Gorō K. Kikuchi
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Gorō K. Kikuchibiology Degrees
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Molecular Biology
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Biochemistry
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Chemistry Biology
Gorō K. Kikuchi's Degrees
- PhD Biochemistry University of Tokyo
- Masters Chemistry University of Tokyo
- Bachelors Chemistry University of Tokyo
Why Is Gorō K. Kikuchi Influential?
(Suggest an Edit or Addition)Gorō K. Kikuchi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Heme oxygenase and heme degradation. (2003) (312)
- Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia. (2008) (281)
- The enzymatic synthesis of delta-aminolevulinic acid. (1958) (225)
- Purification and properties of heme oxygenase from pig spleen microsomes. (1978) (163)
- The glycine cleavage system: Composition, reaction mechanism, and physiological significance (1973) (151)
- Features of the reaction of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system. (1978) (135)
- Translocation of delta-aminolevulinate synthase from the cytosol to the mitochondria and its regulation by hemin in the rat liver. (1980) (99)
- Purification and properties of heme oxygenase from rat liver microsomes. (1979) (92)
- Oxygenated form of heme . heme oxygenase complex and requirement for second electron to initiate heme degradation from the oxygenated complex. (1980) (90)
- Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes. (1974) (85)
- Glycine metabolism in rat liver mitochondria. V. Intramitochondrial localization of the reversible glycine cleavage system and serine hydroxymethyltransferase. (1971) (81)
- Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. IV. Accumulation of the enzyme in the soluble fraction of rat liver. (1969) (73)
- Mechanism of allylisopropylacetamide-induced increase of -aminolevulinate synthetase in liver mitochondria. V. Mechanism of regulation by hemin of the level of -aminolevulinate synthetase in rat liver mitochondria. (1972) (68)
- Induction of heme oxygenase by hemin in cultured pig alveolar macrophages. (1978) (66)
- Glycine metabolism by rat liver mitochondria. Reconstruction of the reversible glycine cleavage system with partially purified protein components. (1974) (65)
- Evidence for the transcriptional inhibition by heme of the synthesis of delta-aminolevulinate synthase in rat liver. (1982) (65)
- The step of carbon monoxide liberation in the sequence of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system. (1982) (64)
- Majors pathways of serine and glycine catabolism in various organs of the rat and cock. (1973) (62)
- Major pathways of glycine and serine catabolism in rat liver. (1970) (59)
- Studies on relationships between structure and function of hemoglobin M-Iwate. (1966) (57)
- The mitochondrial glycine cleavage system. Purification and properties of glycine decarboxylase from chicken liver mitochondria. (1980) (57)
- Comparative study on major pathways of glycine and serine catabolism in vertebrate livers. (1972) (56)
- Purification and properties of biliverdin reductases from pig spleen and rat liver. (1979) (56)
- Defective glycine cleavage system in nonketotic hyperglycinemia. Occurrence of a less active glycine decarboxylase and an abnormal aminomethyl carrier protein. (1981) (55)
- Mechanism of increase of heme oxygenase activity induced by hemin in cultured pig alveolar macrophages. (1979) (54)
- Inhibition by hemin of in vitro translocation of chicken liver delta-aminolevulinate synthase into mitochondria. (1983) (53)
- Glycine metabolism by rat liver mitochondria. IV. Isolation and characterization of hydrogen carrier protein, an essential factor for glycine metabolism. (1974) (53)
- Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. II. Effects of hemin and bilirubin on enzyme induction. (1968) (52)
- Identification of a high affinity growth hormone receptor in rat adipocyte membranes. (1984) (51)
- Translational inhibition by heme of the synthesis of hepatic delta-aminolevulinate synthase in a cell-free system. (1983) (50)
- Mechanism of reversible glycine cleavage reaction in Arthrobacter globiformis. Function of lipoic acid in the cleavage and synthesis of blycine. (1976) (48)
- The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein. (1980) (48)
- Nonketotic Hyperglycinemia: Two Patients with Primary Defects of P-Protein and T-Protein, Respectively, in the Glycine Cleavage System (1983) (46)
- A new reaction for glycine biosynthesis. (1966) (45)
- Physiological significance of glycine cleavage system in human liver as revealed by the study of a case of hyperglycinemia. (1969) (43)
- A stoichiometric study of heme degradation catalyzed by the reconstituted heme oxygenase system with special consideration of the production of hydrogen peroxide during the reaction. (1983) (43)
- Mechanism of the reversible glycine cleavage reaction in Arthrobacter globiformis. I. Purification and function of protein components required for the reaction. (1974) (43)
- The mitochondrial glycine cleavage system (1982) (42)
- Sequence of the reaction of heme catabolism catalyzed by the microsomal heme oxygenase system (1974) (41)
- Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine. (1969) (41)
- Reaction of the microsomal heme oxygenase with cobaltic protoporphyrin IX, and extremely poor substrate. (1978) (40)
- Regulation of synthesis and intracellular translocation of delta-aminolevulinate synthase by heme and its relation to the heme saturation of tryptophan pyrrolase in rat liver. (1981) (40)
- Degradation of mesoheme and hydroxymesoheme catalyzed by the heme oxygenase system: involvement of hydroxyheme in the sequence of heme catabolism. (1981) (39)
- Identification of the product of heme degradation catalyzed by the heme oxygenase system as biliverdin IX alpha by reversed-phase high-performance liquid chromatography. (1982) (39)
- Reduction of the level of the glycine cleavage system in the rat liver resulting from administration of dipropylacetic acid: an experimental approach to hyperglycinemia. (1979) (38)
- Electron transport system in Ascaris lumbricoides. (1959) (38)
- EFFECT OF INHIBITORS OF NUCLEIC ACID AND PROTEIN SYNTHESES ON THE INDUCED SYNTHESES OF BACTERIOCHLOROPHYLL AND DELTA-AMINOLEVULINIC ACID SYNTHETASE BY RHODOPSEUDOMONAS SPHEROIDES. (1965) (37)
- Occurrence and properties of two types of δ-aminolevulinate synthetase in Rhodopseudomonas spheroides☆ (1970) (37)
- Purification and some properties of delta-aminolevulinate synthase from the rat liver cytosol fraction and immunochemical identity of the cytosolic enzyme and the mitochondrial enzyme. (1980) (36)
- Induction of heme oxygenase in rat liver. Increase of the specific mRNA by treatment with various chemicals and immunological identity of the enzymes in various tissues as well as the induced enzymes. (1983) (36)
- delta-Aminolevulinate synthase isozymes in the liver and erythroid cells of chicken. (1983) (36)
- Specific requirement of NADPH‐cytochrome c reductase for the microsomal heme oxygenase reaction yielding biliverdin IXα (1979) (36)
- Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate. (1969) (34)
- Occurrence of both a-type and o-type cytochromes as the functional terminal oxidases in Rhodopseudomonas spheroides. (1970) (32)
- A new intermediate of heme degradation catalyzed by the heme oxygenase system. (1980) (32)
- Cell‐free synthesis of rat liver δ‐aminolevulinate synthase and possible occurrence of processing of the enzyme protein in the course of its translocation from the cytosol into the mitochondrial matrix (1980) (32)
- Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in rat-liver mitochondria. (1966) (31)
- Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. Effects of administration of glucose, cyclic AMP, and some hormones related to glucose metabolism. (1974) (30)
- Enzyme complex nature of the reversible glycine cleavage system of cock liver mitochondria. (1972) (29)
- ENZYMATIC SYNTHESIS OF δ‐AMINOLEVULINIC ACID * (1958) (28)
- Effects of administration of cobalt chloride and cobalt protoporphyrin on delta-aminolevulinate synthase in rat liver. (1978) (27)
- Cytochromes in the particulate preparation of the Ascaris lumbricoides muscle. (1961) (27)
- ON CYTOCHROME OXIDASE AS THE TERMINAL OXIDASE OF DARK RESPIRATION OF NON-SULFUR PURPLE BACTERIA. (1965) (26)
- An immunochemical study of δ-aminolevulinate synthase and δ-aminolevulinate dehydratase in liver and erythroid cells of rat☆ (1986) (26)
- The enzymic synthesis of δ-aminolevulinic acid (1958) (25)
- Occurrence of a specific and reversible inhibitor of delta-aminolevulinate synthetase in extracts of Rhodopseudomonas spheroides. (1969) (25)
- Glycin metabolism by rat liver mitochondria. I. Synthesis of two molecules of glycine from one molecule each of serine, bicarbonate and ammonia. (1969) (25)
- Differential induction of fraction I and fraction II of delta-aminolevulinate synthetase in Rhodopseudomonas spheroides under various incubation conditions. (1970) (25)
- Studies on the functional relationship between the phosphopyruvate synthesis and the substrate level phosphorylation in guinea-pig liver mitochondria. (1968) (24)
- Heme degradation by the microsomal heme oxygenase system (1980) (24)
- Glycine metabolism by rat liver mitochondria. Isolation and some properties of the protein-bound intermediate of the reversible glycine cleavage reaction. (1974) (24)
- Function and induction of the microsomal heme oxygenase (2004) (23)
- Mechanism of inhibition by hemin of increase of delta-aminolevulinate synthetase in liver mitochondria. (1970) (23)
- Induction of delta-aminolevulinate synthetase in organ culture of chick embryo liver by allylisopropylacetamide and 3,5-dicarbethoxy-1,4-dihydrocollidine. (1974) (23)
- Significance of the glycine cleavage system in glycine and serine catabolism in avian liver. (1971) (23)
- Immunochemical studies of the turnover of delta-aminolevulinate synthase in rat liver mitochondria and the effect of hemin on it. (1980) (22)
- Glycine metabolism by rat liver mitochondria. II. Methylene tetrahydrofolate as the direct on carbon donor in the reaction of glycine synthesis. (1969) (22)
- Difference in molecular sizes of delta-aminolevulinate synthetases in the soluble and mitochondrial fractions of rat liver. (1970) (21)
- Mechanism of allylisopropylacetamide-induced increase of -aminolevulinate synthetase in liver mitochondria. VI. Multiple molecular forms of -aminolevulinate synthetase in the cytosol and mitochondria of induced cock liver. (1972) (21)
- Electron transport system in Fusarium lini. (1959) (20)
- Occurrence and properties of four forms of phosphoenolpyruvate carboxykinase in the chicken liver. (1974) (20)
- Regulation by heme of synthesis and intracellular translocation of δ-aminolevulinate synthase in the liver (1981) (19)
- OXYGEN EQUILIBRIUM OF HEMOGLOBIN M-IWATE. (1964) (19)
- Inhibition studies of photophosphorylation by Rhodospilillum rubrum chromatophores with particular concerns to antimycin-resistant photophosphorylation in the presence of artificial electron carriers. (1966) (18)
- Effect of inhibitors of DNA synthesis on allylisopropylacetamide-induced increases of delta-aminolevulinic acid synthetase and other enzymes in rat liver. (1965) (17)
- Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. 3. Effects of triiodothyronine and hydrocortisone on the induction process. (1968) (17)
- Catabolism of glycine in Rhodopseudomonas spheroides. (1962) (17)
- Synthesis of Bacteriochlorophyll by Rhodopseudomonas Spheroides Under Dark-Aerobic Conditions (1963) (16)
- Glycine synthesis by extracts of acetone powder of rat-liver mitochondria. (1967) (16)
- Effects of hemin on the synthesis and intracellular translocation of delta-aminolevulinate synthase in the liver of rats treated with 3,5-dicarbethoxy-1,4-dihydrocollidine. (1980) (14)
- Enzymic cleavage of malate to glyoxylate and acetyl-coenzyme A. (1963) (14)
- Purification and some properties of two forms of delta-aminolevulinate synthase from rat liver cytosol. (1979) (14)
- Deoxyuridine triphosphate nucleotidohydrolase activity and its correlation with multiplication of erythroid cells in rat spleen. (1987) (14)
- Alpha-ketoglutarate-dependent oxidation of glyoxylic acid catalyzed by enzymes from Rhodopseudomonas spheroides. (1965) (14)
- Cytochrome systems in dark-aerobically grown Rhodopseudomonas spheroides. (1966) (14)
- ON THE REACTIVITY OF HEMOGLOBIN MIWATE. (1964) (14)
- Role of the glycine-cleavage system in glycine and serine metabolism in various organs. (1980) (13)
- Isolation and partial characterization of the components of the reversible glycine cleavage system of rat liver mitochondria. (1972) (13)
- delta-Aminolevulinate synthetases in the liver cytosol fraction and mitochondria of mice treated with allylisopropylacetamide and 3,5-dicarbethoxyl-1,4-dihydrocollidine. (1976) (13)
- Possible participation of cyclic AMP in the regulation of -aminolevulinic acid synthesis in rat liver. (1972) (12)
- Purification and properties of glycine decarboxylase, a component of the glycine cleavage system, from rat liver mitochondria and immunochemical comparison of this enzyme from various sources. (1980) (12)
- ON THE MECHANISM OF THE ACTIVATION OF MOLECULAR OXYGEN BY HEMOGLOBIN (1955) (12)
- Change of metabolic stability of delta-aminolevulinate synthetase in Rhodopseudomonas spheroides cells probably related to changes of intracellular oxidation-reduction state. (1968) (12)
- On the nature of the enzyme which catalyzes a synergistic decarboxylation of alpha-ketoglutarate and glyoxylate. (1971) (11)
- Differential inhibition of induced syntheses of delta-aminolevulinate synthetase and bacteriochlorophyll in dark-aerobically grown Rhodopseudomonas spheroides. (1967) (11)
- On “Anenzymia Catalasea”. a New Type of Constitutional Abnormity: A Biochemical Note on the Physiological Significance of Catalase in Animal Organism (1952) (11)
- α-Ketoglutarate-dependent oxidation of glyoxylic acid in rat-liver mitochondria (1966) (10)
- Heme oxygenase purified to apparent homogeneity from pig spleen microsomes. (1977) (10)
- VERDOHEMOGLOBIN, AN IMMEDIATE PRECURSOR OF BILIVERDIN IN THE MODEL REACTION OF HEMOGLOBIN BREAKDOWN IN VITRO (1955) (10)
- Enzymic cleavage of malate to glyoxylate and acetyl-coenzyme A. (1962) (10)
- Inability of the NADH‐cytochrome b 5 reductase system to initiate heme degradation yielding biliverdin IXα from the oxygenated form of heme · heme oxygenase complex (1980) (10)
- LIGHT STIMULATION OF THE RESPIRATORY ACTIVITY OF RHODOSPIRILLUM RUBRUM CHROMATOPHORES. (1964) (9)
- Induced formation of ribulose 1,5-diphosphate carboxylase in Rhodopseudomonas spheroides with particular concern to its relation with chromatophore formation (1969) (8)
- Sequence of heme decomposition by the coupled oxidation of myoglobin with ascorbic acid. (1975) (8)
- ENZYMIC CLEAVAGE OF MALYTL-COENZYME A INTO ACETYL-COENZYME A AND GLYOXYLIC ACID. (1965) (8)
- COMPETITION OF PYRIDINE AND CYANIDE TO HEME AND HEMATIN (1956) (8)
- Carboxylic acids metabolism and its relation to porphyrin biosynthesis in Rhodopseudomonas spheroides under light-anaerobic conditions. (1961) (8)
- Photo-reversal by monochromatic light of the carbon monoxide-inhibited heme degradation catalyzed by the reconstituted heme oxygenase system. (1981) (8)
- Intracellular site of synthesis of microsomal heme oxygenase in pig spleen. (1980) (8)
- Evidence for the presence of a protein-bound intermediate in the cleavage and the synthesis of glycine. (1970) (8)
- A possible route of acetate oxidation in Rhodopseudomonas spheroides. (1963) (7)
- Reduced level of glycine cleavage system in the liver of hyperglycinemia patients. (1977) (7)
- The enzymic synthesis of delta-aminolevulinic acid. (1958) (7)
- Relation of the extra-sequence of the precursor form of chicken liver delta-aminolevulinate synthase to its quaternary structure and catalytic properties. (1984) (7)
- STUDIES ON THE REACTION PROCESS OF CHOLEGLOBIN FORMATION (1953) (7)
- Change of the relative proportion of various forms of phosphoenolpyruvate carboxykinase in chicken liver possibly associated with enhanced gluconeogenesis (1974) (7)
- Heme catabolism by the reconstituted heme oxygenase system. (1976) (7)
- The mitochondrial glycine cleavage system: differential inhibition by divalent cations of glycine synthesis and glycine decarboxylation in the glycine-CO2 exchange. (1982) (7)
- ON MALYL-COENZYME A SYNTHETASE. (1964) (6)
- Enzymatic synthesis of sigma-aminolevulinic acid. (1958) (6)
- STUDIES ON THE AFFINITY OF HEME TO PROTEINS (1959) (5)
- Deoxyuridine triphosphate nucleotidohydrolase: distribution of the enzyme in various rat tissues. (1988) (5)
- Comparative studies of the effects of cyclic AMP, various hormones and chloramphenicol on the induction of delta-aminolevulinic acid synthetase and tyrosine aminotransferase in the organ-cultured chick embryo liver. (1976) (4)
- Oxygen equilibrium of hemoglobin Hiroshima. (1968) (4)
- The mitochondrial glycine cleavage system: inactivation of glycine decarboxylase as a side reaction of the glycine decarboxylation in the presence of aminomethyl carrier protein. (1982) (4)
- On the nature of three forms of phosphoenolpyruvate carboxykinase occurring in the cytosol of chicken liver. (1980) (4)
- Phosphoenolpyruvate carboxykinase from Rhodopseudomonas spheroides and its possible role in light-stimulation of glucogenesis. (1966) (4)
- Effects of Drugs and Metals on Heme Degradation by the Heme Oxygenase System (1982) (3)
- REACTION OF VERDOHEMOGLOBIN FORMATION IN VITRO, WITH SPECIAL REFERENCE TO ITS QUANTITATIVE TREATMENT (1956) (3)
- STUDIES ON THE INTERACTION BETWEEN PYRIDINE-HEMIN AND HYDROGEN PEROXIDE OR OXYGEN:IV. ON THE FORMATION OF 630-COMPOUND IN THE REACTION SYSTERM OF PYRIDINE-HEMIN-ASCORBIC ACID-HYDROGEN PEROXIDE (1952) (3)
- STUDIES ON THE INTERACTION BETWEEN PYRIDINE-HEMIN AND HYDROGEN PEROXIDE OR OXYGEN:I. SPECTROSCOPIC OBSERVATIONS ON THE PROCESS OF VERDOHEMOCHROME FORMA-TION WITH SPECIAL REFERENCE TO ITS QUANTITATIVE TREATMENT (1951) (3)
- Inhibition of the metabolism of carboxylic acids and amino acids by citramalate and other related compounds in Rhodopseudomonas spheroides. (1968) (2)
- Regulation by illumination of the citric acid cycle activity in Rhodopseudomonas spheroides. (1966) (2)
- An immunochemical study of delta-aminolevulinate synthase and delta-aminolevulinate dehydratase in liver and erythroid cells of rat. (1986) (2)
- Studies on the mechanism of the conversion of cytosol delta-aminolevulinic acid synthase to the mitochondrial enzyme in the liver of the allylisopropylacetamide-treated rat. (1977) (2)
- ON THE DETACHMENT OF IRON FROM PSEUDOHEMOGLOBIN (1954) (2)
- Synthesis and Translocation of Mitochondrial Matrix Enzymes in Higher Animals with Special Reference to δ-Aminolevulinate Synthase (1982) (2)
- Studies on Pheohemin a and Pheohemin b1 (1959) (2)
- Occurrence and properes of two types of delta-aminolevulinate synthetase in Rhodopseudomonas spheroides. (1970) (2)
- STUDIES ON THE INTERACTION BETWEEN PYRIDINEHEMIN AND HYDROGEN PEROXIDE OR OXYGEN (1952) (2)
- Pyruvate metabolism in Rhodopseudomonas spheroides under light-anaerobic conditions. (1967) (2)
- ON THE CYANIDE-COMPOUNDS OF NATIVE HEMOGLOBIN AND MYOGLOBIN (1955) (1)
- ON THE REACTION OF PSEUDOTHEMOGLOBIN FORMATION IN THE PRESENCE OF SODIUM DITHIONITE (1954) (1)
- ON THE REACTION PROCESS OF PSEUDOHEMOGLOBIN FORMATION (1954) (1)
- Comparative study on induction of hepatic delta-aminolevulinate synthetase by different drugs. (1973) (1)
- Disintegration of Hemoglobin in Connection to its Catalytic Function (1953) (0)
- Glycine decarbonic acid reaction (1973) (0)
- Rapid excretion of choleglobin in urine after intravenous administration of hemoglobin to rabbits. (1961) (0)
- Nucleic acids. III. On the organ-specificity of pentosenucleic acids. (1954) (0)
- Proceedings: Induction and intracellular translocation of delta-aminolevulinic acid synthetase in the liver. (1976) (0)
- Alpha-ketoglutarate-dependent oxidation of glyoxylic acid in rat-liver mitochondria. (1966) (0)
- Studies on the conversion of the cytosol delta-aminolevulinate synthetase to the mitochondrial enzyme. (1976) (0)
- DECOMPOSITION OF HEMATIN IN THE REACTION SYSTEM OF DICYANHEMATIN-ASCORBIC ACID-HYDROGEN PEROXIDE (1957) (0)
- STUDIES ON THE INTERACTION BETWEEN PYRIDINE-HEMIN AND HYDROGEN PEROXIDE OR OXYGEN:II. THE FACTORS AFFECTING THE PROCESS OF VERDOHEMOCHROME FORMATION (1952) (0)
- [Mechanism of heme catabolism (author's transl)]. (1979) (0)
- [Physiological pathways of glycine and serine catabolism in vertebrates]. (1972) (0)
- Report on the Discussion of the Session on Biochemical Microbiology II (1973) (0)
- STUDIES ON THE INTERACTION BETWEEN PYRIDINE-HEMIN AND HYDROGEN PEROXIDE OR OXYGEN:III. ON THE DECOMPOSITION OF PYRIDINE-HEMICHROME BY HYDROGEN PEROXIDE (1952) (0)
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