Gideon Berke
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Education
Gideon Berke's Degrees
- PhD Education Stanford University
- Masters Education Stanford University
- Bachelors Psychology University of California, Berkeley
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(Suggest an Edit or Addition)Gideon Berke's Published Works
Published Works
- The CTL's kiss of death (1995) (554)
- Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis (2003) (396)
- The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects. (1994) (338)
- Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells (1982) (308)
- Regression of established murine carcinoma metastases following vaccination with tumour-associated antigen peptides (1995) (174)
- Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes: conjugation, killing and recycling at the single cell level (1975) (163)
- CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1997) (162)
- CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1994) (145)
- Interaction of cytotoxic T lymphocytes and target cells. (1980) (141)
- Nature of lymphocyte-tumor interaction. A general method for cellular immunoabsorption. (1973) (139)
- Cytotoxic T‐Lymphocytes How Do They Function? (1983) (109)
- CD40 Ligation Activates Murine Macrophages via an IFN-γ-Dependent Mechanism Resulting in Tumor Cell Destruction In Vitro 1 (2005) (106)
- The frequency of effector cells in populations containing cytotoxic T lymphocytes (1975) (96)
- Graft reaction in tissue culture. II. Quantification of the lytic action on mouse fibroblasts by rat lymphocytes sensitized on mouse embryo monolayers. (1969) (92)
- Synergistic Activation of Macrophages via CD40 and TLR9 Results in T Cell Independent Antitumor Effects1 (2006) (88)
- The regulation of CD95 ligand expression and function in CTL. (1998) (84)
- CELLULAR IMMUNOABSORBENTS IN TRANSPLANTATION IMMUNITY SPECIFIC IN VITRO DELETION AND RECOVERY OF MOUSE LYMPHOID CELLS SENSITIZED AGAINST ALLOGENEIC TUMORS (1972) (82)
- Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: a major role for inositol 1,4,5-trisphosphate. (1998) (82)
- Unlocking the secrets of CTL and NK cells. (1995) (76)
- Highly lytic in vivo primed cytolytic T lymphocytes devoid of lytic granules and BLT-esterase activity acquire these constituents in the presence of T cell growth factors upon blast transformation in vitro. (1988) (75)
- T-Lymphocyte-mediated cytolysis as an excitatory process of the target. I. Evidence that the target cell may be the site of Ca2+ action. (1985) (72)
- Cytotoxic T lymphocyte perforin and Fas ligand working in concert even when Fas ligand lytic action is still not detectable (2011) (71)
- In vivo CD40 ligation can induce T cell‐independent antitumor effects that involve macrophages (2006) (70)
- Cytotoxic T lymphocyte hybridomas that mediate specific tumor-cell lysis in vitro. (1981) (69)
- Tumor Immunity in Perforin-Deficient Mice: A Role for CD95 (Fas/APO-1)1 (2000) (69)
- Lymphocyte-triggered internal target disintegration (1991) (69)
- Killing mechanisms of cytotoxic lymphocytes (1997) (62)
- Contact regions of cytotoxic T lymphocyte-target cell conjugates. (1976) (62)
- Kinetic analysis of a graft reaction induced in cell culture. (1969) (60)
- Hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the Fas (CD95/Apo-1) receptor: Fas activation and apoptosis in hypoxic myocytes. (2002) (57)
- Cytotoxic lymphocytes in the absence of detectable antibody. (1973) (56)
- Are lytic granules and perforin 1 involved in lysis induced by in vivo-primed peritoneal exudate cytolytic T lymphocytes? (1987) (54)
- Tumoristatic effects of anti‐CD40 mAb‐activated macrophages involve nitric oxide and tumour necrosis factor‐α (2006) (54)
- T lymphocyte-mediated cytolysis. I. A common mechanism for target recognition in specific and lectin-dependent cytolysis. (1981) (54)
- Tumor escape from immune elimination. (1980) (51)
- CTLA-1 and CTLA-3 serine esterase transcripts are detected mostly in cytotoxic T cells, but not only and not always. (1987) (51)
- Energy requirements of the binding and lytic steps of T lymphocyte‐mediated cytolysis of leukemic cells in vitro (1975) (48)
- Mechanism of Lymphocyte‐Mediated Cytolysis The LMC Cycle and Its Role in Transplantation Immunity (1973) (47)
- Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. (1996) (46)
- T lymphocyte-mediated cytolysis. II. Role of target cell histocompatibility antigens in recognition and lysis. (1981) (42)
- Switch from perforin‐expressing to perforin‐deficient CD8+ T cells accounts for two distinct types of effector cytotoxic T lymphocytes in vivo (2009) (39)
- Immune privilege and FasL: two ways to inactivate effector cytotoxic T lymphocytes by FasL‐expressing cells (2002) (39)
- Lymphocyte‐Mediated Cytolysis (1988) (37)
- Mechanism of lymphocyte-mediated cytolysis: functional cytolytic T cells lacking perforin and granzymes. (1993) (37)
- The Fas-based mechanism of lymphocytotoxicity. (1997) (37)
- T lymphocyte-mediated cytolysis: dissociation of the binding and lytic mechanisms of the effector cell. (1978) (35)
- Peritoneal exudate lymphocyte and mixed lymphocyte culture hybridomas are cytolytic in the absence of cytotoxic cell proteinases and perforin (1992) (33)
- Clonal expansion of T cells: a cytotoxic T-cell response in vivo that involves precursor cell proliferation. (1986) (33)
- IN VITRO INDUCTION OF A HETEROGRAFT REACTION: Immunological Parameters of the Sensitization of Rat Lymphocytes Against Mouse Cells in Vitro (1971) (33)
- The cytolytic T lymphocyte and its mode of action. (1989) (31)
- Changes in fluorescence polarization of a membrane probe during lymphocyte-target cell interaction. (1978) (28)
- Monoclonal cytotoxic T lymphocyte hybridomas capable of specific killing activity, antigenic responsiveness, and inducible interleukin secretion. (1983) (27)
- The mitogenic activity of staphylococcal enterotoxin B (SEB): a monovalent T cell mitogen that stimulates cytolytic T lymphocytes but cannot mediate their lytic interaction. (1986) (27)
- A cell chip for sequential imaging of individual non-adherent live cells reveals transients and oscillations. (2009) (26)
- T-cell-mediated cytotoxicity. (1991) (26)
- Enumeration of lymphocyte‐target cell conjugates by cytofluorometry (1985) (26)
- Inhibition of lymphocyte‐mediated cytolysis by the local anesthetics benzyl and salicyl alcohol (1973) (24)
- Fluorescence polarization as an early measure of T-lymphocyte stimulation. (1997) (24)
- Localization of aggregated cell surface antigens of target cells bound to cytotoxic T lymphocytes (1975) (23)
- The use of 51Cr release as a measure of lymphocyte-mediated cytolysis in vitro. (1973) (23)
- An antigenic determinant of cytotoxic lymphocytes. (1973) (23)
- Mechanism of blocking by hyperimmune serum of lymphocyte-mediated cytolysis of allogeneic tumor cells. (1973) (21)
- Evaluation of the effects of cytochalasin B on lymphocyte-mediated cytolysis. (1973) (20)
- 51 Cr leakage from and uptake of trypan blue by target cells undergoing cell-mediated destruction. (1972) (20)
- Identification of cell surface glycoproteins by periodate-alkaline phosphatase hydrazide. (1986) (18)
- Up‐regulation of Fas (CD95) expression in tumour cells in vivo (2007) (18)
- Temperature control of lymphocyte-mediated cytotoxicity in vitro. (1973) (18)
- Effects of purified perforin and granzyme A from cytotoxic T lymphocytes on guinea pig ventricular myocytes. (1994) (18)
- Fluorescence depolarization as an early measure of T lymphocyte stimulation. (1997) (17)
- Possible role of nucleus-membrane interaction in capping of surface membrane receptors. (1976) (17)
- Cardiac dysfunction in murine autoimmune myocarditis. (1999) (16)
- Selective binding of concanavalin A to target cell major histocompatibility antigens is required to induce nonspecific conjugation and lysis by cytolytic T lymphocytes in lectin-dependent cytotoxicity. (1984) (16)
- The role of cytotoxic T lymphocyte projections in target cell lysis. (1981) (16)
- Debate: the mechanism of lymphocyte-mediated killing. Lymphocyte-triggered internal target disintegration. (1991) (16)
- Graft reaction in tissue culture. 3. Effect of phytohaemagglutinin. (1969) (16)
- T lymphocyte-mediated cytolysis - a comprehensive theory. I. The mechanism of CTL-mediated cytolysis. (1982) (15)
- Interaction of cytotoxic T lymphocytes and guinea pig ventricular myocytes. Pharmacological modulation by blocking K+ currents in cytotoxic T lymphocytes. (1996) (15)
- Involvement of the IP3 cascade in the damage to guinea-pig ventricular myocytes induced by cytotoxic T lymphocytes (1997) (15)
- Graft reaction in tissue culture by normal rat lymphocytes. (1969) (14)
- The lysis of cytotoxic T lymphocytes and their blasts by cytotoxic T lymphocytes. (1990) (14)
- Tumor cell destruction by cytotoxic T lymphocytes: the basis of reduced antitumor cell activity in syngeneic hosts. (1981) (14)
- PELs and the Perforin and Granzyme Independent Mechanism of CTL‐mediated Lysis (1995) (12)
- Cell surface glycoproteins of cytotoxic T lymphocytes induced in vivo and in vitro. (1981) (12)
- Macromolecular synthesis during the sensitization of rat lymphcytes on mouse fibroblasts in vitro. (1971) (12)
- Modulation of cell-mediated cytotoxicity function after alteration of fatty acid composition in vitro. (1984) (12)
- Competitive inhibition of cytotoxic T lymphocyte-target cell conjugation. A direct evaluation of membrane antigens involved in cell-mediated immunity. (1979) (12)
- Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef (2018) (11)
- Fas ( CD 95 / Apo-1 ) – Mediated Damage to Ventricular Myocytes Induced by Cytotoxic T Lymphocytes From Perforin-Deficient Mice A Major Role for Inositol 1 , 4 , 5-Trisphosphate (1998) (11)
- Immune cytolysis viewed as a stimulatory process of the target. (1985) (11)
- IS THE PRESENCE OF SEROLOGICALLY DEFINED TARGET CELL ANTIGENS SUFFICIENT FOR BINDING OF CYTOTOXIC T LYMPHOCYTES?1 (1978) (11)
- Induction of cell-mediated immunity against leukemia EL4 in C57BL mice. (1973) (10)
- Immunoglobulins detected in cell populations involved in graft rejection. (1977) (10)
- Receptors for antigen on lymphoid cells. I. Immunoadsorption of plaque-forming cells to poly-L-lysine-fixed antigen monolayers. (1974) (10)
- An appraisal of some current thoughts on cytolytic T-lymphocyte killing mechanisms. (1987) (10)
- Simultaneous monitoring of binding to and activation of tumor-specific T lymphocytes by peptide-MHC. (2003) (10)
- Prelytic reduction of high-energy phosphates induced by antibody and complement in nucleated cells. 31P-NMR study. (1984) (9)
- Immunological rejection of heart transplant: how lytic granules from cytotoxic T lymphocytes damage guinea pig ventricular myocytes (1992) (9)
- Activity of tumor-associated lymphoid cells at short intervals after administration of irradiated syngeneic and allogeneic tumor cells. (1977) (9)
- Channel formation and [Ca2+]i accumulation induced by perforin N-terminus peptides: comparison with purified perforin and whole lytic granules. (1997) (9)
- Studies on the nature of messenger RNA in phytohemagglutinin-stimulated rat lymphocytes. (1971) (9)
- Mechanisms whereby Lytic Granules from Cytotoxic T Lymphocytes Damage Guinea Pig Ventricular Myocytes (1993) (8)
- Tumor sensitivity to anti-cancer drugs predicted by changes in fluorescence intensity and polarization in vitro. (2002) (8)
- How T lymphocytes kill infected cells. (1985) (8)
- T-lymphocyte-mediated cytolysis: contribution of intracellular components to target cell susceptibility. (1977) (8)
- Multiple mechanisms of lymphocyte-mediated killing. (1988) (8)
- Calcium channel blockers modify electrophysiological effects induced by lytic granules from cytotoxic T lymphocytes in guinea pig ventricular myocytes. (1994) (7)
- A rapid method for generating cytotoxic effector cells in vivo. (1979) (7)
- T lymphocyte-mediated cytolysis. III. Delineation of mechanisms whereby mitogenic and non-mitogenic lectins mediate lymphocyte-target interaction. (1983) (7)
- Delineation of tissue damage mechanisms in experimental autoimmune encephalomyelitis (EAE). I. Cell detachment and lysis induced by encephalitogenic CD4+ T lymphocytes. (1992) (7)
- Maturation of cytolytic T lymphocytes. (1986) (7)
- Delineation of tissue damage mechanisms in experimental autoimmune encephalomyelitis (EAE). II. Characteristics of astrocyte detachment mediated by myelin basic protein (MBP) specific CD4+ T lymphocytes. (1992) (6)
- Effects of heparin and benzyl alcohol on lymphocyte-mediated cytotoxicity in vitro. (1973) (6)
- Mouse Cell Destruction by in vitro Sensitized Rat Lymphoid Cells (1971) (6)
- Functional characterization of membrane components of cytotoxic peritoneal exudate T lymphocytes. I. Search for T cell receptor activity in lymphocyte membrane fractions. (1974) (6)
- Functional cytotoxic T lymphocyte hybridomas. (1981) (6)
- Graft reaction in cell culture. (1969) (5)
- NATURE OF LYMPHOCYTE-TUMOR INTERACTION (1973) (5)
- Specific lysis of antigenically irrelevant cells by cytotoxic T lymphocytes upon insertion of appropriate antigens into the target cell plasma membranes. (1983) (5)
- THE INFLUENCE OF NORMAL SERUM COMPONENTS ON LYMPHOCYTE-MEDIATED CYTOLYSIS IN VITRO (1974) (5)
- Cytotoxic T cell hybridomas: generation and characterization. (1982) (5)
- Connexin 37 gene is not mutated in lung carcinomas 3LL and CMT. (2003) (5)
- Serum factors in lymphocyte proliferation. I. The requirement for serum in mixed lymphocyte reactions. (1973) (5)
- Lytic reaction of in vivo primed peritoneal exudate CTL. Induction of high-conductance single channels in the target cell membrane. (1995) (4)
- Memory CTL-hybridoma: a model system to analyze the anamnestic response of cytolytic T lymphocytes. (1984) (4)
- Activation of influenza-specific memory cytotoxic T lymphocytes by Concanavalin A stimulation. (1998) (4)
- Mechanisms whereby cytotoxic T lymphocytes damage guinea-pig ventricular myocytes in vitro (1994) (4)
- Mechanism of action of cytotoxic T-cells (1983) (4)
- CELLULAR IMMUNOABSORBENTS IN TRANSPLANTATION IMMUNITY (1972) (3)
- Tumor immunity in the peritoneal cavity. (1980) (3)
- Peripheral blood mononuclear cells of HIV‐infected patients contain CD8 T cells that form conjugates with and kill HIV‐infected autologous CD4 T cells (2015) (3)
- Hyperthermia and formaldehyde can dissociate the binding and killing activities of cytolytic T lymphocytes. (1979) (3)
- PERITONEAL LYMPHOID E~FECI'OR CELLS FROM BALB/c MICE IMMUNE TO EL4 LEUKOSIS* (1972) (3)
- Retracted Correction: CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1998) (3)
- Partial definition of serum factors required for lymphocyte-mediated cytotoxicity. Abstr. (1973) (3)
- A Common Role for Target Cell Histocompatibility Antigens in Both Nonspecific and Specific T Lymphocyte‐Mediated Cytolysis (1982) (3)
- The pathway of lectin-mediated lymphocytotoxicity by Con A-coupled Sepharose beads. (1984) (3)
- RECENT ADVANCES AND QUESTIONS IN LYMPHOCYTOTOXICITY (1977) (2)
- Antigen/mitogen induced cytolytic activity and IL-2 secretion in memory-like CTL-hybridomas. (1985) (2)
- Localization of 51 Cr-labeled sensitized lymphocytes at the allograft region: a possible diagnostic test in organ transplantation. (1972) (2)
- T lymphocyte-mediated cytolysis - a comprehensive theory. II. Lytic vs. nonlytic interactions of T lymphocytes. (1982) (2)
- Cellular activities necessary for specific binding of cytotoxic T lymphocytes and target cells. (1979) (2)
- Interaction of periodate‐oxidized target cells and cytolytic T lymphocytes: a model system of “polyclonal MHC recognition” (1986) (2)
- Lymphocyte-target cell conjugation: membrane receptors for alloantigens. (1976) (2)
- ENUCLEATED CYTOTOXIC T LYMPHOCYTES BIND SPECIFICALLY TO TARGET CELLS IN VITRO (1980) (2)
- Basic Immunobiology: A Primer (2007) (1)
- Proceedings: Cell-mediated anti-leukemic cell immunity in C57BL/6 mice injected with the radiation leukemic virus. (1975) (1)
- Immunobiology and Molecular Characteristics of Peritoneal Exudate Cytotoxic T Lymphocytes (PEL), Their In Vivo IL-2-Dependent Blasts and IL-2-Independent Cytolytic Hybridomas (1993) (1)
- IL-2 Mediated Induction of Lytic Granules, Perforin, and BLT-Esterase in Potent, Granule-Free Cytolytic T Lymphocytes Indicates an Alternative Function of Lytic Granules (1988) (1)
- Effect of oxidation on the conformation of cell surface H-2 antigens detected by monoclonal antibodies. (1987) (1)
- Abnormal glutathione sulfate levels after interleukin 6 treatment tumor-induced cachexia (1996) (1)
- Cytotoxic T Lymphocytes: Mechanism of Action and Role in Allograft Rejection (2004) (1)
- Anti-CD40 Monoclonal Antibody and CpG-ODN Synergize in Macrophage Activation: Implication for Cancer Immunotherapy (2004) (1)
- Redistribution of membrane proteins in enucleated cells. Abstr. (1976) (1)
- The function of lytic granules in tumor therapy induced by IL-2 activated killer lymphocytes (1993) (0)
- Cytotoxic T Lymphocytes: Generation and Cellular Properties (2007) (0)
- Gene therapy and peptide therapy of tumor metastasis (2007) (0)
- Rapid tumor cell destruction in vitro by immune non-adherent peritoneal cells. Abstr. (1972) (0)
- Ninth UICC Training Course in Cancer Research, The Weizmann Institute of Science, Rehovot, Israel 10‐21 October, 1982 (1982) (0)
- Direct Contact of Cytotoxic T-Lymphocyte Receptors with Target Cell Membrane Determinants Induces a Prelytic Rise of [Ca2+]i in the Target That Triggers Disintegration (1993) (0)
- 635. In HIV-Infected Patients Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef (2018) (0)
- Cytotoxicity Assays: Killer Lymphocytes in Cancer (2005) (0)
- A Role for CD 95 ( Fas / APO-1 ) Tumor Immunity in Perforin-Deficient Mice : Orda and Gideon (2000) (0)
- The Role of Cytotoxicity in Allograft Rejection In Vivo (2007) (0)
- Cytotoxic T Lymphocytes: Target Cell Recognition and Binding (2007) (0)
- POLAR EVENTS IN T LYMPHOCYTE MEDIATED LYSIS: UNIDIRECTIONAL KILLING DURING BIDIRECTIONAL INTERACTION OF CYTOTOXIC T LYMPHOCYTES (1979) (0)
- Common CASR variants in Hungarian chronic pancreatitis patients (2020) (0)
- Multiple mechanisms of lymphocyte-mediated (1988) (0)
- Discordance of alloimmune cellular and humoral lysis against antigens inserted into the plasma membranes of antigenically irrelevant target cells. (1983) (0)
- EAE: Detachment of astrocytes with or without subsequent lysis induced by encephalitogenic CD4+ T lymphocytes (1991) (0)
- Cytotoxic t lymphocyte-target cell interaction. Abstr. (1976) (0)
- Homeostasis, Memory and CTL Vaccines (2007) (0)
- The cytolytic T lymphocyte--reply to commentary. (1989) (0)
- Diagnostic accuracy of different modalities in cystic fibrosis-related liver disease: A diagnostic accuracy network meta-analysis (2020) (0)
- Common CASR polymorphisms do not increase chronic pancreatitis risk (2021) (0)
- BINDING OF IMMUNOGLOBULIN-BEARING LYMPHOID CELLS TO ALLOGENEIC AND SYNGENEIC TARGET CELLS (1977) (0)
- R E J E C T I O N OF ASCITES TUMOR ALLOGRAFTS I. ISOLATION, CHARACTERIZATION, AND IN VITRO REACTIVITY OF PERITONEAL LYMPHOID E~FECI'OR CELLS FROM BALB/c MICE IMMUNE TO EL4 LEUKOSIS* BY GIDEON BERKE,~ (1972) (0)
- Cytotoxic T Lymphocytes: Target Cell Killing: Molecular mechanisms (2007) (0)
- IMMUNITY SPECIFIC IN VITRO DELETION AND RECOVERY OF ),lOUSE LYMPHOID CELLS SENSITIZED AGAINST ALLOGENEIC TUMORS* (1972) (0)
- Cytotoxicity in Immune Defenses Against Intracellular Parasites (2007) (0)
- Cytotoxic T lymphocyte hybridomas that mediate specific tumor-cell lysis in vitro ( allogeneic murine cytotoxic T lymphocytes / fusion / clones / immune killing ) (0)
- Cytotoxic T Lymphocytes: Target Cell Killing: Cellular Parameters (2007) (0)
- Surface membrane components of cytotoxic T lymphocytes. (1979) (0)
- DEVOID OF CONSTITUENTS IN THE PRESENCE OF T CELL GROWTH FACTORS UPON BLAST TRANSFORMATION IN VITRO' LYTIC GRANULES AND BLT-ESTERASE ACTIVITY ACQUIRE THESE (2001) (0)
- Independent Antitumor Effects CD40 and TLR9 Results in T Cell Synergistic Activation of Macrophages via (2005) (0)
- Bicarbonate defective CFTR variants in chronic pancreatitis: A meta-analysis (2021) (0)
- and Function in CTL The Regulation of CD95 Ligand Expression (1998) (0)
- Metabolic depletion preceding cytolysis induced by antibody and complement as revealed by 31P-NMR spectroscopy. (1986) (0)
- Macrophages are Essential for Growth Control of Weakly Immunogenic Tumors During Immunotherapy With CpG (2005) (0)
- Killer Cells and Cancer (2007) (0)
- Innate Cell-mediated Immunity (2007) (0)
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