Gregory John Del Zoppo
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Gregory John Del Zoppo's AcademicInfluence.com Rankings
Gregory John Del Zoppophilosophy Degrees
Philosophy
#9046
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#12543
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Logic
#6047
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#7526
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Gregory John Del Zoppobiology Degrees
Biology
#12378
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#15849
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Neuroscience
#2077
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#2135
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Philosophy Biology
Gregory John Del Zoppo's Degrees
- PhD Neuroscience Stanford University
Why Is Gregory John Del Zoppo Influential?
(Suggest an Edit or Addition)Gregory John Del Zoppo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials (2014) (1828)
- Guidelines for the Early Management of Patients With Ischemic Stroke: A Scientific Statement From the Stroke Council of the American Stroke Association (2003) (1319)
- PROACT: a phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. PROACT Investigators. Prolyse in Acute Cerebral Thromboembolism. (1998) (1226)
- Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke (1992) (993)
- Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. (2001) (992)
- Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis (2012) (890)
- Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. (2009) (805)
- Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. (1988) (795)
- Polymorphonuclear Leukocytes Occlude Capillaries Following Middle Cerebral Artery Occlusion and Reperfusion in Baboons (1991) (747)
- Hemorrhagic transformation within 36 hours of a cerebral infarct: relationships with early clinical deterioration and 3-month outcome in the European Cooperative Acute Stroke Study I (ECASS I) cohort. (1999) (652)
- Cerebral Microvessel Responses to Focal Ischemia (2003) (599)
- Role for Matrix Metalloproteinase 9 after Focal Cerebral Ischemia: Effects of Gene Knockout and Enzyme Inhibition with BB-94 (2000) (593)
- Matrix Metalloproteinases Increase Very Early during Experimental Focal Cerebral Ischemia (1999) (561)
- Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). (1994) (520)
- Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update a scientific statement from the Stroke Council of the American Heart Association/American Stroke Association. (2005) (470)
- Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome (2004) (464)
- Hemorrhagic transformation in acute ischemic stroke. Potential contributing factors in the European Cooperative Acute Stroke Study. (1997) (447)
- Neuroradiologic evaluation of patients with acute stroke treated with recombinant tissue plasminogen activator. The rt-PA Acute Stroke Study Group. (1993) (433)
- P‐Selectin and Intercellular Adhesion Molecule‐1 Expression After Focal Brain Ischemia and Reperfusion (1994) (422)
- Brief report: reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. (1993) (409)
- Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. (1995) (383)
- Local intra-arterial fibrinolytic therapy in acute carotid territory stroke. A pilot study. (1988) (382)
- Inhibition of Polymorphonuclear Leukocyte Adherence Suppresses No‐Reflow After Focal Cerebral Ischemia in Baboons (1992) (371)
- Advances in the vascular pathophysiology of ischemic stroke. (2000) (335)
- Hemorrhagic Transformation and Microvascular Integrity during Focal Cerebral Ischemia/Reperfusion (1996) (306)
- Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. (2001) (270)
- Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time window. (1995) (269)
- Focal Cerebral Ischemia Induces Active Proteases That Degrade Microvascular Matrix (2004) (265)
- Ischaemic damage of brain microvessels: inherent risks for thrombolytic treatment in stroke (1998) (264)
- Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier (2013) (235)
- Thrombolysis for acute ischaemic stroke. (2014) (232)
- Thrombolytic therapy in stroke: possibilities and hazards. (1986) (224)
- Integrin-matrix interactions in the cerebral microvasculature. (2006) (215)
- Microglial Activation and Matrix Protease Generation During Focal Cerebral Ischemia (2007) (212)
- Fibrin Contributes to Microvascular Obstructions and Parenchymal Changes During Early Focal Cerebral Ischemia and Reperfusion (1994) (205)
- Experimental acute thrombotic stroke in baboons. (1986) (190)
- Examination of Several Potential Mechanisms for the Negative Outcome in a Clinical Stroke Trial of Enlimomab, a Murine Anti-Human Intercellular Adhesion Molecule-1 Antibody: A Bedside-to-Bench Study (2001) (164)
- Experimental Antileukocyte Interventions in Cerebral Ischemia (1996) (164)
- Sulfonylureas Improve Outcome in Patients With Type 2 Diabetes and Acute Ischemic Stroke (2007) (160)
- The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke: The CLEAR Stroke Trial (2008) (153)
- Inflammation after stroke: is it harmful? (2001) (152)
- Rapid Loss of Microvascular Integrin Expression during Focal Brain Ischemia Reflects Neuron Injury (2001) (147)
- Localization of tissue plasminogen activator in the endothelium of a limited number of vessels. (1994) (143)
- Activated Microvessels Express Vascular Endothelial Growth Factor and Integrin αvβ3 During Focal Cerebral Ischemia (1999) (137)
- Thrombolytic agents in the treatment of stroke. (1990) (137)
- Heterogeneity in the penumbra (2011) (136)
- E-selectin appears in nonischemic tissue during experimental focal cerebral ischemia. (1996) (133)
- Activation Systems for Latent Matrix Metalloproteinase-2 are Upregulated Immediately after Focal Cerebral Ischemia (2003) (125)
- Microvascular changes during cerebral ischemia and reperfusion. (1994) (124)
- Interendothelial Claudin-5 Expression Depends on Cerebral Endothelial Cell–Matrix Adhesion by β1-Integrins (2011) (123)
- Stroke and neurovascular protection. (2006) (121)
- Hemorrhagic Transformation of Cerebral Infarction – Possible Mechanisms (1999) (119)
- Rapid Differential Endogenous Plasminogen Activator Expression After Acute Middle Cerebral Artery Occlusion (2001) (118)
- The beneficial effect of intracarotid urokinase on acute stroke in a baboon model. (1986) (117)
- DNA scission after focal brain ischemia. Temporal differences in two species. (1997) (115)
- Integrin alphavbeta3 is expressed in selected microvessels after focal cerebral ischemia. (1996) (113)
- Advancing the Study of Stroke in Women: Summary and Recommendations for Future Research From an NINDS-Sponsored Multidisciplinary Working Group (2006) (107)
- Responses of Endothelial Cell and Astrocyte Matrix-Integrin Receptors to Ischemia Mimic Those Observed in the Neurovascular Unit (2008) (101)
- Microglial Cell Activation is a Source of Metalloproteinase Generation during Hemorrhagic Transformation (2012) (100)
- Intracranial hemorrhage after coronary thrombolysis with tissue plasminogen activator. (1992) (98)
- Fibronectin- and Vitronectin-Induced Microglial Activation and Matrix Metalloproteinase-9 Expression Is Mediated by Integrins α5β1 and αvβ51 (2007) (95)
- Tissue Factor Contributes to Microvascular Defects After Focal Cerebral Ischemia (1993) (94)
- Hyperfibrinogenemia and functional outcome from acute ischemic stroke. (2009) (93)
- Models of focal cerebral ischemia in the nonhuman primate. (2003) (93)
- Use of gel zymography to examine matrix metalloproteinase (gelatinase) expression in brain tissue or in primary glial cultures. (2012) (87)
- Acute vertebral-basilar thrombosis. Angiologic-clinical comparison and therapeutic implications. (1986) (86)
- Vascular matrix adhesion and the blood-brain barrier. (2006) (86)
- Ancrod in Acute Ischemic Stroke: Results of 500 Subjects Beginning Treatment Within 6 Hours of Stroke Onset in the Ancrod Stroke Program (2009) (84)
- The neurovascular unit, matrix proteases, and innate inflammation (2010) (84)
- Hemorrhagic transformation following tissue plasminogen activator in experimental cerebral infarction. (1990) (84)
- Tissue Factor Localization in Non-Human Primate Cerebral Tissue (1992) (82)
- Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion. (1997) (78)
- The Rapid Decrease in Astrocyte-Associated Dystroglycan Expression by Focal Cerebral Ischemia is Protease-Dependent (2008) (77)
- Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: Executive Summary. A Statement for Healthcare Professionals From the Neurocritical Care Society and the Society of Critical Care Medicine (2016) (77)
- Glibenclamide in Cerebral Ischemia and Stroke (2014) (75)
- The role of platelets in ischemic stroke (1998) (75)
- Microvascular responses to cerebral ischemia/inflammation. (1997) (73)
- Angiogenesis in the ischemic core: A potential treatment target? (2019) (73)
- Ultrastructural and temporal changes of the microvascular basement membrane and astrocyte interface following focal cerebral ischemia (2009) (73)
- Activated microvessels express vascular endothelial growth factor and integrin alpha(v)beta3 during focal cerebral ischemia. (1999) (73)
- Thrombolytic intervention in acute thrombotic and embolic stroke. (1991) (73)
- Thrombolysis for Acute Ischemic Stroke (2004) (70)
- Focal Cerebral Ischemia Preferentially Affects Neurons Distant from Their Neighboring Microvessels (2005) (70)
- In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the α6β4 integrin and dystroglycan (2010) (65)
- Integrin alpha(IIb)beta(3) inhibitor preserves microvascular patency in experimental acute focal cerebral ischemia. (2000) (64)
- Virchow's triad: the vascular basis of cerebral injury. (2008) (63)
- Distribution of Integrin-like Immunoreactivity on Primate Brain Microvasculature (1996) (58)
- “Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop (2016) (57)
- Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha5beta1 and alphavbeta5. (2007) (51)
- Neutrophil activation in smokers. (1996) (48)
- Why do all drugs work in animals but none in stroke patients? 1. Drugs promoting cerebral blood flow. (1995) (48)
- Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation (2016) (45)
- Acute anti‐inflammatory approaches to ischemic stroke (2010) (44)
- Exploratory Analysis of Glyburide as a Novel Therapy for Preventing Brain Swelling (2014) (40)
- Polymorphonuclear Leukocyte Behavior in a Nonhuman Primate Focal Ischemia Model (1994) (36)
- New options in anticoagulation for atrial fibrillation. (2011) (36)
- Alteration of fibrin network by activated protein C. (1994) (35)
- TIMP-1 attenuates blood–brain barrier permeability in mice with acute liver failure (2013) (34)
- Thrombolytic therapy in the treatment of stroke. (1997) (34)
- β1-integrin–matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability (2017) (34)
- Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review (2018) (34)
- Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials (2018) (31)
- Hematologic causes of intracerebral hemorrhage and their treatment. (1992) (31)
- Leukocyte involvement in vasomotor reactivity of the cerebral vasculature. (1994) (30)
- Hemostasis and Alterations of the Central Nervous System (2013) (25)
- Dabigatran Abrogates Brain Endothelial Cell Permeability in Response to Thrombin (2013) (24)
- The neurovascular unit in the setting of stroke (2010) (22)
- Inflammation and the neurovascular unit in the setting of focal cerebral ischemia. (2009) (22)
- Antiplatelet therapy in thrombotic thrombocytopenic purpura. (1987) (21)
- Immunomodulation strategies for preventing vascular disease of the brain and heart: workshop summary. (2006) (20)
- Relationship of Neurovascular Elements to Neuron Injury during Ischemia (2009) (19)
- Acute stroke--on the threshold of a therapy? (1995) (18)
- tPA: A neuron buster, too? (1998) (17)
- Polymorphonuclear neutrophil infiltration into ischemic infarctions: myth or truth? (2013) (17)
- In stroke, complement will get you nowhere (1999) (16)
- Multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke. The effect of periprocedural medication: acetylsalicylic acid, unfractionated heparin, both, or neither (MR CLEAN-MED). Rationale and study design (2020) (16)
- Recanalization and stroke outcome. (2007) (16)
- Antithrombotic Treatments in Acute Ischemic Stroke (2000) (16)
- Relevance of Focal Cerebral Ischemia Models Experience With Fibrinolytic Agents (1990) (15)
- Acute stroke treatment trials in the United States. Rethinking strategies for success. (1995) (15)
- Perioperative Management of Coagulation in Nontraumatic Intracerebral Hemorrhage (2013) (15)
- Thrombolysis for acute ischaemic stroke. (2009) (15)
- Fibrinogen Chains Intrinsic to the Brain (2019) (15)
- Blood/vessel interaction in coronary disease. (1984) (14)
- New interventions in cerebrovascular disease: the role of thrombolytic therapy and balloon angioplasty. (1996) (13)
- Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia? (2008) (13)
- Thrombolytic intervention in acute thrombotic and embolic stroke. (1991) (13)
- Ancrod: A Potential Treatment for Acute, Ischemic Stroke from Snake Venom (2006) (13)
- Approach to the treatment, characterization and diagnosis of an acquired auto‐antibody directed against factors prothrombin, factor X and factor IX: a case report and review of the literature (2012) (10)
- Thrombolysis for Acute Ischemic Stroke, Update August 2014 (2014) (10)
- Comparison of Large Animal Models for Acute Ischemic Stroke: Which Model to Use? (2022) (9)
- [Mechanisms for the development of intracranial hemorrhage. Possible implications for thrombolysis in cerebral infarct]. (1999) (9)
- Innate inflammation as the common pathway of risk factors leading to TIAs and stroke (2010) (9)
- Toward the Neurovascular Unit A Journey in Clinical Translation: 2012 Thomas Willis Lecture (2013) (9)
- Interventional use of plasminogen activators in central nervous system diseases. (1998) (8)
- Thrombolysis: From the Experimental Findings to the Clinical Practice (2003) (8)
- An Open, Multicenter Trial of Recombinant Tissue Plasminogen Activator in Acute Stroke: A Progress Report (1990) (8)
- Investigational use of tPA in acute stroke. (1988) (7)
- Lessons from stroke trials using anti-inflammatory approaches that have failed. (2004) (7)
- Thrombolysis for acute ischaemic stroke. (2000) (6)
- Translating interventions from ischemic stroke models to patients: the view in 2009. (2009) (6)
- Uptake of C5a by polymorphonuclear leukocytes (PMNs) after focal cerebral ischemia. I. Effect of tirilazad mesylate intervention on C5a uptake by PMNs. (1994) (6)
- Throwing out the thromboemboli. (2010) (6)
- Plasminogen Activators and Ischemic Stroke: Conditions for Acute Delivery (2013) (6)
- INTRA-ARTERIAL THROMBOLYTIC THERAPY IN ACUTE MIDDLE CEREBRAL ARTERY STROKE (1987) (4)
- Plasminogen activators in ischemic stroke: introduction. (2010) (4)
- Bleeding in the brain: Amyloid-beta may keep clots away. (2009) (4)
- Correction: Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome (2004) (4)
- Clinical trials in acute stroke (1998) (4)
- Aging and the neurovascular unit (2012) (3)
- Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. (2017) (3)
- Focal cerebral ischemia and hemostasis: a PAI‐1 conundrum (2005) (3)
- Exploring phlebotomy technique as a pre-analytical factor in proteomic analyses by mass spectrometry. (2015) (2)
- FIBRINOLYTIC THERAPY IN ACUTE VERTEBROBASILAR STROKE (1987) (2)
- Treatment of acute stroke. (1990) (2)
- [Regulating the responses of the neurovascular unit to focal ischemia]. (2010) (1)
- TIAs and the pathology of cerebral ischemia (2004) (1)
- Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial (2022) (1)
- Introduction to Thrombolysis and Acute Stroke Treatment: Preparing for the Next Decade (2012) (1)
- Thrombolysis in acute stroke. (1995) (1)
- Antithrombotic Therapy of Acute Stroke: Thrombolytic Agents (1997) (1)
- Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial (2022) (1)
- Thrombolytic therapy in cerebrovascular disease. (1988) (1)
- Intracerebral hemorrhage and thrombin-induced alterations in cerebral microvessel matrix (2022) (1)
- Contributors (2019) (0)
- Thrombolytic therapy in acute ischemic stroke. (1994) (0)
- [Fibrinolytic therapy in ischemic brain infarct]. (1987) (0)
- Hemostasis and cerebral metastases in a model system. (2021) (0)
- Extracranial cerebrovascular disease involving the arteries (1992) (0)
- Antithrombotic treatments in acute ischemic stroke. (1999) (0)
- Thrombin (2004) (0)
- [Ischemic stroke and the fate of cerebral microvessels]. (2012) (0)
- [Aiming for a breakthrough in therapy for cerebrovascular disorders]. (2010) (0)
- Thrombolysis and stroke management. (1993) (0)
- Antiplatelet Drugs in the Management of Cerebral Ischemia (2019) (0)
- Thrombin: maybe not so spellbinding. (2004) (0)
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