Gillian Murphy
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Communications
Gillian Murphy's Degrees
- Bachelors Dance University of North Carolina School of the Arts
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(Suggest an Edit or Addition)Gillian Murphy's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. (1987) (1223)
- Progress in matrix metalloproteinase research. (2008) (662)
- Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. (1991) (619)
- The ADAMs: signalling scissors in the tumour microenvironment (2008) (519)
- Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates. (1985) (446)
- Tissue inhibitors of metalloproteinases (2011) (409)
- Proteolysis and cell migration: creating a path? (1999) (406)
- Comparison of human stromelysin and collagenase by cloning and sequence analysis. (1986) (367)
- Matrix metalloproteinases in arthritic disease (2002) (319)
- Matrix metalloproteinases and their inhibitors. (1992) (314)
- Purification of rabbit bone inhibitor of collagenase. (1981) (306)
- Binding of gelatinases A and B to type-I collagen and other matrix components. (1995) (289)
- Tissue inhibitors of matrix metalloendopeptidases. (1995) (276)
- The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form. (1998) (242)
- Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling. (1999) (241)
- Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase. (1989) (230)
- [52] Mammalian collagenases (1981) (197)
- Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase. (1985) (197)
- Evidence that latent collagenases are enzyme-inhibitor complexes. (1977) (197)
- Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens. (1982) (196)
- Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3. (1998) (191)
- Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen. (1985) (175)
- Collagenase is a component of the specific granules of human neutrophil leucocytes. (1977) (174)
- Commitment to expression of the metalloendopeptidases, collagenase and stromelysin: relationship of inducing events to changes in cytoskeletal architecture (1986) (173)
- Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components. (1983) (165)
- The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. (1994) (164)
- The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor. (1983) (158)
- The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1. (1991) (156)
- The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes. (1980) (153)
- An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases. (1981) (153)
- Matrix metalloproteinases in disease and repair processes in the anterior segment. (2002) (147)
- Tissue Inhibitor of Metalloproteinase-3 Induces a Fas-associated Death Domain-dependent Type II Apoptotic Pathway* (2002) (144)
- Gelatinases A and B. (2002) (141)
- Cutting Edge: The Metalloproteinase ADAM17/TNF-α-Converting Enzyme Regulates Proteolytic Shedding of the MHC Class I-Related Chain B Protein1 (2009) (139)
- Phosphorylation-dependent Interactions between ADAM15 Cytoplasmic Domain and Src Family Protein-tyrosine Kinases* (2002) (137)
- Localization of the Death Domain of Tissue Inhibitor of Metalloproteinase-3 to the N Terminus (2000) (120)
- Current views of collagen degeradation. Progress towards understanding the resorption of connective tissues (1985) (119)
- Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin. (1981) (116)
- Localizing matrix metalloproteinase activities in the pericellular environment (2011) (116)
- Collagenolytic enzymes and their naturally occurring inhibitors. (1981) (113)
- Immunolocalization of tissue inhibitor of metalloproteinases (TIMP) in human cells. Characterization and use of a specific antiserum. (1985) (109)
- A gene delivery system activatable by disease-associated matrix metalloproteinases. (1997) (107)
- Clipping, shedding and RIPping keep immunity on cue. (2008) (104)
- Matrix metalloproteinases at a glance (2004) (103)
- Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse. (2002) (100)
- Regulation of the proteolytic disintegrin metalloproteinases, the 'Sheddases'. (2009) (98)
- Role of collagenase in mediating in vitro alveolar epithelial wound repair. (1999) (95)
- Characterization of a specific antiserum for mammalian collagenase from several species: immunolocalization of collagenase in rabbit chondrocytes and uterus. (1986) (94)
- Metalloproteinases and cancer invasion and metastasis. (1989) (89)
- Human diabetic corneas preserve wound healing, basement membrane, integrin and MMP-10 differences from normal corneas in organ culture. (2003) (87)
- Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue. (2003) (85)
- Elevated matrix metalloproteinase‐2 and ‐3 production from human diabetic dermal fibroblasts (2003) (84)
- Binding of latent and high Mr active forms of stromelysin to collagen is mediated by the C-terminal domain. (1991) (81)
- Gelatinase (type IV collagenase) immunolocalization in cells and tissues: use of an antiserum to rabbit bone gelatinase that identifies high and low Mr forms. (1989) (79)
- Extracellular Matrix Degradation (2003) (78)
- Characterization of a specific antiserum to rabbit stromelysin and demonstration of the synthesis of collagenase and stromelysin by stimulated rabbit articular chondrocytes. (1986) (77)
- Rabbit bone collagenase inhibitor blocks the activity of other neutral metalloproteinases. (1979) (75)
- Purification and characterization of human 72-kDa gelatinase (type IV collagenase). Use of immunolocalisation to demonstrate the non-coordinate regulation of the 72-kDa and 95-kDa gelatinases by human fibroblasts. (1991) (73)
- Tissue inhibitor of metalloproteinases (TIMP) regulates extracellular type I collagen degradation by chondrocytes and endothelial cells. (1987) (70)
- Collagen degradation and platelet-derived growth factor stimulate the migration of vascular smooth muscle cells. (2000) (67)
- The detection and characterisation of collagenase inhibitors from rabbit tissues in culture. (1977) (64)
- Human corneal epithelial cells require MMP-1 for HGF-mediated migration on collagen I. (2003) (62)
- A NEW FACTOR THAT MAY CONTROL COLLAGEN RESORPTION (1977) (61)
- Metalloproteinase inhibitors from bovine cartilage and body fluids. (1984) (57)
- Production of collagenase and inhibitor (TIMP) by normal, rheumatoid and osteoarthritic synovium in vitro: effects of hydrocortisone and indomethacin. (1981) (55)
- Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix. (2002) (53)
- Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone (2000) (53)
- Characterization of collagenase, other metallo-proteinases and an inhibitor (TIMP) produced by human synovium and cartilage in culture. (1981) (49)
- Cellular strategies for proteolytic targeting during migration and invasion (2001) (49)
- Effects of products from macrophages, blood mononuclear cells and or retinol on collagenase secretion and collagen synthesis in chondrocyte culture. (1982) (49)
- Relationship of procollagenase activator, stromelysin and matrix metalloproteinase 3. (1988) (46)
- Active gelatinase B is identified by histozymography in the cartilage resorption sites of developing long bones (1999) (45)
- [28] Gelatinases A and B (1995) (43)
- Proteinases in rheumatoid arthritis. (1992) (40)
- Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions (2008) (40)
- Degradation of glomerular basement membrane by purified mammalian metalloproteinases. (1988) (40)
- The role of plasminogen in cell-mediated collagen degradation. (1989) (36)
- Effects of retinol and dexamethasone on cytokine-mediated control of metalloproteinases and their inhibitors by human articular chondrocytes and synovial cells in culture. (1983) (33)
- Molecular studies on the connective tissue metalloproteinases and their inhibitor TIMP (1988) (32)
- Matrix metalloproteinases in the formation of human synovial joint cavities. (1996) (32)
- Cellular mechanisms for focal proteolysis and the regulation of the microenvironment (2000) (32)
- Inhibition of type I collagen film degradation by tumour cells using a specific antibody to collagenase and the specific tissue inhibitor of metalloproteinases (TIMP). (1985) (32)
- Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin (2013) (31)
- Tissue inhibitor of metalloproteinases. Identification of precursor forms synthesized by human fibroblasts in culture. (1985) (29)
- Rabbit models of arthritis: immunolocalization of matrix metalloproteinases and tissue inhibitor of metalloproteinase in synovium and cartilage. (1993) (28)
- Messenger function of prostaglandins in cell to cell interactions and control of proteinase activity in the rheumatoid joint. (1982) (23)
- Fell‐Muir Lecture: Metalloproteinases: from demolition squad to master regulators (2010) (23)
- Riding the metalloproteinase roller coaster (2017) (21)
- Proteinase induction by endothelial cells during wound repair. (1988) (14)
- Effects of corticosteroids on cellular interactions in human joint tissues in culture (1981) (13)
- The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis (2004) (12)
- Gelatinase A not alpha-secretase? (1994) (12)
- Mammalian collagenases. (1981) (11)
- Properties of rheumatoid and normal synovial tissue in vitro and cells derived from them (1982) (10)
- An inhibitor of mammalian collagenase from foetal rabbit bone in culture. (1977) (9)
- The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis (2004) (8)
- The Binding of Gelatinases A and B to Type I Collagen Yields Both High and Low Affinity Sites (1994) (8)
- DIPHOSPHONATES INHIBIT PRODUCTION OF PROSTAGLANDIN AND COLLAGENASE BY HUMAN-CELLS INVITRO (1981) (7)
- The effects of dexamethasone in vitro on the production of collagenase and inhibitor by synovial and cartilage explants from the joints of rabbits with a proliferative arthritis (2004) (6)
- Expression of MMPs and TIMPs in mammalian cells. (2001) (6)
- Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts. (1989) (6)
- Collagenase activity from cultured non-gravid rabbit uterus. (1977) (5)
- Influenza causing sunspots? (1990) (5)
- Expression of MMPs andTIMPs in Mammalian Cells (2001) (5)
- Matrix metalloproteinase expression in impaired wound healing (2000) (2)
- Gelatinase A not α-secretase? (1994) (2)
- Localization ofstromelysin geneexpression inatherosclerotic plaques byinsitu hybridization (1991) (2)
- The Biochemical and Cellular Functions of the Matrix Metalloproteinases (1996) (1)
- Relationship between Muller cell expression of MMP-1 and cell cycle progression (2002) (1)
- Studies on human fibroblast gelatinase (1988) (1)
- Interactions in connective tissues involving monocyte/macrophages and control of production of proteinases and proteinase inhibitors. (1982) (1)
- Matrix metalloproteinases: Where next? (1997) (1)
- Induction of a 95 kDA gelatinase in cultured smooth muscle cells from rabbit aorta (1992) (1)
- Characterisation of matrix metalloproteinase cleavage sites in fibrillin (2000) (1)
- HUMAN TUMOR-ASSOCIATED TRYPSIN(OGEN)-2 ACTIVATES 3 GENETICALLY DISTINCT BUT STRUCTURALLY HOMOLOGOUS HUMAN PRO-MATRIX METALLOPROTEINASES (1994) (1)
- The binding of rabbit bone inhibitor of collagenase to concanavalin A--Sepharose [proceedings]. (1980) (1)
- Factors Influencing Production of Enzymes by Human Synovium in vitro1 (1982) (1)
- Cerebrospinal fluid studies in arthritis. (1947) (1)
- Other Family Members in Tissues and Lacking Conserved Domains Predominantly Expressed in Reproductive MMP-23, a New Matrix Metalloproteinase Cloning and Characterization of Human ENZYMOLOGY: (2014) (0)
- The role of ADAM proteinases in shedding of EGFR ligands (2008) (0)
- Development and characterisation of viral vectors targeted to atherosclerotic plaques (2007) (0)
- Mouse model with impaired collagen X degradation at the chondro-osseous junction (2005) (0)
- PL2.2. Proteolytic enzymes (2008) (0)
- 769: Profiling and Localisation of the Matrix Metalloproteinases in Bladder Cancer (2005) (0)
- The role of matrix remodeling in endochondral ossification (2002) (0)
- Some specialists' views of connective tissue biochemistry: Extracellular Matrix Biochemistry edited by K. A. Piez and A. H. Reddi, Elsevier, 1984. $60.00/Dfl. 185.00 (xx + 473 pages) ISBN 0 444 00799 7 (1984) (0)
- CHAPTER 11 – Matrix Proteinases (2006) (0)
- Letter to the editor (0)
- Mechanisms of extracellular matrix turnover in normal and neoplastic cells. (1986) (0)
- A multi-functional role for MMP-9 in corneal epithelial cells? (2000) (0)
- Transforming growthfactor betamodulates theexpression of collagenase andmetalioproteinas e inhibitor (1987) (0)
- Inhibition of Matrix Metalloproteinases Reduces Scarring Following Experimental Glaucoma Filtration Surgery (2002) (0)
- expressing Z α1-antitrypsin (2013) (0)
- Role of matrix remodeling in endochondral bone formation (2003) (0)
- Potential roles of metalloproteinases in cell migration (2002) (0)
- Multiple interactions of corticosteroids with tissues of human joints (1980) (0)
- Evaluation of tissue inhibitors of matrix metalloproteinase as tumor imaging agents (2008) (0)
- Dimeric Inhibitors of Matrix Metalloproteinases: a new approach to the study of protein-protein interactions for a selective control of degenerative extracellular matrix processes (2004) (0)
- MMP-1 and MMP-2 are implicated in Myofibroblast mediated Collagen Contraction. (2001) (0)
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