Gary l. Nelsestuen
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Biology
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(Suggest an Edit or Addition)Gary l. Nelsestuen's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin. (1974) (414)
- Role of gamma-carboxyglutamic acid. An unusual protein transition required for the calcium-dependent binding of prothrombin to phospholipid. (1976) (201)
- Interaction of vitamin K dependent proteins with membranes. (1978) (155)
- Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. (2005) (143)
- Association of protein kinase C with phospholipid vesicles. (1987) (135)
- Pentraxin family of proteins interact specifically with phosphorylcholine and/or phosphorylethanolamine. (1992) (130)
- Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation. (1987) (128)
- Equilibria involved in prothrombin- and blood-clotting factor X-membrane binding. (1977) (114)
- Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site. (1997) (111)
- Properties of membrane-inserted protein kinase C. (1988) (107)
- Interaction of prothrombin and blood-clotting factor X with membranes of varying composition. (1977) (105)
- Protein kinase C interaction with calcium: a phospholipid-dependent process. (1990) (105)
- Role of gamma-carboxyglutamic acid. Cation specificity of prothrombin and factor X-phospholipid binding. (1976) (104)
- Potent inhibition of terminal complement assembly by clusterin: characterization of its impact on C9 polymerization. (1997) (96)
- The purification and properties of an abnormal prothrombin protein produced by dicumarol-treated cows. A comparison to normal prothrombin. (1972) (94)
- Independent association of serum amyloid P component, protein S, and complement C4b with complement C4b-binding protein and subsequent association of the complex with membranes. (1990) (94)
- Importance of phosphatidylethanolamine for association of protein kinase C and other cytoplasmic proteins with membranes. (1992) (90)
- Extensive segregation of acidic phospholipids in membranes induced by protein kinase C and related proteins. (1991) (88)
- Activation and regulation of protein Kinase C enzymes (1991) (88)
- Structure of the prothrombin- and blood clotting factor X-membrane complexes. (1977) (82)
- Vitamin K-dependent proteins. (2000) (79)
- Assembly of protein S and C4b-binding protein on membranes. (1990) (72)
- Differences in the effects of phorbol esters and diacylglycerols on protein kinase C. (1989) (71)
- Constitutive activity of membrane-inserted protein kinase C. (1988) (70)
- Relative quantification: characterization of bias, variability and fold changes in mass spectrometry data from iTRAQ-labeled peptides. (2011) (68)
- Plasma protein profiling: Unique and stable features of individuals (2005) (67)
- High affinity interaction between C4b-binding protein and vitamin K-dependent protein S in the presence of calcium. Suggestion of a third component in blood regulating the interaction. (1990) (66)
- Possible Synergy between Recombinant Factor VIIa and Prothrombin Complex Concentrate in Hemophilia Therapy (2002) (64)
- Protein structural requirements and properties of membrane binding by gamma-carboxyglutamic acid-containing plasma proteins and peptides. (1989) (63)
- The mode of action of vitamin K. Isolation of a peptide containing the vitamin K-dependent portion of prothrombin. (1973) (62)
- Mechanism of protein kinase C inhibition by sphingosine. (1987) (61)
- Binding and activation properties of human factor XII, prekallikrein, and derived peptides with acidic lipid vesicles. (1985) (59)
- Properties of the protein kinase C-phorbol ester interaction. (1989) (57)
- Highly sequential binding of protein kinase C and related proteins to membranes. (1991) (56)
- Association of protein kinase C with phospholipid monolayers: two-stage irreversible binding. (1988) (55)
- Kinetic and hydrodynamic analysis of blood clotting factor V-membrane binding. (1982) (52)
- Stopped-flow studies of myelin basic protein association with phospholipid vesicles and subsequent vesicle aggregation. (1983) (52)
- Proteomic identification of human neutrophil alpha‐defensins in chronic lung allograft rejection (2005) (51)
- Analysis of chronic lung transplant rejection by MALDI‐TOF profiles of bronchoalveolar lavage fluid (2006) (51)
- Properties of asialo and aglycoprothrombin. (1971) (50)
- The rate-determining step of the heparin-catalyzed antithrombin/thrombin reaction is independent of thrombin. (1982) (49)
- Possible basis for the apparent surface selectivity of the contact activation of human blood coagulation factor XII. (1986) (48)
- Phosphorylation of lens intrinsic membrane proteins by protein kinase C. (1986) (48)
- Amino-terminal alanine functions in a calcium-specific process essential for membrane binding by prothrombin fragment 1. (1988) (47)
- Role of substrate in determining the phospholipid specificity of protein kinase C activation. (1987) (46)
- Calcium and membrane-binding properties of monomeric and multimeric annexin II. (1994) (44)
- The mechanism of action of uridine diphosphoglucose dehydrogenase. Uridine diphosphohexodialdoses as intermediates. (1971) (44)
- Calcium and prothrombin-induced lateral phase separation in membranes. (1981) (42)
- The collisional limit: an important consideration for membrane‐associated enzymes and receptors (1988) (42)
- Prothrombin association with phospholipid monolayers. (1983) (42)
- Metal ion interactions with bovine prothrombin and prothrombin fragment 1. Stoichiometry of binding, protein self-association, and conformational change induced by a variety of metal ions. (1981) (40)
- Kinetic and mechanistic analysis of prothrombin-membrane binding by stopped-flow light scattering. (1982) (40)
- Myelin basic protein-enhanced fusion of membranes. (1982) (39)
- Proteins that bind calcium in a phospholipid-dependent manner. (1991) (38)
- Observations on the binding of lanthanides and calcium to vitamin D-dependent chick intestinal calcium-binding protein. Implications regarding calcium-binding protein function. (1987) (38)
- O-glycoside biomarker of apolipoprotein C3: responsiveness to obesity, bariatric surgery, and therapy with metformin, to chronic or severe liver disease and to mortality in severe sepsis and graft vs host disease. (2009) (35)
- Deglycosylated prothrombin fragment 1. Calcium binding, phospholipid interaction, and self-assocation. (1980) (35)
- Interaction of complement proteins C5b-6 and C5b-7 with phospholipid vesicles: effects of phospholipid structural features. (1986) (35)
- Membrane binding properties of blood coagulation Factor V and derived peptides. (1984) (35)
- Amino acid-directed nucleic acid synthesis (1978) (34)
- Interaction of annexin VI with membranes: highly restricted dissipation of clustered phospholipids in membranes containing phosphatidylethanolamine. (1992) (34)
- Predicting decline of kidney function in lupus nephritis using urine biomarkers (2016) (34)
- [3H]diborane reduction of vitamin K-dependent calcium-binding proteins. Identification of a unique amino acid. (1975) (33)
- On the role of γ-carboxyglutamic acid in calcium and phospholipid binding (1975) (32)
- Two-substrate reaction model for the heparin-catalyzed bovine antithrombin/protease reaction. (1983) (32)
- Temporal stability of the urinary proteome after kidney transplant: more sensitive than protein composition? (2009) (32)
- Membrane permeability to macromolecules mediated by the membrane attack complex. (1989) (32)
- Mutagenesis of the γ-Carboxyglutamic Acid Domain of Human Factor VII to Generate Maximum Enhancement of the Membrane Contact Site* (2003) (31)
- Membrane association with multiple calcium ions: vitamin-K-dependent proteins, annexins and pentraxins. (1999) (31)
- Views on methods for monitoring recombinant factor VIIa in inhibitor patients. (2004) (30)
- Prothrombin--membrane interaction. Effects of ionic strength, pH, and temperature. (1980) (29)
- Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: implications for protein--membrane contact. (1996) (29)
- Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: studies related to proline-10. (1997) (28)
- Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII. (1998) (28)
- Association of a protein with membrane vesicles at the collisional limit: studies with blood coagulation factor Va light chain also suggest major differences between small and large unilamellar vesicles. (1987) (28)
- The carbohydrate of bovine prothrombin. Partial structural determination demonstrating the presence of -galactose residues. (1972) (27)
- Direct enthalpy measurements of the calcium-dependent interaction of annexins V and VI with phospholipid vesicles. (1994) (26)
- Reduced outer membrane permeability of Escherichia coli O157:H7: suggested role of modified outer membrane porins and theoretical function in resistance to antimicrobial agents. (2001) (26)
- Protein kinase C and annexins: unusual calcium response elements in the cell. (1993) (26)
- Elevated Function of Blood Clotting Factor VIIa Mutants That Have Enhanced Affinity for Membranes (2001) (25)
- Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. (2015) (24)
- Enhancement of Human Protein C Function by Site-directed Mutagenesis of the γ-Carboxyglutamic Acid Domain* (1998) (24)
- Steady state enzyme velocities that are independent of [enzyme]: an important behavior in many membrane and particle-bound states. (1997) (24)
- The physical significance of Km in the prothrombinase reaction. (1983) (24)
- Isolation and characterization of vitamin K-dependent region of bovine blood clotting factor X. (1975) (23)
- Enhancement of vitamin-K-dependent protein function by modification of the gamma-carboxyglutamic acid domain: studies of protein C and factor VII. (1999) (22)
- Assembly of the membrane attack complex of complement on small unilamellar phospholipid vesicles. (1986) (21)
- A functional polymorphism of apolipoprotein C1 detected by mass spectrometry (2006) (21)
- Heparin influence on the complex of serum amyloid P component and complement C4b-binding protein. (1991) (21)
- Autophosphorylation of protein kinase C may require a high order of protein-phospholipid aggregates. (1992) (20)
- Kinetics of annexin VI, calcium, and phospholipid association and dissociation. (1995) (20)
- Importance of cis-proline 22 in the membrane-binding conformation of bovine prothrombin. (1996) (19)
- The prothrombinase reaction: "mechanism switching" between Michaelis-Menten and non-Michaelis-Menten behaviors. (1996) (19)
- Kinetic properties of enzyme populations in vivo: alkaline phosphatase of the Escherichia coli periplasm. (1992) (19)
- Association of Blood Coagulation Factors V and X with Phospholipid Monolayers (1983) (18)
- Amino acid catalyzed condensation of purines and pyrimidines with 2-deoxyribose. (1979) (18)
- Substrate-specific stimulation of protein kinase C by polyvalent anion. (1987) (18)
- Electron microscopy and hydrodynamic properties of blood clotting factor V and activation fragments of factor V with phospholipid vesicles. (1984) (18)
- Gamma-carboxyglutamic acid: identification and distribution in vitamin K-dependent proteins. (1974) (18)
- Accurate kinetic modeling of alkaline phosphatase in the Escherichia coli periplasm: implications for enzyme properties and substrate diffusion. (1996) (17)
- Vitamin K-dependent plasma proteins. (1984) (17)
- Properties of a Ca2+ binding peptide from prothrombin. (1974) (17)
- Interactions of vitamin K-dependent proteins with calcium ions and phospholipid membranes. (1978) (17)
- Studying multiple protein profiles over time to assess biomarker validity (2006) (17)
- von Willebrand factor. A protein which binds at the cell surface interface between platelets. (1983) (16)
- Membrane lateral phase separation induced by proteins of the prothrombinase complex (1983) (16)
- Association of rat C-reactive protein and other pentraxins with rat lipoproteins containing apolipoproteins E and A1. (1995) (16)
- Mode of action of vitamin K. Calcium binding properties of bovine prothrombin. (1972) (16)
- Response of Factor VIII and IX-Deficient Blood to Wild Type and High Membrane Affinity Mutant Factor VIIa in an In Vitro Whole Blood Clotting Assay: Possible Correlation to Clinical Outcome (2002) (15)
- Steady-state enzyme kinetics in the Escherichia coli periplasm: a model of a whole cell biocatalyst. (1999) (15)
- γ-carboxyglutamic acid distribution (1976) (15)
- Kinetic analysis of various heparin fractions and heparin substitutes in the thrombin inhibition reaction. (1985) (14)
- Reaction of nitric oxide and its derivatives with sulfites: a possible role in sulfite toxicity. (1995) (14)
- Efficacy of soluble phospholipids in the prothrombinase reaction. (2005) (14)
- Terbium probe of calcium-binding sites on the prothrombin-membrane complex. (1986) (14)
- Correlation of a T45S variant of apolipoprotein C1 with elevated BMI in persons of American Indian and Mexican ancestries (2007) (14)
- Sitagliptin Results in a Decrease of Truncated Apolipoprotein C1 (2015) (13)
- Origin of life: Consideration of alternatives to proteins and nucleic acids (1980) (13)
- Direct enthalpy measurements of factor X and prothrombin association with small and large unilamellar vesicles. (1994) (13)
- Peptides in Bronchoalveolar Lavage in Chronic Obstructive Pulmonary Disease (2016) (13)
- Potential biomarkers of an exaggerated response to endotoxemia (2007) (12)
- Fluid-phase assembly of the membrane attack complex of complement. (1986) (12)
- Amino acid-directed nucleic acid synthesis. A possible mechanism in the origin of life. (1978) (12)
- Relationship of turbidity to the stages of platelet aggregation. (1986) (11)
- Effects of temperature and pH on prothrombin fragment 1 conformation as determined by nuclear magnetic resonance. (1981) (11)
- Top‐down proteomic analysis by MALDI‐TOF profiling: Concentration‐independent biomarkers (2008) (10)
- Glycoproteins and glycosylation: apolipoprotein c3 glycoforms by top-down maldi-tof mass spectrometry. (2012) (10)
- Dissociation of peripheral protein‐membrane complexes by high pressure (1992) (10)
- Association of α-phosphatidylinositol-specific phospholipase C with phospholipid vesicles (1992) (9)
- Ionic properties of membrane association by vitamin K-dependent proteins: the case for univalency. (1997) (9)
- Uridine diphosphoglucose 4-epimerase: kinetic isotope effect. (1970) (9)
- Carbohydrate-linked asparagine-101 of prothrombin contains a metal ion protected acetylation site. Acetylation of this site causes loss of metal ion induced protein fluorescence change. (1988) (9)
- Molecular weight analysis of antithrombin III-heparin and antithrombin III-thrombin-heparin complexes. (1986) (9)
- Urinary Peptide Patterns in Native Kidneys and Kidney Allografts (2009) (8)
- Polypeptides and protein structure (1982) (8)
- Tb3+ binding to bovine prothrombin and bovine prothrombin fragment 1. (1985) (8)
- Large enhancement of functional activity of active site-inhibited factor VIIa due to protein dimerization: insights into mechanism of assembly/disassembly from tissue factor. (2005) (7)
- Significance of reduced dimensionality in reaction kinetics: impact of multi-site particles. (1999) (7)
- 113Cd NMR study of bovine prothrombin fragment 1 and factor X. (1986) (7)
- A simple, economical synthesis of uridine diphospho-N-acetylgalactosamine-6-3H. (1971) (6)
- Dissociation of serum amyloid P from C4b-binding protein and other sites by lactic acid: potential role of lactic acid in the regulation of pentraxin function. (1995) (6)
- Phosphorylation of troponin I by protein kinase C: mechanism of inhibition by calmodulin and troponin C. (1987) (6)
- Prothrombin fragment 1-membrane interactions: a calcium-43 NMR study. (1984) (5)
- Elevated Peptides in Lung Lavage Fluid Associated with Bronchiolitis Obliterans Syndrome (2014) (4)
- Unusual benefits of macromolecular shielding by polyethylene glycol for reactions at the diffusional limit: the case of factor VIIai and tissue factor. (2002) (4)
- Crystallization and preliminary X-ray data of proteins derived from prothrombin. (1980) (3)
- Chemical modification of prothrombin fragment 1: documentation of sequential, two-stage loss of protein function. (1988) (3)
- Comparison of the kinetic behavior of human and bovine proteins in the heparin-catalyzed antithrombin III/thrombin reaction. (1987) (3)
- Irreversible degradation of histidine-96 of prothrombin fragment 1 during protein acetylation: another unusually reactive site in the kringle. (1988) (3)
- Bovine prothrombin does not contain α-d-galactopyranosyl groups (1980) (3)
- Calcium effects on prothrombin and its reaction with bifunctional alkylating reagents. (1983) (3)
- A partial remedy for the non-relationship between reversibility of a reaction in the cell and the value of ΔG°′ (1989) (2)
- Proteomic Analysis of Gray Platelet Syndrome by iTRAQ Labelling and Mass Spectroscopy: A Potential New Diagnostic Strategy for Platelet Disorders. (2005) (2)
- Prothrombin's calcium ion binding site. Carbon-13 nuclear magnetic resonance studies. (1975) (1)
- Identification and Validation of Proteinase 3 and Latent Matrix-Metalloproteinase 9 as Potential Biomarkers for Chronic Lung Transplant Rejection (2007) (1)
- Influence of sulfites on the action of nitric oxide and s-nitrosoglutathione in vitro and in vivo (1996) (1)
- Alveolar Epithelial Cell Proteome in Hyperoxic Lung Injury. (2009) (1)
- Vitamin K: Blood Coagulation and Use in Therapy (2004) (1)
- Plasma Proteome Profiling: Widespread Oxidative Changes in Endotoxemia Correlate with Intravascular Tissue Factor Response. (2004) (1)
- On the role of gamma-carboxyglutamic acid in calcium and phospholipid binding. (1975) (1)
- γ-Carboxyglutamic acid: Assay methods (1984) (1)
- Association of alpha-phosphatidylinositol-specific phospholipase C with phospholipid vesicles. (1992) (0)
- Chapter 2 How enzymes work (1995) (0)
- Erratum: Amino acid catalyzed condensation of purines and pyrimidines with 2-deoxyribose (Biochemistry (1979) 18 13 (2843-2846)) (1979) (0)
- How Life Began (1980) (0)
- Calcium involvement in the protein-membrane systems of blood coagulation (1983) (0)
- Dependent polypeptides Modified vitamin K (1998) (0)
- gamma-Carboxyglutamic acid distribution. (1976) (0)
- A brief introduction to reaction pathways (1980) (0)
- Gamma-carboxyglutamic acid: assay methods. (1984) (0)
- Characterization of outer membrane porins expressed by E. coli O157:H7: Observed lowered permeability characteristics and correlation to potential drug targets (2002) (0)
- Binding and autoactivation of human Factor XII with sulfatide vesicles (1984) (0)
- Binding of human factor XII (XII) and prekallikrein to sulfatides (S) and the relationship to XII activation (1985) (0)
- WITHDRAWN: Extraordinary apolipoprotein oxidation in chronic hepatitis C and liver cirrhosis. (2007) (0)
- Authors' reply (1989) (0)
- Association of human and bovine Von Willebrand factors with human platelets (1984) (0)
- Corrections - Amino Acid Catalyzed Condensation of Purines and Pyrimidines with 2-Deoxyribose (1979) (0)
- Erratum: Structural determinants of the factor IX molecule mediating interaction with the endothelial cell binding site are distinct from those involved in phospholipid binding (The Journal of Biological Chemistry, Vol. 264 (1989) 20283-20287) (1990) (0)
- Extraordinary apolipoprotein oxidation in chronic and liver (2007) (0)
- Review of Lawrence J. Berline, Thrombin Structure and Function. (1993) (0)
- Bovine prothrombin does not contain alpha-D-galactopyranosyl groups. (1980) (0)
- Substrate determines the cofactor requirements of protein kinase c (1987) (0)
- Molecular weight studies of antithrombin III-heparin-thrombin complexes (1985) (0)
- Dynamic aspects of factor V-derived peptide-membrane binding (1984) (0)
- Reconstitution of functional von Willebrand factor receptor in phospholipid vesicles (1984) (0)
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What Schools Are Affiliated With Gary l. Nelsestuen?
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