Frederick Alt

Q: What Schools Are Affiliated With Frederick Alt

Frederick Alt is affiliated with the following schools: Stanford University, University of Tokushima, Gifu Pharmaceutical University, Osaka University, University of California, San Francisco, Columbia University, Brandeis University, Kyoto University, Harvard University, Hokkaido University, Washington University in St. Louis, University of Texas at Austin

Frederick Alt's AcademicInfluence.com Rankings

Frederick Alt

Biology

#275

World Rank

#498

Historical Rank

#161

USA Rank

Genetics

#77

World Rank

#110

Historical Rank

#51

USA Rank

biology Degrees

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Biology

Frederick Alt's Degrees

PhD Biochemistry Stanford University
Doctorate Medicine Stanford University

Why Is Frederick Alt Influential?

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According to Wikipedia, Frederick W. Alt is an American geneticist. He is a member of the Immunology section of the National Academy of Sciences and a Charles A. Janeway Professor of Pediatrics, and Professor of Genetics at Harvard Medical School. He is the Director of the Program in Cellular and Molecular Medicine at the Boston Children's Hospital. He is a Howard Hughes Medical Institute investigator, since 1987.

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Frederick Alt's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase (2004) (3112)
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement (1992) (2793)
An early haematopoietic defect in mice lacking the transcription factor GATA-2 (1994) (1470)
Plasma cell differentiation requires the transcription factor XBP-1 (2001) (1271)
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy (2008) (1258)
Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 (2006) (1229)
SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation (2008) (1226)
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α (2007) (1199)
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. (1995) (1155)
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation (2007) (1116)
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. (1996) (1109)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice (2003) (1088)
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells (2006) (1084)
The Mechanism and Regulation of Chromosomal V(D)J Recombination (2002) (929)
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation (1995) (894)
DNA Repair, Genome Stability, and Aging (2005) (857)
SIRT 3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation (2010) (834)
The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages (1996) (795)
Defective B cell development and function in Btk-deficient mice. (1995) (795)
SIRT3 regulates fatty acid oxidation via reversible enzyme deacetylation (2009) (766)
Transcription-targeted DNA deamination by the AID antibody diversification enzyme (2003) (762)
Ordered rearrangement of immunoglobulin heavy chain variable region segments. (1984) (721)
Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. (1999) (698)
A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis (1998) (674)
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. (2011) (671)
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. (2006) (669)
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments (1985) (667)
Transposition and amplification of oncogene-related sequences in human neuroblastomas (1983) (663)
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions. (1982) (656)
SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging (2008) (651)
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. (1994) (640)
Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines (1984) (611)
IgH class switching and translocations use a robust non-classical end-joining pathway (2007) (605)
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. (2006) (592)
The CBFβ Subunit Is Essential for CBFα2 (AML1) Function In Vivo (1996) (591)
SIRT1 controls endothelial angiogenic functions during vascular growth. (2007) (589)
Late embryonic lethality and impaired V (D)J recombination in mice lacking DNA ligase IV (1998) (586)
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair (2004) (584)
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development (2000) (584)
Development of the primary antibody repertoire. (1987) (582)
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases (2014) (582)
Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. (2006) (568)
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX (2002) (564)
Tissue-specific regulation of SIRT1 by calorie restriction. (2008) (547)
Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells (1984) (528)
Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations (2012) (528)
Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally (2008) (520)
Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. (1998) (519)
Histone H2AX A Dosage-Dependent Suppressor of Oncogenic Translocations and Tumors (2003) (514)
Differential expression of myc family genes during murine development (1986) (513)
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. (2000) (503)
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination (1995) (474)
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends (1980) (472)
Growth retardation and leaky SCID phenotype of Ku70-deficient mice. (1997) (470)
Impairment of V(D)J recombination in double-strand break repair mutants. (1993) (468)
Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. (1993) (463)
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction (1998) (453)
Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus. (1993) (440)
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. (1998) (438)
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. (1993) (436)
Unrepaired DNA Breaks in p53-Deficient Cells Lead to Oncogenic Gene Amplification Subsequent to Translocations (2002) (433)
A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes (1986) (424)
Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells (2011) (424)
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. (2010) (424)
Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes (1981) (423)
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. (1997) (416)
Impaired Viability and Profound Block in Thymocyte Development in Mice Lacking the Adaptor Protein SLP-76 (1998) (409)
Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase (1986) (409)
Mechanism and control of class-switch recombination. (2002) (408)
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. (1993) (405)
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets (2004) (405)
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene (1995) (404)
Mechanisms of Programmed DNA Lesions and Genomic Instability in the Immune System (2013) (403)
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing (2003) (398)
Binding of myc proteins to canonical and noncanonical DNA sequences (1993) (395)
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation. (2001) (393)
Regulation of the assembly and expression of variable-region genes. (1986) (385)
Regulation of Genome Rearrangement Events during Lymphocyte Differentiation (1986) (384)
RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. (1993) (372)
The role of DNA breaks in genomic instability and tumorigenesis (2003) (371)
The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. (2000) (364)
Unraveling V(D)J Recombination Insights into Gene Regulation (2004) (363)
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination (2004) (350)
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility (2001) (343)
The cellular response to general and programmed DNA double strand breaks. (2004) (335)
DNA double strand break repair and chromosomal translocation: Lessons from animal models (2001) (333)
Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching (1998) (329)
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. (1998) (328)
Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements. (1996) (324)
Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. (1992) (324)
Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene (1995) (321)
N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation. (2000) (320)
53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions (2013) (317)
Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. (2005) (310)
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation (2000) (308)
The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. (1996) (305)
The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism (1988) (299)
The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow. (1998) (299)
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. (2006) (291)
Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector (2009) (291)
Evolution of the immunoglobulin heavy chain class switch recombination mechanism. (2007) (282)
The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates (2011) (282)
Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. (2002) (281)
A class switch control region at the 3′ end of the immunoglobulin heavy chain locus (1994) (280)
The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice (1994) (279)
Bclx regulates the survival of double-positive thymocytes. (1995) (277)
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. (1994) (277)
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation (2005) (275)
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. (2008) (274)
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner (2009) (266)
CTCF Binding Elements Mediate Control of V(D)J Recombination (2011) (264)
Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production (1998) (263)
Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching (1988) (263)
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. (2005) (256)
Recombination between immunoglobulin variable region gene segments is enhanced by transcription (1986) (256)
Calorie restriction alters mitochondrial protein acetylation (2009) (251)
Cdc42 is required for PIP2-induced actin polymerization and early development but not for cell viability (2000) (250)
Activating Notch1 mutations in mouse models of T-ALL. (2005) (247)
Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells (1984) (246)
Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells (2003) (246)
RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein. (1997) (244)
Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks. (2012) (244)
The role of the non‐homologous end‐joining pathway in lymphocyte development (2004) (241)
myc family oncogenes in the development of normal and neoplastic cells. (1991) (235)
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair. (2007) (235)
Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes (2014) (233)
S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. (1994) (229)
Activated expression of the N-myc gene in human neuroblastomas and related tumors. (1984) (228)
Microbial colonization influences early B-lineage development in the gut lamina propria (2013) (228)
The influence of transcriptional orientation on endogenous switch region function (2003) (223)
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. (2004) (223)
Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus (1982) (222)
Secondary genomic rearrangement events in pre‐B cells: VHDJH replacement by a LINE‐1 sequence and directed class switching. (1986) (220)
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease. (2013) (219)
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells. (2000) (216)
Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation. (1994) (216)
Control of sister chromatid recombination by histone H2AX. (2004) (216)
A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon. (1993) (216)
Human N-myc is closely related in organization and nucleotide sequence to c-myc (1986) (214)
Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. (1997) (212)
Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains. (1998) (208)
Defective DNA Repair and Increased Genomic Instability in Artemis-deficient Murine Cells (2003) (208)
Convergent Transcription at Intragenic Super-Enhancers Targets AID-Initiated Genomic Instability (2014) (207)
Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice (1990) (205)
CD3ε-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2−/− mice in the absence of TCR β chain expression (1994) (205)
Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus. (1993) (203)
Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression. (2000) (203)
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. (2002) (203)
ATM Damage Response and XLF Repair Factor are Functionally Redundant In Joining DNA Breaks (2010) (201)
Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. (1990) (201)
Transcription-induced Cleavage of Immunoglobulin Switch Regions by Nucleotide Excision Repair Nucleases in Vitro* (2000) (201)
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells (2016) (200)
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase. (2007) (200)
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain (1980) (199)
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. (2000) (199)
N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization (1988) (198)
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac‐mediated actin‐based motility (2003) (195)
Function of the TCRα Enhancer in αβ and γδ T Cells (1997) (193)
RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues. (1999) (193)
Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines (1982) (193)
Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 (2010) (191)
AID in somatic hypermutation and class switch recombination. (2006) (190)
Developmentally regulated and strain-specific expression of murine VH gene families (1988) (188)
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. (2009) (188)
B cell development in mice that lack one or both immunoglobulin kappa light chain genes. (1993) (188)
LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells. (1993) (186)
TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice. (2001) (186)
Elucidation of IgH intronic enhancer functions via germ-line deletion. (2005) (184)
Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells (1988) (184)
Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination. (2008) (183)
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4 (2010) (183)
Proapoptotic BID is required for myeloid homeostasis and tumor suppression. (2003) (182)
The Igκ 3′ Enhancer Influences the Ratio of Igκ versus Igλ B Lymphocytes (1996) (180)
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule (2000) (179)
Batf controls the global regulators of class switch recombination in both B and T cells (2011) (178)
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. (2002) (177)
Activation of V kappa gene rearrangement in pre‐B cells follows the expression of membrane‐bound immunoglobulin heavy chains. (1987) (177)
Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer (2003) (176)
H2AX May Function as an Anchor to Hold Broken Chromosomal DNA Ends in Close Proximity (2004) (175)
Enhanced expression of the N-myc gene in Wilms' tumors. (1986) (175)
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice. (2003) (174)
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity (2010) (174)
Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility. (1996) (174)
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires (2016) (173)
Growth Retardation, Early Death, and DNA Repair Defects in Mice Deficient for the Nucleotide Excision Repair Enzyme XPF (2004) (172)
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing (2016) (171)
VHDJH formation and DJH replacement during pre‐B differentiation: non‐random usage of gene segments. (1986) (169)
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. (2011) (167)
Vav Family Proteins Couple to Diverse Cell Surface Receptors (2000) (167)
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. (2001) (167)
The Lingering Enigma of the Allelic Exclusion Mechanism (2004) (164)
Deletion of the Igκ Light Chain Intronic Enhancer/Matrix Attachment Region Impairs but Does Not Abolish VκJκ Rearrangement (1996) (164)
Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development (2001) (164)
WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo (2005) (162)
Class Switching in B Cells Lacking 3′ Immunoglobulin Heavy Chain Enhancers (1998) (160)
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development (2008) (158)
An evolutionarily conserved target motif for immunoglobulin class-switch recombination (2004) (157)
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. (2004) (156)
Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer (2006) (156)
N-myc can cooperate with ras to transform normal cells in culture. (1985) (154)
Mechanisms that promote and suppress chromosomal translocations in lymphocytes. (2011) (154)
Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. (1997) (153)
Regulated progression of a cultured pre-B-cell line to the B-cell stage (1985) (152)
T cell responses in calcineurin A alpha-deficient mice (1996) (151)
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes. (1996) (150)
SIRT6 in DNA repair, metabolism and ageing (2008) (145)
Mechanisms promoting translocations in editing and switching peripheral B cells (2009) (140)
Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion. (1999) (139)
Structure and expression of the human and mouse T4 genes. (1987) (139)
Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line (1982) (137)
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. (2000) (135)
Mechanism and developmental program of immunoglobulin gene rearrangement in mammals. (1989) (134)
Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. (2004) (133)
Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. (2003) (131)
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes (2015) (130)
Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression (2005) (130)
Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. (2013) (130)
Deletion of a conserved Il4 silencer impairs T helper type 1–mediated immunity (2004) (128)
The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. (2010) (127)
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. (2002) (126)
Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts (1991) (126)
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1) (2012) (122)
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes (2015) (119)
Isolation of scid pre‐B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins. (1989) (119)
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells (2007) (118)
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency. (2013) (117)
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice (2009) (116)
Early Embryonic Lethality Due to Targeted Inactivation of DNA Ligase III (2006) (116)
Immunoglobulin VH gene expression in human B cell lines and tumors: biased VH gene expression in chronic lymphocytic leukemia. (1989) (116)
Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching. (1993) (113)
XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. (2006) (113)
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination (2011) (112)
Sequence and organization of the human T cell δ chain gene (1988) (111)
Antibody Class Switching Mediated by Yeast Endonuclease-Generated DNA Breaks (2007) (111)
The human myc gene family. (1986) (110)
Structure and expression of the murine N-myc gene. (1986) (110)
AID Recognizes Structured DNA for Class Switch Recombination. (2017) (109)
Complementary functions of ATM and H2AX in development and suppression of genomic instability (2008) (109)
Structure and expression of germ line immunoglobulin gamma 2b transcripts (1988) (109)
Essential roles of the κ light chain intronic enhancer and 3′ enhancer in κ rearrangement and demethylation (2002) (109)
Developmental regulation of V(D)J recombination and lymphocyte differentiation. (1996) (108)
Mre11: roles in DNA repair beyond homologous recombination (2009) (107)
Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination. (2015) (107)
Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. (2004) (104)
Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions. (1999) (103)
Activated Ras Signals Developmental Progression of Recombinase-activating Gene (RAG)-deficient Pro-B Lymphocytes (1999) (103)
Phosphatidylinositol 3-Kinase (PI3K) δ blockade increases genomic instability in B cells (2017) (103)
The human myc gene family: structure and activity of L-myc and an L-myc pseudogene. (1987) (102)
Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene (1989) (101)
Surface IgM mediated regulation of RAG gene expression in E mu‐N‐myc B cell lines. (1992) (101)
DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination (2008) (101)
Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status (1993) (100)
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations. (2006) (99)
Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice (2003) (99)
Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination (2011) (99)
Isolation of amplified DNA sequences from IMR-32 human neuroblastoma cells: facilitation by fluorescence-activated flow sorting of metaphase chromosomes. (1983) (98)
Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes. (1992) (97)
Gene rearrangement and B-cell development. (1993) (97)
A DNA repair defect in Chinese hamster ovary cells affects V(D)J recombination similarly to the murine scid mutation. (1994) (95)
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus. (1999) (95)
Internal IgH class switch region deletions are position-independent and enhanced by AID expression (2002) (94)
Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency (2010) (93)
Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon (1990) (92)
p63 and p73 are not required for the development and p53-dependent apoptosis of T cells. (2004) (92)
Gene Transfer into Hepatocytes Mediated by Helper Virus-Free HSV/AAV Hybrid Vectors (1997) (92)
Wiskott–Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development (2007) (91)
The Fundamental Role of Chromatin Loop Extrusion in Physiological V(D)J Recombination (2019) (91)
Innate immune response to encephalomyocarditis virus infection mediated by CD1d (2003) (91)
Glycan Masking Focuses Immune Responses to the HIV‐1 CD4‐Binding Site and Enhances Elicitation of VRC01‐Class Precursor Antibodies (2018) (91)
IgH enhancer‐mediated deregulation of N‐myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c‐myc expression. (1989) (90)
E mu N- and E mu L-myc cooperate with E mu pim-1 to generate lymphoid tumors at high frequency in double-transgenic mice. (1991) (90)
Orientation-Specific Joining of AID-initiated DNA Breaks Promotes Antibody Class Switching (2015) (90)
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation (2019) (89)
Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways (1998) (89)
Regulation of immunoglobulin light chain isotype expression. (1998) (88)
Fundamental Roles of Chromatin Loop Extrusion in Antibody Class Switching (2019) (88)
Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions (2011) (88)
Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells (2016) (87)
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching (2008) (87)
Mechanism of tandem duplication formation in BRCA1 mutant cells (2017) (87)
Differential activation of transcription versus recombination of transgenic T cell receptor beta variable region gene segments in B and T lineage cells (1994) (87)
A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination (1993) (84)
Expression and function of myc family genes. (1990) (84)
Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments. (2000) (84)
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. (2006) (83)
Hypomorphic Rag mutations can cause destructive midline granulomatous disease. (2010) (83)
CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning (2018) (82)
ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification (2010) (82)
Impaired V(D)J Recombination and Lymphocyte Development in Core RAG1-expressing Mice (2003) (81)
CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression. (1994) (81)
Expression of Iμ-Cγ hybrid germline transcripts subsequent to immunoglobulin heavy chain class switching (1994) (81)
Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus. (1998) (81)
Methods for cloning and analysis of eukaryotic genes (1990) (80)
Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus. (2008) (79)
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line (2016) (78)
Structure and expression of germline immunoglobulin gamma 3 heavy chain gene transcripts: implications for mitogen and lymphokine directed class-switching. (1990) (78)
SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. (1998) (77)
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. (2003) (76)
CD2ϵ and CD3ξ cytoplasmic domains can independently generate signals for T cell development and function (1995) (75)
Long-range Oncogenic Activation of IgH/c-myc Translocations by the IgH 3’ Regulatory Region (2009) (75)
Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. (1995) (74)
Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus. (1996) (74)
Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining (2013) (74)
VH gene usage in humans: biased usage of the VH6 gene in immature B lymphoid cells (1991) (72)
Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40. (1997) (71)
Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs. (2001) (70)
An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression. (2015) (69)
DNA double-strand breaks as drivers of neural genomic change, function, and disease. (2018) (69)
Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation. (2002) (68)
Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras. (1999) (68)
Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability (2009) (68)
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of rb, mimics the human disease (2008) (68)
Influence of switch region length on immunoglobulin class switch recombination. (2005) (67)
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes (2010) (67)
Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function. (2012) (67)
Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair (2012) (67)
Early human IgH gene assembly in Epstein-Barr virus-transformed fetal B cell lines. Preferential utilization of the most JH-proximal D segment (DQ52) and two unusual VH-related rearrangements (1989) (67)
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice (2000) (66)
Tissue-specific regulation of SIRT 1 by calorie restriction (2008) (66)
High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination (1990) (66)
Developmental Regulation of TCRδ Locus Accessibility and Expression by the TCRδ Enhancer (1999) (66)
Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions (2008) (66)
Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. (2004) (65)
Constitutive Bcl-2 expression during immunoglobulin heavy chain-promoted B cell differentiation expands novel precursor B cells. (1997) (65)
Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing (2017) (65)
Functional overlaps between XLF and the ATM-dependent DNA double strand break response. (2014) (63)
Structure and expression of the murine L‐myc gene. (1987) (62)
SIRT 3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome (2011) (62)
Antigen-specific B cell receptor sensitizes B cells to infection by influenza virus (2013) (60)
Site-specific recombination between immunoglobulin D and JH segments that were introduced into the genome of a murine pre-B cell line (1984) (60)
Assembly of Productive T Cell Receptor δ Variable Region Genes Exhibits Allelic Inclusion (1998) (59)
Synthesis of immunoglobulin mu chain gene products precedes synthesis of light chains during B-lymphocyte development. (1981) (59)
Function and Control of Recombination‐Activating Gene Activity a (1992) (59)
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell. 1985. 40: 271-281. (2012) (59)
Antigen-Independent Appearance of Recombination Activating Gene (Rag)-Positive Bone Marrow B Cells in the Spleens of Immunized Mice (2000) (59)
The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus (1995) (58)
Molecular characterization of the lymphoid V(D)J recombination activity. (1989) (58)
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors (2018) (58)
The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes. (1996) (58)
CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination (2015) (57)
Expression of J chain RNA in cell lines representing different stages of B lymphocyte differentiation (1981) (57)
A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation (2009) (56)
Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program (2011) (55)
Allelic Exclusion of the T Cell Receptor β Locus Requires the Sh2 Domain–Containing Leukocyte Protein (Slp)-76 Adaptor Protein (1999) (55)
Accessibility control of variable region gene assembly during T‐cell development (1998) (54)
Reevaluation of 3'Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation. (1998) (54)
Probing immune functions in RAG-deficient mice. (1994) (54)
Cloning and sequence analysis of the VH and VL regions of an anti-myelin/DNA antibody from a patient with peripheral neuropathy and chronic lymphocytic leukemia. (1990) (54)
EccDNAs are apoptotic products with high innate immunostimulatory activity (2021) (53)
RAG2 is regulated differentially in B and T cells by elements 5' of the promoter. (1999) (53)
Function of the TCR alpha enhancer in alphabeta and gammadelta T cells. (1997) (53)
Amplification and rearrangement of DNA sequences from the chromosomal region 2p24 in human neuroblastomas. (1986) (53)
IL-2 receptor α chain expression during early B lymphocyte differentiation (1994) (52)
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning (2020) (52)
Chromatin dynamics and locus accessibility in the immune system (2003) (51)
Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development. (2005) (51)
BCR selection and affinity maturation in Peyer’s patch germinal centres (2020) (51)
Dramatically Increased Rearrangement and Peripheral Representation of Vβ14 Driven by the 3′Dβ1 Recombination Signal Sequence (2003) (51)
Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells. (1994) (50)
Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre‐B cells. (1987) (50)
Myc family of cellular oncogenes (1987) (50)
Ig heavy chain class switching in Rag-deficient mice. (1998) (49)
Are myc proteins transcription factors? (1990) (49)
Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase. (2008) (49)
A novel regulatory myosin light chain gene distinguishes pre‐B cell subsets and is IL‐7 inducible. (1992) (49)
Bone marrow B lymphocyte development in c-abl-deficient mice. (1995) (49)
DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions (2018) (48)
An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching. (1998) (48)
Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies. (1986) (47)
Molecular genetic characterization of XRCC4 function. (1997) (47)
Abnormal peripheral lymphocyte function in c-abl mutant mice. (1996) (47)
T helper cell membranes promote IL-4-independent expression of germ-line C gamma 1 transcripts in B cells. (1992) (47)
Antibody diversity: one enzyme to rule them all (2004) (47)
Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid mice (1990) (47)
Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. (2009) (46)
Immunoglobulin heavy chain gene rearrangements in X‐linked agammaglobulinemia (1986) (46)
The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination. (1999) (46)
VH to VHDJH rearrangement is mediated by the internal VH heptamer. (1990) (45)
The Role of Bruton's Tyrosine Kinase in B‐Cell Development and Function in Mice and Man a (1995) (45)
Differential regulation of the N-myc gene in transfected cells and transgenic mice (1990) (45)
Highly sensitive and unbiased approach for elucidating antibody repertoires (2016) (45)
Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability. (2020) (44)
Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis. (1999) (44)
Discordance between IgA switching at the DNA level and IgA expression at the mRNA level in IgA-deficient patients. (1999) (43)
Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome (2010) (43)
High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains. (1987) (43)
Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement. (1996) (42)
Deficiency in the Nuclease Activity of Xeroderma Pigmentosum G in Mice Leads to Hypersensitivity to UV Irradiation (2004) (41)
Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells. (2003) (41)
Loop Extrusion Mediates Physiological IgH Locus Contraction For RAG Scanning (2021) (40)
Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining (2011) (40)
Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination (2010) (39)
VDJ recombination. (1992) (39)
Phosphoinositide 3-kinase knockout mice: role of p85alpha in B cell development and proliferation. (1999) (39)
Vav3 is regulated during the cell cycle and effects cell division (2002) (39)
T cell receptor (TCR) α/δ locus enhancer identity and position are critical for the assembly of TCR δ and α variable region genes (2003) (39)
RAG Chromatin Scanning During V(D)J Recombination and Chromatin Loop Extrusion are Related Processes. (2018) (39)
Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomas (2008) (38)
Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line (1984) (38)
Localized Epigenetic Changes Induced by DH Recombination Restricts Recombinase to DJH Junctions (2012) (37)
DNA melting initiates the RAG catalytic pathway (2018) (37)
A Single DH Gene Segment Creates Its Own Unique CDR-H3 Repertoire and Is Sufficient for B cell Development and Immune Function1 (2005) (37)
DNA binding by N- and L-Myc proteins. (1993) (36)
Potential targets for autosomal SCID mutations. (1995) (36)
Immunoglobulin genes in transgenic mice (1985) (36)
Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies (2017) (36)
Generation of normal lymphocyte populations by Rb-deficient embryonic stem cells (1993) (35)
IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances (2014) (35)
IgH enhancer deregulated expression of L‐myc: abnormal T lymphocyte development and T cell lymphomagenesis. (1990) (35)
Repertoires of antigen receptors in Tdt congenitally deficient mice. (1996) (35)
Mechanisms that control antigen receptor variable region gene assembly. (1994) (34)
Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions (2010) (34)
Human Ig knockin mice to study the development and regulation of HIV‐1 broadly neutralizing antibodies (2017) (34)
4 – Organization and Expression of the Mammalian Heavy-Chain Variable-Region Locus (1989) (34)
Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development (2016) (33)
Expression of I mu-C gamma hybrid germline transcripts subsequent to immunoglobulin heavy chain class switching. (1994) (33)
Transcriptional down-regulation of N-myc expression during B-cell development (1992) (33)
The absence of the transcription activator TFE3 impairs activation of B cells in vivo (1997) (32)
Promotion of V(D)J recombinational accessibility by the intronic Ek element: role of the κB motif (1995) (32)
Neural blastocyst complementation enables mouse forebrain organogenesis (2018) (31)
Ataxia Telangiectasia Mutated (ATM) Is Dispensable for Endonuclease I-SceI-induced Homologous Recombination in Mouse Embryonic Stem Cells* (2013) (31)
Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes (2014) (31)
Cdc42 Facilitates Invasion but Not the Actin-Based Motility of Shigella (2002) (31)
Expression of the immunoglobulin heavy-chain variable gene repertoire. (1987) (31)
Molecular Mechanisms of Immunological Self-Recognition (1993) (31)
Nuclear factors that mediate intrathymic signals are developmentally regulated (1994) (30)
Evolution of immunoglobulin genes: VH families in the amphibian Xenopus. (1989) (30)
Frequency of VH-gene utilization in human EBV-transformed B-cell lines: the most JH-proximal VH segment encodes autoantibodies. (1989) (29)
Molecular biology of B cells (2015) (29)
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. (2007) (29)
Abnormalities of Thymic Stroma may Contribute to Immune Dysregulation in Murine Models of Leaky Severe Combined Immunodeficiency (2011) (28)
Activities involved in V(D)J recombination. (1992) (28)
T cell receptor DJ but not VDJ rearrangement within a recombination substrate introduced into a pre-B cell line. (1989) (27)
Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay (2018) (27)
CD40 expression and function in murine B cell ontogeny. (1996) (27)
Chromosomal location targets different MYC family gene members for oncogenic translocations (2009) (27)
Ectopic expression of RAD 52 and dn 53 BP 1 improves homology-directed repair during CRISPR – Cas 9 genome editing (2017) (27)
Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas (2013) (27)
Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2 (2013) (26)
Genomic organization and chromosomal localization of the mouse Bp3 gene, a member of the CD38/ADP-ribosyl cyclase family (1996) (26)
Diversity of immunoglobulin heavy chain gene segment rearrangement in B lymphoblastoid cell lines from X‐linked agammaglobulinemia patients (1991) (26)
RAG-2-Deficient Blastocyst Complementation (1994) (26)
Elucidation of a downstream boundary of the 3' IgH regulatory region. (2003) (26)
Structure and expression of human germline VH transcripts (1991) (26)
Productive Coupling of Accessible Vβ14 Segments and DJβ Complexes Determines the Frequency of Vβ14 Rearrangement1 (2008) (25)
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4 (2013) (25)
The Eδ enhancer controls the generation of CD4−CD8− αβTCR-expressing T cells that can give rise to different lineages of αβ T cells (2006) (25)
Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region (2016) (24)
Localized DNA Demethylation at Recombination Intermediates during Immunoglobulin Heavy Chain Gene Assembly (2013) (24)
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70. (2017) (24)
The cytoskeleton in lymphocyte signaling. (2000) (24)
Chromosomal location of N-myc and L-myc genes in the mouse. (1989) (24)
Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. (2003) (24)
Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. (2021) (23)
The Function of AID in Somatic Mutation and Class Switch Recombination (2002) (23)
Regulation of activation induced deaminase via phosphorylation. (2007) (23)
Immune checkpoint modulation enhances HIV-1 antibody induction (2020) (22)
Commitment of Immature CD4+8+ Thymocytes to the CD4 Lineage Requires CD3 Signaling but Does Not Require Expression of Clonotypic T Cell Receptor (TCR) Chains (1997) (22)
The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis. (2000) (22)
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair (2004) (21)
Human heavy chain variable region gene diversity, organization, and expression. (1990) (21)
Essential role for Vav1 in activation, but not development, of γδ T cells (2003) (21)
The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene. (1996) (21)
Vav 1 / 2 / 3-null mice define an essential role for vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells (2003) (20)
Amplification of IMR-32 clones 8, G21, and N-myc in human neuroblastoma xenografts. (1987) (20)
Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. (2006) (20)
Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations. (2008) (20)
The role of chromatin loop extrusion in antibody diversification (2022) (19)
Differential expression of myc-family genes during development: normal and deregulated N-myc expression in transgenic mice. (1988) (19)
CD3 epsilon and CD3 zeta cytoplasmic domains can independently generate signals for T cell development and function. (1995) (19)
A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity. (1990) (19)
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus (2007) (19)
Mitogen and il 4 regulated expression of germline immunoglobulin gamma 2b transcripts evidence for directed heavy chain class switching (1988) (19)
RAB 22 and RAB 163 y mouse BRCA 2 : Proteins that specifically interact with the RAD 51 protein (1997) (19)
The molecular events in heavy chain class-switching. (1989) (19)
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation. (2009) (19)
Mechanisms That Can Promote Peripheral B-cell Lymphoma in ATM-Deficient Mice (2014) (18)
Generation of normal lymphocytes derived from N-myc-deficient embryonic stem cells. (1995) (18)
Truncated immunoglobulin Dmu causes incomplete developmental progression of RAG-deficient pro-B cells. (2002) (18)
Antibody response elicited by T-dependent and T-independent antigens in gene targeted kappa-deficient mice. (1994) (17)
Receptor revision in T cells: an open question? (2004) (17)
Potential regulatory elements for germline transcription in or near murine Sgamma1. (1998) (17)
Cloning and Functional Characterization of the Early-Lymphocyte-Specific Pb99 Gene (2000) (16)
Functional homology between N-myc and c-myc in murine plasmacytomagenesis: plasmacytoma development in N-myc transgenic mice. (1992) (16)
Developmental regulation of TCR delta locus accessibility and expression by the TCR delta enhancer. (1999) (16)
Assembled DJβ Complexes Influence TCRβ Chain Selection and Peripheral Vβ Repertoire1 (2009) (16)
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination (2018) (16)
Post-translational regulation of activation-induced cytidine deaminase (2009) (16)
An Antibody from Single Human VH-rearranging Mouse Neutralizes All SARS-CoV-2 Variants Through BA.5 by Inhibiting Membrane Fusion (2022) (16)
T Cell Costimulation through CD28 Depends on Induction of the Bcl-xγ Isoform (2002) (15)
Mechanism of endogenous myc gene down-regulation in E mu-N-myc tumors (1991) (15)
Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells (2012) (15)
Sγ3 switch sequences function in place of endogenous Sγ1 to mediate antibody class switching (2008) (15)
Analysis of Mice Lacking DNaseI Hypersensitive Sites at the 5′ End of the IgH Locus (2010) (14)
Comparison of RAG gene expression in normal and transformed precursor lymphocytes. (1993) (14)
Ku70 suppresses alternative end joining in G1-arrested progenitor B cells (2019) (14)
Gene expression in renal growth and regrowth. (1988) (14)
The variable region gene assembly mechanism (1995) (14)
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies (2022) (14)
Intact Antiinfluenza Virus Immune Response in Targeted κ-Deficient Mice (1994) (14)
T cell receptor (TCR) alpha/delta locus enhancer identity and position are critical for the assembly of TCR delta and alpha variable region genes. (2003) (13)
Differential utilization of T cell receptor TCRα/TCRδ locus variable region gene segments is mediated by accessibility (2009) (13)
Sequence and organization of the human T cell delta chain gene. (1988) (13)
Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency. (2015) (13)
Restriction of endogenous T cell antigen receptor β rearrangements to Vβ14 through selective recombination signal sequence modifications (2007) (13)
Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement. (2008) (13)
Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-x(gamma) expression after CD28-dependent costimulation. (2002) (12)
The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus. (1995) (12)
Vβ cluster sequences reduce the frequency of primary Vβ2 and Vβ14 rearrangements (2008) (12)
A YAC contig encompassing the XRCC5 (Ku80) DNA repair gene and complementation of defective cells by YAC protoplast fusion. (1995) (12)
Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination (2017) (12)
IL-2 receptor alpha chain expression during early B lymphocyte differentiation. (1994) (12)
Control of Recombination Events During Lymphocyte Differentiation: Heavy Chain Variable Region Gene Assembly and Heavy Chain Class Switching a (1988) (11)
PROBES FOR SPECIFIC mRNAS BY SUBTRACTIVE HYBRIDIZATION: ANOMALOUS EXPRESSION OF IMMUNOGLOBULIN GENES1 (1979) (11)
An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments (2016) (11)
Immunology: RNA editing meets DNA shuffling (2000) (11)
Structure and expression of canary myc family genes (1991) (11)
Immunology: Exclusive immunoglobulin genes (1984) (10)
Germline transcription and recombination of a murine VDJmudeltagamma1 transgene. (1998) (10)
Enteropathogenic Escherichia coli and Vaccinia Virus Do Not Require the Family of WASP-Interacting Proteins for Pathogen-Induced Actin Assembly (2012) (10)
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons (2021) (10)
Structure of the gamma/delta T cell receptor of a human thymocyte clone (1988) (10)
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning (2020) (10)
Reconstruction of an immune system. (1988) (10)
Genome architecture and expression. (2013) (9)
Potential regulatory elements for germline transcription in or near murine S γ 1 (1998) (9)
Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer (2017) (9)
High frequency of myelomonocytic tumors in aging E mu L-myc transgenic mice (1992) (9)
Identification of the XRCC4 gene: complementation of the DSBR and V(D)J recombination defects of XR-1 cells. (1996) (9)
Essential role for Vav1 in activation, but not development, of gammadelta T cells. (2003) (9)
Promotion of V(D)J recombinational accessibility by the intronic E kappa element: role of the kappa B motif. (1995) (8)
mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice (2022) (8)
Physiological role of the 3′IgH CBEs super-anchor in antibody class switching (2021) (8)
Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture (2019) (8)
DNA recombination in the brain? (1991) (8)
Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences. (2021) (7)
T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. (2002) (7)
Parp3 promotes long-range end joining in murine cells (2018) (7)
The aging associated gene SIRT-1 regulates osteoclast formation and bone mass in vivo (2007) (7)
N‐myconcogene expression in histopathologically unrelated bilateral pediatric renal tumors (1988) (7)
Antibody diversity: New mechanism revealed (1986) (7)
Structural principles of B cell antigen receptor assembly (2022) (6)
Molecular biology: Case of mistaken identity (2004) (6)
Physiological role of the 3’IgH CBEs super-anchor in antibody class switching (2020) (6)
Regulation of immunoglobulin variable-region gene assembly. (1986) (6)
Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications. (2007) (6)
Direct analysis of brain phenotypes via neural blastocyst complementation (2018) (5)
Reprint of "Functional overlaps between XLF and the ATM-dependent DNA double strand break response". (2014) (5)
Circular T-cell receptor gene recombination products (1987) (5)
Myc family genes: a dispersed multi-gene family. (1986) (5)
NHEJ and Other Repair Factors in V(D)J Recombination (2016) (5)
Germline transcription and recombination of a murine VDJ μ δγ 1 transgene (1998) (5)
V(D)J recombinational accessibility—heading in the opposite direction? (2004) (5)
Complexity of the immunoglobulin light chain Vκ1 gene family in the New Zealand Black mouse (1991) (5)
Molecular cloning of a human immunoglobulin heavy chain variable (V H ) region with anti-myelin-associated glycoprotein activity (1990) (5)
Exclusive immunoglobulin genes. (1984) (5)
Control of immunoglobulin heavy chain constant region gene expression. (1991) (5)
PAIRing for distal Igh locus V(D)J recombination. (2011) (5)
Regulation of immunoglobulin variable region gene assembly: Development of the primary antibody repertoire (1986) (4)
INTRACELLULAR NAD LEVELS REGULATE TNF-α PROTEIN SYNTHESIS IN A SIRTUIN-DEPENDENT MANNER (2010) (4)
Aid for immunoglobulin diversity (2007) (4)
Structure and Expression of Human Germline (2003) (4)
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models (2020) (4)
Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells (2011) (4)
Intact antiinfluenza virus immune response in targeted kappa-deficient mice. (1994) (4)
Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism (2022) (4)
Novel antibody switching defects in human patients. (2003) (4)
Parp3 promotes long-range end-joining in murine cells (2018) (3)
V b cluster sequences reduce the frequency of primary V b 2 and V b 14 rearrangements (2008) (3)
Making antigen-receptor genes (1989) (3)
A Rapid Embryonic Stem Cell–Based Mouse Model for B-cell Lymphomas Driven by Epstein–Barr Virus Protein LMP1 (2015) (3)
Assembly of Productive T Cell Receptor (cid:100) Variable Region Genes Exhibits Allelic Inclusion (1998) (3)
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination (2022) (3)
that can give rise to diff erent lineages of αβ T cells (2006) (3)
Generation of antigen receptor diversity (1997) (2)
Expression of Cloned Immunoglobulin Genes (1985) (2)
An in vivo method for diversifying the functions of therapeutic antibodies (2020) (2)
PI3Kdelta Inhibitors Increase Genomic Instability By Upregulating Aid Expression (2015) (2)
Structure and expression of the human and mouse T 4 genes (2003) (2)
Essential role for Vav 1 in activation , but not development , of gd T cells (2003) (2)
Mechanisms of Lymphocyte Activation and Immune Regulation XI (2007) (2)
Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models (2020) (2)
C‐terminal deletion‐induced condensation sequesters AID from IgH targets in immunodeficiency (2022) (2)
Advances in Immunology : Volume 118 (2013) (2)
Molecular cloning of a human immunoglobulin heavy chain variable (VH) region with anti-myelin-associated glycoprotein activity (1990) (1)
Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination (2020) (1)
Inflammatory bowel disease in IL-2 deficient mice requires T, but not B lymphocytes (1995) (1)
Organization and Expression of Human VH Genes (1990) (1)
A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity (1990) (1)
Complexity of the immunoglobulin light chain V kappa 1 gene family in the New Zealand black mouse. (1991) (1)
Defects of B Cell Tolerance and Expansion of Immunoglobulin Secreting Cells in Rag-dependent Immunodeficiency (2010) (1)
Gene Expression During Post Natal and Compensatory Renal Growth (1987) (1)
B Cell Differentiation: Development of Antibody Repertoires (1989) (1)
Regulation of the Assembly and Expression of Immunoglobulin Genes: Variable Region Assembly and Heavy Chain Class Switching (1986) (1)
The aging associated gene SIRT-1 controls bone mass in vivo through osteoblast and osteoclast regulation (2008) (1)
Anniversary Note – Celebrating 25 years of Publication (2013) (1)
Activity of the myc-family of nuclear oncogenes in normal and malignant cells (1989) (1)
C D 5 and Immunoglobulin V Gene Expression in B-Cell Lymphomas and Chronic Lymphocytic Leukemia (2003) (1)
Vaccination Induces Maturation of Diverse Unmutated VRC01-Class Precursors to HIV-1 Broadly Neutralizing Antibodies in an Ig-Humanized Mouse Model (2020) (1)
Correlation between the occurrence of lupus nephritis, anti‐erythrocyte autoantibodies and Vx haplotype in NZB × 129/J and NZB × SM/J recombinant inbred murine strains (1991) (1)
An essential role for N-WASP, but not Cdc42, in EPEC induced pedestal formation (2001) (0)
OR.1. Hypomorphic Rag1 and Lig4 Mutants are a Model for Human Leaky SCID (2008) (0)
Frequency of VH gene utilization in human B cell populations: Correlations with autoantibody specificities (1989) (0)
Erratum: Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress (Cell Metabolism) (2005) vol. 2 (67-76)) (2006) (0)
Abstract A033: Mechanisms that mediate intralocus and interlocus regulation of V(D)J recombination at immunoglobulin light chain loci (2016) (0)
Repertoire / Diversity (T and B) (SY3-3) Chairpersons: Masamichi Muramatsu, Kristin Hogquist (2010) (0)
Immunology: making antigen-receptor genes. (1989) (0)
Abstract B087: Revealing antibody repertoires and RAG tracking by linear amplification mediated-high-throughput genome-wide translocation sequencing (2016) (0)
Class Switching in B Cells Lacking 3 (cid:57) Immunoglobulin Heavy Chain Enhancers (1998) (0)
568. Transient Manipulation of DNA Damage Repair Pathway Choice Improves Homology-Directed Repair During CRISPR/Cas9-Mediated Genome Editing (2016) (0)
The role of Cdc42 in the invasion and the actin-based motility of Shigella flexneri (2001) (0)
The BCL11B Tumor Suppressor Is Mutated In Human T-Cell Acute Lymphoblastic Leukemia (2010) (0)
AnOncogenic Role for Alte rnative NFk B Signaling in DLBCLRevealed uponDeregulatedBCL 6 Expression Graphical Abstract Highlights (0)
Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing (2017) (0)
Guiding a mutator in antibody diversification (2018) (0)
Immunoglobulin enhancers increase RNA polymerase 2 stalling at somatic hypermutation target sequences (2021) (0)
PI 3-KINASE KNOCKOUT MICE: ROLE OF p85α IN B CELL DEVELOPMENT AND PROLIFERATION (1999) (0)
Lymphoid VDJ Recombinase Activity: Development of a Novel Fluorescence-Based Assay System (1989) (0)
Abnormal development c lymphocytes in Atm mut (2016) (0)
Evaluation of a Novel Missense Activation-Induced Deaminase AID Mutation in a Child with Hyper IgM Syndrome: Is it a Pathogenic Mutation? (2014) (0)
Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors (2018) (0)
Coordinate regulation of expression and lymphokine inducibility of a beta 2 and e beta 2 messenger rna (1990) (0)
Resistance to Acute Viral Infection Mediated by CD1-Reactive T Cells (2000) (0)
The Use of Targeted Mutations in ES Cells to Create Novel Immunodeficient Mouse Models (1994) (0)
subtypes of T-cell acute lymphoblastic leukemia tumor suppressor is mutated across the major molecular BCL11B The (2013) (0)
Michael Neuberger (1953-2013). (2013) (0)
noncanonical DNA sequences. Binding of myc proteins to canonical and (2013) (0)
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors (2018) (0)
Abstract A180: Topologically associated domains genome-wide restrict the off-target activity of recombination activating gene 1/2 endonuclease (2016) (0)
Abstract B37: PARP inhibitor olaparib induces genomic instability in normal mammalian cells (2017) (0)
Unique and divergent roles for WASP family members in Salmonella entry (2003) (0)
growthcontrols endothelial angiogenic functions during vascular (2007) (0)
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies (2023) (0)
Binding ofMycProteins toCanonical andNoncanonical DNA Sequences (1993) (0)
Sorting, cloning and analysis of specific human chromosomes (1984) (0)
rearrangements due to a hypomorphic RAG1 mutation Leaky severe combined immunodeficiency and aberrant DNA (2009) (0)
Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction (2022) (0)
Gene Therapy Gene Therapy for Wiskott Aldrich Syndrome-Rescue of T-Cell Signaling and Amelioration of Colitis upon Transplantation of Retrovirally Transduced Hematopoietic Stem Cells in Mice (2002) (0)
Immunogenicity of a germline-targeting nanoparticle in knock-in mice expressing human B cell receptors of the HIV gp41 neutralizing antibody, DH511 (2022) (0)
BCR selection and affinity maturation in Peyer’s patch germinal centres (2020) (0)
Contribution of the IGCR1 regulatory element and the 3’Igh CBEs to Regulation of Igh V(D)J Recombination (2023) (0)
Physiological V(D)J Recombination is Mediated by RAG Scanning of Loop-extruded Chromatin (2019) (0)
Comprar Advances In Immunology, Vol. 106 | Alt, Frederick W. | 9780123813046 | Academic Press (2010) (0)
TrieDedup: A fast trie-based deduplication algorithm to handle ambiguous bases in high-throughput sequencing (2022) (0)
Influence of i.mmunoglobulin heavy- and light-chain expression on B-cell differentiation (2007) (0)
Involvement of Bruton’s Tyrosine Kinase in Fc (cid:101) RI-dependent Mast Cell Degranulation and Cytokine Production (1998) (0)
Pillars Article: Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes. Science. 1993. 259: 822-825. (2019) (0)
Generally expressed gene products involved in VDJ recombination and DNA repair (1998) (0)
Abstract 3660: Signal-Responsive Repression of Notch1 Signaling by the Sirt1 Deacetylase Regulates Sprouting Angiogenesis (2008) (0)
Immune checkpoint modulation enhances HIV-1 antibody induction (2020) (0)
Abstract 286: Sirt1 Controls Endothelial Angiogenic Functions During Vascular Growth And Maturation (2007) (0)
Abstract B171: Elucidating the mechanism of RAG tracking and its impacts on V(D)J recombination (2019) (0)
Pillars Article: A Functional T3 Molecule Associated with a Novel Heterodimer on the Surface of Immature Human Thymocytes. Nature. 1986. 322: 179-181. (2016) (0)
Differentiation antigens associated with the function of alloreactive T lymphocytes. (1987) (0)
Leaky SCID and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation (2008) (0)
Identification ofa Conserved Lipopolysaccharide-Plus-Interleu kin-4- Responsive Element Located atthePromoter of GermLineETranscripts (1991) (0)
The Mechanism of IgH Class Switch Recombination (2015) (0)
Abstract B099: Elucidating the mechanisms that underpin RAG chromatin scanning in V(D)J recombination at antigen receptor gene loci (2019) (0)
Isolation ofcoordinately regulated genesthatareexpressed in discrete stages ofB-cell development (1990) (0)
Mutational analyses of lymphocyte differentiation. (1992) (0)
Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination (2022) (0)
From gene amplification to V(D)J recombination and back: A personal account of my early years in B cell biology (2007) (0)
The fundamental role of chromatin loop extrusion in physiological V(D)J recombination (2019) (0)
Fluorescence-Activated Flow Sorting of Metaphase Chromosomes Isolation of Amplified DNA Sequences from IMR-32 Human Neuroblastoma Cells: Facilitation by (2006) (0)
Fundamental roles of chromatin loop extrusion in antibody class switching (2019) (0)
The actin-based motility of Shigella flexneri requires N-WASP (2000) (0)
Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors (2022) (0)
DNA melting initiates the RAG catalytic pathway (2018) (0)
Neural blastocyst complementation enables mouse forebrain organogenesis (2018) (0)
Loop extrusion mediates physiological Igh locus contraction for RAG scanning (2021) (0)
TCL1 sensitizes B cells to transformation by a pathway requiring germinal center passage and induction of genomic instability (2006) (0)
Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation (2023) (0)
Structure, function and regulation of BP-3, a member of the CD38/ADP-ribosyl cyclase family (1996) (0)
T cell receptor B chain rearrangements in human suppressor T lymphocytes. (1987) (0)
T Cell Responses in Calc ineur in AoL-deficient Mice (2003) (0)
AID Recognizes Structure d DNA for Class Switch Recombination Graphical (2017) (0)
Cloning and Functional Characterization of the Early-Lymphocyte-Speciﬁc Pb99 Gene (2000) (0)
F.121. B Cell-mediated Autoimmunity in Hypomorphic rag1 and lig4 Mouse Mutants as Models for Human Leaky SCID (2009) (0)
Early B Lineage Cells Display Class Switch Preference To Ige (2011) (0)
Mechanisms of Recurrent Chromosomal Translocations (2015) (0)
Guiding a mutator in antibody diversification (2018) (0)

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