Frederick Samuel Kaplan
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Frederick Samuel Kaplan's Degrees
- Doctorate Medicine University of Pennsylvania
- PhD Molecular Biology University of Pennsylvania
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(Suggest an Edit or Addition)Frederick Samuel Kaplan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva (2006) (1053)
- Bone Formation and Inflammation in Cardiac Valves (2001) (1032)
- Conversion of vascular endothelial cells into multipotent stem-like cells (2010) (565)
- Prevention and management of osteoporosis. (1995) (478)
- Treatment of Osteoporosis: Are Physicians Missing an Opportunity?*† (2000) (384)
- Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1 (2009) (362)
- The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients. (1993) (314)
- Identification of progenitor cells that contribute to heterotopic skeletogenesis. (2009) (285)
- Paternally inherited inactivating mutations of the GNAS1 gene in progressive osseous heteroplasia. (2002) (271)
- Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects (2011) (238)
- Osteoporosis: Definition and Clinical Presentation (1997) (236)
- Inherited human diseases of heterotopic bone formation (2010) (229)
- Iatrogenic Harm Caused by Diagnostic Errors in Fibrodysplasia Ossificans Progressiva (2005) (217)
- The histopathology of fibrodysplasia ossificans progressiva. An endochondral process. (1993) (216)
- The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. (2009) (203)
- Severe Osteoporosis in Men (1995) (202)
- Progressive Osseous Heteroplasia (1998) (201)
- Constitutively Activated ALK2 and Increased SMAD1/5 Cooperatively Induce Bone Morphogenetic Protein Signaling in Fibrodysplasia Ossificans Progressiva* (2009) (179)
- Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification (2013) (173)
- Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva. (2010) (160)
- Early Diagnosis of Fibrodysplasia Ossificans Progressiva (2008) (159)
- An Acvr1 R206H knock‐in mouse has fibrodysplasia ossificans progressiva (2012) (155)
- Heparan Sulfate Proteoglycans (HSPGs) Modulate BMP2 Osteogenic Bioactivity in C2C12 Cells* (2007) (149)
- Diagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS‐based heterotopic ossification (2008) (149)
- In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. (2003) (148)
- Progressive osseous heteroplasia: a distinct developmental disorder of heterotopic ossification. Two new case reports and follow-up of three previously reported cases. (1994) (146)
- THE MEDICAL MANAGEMENT OF FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: CURRENT TREATMENT CONSIDERATIONS (2011) (144)
- The Natural History of Flare‐Ups in Fibrodysplasia Ossificans Progressiva (FOP): A Comprehensive Global Assessment (2016) (143)
- Dysregulated BMP Signaling and Enhanced Osteogenic Differentiation of Connective Tissue Progenitor Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP) (2007) (139)
- Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons. (2013) (132)
- Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1R206H Fibrodysplasia Ossificans Progressiva (FOP) Mutation (2016) (122)
- Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP). (2008) (118)
- Hematopoietic stem-cell contribution to ectopic skeletogenesis. (2007) (117)
- Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family. (1993) (113)
- The phenotype of fibrodysplasia ossificans progressiva (2005) (112)
- Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis (2012) (111)
- Deficiency of the α‐Subunit of the Stimulatory G Protein and Severe Extraskeletal Ossification (2000) (110)
- Estrogen receptors in bone in a patient with polyostotic fibrous dysplasia (McCune-Albright syndrome). (1988) (110)
- Age- and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. (1994) (107)
- Fibrodysplasia Ossificans Progressiva (FOP), a Disorder of Ectopic Osteogenesis, Misregulates Cell Surface Expression and Trafficking of BMPRIA (2005) (104)
- Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva. (1995) (104)
- Paradoxical Effects of Statins on Aortic Valve Myofibroblasts and Osteoblasts: Implications for End-Stage Valvular Heart Disease (2005) (103)
- Substance P signaling mediates BMP‐dependent heterotopic ossification (2011) (100)
- Severe restriction in jaw movement after routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva. (1996) (99)
- Dysregulation of the BMP‐p38 MAPK Signaling Pathway in Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP) (2006) (98)
- Paresis of a Bone Morphogenetic Protein-Antagonist Response in a Genetic Disorder of Heterotopic Skeletogenesis (2003) (94)
- Alk2 Regulates Early Chondrogenic Fate in Fibrodysplasia Ossificans Progressiva Heterotopic Endochondral Ossification (2014) (90)
- Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling (2016) (90)
- Functional Modeling of the ACVR1 (R206H) Mutation in FOP (2007) (87)
- Heterotopic Ossification: Two Rare Forms and What They Can Teach Us (1994) (86)
- Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1R206H Mouse Model of Fibrodysplasia Ossificans Progressiva (2018) (85)
- Developmental Anomalies of the Cervical Spine in Patients With Fibrodysplasia Ossificans Progressiva Are Distinctly Different From Those in Patients With Klippel-Feil Syndrome: Clues From the BMP Signaling Pathway (2005) (81)
- GNAS1 Mutation and Cbfa1 Misexpression in a Child with Severe Congenital Platelike Osteoma Cutis (2000) (80)
- Thoracic insufficiency syndrome in patients with fibrodysplasia ossificans progressiva (2005) (75)
- Influenza-like Viral Illnesses and Flare-ups of Fibrodysplasia Ossificans Progressiva (2004) (75)
- Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva. (2008) (73)
- Heterozygous inactivation of Gnas in adipose‐derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification (2011) (73)
- Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP) (2008) (71)
- Heterotopic Ossification (2004) (69)
- Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva. (1994) (68)
- The genetics of fibrodysplasia ossificans progressiva (2005) (68)
- Progressive osseous heteroplasia: diagnosis, treatment, and prognosis (2015) (67)
- Pulmonary and cardiac function in advanced fibrodysplasia ossificans progressiva. (1998) (67)
- In vitro Analyses of the Dysregulated R206H ALK2 Kinase-FKBP12 Interaction Associated with Heterotopic Ossification in FOP (2011) (65)
- The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling. (2009) (62)
- Idiopathic familial acroosteolysis: histomorphometric study of bone and literature review of the Hajdu-Cheney syndrome. (1986) (62)
- Hurler syndrome with special reference to histologic abnormalities of the growth plate. (1991) (60)
- Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa‐1: clues to a vascular origin of heterotopic ossification? (2003) (60)
- Treatment considerations for the management of fibrodysplasia ossificans progressiva (2005) (59)
- Spinal deformity in patients who have fibrodysplasia ossificans progressiva. (1994) (59)
- Fibrodysplasia ossificans progressiva: A clue from the fly? (1990) (58)
- The Immunological Contribution to Heterotopic Ossification Disorders (2015) (58)
- Dysregulation of the BMP‐4 Signaling Pathway in Fibrodysplasia Ossificans Progressiva (2006) (57)
- The phenotype and genotype of fibrodysplasia ossificans progressiva in China: a report of 72 cases. (2013) (57)
- Osteon morphometry in females with femoral neck fractures. (1992) (56)
- Granting immunity to FOP and catching heterotopic ossification in the Act. (2016) (56)
- Osteopetrorickets. The paradox of plenty. Pathophysiology and treatment. (1993) (53)
- A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton (2007) (53)
- Catastrophic falls in patients who have fibrodysplasia ossificans progressiva. (1998) (52)
- Regional migratory osteoporosis. A case report and review of the literature. (1990) (51)
- The face signature of fibrodysplasia ossificans progressiva (2012) (50)
- Deficiency of the alpha-subunit of the stimulatory G protein and severe extraskeletal ossification. (2000) (50)
- Bone Morphogenetic Protein-4 Regulation in Fibrodysplasia Ossificans Progressiva (2003) (50)
- Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway (2005) (49)
- CNS demyelination in fibrodysplasia ossificans progressiva (2012) (47)
- Submandibular Swelling in Patients with Fibrodysplasia Ossificans Progressiva (1996) (45)
- Neurological symptoms in individuals with fibrodysplasia ossificans progressiva (2012) (43)
- Lamin B 1 duplications cause autosomal dominant leukodystrophy (2007) (43)
- Skin and bones. (1996) (41)
- Three pairs of monozygotic twins with fibrodysplasia ossificans progressiva (2005) (41)
- Enhanced survival of rat neonatal cerebral cortical neurons at subatmospheric oxygen tensions in vitro (1986) (40)
- Osteoporosis and hip fracture in a young woman with anorexia nervosa. (1986) (39)
- Treatment of castration-induced osteoporosis by a capacitively coupled electrical signal in rat vertebrae. (1989) (39)
- Treatment of patients who have fibrodysplasia ossificans progressiva with isotretinoin. (1998) (38)
- ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant. (2014) (38)
- Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes (2019) (38)
- Diabetes-like renal glomerular disease in Fanconi-Bickel syndrome (1995) (35)
- Metatropic dwarfism. Uncoupling of endochondral and perichondral growth. (1987) (35)
- Vascular ossification: Pathology, mechanisms, and clinical implications. (2017) (35)
- A cumulative analogue joint involvement scale (CAJIS) for fibrodysplasia ossificans progressiva (FOP). (2017) (35)
- Limb Swelling in Patients Who Have Fibrodysplasia Ossificans Progressiva (1997) (35)
- From mysteries to medicines: drug development for fibrodysplasia ossificans progressiva (2013) (35)
- Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis (2011) (34)
- Osteomalacia and osteitis fibrosa in a man ingesting aluminum hydroxide antacid. (1984) (34)
- Morphogen receptor genes and metamorphogenes: skeleton keys to metamorphosis. (2007) (34)
- Progressive osseous heteroplasia. Report of a family. (1998) (34)
- Hard targets for a second skeleton: therapeutic horizons for fibrodysplasia ossificans progressiva (FOP) (2017) (33)
- Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases. (2017) (33)
- Role of Altered Signal Transduction in Heterotopic Ossification and Fibrodysplasia Ossificans Progressiva (2011) (32)
- Oral and dental health care and anesthesia for persons with fibrodysplasia ossificans progressiva (2005) (32)
- Multi‐system involvement in a severe variant of fibrodysplasia ossificans progressiva (ACVR1 c.772G>A; R258G): A report of two patients (2015) (31)
- Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia. (2013) (31)
- THE TWELFTH ANNUAL REPORT (2003) (31)
- Proximal femoral focal deficiency. Evidence for a defect in proliferation and maturation of chondrocytes. (1989) (31)
- Progressive osseous heteroplasia-like heterotopic ossification in a male infant with pseudohypoparathyroidism type Ia: a case report. (2007) (31)
- Conductive Hearing Loss in Individuals with Fibrodysplasia Ossificans Progressiva (1999) (30)
- Conductive hearing loss in individuals with fibrodysplasia ossificans progressiva. (1999) (30)
- Fibrodysplasia ossificans progressiva (FOP): watch the great toes! (2010) (30)
- Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP). (2017) (29)
- Paternally Inherited Gsα Mutation Impairs Adipogenesis and Potentiates a Lean Phenotype In Vivo (2012) (28)
- HSPG modulation of BMP signaling in fibrodysplasia ossificans progressiva cells (2007) (28)
- The effect of anorexia nervosa on bone morphometry in young women. (1985) (28)
- Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP). (2017) (28)
- Paget's Disease of Bone: Pathophysiology, Diagnosis, and Management (1995) (27)
- The role of morphogens in endochondral ossification (1992) (27)
- Progressive Osseous Heteroplasia in Male Patients: Two New Case Reports (1995) (27)
- Successful treatment of infantile malignant osteopetrosis by bone-marrow transplantation. A case report. (1988) (27)
- Surgical management of paget's disease (1999) (27)
- Fibrodysplasia ossificans progressiva: report of a case with guidelines for pediatric dental and anesthetic management. (1996) (25)
- General Anesthesia for Dental Procedures in Patients with Fibrodysplasia Ossificans Progressiva: A Review of 42 Cases in 30 Patients (2014) (25)
- Progressive osseous heteroplasia in the face of a child (2003) (24)
- The skeleton in the closet. (2013) (23)
- When one skeleton is enough: approaches and strategies for the treatment of fibrodysplasia ossificans progressiva (FOP). (2008) (23)
- Differential expression of bone and cartilage related genes in fibrodysplasia ossificans progressiva, myositis ossificans traumatica, and osteogenic sarcoma. (1998) (23)
- Chin-on-chest deformity in patients with fibrodysplasia ossificans progressiva. A case series. (2009) (22)
- Classic and Atypical FOP Phenotypes are Caused by Mutations in the BMP Type I Receptor ACVR 1 (2011) (22)
- Severe orthopaedic complications of Paget's disease. (1999) (22)
- Heparan Sulfate Proteoglycans ( HSPGs ) Modulate BMP 2 Osteogenic Bioactivity in C 2 C 12 Cells * (2006) (22)
- Paget's disease of bone: orthopedic complications. (1994) (22)
- Traumatic Fractures of Heterotopic Bone in Patients Who Have Fibrodysplasia Ossificans Progressiva: A Report of 2 Cases (1994) (22)
- Derailing heterotopic ossification and RARing to go (2011) (21)
- Morphogen Receptor Genes and Metamorphogenes (2007) (21)
- Clinical staging of Fibrodysplasia Ossificans Progressiva (FOP). (2017) (21)
- Transient infantile osteopetrosis. (1991) (20)
- Pseudomalignant heterotopic ossification : Differential diagnosis and report of two cases (1998) (20)
- The musculoskeletal manifestations of progeria. A literature review. (1988) (20)
- Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways (2017) (20)
- Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization (2021) (19)
- Lumbar puncture and surgical intervention in a child with undiagnosed fibrodysplasia ossificans progressiva. (2008) (19)
- Estrogen receptors in fracture healing. (1992) (19)
- Over‐expression of BMP4 and BMP5 in a child with axial skeletal malformations and heterotopic ossification: A new syndrome (2007) (19)
- Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable. (2017) (19)
- Acute and chronic rapamycin use in patients with Fibrodysplasia Ossificans Progressiva: A report of two cases. (2017) (18)
- Skeletal malformations and developmental arthropathy in individuals who have fibrodysplasia ossificans progressiva. (2019) (18)
- Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome (2020) (18)
- The FOP Connection Registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva. (2017) (18)
- Pseudomalignant heterotopic ossification. (1998) (18)
- The cluster phenomenon in patients who have multiple vertebral compression fractures. (1993) (17)
- Epidemiology of the Global Fibrodysplasia Ossificans Progressiva (FOP) Community (2020) (17)
- Investigations of activated ACVR1/ALK2, a bone morphogenetic protein type I receptor, that causes fibrodysplasia ossificans progressiva. (2010) (16)
- ECSIT links TLR and BMP signaling in FOP connective tissue progenitor cells. (2017) (15)
- Reported noggin mutations are PCR errors. (2002) (15)
- Bone densitometry observations of osteopetrosis in response to bone marrow transplantation. (1993) (15)
- Controlled study of renal osteodystrophy in patients undergoing dialysis. Improved response to continuous ambulatory peritoneal dialysis compared with hemodialysis. (1987) (14)
- Joint-specific risk of impaired function in fibrodysplasia ossificans progressiva (FOP). (2017) (14)
- Fibrodysplasia Ossificans Progressiva Why Do Some People Have Two Skeletons? (1997) (14)
- Body Mass and Fracture Risk: A Study of 330 Patients (1999) (14)
- Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva. (2017) (13)
- ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressiva. (2016) (13)
- Respiratory Complications of Metatropic Dwarfism (1985) (13)
- Fibrodysplasia Ossificans Progressiva (FOP): A Disorder of Osteochondrogenesis. (2020) (13)
- International physician survey on management of FOP: a modified Delphi study (2017) (13)
- Osteoporosis. Pathophysiology and prevention. (1987) (12)
- Animal models of fibrodysplasia ossificans progressiva (2005) (12)
- Skeletal response to immobilization in Paget's disease of bone: a case report. (1996) (12)
- Alkaline phosphatase production by periosteal cells at various oxygen tensions in vitro. (1990) (11)
- Quantitative computed tomography reflects vertebral fracture morbidity in osteopenic patients. (1989) (11)
- Fibrodysplasia Ossificans Progressiva: An Historical Perspective (2005) (11)
- A longitudinal study of metacarpal bone morphometry in anorexia nervosa. (1992) (11)
- Boning-up on aortic valve calcification. (2012) (10)
- Prevalence and risk factors for kidney stones in fibrodysplasia ossificans progressiva. (2018) (10)
- Acute unilateral hip pain in fibrodysplasia ossificans progressiva (FOP). (2017) (10)
- Corrigendum: A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva (2007) (10)
- Multiple pathologic fractures of the appendicular skeleton in a patient with Cushing's disease. (1987) (10)
- Longitudinal patient-reported mobility assessment in fibrodysplasia ossificans progressiva (FOP). (2017) (10)
- Fibrodysplasia ossificans progressiva and progressive osseous heteroplasia (2005) (10)
- Fibrodysplasia ossificans progressiva: Searching for the skeleton key (1996) (10)
- Severe Symptomatic Osteopenia in a Man With Pigmented Micronodular Adrenal Hyperplasia (1995) (9)
- Druggable targets, clinical trial design and proposed pharmacological management in fibrodysplasia ossificans progressiva (2020) (9)
- The congenital great toe malformation of fibrodysplasia ossificans progressiva? - A close call. (2017) (9)
- Answer: Marrow stem cell transplantation in fibrodysplasia ossificans progressiva. (2001) (9)
- Calcium homeostasis. (1990) (9)
- Treatment of Osteoporosis (2000) (9)
- Fibrodysplasia Ossificans Progressiva: Developmental Implications of a Novel Metamorphogene (2010) (9)
- Osteomalacia in a night nurse. (1986) (9)
- Paget's disease: Complications and controversies (1994) (9)
- The carniofacial phenotype of fibrodysplasia ossificans progressiva (2005) (8)
- A Bone Morphogenetic Protein Subfamily : Chromosomal Localization of Human Genes for BMP 5 , BMP 6 , and BMP 7 (2005) (8)
- Dysregulation of BMP4 receptor trafficking and signaling in fibrodysplasia ossificans progressiva (2005) (8)
- Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop (2021) (8)
- Pregnancy in fibrodysplasia ossificans progressiva (2012) (8)
- Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva (2020) (7)
- Perspective Progressive Osseous Heteroplasia (2000) (7)
- Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral ossification (HEO) in fibrodysplasia ossificans progressiva (FOP). (2017) (7)
- A case report of mesenteric heterotopic ossification: Histopathologic and genetic findings. (2018) (7)
- Osteomalacia as a very late manifestation of primary hyperparathyroidism. (1988) (7)
- Analog Method for Radiographic Assessment of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva. (2017) (7)
- Patient-Reported Physical Function Outcome Measure for Adults With Fibrodysplasia Ossificans Progressiva: Intelligent Test Design Based on Promis Item Banks (2015) (7)
- Skeletal dysplasia in perinatal lethal osteogenesis imperfecta. A complex disorder of endochondral and intramembranous ossification. (1993) (7)
- Severe soft tissue ossification in a southern right whale Eubalaena australis. (2012) (6)
- Ablation of Gsα signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance. (2017) (6)
- Paget's disease of bone: pathophysiology and diagnosis. (1993) (6)
- BMP‐1 Sublocalization on Human Chromosome 8: Molecular Anatomy and Orthopaedic Implications (1995) (6)
- Severe digital malformations in a rare variant of fibrodysplasia ossificans progressiva (2019) (6)
- The articular manifestations of Paget's disease of bone. A case report. (1992) (5)
- Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP). (2020) (5)
- Chapter 24 – Fibrodysplasia (Myositis) Ossificans Progressiva (2013) (5)
- Whole-body Computed Tomography Versus Dual Energy X‑ray Absorptiometry for Assessing Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva (2021) (5)
- The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study. (2022) (5)
- Dental complications of paget's disease: The need for hard facts about hard tissues (1993) (5)
- Clearance of Senescent Cells From Injured Muscle Abrogates Heterotopic Ossification in Mouse Models of Fibrodysplasia Ossificans Progressiva (2021) (4)
- Enchondroma in a patient with fibrodysplasia ossificans progressiva. (1993) (4)
- Focal fibronodular heterotopic ossification. A case report. (2007) (4)
- Maternal Genetic Skeletal Disorders: Lessons Learned From Cases of Maternal Osteogenesis Imperfecta and Fibrodysplasia Ossificans Progressiva (2015) (4)
- Orthopedic surgery considerations in Paget's disease of bone (2002) (4)
- Exoneration of NF-kappaB dysregulation in fibrodysplasia ossificans progressiva. (2003) (3)
- Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva. (2021) (3)
- Direct extracellular electrical stimulation influences density dependent aggregation of fetal rat cerebrocortical neurons in vitro (1988) (3)
- The Developmental Phenotype of the Great Toe in Fibrodysplasia Ossificans Progressiva (2020) (3)
- Surgery in Paget's Disease (1991) (3)
- Bone Formation and Osteoclast Remodeling in Calcified Cardiac Valves: A Clinical and Pathologic Analysis (1998) (3)
- Genetic Disorders of Heterotopic Ossification (2018) (3)
- Treatment of Patients Who Have Fibrodysplasia Ossificans Progressiva with 13-cis-Retinoic Acid (Isotretinoin) (1998) (3)
- Palovarotene inhibits the development of new heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) (2019) (3)
- Plasma‐Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States (2021) (3)
- Corrigendum: Conversion of vascular endothelial cells into multipotent stem-like cells (2011) (3)
- Orthopedic surgical forum: A novel idea? (1993) (2)
- Reply to: Macrophages Driving Heterotopic Ossification: Convergence of Genetically‐Driven and Trauma‐Driven Mechanisms (2018) (2)
- Functional Analysis of Alleged NOGGIN Mutation G92E Disproves Its Pathogenic Relevance (2012) (2)
- Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles (2022) (2)
- QUANTITATIVE ASSESSMENT OF TRABECULAR BONE MINERAL CONTENT AND ITS RELATIONSHIP TO THE RISK OF FRACTURE IN THE OSTEOPENIC PATIENT (1983) (2)
- Letters to the Editor: Bone Marrow Tranplantation in a Patient with Fibrodysplasia (2004) (2)
- Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes (2019) (2)
- The complex craniofacial signature of fibrodysplasia ossificans progressiva: Whose handwriting is it? (2012) (2)
- Cover Image, Volume 179A, Number 7, July 2019 (2019) (2)
- Activities of Dysregulated ALK2 Receptor Kinases Provide Insight Into the Protein Structural‐Functional Basis of Fibrodysplasia Ossificans Progressiva (2016) (2)
- Caregiver Support in Fibrodysplasia Ossificans Progressiva (2021) (2)
- ACVR 1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossi fi cans progressiva ☆ (2016) (2)
- Garetosmab Reduces Flare-ups in Patients With Fibrodysplasia Ossificans Progressiva (2021) (2)
- Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo‐Controlled, Double‐Blind Phase 2 Trial (2022) (2)
- Heterotopic Ossification in the Mesentery After Abdominal Surgery (2006) (2)
- The impact of fibrodysplasia ossificans progressiva (FOP) on patients and their family members: results from an international burden of illness survey (2022) (1)
- Book ReviewAlgodystrophy: Diagnosis and therapy of a frequent disease of the locomotor apparatus (1982) (1)
- An ACVR1R375P pathogenic variant in two families with mild fibrodysplasia ossificans progressiva (2021) (1)
- OR29-05 A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP): 12-Month Outcomes (2020) (1)
- Viewing FOP through rosi‐colored glasses (2010) (1)
- Exoneration of NF- B Dysregulation in Fibrodysplasia Ossificans Progressiva (2002) (1)
- Paget's disease of bone: Exploring the questions (1992) (1)
- Surgical and Radiological Management of Complicated Uterine Leiomyoma Aided by 3D Models in a Patient with Fibrodysplasia Ossificans Progressiva (2021) (1)
- The Fibrodysplasia Ossificans Progressiva Physical Function Questionnaire (FOP-PFQ): A patient-reported, disease-specific measure. (2022) (1)
- Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP) (2022) (1)
- A natural history study of fibrodysplasia ossificans progressiva (FOP): 12-month outcome results (2020) (1)
- Chapter 94. Fibrodysplasia (Myositis) Ossificans Progressiva (2009) (1)
- Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery (2022) (1)
- Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective (2022) (1)
- Abstracts from the First International Symposium on Fibrodsyplasia Progressive, September 25–26, 1991, Philadelphia, Pennsylvania (2004) (0)
- Hope for escape from a prison of bone: Cellular and molecular targets for fibrodysplasia ossificans progressiva (2018) (0)
- Garetosmab, an inhibitor of activin A, reduces heterotopic ossification and flare-ups in adults with fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial (2023) (0)
- Fibrodysplasia Ossificans Progressiva Early Mortality and Cardiorespiratory Failure in Patients with (2010) (0)
- Compartment Syndrome of the Thigh in a Patient with Fibrodysplasia Ossificans Progressiva (2020) (0)
- Glucocorticoid osteopenia. (1985) (0)
- 13 – Fibrous Dysplasia (1999) (0)
- ACVR1 and Fibrodysplasia Ossificans Progressiva (2016) (0)
- The effects of palovarotene in patients with fibrodysplasia ossificans progressiva: a plain language summary (2023) (0)
- SEQUENTIAL QUANTITATIVE COMPUTED TOMOGRAPHY OF THE LUMBAR SPINE IN THE EVALUATION OF BONE REMODELING FOLLOWING BONE MARROW TRANSPLANTATION FOR THE TREATMENT OF CONGENITAL MALIGNANT OSTEOPETROSIS (1985) (0)
- Nonclassic fibrodysplasia ossificans progressiva: A child from Angola with an ACVR1G328E variant (2021) (0)
- Extraskeletal Bone Formation (2012) (0)
- Estrogen Receptors in Bonein a Patient with Pol ycystic Fibrous Dysplasia(McCune-Albrig ht Syndrome) (1989) (0)
- Spontaneous resolution of a compartment syndrome. (1985) (0)
- Fibrodysplasia Ossificans Progressiva in Three Filipino Children (2020) (0)
- Fibrodysplasia Ossificans Progressiva and Pregnancy: A Case Series and Review of the Literature (2022) (0)
- General Anesthesia for Patients with Fibrodysplasia Ossificans Progressiva: A Review of 42 Cases (2010) (0)
- SUN-344 Patients with Fibrodysplasia Ossificans Progressiva Have an Increased Prevalence of Cardiac Conduction Abnormalities (2020) (0)
- P068 Abstract tin soldiers Global FOP patient search (2021) (0)
- Body mass and fracture risk: a study of 330 patients. 1999. (2003) (0)
- HG-59ACVR1-MUTANT DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs) ACQUIRE ABERRANT ACTIVIN-MEDIATED BMP PATHWAY ACTIVATION. (2016) (0)
- Fibrodysplasia ossificans progressiva: baseline characteristics of 101 subjects participating in a global, longitudinal, natural history study (2017) (0)
- Key to the kingdom: the challenge of rare diseases (2008) (0)
- “Your Pal, John” (1997) (0)
- The preakness fracture: a case report of a rare injury to the distal forearm. (1982) (0)
- Spatial patterns of heterotopic ossification in Fibrodysplasia Ossificans Progressiva correlate with anatomic temperature gradients. (2021) (0)
- Abstracts from the symposium on recent advances in Paget’s disease of bone and related bone diseases (1996) (0)
- BMP Signaling in Fibrodysplasia Ossificans Progressiva, a Rare Genetic Disorder of Heterotopic Ossification (2017) (0)
- Measuring outcomes in ultra-rare bone diseases: Methodology of the palovarotene fibrodysplasia ossificans progressiva clinical development programme (2020) (0)
- Molecular Genetics of Fibrodysplasia Ossificans Progressiva (2021) (0)
- Embryonic overexpression of the c-Fos protooncogene: A murine stem cell chimera applicable to the study of ibrodysplasia ossificans progressiva in humans : Fibrodysplasia Ossificans Progressiva (1998) (0)
- Early fibrodysplasia ossificans progressiva-like lesion formation in nude mice following implantation of lymphoblastoid cells from FOP patients (2005) (0)
- A prospective study of bone morphometry in anorexia nervosa (1990) (0)
- Skeletal metamorphosis in fiossifi cans progressiva (FOP) (2008) (0)
- RF18 | PSAT149 Joint Function and Quality of Life in Fibrodysplasia Ossificans Progressiva: Results from an International Burden of Illness Survey of Patients and Family Members (2022) (0)
- Book ReviewPractical Orthopaedic Medicine (1983) (0)
- 12 – Fibrous Dysplasia (2005) (0)
- Bone marrow transplant for fibrodysplasia ossificans progressiva: Has the hour arrived? Authors' reply (2001) (0)
- Fibrodysplasia Ossificans Progressiva (FOP): The Value of Studying a Rare Disorder (1997) (0)
- Exoneration of NF-&kgr;B Dysregulation in Fibrodysplasia Ossificans Progressiva (2003) (0)
- Heterotopic Ossification: The Keys to the Kingdom. (2018) (0)
- Case Report Fibrodysplasia Ossificans Progressiva and Pregnancy: A Case Series and Review of the Literature (2022) (0)
- COMPARISON OF BONE MINERAL DENSITY OF THE SPINE WITH DPA AND QUANTITATIVE CT IN PATIENTS WITH OSTEOPOROSIS (1987) (0)
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What Schools Are Affiliated With Frederick Samuel Kaplan?
Frederick Samuel Kaplan is affiliated with the following schools:
