Gerald Salen
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Gerald Salen's Degrees
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Gerald Salen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. (1994) (766)
- Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption (2001) (688)
- Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. (2002) (419)
- Interruption of the enterohepatic circulation of bile acids in man: comparative effects of cholestyramine and ileal exclusion on cholesterol metabolism. (1971) (401)
- Metabolism of β-sitosterol in man (1970) (389)
- Defective cholesterol biosynthesis in Smith-Lemli-Opitz syndrome (1993) (362)
- Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively. (2001) (337)
- Long-term treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid. (1984) (322)
- Mechanisms of action of clofibrate on cholesterol metabolism in patients with hyperlipidemia. (1972) (286)
- Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia (2004) (285)
- Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT (2003) (276)
- Dietary beta-sitosterol as an internal standard to correct for cholesterol losses in sterol balance studies. (1968) (230)
- Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence. (2005) (227)
- Lethal atherosclerosis associated with abnormal plasma and tissue sterol composition in sitosterolemia with xanthomatosis. (1985) (214)
- Cholestanol deposition in cerebrotendinous xanthomatosis. A possible mechanism. (1971) (195)
- Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis. (1989) (195)
- A biochemical abnormality in cerebrotendinous xanthomatosis. Impairment of bile acid biosynthesis associated with incomplete degradation of the cholesterol side chain. (1974) (189)
- Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption. (1998) (182)
- Bile acid biosynthesis (1974) (178)
- Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. (1998) (175)
- Ursodeoxycholic acid for the treatment of primary sclerosing cholangitis: A 30‐month pilot study (1991) (170)
- Clinical effects of cholesterol supplementation in six patients with the Smith-Lemli-Opitz syndrome (SLOS) (1997) (165)
- The metabolism of cholestanol, cholesterol, and bile acids in cerebrotendinous xanthomatosis. (1973) (159)
- Hepatic cholesterol metabolism in patients with gallstones. (1975) (159)
- 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. (2001) (156)
- A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol (2004) (153)
- Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria. (1979) (143)
- Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes. (1995) (137)
- Ursodeoxycholic acid: a safe and effective agent for dissolving cholesterol gallstones. (1982) (136)
- A Multicenter Placebo-controlled Clinical Trial of Oral Metoclopramide in Diabetic Gastroparesis (1983) (134)
- Correlation of severity and outcome with plasma sterol levels in variants of the Smith-Lemli-Opitz syndrome. (1995) (132)
- Treatment of Smith-Lemli-Opitz syndrome: results of a multicenter trial. (1997) (130)
- Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat. (2006) (126)
- Markedly increased tissue concentrations of 7-dehydrocholesterol combined with low levels of cholesterol are characteristic of the Smith-Lemli-Opitz syndrome. (1995) (125)
- Metabolism of ursodeoxycholic acid in man. (1977) (124)
- Increased formation of ursodeoxycholic acid in patients treated with chenodeoxycholic acid. (1974) (122)
- Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations. (2002) (121)
- Increased plasma cholestanol and 5 alpha-saturated plant sterol derivatives in subjects with sitosterolemia and xanthomatosis. (1985) (120)
- Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance (2003) (119)
- Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. (2010) (112)
- Metabolism of beta-sitosterol in man. (1970) (111)
- Side chain conjugation prevents bacterial 7-dehydroxylation of bile acids. (1990) (108)
- Effect of high and low doses of ursodeoxycholic acid on gallstone dissolution in humans. (1980) (107)
- Epidemiology, diagnosis, and treatment of cerebrotendinous xanthomatosis (CTX) (2017) (105)
- A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis. (1990) (105)
- Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice Published, JLR Papers in Press, February 16, 2003. DOI 10.1194/jlr.M200489-JLR200 (2003) (104)
- Human cholesterol 7a-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype (2018) (100)
- Increased sitosterol absorption is offset by rapid elimination to prevent accumulation in heterozygotes with sitosterolemia. (1992) (99)
- Characterization of serum and urinary bile acids in patients with primary biliary cirrhosis by gas-liquid chromatography-mass spectrometry: effect of ursodeoxycholic acid treatment. (1989) (98)
- Determination of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in man. (1974) (97)
- Abnormal cholesterol metabolism in the Smith-Lemli-Opitz syndrome: report of clinical and biochemical findings in four patients and treatment in one patient. (1994) (95)
- Increased concentrations of cholestanol and apolipoprotein B in the cerebrospinal fluid of patients with cerebrotendinous xanthomatosis. Effect of chenodeoxycholic acid. (1987) (92)
- A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat. (1976) (92)
- Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome. (1995) (91)
- Highly simplified method for gas-liquid chromatographic quantitation of bile acids and sterols in human stool. (1999) (91)
- Chenodeoxycholic acid inhibits increased cholesterol and cholestanol synthesis in patients with cerebrotendinous xanthomatosis. (1975) (90)
- Spectrum of Delta(7)-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome. (2000) (88)
- Effect of ursodeoxycholic acid and chenodeoxycholic acid on cholesterol and bile acid metabolism. (1986) (88)
- Cholic acid biosynthesis: the enzymatic defect in cerebrotendinous xanthomatosis. (1979) (88)
- Determination of hepatic cholesterol 7α-hydroxylase activity in man (1974) (87)
- Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat. (1992) (87)
- Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase. (1988) (85)
- Effect of ursodeoxycholic acid on bile acid metabolism in primary biliary cirrhosis (1989) (81)
- PREVENTION OF CHENODEOXYCHOLIC-ACID TOXICITY WITH LINCOMYCIN (1975) (81)
- Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome. (1995) (78)
- Side Chain Hydroxylations in Bile Acid Biosynthesis Catalyzed by CYP3A Are Markedly Up-regulated in Cyp27−/− Mice but Not in Cerebrotendinous Xanthomatosis* (2001) (78)
- Defective conversion of 7-dehydrocholesterol to cholesterol in cultured skin fibroblasts from Smith-Lemli-Opitz syndrome homozygotes. (1995) (77)
- Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis. (2006) (76)
- Malabsorption in intestinal scleroderma. Relation to bacterial flora and treatment with antibiotics. (1966) (76)
- Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake. (2003) (75)
- Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. (2002) (74)
- FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade. (2005) (73)
- Osteoporosis and increased bone fractures in cerebrotendinous xanthomatosis. (1993) (71)
- Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines (2003) (69)
- Fine-mapping, mutation analyses, and structural mapping of cerebrotendinous xanthomatosis in U.S. pedigrees. (2001) (69)
- Prenatal detection of the cholesterol biosynthetic defect in the Smith-Lemli-Opitz syndrome by the analysis of amniotic fluid sterols. (1995) (69)
- Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies. (1976) (69)
- Response to diet and cholestyramine in a patient with sitosterolemia. (1990) (67)
- Simultaneous quantitation of fatty acids, sterols and bile acids in human stool by capillary gas-liquid chromatography. (2002) (67)
- Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendinous xanthomatosis. (2018) (67)
- Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits. (1995) (66)
- Reproducing abnormal cholesterol biosynthesis as seen in the Smith-Lemli-Opitz syndrome by inhibiting the conversion of 7-dehydrocholesterol to cholesterol in rats. (1995) (65)
- Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX. (2001) (65)
- Acute hemolytic anemia complicating viral hepatitis in patients with glucose-6-phosphate dehydrogenase deficiency. (1966) (65)
- Identification of pentahydroxy bile alcohols in cerebrotendinous xanthomatosis: characterization of 5beta-cholestane-3alpha, 7alpha, 12alpha, 24xi, 25-pentol and 5beta-cholestane-3alpha, 7alpha, 12alpha, 23xi, 25-pentol. (1975) (63)
- Ursodeoxycholic acid treatment of bile reflux gastritis. (1985) (62)
- Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits. (2000) (62)
- Bile acid synthesis. (1983) (61)
- Enrichment of the more hydrophilic bile acid ursodeoxycholic acid in the fecal water-soluble fraction after feeding to rats with colon polyps. (1998) (61)
- Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7 alpha-hydroxylase. (2004) (60)
- Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction. (1991) (59)
- The effect of increased hepatic sitosterol on the regulation of 3‐hydroxy‐3‐methylglutaryl—coenzyme a reductase and cholesterol 7α‐hydroxylase in the rat and sitosterolemic homozygotes (1994) (58)
- Detection of a common mutation in the RSH or Smith-Lemli-Opitz syndrome by a PCR-RFLP assay: IVS8-G-->C is found in over sixty percent of US propositi. (2000) (56)
- Role of taurine in feeding the low-birth-weight infant. (1984) (56)
- Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann–Pick type C phenotype (1998) (55)
- Bile alcohol metabolism in man. Conversion of 5beta-cholestane-3alpha, 7alpha,12alpha, 25-tetrol to cholic acid. (1975) (55)
- Substrate specificity of cholylglycine hydrolase for the hydrolysis of bile acid conjugates. (1984) (53)
- Role of CYP27A in cholesterol and bile acid metabolism Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400219-JLR200 (2005) (51)
- Comparison of Changes in Lipid Profile after Bilio-intestinal Bypass and Gastric Banding in Patients with Morbid Obesity (2005) (50)
- Regulation of bile acid synthesis. Measurement of cholesterol 7 alpha-hydroxylase activity in rat liver microsomal preparations in the absence of endogenous cholesterol. (1981) (49)
- The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis. (1988) (48)
- Comparative effects of lovastatin and chenodeoxycholic acid on plasma cholestanol levels and abnormal bile acid metabolism in cerebrotendinous xanthomatosis. (1994) (48)
- Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function. (1990) (48)
- Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7alpha-hydroxylase and 27-hydroxylase activities in rat liver. (1999) (47)
- A unique patient with coexisting cerebrotendinous xanthomatosis and beta-sitosterolemia. (1981) (47)
- Sitosterolemia: exclusion of genes involved in reduced cholesterol biosynthesis. (1998) (46)
- An improved method for the isolation, quantitation, and identification of bile acids in rat feces (1975) (46)
- Abnormal high density lipoproteins in cerebrotendinous xanthomatosis. (1981) (45)
- Increasing dietary cholesterol induces different regulation of classic and alternative bile acid synthesis. (1999) (44)
- Dietary cholesterol stimulates CYP7A1 in rats because farnesoid X receptor is not activated. (2004) (44)
- Regulation of cholesterol 7 alpha-hydroxylase by hepatic 7 alpha-hydroxylated bile acid flux and newly synthesized cholesterol supply. (1991) (44)
- Effect of chenodeoxycholic acid on biliary and urinary bile acids and bile alcohols in cerebrotendinous xanthomatosis; monitoring by high performance liquid chromatography. (1985) (44)
- Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid in the rhesus monkey: Biochemical and ultrastructural studies (1978) (43)
- Sitosterol and cholesterol metabolism in a patient with coexisting phytosterolemia and cholestanolemia. (1983) (42)
- Fetal Smith‐Lemli‐Opitz syndrome can be detected accurately and reliably by measuring amniotic fluid dehydrocholesterols (1998) (42)
- Inborn errors of bile acid synthesis. (1977) (42)
- Psychiatric disorders in patients with cerebrotendinous xanthomatosis. (1988) (41)
- The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats (2003) (41)
- Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J × CASA/Rk intercross (2002) (41)
- Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7alpha-hydroxylase activities in the rat, guinea pig, and rabbit: effects of cholesterol and bile acids. (1999) (40)
- Metabolism of iso-bile acids in the rat. (1982) (40)
- Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes. (1998) (39)
- Regulation of the Farnesoid X Receptor (FXR) by Bile Acid Flux in Rabbits* (2002) (39)
- Relationship between biliary and serum bile acids and response to ursodeoxycholic acid in patients with primary biliary cirrhosis (1998) (39)
- Peripheral neuropathy in cerebrotendinous xanthomatosis. (1985) (38)
- Synthesis of 5beta-cholestane-3alpha, 7alpha, 12alpha, 25-tetrol and 5beta-cholestane-3alpha, 7alpha, 245, 25-pentol. (1976) (38)
- Gas chromatography of bile acids. (1999) (38)
- Stereospecific side chain hydroxylations in the biosynthesis of chenodeoxycholic acid. (1978) (38)
- Thin-layer chromatography of conjugated bile acids. (1979) (37)
- Regulation of rat hepatic 3beta-hydroxysterol delta7-reductase: substrate specificity, competitive and non-competitive inhibition, and phosphorylation/dephosphorylation. (1998) (37)
- Splenic Injury as a Complication of Colonoscopy: A Case Series (2008) (37)
- Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26. (1985) (37)
- Gas-liquid chromatography-mass spectrometry of trimethylsilyl ethers of bile alcohols. (1978) (36)
- Relationship between abnormal cholesterol synthesis and retarded learning in rats. (1998) (36)
- Fine mapping of a gene responsible for regulating dietary cholesterol absorption; founder effects underlie cases of phytosterolaemia in multiple communities (2001) (36)
- Feedback regulation of bile-acid synthesis in the rat. Differing effects of taurocholate and tauroursocholate. (1990) (36)
- Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin. (1990) (35)
- Fetal demise with Smith–Lemli–Opitz syndrome confirmed by tissue sterol analysis and the absence of measurable 7‐dehydrocholesterol Δ7‐reductase activity in chorionic villi (2000) (34)
- FXR-mediated down-regulation of CYP7A1 dominates LXRalpha in long-term cholesterol-fed NZW rabbits. (2003) (34)
- Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbits. (1997) (34)
- Increased plasma bile alcohol glucuronides in patients with cerebrotendinous xanthomatosis: effect of chenodeoxycholic acid. (1987) (33)
- Results of a phase I multiple-dose clinical study of ursodeoxycholic Acid. (2004) (33)
- Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment. (2001) (33)
- Fecal bile acid concentrations in a subpopulation of the wheat bran fiber colon polyp trial. (2003) (32)
- Early Morphologic and Enzymatic Changes in Livers of Rats Treated with Chenodeoxycholic and Ursodeoxycholic Acids (2007) (30)
- Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid in the rhesus monkey. Biochemical and ultrastructural studies. (1978) (30)
- Transformation of 4-cholesten-3-one and 7α-hydroxy-4-cholesten-3-one into cholestanol and bile acids in cerebrotendinous xanthomatosis (1984) (30)
- Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice. (2001) (30)
- The Smith-Lemli-Opitz syndrome: a potentially fatal birth defect caused by a block in the last enzymatic step in cholesterol biosynthesis. (1997) (30)
- Treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid (1985) (30)
- Effect of long-term treatment with ursodiol on clinical and biochemical features and biliary bile acid metabolism in patients with primary biliary cirrhosis. (1993) (30)
- Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis. (1994) (29)
- Cerebrotendinous xanthomatosis as a multisystem disease mimicking premature ageing. (1991) (29)
- Lithium hydroxide/aqueous methanol: mild reagent for the hydrolysis of bile acid methyl esters (1990) (29)
- Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion. (1998) (29)
- Cerebrotendinous xanthomatosis: a rare cause of bilateral Achilles tendon swelling and ataxia. A case report. (2006) (29)
- Measurement of 3 beta-hydroxysteroid delta 7-reductase activity in cultured skin fibroblasts utilizing ergosterol as a substrate: a new method for the diagnosis of the Smith-Lemli-Opitz syndrome. (1996) (28)
- Identification of 19-nor-5,7,9(10)-cholestatrien-3 beta-ol in patients with Smith-Lemli-Opitz syndrome. (1995) (28)
- Sterol concentrations in cultured Smith-Lemli-Opitz syndrome skin fibroblasts: diagnosis of a biochemically atypical case of the syndrome. (1997) (28)
- Preparation of 24(R)- and 24(S)-5beta-cholestane-3alpha,7alpha,24-triols and 25(R)- and 25(S)-5beta-cholestane-3alpha,7alpha,26-triols by a hydroboration procedure. (1978) (27)
- Biliary bile acids, bile alcohols, and sterols of Alligator mississippiensis. (1980) (27)
- Purification of cholesterol 7 alpha-hydroxylase from human and rat liver and production of inhibiting polyclonal antibodies. (1990) (27)
- Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia. (1998) (27)
- Antenatal Therapy of Smith-Lemli-Opitz Syndrome (1999) (26)
- Treatment of the cholesterol biosynthetic defect in Smith-Lemli-Opitz syndrome reproduced in rats by BM 15.766. (1995) (26)
- Comparative effects of cholestanol and cholesterol on hepatic sterol and bile acid metabolism in the rat. (1984) (26)
- A bile alcohol sulfate as a major component in the bile of the small skate (Raja erinacea). (1989) (26)
- Tuberous Xanthomas in Sitosterolemia (2000) (26)
- Biochemical abnormalities in cerebrotendinous xanthomatosis. (1991) (26)
- Letter Prevention of chenodeoxycholic-acid toxicity with lincomycin. (1975) (26)
- Biosynthesis of 5 -cholestan-3 -ol in cerebrotendinous xanthomatosis. (1972) (26)
- Significance of plasma 7α-hydroxy-4-cholesten-3-one and 27-hydroxycholesterol concentrations as markers for hepatic bile acid synthesis in cholesterol-fed rabbits☆ (2004) (25)
- Normal cognition and behavior in a Smith‐Lemli‐Opitz syndrome patient who presented with Hirschsprung disease (2003) (25)
- Increasing hepatic cholesterol 7α‐hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits (1996) (25)
- Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats. (2005) (25)
- Microwave-induced organic reactions of bile acids: Esterification, deformylation and deacetylation using mild reagents (1995) (25)
- Selective reduction of oxo bile acids: synthesis of 3 beta-, 7 beta-, and 12 beta-hydroxy bile acids. (1991) (25)
- Chenodeoxycholic acid normalizes elevated lipoprotein secretion and catabolism in cerebrotendinous xanthomatosis. (1989) (25)
- Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria (Myocastor coypus). (1986) (24)
- Screening for abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome: rapid determination of plasma 7-dehydrocholesterol by ultraviolet spectrometry. (1997) (24)
- Abnormal hepatic sinusoidal bile acid transport in an Amish kindred is not linked to FIC1 and is improved by ursodiol. (2000) (24)
- p-Toluenesulfonic acid/methanol: Mild reagent for the preparation of bile acid methyl esters (1981) (24)
- Aneurysmal coronary artery disease in cerebrotendinous xanthomatosis. (1988) (23)
- Treatment of cholesterol gallstones with litholytic bile acids. (1991) (23)
- Biosynthesis of cholesterol, lanosterol, and delta 7-cholestenol, but not cholestanol, in cultured fibroblasts from normal individuals and patients with cerebrotendinous xanthomatosis. (1982) (23)
- Glycocholic acid and glycodeoxycholic acid but not glycoursocholic acid inhibit bile acid synthesis in the rabbit. (1992) (23)
- Absolute configuration of pentahydroxy bile alcohols excreted by patients with cerebrotendinous xanthomatosis: a circular dichroism study. (1978) (23)
- Biosynthesis of chenodeoxycholic acid in man: stereospecific side-chain hydroxylations of 5beta-cholestane-3alpha,7alpha-diol. (1978) (23)
- Rapid identification of Smith-Lemli-Opitz syndrome homozygotes and heterozygotes (carriers) by measurement of deficient 7-dehydrocholesterol-delta 7-reductase activity in fibroblasts. (1997) (22)
- Cholesterol 7α‐hydroxylase activities from human and rat liver are modulated in vitro posttranslationally by phosphorylation/dephosphorylation (1996) (22)
- Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig. (1990) (22)
- Toxicity of chenodeoxycholic acid in the rhesus monkey. (1975) (22)
- Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α‐hydroxylase and sterol 27‐hydroxylase (1995) (21)
- Sitosterolemia: opposing effects of cholestyramine and lovastatin on plasma sterol levels in a homozygous girl and her heterozygous father. (1996) (21)
- Configuration at C-25 in 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid by X-ray crystallography. (1979) (21)
- Developmental sensitivity of associative learning to cholesterol synthesis inhibitors (2002) (21)
- Hypercholesterolemia in rats with hepatomas: Increased oxysterols accelerate efflux but do not inhibit biosynthesis of cholesterol (2006) (20)
- Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis. (2004) (20)
- Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects. (2000) (20)
- Smith-Lemli-Opitz syndrome in Japan. (1998) (20)
- Configuration at C-25 in 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid isolated from human bile. (1983) (19)
- Preparation of [3β-3H] labeled bile acids and bile alcohols (1979) (19)
- Removal of the bile acid pool upregulates cholesterol 7alpha-hydroxylase by deactivating FXR in rabbits. (2002) (19)
- Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α-hydroxylase and sterol 27-hydroxylase (1995) (19)
- Comparative effect of dietary sitosterol on plasma sterols and cholesterol and bile acid synthesis in a sitosterolemic homozygote and heterozygote subject. (1997) (18)
- Regulation of early cholesterol biosynthesis in rat liver: Effects of sterols, bile acids, lovastatin, and BM 15.766 on 3‐hydroxy‐3‐methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities (1998) (18)
- Identification of 5α-stanols in patients with sitosterolemia and xanthomatosis: stereochemistry of the protonolysis of steroidal organoboranes. (1982) (18)
- Efficacy and safety of ezetimibe 40 mg vs. ezetimibe 10 mg in the treatment of patients with homozygous sitosterolaemia (2008) (18)
- Intrahepatic pigment and crystal forms in patients with cerebrotendinous xanthomatosis (CTX) (1978) (18)
- Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes (1996) (18)
- Rapid hydrogenation of unsaturated sterols and bile alcohols using microwaves (1997) (17)
- The natural history of phytosterolemia: Observations on its homeostasis. (2017) (16)
- The Metabolism of Sterols and Bile Acids in Cerebrotendinous Xanthomatosis (1976) (16)
- The use of microwave oven for the rapid hydrolysis of bile acid methyl esters. (1991) (16)
- Synthesis of Steroidal Pyrimidines (1996) (16)
- Cleavage of the taurine conjugate of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid by rat fecal bacteria. (1979) (15)
- Analysis of the Effect of Intestinal Resection on Rat Ileal Bile Acid Transporter Expression and on Bile Acid and Cholesterol Homeostasis (2002) (15)
- Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin. (2001) (15)
- Evidence for the early reduction of the 24,25 double bond in the conversion of lanosterol to cholesterol in cerebrotendinous xanthomatosis. (1977) (14)
- Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis Published, JLR Papers in Press, December 1, 2004. DOI 10.1194/jlr.M400256-JLR200 (2005) (14)
- EEG in Cerebrotendinous Xanthomatosis (CTX) (1982) (14)
- FGF15/19 protein levels in the portal blood do not reflect changes in the ileal FGF15/19 or hepatic CYP7A1 mRNA levels (2013) (14)
- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts. (2000) (14)
- Metabolism of potential precursors of chenodeoxycholic acid in cerebrotendinous xanthomatosis (CTX). (1979) (14)
- Effect of 7-ketolithocholic acid on bile acid metabolism in humans. (1982) (14)
- TOXICITY OF CHENODEOXYCHOLIC ACID IN RHESUS MONKEYS (1974) (14)
- The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model. (2012) (14)
- The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension (2005) (14)
- Lithotripsy plus ursodiol is superior to ursodiol alone for cholesterol gallstones. (1992) (13)
- DIAGNOSIS OF SMITH-LEMLI-OPITZ SYNDROME. AUTHORS' REPLY (1994) (13)
- Oral dissolution treatment of gallstones with bile acids. (1990) (13)
- Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids. (1981) (13)
- Capillary gas-liquid chromatographic separation of bile alcohols. (1992) (13)
- Significance of plasma 7alpha-hydroxy-4-cholesten-3-one and 27-hydroxycholesterol concentrations as markers for hepatic bile acid synthesis in cholesterol-fed rabbits. (2004) (12)
- Synthesis of biological precursors of cholic acid (1978) (12)
- Regulation of cholesterol biosynthetic pathway in patients with the Smith–Lemli–Opitz syndrome (2000) (12)
- Synthesis and structure of 26 (or 27)-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24S,25 xi-pentol isolated from the urine and feces of a patient with sitosterolemia and xanthomatosis. (1985) (12)
- MICROWAVE-INDUCED RAPID SYNTHESIS OF BILE ACID CONJUGATES (1995) (12)
- Bile acid abnormalities in cholestatic liver diseases. (1999) (12)
- The fecal bile acids and sterols of Alligator mississippiensis. (1981) (12)
- Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations. (2001) (12)
- Bile acid biosynthesis. Pathways and regulation. (1974) (11)
- Two novel mutations in the sterol 27‐hydroxylase gene causing cerebrotendinous xanthomatosis (2002) (11)
- Microwave-induced rapid synthesis of sarcosine conjugated bile acids (1995) (11)
- Cholic acid biosynthesis: conversion of 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol into 5beta-cholestane-3alpha,7alpha, 12alpha,24beta,25-pentol by human and rat liver microsomes. (1977) (11)
- Use of external shock-wave lithotripsy and adjuvant ursodiol for treatment of radiolucent gallstones (1989) (11)
- Biosynthesis of Bile Acids in Cerebrotendinous Xanthomatosis (1985) (11)
- Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice. Assay of enzyme activities by high-resolution gas chromatography;-mass spectrometry. (2000) (11)
- Cerebrotendinous xanthomatosis: A cause of cataracts and tendon xanthoma. (1982) (11)
- Capillary gas chromatographic analysis of serum bile acids as the n-butyl ester-trimethylsilyl ether derivatives. (1998) (11)
- Use of positive ion fast atom bombardment mass spectrometry for rapid identification of a bile alcohol glucuronide isolated from cerebrotendinous xanthomatosis patients (1990) (11)
- Inverse relationship between plasma cholestanol concentrations and bile acid synthesis in sitosterolemia. (1994) (11)
- Blocking cholesterol synthesis impairs acquisition of the classically conditioned eyeblink response (2000) (10)
- A facile synthesis of (3α-3H]β-sitosterol (1983) (10)
- Capillary gas-liquid chromatography of 6-hydroxylated bile acids. (1995) (10)
- The stimulatory effect of LXRα is blocked by SHP despite the presence of a LXRα binding site in the rabbit CYP7A1 promoter Published, JLR Papers in Press, February 17, 2006. (2006) (10)
- Transformation of 5 alpha-cholest-7-en-3 beta-ol to cholesterol and cholestanol in cerebrotendinous xanthomatosis. (1974) (10)
- C26-Analogs of naturally occurring C27 bile alcohols. (1976) (10)
- Configurational assignment of 5β-cholestane-3α, 7α, 12α, 23, 25-pentol excreted by patients with cerebrotendinous xanthomatosis (a circular dichroism study) (1979) (10)
- Stereospecific synthesis of 3 beta-hydroxylated bile alcohols. (1984) (10)
- Asymmetric syntheses and lanthanide-induced CD studies of (24R and 24S) 5β-cholestane-3α,7α,12α,24,25-pentols (1994) (9)
- Bile alcohol glucuronides: regioselective O-glucuronidation of 5β-cholestane-3α,7α,12α,25-tetrol and 24-nor-5β-cholestane-3α,7α,12α,25-tetrol (1993) (9)
- LDL-apheresis cannot be recommended for treatment of cerebrotendinous xanthomatosis (1994) (9)
- 7β-hydroxy bile alcohols: Facile synthesis and 2D 1H NMR studies of 5β-cholestane-3α,7β,12α,25-tetrol (1997) (9)
- Configuration at C-25 in 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25,26-pentol excreted by patients with cerebrotendinous xanthomatosis: circular dichroism and 13C-NMR studies. (1986) (9)
- Gallstone dissolution therapy with ursodiol (1989) (9)
- Chemical ionization-mass spectrometric approach to structure determination of an intermediate in bile acid biosynthesis. (1982) (9)
- Chemical synthesis, structural analysis, and decomposition of N-nitroso bile acid conjugates. (1996) (9)
- Sonographic gallstone patterns are of value in predicting the outcome of biliary lithotripsy. (1991) (9)
- Thin-Layer Chromatography of Bile Alcohols, Bile Acids and Conjugated Bile Acids (1980) (9)
- Synthesis of [3α-3H]7-dehydrocholesterol via stable tritiated 4-phenyl-1,2,4-triazoline-3,5-dione derivative (1997) (9)
- Campestanol (24-methyl-5α-cholestan-3β-ol) absorption and distribution in New Zealand white rabbits: Effect of dietary sitostanol (1999) (8)
- An overlapping binding site in the CYP7A1 promoter allows activation of FXR to override the stimulation by LXRalpha. (2007) (8)
- Synthesis of 3α,6β,7a,12β- and 3α,6β,7β,12β-tetrahydroxy-5β-cholanoic acids (1992) (8)
- Gallstone formation in cholestanol-fed mice. (1993) (8)
- Regulation of the last two enzymatic reactions in cholesterol biosynthesis in rats: Effects of BM 15.766, cholesterol, cholic acid, lovastatin, and their combinations (1996) (8)
- Differentiation between the 25R- and 25S-isomers of 5 beta-cholestane-3 alpha, 7 alpha, 26-triol by 13C NMR spectroscopy. (1980) (8)
- Liver in cerebrotendinous xanthomatosis (CTX)--a histochemical and EM study of four cases. (1980) (8)
- Accurate detection of Smith–Lemli–Opitz syndrome carriers by measurement of the rate of reduction of the ergosterol C-7 double bond in cultured skin fibroblasts (1998) (8)
- Different feedback regulation of hepatic cholesterol and bile acid synthesis by glycodeoxycholic acid in rabbits. (1993) (8)
- Synthesis and intestinal metabolism of ursodeoxycholic acid conjugate with an antiinflammatory agent, 5-aminosalicylic acid. (1998) (8)
- Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. Commentary (2002) (7)
- Capillary gas-liquid chromatography of acetate-methyl esters of bile acids. (1997) (7)
- High-Performance Liquid Chromatography of Bile Acids Effect of Hydroxyl Groups at C-3, 6 7 and 12 on Bile Acid Mobility (1992) (7)
- Upregulation of hepatic cholesterol 27-hydroxy-lase (CYP27) activity and normal levels of hepatic cholesterol synthesis in cholesterol 7A-hydroxylase (cyp7A1) gene knockout mice (2000) (7)
- Stereospecific synthesis and two-dimensional 1H-NMR investigation of isoursocholic acid. (1991) (7)
- Improved synthesis of 5β-cholestan-26-oic acids (1979) (7)
- Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7alpha-hydroxylase in rabbits fed cholesterol. (2001) (7)
- FXR-mediated down-regulation of CYP7A1 dominates LXRα in long-term cholesterol-fed NZW rabbits Published, JLR Papers in Press, August 1, 2003. DOI 10.1194/jlr.M300182-JLR200 (2003) (7)
- Clinical perspective on the treatment of gallstones with ursodeoxycholic acid. (1988) (6)
- Bile acid flux through portal but not peripheral veins inhibits CYP7A1 expression without involvement of ileal FGF19 in rabbits. (2014) (6)
- Stereoselective synthesis of (24R and 24S) 5β-cholestane-3α,7α,12α,24,25-pentols and (25R and 25S) 5β-cholestane 3α,7α,12α,25,26-pentols using a modified osmium-catalyzed Sharpless asymmetric dihydroxylation process (1992) (6)
- Nonsurgical treatment of gallstones. (1989) (6)
- Pregnancy in women with cerebrotendinous xanthomatosis (CTX): high risk condition for fetus and newborn infant? (1988) (6)
- Cerebrotendinous xanthomatosis. (1989) (6)
- The stimulatory effect of LXRalpha is blocked by SHP despite the presence of a LXRalpha binding site in the rabbit CYP7A1 promoter. (2006) (6)
- Transformation of 4-cholesten-3-one and 7 alpha-hydroxy-4-cholesten-3-one into cholestanol and bile acids in cerebrotendinous xanthomatosis. (1984) (6)
- Synthesis of 5/3-cholestane-3~,71x,12~,25-tetrol and 5P-choIestane-3a,7a,I 2a,24&25-pentol (1976) (6)
- Preparation and characterization of (24R and 24S)-5μ-cholestane-3α, 7α,24,25-tetrols and (24R and 24S)-5β-cholestane-3α, 24, 25-triols (1978) (6)
- C26-analogs of naturally occurring bile alcohols-II. Preparation of 24-nor-5β-cholestane-3α,7α,12α,23-tetrols (23R and 23S) and 24-nor-5β-cholestane-3α,7α,12α,26-tetrols (25R and 25S) by a hydroboration procedure (1979) (6)
- Reverse cross-coupling in the synthesis 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid. (1979) (6)
- Configuration at C-25 in 3a,7a,12a-trihydroxy-5P- cholestan-26-oic acid by X-ray crystallography (1979) (6)
- In vivo incorporation of [2-14C]mevalonic acid into rat brain complex glycolipids: characterization of glycosylsterols in mammalian brain. (1994) (6)
- Diverticulosis of the small intestine (1969) (5)
- Abnormal cholesterol biosynthesis in sitosterolaemia and the Smith-Lemli-Opitz syndrome (1996) (5)
- Intrahepatic pigment and crystal forms in patients with cerebrotendinous xanthomatosis (CTX). (1978) (5)
- High serum and urinary unconjugated bile acid concentrations are associated with homozygous mutation in bile acid coenzyme A: Amino acid N-acyltransferase (BAAT) (2003) (5)
- Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome. (1996) (5)
- Chromatographic separation of putative precursors of cholestanol (1988) (5)
- Blocking late cholesterol biosynthesis inhibits the growth of transplanted Morris hepatomas (7288CTC) in rats (1996) (5)
- isolated from human bile (1983) (4)
- Improved synthesis of 3α,7α,12α,24ξ -tetrahydroxy-5 β -cholestan-26-oic acid (1982) (4)
- Chapter 52 – Cerebrotendinous Xanthomatosis (2015) (4)
- Synthesis of 3 alpha,7 alpha,12 alpha,25-tetrahydroxy-5 beta-cholestan-24-one, an intermediate in the 25-hydroxylation pathway of cholic acid biosynthesis from cholesterol. (1983) (4)
- Serial observations on the metabolism of peripheral acute leukemic leukocytes (1965) (4)
- Ursocholic acid, a hydrophilic bile acid, fails to improve liver function parameters in primary biliary cirrhosis: comparison with ursodeoxycholic acid. (1997) (4)
- Synthesis of 3α,7α-dihydroxy-5β-cholestan-26-oic acid from 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid: configuration in the bile of Alligator mississippiensis (1992) (4)
- UvA-DARE ( Digital Academic Repository ) A mouse model of sitosterolemia : absence of Abcg 8 / sterolin-2 results in failure to secrete biliary cholesterol (2004) (4)
- Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits. (2001) (4)
- Abnormal cholesterol metabolism in the Smith-Lemli-Opitz syndrome (1997) (4)
- Circular dichroism studies of keto-bile acids (1980) (3)
- A study on biliary ductal system and bile fistula in the American alligator, Alligator mississippiensis. (1997) (3)
- Biosynthesis of chenodeoxycholic acid: Side-chain hydroxylation of 5β-cholestane-3α,7α-diol by subcellular fractions of guinea pig liver (1978) (3)
- Structure and biosynthesis of bile alcohols: disorders of cholesterol side-chain oxidation in cerebrotendinous xanthomatosis (1995) (3)
- Abnormal cholesterol biosynthesis produced by AY 9944 in the rat leads to skeletal deformities similar to the Smith-Lemli-Opitz syndrome. (1998) (3)
- Gallstone dissolution therapy with ursodiol. Efficacy and safety. (1989) (3)
- Erratum: Ursodeoxycholic acid for the treatment of primary sclerosing cholangitis: A 30-month pilot study (Hepatology (November 1991) 14 (838-847)) (1992) (3)
- Identification of 5 β-cholestane-3 α, 7 α, 12 α, 25, 26-pentol in cerebrotendinous xanthomatosis (1983) (3)
- Synthesis and structure of 26 (or 27)-nor-5fl- cholestane-3~,7~,12a,24S,25~-pentol isolated from the urine and feces of a patient with sitosterolemia and xanthomatosis' (1985) (3)
- Extracorporeal lithotripsy of gall-bladder stones: Results, cost-effectiveness, future perspectives (1989) (3)
- Anomalous enantioselectivity in the sharpless asymmetric dihydroxylation reaction of 24-nor-5β-cholest-23-ene-3α,7α,12α-triol: Synthesis of substrates for studies of cholesterol side-chain oxidation (1999) (3)
- A facile synthesis of 5β-cholestane-3α, 7α, 12α,25-tetrol (1980) (3)
- Microwave-Induced Rapid Synthesis of Sarcosine Conjugated Bile Acids. (1995) (3)
- The Diagnosis and Treatment of Cerebrotendinous Xanthomatosis (2017) (2)
- High-performance liquid chromatographic separation of bile acids and bile alcohols diastereoisomeric at C-25. (1991) (2)
- Cholestanol Deposition in Cerebrotendinous Xanthomatosis (2020) (2)
- OBSERVATIONS OF THE METABOLISM OF PERIPHERAL LEUKOCYTES IN ACUTE LEUKEMIA: II. URIDINE AND PHENYLALANINE INCORPORATION (1965) (2)
- Decreased ilead bile acid reabsorption lowered plasma cholesterol levels by reducing hepatic FXR activation to stimulate CYP7A1 (2003) (2)
- A facile synthesis of [3 alpha-3 H]beta -sitosterol. (1983) (2)
- Nuclear Receptors Regulate Bile Acid Synthesis (2009) (2)
- Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in the rat ileum: effects of bile acids and lovastatin. (1994) (2)
- Characterization of sarcosylsarcoursodeoxycholic acid formed during the synthesis of sarcoursodeoxycholic acid. (1989) (2)
- Synthesis of biological precursors of cholic acid II (1981) (2)
- Comparative effects of high and low dose ursodeoxycholic acid on gallstone dissolution and biliary lipid composition (1978) (2)
- A convenient synthesis of dinorbile acids: Oxidative hydrolysis of norbile acid nitriles☆ (1999) (2)
- Lipid Profiles in Smith-Lemli-Opitz Syndrome (SLOS). † 347 (1997) (1)
- Synthesis of 3a,7a,12ar,25-tetrahydroxy-5fl- cholestan-24sne, an intermediate in the 25- hydroxylation pathway of cholic acid biosynthesis from cholesterol (1983) (1)
- Inhibition of cholesterol biosynthesis by chenodeoxycholic acid in the rhesus monkey. (1975) (1)
- Synthesis of the putative metabolites of plant sterols: (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol. (1984) (1)
- Asymmetric Syntheses and Lanthanide‐Induced CD Studies of (24R and 24S) 5β‐Cholestane‐3α,7α,12α,24,25‐pentols. (1995) (1)
- Bile alcohol glucuronides: regioselective O-glucuronidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol and 24-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol. (1993) (1)
- Synthesis of 3 alpha,6 beta,7 alpha,12 beta- and 3 alpha,6 beta,7 beta,12 beta-tetrahydroxy-5 beta-cholanoic acids. (1992) (1)
- Campestanol (24-methyl-5alpha-cholestan-3beta-ol) absorption and distribution in New Zealand White rabbits: effect of dietary sitostanol. (1999) (1)
- Microwave-Induced Rapid Synthesis of Bile Acid Conjugates. (1996) (1)
- Effect of ursodiol on bile acid conjugation in patients with primary biliary cirrhosis (1990) (1)
- Antenatal Therapy of Smith-Lemli-Opitz Syndrome ♦ 719 (1998) (1)
- C,,-Analogs of naturally occurring C,, bile alcohols (1976) (1)
- IN THE BIOSYNTHESIS OF CHENODEOXYCHOLIC ACID (1979) (1)
- A facile synthesis of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol. (1980) (1)
- Abnormal hepatic bile acid transport is not improved by ursodiol in benign recurrent intrahepatic cholestasis (BRIC) (2001) (0)
- Improved synthesis of 3 alpha, 7 alpha, 12 alpha, 24 = xi-tetrahydroxy-5 beta-cholestan-26-oic acid. (1982) (0)
- 7 OC Weight loss obtained by the biliary-intestinal bypass, but not that obtained by the gastric binding, is associated with a strong hypocholesterolemic effect (2002) (0)
- Synthesis of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid from 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid: configuration in the bile of Alligator mississippiensis. (1992) (0)
- Helicobacter Species Identified in Liver From Patients With Cholangiocarcinoma and Hepatocellular Carcinoma (2001) (0)
- Cholic acid biosynthesis: conversion of 5p-choles- tan e-3a, 7a, 1 2a ,25-tet ro I i n to 5p-c h o I estan e- 3a,7a,l2a,24p,25=pentol by human and rat liver microsomes (1977) (0)
- Dietary campestanol is poorly absorbed and does not accumulate when fed to rabbits (1998) (0)
- Contents, Vol. 37, 1967 (1967) (0)
- More hydrophilic bacterial bile acid metabolites are concentrated in the aqueous phase of human stool (2000) (0)
- Preparation and characterization of (24R and 24S)-5beta-cholestane-3alpha,7alpha,24,25-tetrols and (24R and 24S)-5beta-cholestane-3alpha,24,25-triols. (1978) (0)
- Comparative effect of a low sterol diet on cholesterol and bile acid synthesis in a sitosterolemic homozygote and a heterozygote subject (1994) (0)
- Stereoselective synthesis of (24R and 24S) 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25-pentols and (25R and 25S) 5 beta-cholestane-3 alpha,7 alpha,12 alpha,25,26-pentols using a modified osmium-catalyzed Sharpless asymmetric dihydroxylation process. (1992) (0)
- Improved weight gain following closure of exteriorized conduit for biliary atresia (1990) (0)
- Identification of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 25, 26-pentol in cerebrotendinous xanthomatosis. (1983) (0)
- Treatment with 600 mg/day of ursodeoxycholic acid maximally supresses the proportion of deoxcholic acid in fecal water (1998) (0)
- Measurement of 3 p-hydroxysteroid A 7-reductase activity in cultured skin fibroblasts utilizing ergosterol as a substrate : a new method for the diagnosis of the Smith (0)
- Synthesis of Steroidal Pyrimidines. (1996) (0)
- Is Splenic Injury From Colonoscopy Malpractice? Authors' reply (2010) (0)
- An improved method for the isolation, quantitation, and identification of bile acids in rats feces. (1975) (0)
- EFFICACY AND SAFETY OF ADDING EZETIMIBE 30 MILLIGRAMS TO A BACKGROUNG OF EZETIMIBE 10 MILLIGRAMS IN PATIENTS WITH HOMOZYGOUS SITOSTEROLEMIA (2008) (0)
- Increasing the ursodeoxycholate (UDC): deoxycholate (DCA) ratio in model fecal water solutions enhances apoptosis of colon cancer cells. Possible mechanism for cancer chemoprevention effect of UDC (2000) (0)
- T1919 The Effect of Colesevelam HCL on Glycemic Control in Insulin Resistant Rat Model (2010) (0)
- Ketoconazole normalized hepatic levels of intermediates in bile acid biosynthesis in Cyp27-/- mice (2003) (0)
- Biosynthesis of chenodeoxycholic acid: side-chain hydroxylation of 5 beta-cholestane-3 alpha, 7 alpha-diol by subcellular fractions of guinea pig liver. (1978) (0)
- A Rare Disease With Diverse Manifestations (2016) (0)
- Response to Dr Rex (2010) (0)
- Index rerum ad Vol. 37 (1967) (0)
- Identification of 3β-hydroxy-5-cholesten-26,27-dicarboxylic acid, a novel product formed when cholesterol is incubated with human mononuclear leukocytes (1998) (0)
- Studies on the 12α and 26-hydroxylation of bile alcohols by rabbit liver microsomes (1976) (0)
- Reverse cross-coupling in the synthesis of 3a, 7a-d i hyd roxy-5P-c ho lestano ic acid (1979) (0)
- List of contributors. (2019) (0)
- Improved method for the determination of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine in tissue using high-performance liquid chromatography with electrochemical detection. (1992) (0)
- 6972 Prevalence of rectal cancers at veterans affairs new jersey health care system (vanjhcs). (2000) (0)
- Malabsorption in Intestinal Scleroderma (2020) (0)
- Preparation of [3beta-3H] labeled bile acids and bile alcohols. (1979) (0)
- The importance of side chain conjugation on the feedback regulation on bile acid synthesis in the rabbit (1992) (0)
- Configurational assignment of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 23, 25-pentol excreted by patients with cerebrotendinous xanthomatosis (a circular dichroism study). (1979) (0)
- The feedback regulation of cholesterol and bile acid synthesis by dietary cholesterol is independently expressed in rabbits (1998) (0)
- The neuropsychology of Cerebrotendinous Xanthomatosis: A rare progressive dementia syndrome (1999) (0)
- M1723 Highly Sensitive Metabolome Analysis of Cholesterol and Bile Acid Biosynthetic Pathways By LC-ESI-MS/MS (2009) (0)
- Mo1145 Regulation of CYP7A1: by Bile Acid or FGF15/19? (2012) (0)
- Metabolism of leukocytes in a case of acute leukemia. (1967) (0)
- CYP7A1 is inhibited by activated FXR via SHP and LRH-1 in cholesterol-fed rabbits (2001) (0)
- FXR is the dominant regulator of CYP7A1 in the rat (2003) (0)
- Studies on the 12alpha and 26-hydroxylation of bile alcohols by rabbit liver microsomes. (1976) (0)
- Regulation of rat hepatic 3β-hydroxysterol Δ7-reductase activity (1998) (0)
- Improved synthesis of 5 beta-cholestan-26-oic acids. (1979) (0)
- Identification of pentahydroxy bile alcohols in cere b ro t endi no us xanthomatosis : c ha rac t er i za t io n of (1975) (0)
- BILE ACIDS | Gas Chromatography (2000) (0)
- Portal bile acid perfusion bypasses ileal FGF19 and suppresses hepatic CYP7A1 expression in rabbits (605.6) (2014) (0)
- Index autorum ad Vol. 37 (1967) (0)
- CORRELATION OF CLINICAL PHENOTYPE AND BIOCHEMICAL DEFECT IN SMITH-LEMLI-OPITZ SYNDROME (SLOS). • 480 (1996) (0)
- Medical therapy for cholesterol-gallstones: A role of statins? (1999) (0)
- Letter: Toxicity of chenodeoxycholic acid in rhesus monkeys. (1974) (0)
- Abnormal cholesterol biosynthesis in the Smith = Lem I i-0 pi tz sy nd rome (1996) (0)
- Sitosterolemia; of mice and man (2004) (0)
- 7 beta-hydroxy bile alcohols: facile synthesis and 2D 1H NMR studies of 5 beta-cholestane-3 alpha, 7 beta, 12 alpha, 25-tetrol. (1997) (0)
- Anomalous enantioselectivity in the sharpless asymmetric dihydroxylation reaction of 24-nor-5beta-cholest-23-ene-3alpha,7alpha,12alpha-triol: synthesis of substrates for studies of cholesterol side-chain oxidation. (1999) (0)
- The Natural History of Phytosterolemia: Observations on its Homeostasis (2018) (0)
- C26-analogs of naturally occurring bile alcohols-II. Preparation of 24-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,23-tetrols (23R and 23S) and 24-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,26-tetrols (25R and 25S) by a hydroboration procedure. (1979) (0)
- ldentif ication of 8-de hydroc holesterol (c holesta-5,8-d ien-30 -01) i n patients with S m it h- Lem I i-0 p i t z syndrome (1995) (0)
- Immunohistochemical evaluation of mouse Abcg5/sterolin-1 expression in liver and intestine (2011) (0)
- A highly simplified method for plasma and fecal bile acid analysis in humans (1998) (0)
- Regulation of cholesterol 7A-hydroxylase by orphan nuclear receptors in cholesterol-fed and bile fistula rabbits (2000) (0)
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