Gordon N. Gill
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Gordon N. Gillbiology Degrees
Biology
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#12466
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Cell Biology
#389
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#399
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Neuroscience
#1345
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#1391
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Biochemistry
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#1525
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Biology
Gordon N. Gill's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Gordon N. Gill Influential?
(Suggest an Edit or Addition)Gordon N. Gill's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics (1999) (1096)
- A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. (1994) (955)
- The Enhanced Tumorigenic Activity of a Mutant Epidermal Growth Factor Receptor Common in Human Cancers Is Mediated by Threshold Levels of Constitutive Tyrosine Phosphorylation and Unattenuated Signaling* (1997) (620)
- C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. (1984) (549)
- Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor (1987) (528)
- Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. (1990) (402)
- Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells (1981) (382)
- Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. (1984) (369)
- Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity. (1984) (364)
- Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1 (1996) (361)
- Regulated Migration of Epidermal Growth Factor Receptor from Caveolae* (1999) (330)
- LIM Factor Lhx3 Contributes to the Specification of Motor Neuron and Interneuron Identity through Cell-Type-Specific Protein-Protein Interactions (2002) (326)
- A cyclic-3',5'-adenosine monophosphate dependent protein kinase from the adrenal cortex: comparison with a cyclic AMP binding protein. (1970) (304)
- Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation (1989) (302)
- The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. (1991) (287)
- Protein-Protein Interaction of Zinc Finger LIM Domains with Protein Kinase C* (1996) (244)
- Relation of epidermal growth factor receptor concentration to growth of human epidermoid carcinoma A431 cells. (1984) (242)
- Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms (1986) (241)
- Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development. (1996) (239)
- Inhibition of the receptor‐binding function of clathrin adaptor protein AP‐2 by dominant‐negative mutant μ2 subunit and its effects on endocytosis (1999) (232)
- On the mechanism of action of ACTH. (1971) (231)
- Small CTD Phosphatases Function in Silencing Neuronal Gene Expression (2005) (220)
- RGS-PX1, a GAP for Gαs and Sorting Nexin in Vesicular Trafficking (2001) (220)
- A Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5* (2003) (211)
- Receptor tyrosine kinases (1992) (209)
- Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies (1988) (201)
- Epidermal growth factor and its receptor (1987) (198)
- Functional analysis of the nuclear LIM domain interactor NLI (1997) (183)
- Production of an epidermal growth factor receptor-related protein. (1984) (178)
- Control of bovine adrenal cortical cell proliferation by fibroblast growth factor. Lack of effect of epidermal growth factor. (1977) (171)
- The Nuclear LIM Domain Interactor NLI Mediates Homo- and Heterodimerization of LIM Domain Transcription Factors* (1998) (170)
- Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor on Tyrosine 845 Is Required for Zinc-induced Ras Activation* (2002) (161)
- Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. (1990) (160)
- The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. (2006) (159)
- Endosomal localization and function of sorting nexin 1 (2002) (153)
- Endocytosis and Lysosomal Targeting of Epidermal Growth Factor Receptors Are Mediated by Distinct Sequences Independent of the Tyrosine Kinase Domain (*) (1995) (144)
- Effects of epidermal growth factor receptor concentration on tumorigenicity of A431 cells in nude mice. (1986) (142)
- Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor. (1985) (142)
- Immunoaffinity purification of the epidermal growth factor receptor. Stoichiometry of binding and kinetics of self-phosphorylation. (1984) (142)
- Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression (1990) (129)
- Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation. (1990) (128)
- Angiotensin stimulation of bovine adrenocortical cell growth. (1977) (123)
- Mitogenic Signaling by Ret/ptc2 Requires Association with Enigma via a LIM Domain* (1996) (120)
- Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides (2001) (119)
- Hormonal control of adrenocortical cell proliferation. Desensitization to ACTH and interaction between ACTH and fibroblast growth factor in bovine adrenocortical cell cultures. (1977) (119)
- Chip and apterous physically interact to form a functional complex during Drosophila development. (1999) (118)
- The EGF receptor: structure, regulation and potential role in malignancy. (1985) (114)
- LIM domain recognition of a tyrosine-containing tight turn. (1994) (114)
- Interaction between the epidermal growth factor receptor and phosphoinositide kinases. (1991) (113)
- Determinants for dephosphorylation of the RNA polymerase II C‐terminal domain by Scp1 (2006) (109)
- Role of epidermal growth factor‐stimulated protein kinase in control of proliferation of A431 cells (1982) (107)
- The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface. (2004) (106)
- Role of the receptor in the mechanism of action of adenosine 3':5'-cyclic monophosphate. (1971) (105)
- Nucleotide regulation of a eukaryotic protein synthesis initiation complex;. (1975) (104)
- Regulation of the ERBB-2 Promoter by RBPJκ and NOTCH* (1997) (102)
- Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. (1998) (102)
- Shc and Enigma Are Both Required for Mitogenic Signaling by Ret/ptc2 (1998) (102)
- Structure and function of LIM domains. (1998) (98)
- Specificity of LIM Domain Interactions with Receptor Tyrosine Kinases* (1996) (98)
- The PDZ Domain of the LIM Protein Enigma Binds to β-Tropomyosin (1999) (97)
- Association of Epidermal Growth Factor Receptors with Coated Pit Adaptins via a Tyrosine Phosphorylation-regulated Mechanism (*) (1995) (96)
- Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins. (1995) (95)
- Structural Features of LIM Kinase That Control Effects on the Actin Cytoskeleton* (1999) (95)
- Regulation of the fetal human adrenal cortex: effects of adrenocorticotropin on growth and function of monolayer cultures of fetal and definitive zone cells. (1981) (93)
- A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C (1992) (92)
- A negative feedback loop attenuates EGF-induced morphological changes (1991) (89)
- Alteration of epidermal growth factor receptor activity by mutation of its primary carboxyl-terminal site of tyrosine self-phosphorylation. (1988) (87)
- Phosphorylation of cardiac troponin by guanosine 3':5'-monophosphate-dependent protein kinase. (1978) (86)
- Endocytosis and mitogenic signaling. (1999) (85)
- A three-step purification procedure for protein kinase C: characterization of the purified enzyme. (1987) (82)
- Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF. (1982) (81)
- Purification and characterization of 3':5'-cyclic GMP-dependent protein kinase. (1976) (79)
- Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity (2009) (79)
- Growth and function of cultured bovine adrenocortical cells in a serum-free defined medium. (1982) (78)
- Mechanism of ACTH action. (1972) (77)
- Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor. (1993) (75)
- The intracellular tyrosine kinase domain of the epidermal growth factor receptor undergoes a conformational change upon autophosphorylation. (1994) (75)
- Characterization of adult bovine adrenocortical cells throughout their life span in tissue culture. (1978) (75)
- Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo. (1988) (74)
- RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. (2001) (73)
- Characterization of cultured bovine adrenocortical cells and derived clonal lines: regulation of steroidogenesis and culture life span. (1979) (72)
- Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor. (1990) (71)
- Coexpression of both alpha and beta subunits is required for assembly of regulated casein kinase II. (1991) (71)
- Metyrapone and antioxidants are required to maintain aldosterone synthesis by cultured bovine adrenocortical zona glomerulosa cells. (1982) (70)
- The enigma of LIM domains. (1995) (70)
- Phosphorylation of ribosome-associated protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase: location of the microsomal receptor and protein kinase. (1971) (69)
- Structural analysis of the transmembrane domain of the epidermal growth factor receptor. (1991) (69)
- T3 receptor suppression of Sp1-dependent transcription from the epidermal growth factor receptor promoter via overlapping DNA-binding sites. (1993) (69)
- Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor. (1989) (68)
- Guanosine 3':5'-monophosphate-dependent protein kinase from bovine lung. Subunit structure and characterization of the purified enzyme. (1977) (66)
- The LIM domain-only protein LMO4 is required for neural tube closure (2005) (65)
- The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells (2007) (64)
- Identification and characterization of a regulated promoter element in the epidermal growth factor receptor gene. (1990) (61)
- Direct binding of eps8 to the juxtamembrane domain of EGFR is phosphotyrosine- and SH2-independent. (1995) (60)
- Ribonuclease H (hybrid) in Escherichia coli. Identification and characterization. (1973) (58)
- Viewing serine/threonine protein phosphatases through the eyes of drug designers (2013) (57)
- The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. (1999) (57)
- Regulation of epidermal growth factor receptor gene expression. (1989) (57)
- Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase (1981) (56)
- Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. (1997) (55)
- Chip is an essential cofactor for apterous in the regulation of axon guidance in Drosophila. (2000) (55)
- Enhanced tumorigenesis of NR6 cells which express non-down-regulating epidermal growth factor receptors. (1991) (52)
- On the mechanism of action of adrenocorticotropic hormone: the binding of cyclic-3',5'-adenosine monophosphate to an adrenal cortical protein. (1969) (51)
- Differential effects of ACTH or 8‐Br‐cAMP on growth and replication in a functional adrenal tumor cell line (1977) (51)
- Regulation of ternary (Met-tRNAf - GTP - eukaryotic initiation factor 2) protein synthesis initiation complex formation by the adenylate energy charge. (1976) (51)
- Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor. (1991) (50)
- Induction of cultured bovine adrenocortical zona glomerulosa cell 17-hydroxylase activity by ACTH (1983) (49)
- Guanosine 3',5'-monophosphate-dependent protein kinase. (1979) (48)
- The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis. (1997) (48)
- Regulation of the epidermal growth factor receptor by phosphorylation (1985) (47)
- Structural analysis of cGMP-dependent protein kinase using limited proteolysis. (1980) (46)
- Separation and characterization of a phosphatidylinositol kinase activity that co-purifies with the epidermal growth factor receptor. (1985) (46)
- Structure and inducible regulation of the human c-erb B2/neu promoter. (1990) (45)
- Regulation of deoxyribonucleic acid synthesis in bovine adrenocortical cells in culture. (1979) (44)
- Regulation of glutamine and pyruvate oxidation in cultured adrenocortical cells by cortisol, antioxidants, and oxygen: Effects on cell proliferation (1981) (44)
- Activation of hormone-sensitive lipase and phosphorylase kinase by purified cyclic GMP-dependent protein kinase. (1977) (43)
- Determinants of the endosomal localization of sorting nexin 1. (2005) (43)
- Phosphorylation of high mobility group protein 14 by casein kinase II. (1985) (42)
- Positive cooperativity in guanosine 3':5'-monophosphate binding to guanosine 3':5'-monophosphate-dependent protein kinase. (1979) (42)
- Suppression of cultured bovine adrenocortical zona glomerulosa cell aldosterone synthesis by steroids and its prevention by antioxidants. (1983) (41)
- Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C‐terminal domain phosphatase, Scp1 (2010) (41)
- Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells (1985) (40)
- Adenosine 3',5'-monophosphate and protein kinase dependent phosphorylation of ribosomal protein. (1973) (39)
- Phosphorylation of high mobility group 14 protein by cyclic nucleotide-dependent protein kinases. (1982) (35)
- ACTH regulation of the adrenal cortex. (1976) (34)
- Identity of the in vivo phosphorylation site in high mobility group 14 protein in HeLa cells with the site phosphorylated by casein kinase II in vitro. (1983) (33)
- Analysis of morphology and receptor metabolism in clonal variant A431 cells with differing growth responses to epidermal growth factor (1983) (33)
- Aging of adrenocortical cells in culture. (1979) (30)
- Purification of the cAMP receptor protein by affinity chromatography. (1974) (29)
- Decoding the LIM development code. (2003) (28)
- A nuclear protein is required for thyroid hormone receptor binding to an inhibitory half-site in the epidermal growth factor receptor promoter. (1992) (28)
- Preferential regulation of protein synthesis initiation complex formation by purine nucleotides. (1976) (25)
- Regulation of EGF receptor expression and function (1990) (25)
- Hormonal regulation of initiation of DNA synthesis and of differentiated function in Y‐1 adrenal cortical cells (1977) (24)
- Regulation of cyclic nucleotide-dependent protein kinase activity by histones and poly(L-arginine). (1981) (23)
- Hormonal control of adrenal RNA polymerase activities. (1974) (23)
- Epidermal growth factor stimulates phosphorylation of RAF-1 independently of receptor autophosphorylation and internalization. (1991) (23)
- Regulation of responsiveness of cultured adrenal cells to adrenocorticotropin and prostaglandin E1: cell density, cell division, and inhibitors of protein synthesis. (1981) (22)
- Involvement of ErbB2 in the Signaling Pathway Leading to Cell Cycle Progression from a Truncated Epidermal Growth Factor Receptor Lacking the C-terminal Autophosphorylation Sites (*) (1996) (21)
- Receptor protein tyrosine kinases (2007) (21)
- A Pit Stop at the ER (2002) (20)
- Regulatory features of the epidermal growth factor receptor (1987) (20)
- Adrenocorticotropic hormone stimulation of adrenal RNA polymerase I and III activities. Nucleotide incorporation into internal positions and 3' chain termini. (1975) (20)
- THE ISOLATION OF A RECEPTOR FOR ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE (cAMP) FROM THE ADRENAL CORTEX: THE ROLE OF THE RECEPTOR IN THE MECHANISM OF ACTION OF cAMP * (1971) (19)
- Positive and negative regulatory elements in the human erbB-2 gene promoter. (1994) (19)
- Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor. (1988) (19)
- The use of affinity chromatography in purification of cyclic nucleotide receptor proteins. (1976) (19)
- Thyrotropin-stimulated phosphorylation of high mobility group protein 14 in vivo at the site catalyzed by cyclic nucleotide-dependent protein kinases in vitro. (1984) (18)
- Comparison of cyclic nucleotide specificity of guanosine 3',5'-monophosphate-dependent protein kinase and adenosine 3',5'-monophosphate-dependent protein kinase. (1979) (17)
- A Heterodimeric Nuclear Protein Complex Binds Two Palindromic Sequences in the Proximal Enhancer of the Human erbB-2 Gene (*) (1996) (17)
- Protein effects on the activity of guanosine 3':5'-monophosphate-dependent protein kinase. (1980) (16)
- Guanosine 3',5'-monophosphate receptor protein: separation from adenosine 3',5'-monophosphate receptor protein. (1975) (16)
- Purification of functionally active epidermal growth factor receptor protein using a competitive antagonist monoclonal antibody and competitive elution with epidermal growth factor. (1987) (15)
- Reversibility of the epidermal growth factor receptor self-phosphorylation reaction. Evidence for formation of a high energy phosphotyrosine bond. (1989) (14)
- Hormonal regulation of the adrenocortical cell. (1980) (13)
- Assay of cyclic nucleotide-dependent protein kinases. (1979) (13)
- Kinetics of cAMP inhibition of DNA synthesis in bovine adrenocortical cells (1980) (12)
- Effect of carboxyl terminal truncation on the tyrosine kinase activity of the epidermal growth factor receptor. (1992) (12)
- Adrenocorticotropic hormone regulation of adrenal RNA polymerases. Stimulation of nuclear RNA polymerase III. (1976) (12)
- Specific factors are required for kinase-dependent endocytosis of insulin receptors. (1994) (12)
- Expression and purification of the epidermal growth factor receptor extracellular domain utilizing a polycistronic expression system. (1993) (11)
- Regulation of gene expression by epidermal growth factor. (1991) (9)
- Comparison of protein phosphorylations in variant A431 cells with different growth responses to epidermal growth factor (1984) (9)
- Mutational Analysis of the Nucleotide Binding Site of the Epidermal Growth Factor Receptor and v-Src Protein-tyrosine Kinases* (1996) (9)
- The detection and characterization of cyclic AMP-receptor proteins in animal cells. (1974) (9)
- Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats. (1996) (9)
- Comparison of cyclic nucleotide binding to adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate-dependent protein kinases. (1979) (8)
- Analysis of substrate recognition determinants in a synthetic peptide containing the Tyr 1173 autophosphorylation site of the epidermal growth factor receptor. (1995) (7)
- Purification and properties of thyroid hormone receptor beta 1 expressed in Escherichia coli as a fusion protein. (1995) (7)
- Epidermal growth factor stimulates a protein tyrosine kinase which is separable from the epidermal growth factor receptor. (1993) (7)
- Bio-molecular architects: a scaffold provided by the C-terminal domain of eukaryotic RNA polymerase II (2010) (7)
- 3 Growth Factors and Their Receptors (1989) (7)
- Pharmacology of adrenal cortical hormones (1979) (6)
- Structural features of the 5' region of the human erbB-2 gene. (1993) (5)
- Analysis of functional domains in the epidermal growth factor receptor using site-directed mutagenesis. (1988) (5)
- Nucleotide regulation of protein synthesis. (1979) (3)
- Corrections - Adrenocorticotropic Hormone Regualtion of Adrenal RNA Poymerases. Stimulation of Nuclear RNA Polymerase III. (1977) (2)
- A comparison of the cyclic nucleotide-dependent protein kinases using chemical cleavage at tryptophan and cysteine. (1985) (2)
- A basic residue, Lys 782, composes part of the ATP-binding site on the epidermal growth factor receptor tyrosine kinase. (1999) (2)
- Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis (LHX genesynuclear LIM interactorycranial neural crestySchwann cellsysomite) (1998) (2)
- Loss of division potential in culture: aging or differentiation? (1980) (2)
- LIM Domain Genes (2001) (1)
- Adrenal Cortical Ribonuclease H (Hybrid) 1 (1975) (1)
- Comparison of the interaction of cyclic nucleotide-dependent protein kinases with mononucleosomes and free histones. (1981) (1)
- Protein modulation of cyclic nucleotide-dependent protein kinases. (1983) (1)
- Evolution of hormone-receptor systems : proceedings of the UCLA symposium held in Squaw Valley, California, March 14-20, 1982 (1983) (1)
- STUDIES OF THE cAMP RECEPTOR PROTEIN AND OF THE cAMP DEPENDENT PHOSPHORYLATION OF RIBOSOMAL PROTEIN (1973) (1)
- A hypothesis concerning the structure of cAMP-and cGMP-dependent protein kinases. (1977) (1)
- Identification of phosphorylation sites: use of the epidermal growth factor receptor. (1991) (1)
- Comparison of cAMP-dependent protein kinase in normal and Rous sarcoma virus transformed chick embryo fibroblasts. (1981) (1)
- [21] Protein modulation of cyclic nucleotide-dependent protein kinases (1983) (1)
- Molecular Recognition of Endocytic Codes in Receptor Tyrosine Kinases. (1995) (0)
- Adrenal Cortical Ribonuclease H (hybrid) (38494). (1975) (0)
- Effects of Epidermal Growth Factor Receptor Concentration on Tumorigenicity of A431 Cells in Nude Mice1 (2006) (0)
- Removal of the tyrosine kinase domain leads to constitutive internalization and lysosomal targeting of the EGF receptor (1993) (0)
- Growth factors, receptors and oncogenes. (1988) (0)
- FACTOR RECEPTOR USING SITE-DIRECTED MUTAGENESIS (1988) (0)
- Structure Functional analysis of the epidermal growth factor receptor (1993) (0)
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