George E. Bigelow
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Biology
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(Suggest an Edit or Addition)George E. Bigelow's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. (1997) (756)
- Clinical pharmacology of buprenorphine: Ceiling effects at high doses (1994) (716)
- College on Problems of Drug Dependence taskforce on prescription opioid non-medical use and abuse: position statement. (2003) (465)
- Moderate- vs high-dose methadone in the treatment of opioid dependence: a randomized trial. (1999) (422)
- A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence. (2000) (386)
- An automated version of the digit symbol substitution test (DSST) (1982) (364)
- Acute administration of buprenorphine in humans: partial agonist and blockade effects. (1995) (282)
- A clinical trial of buprenorphine: Comparison with methadone in the detoxification of heroin addicts (1988) (277)
- Comparison of buprenorphine and methadone in the treatment of opioid dependence. (1994) (270)
- Dose-Response Effects of Methadone in the Treatment of Opioid Dependence (1993) (248)
- QT-interval effects of methadone, levomethadyl, and buprenorphine in a randomized trial. (2007) (243)
- Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans (2001) (227)
- Buprenorphine: dose-related blockade of opioid challenge effects in opioid dependent humans. (1988) (226)
- Facilitation of human tobacco self-administration by ethanol: a behavioral analysis. (1976) (204)
- Voucher-based reinforcement of cocaine abstinence in treatment-resistant methadone patients: effects of reinforcement magnitude (1999) (198)
- A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence. (1995) (193)
- Providing medical care to methadone clinic patients: referral vs on-site care. (1994) (188)
- Principles of initial experimental drug abuse liability assessment in humans. (2003) (186)
- Primary outcome indices in illicit drug dependence treatment research: systematic approach to selection and measurement of drug use end-points in clinical trials. (2012) (179)
- A reinforcement-based therapeutic workplace for the treatment of drug abuse: six-month abstinence outcomes. (2001) (169)
- Effects of buprenorphine/naloxone in opioid-dependent humans (2001) (169)
- Guidelines and methodological reviews concerning drug abuse liability assessment. (2003) (162)
- Human coffee drinking: reinforcing and physical dependence producing effects of caffeine. (1986) (157)
- Buprenorphine implants for treatment of opioid dependence: a randomized controlled trial. (2010) (154)
- Buprenorphine versus methadone in the treatment of opioid dependence: self-reports, urinalysis, and addiction severity index. (1996) (149)
- Antisocial personality disorder and HIV infection among intravenous drug abusers. (1993) (145)
- Subjective and discriminative effects of drugs. (1991) (141)
- Acute Effects of Smoked and Vaporized Cannabis in Healthy Adults Who Infrequently Use Cannabis (2018) (136)
- Acute physical dependence in man: effects of naloxone after brief morphine exposure. (1988) (134)
- Concurrent validation of the Clinical Opiate Withdrawal Scale (COWS) and single-item indices against the Clinical Institute Narcotic Assessment (CINA) opioid withdrawal instrument. (2009) (133)
- Effect of intravenous injection speed on responses to cocaine and hydromorphone in humans (2001) (132)
- Extended‐release injectable naltrexone for opioid use disorder: a systematic review (2018) (125)
- Site of opioid action in the human brain: mu and kappa agonists' subjective and cerebral blood flow effects. (1998) (123)
- Drug preference in humans: double-blind choice comparison of pentobarbital, diazepam and placebo. (1980) (122)
- Pharmacokinetic Profile of Oral Cannabis in Humans: Blood and Oral Fluid Disposition and Relation to Pharmacodynamic Outcomes. (2017) (121)
- Effects of naltrexone on response to intravenous cocaine, hydromorphone and their combination in humans. (1996) (118)
- Methadone dose and treatment outcome. (1993) (116)
- Drug discrimination in human postaddicts: agonist-antagonist opioids. (1989) (113)
- Enadoline and butorphanol: evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans. (2001) (111)
- Early Treatment Time Course of Depressive Symptoms in Opiate Addicts (1991) (107)
- Cost Factors Controlling Alcoholic Drinking (1972) (107)
- Methadone doses of 100 mg or greater are more effective than lower doses at suppressing heroin self-administration in opioid-dependent volunteers. (2005) (106)
- Fluoxetine Alters the Effects of Intravenous Cocaine in Humans (1994) (106)
- Effect of methadone dose contingencies on urinalysis test results of polydrug-abusing methadone-maintenance patients. (1986) (106)
- Task Force 1: Classification and assessment of smoking behavior. (1986) (102)
- Validity of patients' self-reported drug use as a function of treatment status. (1992) (102)
- Alcoholism among methadone patients: a specific treatment method. (1973) (102)
- A reinforcement-based therapeutic workplace for the treatment of drug abuse: three-year abstinence outcomes. (2002) (102)
- Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo. (1979) (101)
- Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial (2018) (100)
- Voucher-based reinforcement of opiate plus cocaine abstinence in treatment-resistant methadone patients: effects of reinforcer magnitude. (2001) (100)
- Contingency management in methadone maintenance: effects of reinforcing and aversive consequences on illicit polydrug use. (1988) (99)
- Smoking following myocardial infarction: a critical review of the literature. (1984) (98)
- Acute opioid physical dependence in postaddict humans: naloxone dose effects after brief morphine exposure. (1989) (98)
- Effects of buprenorphine and methadone in methadone-maintained subjects (1995) (97)
- Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers (2000) (96)
- Buprenorphine treatment of opioid dependence: clinical trial of daily versus alternate-day dosing. (1995) (94)
- Differential effects of diazepam and pentobarbital on mood and behavior. (1983) (93)
- A randomized trial of long-term reinforcement of cocaine abstinence in methadone-maintained patients who inject drugs. (2004) (91)
- Comparison of diazepam and oxazepam: preference, liking and extent of abuse. (1984) (91)
- Contingent reinforcement for carbon monoxide reduction: within-subject effects of pay amount. (1984) (91)
- Classification and assessment of smoking behavior. (1986) (90)
- Contingent methadone delivery: effects on illicit-opiate use. (1986) (89)
- Acute effects of buprenorphine, hydromorphone and naloxone in methadone-maintained volunteers. (1992) (89)
- High-dose methadone produces superior opioid blockade and comparable withdrawal suppression to lower doses in opioid-dependent humans (2002) (88)
- Contingent reinforcement for benzodiazepine-free urines: evaluation of a drug abuse treatment intervention. (1982) (88)
- Repeated administration of the D1/5 antagonist ecopipam fails to attenuate the subjective effects of cocaine (2001) (87)
- Intravenous drug abusers with antisocial personality disorder: increased HIV risk behavior. (1990) (85)
- Characteristics of older opioid maintenance patients. (2005) (83)
- Effects of cocaine alone and in combination with bromocriptine in human cocaine abusers. (1992) (83)
- Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans. (1996) (83)
- Contingent payment for carbon monoxide reduction: Effects of pay amount (1983) (81)
- Reducing drug use among methadone maintenance clients: contingent reinforcement for morphine-free urines. (1980) (78)
- Antisocial behavior of intravenous drug abusers: implications for diagnosis of antisocial personality disorder. (1992) (78)
- A behavioral treatment of alcoholic methadone patients. (1978) (77)
- Predictors of outcome in LAAM, buprenorphine, and methadone treatment for opioid dependence. (2005) (77)
- Theoretical and empirical foundations of contingency management treatments for drug abuse. (1999) (77)
- Sublingual buprenorphine/naloxone precipitated withdrawal in subjects maintained on 100mg of daily methadone. (2007) (77)
- Buprenorphine versus methadone in the treatment of opioid-dependent cocaine users (1994) (75)
- Reinforcing effects of caffeine in coffee and capsules. (1989) (75)
- Contingent payment procedures for smoking reduction and cessation. (1986) (74)
- Behavioral contingencies improve counseling attendance in an adaptive treatment model. (2004) (74)
- Effects of cocaine alone and in combination with mazindol in human cocaine abusers. (1993) (74)
- Physical dependence potential of daily tramadol dosing in humans (2010) (74)
- Voucher-based reinforcement of attendance by unemployed methadone patients in a job skills training program. (1996) (74)
- Diazepam and methadone interactions in methadone maintenance (1984) (73)
- Buprenorphine effects in methadone-maintained volunteers: effects at two hours after methadone. (1995) (73)
- Antisocial Personality Disorder among Drug Abusers: Relations to Other Personality Diagnoses and the Five-Factor Model of Personality (1993) (72)
- Medication take-home as a reinforcer in a methadone maintenance program. (1977) (71)
- Alcohol and secobarbital effects as a function of familial alcoholism: extended intoxication and increased withdrawal effects. (1991) (70)
- Relative bioavailability of different buprenorphine formulations under chronic dosing conditions. (2004) (69)
- Clustering of multiple substance use and psychiatric diagnoses in opiate addicts. (1991) (69)
- Effects of sublingually given naloxone in opioid-dependent human volunteers. (1990) (69)
- Buprenorphine alone and in combination with naloxone in non-dependent humans. (1992) (65)
- Employment-based reinforcement of adherence to an FDA approved extended release formulation of naltrexone in opioid-dependent adults: a randomized controlled trial. (2012) (65)
- Antagonist effects of nalbuphine in opioid-dependent human volunteers. (1989) (65)
- Differential naltrexone antagonism of hydromorphone and pentazocine effects in human volunteers. (1993) (64)
- Alcohol and marijuana: Comparative dose effect profiles in humans (1988) (64)
- Human cigarette smoking: manipulation of number of puffs per bout, interbout interval and nicotine dose. (1982) (64)
- Acute opioid physical dependence in humans: Effect of naloxone at 6 and 24 hours postmorphine (1990) (63)
- Three-choice drug discrimination in opioid-dependent humans: hydromorphone, naloxone and saline. (1987) (62)
- Choosing to take cocaine in the human laboratory: effects of cocaine dose, inter-choice interval, and magnitude of alternative reinforcement. (2003) (61)
- Discriminative stimulus and subjective effects of opioids with mu and kappa activity: data from laboratory animals and human subjects (1997) (61)
- Contingent reinforcement for reduced carbon monoxide levels in cigarette smokers. (1982) (60)
- Butorphanol-precipitated withdrawal in opioid-dependent human volunteers. (1988) (59)
- Alcohol expectancies and changes in beer consumption of first-year college students. (1995) (59)
- Buprenorphine and naloxone alone and in combination in opioid-dependent humans (1988) (59)
- Dose-related efficacy of levomethadyl acetate for treatment of opioid dependence. A randomized clinical trial. (1997) (59)
- Non-smoker exposure to secondhand cannabis smoke. I. Urine screening and confirmation results. (2015) (58)
- Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users. (2020) (58)
- Validity of intravenous drug abusers' self-reported changes in HIV high-risk drug use behaviors. (1995) (57)
- Maintaining disulfiram ingestion among outpatient alcoholics: a security-deposit contingency contracting procedure. (1976) (57)
- Discrimination of agonist-antagonist opioids in humans trained on a two-choice saline-hydromorphone discrimination. (1992) (56)
- Voucher-based reinforcement of opiate abstinence during methadone detoxification. (2002) (56)
- Alcoholic drinking: suppression by a brief time-out procedure. (1974) (55)
- Modulation of intravenous cocaine effects by chronic oral cocaine in humans (2000) (55)
- Human coffee drinking: manipulation of concentration and caffeine dose. (1986) (55)
- Employment-based reinforcement of adherence to depot naltrexone in unemployed opioid-dependent adults: a randomized controlled trial. (2011) (54)
- Oral methadone self‐administration: Effects of dose and alternative reinforcers (1983) (54)
- The effects of buprenorphine in buprenorphine-maintained volunteers (1997) (53)
- Contingency management in a methadone maintenance program: availability of reinforcers. (1978) (53)
- Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming (2004) (53)
- A therapeutic workplace for the long-term treatment of drug addiction and unemployment: eight-year outcomes of a social business intervention. (2014) (53)
- Acute Pharmacokinetic Profile of Smoked and Vaporized Cannabis in Human Blood and Oral Fluid. (2019) (53)
- The effects of contingent payment and frequent workplace monitoring on smoking abstinence. (1989) (52)
- Does this patient really want treatment? Factors associated with baseline and evolving readiness for change among hospitalized substance using adults interested in treatment. (2006) (52)
- Experimental models for the modification of human drug self-administration: Methodological developments in the study of ethanol self-administration by alcoholics. (1975) (52)
- Non-smoker exposure to secondhand cannabis smoke II: Effect of room ventilation on the physiological, subjective, and behavioral/cognitive effects. (2015) (52)
- Repeated dosing with oral cocaine in humans: assessment of direct effects, withdrawal, and pharmacokinetics. (2009) (52)
- Open-label trial of an injection depot formulation of buprenorphine in opioid detoxification. (2004) (51)
- Opioid Overdose Experience, Risk Behaviors, and Knowledge in Drug Users from a Rural versus an Urban Setting. (2016) (51)
- Factors identifying high-frequency and low-frequency health service utilization among substance-using adults. (2007) (51)
- Opioid drug discrimination in humans: stability, specificity and relation to self-reported drug effect. (1989) (50)
- An injection depot formulation of buprenorphine: extended bio-delivery and effects. (2006) (50)
- Blockade of hydromorphone effects by buprenorphine/naloxone and buprenorphine (2002) (50)
- Abstinence or moderation? Choice by alcoholics. (1972) (50)
- The brief abstinence test: voucher-based reinforcement of cocaine abstinence. (2000) (49)
- Induction of Opioid‐Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone Soluble‐Films (2011) (49)
- Contingency management interventions: effects on treatment outcome during methadone detoxification. (1984) (49)
- Contingent reinforcement for reduced breath carbon monoxide levels: target-specific effects on cigarette smoking. (1985) (49)
- Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations (2012) (48)
- Rapid resumption of cigarette smoking following myocardial infarction: inverse relation to MI severity. (1982) (47)
- Suppression of ethanol self-administration in alcoholics by contingent time-out from social interactions. (1974) (47)
- Buprenorphine, morphine and naloxone effects during ascending morphine maintenance in humans. (1996) (47)
- Abstinence-contingent reinforcement and engagement in non-drug-related activities among illicit drug abusers. (2008) (46)
- The health encounter as a treatable moment for homeless substance-using adults: the role of homelessness, health seeking behavior, readiness for behavior change and motivation for treatment. (2008) (46)
- Physical health as a motivator for substance abuse treatment among medically ill adults: is it enough to keep them in treatment? (2006) (46)
- Nonsmoker Exposure to Secondhand Cannabis Smoke. III. Oral Fluid and Blood Drug Concentrations and Corresponding Subjective Effects. (2015) (45)
- Modest opioid withdrawal suppression efficacy of oral tramadol in humans (2007) (45)
- A validated liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry method for quantitation of cocaine and benzoylecgonine in human plasma. (2001) (45)
- Contingency management approaches to drug self-administration and drug abuse: efficacy and limitations. (1981) (45)
- Contingency management in methadone treatment: the case for positive incentives. (1993) (45)
- Topiramate for cocaine dependence during methadone maintenance treatment: a randomized controlled trial. (2014) (45)
- Reducing benzodiazepine self-administration with contingent reinforcement. (1979) (44)
- Familial density of alcoholism: effects on psychophysiological responses to ethanol. (1991) (44)
- Drug discrimination assessment of agonist-antagonist opioids in humans: a three-choice saline-hydromorphone-butorphanol procedure. (1994) (43)
- Human sedative self-administration: effects of interingestion interval and dose. (1976) (43)
- Discriminative Stimulus Effects of Tramadol in Humans (2011) (42)
- Pharmacological influences upon human ethanol self-administration. (1977) (41)
- Discrimination of butorphanol and nalbuphine in opioid-dependent humans (1990) (41)
- Effect of ethanol self-administration on choice behavior: Money vs. socializing (1975) (40)
- Absence of acute cocaine interactions with the MAO-B inhibitor selegiline. (1995) (40)
- Alcohol and drug use by college males as a function of family alcoholism history. (1990) (40)
- Psychiatric symptoms in polysubstance abusers: relationship to race, sex, and age. (1995) (40)
- Alcohol and secobarbital effects as a function of familial alcoholism: acute psychophysiological effects. (1990) (40)
- Employment-based reinforcement of adherence to oral naltrexone treatment in unemployed injection drug users. (2013) (40)
- Cocaine abuse versus cocaine dependence: cocaine self-administration and pharmacodynamic response in the human laboratory. (2010) (39)
- Effect of flupenthixol on subjective and cardiovascular responses to intravenous cocaine in humans. (2001) (39)
- Depth of sedation as an interventional target to reduce postoperative delirium: mortality and functional outcomes of the Strategy to Reduce the Incidence of Postoperative Delirium in Elderly Patients randomised clinical trial (2019) (39)
- Effects of repeated tramadol and morphine administration on psychomotor and cognitive performance in opioid-dependent volunteers. (2010) (38)
- Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial (2017) (38)
- A randomized controlled trial of fluoxetine in the treatment of cocaine dependence among methadone-maintained patients. (2011) (38)
- Precipitated withdrawal by pentazocine in methadone-maintained volunteers. (1993) (37)
- Controlled opioid withdrawal evaluation during 72 h dose omission in buprenorphine-maintained patients. (1997) (37)
- Contingency management in cocaine abusers: a dose-effect comparison of goods-based versus cash-based incentives. (2007) (36)
- Competing motivations: drug reinforcement vs non-drug reinforcement (1998) (36)
- Human drug abuse liability assessment: opioids and analgesics. (1991) (36)
- Evaluation of an injection depot formulation of buprenorphine: placebo comparison. (2004) (36)
- Effects of agonist-antagonist opioids in humans trained in a hydromorphone/not hydromorphone discrimination. (2000) (35)
- Opioid challenge evaluation of blockade by extended-release naltrexone in opioid-abusing adults: dose-effects and time-course. (2012) (35)
- Brief Opioid Overdose Knowledge (BOOK): A Questionnaire to Assess Overdose Knowledge in Individuals Who Use Illicit or Prescribed Opioids (2016) (35)
- Reinforcement of drug abstinence: a behavioral approach to drug abuse treatment. (1979) (35)
- Enhancement of cocaine's abuse liability in methadone maintenance patients (2005) (35)
- Relative abuse liability of diazepam and oxazepam: Behavioral and subjective dose effects (1984) (34)
- Acute opioid physical dependence in humans: effect of varying the morphine-naloxone interval. I. (1989) (34)
- HIV risk behaviors during pharmacologic treatment for opioid dependence: A comparison of levomethadyl acetate hydrochloride, buprenorphine, and methadone (2006) (34)
- Pharmacokinetics and Pharmacodynamics of Methadone Enantiomers After Coadministration with Amprenavir in Opioid‐Dependent Subjects (2004) (33)
- Disulfiram maintenance employee alcoholism treatment: a three-phase evaluation. (1979) (33)
- Transdermal selegiline and intravenous cocaine: safety and interactions (2004) (33)
- Human social conversation: Effects of ethanol, secobarbital and chlorpromazine (1981) (33)
- Smoking during pregnancy: Reduction via objective assessment and directive advice (1991) (32)
- Buprenorphine Reduces Cerebral Glucose Metabolism in Polydrug Abusers (1994) (31)
- Pharmacological advances in addiction treatment. (1985) (31)
- Incongruity between occupational interests and academic skills in drug abusing women. (1995) (31)
- Evaluation of the mu and kappa opioid actions of butorphanol in humans through differential naltrexone blockade (2007) (31)
- Intravenous and Oral l-α-Acetylmethadol: Pharmacodynamics and Pharmacokinetics in Humans (1998) (31)
- Relative abuse liability of lorazepam and diazepam: an evaluation in 'recreational' drug users. (1988) (31)
- Drug discrimination in human post-addicts: agonist/antagonist opioids. (1988) (30)
- A randomized clinical trial of a Therapeutic Workplace for chronically unemployed, homeless, alcohol-dependent adults. (2011) (30)
- Monetary incentives to reinforce engagement and achievement in a job-skills training program for homeless, unemployed adults. (2013) (30)
- Phenylpropanolamine: Effects on Subjective and Cardiovascular Variables at Recommended Over‐the‐Counter Dose Levels (1987) (30)
- Drug-produced changes in human social behavior: Facilitation by d-amphetamine (1977) (30)
- Induction with levomethadyl acetate: safety and efficacy. (1998) (29)
- Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts. (1987) (29)
- Randomized controlled trial of a computerized opioid overdose education intervention (2017) (29)
- IDENTIFYING TYPES OF DRUG INTOXICATION: LABORATORY EVALUATION OF A SUBJECT-EXAMINATION PROCEDURE (1985) (29)
- Psychiatric distress in antisocial drug abusers: relation to other personality disorders. (1994) (28)
- Human abuse liability assessment of oxycodone combined with ultra-low-dose naltrexone (2010) (28)
- Acute physical dependence in humans: repeated naloxone-precipitated withdrawal after a single dose of methadone. (1991) (27)
- Behavioral Treatment of Alcohol Problems (1980) (27)
- Effects associated with double-blind omission of buprenorphine/naloxone over a 98-h period (2006) (27)
- The Effect of Integrated Medical-Substance Abuse Treatment During an Acute Illness on Subsequent Health Services Utilization (2007) (27)
- Urinary Pharmacokinetic Profile of Cannabinoids Following Administration of Vaporized and Oral Cannabidiol and Vaporized CBD-Dominant Cannabis. (2019) (27)
- Assessment of opioid partial agonist activity with a three-choice hydromorphone dose-discrimination procedure. (1999) (26)
- Pharmacodynamic dose effects of oral cannabis ingestion in healthy adults who infrequently use cannabis. (2020) (26)
- Cognitive performance in methadone maintenance patients: effects of time relative to dosing and maintenance dose level. (2014) (26)
- Evaluation of the effects of lofexidine and clonidine on naloxone-precipitated withdrawal in opioid-dependent humans. (2003) (25)
- Relationship of Social Factors to Ethanol Self-Administration in Alcoholics (1978) (25)
- Evaluation of a transdermal buprenorphine formulation in opioid detoxification. (2007) (24)
- Comparing the physiological and subjective effects of self-administered vs yoked cocaine in humans (2006) (24)
- Effects of response requirement upon human sedative self-administration and drug-seeking behavior (1976) (24)
- HIV risk behavior in drug users: increased blood "booting" during cocaine injection. (1992) (24)
- An experimental approach to treating chronic alcoholism: a case study and one-year follow-up. (1973) (24)
- Opioid discrimination in humans: discriminative and subjective effects of progressively lower training dose (1998) (24)
- Opioid miosis: effects of lighting intensity and monocular and binocular exposure. (1993) (24)
- Managing acutely ill substance-abusing patients in an integrated day hospital outpatient program: medical therapies, complications, and overall treatment outcomes. (2006) (23)
- Clinical pharmacology of buprenorphine (1995) (23)
- Smoking topography and carbon monoxide levels in smokers. (1985) (23)
- Opioid Overdose History, Risk Behaviors, and Knowledge in Patients Taking Prescribed Opioids for Chronic Pain (2016) (23)
- Opioid detoxification via single 7-day application of a buprenorphine transdermal patch: an open-label evaluation (2008) (23)
- Relative potency of levo-alpha-acetylmethadol and methadone in humans under acute dosing conditions. (1999) (22)
- Assessment of agonist and antagonist effects of tramadol in opioid-dependent humans. (2006) (22)
- Acute effects of intramuscular and sublingual buprenorphine and buprenorphine/naloxone in non-dependent opioid abusers (2010) (22)
- Evaluation of Potential Pharmacotherapies: Response to Cocaine Challenge in the Human Laboratory (1998) (22)
- Human methadone detoxification: Opioid self-administration-behavior, cigarette smoking, and withdrawal signs and symptoms as a function of progressive dose reductions (1981) (21)
- An intensive assessment of alcohol use and emergency department utilization in homeless alcohol-dependent adults. (2017) (21)
- The effects of a cooperation contingency on behavior in a continuous three-person environment. (1976) (21)
- Employment-based reinforcement of adherence to oral naltrexone in unemployed injection drug users: 12-month outcomes. (2015) (20)
- Condom use rates for specific sexual behaviors among opioid abusers entering treatment. (1994) (20)
- Preliminary evidence of different and clinically meaningful opioid withdrawal phenotypes (2018) (20)
- Moderate drinking as an alternative to alcohol abuse: a non-aversive procedure. (1976) (20)
- Gradual dose taper following chronic buprenorphine. (2001) (20)
- The brief abstinence test: effects of continued incentive availability on cocaine abstinence. (2002) (20)
- Comparative Safety and Side Effect Profiles of Buprenorphine and Methadone in the Outpatient Treatment of Opioid Dependence (2005) (19)
- Short‐term effects of oral methadone in methadone maintenance subjects (1982) (19)
- Double-blind evaluation of reinforcing and anorectic actions of weight control medications. Interaction of pharmacological and behavioral treatments. (1980) (19)
- The role of behavioral contingency management in drug abuse treatment. (1984) (19)
- Self‐administration of clonidine, oxazepam, and hydromorphone by patients undergoing methadone detoxification (1985) (19)
- Narcotics addiction treatment: behavioral methods concurrent with methadone maintenance. (1980) (19)
- Pharmacokinetics and Pharmacodynamics of Methadone Enantiomers After Coadministration with Fosamprenavir‐Ritonavir in Opioid‐Dependent Subjects (2008) (19)
- Techniques used by smokers during contingency motivated smoking reduction. (1982) (19)
- Progress and needs in the experimental analysis of drug and alcohol dependence. (1982) (19)
- Outcome after methadone treatment: influence of prior treatment factors and current treatment status. (1994) (19)
- Abnormal CSF amyloid-β42 and tau levels in hip fracture patients without dementia (2018) (19)
- Food and Drug Administration approval of sustained-release buprenorphine for treatment of opioid dependence: realizing its potential. (2017) (19)
- Time course of naloxone-precipitated withdrawal after acute methadone exposure in humans. (1991) (18)
- Comparison of social time-out and activity time-out procedures in supressing ethanol self-administration in alcoholics. (1977) (18)
- Experimental human drug self-administration: methodology and application to the study of sedative abuse. (1975) (18)
- Opioid antagonist effects of dezocine in opioid‐dependent humans (1996) (18)
- Pupillary response to methadone challenge in heroin users (1985) (17)
- Measurement of self-reported HIV risk behaviors in injection drug users: comparison of standard versus timeline follow-back administration procedures. (2010) (17)
- Behavioral effects of morphine and methadone in rhesus monkeys (1971) (17)
- Safety and efficacy of L-tryptophan and behavioral incentives for treatment of cocaine dependence: a randomized clinical trial. (2004) (17)
- Useful predictors of outcome in methadone-treated patients : Results from a controlled clinical trial with three doses of methadone (1998) (16)
- Naloxone formulation for overdose reversal preference among patients receiving opioids for pain management. (2018) (16)
- Predicting the dependence liability of stimulant drugs. (1981) (15)
- Effects of incentives for naltrexone adherence on opiate abstinence in heroin‐dependent adults (2017) (15)
- HIV risk behaviors during pharmacologic treatment for opioid dependence: a comparison of levomethadyl acetate [corrected] buprenorphine, and methadone. (2006) (15)
- Social stimulus factors in drug effects in human subjects. (1981) (15)
- A behavioural-pharmacological treatment of dually addicted patients. (1972) (15)
- Intravenous hydromorphone: effects in opiate-free and methadone maintenance subjects. (1983) (15)
- Dose-response analysis of opioid cross-tolerance and withdrawal suppression during LAAM maintenance. (1998) (14)
- Treatment of Cocaine Abuse in Methadone Maintenance Patients (1998) (14)
- Experimental drug self-administration: generality across species and type of drug. (1978) (14)
- Contingency management of supplemental drug use during methadone maintenance treatment. (1984) (14)
- Supplementary methadone self administration among methadone maintenance clients. (1979) (13)
- Predictors of induction onto extended-release naltrexone among unemployed heroin-dependent adults. (2018) (12)
- Single‐day methadone dose alteration: Detectability and symptoms (1984) (12)
- Single- versus dual-drug target: effects in a brief abstinence incentive procedure. (2003) (12)
- Urinary Excretion Profile of 11-Nor-9-Carboxy-Δ9-Tetrahydrocannabinol (THCCOOH) Following Smoked and Vaporized Cannabis Administration in Infrequent Cannabis Users. (2019) (12)
- Pharmacokinetic Characterization of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Following Acute Oral Cannabis Ingestion in Healthy Adults. (2018) (12)
- Pharmacokinetics of Cannabis Brownies: A Controlled Examination of Δ9-Tetrahydrocannabinol and Metabolites in Blood and Oral Fluid of Healthy Adult Males and Females. (2020) (12)
- Comparison of cognitive performance in methadone maintenance patients with and without current cocaine dependence. (2012) (12)
- Managing acutely III substance-abusing patients in an integrated day hospital outpatient program (2006) (12)
- Analgesic Effects of Hydromorphone versus Buprenorphine in Buprenorphine-maintained Individuals (2019) (12)
- A comparison of voucher-delivery schedules for the initiation of cocaine abstinence. (2005) (11)
- Smoking cessation and relapse among cardiac patients. (1986) (11)
- Behavioral Approaches to Drug Abuse (1983) (11)
- Effects of cocaine alone and in combination with bromocriptine in human cocaine abusers. (1992) (11)
- The effects of extended-release injectable naltrexone and incentives for opiate abstinence in heroin-dependent adults in a model therapeutic workplace: A randomized trial. (2019) (11)
- Comparison of three outpatient methadone detoxification procedures. (1982) (11)
- Drug discrimination: methods for drug characterization and classification. (1989) (11)
- Effects of relaxation instructions on the electromyographic responses of abstinent alcoholics to drinking-related stimuli. (1977) (10)
- Buprenorphine Implants for Treatment of Opioid Dependence (2010) (10)
- Effects of Item Correction on Michigan Alcoholism Screening Test Scores in College Men With and Without a Family History of Alcoholism (1991) (10)
- Erratum: Evaluation of an injection depot formulation of buprenorphine: Placebo comparison (Addiction (2004) 99 (1439-1449)) (2005) (10)
- Effects of methadone plus alcohol on cognitive performance in methadone-maintained volunteers (2015) (10)
- Risk-taking propensity as a predictor of induction onto naltrexone treatment for opioid dependence. (2012) (9)
- Behavioral Treatments During Outpatient Methadone Maintenance: A Controlled Evaluation. (1976) (9)
- Treatment outcome in methadone detoxification: relationship to initial levels of illicit opiate use. (1983) (9)
- First randomized controlled trial (RCT) of methadone (M), levomethadyl acetate (LAAM) and buprenorphine (BUP) in opioid dependence treatment (1999) (9)
- Intravenous and oral l-alpha-acetylmethadol: pharmacodynamics and pharmacokinetics in humans. (1998) (9)
- Factors associated with using opiates while under extended-release naltrexone blockade: A descriptive pilot study. (2018) (9)
- Assessment of buprenorphine in a drug discrimination procedure in humans. (1992) (8)
- Pharmacokinetic Profile of Δ9-tetrahydrocannabinol, Cannabidiol and Metabolites in Blood following Vaporization and Oral Ingestion of Cannabidiol Products. (2022) (8)
- Contingent reinforcement of benzodiazepine-free urines from methadone maintenance patients. (1982) (8)
- The Effects of Cocaine in Buprenorphine‐Maintained Outpatient Volunteers: Results From Clinical Experience and Laboratory Challenges (1994) (8)
- The Effect of Repeated Intramuscular Alfentanil Injections on Experimental Pain and Abuse Liability Indices in Healthy Males (2014) (8)
- Increases in body mass index and cardiovascular risk factors during methadone maintenance treatment. (2019) (7)
- Regular article HIV risk behaviors during pharmacologic treatment for opioid dependence: A comparison of levomethadyl acetate, buprenorphine, and methadone (2006) (7)
- Behavior therapy in drug abuse treatment: review and evaluation. (1985) (7)
- Characterizing the subjective, observer-rated, and physiological effects of hydromorphone relative to heroin in a human laboratory study (2018) (7)
- Contingent methadone dose increases as a method for reducing illicit opiate use in detoxification patients. (1984) (7)
- Contingent methadone take-home privileges: effects on compliance with fee payment schedules. (1984) (7)
- Outpatient methadone detoxification: effects of diazepam and doxepin as adjunct medications. (1984) (7)
- Chronic opiate use during methadone detoxification: effects of a dose increase treatment. (1984) (7)
- Self-regulated opioid detoxification by humans: effects of methadone pretreatment. (1982) (7)
- Evaluation of the abuse potential of the novel analgesic flupirtine maleate. (1991) (7)
- Erratum: Effects of buprenorphine and methadone in methadone-maintained subjects (Psychopharmacology (1994) 119 (268-276)) (1995) (7)
- A clinical trial of buprenorphine: I. Comparison with methadone in the detoxification of heroin addicts. II. Examination of its opioid blocking properties. (1987) (7)
- The triply diagnosed: patients with major mental illness, cognitive impairment, and substance abuse. (1993) (6)
- Individual differences in human opioid abuse potential as observed in a human laboratory study. (2019) (6)
- Urinary Pharmacokinetic Profile of Cannabidiol (CBD), Δ9-Tetrahydrocannabinol (THC), and their Metabolites Following Oral and Vaporized CBD and Vaporized CBD-Dominant Cannabis Administration. (2021) (6)
- Assessment of effects of ethanol self-administration on social interactions in alcoholics (2004) (6)
- Comparison of the acute effects of buprenorphine and methadone in non- dependent humans (1993) (6)
- Abuse liability assessment of buprenorphine-naloxone combinations. (1987) (6)
- The index of choice: indications of methadone patients' selection of naltrexone treatment. (1984) (5)
- Toward application of the Therapeutic Workplace: Reply to Higgins (2001), Marlatt (2001), McLellan (2001), and Petry (2001). (2001) (5)
- Combination of naloxone with buprenorphine in humans. (1989) (5)
- Behavioral interventions in the methadone clinic: Contingent methadone take-home incentives (1993) (5)
- Prescription opioids: New perspectives and research on their role in chronic pain management and addiction. (2017) (5)
- Topiramate impairs cognitive function in methadone-maintained individuals with concurrent cocaine dependence. (2015) (4)
- Methadone detoxification: effects of methadone dose versus time in treatment. (1984) (4)
- Progress report from the Division of Behavioral Biology, the Johns Hopkins University School of Medicine. (1986) (4)
- Differences at Treatment Entry Between Opioid-Dependent and Cocaine-Dependent Males and Females (2004) (4)
- The relationship between pupil diameter and other measures of opioid withdrawal during naloxone precipitated withdrawal. (2019) (4)
- The Effects of Cocaine in Buprenorphine-Maintained Outpatient Volunteers (1994) (4)
- Butorphanol-precipitated withdrawal in opioid-dependent human volunteers. (1988) (4)
- Effects of item correction on Michigan Alcoholism Screening Test scores in college men with and without a family history of alcoholism. (1991) (4)
- Abuse liability and behavioral toxicity assessment: progress report from the behavioral biology laboratories of the Johns Hopkins University School of Medicine. (1984) (4)
- Fixed-ratio reinforcement of spaced responding. (1971) (3)
- Human preference comparison of pentobarbital, diazepam, and placebo. (1981) (3)
- Opioid abusers' ability to differentiate an opioid from placebo in laboratory challenge testing. (2013) (3)
- Three-way drug discrimination in post-addict volunteers: hydromorphone, pentazocine, and saline. (1986) (3)
- Buprenorphine effects in methadone-maintained subjects (1993) (3)
- Intravenous drug abusers with antisocial personality disorder: high rate of HIV-1 infection. (1990) (2)
- Methadone maintenance: high rate of other substance use disorders and relationship to psychiatric comorbidity. (1989) (2)
- Behavioral evaluation of drugs: A comparison of the behavioral effects of adinazolam and lorazepam (1993) (2)
- Therapeutic self-medication as a context for drug abuse research. (1978) (2)
- Enhanced cocaine effects during methadone maintenance (1993) (2)
- Providing medical care to methadone clinic patients: A controlled study of referral versus on-site care (1993) (2)
- WITHIN-SUBJECT EFFECTS OF PAY AMOUNT (2005) (2)
- Acute physical dependence in man: repeated naloxone-precipitated withdrawal after a single dose of methadone. (1989) (2)
- Methadone maintenance patients lack analgesic response to a cumulative intravenous dose of 32 mg of hydromorphone. (2021) (2)
- Biological vulnerability: treatment implications/applications. (1988) (2)
- Experimentally-induced spontaneous opiate withdrawal: relationship to cigarette craving and expired air carbon monoxide. (2007) (2)
- Physiological and subjective effects of hydromorphone in postaddict volunteers. (1982) (2)
- Human self-administration of sedative and stimulant drugs (1981) (2)
- President's comments: Behavioral science is fundamental to drug abuse research and treatment (1995) (2)
- Altered dose incentive procedures: effects on polydrug use among methadone maintenance patients. (1987) (1)
- Self-administration of clonidine and oxazepam by methadone detoxification patients. (1984) (1)
- Drug abuse research in outpatient clinics. (1978) (1)
- oncurrent validation of the Clinical Opiate Withdrawal Scale ( COWS ) and ingle-item indices against the Clinical Institute Narcotic Assessment ( CINA ) pioid withdrawal instrument (2009) (1)
- The effects of buprenorphine in methadone-dependent volunteers. (1990) (1)
- Discriminative stimulus effects of butorphanol, nalbuphine, naloxone and hydromorphone in opioid-dependent human volunteers (1988) (1)
- The influence of pregnancy upon trough plasma levels of methadone and its' opioid effects (1993) (1)
- Topiramate effect on weight gain during methadone maintenance (2015) (1)
- Extended-release injectable naltrexone (XR-NTX): a response to clinical issues raised by Brewer & Streel. (2018) (1)
- Development of clinical procedures for abuse liability assessment: progress report from the Behavioral Pharmacology Research Unit of the Johns Hopkins University School of Medicine and Baltimore City Hospitals. (1983) (1)
- Development of a human opioid drug discrimination procedure (1984) (1)
- Effects of a dose increase on chronic opiate use during methadone detoxification. (1984) (1)
- Reflections on the past 40 Years of Behavioral Pharmacology Research on Problems of Drug Abuse (2009) (1)
- Third-order fixed-ratio schedules of reinforcement (1968) (1)
- Response: Still room to improve an effective treatment (2005) (1)
- Clinical research methods for drug abuse medications development (1993) (0)
- An outpatient trial of methadone versus buprenorphine in the treatment of opioid dependence (1993) (0)
- Comparison of a behavioral and a pharmacological treatment for reduction of illicit opiate use. (1984) (0)
- Methadone-treated drug abusers: Reduced HIV infection and risk behavior (1990) (0)
- Rejected / , / 1( Design of a Programmed Environment for Th&* —* _ Experimental Analysis of Social Behavior * *2> ^, (2008) (0)
- (289) Conditioned Pain Modulation in Buprenorphine-Maintained Patients with Opioid Use Disorder (2019) (0)
- Relative Potency of levo - a -Acetylmethadol and Methadone in Humans under Acute Dosing Conditions 1 (1999) (0)
- Three-choice discrimination in methadone maintenance patients: hydromorphone, naloxone, and saline. (1984) (0)
- Heterogeneity of APD drug abusers on dimensional measures of personality and psychiatric distress (1993) (0)
- Acute physical dependence in naloxone-precipitated withdrawal methadone humans: repeated after a single dose of (1991) (0)
- Medication development for drug abuse treatment: Clinical research approaches (1991) (0)
- Employment-based reinforcement of naltrexone adherence in unemployed heroin users: Effects on opiate use (2017) (0)
- Clinical Evaluation of a Transdermal Buprenorphine Patch for Opioid Dependence: (709432007-001) (2007) (0)
- About this journal. (2012) (0)
- Degree of familial alcoholism: effects on substance use by college males. (1989) (0)
- OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR FIXED-RA TIO REINFORCEMENT OF SPACED RESPONDING ' GEORGE BIGELOW (2005) (0)
- Changes in drug abusers' HIV-1 risk behavior (1991) (0)
- Initial opiate use and treatment outcome in methadone detoxification patients. (1983) (0)
- Alcohol abuse: Behavioral functions of pharmacological adjuncts (1987) (0)
- Validity of drug abusers' reported HIV-1 risk behavior change (1993) (0)
- Characterizing the subjective, observer-rated, and physiological effects of hydromorphone relative to heroin in a human laboratory study (2017) (0)
- Correlates of impaired cognitive performance in cocaine- and opioid-dependent patients (2014) (0)
- Response to “Commercial Factors Override Science in Combination Addiction Drug Trial” (2011) (0)
- Contents of the American Journal of Psychiatry (1993) (0)
- Acute effects of secobarbital and ethanol as a function of family alcoholism history. (1990) (0)
- Opioid drug discriminations in humans (1990) (0)
- Reports from the Research Laboratories (1968) (0)
- Stress Reactivity: A Simple Classroom Demonstration (1994) (0)
- Staff's interactions with retarded patients during behavior modification. (1974) (0)
- Analgesia and abuse liability of high-dose intravenous opioids in patients on methadone or buprenorphine (2017) (0)
- Antagonist actions of the opioid analgesic nalbuphine in humans (1988) (0)
- A Pilot Study of Less‐Than‐Daily Dosing with Buprenorphine (B) (1996) (0)
- The role of human laboratory studies in drug abuse medications development (1993) (0)
- PREOPERATIVE CSF BIOMARKERS OF ALZHEIMER'S DISEASE IN A HIP FRACTURE POPULATION: AGE-DEPENDENT ASSOCIATION WITH UNDERLYING COGNITIVE FUNCTION (2017) (0)
- Methadone reinforcement of disulfiram taking in the treatment of alcoholic narcotic addicts (1973) (0)
- Randomized controlled evaluation of tramadol for opioid detoxification (2017) (0)
- An Experimental Approach Involving Conditioning Factors in Chronic Alcoholism (1971) (0)
- Research Group III. (1995) (0)
- Correlates of drug use severity and HIV risk behaviors in cocaine- and opiate-dependent patients (2014) (0)
- Dose effect and preference comparison of diazepam and oxazepam. (1984) (0)
- A prospective study of opioid induced hyperalgesia in healthy volunteers (2010) (0)
- Laam dose comparison: A clinical trial (1997) (0)
- Assessment of phenylpropanolamine (PP) abuse risk in weight control patients (1984) (0)
- Topiramate impairs cognitive function in cocaine-dependent individuals maintained on methadone (2014) (0)
- Factors influencing assessment of opioid miosis in humans. (1990) (0)
- Progress report from the Division of Behavioral Biology, the Johns Hopkins University School of Medicine. (1984) (0)
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