Gary M. Bokoch
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Biology
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(Suggest an Edit or Addition)Gary M. Bokoch's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biology of the p21-activated kinases. (2003) (1119)
- Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics (1999) (1096)
- Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases* (1999) (823)
- Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*) (1995) (794)
- Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. (1997) (740)
- Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells (1997) (722)
- Localized Rac activation dynamics visualized in living cells. (2000) (711)
- Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets (1995) (683)
- The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells (1994) (676)
- Activation of Rac and Cdc42 by integrins mediates cell spreading. (1998) (673)
- Inhibition of myosin light chain kinase by p21-activated kinase. (1999) (653)
- GDIs: central regulatory molecules in Rho GTPase activation. (2005) (650)
- Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. (1991) (641)
- Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton (2002) (587)
- rac, a novel ras-related family of proteins that are botulinum toxin substrates. (1989) (548)
- Chemoattractant signaling and leukocyte activation. (1995) (545)
- Identification of the predominant substrate for ADP-ribosylation by islet activating protein. (1983) (461)
- Requirements for Both Rac1 and Cdc42 in Membrane Ruffling and Phagocytosis in Leukocytes (1997) (452)
- Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors. (1995) (423)
- Regulation of receptor-mediated endocytosis by Rho and Rac (1996) (421)
- NADPH oxidases: not just for leukocytes anymore! (2003) (394)
- Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. (1984) (374)
- p21-Activated Kinase 1 Phosphorylates the Death Agonist Bad and Protects Cells from Apoptosis (2000) (373)
- Current molecular models for NADPH oxidase regulation by Rac GTPase. (2002) (349)
- Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin (1984) (343)
- Cofilin phosphatases and regulation of actin dynamics. (2006) (343)
- Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)* (1996) (339)
- Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics (2005) (327)
- Membrane targeting of p21‐activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells (1998) (320)
- Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components. (1993) (318)
- A Role for P21-Activated Kinase in Endothelial Cell Migration (1999) (311)
- GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA. (2008) (307)
- Molecular basis for Rac2 regulation of phagocyte NADPH oxidase (2001) (305)
- Regulation of innate immunity by Rho GTPases. (2005) (305)
- Regulation of macropinocytosis by p21-activated kinase-1. (2000) (303)
- The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein. (1984) (303)
- The cytotoxic cell protease granzyme B initiates apoptosis in a cell‐free system by proteolytic processing and activation of the ICE/CED‐3 family protease, CPP32, via a novel two‐step mechanism. (1996) (294)
- Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558. (1994) (273)
- p21-activated protein kinase: a crucial component of morphological signaling? (1999) (271)
- Adenovirus Endocytosis Requires Actin Cytoskeleton Reorganization Mediated by Rho Family GTPases (1998) (267)
- The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition. (1984) (264)
- Regulation of leading edge microtubule and actin dynamics downstream of Rac1 (2003) (262)
- Signal transduction and cytoskeletal activation in the neutrophil. (1987) (262)
- Identification of a Central Phosphorylation Site in p21-activated Kinase Regulating Autoinhibition and Kinase Activity* (1999) (259)
- Rho Family Proteins Modulate Rapid Apoptosis Induced by Cytotoxic T Lymphocytes and Fas* (2000) (251)
- Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. (1994) (250)
- Localization of p21-Activated Kinase 1 (PAK1) to Pinocytic Vesicles and Cortical Actin Structures in Stimulated Cells (1997) (249)
- Regulation of Microtubule Destabilizing Activity of Op18/Stathmin Downstream of Rac1* (2004) (247)
- Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase. (2004) (243)
- p21-activated Kinase (PAK1) Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Kinase-1 (PDK1)* (2000) (242)
- 14-3-3 Regulates Actin Dynamics by Stabilizing Phosphorylated Cofilin (2002) (235)
- Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells. (1996) (232)
- GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. (2007) (229)
- D4-GDI, a Substrate of CPP32, Is Proteolyzed during Fas-induced Apoptosis (*) (1996) (225)
- A GTPase-independent Mechanism of p21-activated Kinase Activation (1998) (220)
- PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility (2008) (219)
- The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins. (2000) (218)
- Emerging concepts in the Ras superfamily of GTP‐binding proteins (1993) (210)
- The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes. (1984) (209)
- Biologically active lipids are regulators of Rac.GDI complexation. (1993) (209)
- Increased neutrophil respiratory burst in bcr-null mutants (1995) (204)
- Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. (2007) (204)
- G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling Complexes (*) (1995) (201)
- The p21Rac/Cdc42-activated kinases (PAKs). (1998) (195)
- Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. (1996) (194)
- Spatial and Temporal Analysis of Rac Activation during Live Neutrophil Chemotaxis (2002) (181)
- A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. (2010) (178)
- p21-activated Kinase 1 Phosphorylates and Regulates 14-3-3 Binding to GEF-H1, a Microtubule-localized Rho Exchange Factor* (2004) (174)
- Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration (2003) (171)
- Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods. (2002) (169)
- Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. (1992) (169)
- Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. (1995) (168)
- Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis? (2008) (167)
- Mechanism of human dermal fibroblast migration driven by type I collagen and platelet-derived growth factor-BB. (2003) (164)
- Reactive oxygen species regulate a slingshot-cofilin activation pathway. (2009) (163)
- Regulation of Actin Polymerization in Cell-free Systems by GTPγS and Cdc42 (1997) (163)
- Activation of Rac1 and the p38 Mitogen-activated Protein Kinase Pathway in Response to All-trans-retinoic Acid* (2001) (162)
- Dynamics of cytoskeletal proteins during Fcgamma receptor-mediated phagocytosis in macrophages. (2002) (157)
- GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction. (2006) (157)
- Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling. (2006) (153)
- Regulation of the human neutrophil NADPH oxidase by the Rac GTP-binding proteins. (1994) (150)
- Epoxycyclopentenone-Containing Oxidized Phospholipids Restore Endothelial Barrier Function via Cdc42 and Rac (2004) (149)
- Regulation of the phagocyte NADPH oxidase by Rac GTPase. (2006) (148)
- Phosphorylation of p85 βPIX, a Rac/Cdc42-specific Guanine Nucleotide Exchange Factor, via the Ras/ERK/PAK2 Pathway Is Required for Basic Fibroblast Growth Factor-induced Neurite Outgrowth* (2002) (144)
- Epac/Rap and PKA are novel mechanisms of ANP‐induced Rac‐mediated pulmonary endothelial barrier protection (2008) (141)
- β-Arrestin-dependent Regulation of the Cofilin Pathway Downstream of Protease-activated Receptor-2* (2007) (137)
- P-Rex1 Is a Primary Rac2 Guanine Nucleotide Exchange Factor in Mouse Neutrophils (2005) (135)
- Regulation of the phagocyte respiratory burst by small GTP-binding proteins. (1995) (133)
- The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1. (2008) (130)
- A Tyrosine Kinase Signaling Pathway Accounts for the Majority of Phosphatidylinositol 3,4,5-Trisphosphate Formation in Chemoattractant-stimulated Human Neutrophils* (1996) (129)
- GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. (1993) (126)
- Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge. (2009) (126)
- Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils. (1991) (122)
- Effect of various lipoxygenase metabolites of arachidonic acid on degranulation of polymorphonuclear leukocytes. (1981) (121)
- αPix Stimulates p21-activated Kinase Activity through Exchange Factor-dependent and -independent Mechanisms* (1999) (119)
- p21-activated Kinase 1 (PAK1) Interacts with the Grb2 Adapter Protein to Couple to Growth Factor Signaling* (2003) (119)
- Mastoparan interacts with the carboxyl terminus of the alpha subunit of Gi. (1990) (119)
- Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase. (1993) (116)
- Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A. (1991) (112)
- Localization of p21‐activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils (1999) (109)
- Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis. (2006) (108)
- Multiple GTP-binding proteins regulate vesicular transport from the ER to Golgi membranes (1992) (106)
- Sphingosine Is a Novel Activator of 3-Phosphoinositide-dependent Kinase 1* (2000) (106)
- Human myosin-IXb is a mechanochemically active motor and a GAP for rho. (1998) (106)
- The Rac Target NADPH Oxidase p67 Interacts Preferentially with Rac2 Rather Than Rac1 (*) (1996) (106)
- Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins. (1993) (104)
- Novel p47phox-Related Organizers Regulate Localized NADPH Oxidase 1 (Nox1) Activity (2009) (102)
- Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors (1995) (99)
- p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells. (1998) (99)
- Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis. (1998) (98)
- Regulation of NADPH oxidase activity by Rac GTPase activating protein(s). (1993) (98)
- Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes. (1994) (97)
- The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes. (1997) (95)
- Regulation of Nox1 Activity via Protein Kinase A-mediated Phosphorylation of NoxA1 and 14-3-3 Binding* (2007) (94)
- Lateral segregation of neutrophil chemotactic receptors into actin- and fodrin-rich plasma membrane microdomains depleted in guanyl nucleotide regulatory proteins (1988) (93)
- Guanine Nucleotide Exchange Factors Regulate Specificity of Downstream Signaling from Rac and Cdc42* (1998) (93)
- Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation. (2008) (93)
- Stimulation of arachidonic acid metabolism in the polymorphonuclear leukocyte by an N-formylated peptide. Comparison with ionophore A23187. (1980) (93)
- Mechanism of p21-activated Kinase 6-mediated Inhibition of Androgen Receptor Signaling* (2004) (92)
- Alpha 2-adrenergic receptor stimulation mobilizes intracellular Ca2+ in human erythroleukemia cells. (1989) (92)
- c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells (2010) (92)
- Antagonistic Cross-talk between Rac and Cdc42 GTPases Regulates Generation of Reactive Oxygen Species* (2004) (90)
- The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein (1991) (89)
- Bacillus anthracis Toxins Inhibit Human Neutrophil NADPH Oxidase Activity1 (2006) (89)
- Regulation of hypoxic neuronal death signaling by neuroglobin (2008) (87)
- Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac. (1994) (87)
- Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration (2011) (87)
- Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes. (1981) (86)
- Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells. (1992) (84)
- Inhibition of the neutrophil oxidative response to a chemotactic peptide by inhibitors of arachidonic acid oxygenation. (1979) (79)
- Agents That Inhibit Rho, Rac, and Cdc42 Do Not Block Formation of Actin Pedestals in HeLa Cells Infected with Enteropathogenic Escherichia coli (1998) (79)
- Domains of the human neutrophil N-formyl peptide receptor involved in G protein coupling. Mapping with receptor-derived peptides. (1994) (79)
- The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. (2003) (78)
- Role of the Rho GTPase in bradykinin-stimulated nuclear factor-kappaB activation and IL-1beta gene expression in cultured human epithelial cells. (1998) (76)
- Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions. (2004) (74)
- p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. (1997) (73)
- Identification of a Conserved Rac-binding Site on NADPH Oxidases Supports a Direct GTPase Regulatory Mechanism* (2008) (71)
- Subcellular localization and quantitation of the major neutrophil pertussis toxin substrate, Gn (1988) (69)
- Regulation of ligand-receptor dynamics by guanine nucleotides. Real-time analysis of interconverting states for the neutrophil formyl peptide receptor. (1987) (68)
- Isolation and Characterization of Cytoplasmic Cofilin-Actin Rods* (2009) (67)
- Human Neutrophils Coordinate Chemotaxis by Differential Activation of Rac1 and Rac21 (2009) (65)
- Regulation of chemoattractant receptor interaction with transducing proteins by organizational control in the plasma membrane of human neutrophils (1989) (64)
- The Renaturable 69- and 63-kDa Protein Kinases That Undergo Rapid Activation in Chemoattractant-stimulated Guinea Pig Neutrophils Are p21-Activated Kinases* (1996) (63)
- Mechanisms of guanine nucleotide-mediated regulation of adenylate cyclase activity. (1984) (63)
- Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain. (1993) (63)
- The integrin β tail is required and sufficient to regulate adhesion signaling to Rac1 (2002) (63)
- Interferon-γ Listericidal Action Is Mediated by Novel Rab5a Functions at the Phagosomal Environment* (2001) (63)
- The microtubule-associated Rho activating factor GEF-H1 interacts with exocyst complex to regulate vesicle traffic. (2012) (62)
- Stimulus-dependent Regulation of the Phagocyte NADPH Oxidase by a VAV1, Rac1, and PAK1 Signaling Axis* (2008) (62)
- Signaling requirements for translocation of P‐Rex1, a key Rac2 exchange factor involved in chemoattractant‐stimulated human neutrophil function (2007) (62)
- Emerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases. (2009) (62)
- Ligand-receptor dynamics and signal amplification in the neutrophil. (1987) (61)
- Role of the mevalonate pathway of isoprenoid synthesis in IL‐8 generation by activated monocytic cells (1994) (60)
- Beta‐arrestin‐dependent regulation of the cofilin pathway downstream of Protease‐activated receptor‐2 (2007) (58)
- Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction? (1998) (57)
- Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI. (2001) (57)
- Neutrophil Methods and Protocols (2007) (57)
- A novel cardioprotective role of RhoA: new signaling mechanism for adenosine. (2001) (55)
- Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development (2006) (54)
- FGD2, a CDC42-specific Exchange Factor Expressed by Antigen-presenting Cells, Localizes to Early Endosomes and Active Membrane Ruffles* (2008) (52)
- Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. (2008) (51)
- Control of neutrophil pseudopods by fluid shear: role of Rho family GTPases. (2005) (51)
- SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism. (1994) (50)
- Purification and characterization of the 22,000-dalton GTP-binding protein substrate for ADP-ribosylation by botulinum toxin, G22K. (1988) (49)
- Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation. (2011) (49)
- Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor. (1996) (48)
- Identification of novel GTP‐binding proteins in the human neutrophil (1988) (48)
- The presence of free G protein beta/gamma subunits in human neutrophils results in suppression of adenylate cyclase activity. (1987) (48)
- Adhesion-related Kinase Repression of Gonadotropin-releasing Hormone Gene Expression Requires Rac Activation of the Extracellular Signal-regulated Kinase Pathway* (2002) (47)
- Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins (1990) (45)
- Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1. (2000) (43)
- alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms. (1999) (43)
- Stimulus-induced dissociation of alpha subunits of heterotrimeric GTP-binding proteins from the cytoskeleton of human neutrophils. (1993) (42)
- Rho GTPases and the control of the oxidative burst in polymorphonuclear leukocytes. (2005) (41)
- Reconstitution of a physical complex between the N-formyl chemotactic peptide receptor and G protein. Inhibition by pertussis toxin-catalyzed ADP ribosylation. (1992) (41)
- The role of small GTP-binding proteins in leukocyte function. (1994) (41)
- Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels. (1991) (40)
- Faculty Opinions recommendation of A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. (2008) (39)
- Rho GTPases and leukocyte cytoskeletal regulation (1997) (39)
- Guanine nucleotide binding properties of rap1 purified from human neutrophils. (1990) (39)
- ArgBP2γ Interacts with Akt and p21-activated Kinase-1 and Promotes Cell Survival* (2005) (37)
- Potential drug targets: small GTPases that regulate leukocyte function. (1999) (37)
- Identification of rho as a substrate for botulinum toxin C3‐catalyzed ADP‐ribosylation (1989) (35)
- Interplay between Ras‐related and heterotrimeric GTP binding proteins: lifestyles of the BIG and little 1 (1996) (35)
- Expression and translocation of Rac2 in eosinophils during superoxide generation (1999) (34)
- PyK 2 and FAK connections to p 190 Rho guanine nucleotide exchange factor regulate RhoA activity , focal adhesion formation , and cell motility (2008) (33)
- Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator. (1997) (33)
- Inhibition of MG‐63 cell proliferation and PDGF‐stimulated cellular processes by inhibitors of phosphatidylinositol 3‐kinase (1997) (33)
- Facilitation of Ca(2+)-dependent exocytosis by Rac1-GTPase in bovine chromaffin cells. (2003) (32)
- Direct or C5a-induced Activation of Heterotrimeric Gi2 Proteins in Human Neutrophils Is Associated with Interaction between Formyl Peptide Receptors and the Cytoskeleton* (1996) (31)
- Critical Role of Proline-Rich Tyrosine Kinase 2 in Reversion of the Adhesion-Mediated Suppression of Reactive Oxygen Species Generation by Human Neutrophils1 (2005) (26)
- Chapter 4 Signal Transduction by GTP Binding Proteins during Leukocyte Activation: Phagocytic Cells (1990) (25)
- Differential amplification of antagonistic receptor pathways in neutrophils. (1991) (24)
- Affinity-based assay of Rho guanosine triphosphatase activation. (2006) (24)
- Isoproterenol-induced subcellular redistribution of G-protein beta subunits in S49 lymphoma cells demonstrated by a novel competitive ELISA. (1995) (23)
- A Role for p 21-Activated Kinase in Endothelial Cell Migration (1999) (23)
- Rac and Rap GTPase activation assays. (2007) (23)
- Regulation of phagocyte function by low molecular weight GTP‐binding proteins (1993) (21)
- Phosphorylation of RhoGDI by p21-activated kinase 1. (2006) (20)
- The Rap1A protein enhances protein kinase C activity in vitro. (1993) (19)
- Ras-related GTP-binding proteins and leukocyte signal transduction. (1994) (18)
- Contribution of guanine exchange factor H1 in phorbol ester-induced apoptosis (2006) (18)
- Modulation of Myosin Light-Chain Phosphorylation by p21-Activated Kinase 1 in Escherichia coli Invasion of Human Brain Microvascular Endothelial Cells (2003) (17)
- Reconstitution and characterization of the human neutrophil N-formyl peptide receptor and GTP binding proteins in phospholipid vesicles. (1989) (17)
- A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation (2013) (16)
- p210Bcr−Abl desensitizes Cdc42 GTPase signaling for SDF-1α-directed migration in chronic myeloid leukemia cells (2009) (16)
- PAK'n it in: identification of a selective PAK inhibitor. (2008) (15)
- Anthrax Edema Toxin Inhibits Nox1-Mediated Formation of Reactive Oxygen Species by Colon Epithelial Cells (2008) (13)
- Optimization and Characterization of an Inhibitor for NADPH Oxidase 1 (NOX-1) (2011) (13)
- GTP binding proteins and signal transduction in the human neutrophil. (1990) (12)
- Inactivation of Rho GTPases by Statins Attenuates Anthrax Lethal Toxin Activity (2008) (11)
- Microbial killing: hold the bleach and pass the salt! (2002) (11)
- The Rac1/p38 Map kinase pathway is required for IFNα-dependent transcriptional activation but not serine phosphorylation of Stat- proteins (2000) (10)
- Regulation of cell function by Rho GTPases. (2001) (10)
- Neutrophil methods and protocols. Preface. (2007) (10)
- Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI. (2001) (9)
- Probe Report for NOX1 Inhibitors (2010) (9)
- ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival. (2016) (9)
- Mechanisms of human neutrophil oxidant production after severe injury. (2001) (8)
- Supplemental Data GEF-H 1 Modulates Localized RhoA Activation during Cytokinesis under the Control of Mitotic Kinases (2007) (7)
- Measurement of Rac translocation from cytosol to membranes in activated neutrophils. (1995) (6)
- In vivo activity of wild-type and mutant PAKs. (2000) (6)
- Guanine nucleotide regulatory proteins as transducers of receptor-stimulated neutrophil activation. (1987) (5)
- Transduction of proteins into intact neutrophils. (2007) (5)
- Activity of an intracellular lymphocyte stimulator is independent of G-protein interactions, [Ca2+]i elevation, phosphoinositide hydrolysis, and protein kinase C translocation. (1990) (5)
- NADPH Oxidases in Innate Immunity (2009) (5)
- Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton. (1996) (4)
- G-proteins and the association of ligand/receptor complexes with the cytoskeleton in human neutrophils. (1991) (4)
- movements in human neutrophils by tyrosine kinase inhibitors (1995) (4)
- The Biology of Rap (1993) (3)
- Structure and Function of GTP-Binding Proteins in Neutrophil Signal Transduction (1992) (3)
- Role of p‐21‐activated kinases in cell survival and apoptotic pathways (2001) (2)
- Peptide inhibitors MAP the way towards fighting anthrax pathogenesis. (2006) (2)
- CHAPTER 238 – Regulation of the NADPH Oxidase by Rac GTPase (2003) (2)
- Structure-activity Relationships in Flexible Protein Domains : Regulation of rho GTPases by RhoGDI and D 4 GDI (2000) (2)
- as-Adrenergic Receptor Stimulation Mobilizes Intracellular Cas + in Human Erythroleukemia Cells (2001) (2)
- Role of the Rho GTPase in Bradykinin-Stimulated Nuclear Factor-κB Activation and IL-1β Gene Expression in Cultured Human Epithelial Cells (1998) (1)
- Stimulation of Arachidonic Acid Metabolism in the Leukocyte by an N-Formylated Peptide (2001) (1)
- Critical Role of Proline-Rich Tyrosine Kinase (2005) (1)
- Purification of Rac2 from human neutrophils. (1995) (1)
- Comprar Neutrophil Methods and Protocols | Quinn, Mark T. | 9781588297884 | Springer (2007) (1)
- [4] Purification of Rac2 from human neutrophils (1995) (1)
- RhoGDIs in Cancer (2010) (0)
- Contents Vol. 1, 2009 (2009) (0)
- Neutrophil NADPH Oxidase Activity Toxins Inhibit Human Bacillus anthracis (2006) (0)
- Faculty Opinions recommendation of A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. (2007) (0)
- Subject Index Vol. 1, 2009 (2009) (0)
- Table 5, NIMH’s Psychoactive Drug Screening Program results for compound 1 (2011) (0)
- Contributors to Volume 345 (2002) (0)
- Table 3, Selectivity of parent hit and probe compounds compared to that of chlorpromazine (2011) (0)
- Regulation of NADPH Oxidases by Rac GTPase (2010) (0)
- A role for actin in receptor‐mediated endocytosis in mammalian cells (1998) (0)
- Figure 6, Compound 1 (ML171) treatment significantly blocks invadopodia formation in DLD1 cells (2011) (0)
- Faculty Opinions recommendation of Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites. (2009) (0)
- Figure 4, Synthetic schemes for probe compound 1 (2011) (0)
- Chronophin and Slingshot Cofilin Phosphatases in Cytoskeletal Regulation (2010) (0)
- Table 2, Compounds submitted to the MLSMR (2011) (0)
- Figure 3, Stability of Probe ML171 in PBS (2011) (0)
- The structure of the resting and activated platelet cytoskeleton (1998) (0)
- Table 4, SAR Table of Phenothiazines (2011) (0)
- Figure 2, LRMS of probe ML178 (2011) (0)
- activation during chemotaxis Rac1 links leading edge and uropod events through Rho and myosin (2013) (0)
- Figure 5, Flow chart of HTS screening for NOX1 inhibitors (2011) (0)
- by Differential Activation of Rac1 and Rac2 Human Neutrophils Coordinate Chemotaxis (2009) (0)
- Faculty Opinions recommendation of Redox modifier genes in amyotrophic lateral sclerosis in mice. (2007) (0)
- Figure 7, Treatment with compound 1 (ML171) significantly blocks ECM degradation in DLD1 cells (2011) (0)
- Figure 1, LC-MS of probe ML178 (2011) (0)
- Cytoplasmic Cofilin-Actin Rods Isolation and Characterization of Cell Biology : (2010) (0)
- Inhibition de la salve respiratoire au moyen d'inhibiteurs de modification posttranslationnelle se rapportant a modification (1993) (0)
- Table 1, Overview of PubChem assays for NOX1 inhibitor project (2011) (0)
- Table 6, Summary (2010) (0)
- Generation by Human Neutrophils Suppression of Reactive Oxygen Species 2 in Reversion of the Adhesion-Mediated Critical Role of Proline-Rich Tyrosine Kinase (2005) (0)
- ADP-RIBOSYLATION OF THE REGULATORY COMPONENTS OF ADENYLATE CYCLASE1,2 (1983) (0)
- Faculty Opinions recommendation of Enhancement of learning and memory after activation of cerebral Rho GTPases. (2007) (0)
- ADDITIONS AND CORRECTIONS (2003) (0)
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What Schools Are Affiliated With Gary M. Bokoch?
Gary M. Bokoch is affiliated with the following schools:
