Gunnar O. Klein
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Why Is Gunnar O. Klein Influential?
(Suggest an Edit or Addition)Gunnar O. Klein's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus. (1981) (441)
- An EBV-genome-negative cell line established from an American Burkitt lymphoma; receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection. (1975) (408)
- Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate. (1979) (398)
- Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx. (1974) (354)
- Studies on the Epstein-Barr Virus genome and the EBV-determined nuclear antigen in human malignant disease. (1975) (340)
- Correlation of mutations of the SH2D1A gene and epstein-barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease. (2000) (241)
- Progressive loss of H-2 antigens with concomitant increase of cell-surface antigen(s) determined by Moloney leukemia virus in cultured murine lymphomas. (1973) (239)
- Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: implications for sites of viral latency. (1988) (238)
- DNA of Epstein-Barr virus detected in tissue of Burkitt's lymphoma and nasopharyngeal carcinoma. (1973) (220)
- Quantitative studies on the multiplication of neoplastic cells in vivo. I. Growth curves of the Ehrlich and MC1M ascites tumors. (1953) (179)
- Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice (1980) (178)
- Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines (1987) (170)
- Horizontal transfer of DNA by the uptake of apoptotic bodies. (1999) (159)
- 5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael (1989) (154)
- Documentation of Epstein-Barr virus infection in immunodeficient patients with life-threatening lymphoproliferative diseases by Epstein-Barr virus complementary RNA/DNA and viral DNA/DNA hybridization. (1981) (141)
- Nasopharyngeal carcinoma. X. Presence of Epstein‐Barr genomes in separated epithelial cells of tumours in patients from Singapore, Tunisia and Kenya (1975) (141)
- Documentation of Epstein-Barr virus infection in immunodeficient patients with life-threatening lymphoproliferative diseases by clinical, virological, and immunopathological studies. (1981) (129)
- Appearance of Epstein-Barr virus-associated antigens in infected Raji cells. (1971) (115)
- Genesis of the 14q+ marker in Burkitt's lymphoma. (2009) (110)
- Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle. (1985) (106)
- Immunochemical Characterization of Epstein-Barr Virus-Associated Early and Late Antigens in n-Butyrate-Treated P3HR-1 Cells (1979) (101)
- Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. (1984) (94)
- Four virally determined nuclear antigens are expressed in Epstein-Barr virus-transformed cells. (1986) (92)
- Quantitative studies on the multiplication of neoplastic cells in vivo. IV. Influence of doubled chromosome number on growth rate and final population size. (1957) (88)
- Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody PAb240. (1991) (88)
- An Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA5) partly encoded by the transformation-associated Bam WYH region of EBV DNA: preferential expression in lymphoblastoid cell lines. (1986) (85)
- Phenotypes in chronic B-lymphocytic leukemia probed by monoclonal antibodies and immunoglobulin secretion studies: identification of stages of maturation arrest and the relation to clinical findings. (1983) (78)
- In vitro NK‐activity and in vivo resistance to leukemia: Studies of beige, beige/nude and wild‐type hosts on C57BL background (1980) (73)
- Effect of interferon-alpha 1 from E. coli on some cell functions. (1980) (71)
- Transfer of Epstein-Barr virus receptors to receptor-negative cells permits virus penetration and antigen expression. (1980) (70)
- Host cell phenotype-dependent methylation patterns of Epstein-Barr virus DNA. (1991) (68)
- Serum-mediated inhibition of lymphocyte stimulation by autochthonous human tumors. (1971) (62)
- BamHI E region of the Epstein-Barr virus genome encodes three transformation-associated nuclear proteins. (1988) (62)
- Disease-related differences in antibody patterns against EBV-encoded nuclear antigens EBNA 1, EBNA 2 and EBNA 6. (1993) (62)
- Effect of n-butyrate on cellular and viral DNA synthesis in cells latently infected with Epstein-Barr virus. (1980) (61)
- Reactivity of human lymphocytes against autochthonous and allogeneic normal and tumor cells in vitro. (1967) (60)
- Human monoclonal antibodies to a genus-specific chlamydial antigen, produced by EBV-transformed B cells. (1983) (59)
- Sequence-specific methylation inhibits the activity of the Epstein-Barr virus LMP 1 and BCR2 enhancer-promoter regions. (1994) (57)
- Host cell macromolecular synthesis in cells containing EBV-induced early antigens, studied by combined immunofluorescence and radioautography. (1971) (56)
- EBNA size polymorphism can be used to trace Epstein-Barr virus spread within families (1990) (55)
- Host-cell-phenotype-dependent control of the BCR2/BWR1 promoter complex regulates the expression of Epstein-Barr virus nuclear antigens 2-6. (1992) (54)
- Quantitative studies of antigen expression in cultured murine lymphoma cells. II. Cell-surface antigens in synchronized cultures. (1972) (54)
- B cell phenotype-dependent expression of the Epstein-Barr virus nuclear antigens EBNA-2 to EBNA-6: studies with somatic cell hybrids. (1991) (53)
- Double minute chromosomes are not centromeric regions of the host chromosomes. (2009) (53)
- Phenotypic modulation of chronic lymphocytic leukemia cells by phorbol ester: induction of IgM secretion and changes in the expression of B cell-associated surface antigens. (1984) (52)
- SEROLOGICAL AND MOLECULAR STUDIES OF EPSTEIN‐BARR VIRUS INFECTION IN ALLOGENEIC MARROW GRAFT RECIPIENTS (1990) (47)
- Characterization of the serological response in man to the latent membrane protein and the six nuclear antigens encoded by Epstein-Barr virus. (1988) (46)
- Hybridization of a myeloid leukemia-derived human cell line (K562) with a human Burkitt's lymphoma line (P3HR-1). (1980) (45)
- The Epstein-Barr virus (EBV) in the pathogenesis of posttransplant lymphoma. (1981) (44)
- Induction and biological characterization of the Epstein-Barr virus (EBV) carried by the Jijoye lymphoma line. (1980) (44)
- Antibodies against synthetic peptides react with the second Epstein‐Barr virus‐associated nuclear antigen. (1985) (43)
- Surface marker characterization of EBV target cells in normal blood and tonsil B lymphocyte populations. (1985) (43)
- Quantitative studies on the multiplication of neoplastic cells in vivo. II. Growth curves of three ascites lymphomas. (1954) (40)
- Two large virion envelope glycoproteins mediate Epstein-Barr virus binding to receptor-positive cells (1982) (40)
- Epstein-Barr virus markers in a series of Burkitt's lymphomas from the West Nile District, Uganda. (1983) (40)
- Detection of multiple Epstein‐Barr viral strains in allogeneic bone marrow transplant recipients (1992) (39)
- Activation of the EBV‐cycle and aggregation of human blood lymphocytes by the tumor promoters teleocidin, lyngbyatoxin a, aplysiatoxin and debromoaplysiatoxin (1983) (39)
- The Epstein-Barr virus and human malignancies. (1976) (38)
- Introduction to Epstein-Barr virus and lymphoproliferative diseases in immunodeficient individuals. (1981) (36)
- Cytogenetic studies on an epithelioid cell line derived from nasopharyngeal carcinoma. (2008) (34)
- Tumor-associated specificity of serum-mediated inhibition of lymphocyte stimulation by autochthonous human tumors. (1973) (30)
- Infection of the human T-cell-derived leukemia line Molt-4 by Epstein-Barr virus (EBV): induction of EBV-determined antigens and virus reproduction. (1982) (30)
- Leukocyte migration inhibition studies with Epstein-Barr virus (EBV) determined nuclear antigen (EBNA) in relation to the EBV-carrier status of the donor. (1981) (29)
- Homology of Epstein-Barr virus DNA in nasopharyngeal carcinomas from Kenya, Taiwan, Singapore and Tunisia. (1975) (29)
- Antigenic characterization of heterozygous mouse lymphomas after immunoselection in vivo. (1968) (29)
- Effects of n-butyrate on Epstein-Barr virus-carrying lymphoma lines. (1982) (28)
- Human thymus-lymphoid tissue antigen and its presence in leukaemia and lymphoma. (1970) (28)
- TPA (12-O-tetradecanoyl-phorbol-13-acetate) activation and differentiation of human peripheral B lymphocytes. (1984) (27)
- Tumour-bound immunoglobulins. The in vitro fixation of radioiodine-labelled anti-immunoglobulin reagents by tumour cells. (1974) (27)
- EB Virus-Induced Antigens (1979) (27)
- An EBV genome carrying pre-B cell leukemia in a homosexual man with characteristic karyotype and impaired EBV-specific immunity. (1986) (26)
- Relationship between Epstein-Barr virus-determined complement-fixing antigen and nuclear antigen detected by anticomplement fluorescence. (1974) (25)
- Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells. (1972) (24)
- Epstein-Barr virus-transformed pro-B cells are prone to illegitimate recombination between the switch region of the μ chain gene and other chromosomes (1989) (23)
- Epstein-Barr virus-carrying cells in Hodgkin's disease [editorial] (1992) (23)
- EPSTEIN-BARR-VIRUS-CARRYING LYMPHOMA IN CARDIAC TRANSPLANT RECIPIENT (1982) (23)
- Long-chain neutral glycolipids and gangliosides of murine fibroblast lines and their low- and high-tumourigenic hybrids. (1976) (23)
- Tumour-bound immunoglobulins. The fate of immunoglobulin disappearing from the surface of coated tumour cells. (1974) (23)
- Quantitative studies on the multiplication of neoplastic cells in vivo. III. Metabolic stability of deoxypentose nucleic acid and the use of labeled tumor cells for the measurement of growth curves. (1956) (22)
- Alternative involvement of two cytogenetically distinguishable breakpoints on chromosome 8 in Burkitt's lymphoma associated translocations. (1986) (22)
- Brief Communication: Induction of Epstein-Barr Virus-Associated Nuclear Antigen During In Vitro Transformation of Human Lymphoid Cells (1975) (22)
- Deficiency of Epstein-Barr virus (EBV) receptors on B lymphocytes from certain patients with common varied agammaglobulinemia. (1980) (22)
- Interferon suppresses antigen- and mitogen-induced leukocyte migration inhibition (1980) (20)
- Experiments with fluorescent chromosome staining in Burkitt tumors. (2009) (20)
- Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. I. Isolation, characterization, cell surface markers, and B-cell markers. (1982) (19)
- Incidence and type of tumors induced in C57BL bg/bg mice and +/bg littermates by oral administration of DMBA (1981) (19)
- Tumour-bound immunoglobulins. The in vitro disappearance of immunoglobulin from the surface of coated tumour cells, and some properties of released components. (1974) (19)
- Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy (1980) (19)
- Studies on the mechanism of isoantigenic variant formation in heterozygous mouse tumors. IV. H-2 component analysis of an (A-Sn x A.SW)F1 lymphoma. (1966) (18)
- Epstein-Barr virus carried by Raji cells: a mutant in early functions? (1983) (18)
- Deficiency of malic enzyme: a possible marker for malignancy in lymphoid cells (1981) (17)
- Diverse familial malignant tumors and Epstein-Barr virus. (1981) (17)
- Quantitative studies of antigen expression in cultured murine lymphoma cells. I. Cell-surface antigens in "Asynchronous" cultures. (1972) (16)
- 14q+ marker chromosome in an EBV‐genome‐negative lymph node without signs of malignancy in a patient with EBV‐genome‐positive nasopharyngeal carcinoma (1979) (16)
- The Epstein-Barr virus receptor is distinct from the C3 receptor. (1983) (16)
- Molecular characterization of novel reciprocal translocation t(6;14) in an Epstein-Barr virus-transformed B cell precursor (1987) (16)
- Transformation induced by Epstein-Barr virus and the role of the nuclear antigen. (1980) (15)
- Relationship between Epstein-Barr virus genome number, amount of nuclear antigen, and early antigen inducibility in diploid and tetraploid lymphoma cells of related origin. (1979) (15)
- The detection of Epstein-Barr virus receptors utilizing radiolabelled virus. (1981) (15)
- In vitro differentiation of chronic lymphocytic leukaemia cells with a small pre-B-like phenotype. (1983) (15)
- The association between undifferentiated nasopharyngeal carcinoma and Epstein-Barr virus shown by correlated nucleic acid hybridization and histopathological studies. (1978) (15)
- Receptors for the complement C3d component and the Epstein-Barr virus are quantitatively coexpressed on a series of B-cell lines and their derived somatic cell hybrids. (1982) (14)
- NASOPHARYNGEAL CARCINOMA. EPITHELIAL CELLS OF TUMOURS IN PATIENTS FROM SINGAPORE, TUNISIA AND KENYA X. PRESENCE OF EPSTEIN-BARR GENOMES IN SEPARATED (1975) (14)
- A fraction of Epstein--Barr virus virion DNA is methylated in and around the EcoRI-J fragment. (1982) (13)
- Detection of antigens determined by the Epstein Barr virus (EBV) in human lymphoblastoid cell culture lines by elution of specific radioiodine labeled antibody. (1974) (13)
- Leukocyte migration inhibition demonstrates a human T-cell response to a membrane protein expressed in latent Epstein-Barr virus infection (1986) (13)
- Membranes of EBV-carrying virus nonproducer cells inhibit leukocyte migration of EBV-seropositive but not seronegative donors. (1981) (13)
- Spontaneous and induced patterns of the Epstein-Barr virus (EBV) cycle in a new set of somatic cell hybrids. (1977) (13)
- Fluorescent pattern of apparently normal chromosomes in Burkitt lymphomas. (2009) (11)
- Use of cryopreserved lymphocytes for the indirect leukocyte migration inhibition assay. (1981) (11)
- Intracellular Epstein-Barr virus DNA is methylated in and around the EcoRI-J fragment in both producer and nonproducer cell lines. (1983) (11)
- Epstein-Barr virus receptor expression is correlated to cell cycle phase. (1981) (11)
- Moloney Lymphoma Antibodies from Mice; Localization in Spleens of Moloney Lymphoma Bearing Mice∗ (1969) (11)
- H-2-associated control of natural cytotoxicity and hybrid resistance against RBL-5 (1978) (10)
- Chromosome #14 markers in two Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines of normal origin differ from the Burkitt lymphoma (BL)-associated 14q+ marker. (1981) (10)
- Immunoglobulin gene organization of ultraviolet-illuminated human lymphoblastoid cell lines producing both IgM and IgG. (1984) (9)
- Hybrid resistance against a natural killer (NK) cell-resistant lymphoma (YWA) is mediated by a T cell-dependent mechanism. (1982) (9)
- Viral expression and immunogenicity of CBA mammary carcinomas and their hybrid lines with an L-cell derivative (A9HT). (1979) (9)
- CYCLIC VARIATIONS IN THE H-2 ISOANTIGENIC EXPRESSION OF MOUSE LYMPHOMA CELLS IN VITRO (1969) (9)
- ‘Hybrid resistance’ against parental tumors: One or several genetic patterns? (1978) (9)
- Differential c-myc protein expression in Burkitt's lymphomas and EBV-transformed lymphoblastoid lines. (1991) (8)
- Thymus independence of hybrid resistance against a panel of T‐cell lymphomas of H‐2b origin (1982) (8)
- Proliferation inhibitory effect of human alpha interferon on primary explants of Burkitt lymphoma: inverse relationship to patient survival. (1981) (8)
- Somatic cell hybrid analyses of hematopoietic differentiation (1981) (8)
- The stemline idiogram of the MSWBS tumor of the mouse and the problem of centric fusion. (2009) (8)
- An improved dot immunobinding assay for screening hybridoma supernatants. Non-purified antigen immobilized on nitrocellulose paper discs. (1991) (8)
- Epstein-Barr virus (EBV) antigen-specific leukocyte migration inhibition (LMI) in infectious mononucleosis (IM). I. Kinetics and response to a membrane protein on EBV-transformed cells. (1986) (8)
- Persistence and transfer of Epstein-Barr virus after allogeneic bone marrow transplantation. (1989) (7)
- Epstein-Barr virus-carrying cells in Hodgkin's disease. (1992) (7)
- Somatic cell hybrid analyses of hematopoietic differentiation. (1981) (7)
- Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. II. Epstein-Barr virus induction patterns. (1982) (7)
- Quantitative comparison of Epstein-Barr virus receptor expression on sIgM and sIgG cell lines and B-cell lymphoma biopsies. (1982) (6)
- A microassay for quantitatively detecting the Epstein-Barr virus receptor on single cells utilizing flow cytometry. (1981) (6)
- B-Cell and Epstein-Barr Virus (EBV) Associated Functions in Human Cells and Hybrids (1980) (6)
- Polyploidization of Epstein-Barr virus (EBV)-carrying lymphoma lines decreases the inducibility of EBV-determined early antigen following P3HR-1 virus superinfection or iododeoxyuridine treatment. (1978) (6)
- Quantitation of Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA) by a two-site enzyme immunoassay, in parallel with EBV-DNA. (1986) (6)
- Dynamic alterations in some surface properties of freshly explanted Moloney lymphoma cells. (1975) (5)
- Genetic differences in F1 hybrid resistance against tumours of the same parental strain. I. Tumours of C57Bl/6 origin. (1981) (5)
- NK-ACTIVITY AGAINST YAC-1 IS REGULATED BY TWO H-2 ASSOCIATED GENES (1982) (4)
- Decreased sensitivity of immunoselected and NK-selected YAC lymphoma sublines to hybrid resistance in vivo. (1982) (4)
- Truncated mu chain in a Burkitt lymphoma line (P3HR-1) and its fate in various hemapoietic somatic cell hybrids. (1982) (4)
- Leukocyte migration inhibitory factor production by activated lymphocytes representing immunological memory or virus-receptor interaction: response of T cell subsets to Epstein-Barr virus nuclear antigen, response of B cells to UV inactivated Epstein-Barr virus. (1985) (4)
- Membrane-bound and cellular immunoglobulins in human B-lymphoma lines and derived hybrids. (1981) (4)
- Lymphocyte subpopulations in immunodeficiency disorders: I. Human thymus-lymphoid tissue antigen (1974) (4)
- Some recent trends in studies of human lymphoid cells: B-cells, Epstein-Barr virus, and transformation. (1981) (3)
- Somatic cell hybrids between human lymphoma and human myeloid leukemia cells. I. Induction of resident viral genome transcription and viral antigen formation by IUDR and TPA. (1981) (3)
- Immune resistance of semisyngeneic F1 hybrid mice to lymphoma grafts differs from natural hybrid resistance in its genetic pattern. (1984) (3)
- [Bacteriophage therapy can be the rescue when antibiotics no longer work]. (2009) (3)
- Incidence and type of tumors induced by DMBA carcinogenesis in H‐2 congenic strains on a B10 background (1983) (3)
- Genetic control of in vitro NK reactivity and its relationship to in vivo tumor resistance. (1980) (3)
- Epstein-Barr virus binding to virus-carrying cell lines is enhanced in the presence of C3 and C3d. (1984) (2)
- Epstein-Barr virus (EBV) antigen-specific leukocyte migration inhibition in infectious mononucleosis. II. Kinetics of sensitization against five EBV-encoded nuclear proteins and the latent membrane protein. (1989) (2)
- Nasopharyngeal carcinoma. (1978) (2)
- Cell phenotype-dependent splicing reflecting differential promoter usage for EBNA transcripts in EBV-carrying cells. (2000) (2)
- HYBRID RESISTANCE TO PARENTAL TUMORS: INFLUENCE OF HOST AND TUMOR GENOTYPE AND TUMOR DERIVATION (1980) (2)
- Radioiodine-labeled antibody elution (RIE) for detection of EBV-determined antigens: Competition for specific labeled antibodies using suspended antigens (1974) (2)
- activation anddifferentiation ofhumanperipheral Blymphocytes (1984) (1)
- INCREASE IN INTRA-CELLULAR LEVELS OF CYCLIC AMP INHIBITS TARGET CELL RECOGNITION BY HUMAN NK CELLS (1982) (1)
- Restriction of C-type viral antigen in H-2/Fv-1 syngeneic mouse somatic cell hybrids. (1980) (1)
- Erratum: Host-cell-phenotype-dependent control of the BCR2/BWR1 promoter complex regulates the expression of Epstein-Barr virus nuclear antigens 2-6 (Natl. Proc. Acad. Sci. USA (February 1, 1992) 89:3 (905-909)) (1992) (1)
- Epstein-Barr virus and tumor promoters. (1983) (1)
- The Use of Antibodies against Synthetic Peptides for Studying the EBV Nuclear Antigen (1985) (1)
- Leukocyte migration inhibition detects cross-reacting antigens between cells transformed by Epstein-Barr virus (EBV) and EBV-like simian viruses. (1986) (1)
- Detection of Epstein-Barr virus-determined intracellular antigens in unfixed cells with labeled antibodies. (1974) (1)
- Antigenic studies on mouse lymphomas bearing the T190 translocation chromosome. (1970) (1)
- Genetic control of in vitro NK-activity and in vivo resistance to tumors. (1983) (1)
- Serological analysis of isoantigenic variants from mouse tumors heterozygous at the H-2. (1965) (1)
- of maturation arrest and the relation to clinical findings antibodies and immunoglobulin secretion studies: identification of stages Phenotypes in chronic B-lymphocytic leukemia probed by monoclonal (2011) (0)
- [Leukocyte migration inhibition evoked by Epstein Barr virus antigen. I. Immune response in healthy donors]. (1981) (0)
- 3 EB Virus-Induced Antigens (1979) (0)
- Plenary lecture symposia genetic control of pattern formation (600–630)Partial rescue of drosophila wingless mutant phenotype by the murine homologue, Int-1 (1989) (0)
- Influence of the host's sex on the pattern of tumor induction by injection of polyoma virus in 'nude' thymus deficient mice. Abstr. (1975) (0)
- Effect of stilbamidine on ascites tumor of mice (1950) (0)
- Tumor-associated immunoglobulins: nature of the association. (1972) (0)
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