George S. Roth

George S. Roth's AcademicInfluence.com Rankings

George S. Roth

Biology

#9130

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#12298

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Biology

George S. Roth's Degrees

PhD Biology University of California, Berkeley

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George S. Roth's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study (2012) (1005)
Caloric restriction improves health and survival of rhesus monkeys (2017) (550)
Biomarkers of Caloric Restriction May Predict Longevity in Humans (2002) (417)
Longevity: Extending the lifespan of long-lived mice (2001) (402)
Calorie restriction mimetics: an emerging research field (2006) (400)
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease (2004) (338)
Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes (*) (1996) (336)
Dopamine Induces Apoptosis through an Oxidation-involved SAPK/JNK Activation Pathway* (1998) (333)
Overexpression of dopamine D2 receptors reduces alcohol self‐administration (2001) (321)
Aging in Rhesus Monkeys: Relevance to Human Health Interventions (2004) (314)
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. (1996) (310)
Calorie restriction in rhesus monkeys (2003) (264)
A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. (2001) (264)
Promotion of wound repair in old mice by local injection of macrophages. (1989) (246)
Reduced β-adrenergic receptor concentrations in ageing man (1977) (242)
Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence. (1996) (236)
Caloric Restriction in Primates and Relevance to Humans (2001) (227)
Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons. (1996) (217)
Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates (2006) (213)
Development of Calorie Restriction Mimetics as a Prolongevity Strategy (2004) (200)
Age-related changes in the nigrostriatum: a behavioral and biochemical analysis. (1978) (200)
Calorie Restriction in Primates: Will It Work and How Will We Know? (1999) (197)
Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart. (1980) (175)
Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). (2006) (170)
Dehydroepiandrosterone sulfate: a biomarker of primate aging slowed by calorie restriction. (1997) (165)
Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization (2004) (163)
Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging (1995) (158)
Changes in the mechanisms of hormone and neurotransmitter action during aging: Current status of the role of receptor and post-receptor alterations. A review (1982) (153)
Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk. (1999) (148)
Dietary restriction retards the age-associated loss of rat striatal dopaminergic receptors. (1981) (145)
Caloric restriction mimetics: metabolic interventions. (2001) (144)
Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points. (1995) (141)
Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats. (1999) (127)
Metformin supplementation and life span in Fischer-344 rats. (2010) (125)
Activity Measures in Rhesus Monkeys on Long-Term Calorie Restriction (1997) (125)
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking. (2004) (123)
Calorie restriction mimetics: Can you have your cake and eat it, too? (2015) (123)
Caloric Restriction in Primates (2001) (115)
Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats. (2010) (111)
Delayed loss of striatal dopamine receptors during aging of dietarily restricted rats (1984) (111)
D2 Dopamine Receptors Stimulate Mitogenesis Through Pertussis Toxin‐Sensitive G Proteins and Ras‐Involved ERK and SAP/JNK Pathways in Rat C6‐D2L Glioma Cells (1998) (109)
Effect of aging on concentrations of D2-receptor-containing neurons in the rat striatum (1989) (106)
Effect of age on sensitivity to pain and brain opiate receptors (1981) (106)
2-Deoxy-D-Glucose Feeding in Rats Mimics Physiologic Effects of Calorie Restriction (1998) (106)
Effect of aging on striatal dopamine receptor subtypes in Wistar rats (1986) (102)
Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells. (1997) (102)
Age-related changes in specific glucocorticoid binding by steroid-responsive tissues of rats. (1974) (100)
Hormone action during aging: Alterations and mechanisms (1979) (98)
beta-Adrenergic regulation of protein phosphorylation and its relationship to exocrine secretion in dispersed rat parotid gland acinar cells. (1981) (97)
Short-term calorie restriction improves disease-related markers in older male rhesus monkeys (Macaca mulatta) (2000) (89)
Glycolytic inhibition as a strategy for developing calorie restriction mimetics (2011) (89)
Cellular and Molecular Mechanisms of Impaired Dopaminergic Function during Aging (1994) (89)
Strategy for identifying biomarkers of aging in long-lived species (2001) (86)
Caloric restriction and aging in primates: Relevance to humans and possible CR mimetics (2002) (84)
Beyond the rodent model: Calorie restriction in rhesus monkeys (1997) (81)
Cellular proliferation potential during aging and caloric restriction in rhesus monkeys (Macaca mulatta) (1999) (80)
The roles of dopamine oxidative stress and dopamine receptor signaling in aging and age-related neurodegeneration. (2000) (78)
Caloric Restriction Mimetics: The Next Phase (2005) (77)
Loss of D2 receptors during aging is partially due to decreased levels of mRNA (1991) (74)
The potential for dietary restriction to increase longevity in humans: extrapolation from monkey studies (2006) (74)
Studies of aging in ames dwarf mice: Effects of caloric restriction (2000) (74)
Dietary restriction in aging nonhuman primates. (2007) (72)
Wound repair in mice as influenced by age and antimacrophage serum. (1987) (72)
Dietary Restriction in Nonhuman Primates: Progress Report on the NIA Study (1992) (68)
Caloric restriction increases HDL2 levels in rhesus monkeys ( Macaca mulatta). (1997) (67)
Aging and food restriction alter some indices of bone metabolism in male rhesus monkeys (Macaca mulatta). (1995) (66)
The role of peroxisomes in aging (1998) (66)
Effect of aging on recovery of striatal dopamine receptors following N-ethoxycarbonyl-2-ethoxy-1, 2-dihydroquinoline (EEDQ) blockade. (1984) (65)
Alterations in muscarinic control of striatal dopamine autoreceptors in senescence: a deficit at the ligand-muscarinic receptor interface? (1988) (65)
Age-dependent regulation of mammalian DNA synthesis and cell proliferation In vivo (1972) (65)
Slowing ageing by caloric restriction (1995) (64)
Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat. (1981) (63)
Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata (1990) (63)
Loss of D2 Receptor Binding with Age in Rhesus Monkeys: Importance of Correction for Differences in Striatal Size (1999) (62)
Reductions in glucocorticoid inhibition of glucose oxidation and presumptive glucocorticoid receptor content in rat adipocytes during aging. (1976) (62)
Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta) (2001) (61)
Testing the theories of aging (1982) (60)
K+ release from rat parotid cells: An α1-adrenergic mediated event (1982) (59)
Modulation of rat parotid cell alpha-adrenergic responsiveness at a step subsequent to receptor activation. (1982) (58)
A strategy for identifying biomarkers of aging: further evaluation of hematology and blood chemistry data from a calorie restriction study in rhesus monkeys (1998) (58)
Dietary caloric restriction prevents the age-related decline in plasma melatonin levels of rhesus monkeys. (2001) (57)
The serious search for an anti-aging pill. (2002) (56)
Age-related decline in striatal volume in monkeys as measured by magnetic resonance imaging (2000) (55)
Age related changes in hormone binding by target cells and tissues; Possible role in altered adaptive responsiveness (1975) (55)
Dopamine induces apoptosis in cultured rat striatal neurons; possible mechanism of D2‐dopamine receptor neuron loss during aging (1995) (55)
Effects of dietary caloric restriction and aging on thyroid hormones of rhesus monkeys. (2002) (55)
Energy restriction does not alter bone mineral metabolism or reproductive cycling and hormones in female rhesus monkeys. (2001) (54)
Energy balance in rhesus monkeys (Macaca mulatta) subjected to long-term dietary restriction. (1995) (54)
Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats (1998) (53)
Decrement of muscarinic receptor-stimulated low-K M GTPase in striatum and hippocampus from the aged rat (1992) (51)
Age-related decline in Ras/ERK mitogen-activated protein kinase cascade is linked to a reduced association between Shc and EGF receptor. (2000) (50)
Multiple transduction mechanisms are likely involved in calcium-mediated exocrine secretory events in rat parotid cells. (1983) (50)
Evaluating measures of hematology and blood chemistry in male rhesus monkeys as biomarkers of aging (1994) (50)
Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging (1995) (50)
Balanced Macromolecular Biosynthesis in “Protoplasts” of Streptococcus faecalis (1971) (49)
Reduced glucocorticoid binding site concentration in cortical neuronal perikarya from senescent rats (1976) (49)
Reduced beta-adrenergic receptor concentrations in ageing man. (1977) (48)
Testosterone secretion in the rat in response to chorionic gonadotrophin: alterations with age. (1978) (48)
Caloric Restriction Mimetics (2007) (47)
A nonhuman primate model of age-related bone loss: a longitudinal study in male and premenopausal female rhesus monkeys. (2001) (47)
Effect of Caloric Restriction on the 24‐Hour Plasma DHEAS and Cortisol Profiles of Young and Old Male Rhesus Macaques (2004) (46)
β-adrenergic regulation of rat parotid gland exocrine protein secretion during aging (1981) (46)
Changes in tissue responsiveness to hormones and neurotransmitters during aging (1995) (46)
Physiological levels of β-amyloid peptide promote PC12 cell proliferation (1996) (45)
Effects of long-term diet restriction on aging and longevity in primates remain uncertain. (2004) (45)
The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates. (2003) (45)
Calorie restriction and skeletal mass in rhesus monkeys (Macaca mulatta): evidence for an effect mediated through changes in body size. (2001) (45)
Life-long dietary restriction affects striatally-mediated behavioral responses in aged rats (1983) (44)
Nutritional modulation of aging in nonhuman primates. (1999) (44)
Calorie Restriction in Nonhuman Primates: Implications for Age-Related Disease Risk (1998) (44)
Manipulation of health span and function by dietary caloric restriction mimetics (2016) (43)
Effect of aging on EGF stimulated DNA synthesis and EGF receptor levels in primary cultured rat hepatocytes. (1993) (43)
Upregulation of Striatal Dopamine Receptors and Improvement of Motor Performance in Senescence (1988) (42)
Age-related decline in caloric intake and motivation for food in rhesus monkeys (2005) (42)
Age-related impairment in rat parotid cell alpha 1-adrenergic action at the level of inositol trisphosphate responsiveness. (1988) (42)
Human implications of caloric restriction's effects on aging in laboratory animals: an overview of opportunities for research. (2001) (41)
In vivo imaging of adenovirus‐mediated over‐expression of dopamine D2 receptors in rat striatum by positron emission tomography (2000) (41)
Death of PC12 cells and hippocampal neurons induced by adenoviral‐mediated FAD human amyloid precursor protein gene expression (1999) (41)
Decreased striatal D2 dopamine receptor mRNA synthesis during aging. (1993) (39)
Reduced glucocorticoid responsiveness and receptor concentration in splenic leukocytes of senescent rats. (1975) (39)
Measures of body size and growth in rhesus and squirrel monkeys subjected to long‐term dietary restriction (1995) (39)
Locomotor activity in female rhesus monkeys: assessment of age and calorie restriction effects. (2000) (39)
Caloric restriction mimetics: a novel approach for biogerontology. (2007) (38)
Effect of aging on striatal dopamine receptor subtype recovery following N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline blockade and relation to motor function in Wistar rats (1987) (38)
Age-related changes in activation of mitogen-activated protein kinase cascades by oxidative stress. (1998) (38)
Telomere dynamics in rhesus monkeys: no apparent effect of caloric restriction. (2011) (38)
Physiological levels of β-amyloid peptide stimulate protein kinase C in PC12 cells (1997) (37)
Muscarinic acetylcholine receptor subtype mRNA expression and ligand binding in the aged rat forebrain (1991) (37)
Effect of aging on populations of estrogen receptor-containing cells in the rat uterus. (1989) (37)
Effect of age and caloric restriction on cutaneous wound closure in rats and monkeys. (1997) (37)
Effect of aging on prolactin regulation of rat striatal dopamine receptor concentrations. (1983) (36)
Assessment of auditory function in rhesus monkeys (Macaca mulatta): effects of age and calorie restriction (2004) (36)
Dietary restriction in Rhesus monkeys: Lymphopenia and reduced mitogen-induced proliferation in peripheral blood mononuclear cells (1997) (36)
Age-related changes in cytokine production by leukocytes in rhesus monkeys (2001) (35)
Peroxisomal disease cell lines with cellular plasmalogen deficiency have impaired muscarinic cholinergic signal transduction activity and amyloid precursor protein secretion. (1998) (35)
The striatal dopaminergic system as a model for modulation of altered neurotransmitter action during aging: effects of dietary and neuroendocrine manipulations. (1986) (35)
Cytokine responses in young and old rhesus monkeys: effect of caloric restriction. (2002) (35)
Breath ethane as a marker of reactive oxygen species during manipulation of diet and oxygen tension in rats. (1999) (35)
Area specific alterations in muscarinic stimulated low K m GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction (1994) (34)
Reduction of motor behavioural deficits in senescence via chronic prolactin or estrogen administration: time course and putative mechanisms of action (1989) (34)
Differential Effect of Aging on Cholesterol Modulation of Carbachol-Stimulated Low-K m GTPase in Striatal Synaptosomes (1998) (34)
Plasma concentrations of glucose, insulin, and percent glycosylated hemoglobin are unaltered by food restriction in rhesus and squirrel monkeys. (1992) (33)
Aging and Caloric Restriction in Nonhuman Primates (2001) (33)
Effects of calorie restriction on reproductive and adrenal systems in Japanese quail: Are responses similar to mammals, particularly primates? (2005) (32)
Changes in G Protein‐mediated Signal Transduction in Aging and Alzheimer's Disease (1993) (32)
Adenovirus-mediated gene transfer of dopamine D2 receptor cDNA into rat striatum. (1995) (31)
Age changes in signal transduction and gene expression (1997) (30)
Altered coupling of alpha 1-adrenergic receptor-G protein in rat parotid during aging. (1992) (30)
The effects of aging on muscarinic receptor/G-protein coupling in the rat hippocampus and striatum (1992) (30)
Dietary Restriction and Life-Span (2002) (30)
Modulation of rat striatal membrane fluidity: effects on age related differences in dopamine receptor concentrations. (1986) (29)
In vivo assessment of adenoviral vector‐mediated gene expression of dopamine D2 receptors in the rat striatum by positron emission tomography (2002) (29)
Age-related decline in striatal volume in rhesus monkeys: assessment of long-term calorie restriction (2004) (28)
Changes in the mechanisms of steroid action during aging. (1979) (27)
Loss of rat ventricular α1-adrenergic receptors during aging (1982) (27)
Mechanisms of Altered Hormone and Neurotransmitter Action during Aging: The Role of Impaired Calcium Mobilization (1987) (27)
Age-associated changes in nuclear binding of rat uterine estradiol receptor complexes. (1985) (27)
Caloric Restriction and Longevity (2009) (27)
Accuracy and precision of dual‐energy X‐ray absorptiometry for body composition measurements in rhesus monkeys * (2001) (27)
Dissociation of Striatal GTPase and Dopamine Release Responses to Muscarinic Cholinergic Agonists in F344 Rats: Influence of Age and Dietary Manipulation (1995) (26)
Physiological levels of beta-amyloid peptide promote PC12 cell proliferation. (1996) (26)
Changes in hormone binding and responsiveness in target cells and tissues during aging. (1975) (25)
Decrease in rat uterine estrogen receptors during aging: physio- and immunochemical properties. (1981) (25)
Effects of Moderate Calorie Restriction on Testosterone Production and Semen Characteristics in Young Rhesus Macaques (Macaca mulatta)1 (2010) (24)
Age-specific alterations in muscarinic stimulation of K+-evoked dopamine release from striatal slices by cholesterol andS-adenosyl-l-methionine (1995) (24)
Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study (1996) (24)
Relationship between plasma ghrelin, insulin, leptin, interleukin 6, adiponectin, testosterone and longevity in the Baltimore Longitudinal Study of Aging (2011) (23)
Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes. (1998) (23)
Possible changes in tissue sensitivity in the age-dependent stimulation of DNA synthesis in vivo. (1973) (23)
Muscarinic receptor concentrations and dopamine release in aged rat striata (1992) (23)
Age-related alterations in the number and function of pituitary lactotropic cells from intact and ovariectomized rats. (1986) (22)
Effects of thyroid hormones on cardiac hypertrophy and β-adrenergic receptors during aging (1981) (22)
Iron-56 Irradiation Diminishes Muscarinic but Not α 1 -Adrenergic-Stimulated Low-K m GTPase in Rat Brain (1994) (22)
Rotational behavior produced by adenovirusmediated gene transfer of dopamine D2 receptor into rat striatum (1997) (22)
Aging of the striatum: mechanisms and interventions (2008) (22)
Accelerated wound repair in old deer mice (Peromyscus maniculatus) and white-footed mice (Peromyscus leucopus). (1987) (22)
Selective susceptibility of cultured striatal neurons to kainic acid (1992) (22)
Hormone receptor changes during adulthood and senescence: significance for aging research. (1979) (22)
Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life (2005) (21)
Altered Striatal Dopaminergic and Cholinergic Reciprocal Inhibitory Control and Motor Behavioral Decrements in Senescence (1988) (21)
Impaired adrenergic stimulation of rat parotid cell glucose oxidation during aging: the role of calcium. (1986) (21)
Nutritional Interventions in Aging and Age‐Associated Diseases (2007) (21)
Caloric Restriction and Caloric Restriction Mimetics: Current Status and Promise for the Future (2005) (20)
Ionophore A23187 partially reverses LH secretory defect of pituitary cells from old rats. (1987) (20)
7 Hormonal Regulation of Motor Behavior in Senescence (1993) (20)
Effects of Phentermine and Phenformin on Biomarkers of Aging in Rats (2004) (19)
Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta) (2014) (19)
Influence of age, sex, and dietary restriction on intracellular free calcium responses of CD4+ lymphocytes in rhesus monkeys (Macaca mulatta) (1995) (19)
Adrenergic and cholinergic mediated glucose oxidation by rat parotid gland acinar cells during aging. (1981) (19)
Effect of long-term caloric restriction and exercise on muscle bioenergetics and force development in rats. (1999) (19)
Dehydroepiandrosterone sulfate (DHEAS) as an endocrine marker of aging in calorie restriction studies (2013) (19)
Changes in prostaglandin E1 stimulation of glucose oxidation in rat adipocytes during maturation and aging. (1981) (19)
Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics (2020) (18)
Reduced DNA synthesis in primary cultures of hepatocytes from old mice is restored by thymus grafts. (1998) (18)
Altered proteins and aging (1983) (18)
Effects of in vivo estradiol administration on availability of rat uterine nuclear acceptor in measured in vitro. (1984) (18)
Age-dependent regulation of mammalian DNA synthesis and cell division in vivo by glucocorticoids. (1974) (18)
Age-related impairment in striatal muscarinic cholinergic signal transduction is associated with reduced membrane bilayer width measured by small angle X-ray diffraction. (1995) (18)
Dietary restriction slows age pigment accumulation in the retinal pigment epithelium. (1993) (18)
Age‐related changes in DNA synthesis stimulated by epinephrine and isoproterenol in primary cultured rat hepatocytes (1994) (18)
Application of gene therapy to treat age-related loss of dopamine D2 receptor (1998) (18)
Dopamine stimulates redox–tyrosine kinase signaling and p38 MAPK in activation of astrocytic C6-D2L cells (1999) (18)
Alpha1-adrenergic stimulation of phosphatidylinositol-phosphatidic acid turnover in rat parotid cells. (1982) (17)
Altered Ovarian Regulation of Wound Healing during Aging (1981) (17)
Solubilization of striatal D-2 dopamine receptors: evidence that apparent loss during aging is not due to membrane sequestration. (1986) (16)
The Roy Walford legacy: diet restriction from molecules to mice to monkeys to man and onto mimetics (2004) (16)
Age-related changes in transcriptional and posttranscriptional regulation of the dopaminergic system. (1994) (16)
Progress in the Development of Caloric Restriction Mimetic Dietary Supplements (2001) (16)
Impact of Moderate Calorie Restriction on the Reproductive Neuroendocrine Axis of Male Rhesus Macaques. (2010) (16)
The deleterious effects of aging and kainic acid may be selective for similar striatal neuronal populations (1991) (16)
Isolated uterine nuclei and cytosol receptors of aged rats exhibit impaired estrogenic stimulation of RNA polymerase II. (1984) (16)
Peculiarities of the effect of hormones and transmitters during aging: modulation of changes in dopaminergic action. (1988) (16)
Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta). J Med Primatol 30:161–173, 2001 (2004) (15)
Reduction of motor behavioral deficits in senescent animals via chronic prolactin administration I. Rotational behavior (1986) (15)
Mannoheptulose: glycolytic inhibitor and novel caloric restriction mimetic (2009) (14)
Dissociation of glucocorticoid inhibition of glucose transport and metabolism by increase in adipocyte age and/or size. (1979) (14)
Decreased signal transduction in rat parotid cell aggregates during aging is not due to loss of alpha1-adrenergic receptors (1989) (14)
Calcium Homeostasis and Aging: Role in Altered Signal Transduction (1989) (14)
The Effect of Aging on Rat Striatal D1 Receptor mRNA-Containing Neurons (1997) (14)
Pathological Characterization of Male Wistar Rats From The Gerontology Research Center (1993) (14)
Decreased estrogenic stimulation of RNA polymerase II in aged rat uteri is apparently due to reduced nuclear binding of receptor-estradiol complexes. (1985) (13)
Parathyroid hormone stimulates phosphate efflux through an apparently adenosine 3',5'-monophosphate-independent process in rat parotid cell aggregates. (1986) (13)
Biochemistry of Aging (1999) (13)
Effect of specific membrane perturbations on alpha 1-adrenergic and muscarinic-cholinergic signal transduction in rat parotid cell aggregates. (1994) (12)
Biological activity of avocado‐derived mannoheptulose in dogs (2010) (11)
Effects of Aging and Long‐Term Calorie Restriction on DHEA and DHEA Sulfate in Rhesus Monkeys (1995) (11)
Modification of ATP-dependent Ca2+ transport in rat parotid basolateral membranes during aging (1988) (11)
Discordant effects of aging on prolactin and luteinizing hormone-beta messenger ribonucleic acid levels in the female rat. (1990) (11)
Age-dependent regulation of isoproterenol-stimulated DNA synthesis in rat salivary gland in vivo. (1974) (11)
Biosynthetic rates of proteins having the characteristics of glucocorticoid receptors in adipocytes of mature and senescent rats. (1981) (11)
Molecular mechanisms of impaired stimulation of DNA synthesis in cultured hepatocytes of aged rats. (1998) (10)
Longitudinal study of aging in monkeys: Effects of diet restriction (1993) (10)
Regulation of isoproterenol-stimulated DNA synthesis in rat salivary gland in vivo by adrenal glucocorticoids. (1974) (10)
Similar effects of saponin treatment and aging on coupling of α 1-adrenergic receptor-G-protein (1993) (10)
Effect of aging on regulation of sdi-1 in rat hepatocytes. (1996) (10)
Evidence for an alteration in the microsomal Ca2+ release mechanism in senescent rat parotid acinar cells. (1989) (10)
Endocrine and neuroendocrine mechanisms of aging (1982) (10)
Mechanisms of altered hormone-neurotransmitter action during aging: from receptors to calcium mobilization. (1990) (10)
Interaction of hormones with receptors and alterations of these processes with age. (1980) (9)
Age changes in adrenergic and dopaminergic signal transduction mechanisms: Parallels and contrasts (1988) (9)
Reinterpretation of the ESR Spectra of Membrane Protein Spin Labels. (1982) (9)
Changes in Hormone Action with Age: Altered Calcium Mobilization and/or Responsiveness Impairs Signal Transduction (1990) (9)
Caloric restriction increases HDL2 levels in rhesus monkeys (Macaca mulatta). (1997) (9)
Decreased m3-Muscarinic and α1-Adrenergic Receptor Stimulation of PIP2 Hydrolysis in Parotid Gland Membranes from Aged Rats: Defect in Activation of Gαq/11 (1995) (9)
Impaired conversion of rat uterine estradiol receptors during aging (1986) (9)
Receptors and Aging (1984) (9)
Excess in vitro prolactin secretion by pituitary cells from ovariectomized old rats. (1984) (9)
Effects of age on control of lipolysis during fasting. (1981) (8)
Entropy theories of aging revisited (1994) (8)
Adrenergic-agonist-induced Ca2+ fluxes in rat parotid cells are not Na+-dependent. (1985) (8)
Calorie Restriction in Nonhuman Primates: Impact on Aging, Disease, and Frailty (2005) (8)
Age‐related decrease in repair of oxidative damage to surface sulfhydryl groups on rat adipocytes (1980) (8)
Development of an adenoviral vector for intracerebral delivery of the dopamine D2 receptor (2000) (8)
Longitudinal follow-up study of adenoviral vector-mediated gene transfer of dopamine d2 receptors in the striatum in young, middle-aged, and aged rats: a positron emission tomography study (2003) (8)
Interaction of nuclear factors from young and old rat brain regions with regulatory sequences of the D2 dopamine receptor gene promoter. (1997) (7)
Primate Models for Dietary Restriction Research (1991) (7)
Impaired Down-Regulation of Pituitary Dopamine Receptors by Estradiol in Aged Rats (1989) (7)
Alpha 1-adrenergic and muscarinic-cholinergic stimulated inositol trisphosphate production may proceed through different post-receptor signal transduction pathways in parotid acini. (1991) (7)
Are free radicals causes or effects of aging? The entropy theory (1993) (7)
Loss of rat ventricular alpha 1-adrenergic receptors during aging. (1982) (7)
α 1-Adrenergic stimulation of low K m GTPase in rat striata is diminished with age (1992) (7)
Effect of cholesterol content in diet on capillary flow of rat erythrocytes. Part I: geometric and flow characteristics. (1997) (6)
Dissociation of alpha-adrenergic and cholinergic stimulated inositol trisphosphate-dependent calcium mobilization at the "post-receptor" level. (1989) (6)
Effects of calorie restriction on chromosomal stability in rhesus monkeys (Macaca mulatta) (2007) (6)
Changes in Hormone Action during Aging: Glucocorticoid Regulation of Adipocyte Glucose Metabolism and Catecholamine Regulation of Myocardial Contractility (1980) (6)
Effect of cholesterol content in diet on capillary flow of rat erythrocytes. Part II: mechanical properties. (1997) (6)
Alpha 1-adrenergic responsiveness of young adult and aged rat submandibular cells in vitro. (1985) (6)
The Serious Search for an Antiaging Pill (2004) (6)
Altered Biochemical Responsiveness and Hormone Receptor Changes during Aging (1978) (6)
Effect of aging on EGF‐stimulated replication of specific genes in rat hepatocytes (1998) (6)
Endocrine Effects of Dietary Restriction and Aging: The National Institute on Aging Study (2001) (6)
EFFECT OF LONG-TERM DIETARY RESTRICTION OF THE SOMATOTROPHIC AXIS IN ADULTAND AGED MONKEYS (1995) (5)
Impaired estrogen stimulation of RNA polymerase II activity in uterine nuclei of senescent rats (1984) (5)
ALTERED HORMONE/NEUROTRANSMITTER ACTION DURING AGING: RECEPTOR AND POST-RECEPTOR CHANGES (1984) (5)
Iron-56 irradiation diminishes muscarinic but not alpha 1-adrenergic-stimulated low-Km GTPase in rat brain. (1994) (5)
Effect of aging on vulnerability of striatal D1 And D2 dopamine receptor-containing neurons to kainic acid (1997) (5)
CHOLINERGIC SYSTEMS IN AGING: THE ROLE OF OXIDATIVE STRESS (1992) (5)
Aging and the Effect of Calorie Restriction in Rhesus Monkeys (2010) (5)
α1-Adrenoceptors in parotid cells: age does not alter the ratio of α1A and α1B subtypes (1992) (4)
The Rhesus Macaque as a Model of Human Aging and Age-Related Disease (2006) (4)
Mechanisms of age-related changes in gonadotropin-releasing hormone receptor messenger ribonucleic acid content in the anterior pituitary of male rats (1999) (4)
Effect of long-term caloric restriction and exercise on muscle bioenergetics and force development in rats. (1999) (4)
Loss of muscarinic regulation of striatal dopamine function in senescence (1992) (4)
Intracellular localization of ribosome biosynthesis in osmotically fragile forms of Streptococcus faecalis. (1971) (4)
Hormonal regulation of motor behavior in senescence. (1993) (4)
Measurements of Mitochondrial Oxygen Radical Production (1998) (4)
Chapter 9 Changes in Neurotransmitter Signal Transduction Pathways in the Aging Brain (1997) (4)
Incorporation of Radioactive Macromolecular Precursors into Intact Cells and Osmotically Stabilized “Protoplasts” of Streptococcus faecalis (1971) (4)
Age-associated loss of beta adrenergic receptors from human lymphocytes in vivo [proceedings]. (1978) (3)
K+ release from rat parotid cells: an alpha 1-adrenergic mediated event. (1982) (3)
Effects of aging on the lipid order and composition of rat adipocyte ghosts (1985) (3)
Effects of age and sex on basal and dopamine-inhibited in vitro prolactin release, and dopamine receptor binding, by the rat adenohypophysis (1993) (3)
Calorie Restriction Mimetics: Progress and Potential (2015) (3)
Bioavailability of avocado‐derived mannoheptulose in dogs (2010) (3)
In Vitro biosynthesis of adipocyte proteins having the characteristics of glucocorticoid receptors. (1980) (3)
Stimulation of parotid cell glucose oxidation. Role of alpha 1-adrenergic receptors and calcium mobilization. (1983) (3)
History of the Study of Calorie Restriction in Nonhuman Primates Conducted by the National Institute on Aging: The First Decade (2015) (2)
Nutritional Modulation of Aging by Caloric Restriction (2002) (2)
Effects of aging and dietary restriction on activity of monkey serum in promoting fibroblast migration (1995) (2)
Dietary and Neuroendocrine Modulation of Age Related Changes in Dopaminergic Action During Aging (1987) (2)
Accommodative function in rhesus monkeys: effects of aging and calorie restriction (2005) (2)
Ovarian reserve tests and their utility in predicting response to controlled ovarian stimulation in rhesus monkeys (2010) (2)
Functional recovery of the striatal cholinergic system in aged rats by adenoviral vector-mediated gene transfer of dopamine D2 receptor (2006) (2)
Partial restoration of impaired alpha1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment (1995) (2)
Effects of aging on mechanisms of alpha-adrenergic and dopaminergic action. (1986) (2)
The Nathan W. Shock memorial lectureship (1994) (2)
Age-related changes in the mechanisms of LHRH-stimulated LH release from pituitary cells in vitro (1992) (2)
Possible "Anti-Aging" Effects of Caloric Restrictions as Indicated by Dehydroepiandrosterone Sulfate Levels (2000) (1)
Characterization and Mechanisms of Action of Avocado Extract Enriched in Mannoheptulose as a Candidate Calorie Restriction Mimetic. (2021) (1)
Molecular mechanisms of impaired stimulation of DNA synthesis in cultured hepatocytes of aged rats. (1998) (1)
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11. (1995) (1)
Relationship between Plasma Ghrelin, Insulin, Leptin, IL6, Adiponectin, Testosterone and Longevity in the Baltimore Longitudinal Study of Aging (2011) (1)
Potential Health Benefits of Avocados (2013) (1)
Aging reduces the numbers of hepatocytes synthesizing DNA in response to EGF and epinephrine. (1997) (1)
Altered estrogen action in the senescent rat uterus: a model for steroid resistance during aging. (1986) (1)
Oxidative Stress and Reduced Receptor Responsiveness in Senescence (1994) (1)
Oxidative Stress and the Loss of Receptor Sensitivity in Aging (1995) (1)
EFFECTS OF AGING ON THE MECHANISMS OF ESTROGEN ACTION IN RAT UTERUS (1986) (1)
An Avocado Extract Enriched in Mannoheptulose Prevents the Negative Effects of a High-Fat Diet in Mice (2021) (1)
Changes in Hormone Receptors During Aging: Role in Altered Hormonal Responsiveness (1979) (1)
Hormonal receptor and responsiveness changes during aging: genetic modulation. (1978) (0)
Plasticity and Aging (1999) (0)
The standard calibration instrument automation system for the atomic absorption spectrophotometer. Part 3: Program documentation (1982) (0)
Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta) (2013) (0)
The possible role of protein degradation in altered membrane structure and function (1984) (0)
Overview on Aging (1999) (0)
Alpha 1-adrenoceptors in parotid cells: age does not alter the ratio of alpha 1A and alpha 1B subtypes. (1992) (0)
Aging Pigments and Membranes (1999) (0)
Experimental Manipulations of Brain Aging (1999) (0)
Tolerance and safety of an avocado‐based ingredient for adult dogs (2012) (0)
Neurotransmitters and Receptors (2003) (0)
Stimulation of glucose oxidation in rat submandibular gland cells in vitro by analogues of cyclic AMP. (1985) (0)
Changes in Transmembrane Signaling Mechanisms During Aging — Cellular and Molecular Aspects (2017) (0)
Reply (1995) (0)
Mammals Are Not the Only Animal Models for Aging (1999) (0)
Age-ralated changes in GnRH receptor RNA content in the anterior pituitary of male rats (1997) (0)
Instability in the Nuclear and Mitochondrial Genomes (1999) (0)
Age-related impairment and thymus- induced recovery of DNA synthesis in primary cultures of hepatocytes (1995) (0)
Age-Related Changes in Hormone Action: The Role of Hormone Receptors (2017) (0)
Mechanisms of Altered Hormone-Neurotransmitter Action During Aging: From Receptors to Calcium Mobilization (1990) (0)
Program Scientific Session 1 : Clinical Cytogenetics (2004) (0)
Similar effects of saponin treatment and aging on coupling of alpha 1-adrenergic receptor-G-protein. (1993) (0)
Diet Restriction and Diet Restriction Mimetics: An anti-aging strategy for canines? (2010) (0)
Amyloid f 3-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons ( acetylcholine / Alzheimer disease / antioxidant / calcium / carbachol ) (2005) (0)
| Endocrine and Neuroendocrine Mechanisms Of Aging | Taylor & Francis Group (2017) (0)
Receptor changes and the control of hormone action during aging. (1980) (0)
Dopamine Stimulates Astrocytic C6‐D2L Cells via Tyrosine Kinase and p38 MAPK Activation (2000) (0)
Effects of aging on parathyroid hormones stimulated ionic fluxes in rat parotid cell aggregates (1987) (0)
Response to Dr. Jeffrey Halter (1988) (0)
Erratum: Overexpression of dopamine D2 receptors reduces alcohol self-administration (Journal of Neurochemistry 78 (1094-1103)) (2008) (0)
ATP-Dependent CA2+ Transport in Rat Parotid Basolateral Membranes is Reduced with Aging (1986) (0)
IMPACT OF MODERATE CALORIE RESTRICTION ON PITUITARY GENE EXPRESSION IN ADULT MALE RHESUS MACAQUES (Macaca mulatta) (2007) (0)
Interventions in Aging and Age-Related Diseases: The Present and the Future (2006) (0)
An ultraviolet-visible spectrophotometer automation system. Part 3: Program documentation (1982) (0)
Receptor and Postreceptor Changes During Lymphocyte Aging (1988) (0)
Neuroendocrinology and Sleep During Aging (1999) (0)
Receptors, Recognition and Ageing (1979) (0)
Changes in Receptors and Signal Transduction Events during Aging (1990) (0)

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What Schools Are Affiliated With George S. Roth?

George S. Roth is affiliated with the following schools:

University of Maryland, College Park
University of Kentucky
Weizmann Institute of Science
Case Western Reserve University