Frits Koning
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Frits Koning's Degrees
- PhD Immunology Leiden University
- Masters Biology Leiden University
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(Suggest an Edit or Addition)Frits Koning's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase (2000) (682)
- Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study (2010) (597)
- Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid (1989) (545)
- Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. (1998) (518)
- Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes (2006) (494)
- Identification of a graft versus host disease-associated human minor histocompatibility antigen. (1995) (439)
- The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. (2002) (432)
- Randomized feeding intervention in infants at high risk for celiac disease. (2014) (401)
- Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules (2012) (392)
- Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease (2002) (380)
- The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses (2003) (361)
- Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease. (2006) (285)
- The Molecular Basis for Oat Intolerance in Patients with Celiac Disease (2004) (283)
- Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells (1997) (278)
- Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin. (1998) (270)
- Natural variation in toxicity of wheat: potential for selection of nontoxic varieties for celiac disease patients. (2005) (250)
- T Cell Responses Modulated Through Interaction Between CD8αα and the Nonclassical MHC Class I Molecule, TL (2001) (250)
- Characterization of cereal toxicity for celiac disease patients based on protein homology in grains. (2003) (250)
- Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease (2007) (248)
- Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94. (1996) (243)
- Narcolepsy — clinical spectrum, aetiopathophysiology, diagnosis and treatment (2019) (239)
- Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer. (2002) (215)
- The Ethiopian cereal tef in celiac disease. (2005) (214)
- Glutenin is involved in the gluten‐driven mucosal T cell response (1999) (214)
- The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway. (2005) (210)
- Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. (1988) (186)
- Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines. (1987) (178)
- Specific recognition of staphylococcal enterotoxin A by human T cells bearing receptors with the Vγ9 region (1990) (175)
- Celiac disease: how complicated can it get? (2010) (174)
- Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types (2017) (173)
- Human epidermal T cells predominantly belong to the lineage expressing alpha/beta T cell receptor (1990) (165)
- T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease (2014) (160)
- Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants (2006) (158)
- Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain. (1987) (158)
- Celiac disease--sandwiched between innate and adaptive immunity. (2006) (150)
- Guidance on allergenicity assessment of genetically modified plants (2017) (141)
- A New Type of Metal Recognition by Human T Cells (2003) (140)
- The implications of subunit interactions for the structure of the T cell receptor‐CD3 complex (1990) (132)
- Celiac disease: caught between a rock and a hard place. (2005) (130)
- Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease. (2012) (125)
- Mannose receptor mediated uptake of antigens strongly enhances HLA-class II restricted antigen presentation by cultured dendritic cells. (1997) (118)
- CD14 contributes to the adherence of human monocytes to cytokine-stimulated endothelial cells. (1991) (111)
- Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets. (2016) (110)
- Consumption of gluten with gluten-degrading enzyme by celiac patients: a pilot-study. (2013) (108)
- Intratumoral HPV16-Specific T Cells Constitute a Type I–Oriented Tumor Microenvironment to Improve Survival in HPV16-Driven Oropharyngeal Cancer (2017) (108)
- Cytosplore: Interactive Immune Cell Phenotyping for Large Single‐Cell Datasets (2016) (105)
- Memory CD4+ T cells are generated in the human fetal intestine (2018) (100)
- Update 2020: nomenclature and listing of celiac disease–relevant gluten epitopes recognized by CD4+ T cells (2019) (98)
- An immunodominant DQ8 restricted gliadin peptide activates small intestinal immune response in in vitro cultured mucosa from HLA-DQ8 positive but not HLA-DQ8 negative coeliac patients (2003) (98)
- Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex (2001) (97)
- Peptide binding characteristics of the coeliac disease-associated DQ(α1*0501, β1*0201) molecule (2007) (96)
- A mouse monoclonal antibody detecting a DR-related MT2-like specificity: serology and biochemistry. (1984) (94)
- Unique peptide binding characteristics of the disease-associated DQ(α1*0501, β1*0201) vs the non-disease-associated DQ(α1*0201, β1*0202) molecule (1997) (92)
- The role of HLA-DQ8 β57 polymorphism in the anti-gluten T-cell response in coeliac disease (2008) (88)
- T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL. (2001) (88)
- The PreventCD Study design: towards new strategies for the prevention of coeliac disease (2010) (83)
- Large-Scale Characterization of Natural Ligands Explains the Unique Gluten-Binding Properties of HLA-DQ21 (2008) (82)
- Phenotypic and Functional Characterization of CD4 T Cells Expressing Killer Ig-Like Receptors1 (2004) (80)
- A 40-Marker Panel for High Dimensional Characterization of Cancer Immune Microenvironments by Imaging Mass Cytometry (2019) (77)
- Efficient loading of HLA-DR with a T helper epitope by genetic exchange of CLIP. (1997) (77)
- Interplay between genetics and the environment in the development of celiac disease: perspectives for a healthy life. (2001) (76)
- Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance. (2014) (74)
- Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane (2004) (74)
- A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease (2010) (74)
- Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis (2015) (73)
- High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity (2019) (72)
- DRB1*0301 molecules recognize a structural motif distinct from the one recognized by most DR beta 1 alleles. (1992) (72)
- Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab° Dq8 Transgenic Mice1 (2009) (72)
- T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease (2019) (71)
- Tef in the diet of celiac patients in The Netherlands (2008) (70)
- Type 1 Diabetes-associated HLA-DQ8 Transdimer Accommodates a Unique Peptide Repertoire* (2011) (68)
- Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II molecules (1999) (67)
- KIR‐Ligand Mismatches Are Associated With Reduced Long‐Term Graft Survival in HLA‐Compatible Kidney Transplantation (2011) (65)
- The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice (2015) (63)
- Phenotypical and Functional Characterization of Small Intestinal TcRγδ+ T Cells in Coeliac Disease (1992) (61)
- Characterization of T cell receptors on resident murine dendritic epidermal T cells (1988) (61)
- Human dendritic cells shed a functional, soluble form of the mannose receptor. (1999) (60)
- A novel and sensitive method for the detection of T cell stimulatory epitopes of α/β- and γ-gliadin (2004) (60)
- AIDS-protective HLA-B*27/B*57 and chimpanzee MHC class I molecules target analogous conserved areas of HIV-1/SIVcpz (2010) (59)
- Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes. (2000) (59)
- Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with celiac disease. (2008) (58)
- Celiac disease: quantity matters (2012) (58)
- Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine (2018) (58)
- Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II (2012) (57)
- High expression of V gamma 8 is a shared feature of human gamma delta T cells in the epithelium of the gut and in the inflamed synovial tissue. (1994) (57)
- T-cell recognition of HLA-DQ2-bound gluten peptides can be influenced by an N-terminal proline at p-1 (2005) (57)
- Murine T cells express a cell surface receptor for multiple extracellular matrix proteins. Identification and characterization with monoclonal antibodies (1989) (57)
- Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells. (2011) (56)
- Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens (2015) (55)
- Randomised clinical study: Aspergillus niger‐derived enzyme digests gluten in the stomach of healthy volunteers (2015) (54)
- Gluten: a two-edged sword. Immunopathogenesis of celiac disease (2005) (54)
- T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation (1986) (53)
- Get into the groove! Targeting antigens to MHC class II (1999) (52)
- Determinants of Gliadin-Specific T Cell Selection in Celiac Disease (2015) (50)
- Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation (2012) (49)
- Gluten-Specific T Cells Cross-React between HLA-DQ8 and the HLA-DQ2α/DQ8β Transdimer (2011) (49)
- Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule. (2010) (49)
- Identification of a Novel Tumor-Specific CTL Epitope Presented by RMA, EL-4, and MBL-2 Lymphomas Reveals Their Common Origin (2000) (49)
- Peripheral murine CD3+, CD4-, CD8- T lymphocytes express novel T cell receptor gamma delta structures. (1988) (49)
- Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome. (2008) (46)
- The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose (2018) (46)
- Dissection of the HLA-DR4 Peptide Repertoire in Endocrine Epithelial Cells: Strong Influence of Invariant Chain and HLA-DM Expression on the Nature of Ligands1 (2004) (46)
- ImaCytE: Visual Exploration of Cellular Micro-Environments for Imaging Mass Cytometry Data (2021) (46)
- Coeliac disease and gluten-related disorders in childhood (2015) (46)
- Origin and immunophenotype of aberrant IEL in RCDII patients. (2012) (45)
- Natural peptides isolated from Gly86/Val86-containing variants of HLA-DR1,-DR 11, -DR13, and -DR52 (2005) (45)
- Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution. (2016) (45)
- Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor-CD3 expression in enteropathy-associated T-cell lymphoma. (2008) (44)
- Microbial transglutaminases generate T cell stimulatory epitopes involved in celiac disease (2008) (44)
- Functional human epidermal Langerhans cells that lack Birbeck granules. (1994) (44)
- Analysis of the donor-specific cytotoxic T lymphocyte repertoire in a patient with a long term surviving allograft. Frequency, specificity, and phenotype of donor-reactive T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ clones. (1990) (43)
- Distribution of HLA class II molecules in epidermal Langerhans cells in situ (1995) (42)
- Functional Killer Ig-Like Receptors on Human Memory CD4+ T Cells Specific for Cytomegalovirus1 (2009) (41)
- Ineffective Degradation of Immunogenic Gluten Epitopes by Currently Available Digestive Enzyme Supplements (2015) (41)
- A Leishmania homologue of receptors for activated C-kinase (LACK) induces both interferon-gamma and interleukin-10 in natural killer cells of healthy blood donors. (2000) (41)
- Peptide binding characteristics of the coeliac disease-associated DQ(alpha1*0501, beta1*0201) molecule. (1996) (41)
- CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes (2017) (40)
- PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors (2019) (40)
- HLA-DR4 Molecules in Neuroendocrine Epithelial Cells Associate to a Heterogeneous Repertoire of Cytoplasmic and Surface Self Peptides1 (2002) (38)
- A monoclonal antibody detecting an HLA-DQwl-related determinant. (2008) (38)
- TA10 and 2B3, two new alleles in the HLA-DQ region recognized by monoclonal antibodies. (1986) (38)
- Strongly increased efficiency of altered peptide ligands by mannosylation. (1998) (37)
- HLA class II expression on human epidermal Langerhans cells in situ: upregulation during the elicitation of allergic contact dermatitis. (1992) (36)
- Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity (2020) (36)
- Phenotypical heterogeneity among human t cell receptor γ/δ‐expressing clones derived from peripheral blood (1989) (36)
- DR4Dw4/DR53 molecules contain a peptide from the autoantigen calreticulin. (1995) (36)
- A Subset of Vδ1+ T Cells Proliferates in Response to Epstein‐Barr Virus‐Transformed B Cell Lines In Vitro (1993) (35)
- Functional and molecular characterization of B cell‐responsive Vδ1+ γδ T cells (1994) (35)
- Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library. (2010) (35)
- Predicting Cell Populations in Single Cell Mass Cytometry Data (2019) (34)
- Gluten tolerance in adult patients with celiac disease 20 years after diagnosis? (2008) (34)
- HLA‐DRβ chain residue 86 controls DRαβ dimer stability (1993) (34)
- Influence of dietary components on Aspergillus niger prolyl endoprotease mediated gluten degradation. (2015) (34)
- Impact of Peptides on the Recognition of HLA Class I Molecules by Human HLA Antibodies (2003) (34)
- The biosynthesis and assembly of T cell receptor alpha- and beta-chains with the CD3 complex. (1988) (34)
- Identification of an HLA‐DQ2 peptide binding motif and HLA‐DPw3‐bound self‐peptide by pool sequencing (1994) (33)
- Structural comparison of α/β and γ/δ T cell receptor‐CD3 complexes reveals identical subunit interactions but distinct cross‐linking patterns of T cell receptor chains (1990) (32)
- Independent association of T cell receptor beta and gamma chains with CD3 in the same cell (1987) (32)
- Coeliac disease: it takes three to tango! (2000) (32)
- A novel and sensitive method for the detection of T cell stimulatory epitopes of alpha/beta- and gamma-gliadin. (2004) (32)
- Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass. (2016) (32)
- The molecular basis of celiac disease (2003) (31)
- Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens (2019) (31)
- The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease (2015) (30)
- Coordinated Vγ and Vδ gene segment rearrangements in human T cell receptor γ/δ+ lymphocytes (1989) (30)
- Evidence for natural killer cell-mediated protection from metastasis formation in uveal melanoma patients. (2009) (29)
- Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies (2020) (29)
- Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule. (1997) (28)
- The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding. (1996) (28)
- The Probiotic Mixture VSL#3 Has Differential Effects on Intestinal Immune Parameters in Healthy Female BALB/c and C57BL/6 Mice. (2015) (28)
- Gene Expression Profiling Identifies Mechanisms of Protection to Recurrent Trinitrobenzene Sulfonic Acid Colitis Mediated by Probiotics (2012) (28)
- Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis. (2007) (27)
- Local communication among mucosal immune cells in patients with celiac disease. (2015) (27)
- Molecular localization of LB-Q1, a DRw52-like T-cell recognition epitope and identification at the genomic level of associated shared hybridizing fragments. (1987) (27)
- Validation of a new enzyme-linked immunosorbent assay to detect the triggering proteins and peptides for celiac disease: interlaboratory study. (2012) (26)
- The tortoise and the hare: slowly evolving T‐cell responses take hastily evolving KIR (2010) (26)
- Human suppressor T cell clones lack CD28 (1990) (26)
- Chronic schistosomiasis: dendritic cells generated from patients can overcome antigen-specific T cell hyporesponsiveness. (2000) (25)
- Advancing human health risk assessment (2019) (25)
- γδ T cell reactivity towards bacterial superantigens (1993) (25)
- Phenotypic variance in childhood coeliac disease and the HLA-DQ/DR dose effect (2009) (24)
- Natural variation in avenin epitopes among oat varieties: Implications for celiac disease (2011) (24)
- Phenotypical and functional characterization of small intestinal TcR gamma delta + T cells in coeliac disease. (1992) (24)
- Mannosylated PLP139–151 induces peptide-specific tolerance to experimental autoimmune encephalomyelitis (2005) (24)
- Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese women (2014) (23)
- Helminth infections drive heterogeneity in human type 2 and regulatory cells (2020) (22)
- CyteGuide: Visual Guidance for Hierarchical Single-Cell Analysis (2018) (22)
- Expression of C gamma 4 T cell receptors and lack of isotype exclusion by dendritic epidermal T cell lines. (1988) (22)
- Abrogation of Immunogenic Properties of Gliadin Peptides through Transamidation by Microbial Transglutaminase Is Acyl-Acceptor Dependent (2017) (21)
- An Arthritis‐Suppressive and Treg Cell–Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA‐Restricted T Cell Responses (2016) (20)
- DNAM-1 Mediates Epithelial Cell-Specific Cytotoxicity of Aberrant Intraepithelial Lymphocyte Lines from Refractory Celiac Disease Type II Patients (2011) (20)
- Screening for unrecognized coeliac disease in subfertile couples (2011) (20)
- Isolation of an HLA‐A2.1 extracted human minor histocompatibility peptide (1993) (20)
- Superior tumor protection induced by a cellular vaccine carrying a tumor-specific T helper epitope by genetic exchange of the class II-associated invariant chain peptide. (2000) (19)
- A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue (2020) (19)
- Adverse Effects of Wheat Gluten (2015) (19)
- Ia molecular localization of the DRw52 allodeterminant and the DRw52-like determinants defined by monoclonal antibodies. (1985) (19)
- Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule (2008) (19)
- Expression of the human T cell receptor as defined by anti-isotypic antibodies. (1987) (18)
- Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab Dq8 Transgenic Mice (2009) (18)
- Expansion of large granular lymphocytes in IL-2-driven 14-day-old fetal thymocytes in organ culture. (1990) (18)
- Pathophysiology of Celiac Disease (2014) (18)
- The Probiotic Mixture VSL#3 Dampens LPS-Induced Chemokine Expression in Human Dendritic Cells by Inhibition of STAT-1 Phosphorylation (2014) (18)
- Selective outgrowth of CD45RO+ V gamma 9+/V delta 2+ T-cell receptor gamma/delta T cells early after bone marrow transplantation. (1991) (17)
- CyTOFmerge: integrating mass cytometry data across multiple panels (2019) (17)
- HLA Reduces Killer Cell Ig-like Receptor Expression Level and Frequency in a Humanized Mouse Model (2013) (17)
- No genetic association of the human prolyl endopeptidase gene in the Dutch celiac disease population. (2005) (17)
- HLA class II restriction repertoire of antigen-specific T cells. II. Evidence for a new restriction determinant associated with DRw52 and LB-Q1. (1985) (16)
- Gluten Peptides and Celiac Disease (2003) (15)
- Enzymatic gluten detoxification: the proof of the pudding is in the eating! (2006) (15)
- Early-Life Compartmentalization of Immune Cells in Human Fetal Tissues Revealed by High-Dimensional Mass Cytometry (2019) (15)
- H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls (2019) (15)
- Reactivity of Human γδ T Cells to Staphylococcal Enterotoxins: a Restricted Reaction Pattern mediated by Two Distinct Recognition Pathways (1993) (15)
- Mannosylated PLP(139-151) induces peptide-specific tolerance to experimental autoimmune encephalomyelitis. (2005) (15)
- Production of a T cell hybridoma that expresses the T cell receptor gamma/delta heterodimer (1987) (15)
- 379 Can Prolyl Endoprotease Enzyme Treatment Mitigate the Toxic Effect of Gluten in Coeliac Patients (2010) (15)
- Multiple epitopes on a single DQ molecule from the DQw3-carrying haplotypes. (2008) (15)
- Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity (2021) (15)
- Induction of antigen specific CD4+ T cell responses by invariant chain based DNA vaccines. (2001) (15)
- CD4‐independent T cells impair TCR triggering of CD4‐dependent T cells: a putative mechanism for T cell affinity maturation (2001) (14)
- The probiotic mixture VSL#3 mediates both pro- and anti-inflammatory responses in bone marrow-derived dendritic cells from C57BL/6 and BALB/c mice (2014) (14)
- Immunization with mannosylated peptide induces poor T cell effector functions despite enhanced antigen presentation. (2008) (14)
- Best Abstracts (2004) (14)
- HLA-DR beta chain residue 86 controls DR alpha beta dimer stability. (1993) (14)
- Safety Assessment of Immune-Mediated Adverse Reactions to Novel Food Proteins. (2019) (14)
- Altered peptide ligands and wild‐type peptide induce indistinguishable responses of a human Th0 clone (1998) (14)
- Development and in-house validation of a competitive ELISA for the quantitative detection of gluten in food (2017) (14)
- Allergenicity Assessment of Novel Food Proteins: What Should Be Improved? (2020) (13)
- Severe combined immunodeficiency in man with an absence of immunoglobulin gene rearrangements but normal T cell receptor assembly (1990) (13)
- Visualizing Dynamic Changes at the Maternal-Fetal Interface Throughout Human Pregnancy by Mass Cytometry (2020) (13)
- Staphylococcal enterotoxin-mediated human T-T cell interactions. (1992) (13)
- An improved RT-PCR method for the detection of killer-cell immunoglobulin-like receptor (KIR) transcripts (2006) (13)
- A subset of V delta 1+ T cells proliferates in response to Epstein-Barr virus-transformed B cell lines in vitro. (1993) (12)
- Lactobacillus plantarum NCIMB8826 ameliorates inflammation of colon and skin in human APOC1 transgenic mice. (2016) (12)
- Lymphocyte antigen receptors: a common design? (1991) (12)
- The gamma delta T cell receptor. (1989) (12)
- Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease (2021) (12)
- Cutting Edge: Killer Ig-Like Receptors Mediate “Missing Self” Recognition In Vivo1 (2009) (11)
- Successful treatment of coeliac disease by allogeneic haematopoietic stem cell transplantation. (2010) (11)
- Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics (2017) (11)
- Phenotypical and functional analysis of B lymphocytes of two siblings with combined immunodeficiency and defective expression of major histocompatibility complex (MHC) class II antigens on mononuclear cells (1987) (11)
- Tissue transglutaminase: master regulator of celiac disease? (2003) (11)
- Definition of agonists and design of antagonists for alloreactive T cell clones using synthetic peptide libraries. (1999) (11)
- Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer (2020) (10)
- Synaptojanin 2 is recognized by HLA class II-restricted hairy cell leukemia-specific T cells (2003) (10)
- Increased HLA-DQ2-affinity of a synthetic gliadin peptide by acid-induced deamidation of glutamine residues. (1998) (9)
- Anti-alpha-gliadin antibodies (AGA) in the serum of coeliac children and controls recognize an identical collection of linear epitopes of alpha-gliadin. (1998) (9)
- γδ T cells are effectors of immunotherapy in cancers with HLA class I defects (2023) (9)
- Celiac Disease: Past, Present, and Future Challenges Dedicated to the Memory of Our Friend and Colleague, Prof David Branski (1944–2013) (2014) (9)
- The Impact of Single Amino Acid Substitutions in CD3γ on the CD3ϵγ Interaction and T-Cell Receptor–CD3 Complex Formation (2006) (9)
- A Specialist Macaque MHC Class I Molecule with HLA-B*27–like Peptide-Binding Characteristics (2017) (9)
- Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance (2016) (9)
- Functional and molecular characterization of B cell-responsive V delta 1+ gamma delta T cells. (1994) (9)
- Therapy in RCDII: Rationale for Combination Strategies? (2015) (8)
- Genetic and functional analysis of pyroglutamyl-peptidase I in coeliac disease (2006) (8)
- FcRγ‐chain deficiency reduces the development of diet‐induced obesity (2015) (8)
- Expression of CD11, CDw15, and transferrin receptor antigens on human hematopoietic progenitor cells. (1986) (8)
- Right on target: Novel approaches for the direct visualization of CD1-specific T cell responses (2001) (8)
- Intolerance of celiac disease patients to bovine milk is not due to the presence of T-cell stimulatory epitopes of gluten. (2009) (8)
- Recent insight in the pathophysiology of coeliac disease: relevance to rheumatoid arthritis. (2015) (8)
- Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface (2022) (8)
- Enhancement of HLA class II restricted antigen presentation by mannose-receptor-mediated uptake. (1997) (7)
- Antibody dependent cellular cytotoxicity mediated by HLA-class II specific monoclonal antibodies. (2008) (7)
- Dendritic cells promote expansion and survival of aberrant TCR-negative intraepithelial lymphocyte lines from refractory celiac disease type II patients. (2014) (7)
- TCR γδ cells: Antigen-driven expansion of distinct subsets based on localization and antigen specificity (1991) (7)
- Celiac Disease: Across the Threshold of Tolerance (2008) (7)
- γδ T-cell receptor repertoire in human peripheral blood and thymus (2005) (7)
- Differential Expression of DRw52‐Like Determinants Detected by Monoclonal Antibodies (1987) (7)
- Food -related strategies towards reduction of gluten intolerance and gluten sensitivity (2011) (7)
- T cells from the small intestinal mucosa of coeliac disease patients recognise a unique peptide sequence of gliadin (1998) (7)
- Immobilized staphylococcal enterotoxin A is sufficient to induce T cell proliferation. (1993) (7)
- Lack of relationship of AT1001 to zonulin and prehaptoglobin-2: clinical implications (2020) (7)
- Functional polymorphism of the HLA-DR beta III chain. (1988) (7)
- The Influence of the Workshop Monoclonal Antibodies on CML, AgTR, PLT, ADCC, and NK Cell Activity. Functional Studies with Workshop Antibodies (1986) (7)
- Gamma delta T cell reactivity towards bacterial superantigens. (1993) (7)
- Celiac disease: sandwiched between innate and adaptive immune responses induced by gluten. (2008) (7)
- Divergent and invariant HLA class II beta chain isoelectric points. (1986) (6)
- IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement (2018) (6)
- A novel T-cell-defined HLA-DR polymorphism not predicted from the linear amino acid sequence. (1989) (6)
- Mannosylated self‐peptide inhibits the development of experimental autoimmune encephalomyelitis via expansion of nonencephalitogenic T cells (2008) (6)
- γδ T cells in coeliac disease (1990) (6)
- Reactivity of human gamma delta T cells to staphylococcal enterotoxins: a restricted reaction pattern mediated by two distinct recognition pathways. (1993) (6)
- Ultrastructural localization of HLA-DR and HLA-DQ molecules in Langerhans cells and B cells: an immunoelectronmicroscopic study. (1988) (6)
- Strategies for Prevention of Celiac Disease (2008) (6)
- Typing for HLA class II at the product level. (1985) (6)
- T-cell receptor usage of interleukin-2-responsive peripheral gamma delta T cells. (1995) (6)
- Selective removal of clonogenic neoplastic B cells from human bone marrow using anti-HLA-DQ antibodies and complement. (1986) (6)
- The million-dollar question: is "gluten-free" food safe for patients with celiac disease? (2013) (5)
- Gamma delta T cells in coeliac disease. (1990) (5)
- Ranking of immunodominant epitopes in celiac disease: Identification of reliable parameters for the safety assessment of innovative food proteins. (2021) (5)
- Memory CD8+ T cell heterogeneity is primarily driven by pathogen-specific cues and additionally shaped by the tissue environment (2020) (5)
- Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques (2013) (5)
- A biased view toward celiac disease (2016) (5)
- Analysis of early fetal T-cell receptor δ chain in humans (2004) (5)
- The impact of single amino acid substitutions in CD3gamma on the CD3epsilongamma interaction and T-cell receptor-CD3 complex formation. (2006) (5)
- Identification of Two Distinct Function γδ TCR Complexes on the Surface of a Human T Cell Clone (1995) (4)
- Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells (2021) (4)
- The majority of HLA-DR3 alloreactive T cells is peptide specific, but does not recognize known DR3-bound sequences. (1998) (4)
- Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease (2020) (4)
- Natural peptides isolated from Gly 86 /Val 86 -containing variants of HLA-DR1,-DR (1996) (4)
- Heterogeneity of HLA Class II Gene Products as Studied in a Family by Sequential Immunoprecipitation (1984) (4)
- Predicting cell types in single cell mass cytometry data (2018) (4)
- Interactive Visual Analysis of Mass Cytometry Data by Hierarchical Stochastic Neighbor Embedding Reveals Rare Cell Types (2017) (4)
- γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects (2021) (4)
- Identification of a new lymphocyte subset surface antigen, the expression of which disappears after in vitro and in vivo stimulation. Distribution, biochemistry, and functional studies. (1986) (4)
- Coordinated V gamma and V delta gene segment rearrangements in human T cell receptor gamma/delta+ lymphocytes. (1989) (4)
- prolyl endoprotease: implications for celiac disease (2006) (3)
- Isolation and Cloning of Gluten-Specific T Cells in Celiac Disease. (2015) (3)
- Ligands HLA-DM Expression on the Nature of Strong Influence of Invariant Chain and Repertoire in Endocrine Epithelial Cells : Dissection of the HLA-DR 4 Peptide (2004) (3)
- Statement of the Prolamin Working Group on the Determination of Gluten in Fermented Foods Containing Partially Hydrolyzed Gluten (2021) (3)
- Synthetic Peptide libraries for T-cell epitope identification. (2000) (3)
- Abstracts from the Food Allergy and Anaphylaxis Meeting 2016 (2017) (3)
- Celiac disease: New therapies on the horizon. (2022) (3)
- Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: comment on the article by Pierer et al. (2012) (3)
- implications for coeliac disease endoprotease in a gastrointestinal model: Efficient degradation of gluten by a prolyl (2008) (3)
- γδ T cells in coeliac disease. Discussion (1990) (3)
- Phenotypical heterogeneity among human T cell receptor gamma/delta-expressing clones derived from peripheral blood. (1989) (3)
- Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease (2022) (3)
- P363 Locally injected allogeneic bone marrow-derived mesenchymal stromal cells for the treatment of refractory proctitis: clinical results of a phase IIa trial (2021) (2)
- Single-Cell Analysis of Refractory Celiac Disease Demonstrates Inter- and Intra-Patient Aberrant Cell Heterogeneity (2022) (2)
- Celiac disease and malignancy: an immunological basis? (1997) (2)
- Human γδ T‐Cells in the Epithelium of the Gut and in the Inflamed Synovial Tissue Preferentially Express the Vγ8 T‐Cell Receptor Chain (1995) (2)
- Structural comparison of alpha/beta and gamma/delta T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains. (1990) (2)
- Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types (2017) (2)
- Memory CD4+ T cells are generated in the human fetal intestine (2019) (2)
- The power and potential of BIOMAP to elucidate host‐microbiome interplay in skin inflammatory diseases (2021) (2)
- T cell receptor gamma/delta chain diversity (1988) (2)
- Presence of gluten proteins in breast milk: implications for the development of celiac disease (2008) (1)
- Interleukin-2 immunotherapy reveals human regulatory T cell subsets with distinct functional and gatekeeper features (2022) (1)
- Mass Cytometric Analysis of Early-Stage Mycosis Fungoides (2022) (1)
- Function of DRw52 and LB-Q1 in Antigen Presentation (1984) (1)
- DOP64 Endoscopically injected allogeneic mesenchymal stromal cells alter the mucosal immune cell compartment in patients with ulcerative proctitis (2021) (1)
- Local and systemic immune profiles of human pancreatic ductal adenocarcinoma revealed by single-cell mass cytometry (2022) (1)
- Gluten toxicity, how to get rid of it? (2011) (1)
- Properties of HLA-DQ2 Ligands Explains the Unique Gluten-Binding Large-Scale Characterization of Natural (2013) (1)
- Sa1772 Ilc-Like Lymphomas in Refractory Celiac Disease Type II Respond to Multiple Common γ-Chain Cytokines and Are Sensitive to JAK-Inhibitors (2015) (1)
- Transdimer β / DQ 8 α HLA-DQ 8 and the HLA-DQ 2 Gluten-Specific T Cells Cross-React between Papadopoulos (2011) (1)
- Coeliac Disease and Gluten-Related Disorders (2015) (1)
- B-cell epitopes of α-gliadin in celiac children and in controls (1997) (1)
- Selection in Celiac Disease Determinants of Gliadin-Specific T Cell (2015) (1)
- PS13 - 66. The type 1 diabetes associated HLA-DQ8-transdimer accommodates a unique islet peptide repertoire (2011) (1)
- Analysis of early fetal T-cell receptor delta chain in humans. (1990) (1)
- Immunoelectron Microscopic Analysis of Major Histocompatibility Class II Expression on Human Epidermal Langerhans Cells (1995) (1)
- Analysis of the donor-specific cytotoxic T-cell repertoire in a patient with a long-term surviving kidney allograft. (1990) (1)
- Performance characteristics of a new competitive DQ2.5-glia-α3 gliadin ELISA (2020) (1)
- Cytosplore: Interactive Visual Single-Cell Profiling of the Immune System (2019) (1)
- LB-Q1 and LB-Q2: Population Genetics in Dutch Caucasoids and Inhibition Studies with Monoclonal Antibodies (1984) (0)
- Celiac disease and malignancy : An immunological basis? Discussion (1997) (0)
- NK cells in stem cell transplantation as tumour therapy: dissecting the role of KIR in an in vivo mouse model (2005) (0)
- 28-OR Control of HIV-1 replication: Human long-term non-progressors and chimpanzees share MHC class I molecules with similar functional properties (2011) (0)
- SP0209 Lessons from Coeliac Disease (2015) (0)
- Nature of Ligands Invariant Chain and HLA-DM Expression on the Endocrine Epithelial Cells: Strong Influence of Dissection of the HLA-DR4 Peptide Repertoire in (2011) (0)
- Coeliac disease: on the way to immunotherapy! (2001) (0)
- 114 A Th-1 LIKE CYTOKINE PRODUCTION PATTERN OF CD8− TcRa T-CELLS FROM THE SMALL INTESTINE OF COELIAC PATIENTS (1995) (0)
- New developments for the allergenicity assessment of GM plants (2017) (0)
- Receptors of CD4 T Cells Expressing Killer Ig-Like Phenotypic and Functional Characterization (2004) (0)
- Visualizing the players of the maternal immune response at the maternal-fetal interface by high-dimensional mass cytometry (2017) (0)
- PS19 - 88. Mast cell deficient mice on a high fat diet have altered immune cell infiltration in their adipose tissue (2012) (0)
- Langerhans cells and EBV-transformed B cells differ with respect to the distribution of endosomal/lysosomal markers in the MHC class II compartment. (1996) (0)
- TCR gamma delta cells: antigen-driven expansion of distinct subsets based on localization and antigen specificity. (1991) (0)
- Brief Derinitive Report PRODUCTION OF A T CELL HYBRIDOMA THAT EXPRESSES THE T CELL RECEPTOR 7/b HETERODIMER BY (2003) (0)
- Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis. (2023) (0)
- Synaptojanin 2B is recognized by an HLA class II restricted Hairy Cell Leukemia specific T cell clone. (2001) (0)
- Letter: gluten digestion in the stomach and duodenum by Aspergillus niger‐derived enzyme – things to ponder. Authors’ reply (2015) (0)
- ====CHAPTERS==== IMMUNOELECTRON MICROSCOPIC ANALYSIS OF MAJOR HISTOCOMPATIBILITY Cuss II ExPREsSION ON HUMAN EPIDERMAL (1995) (0)
- The HLA A03 Supertype and Several Pan Species Major Histocompatibility Complex Class I A Allotypes Share a Preference for Binding Positively Charged Residues in the F Pocket: Implications for Controlling Retroviral Infections (2020) (0)
- High-Dimensional Mass Cytometric Analysis of the Bone Marrow Compartment Identifies a Disease-Specific Immune Cell Network in Aplastic Anemia (2022) (0)
- 4 B CELL EPITOPES IN COELIAC DISEASE (1995) (0)
- Prevention against illness by means of a mouse model for MS (2002) (0)
- Epithelial cells expressing class II molecules: can they present naturally processed peptides? (1997) (0)
- Chapter Fine specificity of monoclonal antibodies against celiac disease-inducing peptides present in the gluteome (2011) (0)
- Best Abstracts (2004) (0)
- Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation (2023) (0)
- 54-OR: KIR-ligand mismatches are associated with reduced long-term graft survival in HLA fully compatible kidney transplantation (2011) (0)
- OP27 High-dimensional mass cytometry reveals the immune cell landscape in inflammatory bowel disease (2019) (0)
- Abstract A063: Multidimensional cytometric analysis of colorectal cancer reveals novel and diverse mediators of antitumor immunity (2019) (0)
- High-dimensional mass cytometry analysis of immune cells in emphysematous lung tissue (2020) (0)
- Celiac Disease: Can a Th1-Mediated Disease Teach Us How to Study the Non-Ige-Mediated Food Allergies? (2018) (0)
- Bacterial immune modulation of the cytokine response elicited by gliadin in an in vitro model ofceliac disease (2013) (0)
- Characterization of Intestinal τδ and αβ T-cell Receptor Positive Cells in Coeliac Disease (1991) (0)
- Cytomegalovirus T Cells Specific for + Human Memory CD4 Functional Killer Ig-Like Receptors on (2009) (0)
- Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules (2012) (0)
- Immunotherapy of celiac disease: fact or fallacy? (2002) (0)
- Receptors of CD 4 T Cells Expressing Killer Ig-Like Phenotypic and Functional Characterization (2004) (0)
- Characterization of HLA-DQ-Specific Peptide-Binding Motifs. (2000) (0)
- Immune response to 100 mg gluten introduced at 4 months of age: results from the PreventCD cohort. (2011) (0)
- A Tertiary Twist to the Transglutaminase Tale (2007) (0)
- Biomarker identification to assess effects of bone-marrow derived mesenchymal stromal cell-therapy in emphysema through immune profiling (2022) (0)
- PO-260 Deep phenotyping of colorectal cancers by high-dimensional mass cytometry reveals tumor-specific immune landscapes (2018) (0)
- CHARACTERIZATION OF INTESTINAL γδ T-CELLS IN COELIAC DISEASE (1991) (0)
- Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques (2013) (0)
- Diversity of γs̀ T‐cell Receptors Expressed by Dendritic Epidermal Cell Lines (1988) (0)
- Cell Surface Molecules, Immunoprecipitation of (1998) (0)
- Receptorsof CD4 T Cells Expressing Killer Ig-Like Phenotypic and Functional Characterization (2004) (0)
- Three Functionally Distinct DRw52 Subtypes Are Alleles of the DRβIII Locus (1989) (0)
- GAMMA DELTA T CELLS IN COELIAC DISEASE. DISCUSSION (1990) (0)
- Editorial: enhancing gluten digestion in the stomach – a further help to minimise unintentional ingestion? Authors’ reply (2015) (0)
- Properties of HLA-DQ 2 Ligands Explains the Unique Gluten-Binding Large-Scale Characterization of Natural Papadopoulos (2008) (0)
- TCR γ Chain Expression on Human Peripheral Blood T Lymphocytes (1989) (0)
- Mass Cytometry Marker Panel Extension (2017) (0)
- P079 High-dimensional mass cytometry after local MSC treatment in patients with refractory proctitis shows an effect on the myeloid compartment: preliminary data (2020) (0)
- Mediate ''Missing Self'' Recognition In Vivo Cutting Edge: Killer Ig-Like Receptors (2009) (0)
- Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation (2012) (0)
- Coeliac Disease in Subfertile Couples in the Netherlands (2011) (0)
- MHC CLASS I MOLECULE WITH NON-CLASSICAL FEATURES HAS HLA-B*27-LIKE PEPTIDE-BINDING CHARACTERISTICS (2015) (0)
- Persistent Increase of Intra-Epithelial T-Cell Receptor τ δ Cells in Coeliac Disease (1991) (0)
- PROBIOTICS INHIBIT THE DEVELOPMENT OF INFLAMMATORY PROCESSES IN RECURRENT TNBS-COLITIS : INSIGHTS FROM INTESTINAL TRANSCRIPTOME ANALYSIS (2011) (0)
- PS13 - 3. Fcγ- and ε-receptors do not play a role in the initial development of insulin resistance (2013) (0)
- Recognition of HLA-DQ gluten is mediated by a relatively conserved set of T-cell receptors that predominate in patients and appear absent in healthy individuals (2015) (0)
- Increased amount of regulatory T cells may be required in attaining an ongoing uncomplicated pregnancy after unexplained recurrent pregnancy loss. (2021) (0)
- Celiac disease: a functional genomics approach to define molecular pathways (2002) (0)
- Towards peptide based therapeutics-Applications in celiac disease and infectious diseases (2006) (0)
- Functional human epidermal Langerhans cells that lack birbeck granules (1993) (0)
- L3-12 complex (2015) (0)
- Strong Influence of Invariant Chain and Repertoire in Endocrine Epithelial Cells: Dissection of the HLA-DR4 Peptide (2013) (0)
- Visual Analysis of Tissue Images at Cellular Level (2021) (0)
- Chapter 5 Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for celiac disease (2011) (0)
- PS15 - 75. Differences in adipocyte morphology and immune cell population in adipose tissues from metabolically healthy and unhealthy severely obese women (2011) (0)
- Celiac disease: quantity matters (2012) (0)
- Correction: A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease (2012) (0)
- Y-Chain T Cell Receptors on Denoritic Epidermal Cells (1988) (0)
- 84 PEPTIDE-BINDING PROPERTIES OF THE COELIAC DISEASE-ASSOCIATED HLA-DQ(α1*0501, β1*0201) MOLECULE (1996) (0)
- Humanized Mouse Model Expression Level and Frequency in a HLA Reduces Killer Cell Ig-like Receptor (2013) (0)
- 353 Localization and Phenotype of the Gliadin-Specific T-Cell Response After Oral Gliadin Intake in Mice (2009) (0)
- Isolation of gluten-specific, HLA-DQ-restricted T cells from the small intestinal mucosa of a coeliac disease patient (1997) (0)
- 43-OR: Evidence for Natural Killer Cell Induced Graft Loss in HLA Full Compatible Kidney Transplantation (2010) (0)
- THE MACAQUE A2*05 GENE ENCODES FOR SPECIALIST MHC MOLECULES WITH HLA-B*27-LIKE PEPTIDE-BINDING CHARACTERISTICS (2017) (0)
- Su2096 Gluten Degrading Enzyme Effectively Digests Gluten in the Stomach and Small Intestine of Healthy Volunteers (2014) (0)
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