Fyodor Urnov
#95,092
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Russian-American biologist
Fyodor Urnov's AcademicInfluence.com Rankings
Fyodor Urnovbiology Degrees
Biology
#6888
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#9697
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Biotechnology
#275
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#277
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Genetics
#978
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#1074
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Molecular Biology
#2546
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#2587
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Biology
Fyodor Urnov's Degrees
- PhD Molecular and Cell Biology University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Fyodor Urnov Influential?
(Suggest an Edit or Addition)According to Wikipedia, Fyodor Dmitriyevich Urnov is Russian-born biomedical researcher and who has played a leading role in the field of genome editing. He is a Professor of Genetics, Genomics, and Development at the University of California, Berkeley and Director of the Center for Translational Genomics at the university's Innovative Genomics Institute. In 2005 Urnov and his colleagues coined the term "genome editing" and demonstrated the first use of ZFNs to edit DNA in human cells. Urnov is considered a pioneering figure in the field of genome editing and his work has been cited widely.
Fyodor Urnov's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A TALE nuclease architecture for efficient genome editing (2011) (1947)
- Genome editing with engineered zinc finger nucleases (2010) (1937)
- Highly efficient endogenous human gene correction using designed zinc-finger nucleases (2005) (1607)
- Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions (2010) (1116)
- Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases (2009) (1054)
- Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases (2008) (1010)
- Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases (2009) (926)
- Heritable Targeted Gene Disruption in Zebrafish Using Designed Zinc Finger Nucleases (2008) (922)
- Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery (2007) (888)
- Precise genome modification in the crop species Zea mays using zinc-finger nucleases (2009) (853)
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations (2011) (675)
- Targeted Genome Editing Across Species Using ZFNs and TALENs (2011) (633)
- K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates (2015) (533)
- Genetic engineering of human ES and iPS cells using TALE nucleases (2011) (489)
- Don’t edit the human germ line (2015) (435)
- Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures (2011) (404)
- Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases (2007) (391)
- Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases (2008) (377)
- Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription. (1999) (330)
- Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. (2010) (295)
- Translating Dosage Compensation to Trisomy 21 (2013) (280)
- Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells (2011) (241)
- LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction (2014) (240)
- Targeted transgene integration in plant cells using designed zinc finger nucleases (2009) (221)
- Trait stacking via targeted genome editing. (2013) (209)
- Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology (2010) (200)
- Chromosomal translocations induced at specified loci in human stem cells (2009) (200)
- Chromatin remodeling and transcriptional activation: the cast (in order of appearance) (2001) (197)
- Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases (2012) (162)
- In vivo cleavage of transgene donors promotes nuclease‐mediated targeted integration (2013) (160)
- Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing. (2014) (149)
- Targeted Gene Addition to a Safe Harbor locus in human CD34+ Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease (2016) (133)
- Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases (2011) (131)
- Functional footprinting of regulatory DNA (2015) (123)
- Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells (2017) (119)
- Identification of Chromosome Sequence Motifs That Mediate Meiotic Pairing and Synapsis in C. elegans (2009) (114)
- Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation (2014) (107)
- Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease (2019) (105)
- Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells With Zinc Finger Nucleases for Cellular Imaging (2012) (92)
- Improved specificity of TALE-based genome editing using an expanded RVD repertoire (2015) (90)
- Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells (2014) (84)
- Mammalian interspecies substitution of immune modulatory alleles by genome editing (2016) (81)
- Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing (2018) (80)
- Targeting of N‐CoR and histone deacetylase 3 by the oncoprotein v‐ErbA yields a chromatin infrastructure‐dependent transcriptional repression pathway (2000) (78)
- Co-repressor complexes and remodelling chromatin for repression. (2000) (77)
- Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. (2003) (76)
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations (2011) (70)
- Transcriptional activation of Brassica napus β-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor. (2012) (65)
- Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major (2018) (64)
- A necessary good: nuclear hormone receptors and their chromatin templates. (2001) (61)
- NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation. (2009) (59)
- Above and Within the Genome: Epigenetics Past and Present (2001) (57)
- A call for science-based review of the European court's decision on gene-edited crops (2018) (45)
- DNA amplification in DNA puff II/9A of Sciara coprophila. (1993) (39)
- Methylation and the genome: the power of a small amendment. (2002) (38)
- A feel for the template: zinc finger protein transcription factors and chromatin. (2002) (38)
- Chromatin Modification (37)
- Designed transcription factors as tools for therapeutics and functional genomics. (2002) (36)
- Chromatin remodeling as a guide to transcriptional regulatory networks in mammals (2003) (35)
- Blueprint for a pop-up SARS-CoV-2 testing lab (2020) (34)
- Genome Editing B.C. (Before CRISPR): Lasting Lessons from the "Old Testament". (2018) (33)
- Activation domains for controlling plant gene expression using designed transcription factors. (2013) (31)
- Molecular mechanisms of corepressor function. (2001) (27)
- Thyroid hormone receptor, v-ErbA, and chromatin. (2000) (24)
- Biotechnologies and therapeutics: chromatin as a target. (2002) (23)
- Chromatin organisation and human disease (2000) (23)
- Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo (2002) (21)
- An Array of Positioned Nucleosomes Potentiates Thyroid Hormone Receptor Action in Vivo * (2001) (21)
- Chromatin as a Tool for the Study of Genome Function in Cancer (2003) (20)
- Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus (2021) (19)
- Persistent repression of tau in the brain using engineered zinc finger protein transcription factors (2021) (18)
- A DNase I hypersensitive site flanks an origin of DNA replication and amplification in Sciara (2002) (15)
- Genome editing: The domestication of Cas9 (2016) (14)
- Methods to map origins of replication in eukaryotes (1999) (13)
- The Genetic Diversity and Structure of Linkage Disequilibrium of the MTHFR Gene in Populations of Northern Eurasia (2012) (12)
- Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila (2013) (12)
- A path to efficient gene editing (2018) (12)
- Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis (2012) (11)
- 35 Differential DNA Replication in Insects (1996) (11)
- Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies (2015) (10)
- Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples (2021) (9)
- Piloting an integrated SARS-CoV-2 testing and data system for outbreak containment among college students: A prospective cohort study (2021) (9)
- Prime Time for Genome Editing? (2020) (8)
- Chromatin Remodeling by the Thyroid Hormone Receptor in Regulation of the Thyroid-stimulating Hormone α-Subunit Promoter* (2001) (8)
- Ctrl-Alt-inDel: genome editing to reprogram a cell in the clinic. (2018) (8)
- The Cas9 Hammer-and Sickle: A Challenge for Genome Editors. (2021) (7)
- Differential DNA Replication in Insects (2005) (7)
- Chromatin Remodelling and Histone Modification in Transcription Regulation (2001) (6)
- Precise Genome Modification in Maize Using Zinc-Finger Nucleases (2009) (6)
- CRISPR–Cas9 can cause chromothripsis (2021) (6)
- Evidence generation and reproducibility in cell and gene therapy research: A call to action (2021) (6)
- Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells (2014) (6)
- Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples (2021) (5)
- 713. Gene Correction Therapy Using Designed Zinc Finger-Based Endonucleases (2004) (5)
- Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing (2011) (5)
- Faculty Opinions recommendation of The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling. (2005) (5)
- 974. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs) (2005) (5)
- Biological techniques: Edit the genome to understand it (2014) (5)
- 85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell Anemia (2005) (4)
- 53. From GWAS To the Clinic: Genome-Editing the Human BCL11A Erythroid Enhancer for Fetal Globin Elevation in the Hemoglobinopathies (2015) (4)
- Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans (2009) (4)
- Clonal Analysis of Human Bone Marrow CD34+ Cells Edited By BCL11A-Targeting Zinc Finger Nucleases Reveals Clinically Relevant Levels of Fetal Globin Expression in Edited Erythroid Progeny (2015) (4)
- Erratum: Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells (Stem Cell Reports (2014) 2 (838-852)) (2014) (3)
- Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling. (2020) (3)
- Human genome editing as a tool to establish causality (2014) (3)
- LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples (2021) (3)
- Genome Editing of the Bcl11A Erythroid Specific Enhancer in Bone Marrow Derived Hematopoietic Stem and Progenitor Cells for the Treatment of Sickle Cell Disease (2015) (3)
- IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2 (2020) (3)
- 239. Preclinical Studies for the First Hematopoietic Stem Cell (HSC) Gene Editing Trial: Phase 1 Study of Beta-Thalassemia With Autologous Transplantation of Zinc Finger Nuclease-Treated HSC To Upregulate Fetal Hemoglobin (2015) (2)
- Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling. (2020) (2)
- An ode to gene edits that prevent deafness. (2018) (2)
- Autologous Hematopoietic Stem/Progenitor Cell (HSPC) Therapy For Monogenic Blood Disorders: Scalable, cGMP-Compliant Process For Generating Highly Efficient Genome Edited HSPC (2013) (2)
- 54. Genome Editing of Primary Human CD34+ Hematopoietic Stem Cells Enables a Safe Harbor Targeted Gene Addition Therapeutic Strategy for Chronic Granulomatous Disease (2015) (2)
- Cas9 in action: no more known unknowns? (2017) (2)
- Regulatory DNA keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification (2020) (1)
- 337. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome with Engineered Zinc Finger Nucleases (2005) (1)
- Chromatin Structure and Modification (2003) (1)
- A7 Drug discovery approach for rare neurological diseases: using novel zinc finger protein technology to develop potential therapy for huntington’s disease (2016) (1)
- 346. Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integration Defective Lentiviral Delivery (2005) (1)
- 738. Towards Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integrase Defective Lentiviral Delivery (2006) (1)
- An ode to gene edits that prevent deafness (2017) (1)
- Hijack of CRISPR defences by selfish genes holds clinical promise (2019) (1)
- 714. Structure-Based Engineering of the FokI DNA Cleavage Domain in the Context of a Chimeric Endonuclease: Towards Maximally Efficient |[ldquo]|Gene Editing|[rdquo]| Therapy (2004) (1)
- Potent and Timed Epigenetic Repression of PD-1 in Human T Cells (2018) (1)
- Taking it to the Clinic: Genome Editing for Blood Disorders (2014) (1)
- Regulatory Reprogramming of Erythropoiesis By DNMT3A Mutation (2018) (0)
- Databases of regulatory sequences, methods for their manufacture and use (2001) (0)
- 1003. Targeted Site-Specific Integration in Human Cells Using Designed Zinc Finger Nucleases (2006) (0)
- Quantitative dialing of gene expression via precision targeting of KRAB repressor (2020) (0)
- Plant with targeted modification of the endogenous malate dehydrogenase gene (2013) (0)
- Faculty Opinions recommendation of Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo. (2009) (0)
- In memoriam – Alan P. Wolffe (21.6.1959–26.5.2001) (2002) (0)
- VPAAMAERPFQCRICMRNFS RSDSLSV HIRTHTGEKPFACDICGRKFA HNDSRKN HTKIHTGEKPFQCRICMRKFA DQSNLRA HTKIHTHPRAPIPKPFQCRICMRNFS RSANL AR HIRTHTGEKPFACDICGRKFA QSGNLAR HTKIHLRGS VPAAMAERPFQCRICMRNFS RSDHLSA HIRTHTGEKPFACDICGRKFA SYWSRTV HTKIHTHPRAPIPKPFQCRICMRNFS RSDALSV HIRTHTGEKPFACDICGRKFA DSSHRT R HTKIHTGSQK (2011) (0)
- Zinc finger protein design that target genes enolpyruvyl shikimate 5-phosphate synthase-3- (2008) (0)
- Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing. (2020) (0)
- 555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene (2006) (0)
- 35 DNA Replication in Insects (1996) (0)
- Faculty Opinions recommendation of Establishment of sister chromatid cohesion at the S. cerevisiae replication fork. (2006) (0)
- Targeted integration in the ppp1r12c-position (2008) (0)
- into a safe harbor locus in the human genome isogenic settings using zinc finger nuclease-driven transgenesis Functional genomics , proteomics , and regulatory DNA analysis in Material Supplemental (2010) (0)
- Faculty Opinions recommendation of Rapid diversification of cell signaling phenotypes by modular domain recombination. (2010) (0)
- P-3 Transgenic Approaches Towards Improved Drought Tolerance in Turf and Forage Grass ( Paspalum notatum Flugge ) (0)
- Thyroid Hormone Receptor (2002) (0)
- Chromatin. The living genome. (2002) (0)
- Chapter 3 – The Nucleus (2002) (0)
- MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes (2008) (0)
- Faculty Opinions recommendation of Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae. (2006) (0)
- Chromatin targets: reading and writing the cancer cell epigenome (2004) (0)
- Faculty Opinions recommendation of Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment. (2005) (0)
- “Designer” Cells for Cellular Immunotherapy: Zinc Finger Nuclease (ZFN) Stimulated Targeted Recombination for the Simultaneous Disruption of the Endogenous Glucocorticoid Receptor and Site-Specific Addition of the IL13-Zetakine. (2006) (0)
- Repression of vascular endothelial growth factor-A over-expression in glioblastoma cells using engineered zinc-finger transcription factors (2004) (0)
- Transcription Factors Glioblastoma Cells Using Engineered Zinc Finger Repression of Vascular Endothelial Growth Factor A in Updated (2003) (0)
- ENGINEERED ZINC FINGER PROTEINS – EDITORS OF GENOME SEQUENCE AND FUNCTION (2005) (0)
- Plant Symposia (2008) (0)
- Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis (2012) (0)
- Dr Alan P Wolffe 1959–2001 (2001) (0)
- 34 Zinc finger nucleases targeted to the m.3243A>G mutation in mitochondrial encephalomyopathy (MELAS) (2010) (0)
- Human tissue with adult stem cell properties derived from pluripotent stem cells. (2014) (0)
- Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila (2013) (0)
- 1040. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome Using Designed Zinc Finger Endonucleases (2006) (0)
- Tal-effector (tale) dna-binding polypeptides and uses thereof (2011) (0)
- TARGETED MODIFICATION OF THE RAT GENOME USING ZINC FINGER NUCLEASES (2009) (0)
- 379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification Therapies (2005) (0)
- SARS-Cov2 Clinical Diagnostics: Academic Scientists Take on the COVID-19 Pandemic (2020) (0)
- Uncoupling of Chromatin Assembly from DNA Replication in Sciara Reveals a Domain of Postreplicative Immature Chromatin (2021) (0)
- Faculty Opinions recommendation of The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. (2004) (0)
- A path to efficient gene editing (2018) (0)
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What Schools Are Affiliated With Fyodor Urnov?
Fyodor Urnov is affiliated with the following schools:
