Gordon Ed Guroff

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Gordon Ed Guroff

Chemistry

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Chemistry

Gordon Ed Guroff's Degrees

PhD Chemistry University of California, Berkeley

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Gordon Ed Guroff's Published Works

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Published Works

Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. (1967) (443)
A NEUTRAL, CALCIUM-ACTIVATED PROTEINASE FROM THE SOLUBLE FRACTION OF RAT BRAIN. (1964) (420)
Regulation of the differentiation of PC12 pheochromocytoma cells. (1989) (293)
The effect of fibroblast growth factor on PC12 cells (1985) (250)
Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor (1981) (224)
Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B (2000) (201)
Cell cycle‐specific action of nerve growth factor in PC12 cells: differentiation without proliferation. (1989) (176)
Studies on aromatic amino acid uptake by rat brain in vivo. Uptake of phenylalanine and of tryptophan; inhibition and stereoselectivity in the uptake of tyrosine by brain and muscle. (1962) (171)
Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells. (1986) (166)
PURIFICATION OF NERVE GROWTH FACTOR ANTIBODIES BY AFFINITY CHROMATOGRAPHY (1976) (123)
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cells. (1991) (121)
Growth and Maturation Factors (1984) (117)
Calcium‐Dependent Nerve Growth Factor‐Stimulated Hydrolysis of Phosphoinositides in PC12 Cells (1987) (115)
Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor. (1980) (111)
The phosphorylation and DNA binding of the DNA-binding domain of the orphan nuclear receptor NGFI-B. (1993) (110)
PC12 Cells as a Model of Neuronal Differentiation (1985) (110)
The uptake of tyrosine by rat brain in vitro. (1961) (97)
Differential Regulation of the Transcriptional Activity of the Orphan Nuclear Receptor NGFI-B by Membrane Depolarization and Nerve Growth Factor* (1997) (88)
The neurite-promoting effect of fibroblast growth factor on PC12 cells. (1983) (87)
The Action of Adenosine Analogs on PC12 Cells (1981) (83)
The significance of retrograde axonal transport for the accumulation of systemically administered nerve growth factor (NGF) in the rat superior cervical ganglion (1976) (82)
Nerve growth factor-induced reduction in epidermal growth factor responsiveness and epidermal growth factor receptors in PC12 cells: an aspect of cell differentiation. (1979) (77)
The production of meta-chlorotyrosine from para-chlorophenylalanine by phenylalanine hydroxylase (1966) (69)
Nerve growth factor increases activity of ornithine decarboxylase in rat brain. (1978) (62)
Purification and mechanism of activation of a nerve growth factor-sensitive S6 kinase from PC12 cells. (1987) (62)
A simple radioisotope assay for phenylalanine hydroxylase. (1967) (61)
Citrate and action of vitamin D on calcium and phosphorus metabolism. (1963) (61)
K‐252a inhibits the increase in c‐fos transcription and the increase in intracellular calcium produced by nerve growth factor in PC12 cells (1989) (60)
The phosphorylation and activation of B-raf in PC12 cells stimulated by nerve growth factor. (1991) (60)
Nerve growth factor-induced decrease in the cell-free phosphorylation of a soluble protein in PC12 cells. (1983) (59)
Nerve growth factor increases activity of ornithine decarboxylase in superior cervical ganglia of young rats. (1977) (57)
A simple radioisotope assay for phenylalanine hydroxylase cofactor. (1967) (56)
Nerve growth factor, a differentiating agent, and epidermal growth factor, a mitogen, increase the activities of different S6 kinases in PC12 cells. (1988) (53)
Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. (1968) (53)
The effect of nerve growth factor on cycle AMP levels in superior cerival ganglia of the rat. (1975) (52)
HYPOXANTHINE‐GUANINE‐PHOSPHORIBOSYL‐TRANSFERASE FROM RAT BRAIN (PURIFICATION, KINETIC PROPERTIES, DEVELOPMENT AND DISTRIBUTION) (1972) (51)
Phenylalanine hydroxylation by Pseudomonas species (ATCC 11299a). Nature of the cofactor. (1969) (51)
Long-term, heterologous down-regulation of the epidermal growth factor receptor in PC12 cells by nerve growth factor (1987) (51)
Nerve growth factor-induced decrease in the calpain activity of PC12 cells. (1989) (50)
STUDIES ON THE ORIGIN OF PYRIMIDINES FOR BIOSYNTHESIS OF NEURAL RNA IN THE RAT (1971) (49)
Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine. (1966) (48)
BIOSYNTHESIS OF RIBONUCLEIC ACID IN RAT BRAIN SLICES (1968) (46)
The production of meta-tritiotyrosine from p-tritiophenylalanine by phenylalanine hydroxylase. (1966) (45)
K 252 a a specific inhibitor of the action of nerve growth factor on pc12 cells (1987) (45)
The Effect of the B Subunit of Cholera Toxin on the Action of Nerve Growth Factor on PC12 Cells (1993) (44)
Nerve growth factor: mechanism of action. (1980) (43)
Differentiation of PC12 cells with v‐src: Comparison with nerve growth factor (1989) (43)
The Induction of Ornithine Decarboxylase by Nerve Growth Factor and Epidermal Growth Factor in PC 12 Cells (1981) (43)
Irreversible in vivo inhibition of rat liver phenylalanine hydroxylase by p-chlorophenylalanine. (1969) (41)
The Wilms' Tumor Gene Product WT1 Mediates the Down-regulation of the Rat Epidermal Growth Factor Receptor by Nerve Growth Factor in PC12 Cells* (2001) (41)
Nerve growth factor‐induced increase in calcium uptake by PC12 cells (1991) (39)
The migration of deuterium during aryl hydroxylation. II. Effect of induction of microsomal hydroxylases with phenobarbital or polycyclic aromatic hydrocarbons. (1969) (38)
ENZYMES OF NUCLEIC ACID METABOLISM IN THE BRAINS OF YOUNG AND ADULT RATS (1971) (37)
Enduring behavioral changes in rats with experimental phenylketonuria. (1972) (36)
Hydroxylation-induced migrations of tritium in several substrates of liver aryl hydroxylases. (1967) (35)
Pineal gland cells in culture. Morphology, Biochemistry, Differentiation, and co-culture with sympathetic neurons. (1977) (34)
Biosynthesis of pteridines and of phenylalanine hydroxylase cofactor in cell-free extracts of Pseudomonas species (ATCC 11299a). (1966) (34)
Delayed and Sustained Activation of p42/p44 Mitogen‐Activated Protein Kinase Induced by Proteasome Inhibitors Through p21ras in PC12 Cells (2000) (34)
Increased Levels of Neuron‐Specific Enolase in PC 12 Pheochromocytoma Cells as a Result of Nerve Growth Factor Treatment (1982) (33)
Phenylalanine hydroxylase from Pseudomonas species (ATCC 11299a). Purification of the enzyme and activation by various metal ions. (1967) (32)
Partial purification and characterization of a nerve growth factor-sensitive kinase and its substrate from PC12 cells (1985) (32)
Quantitative studies on the hydroxylation-induced migration of deuterium and tritium during phenylalanine hydroxylation. (1967) (32)
Expression of human p140trk receptors in p140trk‐deficient, PC12/endothelial cells results in nerve growth factor‐induced signal transduction and DNA synthesis (1997) (32)
PHENYLALANINE HYDROXYLATION BY PSEUDOMONAS SPECIES (ATCC 11299A). (1965) (32)
Effect of various vitamin deficiencies on citric acid metabolism in the rat. (1961) (32)
Production of m-methyltyrosine and p-hydroxymethylphenylalanine from p-methylphenylalanine by phenylalanine hydroxylase. (1968) (32)
Transcriptional Down-regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor Treatment of PC12 Cells* (1998) (32)
A study of cellular transport with the fluorescent amino acid, aminonaphthylalanine. (1966) (32)
Sequence of a rat TIS11 cDNA, an immediate early gene induced by growth factors and phorbol esters. (1992) (31)
POLYADENYLIC ACID‐CONTAINING RNA FROM RAT BRAIN (1975) (30)
Oncogenes, Genes, And Growth Factors (1987) (30)
Decreased levels of nerve growth factor receptor on dexamethasone‐treated PC12 cells (1988) (29)
Nerve growth factor and K‐252a increase catecholamine release from PC12 cells (1990) (28)
Intramolecular migration of deuterium and tritium during enzymic hydroxylation of p-deuteroacetanilide and p-tritioacetanilide. (1967) (28)
Voltage-sensitive calcium currents are acutely increased by nerve growth factor in PC12 cells. (1999) (27)
The biosynthesis of phosphorylated tyrosine hydroxylase by organ cultures of rat adrenal medulla and superior cervical ganglia: a correction. (1977) (27)
Effects of 12‐0‐tetradecanoylphorbol‐13‐acetate (TPA) on rat pheochromocytoma (PC12) cells: Interactions with epidermal growth factor and nerve growth factor (1982) (27)
Isotope studies on the mechanism of action of adrenal tyrosine hydroxylase. (1968) (25)
INDUCED, SOLUBLE PHENYLALANINE HYDROXYLASE FROM PSEUDOMONAS SP. GROWN ON PHENYLALANINE OR TYROSINE. (1963) (24)
Nerve growth factor‐stimulated calcium uptake into PC12 cells: Uniqueness of the channel and evidence for phosphorylation (1992) (24)
The binding of RNA to various celluloses. (1973) (23)
STIMULATION OF AROMATIC AMINO ACID TRANSPORT BY P-FLUOROPHENYLALANINE IN THE SARCOMA 37 CELL. (1964) (23)
The uptake of tyrosine by isolated rat diaphragm. (1960) (23)
The tryptophan hydroxylase of Chromobacterium violaceum. (1974) (22)
THE UPTAKE OF PURINES BY RAT BRAIN IN VIVO AND IN VITRO (1973) (22)
The Uptake of Aromatic Amino Acids by the Brain of Mature and Newborn Rats (1964) (21)
Partial purification and properties of guanosine triphosphate cyclohydrolase, the first enzyme in pteridine biosynthesis, from Comamonas sp. (ATCC 11299a). (1971) (21)
Selective de novo synthesis of tyrosine hydroxylase in organ cultures of rat superior cervical ganglia after in vivo administration of nerve growth factor. (1977) (20)
Multiple acute effects on the membrane potential of PC12 cells produced by nerve growth factor (NGF) (2005) (20)
Inhibition of the phosphorylation of a 1000,000-dalton soluble protein in whole cells and cell-free extracts of PC12 pheochromocytoma cells following treatment with nerve growth factor. (1982) (20)
The enduring behavioral changes in rats with experimental phenylketonuria. (1974) (20)
The permissive effect of cortical steroids on the induction of brain ornithine decarboxylase by nerve growth factor. (1978) (20)
Intracellular calcium levels regulate the actions of nerve growth factor on calcium uptake in PC12 cells (1992) (19)
POLYADENYLIC ACID‐CONTAINING RNA FROM RAT BRAIN SYNAPTOSOMES (1975) (19)
A Nerve Growth Factor‐Sensitive S6 Kinase in Cell‐Free Extracts from PC 12 Cells (1986) (19)
Epidermal growth factor stimulates the phosphorylation of a specific nuclear protein in chick embryo epidermis. (1978) (18)
Rapid assay for purine phosphoribosyltransferases. (1972) (18)
BRAIN NUCLEIC ACIDS (1980) (18)
The Receptor‐Mediated Activation of Tyrosine Hydroxylation in the Superior Cervical Ganglion of the Rat (1981) (18)
Identification of nerve growth factor receptors in primary cultures of chick neural crest cells. (1983) (17)
INCREASED CEREBRAL EXCITABILITY CAUSED BY p‐CHLOROPHENYLALANINE IN YOUNG RATS (1971) (17)
Identification of Nsp100 as elongation factor 2 (EF‐2) (1989) (16)
Induction of ornithine decarboxylase by renin-free nerve growth factor. (1980) (16)
Nerve growth factor-induced increase in the cell-free phosphorylation of a nuclear protein in PC12 cells. (1985) (16)
Intraventricular administration of nerve growth factor induces ornithine decarboxylase in peripheral tissues of the rat. (1978) (16)
The synthesis of RNA which binds to oligo(dT)-cellulose by brain in vivo and in vitro. (1972) (16)
Ontogeny of the nerve growth factor receptor in primary cultures of neural crest cells. (1986) (16)
ENZYMATIC FORMATION OF PHENYLPYRUVIC ACID IN PSEUDOMONAS SP. (ATCC 11299A) AND ITS REGULATION. (1965) (16)
Effects of amino acids, analogs, and certain other agents in relation to tyrosine transport in sarcoma 37 ascites cells. (1962) (16)
Intramolecular Migrations during Hydroxylation of Aromatic Compounds: The NIH Shift (1968) (15)
Identification of D-erythro-dihydroneopterin triphosphate, the first product of pteridine biosynthesis in Comamonas sp. (ATCC 11299a). (1974) (15)
Down‐Regulation of c‐neu Receptors by Nerve Growth Factor in PC12 Cells (1995) (15)
Control of adenylate cyclase from secretory vesicle membranes by beta-adrenergic agents and nerve growth factor. (1976) (15)
Phenylalanine hydroxylase from Pseudomonas sp. (ATCC 11299a). Purification, molecular weight, and influence of tyrosine metabolites on activation and hydroxylation. (1975) (14)
Purification and properties of guanosine triphosphate cyclohydrolase and a stimulating protein from Comamonas sp. (ATCC 11299a). (1974) (14)
Phenylalanine uptake and phenylalanine-binding material in Comamonas sp. (ATCC 11299a). (1970) (14)
NERVE GROWTH FACTOR AND THE ACTIVITY OF TYROSINE HYDROXYLASE IN ORGAN CULTURES OF RAT SUPERIOR CERVICAL GANGLIA (1977) (14)
Metabolism of Aromatic Amino Acids (1970) (14)
Enzymic and nonenzymic hydroxylation and chlorination of p-deuteroanisole. (1968) (13)
URIDINE PHOSPHORYLASE FROM RAT BRAIN: CHARACTERISTICS AND DEVELOPMENTAL COURSE (1969) (13)
Isolation and characterization of dihydropteridine reductase from Pseudomonas species (1976) (13)
THE DE NOVO SYNTHESIS OF TYROSINE HYDROXYLASE IN RAT SUPERIOR CERVICAL GANGLIA IN VITRO: THE EFFECT OF NERVE GROWTH FACTOR (1977) (13)
Effects of nerve growth factor and nerve growth factor antiserum on tyrosine hydroxylase and dihydropterine reductase activities in rat superior cervical ganglia in vim (1977) (12)
Nerve Growth Factor as a Neurotrophic Agent (1993) (12)
Nerve Growth Factor-induced Alteration in the Response of PC 12 Pheochromocytoma Cells to Epidermal Growth Factor (2003) (12)
Increased phosphorylation of a specific nuclear protein in rat superior cervical ganglia in response to nerve growth factor. (1978) (12)
Induction of tyrosine hydroxlase synthesis in rat superior cervical ganglia in vitro by nerve growth factor and dexamethasone. (1977) (11)
Mode of action of p-chlorophenylalanine on Pseudomonas species (11299a). (1969) (11)
BRAIN AMINO ACIDS (1980) (10)
Okadaic acid stimulates the activity of the nerve growth factor-sensitive S6 kinase of PC12 cells. (1991) (9)
The role of phosphorylation in the action of nerve growth factor. (1989) (9)
Nerve Growth Factor and Gangliosides Stimulate the Release of Glycoproteins from PC 12 Pheochromocytoma Cells (1986) (9)
The phenylalanine-binding protein of Comamonas sp. (ATCC 11299a). (1971) (9)
Down-regulation of cyclin F levels during nerve growth factor-induced differentiation of PC12 cells. (1996) (9)
The failure of insulin to effect the transport of tyrosine in the isolated rat diaphragm. (1961) (8)
Some characteristics of the p-chlorophenylalanine-induced cataract. (1973) (8)
A nerve growth factor-sensitive S6 kinase in cell-free extracts from PC12 cells. (1986) (8)
BIOCHEMICAL AND BEHAVIORAL CHANGES IN RATS WITH EXPERIMENTAL PHENYLKETONURIA (1973) (7)
Simultaneous visualization of the binding of nerve growth factor and epidermal growth factor to single rat pheochromocytoma (PC12) cells through indirect immunohistofluorescence. (1982) (7)
Nerve Growth Factor and Other Factors Acting on the Nervous System (1983) (7)
[Hypoxanthine-guanine-phosphoribosyltransferase from rat brain]. (1972) (7)
Urinary metabolites of phenylalanine in the preweanling rat treated with p-chlorophenylalanine and phenylalanine. (1975) (7)
Fluorescence of the fluorinated phenylalanines. (1962) (6)
Nerve Growth Factor-induced Decrease in the Cell-free Phosphorylation of a Soluble Protein in PC 12 Cells * (6)
The Effects of Nerve Growth Factor on Poly amine Metabolism in PC12 Cells (1983) (6)
Insulin‐Like Growth Factor I Receptor Expression and Function in Nerve Growth Factor‐Differentiated PC12 Cells (1996) (6)
Differentiation of PC12 cells with K‐ras: Comparison with nerve growth factor (1991) (6)
Involvement of protein kinase C in nerve growth factor‐ and K‐252a‐stimulated calcium uptake into PC12 cells (1997) (6)
ULTRASTRUCTURAL CHANGES IN RAT OPTIC NERVE ASSOCIATED WITH HYPERPHENYLALANINEMIA INDUCED BY PARACHLOROPHENYLALANINE AND PHENYLALANINE (1975) (5)
Both P140 TRK and P75NGFR nerve growth factor receptors mediate nerve growth factor-stimulated calcium uptake (1997) (5)
Preparation of affinity-purified, biotinylated tetanus toxin, and characterization and localization of cell surface binding sites on nerve growth factor-treated PC12 cells (1990) (5)
Evidence for an indirect effect of nerve growth factor (NGF) on the ADP-ribosylation of a 22 kDa rho-like protein in PC12 cells. (1993) (5)
CHARACTERISTICS OF THE PURIFIED NERVE GROWTH FACTOR ANTIBODY (1978) (4)
Separation of the enantiomers of the aminonaphthylalanines by paper chromatography (1966) (4)
The long‐term down‐regulation of dihydropyridine receptors by bay K 8644 in PC12 cells (1994) (4)
Chapter 8 – GROWTH FACTORS FOR THE NERVOUS SYSTEM (1988) (4)
Nerve Growth Factor‐Stimulated Nuclear S6 Kinase in PC12 Cells (1996) (4)
The effect of bovine serum albumin on the measurement of the activity of highly purified Comamonas phenylalanine hydroxylase. (1970) (4)
Preparation of a cell-free translation system from PC12 cells (1996) (3)
Characteristics of the K‐252a‐induced increase in calcium uptake in PC12 cells (1995) (3)
The receptor-mediated, short-term activation of tyrosine hydroxylase in organ cultures of rat superior cervical ganglia. (1979) (3)
Glycoconjugate Metabolism, Accretion and Release During Neurite Outgrowth in Normal and Transformed Cells of Neuronal Origin (1987) (3)
The nerve growth factor family (1996) (3)
BIOSYNTHESIS OF PHENYLALANINE HYDROXYLASE COFACTOR BY CELL-FREE EXTRACTS OF PSEUDOMONAS SP. (ATCC 11299A). (1964) (3)
Decreased micrococcal nuclease sensitivity of nuclei from nerve growth factor-treated PC12 cells. (1983) (3)
[74] Phenylalanine hydroxylase (Pseudomonas)☆ (1970) (3)
Norepinephrine and nerve growth factor: similar proteins phosphorylated in the nuclei of target cells. (1982) (2)
Growth regulation by nerve growth factor (1979) (2)
The biosynthesis of phosphorylated tyrosine hydroxylase by organ cultures of rat medulla and superior cervical ganglia. (1977) (2)
Effect of dexamethasone on the nerve growth factor‐induced increase in the NILE glycoprotein in PC12 cells (1992) (1)
Methods in enzymology (1986) (1)
Gordon Guroff and Sidney Udenfriend The Uptake of Tyrosine by Isolated Rat Diaphragm (2003) (1)
Methods in neurosciences: Vol. 5, neuropeptide technology: Gene expression and neuropeptide receptors; Vol. 6, neuropeptide technology: Synthesis, assay, purification, and processing. Edited by P. Michael Conn, Academic Press, New York, 1991. Vol. 5, 570 pp., $89.00, hardcover; $49.95, loose-leaf. V (1992) (1)
Effects of nerve growth factor and nerve growth factor antiserum on tyrosine hydroxylase and dihydropterine reductase activities in rat superior cervical ganglia in vivo. (1977) (1)
[171] Radioisotope assay for reduced pteridines: the phenylalanine hydroxylase cofactor (1971) (1)
Intramolecular migrations of aryl substituents during enzymatic hydroxylation. (1968) (1)
The Mechanism of Action of Nerve Growth Factor (1990) (0)
Phenylketonuria - Clinical and Biochemical Relationship (1978) (0)
[Nerve growth factor and ornithine decarboxylase (author's transl)]. (1981) (0)
Methods in enzymology: Vol. 198, Peptide Growth Factors, Part C. Edited by D. Barnes, J. P. Mather and G. H. Sato. Academic Press, San Diego, CA, 1991. 640 pp. $79.00 (1991) (0)
Long-term down-regulation of EGF-dependent tyrosine kinase activity in PC12 cells (1986) (0)
Separation of the enantiomers of the aminonaphthyl-alanines by paper chromatography. (1966) (0)
Influence on glial/neuronal cells by hormones and gangliosides: trophic factors and informational substances (1987) (0)
Down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells is P140 TRK -, RAS-, and SRC-dependent (1997) (0)
SIGNIFICANCE OF THE NIH SHIFT WITH RESPECT TO LIVER MICROSOME HYDROXYLATIONS (1969) (0)
Nerve growth factor and gangliosides stimulate the release of glycoproteins from PC12 pheochromocytoma cells. (1986) (0)
Control of adenylate cyclase from secretory vesicle membranes by f 3-adrenergic agents and nerve growth factor ( chromaffin granule / a-receptor / membrane purification ) (0)
Straurosporine induces neurite outgrowth in PC12 variant cell lines by trkA-, ras, and src- independent signal transduction pathways (1997) (0)
Expression of human P140TRK receptors in P140TRK- deficient PC12/endothelial (PpC12EN) cells results in nerve growth factor (NGF)-induced signal transduction and DNA synthesis (1997) (0)
Ultrastructural changes in rat optic nerve associated with hyperphenylalaninemia induced by para-chlorophenylalanine and phenylalanine. (1975) (0)
Methods in enzymology: Vols. 146 and 147, Peptide Growth Factors, Parts A and B. Edited by David Barnes and David A. Sirbasku, Academic Press, Orlando, FL, 1987. 452 and 487 pp., $59.00 each (1988) (0)
Nerve Growth Factor-induced Decrease in the Calpain Activity of P C 12 Cells (2001) (0)
Gordon Guroff , William King and Sidney Udenfriend in Vitro The Uptake of Tyrosine by Rat Brain (2003) (0)
Chemical control of neuronal growth--the nerve growth factor. (1978) (0)
Cloning and Characterization of the Promoter Region of the Rat Epidermal Growth Factor Receptor Gene and Its Transcriptional Regulation by Nerve Growth Factor in PC 12 Cells * (2000) (0)
Calpain levels during differentiation of PC12 cells (1992) (0)

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