Gerald J. Chader
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Medical Biology
Why Is Gerald J. Chader Influential?
(Suggest an Edit or Addition)Gerald J. Chader's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. (1993) (464)
- A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. (1988) (456)
- Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. (1994) (437)
- Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. (2010) (231)
- Retinoid requirements for recovery of sensitivity after visual-pigment bleaching in isolated photoreceptors. (1989) (226)
- Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis. (2009) (224)
- Retinoblastoma—origin from a primitive neuroectodermal cell? (1984) (223)
- Rod-cone dysplasia in Irish setters: a defect in cyclic GMP metabolism in visual cells. (1978) (211)
- Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. (2013) (206)
- Pathology of experimental autoimmune uveoretinitis in mice. (1990) (202)
- Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin. (1996) (199)
- PHARMACOLOGY OF THE EYE (1984) (181)
- Uveoretinitis and pinealitis induced by immunization with interphotoreceptor retinoid-binding protein. (1986) (175)
- Accumulation of glial fibrillary acidic protein in Müller radial glia during retinal degeneration. (1988) (166)
- Stem cell based therapies for age-related macular degeneration: The promises and the challenges (2015) (161)
- Cellular immune responses of patients with uveitis to retinal antigens and their fragments. (1990) (159)
- Induction of heme oxygenase 1 in the retina by intense visible light: suppression by the antioxidant dimethylthiourea. (1995) (152)
- Pigment Epithelium‐Derived Factor Is a Survival Factor for Cerebellar Granule Cells in Culture (1995) (152)
- Molecular characterization of human TRPM-2/clusterin, a gene associated with sperm maturation, apoptosis and neurodegeneration. (1994) (149)
- The presence of a soluble interphotoreceptor retinol‐binding protein (IRBP) in the retinal interphotoreceptor space (1983) (148)
- Isolation and characterization of monkey interphotoreceptor retinoid-binding protein, a unique extracellular matrix component of the retina. (1985) (144)
- Interphotoreceptor retinol-binding proteins: possible transport vehicles between compartments of the retina (1982) (142)
- Animal models in research on retinal degenerations: past progress and future hope (2002) (139)
- Endogenous fatty acids are covalently and noncovalently bound to interphotoreceptor retinoid-binding protein in the monkey retina. (1985) (123)
- Increased expression of heme oxygenase‐1 in human retinal pigment epithelial cells by transforming growth factor‐β (1994) (120)
- Pigment Epithelium‐Derived Factor Protects Cultured Cerebellar Granule Cells Against Glutamate‐Induced Neurotoxicity (1997) (117)
- Pigment epithelium‐derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death (1998) (116)
- Interphotoreceptor retinoid-binding protein. Gene characterization, protein repeat structure, and its evolution. (1989) (115)
- Retinal photoreceptor neurons and pinealocytes accumulate mRNA for interphotoreceptor retinoid‐binding protein (IRBP) (1986) (112)
- Interphotoreceptor retinoid-binding protein: role in delivery of retinol to the pigment epithelium. (1989) (108)
- Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP) (1989) (107)
- Chromosomal localization of the human heme oxygenase genes: heme oxygenase-1 (HMOX1) maps to chromosome 22q12 and heme oxygenase-2 (HMOX2) maps to chromosome 16p13.3. (1994) (105)
- INTERPHOTORECEPTOR RETINOID‐BINDING PROTEIN AND α‐TOCOPHEROL PRESERVE THE ISOMERIC AND OXIDATION STATE OF RETINOL (1992) (105)
- Retinoids and the Visual Process (1996) (103)
- FUNCTIONAL PROPERTIES OF INTERPHOTORECEPTOR RETINOID‐BINDING PROTEIN * (1991) (100)
- Interphotoreceptor retinoid-binding protein promotes rhodopsin regeneration in toad photoreceptors. (1990) (100)
- Structural analysis of the human hydroxyindole-O-methyltransferase gene. Presence of two distinct promoters. (1994) (98)
- Distribution of IGF-I and -II, IGF binding proteins (IGFBPs) and IGFBP mRNA in ocular fluids and tissues: potential sites of synthesis of IGFBPs in aqueous and vitreous. (1993) (98)
- Interphotoreceptor retinoid-binding protein (IRBP). Molecular biology and physiological role in the visual cycle of rhodopsin. (1993) (98)
- Interphotoreceptor retinoid-binding protein (IRBP): a model protein for molecular biological and clinically relevant studies. Friedenwald lecture. (1989) (97)
- Genetic control of susceptibility to experimental autoimmune uveoretinitis in the mouse model: Concomitant regulation by MHC and non-MHC genes (1991) (96)
- Overexpression of fetal human pigment epithelium-derived factor in Escherichia coli. A functionally active neurotrophic factor. (1993) (96)
- Identification of pigment epithelium-derived factor in the interphotoreceptor matrix of bovine eyes. (1995) (92)
- The metabolism of fatty acids in human Bietti crystalline dystrophy. (2001) (89)
- The mouse as a model of experimental autoimmune uveoretinitis (EAU). (1990) (88)
- The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. (2007) (85)
- Retinal degeneration in the dog. III. Abnormal cyclic nucleotide metabolism in rod-cone dysplasia. (1982) (83)
- Evidence for an Insulin‐Like Growth Factor Autocrine‐Paracrine System in the Retinal Photoreceptor‐Pigment Epithelial Cell Complex (1991) (83)
- Interphotoreceptor retinoid-binding protein in retinal rod cells and pineal gland. (1986) (82)
- Cyclic GMP: control of concentration by light in retinal photoreceptors. (1976) (82)
- A receptor for retinol in the developing retina and pigment epithelium. (1975) (78)
- Localization of the gene for pigment epithelium-derived factor (PEDF) to chromosome 17p13.1 and expression in cultured human retinoblastoma cells. (1994) (76)
- Differential binding to soluble nuclear receptors and effects on cell viability of retinol and retinoic acid in cultured retinoblastoma cells. (1977) (76)
- Recognition of peptides that are immunopathogenic but cryptic. Mechanisms that allow lymphocytes sensitized against cryptic peptides to initiate pathogenic autoimmune processes. (1991) (74)
- Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3','5-monophosphate (1982) (74)
- Experimental autoimmune uveoretinitis (EAU) induced by retinal interphotoreceptor retinoid-binding protein (IRBP): differences between EAU induced by IRBP and by S-antigen. (1987) (67)
- CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF THE BOVINE RETINA: ACTIVITY, SUBCELLULAR DISTRIBUTION AND KINETIC PARAMETERS (1974) (65)
- Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments. (1997) (65)
- Characterization of guanylate cyclase of rod outer segments of the bovine retina. (1978) (64)
- EFFECTS OF LIGHT ON CYCLIC GMP METABOLISM IN RETINAL PHOTORECEPTORS (1976) (64)
- Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina. (1986) (61)
- The pineal gland does not control rod outer segment shedding and phagocytosis in the rat retina and pigment epithelium. (1978) (61)
- Choroideremia: a clinical, electron microscopic, and biochemical report. (1984) (61)
- Cyclic nucleotide metabolism in inherited retinopathy in collies: a biochemical and histochemical study. (1982) (61)
- Interaction of Neuropeptides and Cultured Glial (Müller) Cells of the Chick Retina: Elevation of Intracellular Cyclic AMP by Vasoactive Intestinal Peptide and Glucagon (1984) (60)
- Steroid-protein interactions. 18. Isolation and observations on the polymeric nature of the corticosteroid-binding globulin of the rat. (1968) (59)
- Light activation of phosphodiesterase activity in retinal rod outer segments. (1974) (58)
- PEDF: Raising both hopes and questions in controlling angiogenesis (2001) (58)
- Experimental autoimmune uveoretinitis in mice. Induction by a single eliciting event and dependence on quantitative parameters of immunization. (1990) (55)
- Non-allelism of three genes (rcd1, rcd2 and erd) for early-onset hereditary retinal degeneration. (1989) (55)
- Endogenous phosphorylation of retinal photoreceptor outer segment proteins by calcium phospholipid-dependent protein kinase. (1984) (55)
- Chapter 6 Interphotoreceptor retinol-binding protein: A possible role in retinoid transport to the retina (1983) (54)
- Retinal insulin receptors: localization using a polyclonal anti-insulin receptor antibody (1988) (53)
- The early appearance of disc shedding in the rat retina. (1979) (52)
- Cloning and characterization of a chick embryo cDNA and gene for IGF-binding protein-2. (1995) (52)
- Butyrate enhances the synthesis of interphotoreceptor retinoid‐binding protein (IRBP) by Y‐79 human retinoblastoma cells (1985) (51)
- Steroid-protein interactions. XVI. Isolation and characterization of the corticosteroid-binding globulin of the rabbit. (1968) (51)
- IGF-I receptors in the bovine neural retina: structure, kinase activity and comparison with retinal insulin receptors. (1988) (50)
- Retinoblastoma. Immunohistochemistry and cell differentiation. (1987) (50)
- Protein tyrosine kinase and protein phosphotyrosine phosphatase in normal and psoriatic skin. (1984) (50)
- Insulin and IGF-I binding in developing chick neural retina and pigment epithelium: a characterization of binding and structural differences. (1991) (49)
- Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures. (1984) (49)
- Retinoblastoma: a primitive tumor with multipotential characteristics. (1986) (49)
- Immunochemical distribution of interphotoreceptor retinoid-binding protein in selected species. (1986) (48)
- Hormonal effects on the neural retina: corticoid uptake, specific binding and structural requirements for the induction of glutamine synthetase. (1972) (48)
- Neural retinal and pigment epithelial cells in culture: patterns of differentiation and effects of prostaglandins and cyclic-AMP on pigmentation. (1976) (48)
- Attachment culture of human retinoblastoma cells: long-term culture conditions and effects of dibutyryl cyclic AMP. (1984) (47)
- Glucocorticoid receptors. Characteristics, specificity, and ontogenesis in embryonic chick neural retina. (1974) (46)
- Local synthesis and developmental regulation of avian vitreal insulin-like growth factor-binding proteins: a model for independent regulation in extravascular and vascular compartments. (1992) (46)
- Differentiation of Y79 retinoblastoma cells with pigment epithelial-derived factor and interphotoreceptor matrix wash: effects on tumorigenicity. (1994) (46)
- A novel method for the isolation of tissue-specific genes (1992) (45)
- Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors (1974) (45)
- Matrigel promotes retinoblastoma cell growth in vitro and in vivo (1992) (44)
- A developmental study of interphotoreceptor retinoid-binding protein (IRBP) in single and double homozygous rd and rds mutant mouse retinae. (1988) (44)
- Preface: The aging eye: normal changes, age-related diseases, and sight-saving approaches. (2013) (43)
- Retinal pigment epithelium in culture demonstrates a distinct β-adrenergic receptor (1984) (43)
- Lymphocyte responses to retinal-specific antigens in uveitis patients and healthy subjects. (1988) (43)
- Identification, isolation, and characterization of a 32-kDa fatty acid-binding protein missing from lymphocytes in humans with Bietti crystalline dystrophy (BCD). (1998) (42)
- Studies on estradiol receptors of the rat uterus. Nuclear uptake in vitro. (1970) (42)
- Synthetic peptides derived from IRBP induce EAU and EAP in Lewis rats. (1988) (42)
- Dissociation between lymphocyte activation for proliferation and for the capacity to adoptively transfer uveoretinitis. (1987) (42)
- VITAMIN A RECEPTORS: RETINOL BINDING IN NEURAL RETINA AND PIGMENT EPITHELIUM (1977) (42)
- Increased TRPM-2/clusterin mRNA levels during the time of retinal degeneration in mouse models of retinitis pigmentosa. (1994) (42)
- Hormonal effects on the neural retina. I. Glutamine synthetase development in the retina and liver of the normal and triiodothyronine-treated rat. (1971) (39)
- Vitreal insulin-like growth factor binding proteins (IGFBPs) are increased in human and animal diabetics. (1994) (38)
- Retinal insulin receptors. 2. Characterization and insulin-induced tyrosine kinase activity in bovine retinal rod outer segments. (1987) (38)
- Scleral matrix metalloproteinases, serine proteinase activity and hydrational capacity are increased in myopia induced by retinal image degradation. (1996) (38)
- Retinoid processing in retinal pigment epithelium of toad (Bufo marinus). (1994) (37)
- Expression of multiple forms of clusterin during light-induced retinal degeneration (2001) (36)
- Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP. (1974) (36)
- Retinol receptors of the retina and pigment epithelium: further characterization and species variation. (1976) (36)
- Dominantly inherited retinitis pigmentosa. Ultrastructure and biochemical analysis. (1985) (36)
- Differential phosphorylation by GTP and ATP in isolated rod outer segments of the retina. (1976) (36)
- Retinoblastoma cells in tissue culture. (1988) (35)
- Synthesis of interphotoreceptor retinoid-binding protein (IRBP) by monkey retina in organ culture: effect of monensin. (1984) (35)
- Interphotoreceptor retinoid-binding protein Characteristics in bovine and monkey retina (1984) (35)
- Vitamin A receptors. Retinoic acid binding in ocular tissues. (1978) (34)
- Retinal insulin receptors. 1. Structural heterogeneity and functional characterization. (1987) (34)
- The gene for PEDF, a retinal growth factor is a prime candidate for retinitis pigmentosa and is tightly linked to the RP13 locus on chromosome 17p13.3. (1996) (34)
- Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis (2008) (34)
- Interphotoreceptor retinoid-binding protein (IRBP) (1993) (34)
- Rat T-cell lines specific to a nonimmunodominant determinant of a retinal protein (IRBP) produce uveoretinitis and pinealitis. (1989) (34)
- A soluble receptor for corticoids in the neural retina of the chick embryo. (1972) (34)
- Screening of a Large Cohort of Leber Congenital Amaurosis and Retinitis Pigmentosa Patients Identifies Novel LCA5 Mutations and New Genotype–Phenotype Correlations (2013) (34)
- Oxidative stress induces heme oxygenase-1 immunoreactivity in Müller cells of mouse retina in organ culture. (2001) (33)
- Structural and comparative analysis of the mouse gene for pigment epithelium-derived factor (PEDF). (1998) (33)
- Agonist Effects on the Intracellular Cyclic AMP Concentration of Retinal Pigment Epithelial Cells in Culture (1984) (32)
- Vitamin A receptors of the retina: differential binding in light and dark. (1979) (32)
- Neuron-specific enolase: a neuronal survival factor in the retinal extracellular matrix? (1995) (32)
- Phorbol ester- and light-induced endogenous phosphorylation of rat rod outer-segment proteins. (1987) (31)
- Changes in clusterin expression associated with light-induced retinal damage in rats. (1994) (30)
- Laminin-induced retinoblastoma cell differentiation: possible involvement of a 100-kDa cell-surface laminin-binding protein. (1992) (30)
- Clusterin protein diversity in the primate eye. (2000) (30)
- Hormonal effects on the neural retina: induction of glutamine synthetase by cyclic-3',5'-AMP. (1971) (30)
- The steroid induction of glutamine synthetase in chick embryo retinas in culture. A possible role of corticosteroid-binding globulin. (1969) (30)
- 8 – Retinoids in Ocular Tissues: Binding Proteins, Transport, and Mechanism of Action (1982) (30)
- Expression of guanylate cyclase-A mRNA in the rat retina: detection using polymerase chain reaction. (1992) (30)
- Immunomodulation of experimental autoimmune uveoretinitis by intravenous injection of uveitogenic peptides. (1992) (29)
- Retinol receptors in corneal epithelium, stroma and endothelium. (1977) (29)
- Cyclic nucleotide content and phosphodiesterase activity in the rds mouse (020/A) retina. (1984) (29)
- Neurotrophic activity of interphotoreceptor matrix on human Y79 retinoblastoma cells (1992) (28)
- Retinal pigment epithelial cell differentiation in vitro. Influence of culture medium. (1980) (27)
- Transplantation of Y79 cells into rat eyes: an in vivo model of human retinoblastomas. (1993) (27)
- Recent developments in studies on biological functions of vitamin A in normal and transformed tissues (1979) (27)
- Multipotential differentiation of human Y-79 retinoblastoma cells in attachment culture. (1987) (27)
- Heme oxygenase: expression in human retina and modulation by stress agents in a human retinoblastoma cell model system. (1992) (27)
- Uveitogenic potential of lymphocytes sensitized to interphotoreceptor retinoid-binding protein. (1987) (26)
- A quantitative system for studying phagocytosis in pigment epithelium tissue culture. (1979) (26)
- Immunohistochemical analysis of experimental autoimmune uveoretinitis (EAU) induced by interphotoreceptor retinoid-binding protein (IRBP) in the rat. (1987) (26)
- Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci. (1992) (26)
- An estrogen receptor repressor induces cataract formation in transgenic mice (2002) (26)
- Insulin and IGF-1 binding in chick sclera. (1990) (26)
- Control of retinoblastoma cell growth by differentiating agents: current work and future directions. (1986) (25)
- Cyclic nucleotides vary by area in the retina and pigmented epithelium of the human and monkey. (1980) (25)
- SOME FACTORS AFFECTING THE UPTAKE, BINDING AND RETENTION OF [3H]CORTISOL BY THE CHICK EMBRYO RETINA AS RELATED TO ENZYME INDUCTION (1973) (25)
- Structural Analysis of the Human (1994) (25)
- Analysis of the pivotal residues of the immunodominant and highly uveitogenic determinant of interphotoreceptor retinoid-binding protein. (1991) (25)
- Serial adoptive transfer of experimental autoimmune uveoretinitis in rats. (1990) (25)
- Estradiol-receptors of the rat uterus: interaction of the cytoplasmic estrogen-receptor with DNA in vitro. (1972) (24)
- An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. (2016) (24)
- Ocular Drug Delivery Systems : Barriers and Application of Nanoparticulate Systems (2012) (24)
- Characterization and novel activation of 72-kDa metalloproteinase in retinal interphotoreceptor matrix and Y-79 cell culture medium. (1994) (24)
- Study of a fatty acid binding site of interphotoreceptor retinoid-binding protein using fluorescent fatty acids. (1993) (23)
- Immunoelectron microscopic localization of photoreceptor-specific markers in the monkey retina. (1987) (23)
- Letter: Phosphodiesterase: an important role in cyclic nucleotide regulation in the retina. (1973) (23)
- Invasive activity, spreading on and chemotactic response to laminin are properties of high but not low metastatic mouse osteosarcoma cells. (1991) (23)
- Interphotoreceptor retinoid binding protein (IRBP) enhances rhodopsin regeneration in the experimentally detached retina. (1993) (23)
- Uveitis induced in primates by IRBP: humoral and cellular immune responses. (1987) (23)
- Steroid-protein interactions. XXVI. Studies on the polymeric nature of the corticosteroid-binding globulin of the rabbit. (1972) (22)
- cDNA clones encoding bovine interphotoreceptor retinoid binding protein. (1985) (22)
- Uptake of oestradiol by the rabbit hypothalamus. Specificity of binding by nuclei in vitro. (1970) (22)
- Advances in glaucoma treatment and management: neurotrophic agents. (2012) (22)
- Artificial sight : basic research, biomedical engineering, and clinical advances (2007) (21)
- Retinoblastoma. A clinical, immunohistochemical, and electron microscopic case report. (1986) (21)
- Differential temporal and spatial expression of insulin-like growth factor binding protein-2 in developing chick ocular tissues. (1995) (21)
- Behavior of human retinoblastoma cells in tissue culture (1987) (21)
- Structural organization and chromosomal localization of the human ribosomal protein L9 gene. (1996) (21)
- Repeated determinants within the retinal interphotoreceptor retinoid-binding protein (IRBP): immunological properties of the repeats of an immunodominant determinant. (1990) (21)
- Interspecies conservation of structure of interphotoreceptor retinoid-binding protein. Similarities and differences as adjudged by peptide mapping and N-terminal sequencing. (1986) (20)
- Effects of dihydrotestosterone on the synthesis of nucleic acid and ATP in prostatic nuclei. (1969) (20)
- Effects of laminin on attachment, growth and differentiation of cultured Y-79 retinoblastoma cells. (1988) (20)
- Studies on the differentiation of retinal pigmented epithelium cells in culture. (1975) (19)
- Vitamin A receptors. II. Characteristics of retinol binding in chick retina and pigment epithelium. (1977) (19)
- A role for DNA in the formation of nuclear estradiol-receptor complex in a cell-free system. (1971) (19)
- Interphotoreceptor retinoid-binding protein (IRBP) in progressive rod-cone degeneration (prcd)--biochemical, immunocytochemical and immunologic studies. (1991) (19)
- Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array. (2011) (19)
- Monkey retinal pigment epithelial cells in vitro synthesize, secrete, and degrade insulin‐like growth factor binding proteins (1992) (19)
- Characterization of glucose transport by cultured chick pigmented epithelium. (1981) (19)
- Interactions between cortisol or corticosterone and fractions of rat thymus, brain and heart cell. (1966) (19)
- Neurotransmitter-related features of the retinal pigment epithelium (1983) (19)
- Hypomethylation of the interphotoreceptor retinoid-binding protein (IRBP) promotor and first exon is linked to expression of the gene. (1990) (19)
- Coexpression of neuronal, glial, and major histocompatibility complex class II antigens on retinoblastoma cells. (1988) (19)
- Immune responses to peptides derived from the retinal protein IRBP: immunopathogenic determinants are not necessarily immunodominant. (1989) (18)
- Immunocytochemical demonstration of interphotoreceptor retinoid-binding protein in cerebellar medulloblastoma (2004) (18)
- Monkey interphotoreceptor retinoid-binding protein (IRBP): isolation, characterization and synthesis. (1985) (18)
- Inherited rod-cone dysplasia: abnormal distribution of cyclic GMP in visual cells of affected Irish setters. (1988) (18)
- Light deprivation profoundly affects gene expression of interphotoreceptor retinoid-binding protein in the mouse eye. (1994) (18)
- Retinitis pigmentosa with segmental massive retinal gliosis. An immunohistochemical, biochemical, and ultrastructural study. (1987) (17)
- Strychnine-insensitive glycine receptors in embryonic chick retina: characteristics and modulation of NMDA neurotoxicity (1992) (17)
- Human retinoblastoma cells express αB-crystallin in vivo and in vitro (1993) (17)
- Uveitis and immune responses in primates immunized with IRBP-derived synthetic peptides. (1990) (17)
- Purification and assay of interphotoreceptor retinoid-binding protein from the eye. (1990) (16)
- mRNA for interphotoreceptor retinoid-binding protein (IRBP): distribution and size diversity in vertebrate species. (1989) (16)
- Stimulation in vitro of lymphocytes for induction of uveoretinitis without any significant proliferation. (1990) (16)
- Alteration in gene expression at the onset of human Y-79 retinoblastoma cell differentiation (1985) (16)
- Unusual immunologic properties of the uveitogenic interphotoreceptor retinoid-binding protein-derived peptide R23. (1991) (16)
- Anomalous insulin-binding activity in the bovine neural retina: a possible mechanism for regulation of receptor binding specificity. (1988) (16)
- Synthesis and secretion of interphotoreceptor retinoid‐binding protein (IRBP) by isolated normal and rd mouse retinal photoreceptor neurons in culture (1989) (15)
- Differential retinoid binding in chick pigment epithelium and choroid. (1979) (15)
- A glycoprotein binding retinoids and fatty acids is present in Drosophila. (1994) (15)
- Cytokine-induced modulation of cellular proteins in retinoblastoma. Analysis by flow cytometry. (1991) (15)
- Light-induced phosphorylation of rod outer segments by guanosine triphosphate. (1975) (15)
- Redistribution and reduction of interphotoreceptor retinoid-binding protein during ocular coronavirus infection. (1992) (15)
- Acute Variations in Retinal Vascular Oxygen Content in a Rabbit Model of Retinal Venous Occlusion (2012) (14)
- Oxidative Damage and Responses in Retinal Nuclei Arising from Intense Light Exposure (1995) (14)
- Vitreal oxygenation in retinal ischemia reperfusion. (2011) (14)
- Differential control of protein kinase activities of the retinal photoreceptor. Cation effects on phosphorylation by adenosine and guanosine 5'-triphosphates. (1980) (14)
- Postnatal development of photoreceptor-specific proteins in mice with hereditary retinal degeneration. An immunocytochemical study. (1990) (14)
- Retinitis pigmentosa: immunohistochemical and biochemical studies of the retina. (1986) (14)
- The molecular biology of IRBP: application to problems of uveitis, protein chemistry, and evolution. (1991) (13)
- Developmental expression of the RI subunit of cyclic AMP-dependent protein kinase in retina. (1989) (13)
- Identification and partial characterization of a proteinase specific for insulin-like growth factor binding protein-3 in aqueous and vitreous humors. (1995) (13)
- Glucose oxidation in the chick cornea: effect of diamide on the pentose shunt. (1978) (12)
- Synthesis and secretion of interphotoreceptor retinoid-binding protein (IRBP) and developmental expression of IRBP mRNA in normal and rd mouse retinas. (1992) (12)
- Hereditary retinal degenerations in the dog: specificity of abnormal cyclic nucleotide metabolism to diseases of arrested photoreceptor development. (1982) (12)
- Soluble-binding proteins for docosahexaenoic acid are present in neural retina. (1995) (12)
- Isolation of candidate genes for macular degeneration using an improved solid-phase subtractive cloning technique. (1995) (12)
- Qualitative and quantitative analysis of cytosol retinoid binding proteins in human skin. (1985) (12)
- Cellular immune responses to retinal antigens in retinitis pigmentosa (2004) (11)
- INTRAVITREAL AND SUBRETINAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR (tPA) IN THE TREATMENT OF EXPERIMENTALLY CREATED RETINAL VEIN OCCLUSION IN RABBITS (2008) (11)
- In vitro studies on shedding and phagocytosis of rod outer segments in the rat retina: effect of oxygen concentration. (1982) (11)
- Modulators of cyclic AMP in monolayer cultures of Y-79 retinoblastoma cells: partial characterization of the response with VIP and glucagon. (1984) (11)
- An early decrease in interphotoreceptor retinoid-binding protein gene expression in Abyssinian cats homozygous for hereditary rod-cone degeneration (1994) (11)
- Reduced level of interphotoreceptor retinoid-binding protein (IRBP), a possible cause for retinal degeneration in the Abyssinian cat (1989) (11)
- Pigment epithelial cells in culture. Metabolic pathways required for phagocytosis. (1981) (11)
- Effect of multiple injections of small divided doses vs single injection of intravitreal bevacizumab on retinal neovascular model in rabbits (2009) (11)
- Decomposition of cortisol-4-14C to 11β-hydroxyandrost-4-ene-3, 17-dione-4-14C (1967) (11)
- Nuclear Uptake of Retinoids: Autoradiographic Evidence in Retinoblastoma Cells In Vitro (1980) (11)
- Pentose shunt activity in developing chick retina and pigment epithelium: a switch in biochemical expression in cultured pigment epithelial cells. (1978) (10)
- Retinoblastoma: messenger RNA for interphotoreceptor retinoid binding protein. (1992) (10)
- Mutation analysis and loss of heterozygosity of PEDF in central nervous system primitive neuroectodermal tumors (1997) (10)
- Vitamin A receptors. I. Comparison of retinol binding to serum retinol-binding protein and to tissue receptors in chick retina and pigment epithelium. (1977) (10)
- ‘Piggyback’ chromatography: assay for guanylate cyclase in retina and other neural tissue (1974) (9)
- Cytosol binding of retinyl palmitate and palmitic acid in pigment epithelium and retina. (1981) (9)
- Postnatal development of photoreceptor proteins in mutant mice and Abyssinian cats with retinal degeneration. (1989) (9)
- In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance. (2013) (9)
- Interphotoreceptor Retinoid-Binding Protein: A Link Between Retinal Rod Photoreceptor Cells and Pineal Gland (1986) (9)
- Y-79 retinoblastoma cells: isolation and characterization of clonal lineages. (1989) (9)
- Recombinant Forms of the Neurotrophic Factor Pigment Epithelium-Derived Factor Activate Cellular Metabolism and Inhibit Proliferation of the RAW Macrophage Cell Line (1999) (9)
- Separation of retinoid receptors from cultured retinoblastoma cells. (1978) (9)
- Phagocytosis of rod outer segments by cultured epithelial cells (1981) (9)
- Structural organization and expression of the human phosphatidylinositol-specific phospholipase C beta-3 gene. (1995) (9)
- Modulation of retinoblastoma cell characteristics by hexamethylene bis-acetamide and other differentiating agents in culture. (1993) (9)
- IRBP from bovine retina is poorly uveitogenic in guinea pigs and is identical to A-antigen. (1987) (9)
- Organization and transcription of canine (CAC)n sequences. (1991) (9)
- Interphotoreceptor retinoid-binding protein levels in subretinal fluid from rhegmatogenous retinal detachment and retinopathy of prematurity. (1988) (8)
- The pentose phosphate pathway in developing chick cornea. (1978) (8)
- Human retinoblastoma cells express alpha B-crystallin in vivo and in vitro. (1993) (8)
- Fluorescein angiography, optical coherence tomography, and histopathologic findings in a VEGF165 animal model of retinal angiogenesis (2012) (8)
- Extracellular cGMP phosphodiesterase related to the rod outer segment phosphodiesterase isolated from bovine and monkey retinas. (1985) (7)
- Partial purification and characterization of arylamine N-acetyltransferase in bovine retina. (1992) (7)
- Preface: Sight Restoration Through Stem Cell Therapy. (2016) (7)
- Interferon-γ enhances the expression of retinal S-antigen, a specific neuronal cel marker (1990) (7)
- A review of the role of cyclic GMP in neurological mutants with photoreceptor dysplasia. (1985) (7)
- An examination of the efficiency of glucose and glutamine as energy sources for cultured chick pigment epithelial cells (1984) (7)
- Insulin-like growth factors and their binding proteins in the developing eye (1997) (7)
- Immunological features of synthetic peptides derived from the retinal protein IRBP: differences between immunodominant and non-dominant peptides. (1990) (7)
- Ultrastructural and biochemical analysis of sperm flagella from an infertile man with a rod-dominant retinal degeneration. (1996) (7)
- Abnormal expression of the RI subunit of cyclic AMP-dependent protein kinase in Y-79 retinoblastoma cells. (1989) (6)
- Development of phosphodiesterase activity in the chick retina. (1974) (6)
- Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells (1993) (6)
- The existence of two completely distinct antigenic sites within a decapeptide. (1992) (6)
- Human gene for the RNA polymerase II seventh subunit (hsRPB7): structure, expression and chromosomal localization. (1997) (6)
- Phosphorylation of interphotoreceptor retinoid-binding protein (IRBP) (1988) (6)
- Cyclic GMP phosphodiesterase activator: Involvement in a hereditary retinal degeneration (1980) (6)
- Studies on a specific glucocorticoid-hormone receptor in the developing chick retina. (1974) (6)
- Editorials on recent advances: Retinitis pigmentosa and retinol-binding protein. (1974) (6)
- Assay of tubulin acetyltransferase activity in subcellular tissue fractions. (1994) (6)
- Vitreous and aqueous humors contain a latent proteinase activity that abolishes IGF binding to specific IGF binding proteins. (1995) (6)
- Key needs and opportunities for treating glaucoma. (2012) (6)
- Retinal pigment epithelium in culture demonstrates a distinct beta-adrenergic receptor. (1984) (5)
- Identification and characterization of arylamine N-acetyltransferase activity from the bovine retinal pigment epithelium. (1993) (5)
- Studies on abnormal cyclic GMP metabolism in animal models of retinal degeneration: genetic relationships and cellular compartmentalization. (1987) (5)
- In vivo cGMP levels in frog photoreceptor cells as a function of light exposure. (1986) (5)
- Beyond basic research for inherited and orphan retinal diseases: successes and challenges. (2005) (5)
- Animal mutants of hereditary retinal degeneration: general considerations and studies on defects in cyclic nucleotide metabolism (1991) (5)
- Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion. (2012) (5)
- Laminin: An initiating role in retinoblastoma cell attachment and differentiation (1986) (4)
- Glutamine synthetase in the normal human retina. (1971) (4)
- Characterization of an interphotoreceptor matrix (IPM) metalloproteinase-timp-like inhibitor system (1992) (4)
- Modulation of y-79 retinoblastoma cell-differentiation and IRBP expression by dibutyryl-cyclic-amp and laminin. (1993) (4)
- Identification of heat shock proteins binding to an immunodominant uveitopathogenic peptide of IRBP. (1994) (4)
- Maximal GABA and muscimol binding to high-affinity sites differ in physiological and in non-physiological buffers (1986) (4)
- Adenine nucleotide and P-creatine levels in layers of frog retina as a function of dark and light adaptation. (1985) (4)
- Identification of arylamine N-acetyltransferase activity in the bovine lens. (1995) (4)
- Cyclic nucleotides and protein kinase systems in the developing chick retina and pigment epithelium. (1978) (4)
- Surmountable challenges in translating pigment epithelium-derived factor (PEDF) therapy from animal models to clinical trials for retinal degenerations. (2005) (3)
- Neural Retinal-Pigment Epithelial Interactions: Morphological Characteristics of Cells Grown Together in Culture (1978) (3)
- Tissue culture of chick embryonic choroidal cells: cell aggregation and pigment accumulation. (1982) (3)
- A possible receptor for retinol in corneal epithelium. (1977) (3)
- A polymerase chain reaction‐based method for the identification of DNA samples from common vertebrate species (1994) (3)
- Retinal dystrophies : functional genomics to gene therapy (2003) (3)
- Radioanalytic estimation of amplification products generated by reverse transcription PCR using [alpha-33P] deoxyribonucleoside triphosphate. (1993) (3)
- Cloning of a polymorphic canine genetic marker which maps to human chromosome 9. (2009) (2)
- Calcium-induced spikes in cultured pigment epithelium of chick retina. (1976) (2)
- Progress in retinal research (1982) (2)
- Interferon-gamma enhances the expression of retinal S-antigen, a specific neuronal cell marker. (1990) (2)
- Distribution of the regulatory subunit of type II cAMP-dependent protein kinase in Y-79 retinoblastoma cells. Effect of butyrate. (1986) (2)
- Retinal pigment epithelial cell differentiation in vitro (2017) (2)
- Mechanisms of Hereditary Visual Cell Disease (1985) (2)
- Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod outer segments (1974) (2)
- Dopamine and myopia. (1990) (2)
- - Nanoparticle-Based Therapeutics: An Overview (2012) (2)
- Safety and Functionality of a Retinal Pigment Epithelium Monolayer Transplantation derived from Human Embryonic Stem Cells in Yucatan Mini-Pigs (2013) (2)
- Molecular genetics of interphotoreceptor retinoid-binding protein (1988) (2)
- Induction of unresponsiveness in adult rats by immunodominant and nondominant peptides. (1993) (2)
- High-resolution OCT: an innovative tool for posterior segment imaging. (2012) (2)
- Growth Factors In The Retina (1997) (2)
- A specific cyclic GMP phosphodiesterase of the retinal interphotoreceptor matrix. (1985) (2)
- Safety outcome of subretinal human embryonic stem cell-derived pigment epithelium (hESC-RPE) transplantation in Yucatan mini-pigs with oral or intravenous immunosupression. (2014) (2)
- Retinal degenerations of hereditary, viral and autoimmune origins: Studies on opsin and IRBP (1994) (2)
- - Eye Anatomy, Physiology, and Ocular Barriers: Basic Considerations for Drug Delivery (2012) (2)
- A NOVEL MODEL OF CHOROIDAL NEOVASCULARIZATION IN RABBITS (2014) (1)
- Characteristics of protein tyrosine kinase activities of Y-79 retinoblastoma cells and retina. (1985) (1)
- Insulin-like growth factor binding proteins (IGF-BPs): High levels in vitreous and increases in human diabetics and animal models of diabetes (1992) (1)
- Suprachoroidal Implantation of Multiple Electrode Arrays in the Rabbit Eye (2009) (1)
- Effects of diamide on cyclic nucleotide levels in rat retina. (1984) (1)
- Ocular Compartment Drug Delivery (2012) (1)
- The molecular biology of the retina. Basic and clinically relevant studies. Proceedings of the Eighth Annual International Society of Eye Research Meeting. San Francisco, California, September 1-5, 1988. (1991) (1)
- Retinal pigment epithelium contains a distinctive strychnine-binding site (1982) (1)
- Drug Delivery Systems (2012) (1)
- Phorbol ester and light-induced endogenous phosphorylation of rat retinal rod outer segment (ROS) proteins (1986) (1)
- Molecular Analysis of the Human PEDF Gene, a Candidate Gene for Retinal Degeneration: Localization To 17p13.3 (1997) (1)
- Screening of a Large Cohort of Leber Congenital Amaurosis and Retinitis Pigmentosa Patients Identifies Novel LCA5 Mutations and New Genotype–Phenotype Correlations (2014) (1)
- CYTOSOL BINDING OF RETINYL PALMITATE AND PALMITIC ACID IN PIGMENT EPITHELIUM (PE) AND RETINA (1981) (1)
- Morphologic description of Y79 retinoblastoma cells by a simple image analysis system (1990) (1)
- Retinal cyclic GMP and AMP in rod-cone dysplasia: comparison of assays in fixed and unfixed retinal tissues. (1990) (1)
- A Model of Tractional Retinal Detachment in the Rabbit Eye (2013) (0)
- originating from pigment factor Hemmug of glial proliferation (1995) (0)
- Metabolic inhibitors and glucose oxidation in developing chick cornea. (1979) (0)
- Recombinant Retinal Pigment Epithelium-Derived Factor: Its Purification from Overexpressing Escherichia Coli and Survival Effect on Induced Apoptosis in Cerebellar Granule Neurons (1995) (0)
- Chronic Epiretinal Array Implant in Advanced Retinitis Pigmentosa: Morphometric Analysis of Retina in Post-Mortem Eyes (2009) (0)
- Morphological and Functional Evaluation of hESC-RPE Cell Suspension Injection in RCS Rats (2012) (0)
- Overarching themes. (2012) (0)
- Decomposition of cortisol-4-14C to 11-beta-hydroxyandrost-4-ene-3,17-dione-4-14C. (1967) (0)
- Pigmented epithelial (PEDF) factor: characterization, genomic organization and sequence of the PEDF gene (1995) (0)
- Photoresponsive Polymers for Ocular Drug Delivery (2012) (0)
- Expression and tissue specificity of a retinoid binding protein (1990) (0)
- Oxygenation of the Anterior Vitreous in a Rabbit Eye Model of Ischemia Reperfusion (2009) (0)
- XXVI. STUDIES ON THE POLYMERIC 1\SATURE OF THE CORTICOSTEROID~RINDING GLOBULInT OF THE RABBIT* (2003) (0)
- Evaluation of Ultrasound-Assisted Thrombolysis Using Nontargeted Ultrasound Contrast Agents in a Model of Retinal Vein Occlusion (2012) (0)
- Estrogen Receptors in the Hypothalamus1 (1971) (0)
- Fine mapping of an Autosomal Dominant Retinitis Pigmentosa (ADRP) locus on chromosome 17p13.3 and analysis of a candidate gene (1996) (0)
- Immunoelectron microscopy of retinoblastoma (1987) (0)
- Migration of y 79 retinoblastoma cells to a basement membrane extract and to purified lamin ln (1988) (0)
- Retina Evaluation of Ultrasound-Assisted Thrombolysis Using Custom Liposomes in a Model of Retinal Vein Occlusion (2012) (0)
- Acknowledgment to reviewers (1996) (0)
- SECTION II: OVERARCHING THEMES Overarching Themes (2017) (0)
- Retinal autoimmunity induced by a cell line specific for interphotoreceptor retinoid-binding protein (IRBP) (1987) (0)
- Retinal Prosthetic Devices (2007) (0)
- Mature Retina (2007) (0)
- Variability of Vascular Oxygen Content in a Rabbit Retinal Vein Occlusion Model: A Study Using Hyperspectral Computer Tomographic Imaging Spectroscopy (2012) (0)
- Late abstracts 186–187 (2005) (0)
- Long-term Efficacy and Safety of an RPE Cell Monolayer Derived From Human Embryonic Stem Cells Implanted into the Subretinal Space of the RCS Rat (2013) (0)
- On presentation of the Proctor Award of the Association for Research in Vision and Ophthalmology to Drs. Waldon Wacker and Robert Nussenblatt. (1991) (0)
- Molecular characterization of a human gene for S28 ribosomal binding protein (1994) (0)
- CHAPTER 20 – Degenerative Retinopathies (2008) (0)
- Neurotrophic activity and gene analysis of a pigment epithelium-derived factor (PEDF) (1992) (0)
- An early decrease in IRBP gene expression in Abyssinian cats homozygous for progressive retinal atrophy (1992) (0)
- The Effect of Controlled Electrolysis in the Vitreous for Pre-Retinal Oxygenation (2010) (0)
- Y-79 retinoblastoma cells differentiate in the presence of laminin but lack “classic” laminin receptors (1992) (0)
- Introducing Gustavo D. Aguirre, the 2017 Recipient of the Proctor Medal. (2017) (0)
- P 381 RPE cell death in culture as followed by fluorescent probes (1995) (0)
- Purification of multiple forms of rhodopsin kinase (1984) (0)
- Drug Delivery to the Vitreous Humor (2012) (0)
- Vision Research: Editorial (2003) (0)
- Rapid PCR-based construction of specifically enriched libraries from small retina samples. (1992) (0)
- Characterization of human B cell proteins binding specifically to uveitopathogenic peptide 1169-1191 of bovine IRBP. (1994) (0)
- Injury and Repair: Prostheses (2010) (0)
- Differences in arylalkylamine N-acetyltransferase activity between inflammatory disease-susceptible Lewis and -resistant Fischer rats. (1995) (0)
- Factor of pigmented epithelium (PEDF) characterization, genomic organization and sequence of the PEDF gene (1995) (0)
- Nanosuspensions in Ocular Drug Delivery Systems (2012) (0)
- (54) RETINAL PIGMENTED EPITHELIUM FOREIGN PATENT DOCUMENTS DERVED NEUROTROPHC FACTOR EP O412554 B1 11F1994 (2017) (0)
- The Effects of Bevacizumab in VEGF-Injected Rabbit Eyes (2007) (0)
- A Fond Farewell (2002) (0)
- Surface Modulation of Nanoparticles (2012) (0)
- In Vivo Imaging of hESC-RPE Implanted in the RCS Rat Using InfraRed Reflectance (2013) (0)
- Characterization of the fatty acid binding site of interphotoreceptor retinol-binding protein (IRBP) using fluorescent fatty acids (1992) (0)
- Retinoblostomo : A Primitive Tumor With Multipotentioi Characteristics (0)
- Variation in Retinal Vascular Oxygen Content Among Human Patients: A Study Using Computed Tomographic Imaging Spectroscopy (2012) (0)
- The Role of Alpha Crystallins on Safety of Acute Electrical Retinal Stimulation in Mice (2010) (0)
- Deletion mapping and candidate gene analysis of chromosome 17 in primitive neuroectodermal tumors of the CNS (1995) (0)
- Protein tyrosine phosphorylation activity in human retina and Y-79 retinoblastoma cells: Nucleotide specificity and modulation by retinoblastoma-derived growth factor (1984) (0)
- Preface: A focus on new treatments for blinding ocular diseases. (2012) (0)
- Phosphorylation of bovine interphotoreceptor retinoid-binding protein (IRBP) (1986) (0)
- Distribution of the Regulotory Subunit of Type II cAMP-Dependent Protein Kinose in Y-79 Retinoblostomo Cells Effect of Buryrare (2005) (0)
- PET Study of Light and Transcorneal Electrical Stimulation in Humans (2009) (0)
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