hydroxyellipticinium Chloride a Structural Analogue, DNA Damage and Cytotoxicity in L1210 Cells by Ellipticine and (2013) (0)
- Metabolism studies of a small-molecule tumor necrosis factor-alpha (TNF-α) inhibitor, UTL-5b (GBL-5b) (2011) (0)
- Quantitation of development of actinomycin-d (act-d) resistance in vivo in akr leukemia and its modification by amphotericin b (amb). Abstr. (1978) (0)
- Pharmacology of i.v. amphotericin B (AmB) in mouse and humans and potentiation of CCNU cytotoxicity in AKR mouse (1985) (0)
- Synthetic Studies on Quassinoids: Transformation of (‐)‐Glaucarubolone into (‐)‐Peninsularinone. In vivo Antitumor Evaluation of (‐)‐Glaucarubolone, (‐)‐Chaparrinone, and (‐)‐Peninsularinone. (1998) (0)
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What Schools Are Affiliated With Frederick A. Valeriote?
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