Gilbert Vassart

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Gilbert Vassart is affiliated with the following schools: Université libre de Bruxelles, University of Cagliari, University of Turku

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Gilbert Vassart

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#4281

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#6748

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#1781

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#2620

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Gilbert Vassart

Biology

#5577

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#8090

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Immunology

#273

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#284

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Molecular Biology

#507

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#518

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Genetics

#508

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#583

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biology Degrees

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Philosophy
Biology

Gilbert Vassart's Degrees

PhD Molecular Biology Université libre de Bruxelles
Doctorate Medicine Université libre de Bruxelles

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Gilbert Vassart's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene (1996) (2991)
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor (1995) (1817)
The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54* (2001) (1391)
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. (1999) (1323)
Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation* (2003) (1253)
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor (1997) (922)
ORL1, a novel member of the opioid receptor family (1994) (920)
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas (1993) (878)
Specific Recruitment of Antigen-presenting Cells by Chemerin, a Novel Processed Ligand from Human Inflammatory Fluids (2003) (831)
Molecular cloning and functional expression of a new human CC-chemokine receptor gene. (1996) (709)
Molecular cloning of a human cannabinoid receptor which is also expressed in testis. (1991) (684)
The thyrotropin receptor and the regulation of thyrocyte function and growth. (1992) (634)
Cloning of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family* (2000) (624)
Selective amplification and cloning of four new members of the G protein-coupled receptor family. (1989) (621)
A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA. (1987) (563)
Molecular cloning of the thyrotropin receptor. (1989) (486)
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies. (1989) (399)
Expression of members of the putative olfactory receptor gene family in mammalian germ cells (1992) (363)
Germline mutations in the thyrotropin receptor gene cause non–autoimmune autosomal dominant hyperthyroidism (1994) (352)
Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity (1996) (324)
A molecular dissection of the glycoprotein hormone receptors. (2004) (324)
Non-peptide arginine-vasopressin antagonists: the vaptans (2008) (317)
Control of Thyroglobulin Synthesis and Secretion (1979) (301)
Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. (1995) (289)
Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. (1998) (283)
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity (2005) (280)
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. (1998) (280)
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. (1999) (278)
Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease. (1999) (277)
DNA fingerprinting in domestic animals using four different minisatellite probes. (1988) (269)
RDC8 codes for an adenosine A2 receptor with physiological constitutive activity. (1990) (269)
Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor. (2003) (259)
ChemR23, a putative chemoattractant receptor, is expressed in monocyte‐derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV‐1 strains (1998) (259)
Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. (1996) (253)
Neutrophil-Mediated Maturation of Chemerin: A Link between Innate and Adaptive Immunity1 (2005) (253)
Somatic and germline mutations of the TSH receptor gene in thyroid diseases. (1995) (252)
Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland. (1997) (247)
Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas. (1997) (240)
Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades. (1995) (238)
Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA (1985) (230)
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. (1995) (222)
POLYMORPHIC DNA MARKER ON X CHROMOSOME AND MANIC DEPRESSION (1987) (215)
Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues. (1994) (209)
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation (1997) (207)
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor. (1998) (206)
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors (2002) (200)
Control of thyroglobulin synthesis and secretion. (First of two parts). (1979) (197)
Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers (2005) (197)
Glycoprotein hormone receptors: determinants in leucine‐rich repeats responsible for ligand specificity (2003) (194)
The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity* (1997) (193)
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor. (1991) (190)
Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter. (1992) (189)
Distribution of adenosine A2 receptor mRNA in the human brain (1991) (187)
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. (2002) (184)
Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. (2013) (175)
Thyroperoxidase, an auto‐antigen with a mosaic structure made of nuclear and mitochondrial gene modules. (1987) (170)
The C-terminal Nonapeptide of Mature Chemerin Activates the Chemerin Receptor with Low Nanomolar Potency* (2004) (170)
Olfactory receptors are displayed on dog mature sperm cells (1993) (170)
Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8. (2001) (169)
Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptor (1990) (168)
The Core Domain of Chemokines Binds CCR5 Extracellular Domains while Their Amino Terminus Interacts with the Transmembrane Helix Bundle* (2003) (168)
A 3' splice site mutation in the thyroglobulin gene responsible for congenital goiter with hypothyroidism. (1991) (162)
Multiple Charged and Aromatic Residues in CCR5 Amino-terminal Domain Are Involved in High Affinity Binding of Both Chemokines and HIV-1 Env Protein* (1999) (160)
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones. (1990) (156)
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. (2000) (154)
Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities? (1998) (154)
Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology. (2002) (153)
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. (2002) (151)
Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism. (1992) (150)
Human thyrotropin receptor gene: Expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation (1991) (149)
G protein-coupled receptors: mutations and endocrine diseases (2011) (146)
Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree. (2007) (146)
Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2 (2005) (146)
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia. (1996) (144)
Palmitoylation of CCR5 Is Critical for Receptor Trafficking and Efficient Activation of Intracellular Signaling Pathways* (2001) (144)
Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology. (2006) (144)
Allosteric Modulation of Binding Properties between Units of Chemokine Receptor Homo- and Hetero-Oligomers (2006) (142)
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome. (2004) (140)
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid. (1994) (138)
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N‐terminal extracellular domain (1997) (135)
Nucleotide sequence of a human cannabinoid receptor cDNA. (1990) (133)
Premature ovarian aging in mice deficient for Gpr3. (2005) (133)
LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. (2009) (132)
Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism. (2004) (130)
Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (1997) (130)
The TXP Motif in the Second Transmembrane Helix of CCR5 (2001) (129)
Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties (2000) (129)
Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells. (1977) (127)
An Activation Switch in the Rhodopsin Family of G Protein-coupled Receptors (2005) (126)
Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity* (1999) (125)
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2 (2005) (124)
Defective postnatal development of the male reproductive tract in LGR4 knockout mice. (2006) (123)
Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene. (1992) (122)
Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. (2004) (122)
Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo (2011) (121)
Development of an animal model of autoimmune thyroid eye disease. (1999) (119)
The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3. (1996) (117)
Multiple nonfunctional alleles of CCR5 are frequent in various human populations. (2000) (115)
Functional characterization of a human receptor for neuropeptide FF and related peptides (2001) (114)
Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. (1995) (112)
Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells. (1985) (111)
A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts. (1987) (110)
A Conserved Asn in Transmembrane Helix 7 Is an On/Off Switch in the Activation of the Thyrotropin Receptor* (2001) (110)
Somatic and germline mutations of the TSH receptor and thyroid diseases (2001) (110)
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. (2008) (109)
Cloning and functional characterization of a human A1 adenosine receptor. (1992) (109)
Molecular cloning, functional expression and pharmacological characterization of a mouse melanocortin receptor gene. (1994) (105)
Follitropin receptor down-regulation involves a cAMP-dependent post-transcriptional decrease of receptor mRNA expression (1991) (103)
Mutation of the DRY Motif Reveals Different Structural Requirements for the CC Chemokine Receptor 5-Mediated Signaling and Receptor Endocytosis (2005) (103)
CCR5 and HIV infection. (2002) (102)
Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor. (1993) (94)
Control of thyroperoxidase and thyroglobulin transcription by cAMP: evidence for distinct regulatory mechanisms. (1989) (93)
Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy (1995) (93)
Analysis of sequence and structure homologies between thyroglobulin and acetylcholinesterase: possible functional and clinical significance. (1986) (92)
Thyrotropin controls transcription of the thyroglobulin gene. (1984) (90)
On the use of DNA fingerprints for linkage studies in cattle. (1990) (87)
An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene. (1985) (87)
Allosteric properties of G protein-coupled receptor oligomers. (2007) (87)
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger. (1993) (86)
Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse (2005) (86)
New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome? (2004) (85)
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors (1996) (85)
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. (2005) (84)
The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. (1999) (83)
Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA. (1987) (82)
Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor. (2004) (81)
Defective thyroglobulin synthesis and secretion causing goiter and hypothyroidism. (1993) (81)
A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons. Possible relationship with D1 dopamine receptor (1990) (81)
Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector. (1991) (79)
Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues. (1994) (78)
Specificity and promiscuity of gonadotropin receptors. (2005) (78)
TSH receptor and disease (1996) (78)
Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications. (1987) (77)
Specific activation of the thyrotropin receptor by trypsin (1996) (77)
Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene. (2009) (77)
Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas. (2001) (77)
Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease. (1991) (76)
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH. (1997) (76)
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues. (2006) (76)
Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies (1990) (75)
Genotypic and gene expression studies in congenital melanocytic nevi: insight into initial steps of melanotumorigenesis. (2009) (74)
Production of bioactive amino‐terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor (1998) (73)
Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein. (1992) (73)
The thyrotropin receptor in thyroid eye disease. (1998) (72)
Variants of the BMP15 gene in a cohort of patients with premature ovarian failure. (2010) (72)
Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system (1999) (72)
Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters. (2000) (71)
Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi. (2007) (70)
Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor. (1991) (70)
TSH Receptor Mutations and Thyroid Disease (1998) (69)
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity. (2002) (69)
Differentiation expression during proliferative activity induced through different pathways: in situ hybridization study of thyroglobulin gene expression in thyroid epithelial cells (1990) (68)
Complete nucleotide sequence of a putative G protein coupled receptor: RDC1. (1990) (67)
Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution. (1987) (67)
In vitro and in vivo regulation of thyrotropin receptor mRNA levels in dog and human thyroid cells. (1992) (67)
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. (2001) (66)
A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family. (1999) (66)
Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors. (2005) (66)
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. (2004) (65)
Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG. (2002) (64)
Thyroid dysgenesis: multigenic or epigenetic ... or both? (2005) (64)
GPR3 Receptor, a Novel Actor in the Emotional-Like Responses (2009) (64)
Possible non-Mendelian mechanisms of thyroid dysgenesis. (2007) (64)
In Chinese hamster ovary K1 cells dog and human thyrotropin receptors activate both the cyclic AMP and the phosphatidylinositol 4,5-bisphosphate cascades in the presence of thyrotropin and the cyclic AMP cascade in its absence. (1995) (62)
Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice. (1991) (61)
The human thyroglobulin gene contains two 15-17 kb introns near its 3'-end. (1983) (61)
A polymorphic satellite sequence maps to the pericentric region of the bovine Y chromosome. (1989) (61)
Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene. (1997) (61)
Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model. (1994) (60)
Genomic organization of the human thyroglobulin gene: the complete intron-exon structure. (2001) (58)
Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): measurement of denatured TBG in serum. (1984) (58)
Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor (1996) (57)
Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands. (2008) (57)
Transcriptional regulation of the thyroperoxydase gene by thyrotropin and forskolin (1988) (56)
Hyperfunctioning malignant thyroid nodule in an 11-year-old girl: pathologic and molecular studies. (2000) (56)
GRIS: glycoprotein-hormone receptor information system. (2006) (56)
Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome (2000) (56)
Transcriptional control of thyroglobulin gene expression by cyclic AMP (1985) (55)
Localization of human thyrotropin receptor gene to chromosome region 14q3 by in situ hybridization. (1990) (55)
Translational control of protein synthesis: a simulation study. (1971) (54)
Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension. (2003) (54)
Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability. (1992) (54)
Defective thyroglobulin synthesis and secretion causing goiter and hypothyroidism (1993) (53)
Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. (1997) (53)
Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene. (2000) (52)
Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome (2008) (52)
Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins. (1994) (52)
Ontogeny, Anatomy, Metabolism and Physiology of the Thyroid (2015) (52)
The human pregnancy-specific β1-glycoprotein (PSβG) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family (1988) (51)
Current developments in G-protein-coupled receptors. (1991) (51)
Pax 8 expression in primary cultured dog thyrocyte is increased by cyclic AMP. (1996) (50)
Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant1 (2001) (50)
The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10 (2005) (50)
A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis. (1999) (49)
Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor. (2001) (49)
A familial case of congenital hypothyroidism caused by a homozygous mutation of the thyrotropin receptor gene. (2001) (49)
Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope. (1989) (49)
Clinical review 84: Thyroid autonomy: mechanism and clinical effects. (1996) (49)
Specific ablation of thyroid follicle cells in adult transgenic mice. (1991) (49)
The orphan receptor cDNA RDC4 encodes a 5-HT1D serotonin receptor. (1991) (48)
The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids. (1979) (48)
Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands (2010) (47)
The specificity of binding of glycoprotein hormones to their receptors (2008) (46)
Synthesis of a full length DNA complementary to thyroglobulin 33 S messenger RNA. (1980) (46)
Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin (1993) (44)
Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice. (1996) (44)
Abnormal cellular localization of thyroglobulin mRNA associated with hereditary congenital goiter and thyroglobulin deficiency. (1978) (43)
Understanding ovarian hyperstimulation syndrome (2005) (43)
Cloning and sequencing of a calcium‐binding protein regulated by cyclic AMP in the thyroid. (1989) (43)
Identification of a cAMP-responsive region in thyroglobulin gene promoter (1989) (43)
Cloning of human thyroglobulin complementary DNA (1982) (42)
Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA. (2003) (41)
Thyroid autonomy : Mechanism and clinical effects (1996) (41)
DNA fingerprinting in man using a mouse probe related to part of the Drosophila 'Per' gene. (1987) (40)
The TSH receptor and thyroid diseases. (1996) (40)
Activating mutations of TSH receptor. (2004) (39)
Studies with recombinant autoepitopes of thyroid peroxidase: evidence suggesting an epitope shared between the thyroid and the gastric parietal cell. (1990) (39)
Early occurrence of metastatic differentiated thyroid carcinomas in transgenic mice expressing the A2a adenosine receptor gene and the human papillomavirus type 16 E7 oncogene. (1996) (39)
Translation of thyroglobulin 33S messenger RNA as a means of determining thyroglobulin quaternary structure. (1975) (39)
Structure-function relationships of two loss-of-function mutations of the thyrotropin receptor gene. (1999) (38)
Thyroglobulin messenger RNA: translation of a 33-S mRNA into a peptide immunologically related to thyroglobulin. (1975) (38)
HOMOLOGY BETWEEN THYROGLOBULIN AND ACETYLCHOLINESTERASE: AN EXPLANATION FOR PATHOGENESIS OF GRAVES' OPHTHALMOPATHY? (1986) (38)
Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage (2016) (38)
Study of TTF-1 gene expression in dog thyrocytes in primary culture (1995) (37)
Differentiated carcinomas develop as a consequence of the thyroid specific expression of a thyroglobulin-human papillomavirus type 16 E7 transgene. (1995) (37)
Functional study of the human thyroid peroxidase gene promoter. (1992) (37)
Pathology of the TSH receptor. (1999) (37)
Evolutionary conservation of bursicon in the animal kingdom. (2007) (37)
Defective splicing of thyroglobulin gene transcripts in the congenital goitre of the Afrikander cattle. (1985) (37)
Definition, at the molecular level, of a thyroglobulin-acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy. (1989) (36)
Specific synthesis of thyroglobulin on membrane bound thyroid ribosomes (1972) (36)
Towards an antigenic map of human thyroglobulin: identification of ten epitope-bearing sequences within the primary structure of thyroglobulin. (1989) (36)
Thyroid stimulating immunoglobulins, like thyrotropin activate both the cyclic AMP and the PIP2 cascades in CHO cells expressing the TSH receptor (1992) (36)
Identification of polysomes synthesizing thyroglobulin. (1973) (36)
Lack of evidence supporting the presence of mRNA for the thyrotropin receptor in extra-ocular muscle (1993) (35)
Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+-levels in Drosophila S2 cells (2002) (35)
Molecular weight of thyroglobulin 33 S messenger RNA as determined by polyacrylamide gel electrophoresis in the presence of formamide (1977) (35)
Control of thyroglobulin synthesis and secretion (second of two parts). (1979) (35)
Long-Term Follow-Up of an Infant with Thyrotoxicosis due to Germline Mutation of the TSH Receptor Gene (Met453Thr) (1999) (35)
Thyroid peroxidase gene promoter confers TSH responsiveness to heterologous reporter genes in transfection experiments. (1990) (34)
Structural organization of the bovine thyroglobulin gene and of its 5'-flanking region. (1987) (34)
A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist (2002) (34)
Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers (2012) (34)
Structure, expression and regulation of the thyroglobulin gene (1985) (33)
Structural organization of the 5' region of the human thyroglobulin gene. (1984) (33)
Mapping thyroid peroxidase epitopes using recombinant protein fragments. (1995) (33)
Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice. (1990) (33)
The autoimmune response induced by immunising female mice with recombinant human thyrotropin receptor varies with the genetic background (1995) (33)
The molecular genetics of three thyroid autoantigens: thyroglobulin, thyroid peroxidase and the thyrotropin receptor. (1990) (33)
Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies. (2008) (32)
Genomic organization of the 3' region of the human thyroglobulin gene. (2000) (32)
Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12. (1988) (32)
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R. (1994) (32)
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor. (1996) (31)
The human calbindin 27-kDa gene: structural organization of the 5' and 3' regions, chromosomal assignment, and restriction fragment length polymorphism. (1989) (31)
Ectopic thyroid gland causing dysphonia: imaging and molecular studies. (2010) (31)
Rarity of anti- Na+/I- symporter (NIS) antibody with iodide uptake inhibiting activity in autoimmune thyroid diseases (AITD). (2000) (31)
A family with a novel TSH receptor activating germline mutation (p.Ala485Val) (2008) (31)
Single-nucleotide polymorphism genotyping by melting analysis of dual-labeled probes: examples using factor V Leiden and prothrombin 20210A mutations. (2003) (31)
Enhancement of cmyc mRNA concentration in dog thyrocytes initiating DNA synthesis in response to thyrotropin, forskolin, epidermal growth factor and phorbol myristate ester. (1986) (31)
Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population. (2002) (31)
Constitutively active receptors as a disease-causing mechanism (1994) (30)
Molecular cloning of a dog thyrotropin (TSH) receptor variant (1990) (30)
Radioautographic localization of prolactin messenger RNA on histological sections by in situ hybridization (1981) (30)
The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3----q22.1 and 16q22----q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci. (1991) (30)
Functional role of TTF‐1 binding sites in bovine thyroglobulin promoter (1992) (30)
Identification of a thyroid-specific and cAMP-responsive enhancer in the upstream sequences of the human thyroglobulin promoter. (1996) (30)
Molecular cloning of the 8000-base thyroglobulin structural gene. (2005) (29)
A physiological role for the posttranslational cleavage of the thyrotropin receptor? (2004) (29)
Incidence of chromosomal mosaicism in human embryos at different developmental stages analyzed by fluorescence in situ hybridization. (2003) (29)
RDC1 may not be VIP receptor. (1992) (29)
Genomic organization of the 5' region of the human thyroglobulin gene. (1999) (28)
Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci. (2005) (28)
Dopaminergic control of prolactin mRNA accumulation in the pituitary of the male rat (1981) (27)
Demonstration of the existence of the alternatively spliced form of thyroid peroxidase in normal thyroid. (1991) (27)
Comparison of primary and secondary stimulation of male rats by estradiol in terms of prolactin synthesis and mRNA accumulation in the pituitary. (1979) (27)
Alternative splicing may be responsible for heterogeneity of thyroglobulin structure. (1989) (27)
The human and dog 5-HT1D receptors can both activate and inhibit adenylate cyclase in transfected cells. (1993) (26)
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors. (1998) (26)
Evidence for the segregation of three different mutated alleles of the thyroglobulin gene in a Brazilian family with congenital goiter and hypothyroidism. (1998) (26)
Translation in Xenopus oocytes of thyroglobulin mRNA isolated by poly(U)-Sepharose affinity chromatography. (1973) (26)
Lack of minocycline efficiency in genetic models of Huntington’s disease (2007) (26)
Improved synthesis of DBM paper. (1982) (26)
The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases. (1995) (25)
Molecular genetics of the thyrotropin receptor (1991) (25)
Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1 (2005) (25)
Thyroid autonomy: mechanism and clinical effects: clinical review 84 (1996) (24)
Costimulation of Adenylyl Cyclase and Phospholipase C by a Mutantα 1B-Adrenergic Receptor Transgene Promotes Malignant Transformation of Thyroid Follicular Cells1. (1997) (23)
The high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptor. (1993) (23)
Analysis of C-terminally substituted tachykinin-like peptide agonists by means of aequorin-based luminescent assays for human and insect neurokinin receptors. (2002) (23)
The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. (1990) (23)
Linkage relationships among 20 genetic markers in cattle. Evidence for linkage between two pairs of blood group systems: B-Z and S-F/V respectively. (1990) (23)
cAMP-dependent binding of a trans-acting factor to the thyroglobulin promoter. (1989) (22)
New pathophysiological mechanisms for hyperthyroidism. (1997) (22)
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1 glycoprotein gene family. (1990) (22)
Transgenic models for proliferative and hyperfunctional thyroid diseases. (2009) (22)
Absence of human chorionic somatomammotropin during pregnancy associated with two types of gene deletion (1986) (22)
Leydig cell tumors in children: contrasting clinical, hormonal, anatomical, and molecular characteristics in boys and girls. (2012) (21)
Identification of a minor Tg mRNA transcript in RNA from normal and goitrous thyroids (1992) (21)
Three‐Dimensional Reconstruction of Efferent Ducts in Wild‐Type and Lgr4 Knock‐Out Mice (2009) (21)
Control of growth and differentiation by known intracellular signal molecules in endocrine tissues: the example of the thyroid gland. (1984) (21)
Thyrotropin-stimulated recruitment of free monoribosomes on to membrane-bound thyroglobulin-synthesizing polyribosomes. (1978) (21)
Restriction mapping of synthetic thyroglobulin structural gene as a means of investigating thyroglobulin structure. (1980) (21)
Human, bovine, canine and rat thyroglobulin promoter sequences display species-specific differences in an in vitro study (1993) (21)
Probing the cause of thyroid dysgenesis. (1997) (20)
The thyroglobulin gene resides on chromosome 8 in man and on chromosome 7 in the rat. (1985) (20)
Analysis of genetic variation in the Belgian Blue cattle breed using DNA sequence polymorphism at the growth hormone, low density lipoprotein receptor, alpha-subunit of glycoprotein hormones and thyroglobulin loci. (2009) (19)
Cloning and sequence analysis of TFE, a helix-loop-helix transcription factor able to recognize the thyroglobulin gene promoter in vitro. (1991) (19)
Identification of a transcriptional enhancer upstream from the bovine thyroglobulin gene (1992) (19)
LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea (2016) (19)
The G Protein–coupled Receptor Family and One of Its Members, the TSH Receptor a (1995) (19)
Functional characteristics of a variant thyrotropin receptor. (1996) (19)
The 5′‐end of bovine thyroglobulin mRNA encodes a hormonogenic peptide (1982) (19)
Physical mapping of the CC-chemokine gene cluster on the human 17q11. 2 region. (1999) (19)
LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling (2020) (19)
Autonomous Adenomas Caused by Somatic Mutations of the Thyroid-Stimulating Hormone Receptor in Children (2014) (18)
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor (2004) (18)
Molecular cloning of Pst I fragments from rat double stranded thyroglobulin complementary DNA. (1980) (18)
Expression of human pregnancy specific beta 1 glycoprotein (PSG) genes during placental development. (1990) (18)
Presence of 2'–5' a synthetase in dog liver (1981) (17)
Re‐analysis by fluorescence in situ hybridisation of spare embryos cultured until Day 5 after preimplantation genetic diagnosis for a 47, XYY infertile patient demonstrates a high incidence of diploid mosaic embryos: a case report (2000) (17)
Proximity of thyroglobulin and c-myc genes on human chromosome 8 (1985) (17)
Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine. (1997) (17)
Muscle autoantigens in thyroid associated ophthalmopathy: The limits of molecular genetics (1993) (17)
Thyroperoxidase mRNA in quiescent and proliferating thyroid epithelial cells: expression and subcellular localization studied by in situ hybridization. (1993) (16)
Oncogenic mutations in thyroid adenoma: methodological criteria. (1996) (16)
Simulation of polyribosome disaggregation. (1970) (16)
Molecular genetics of thyroid diseases. (1994) (16)
Western blot analysis of thyrotropin receptor expression in human thyroid tumours and correlation with TSH-binding. (1994) (16)
LGR5 controls extracellular matrix production by stem cells in the developing intestine (2019) (15)
Reverse transcription of thyroglobulin 33-S mRNA. (1977) (15)
Genetic variation of the bovine thyroglobulin gene studied at the DNA level. (2009) (15)
Isolation and characterization of the canine thyroglobulin gene promoter region. (1991) (15)
Presence of hormonogenic and repetitive domains in the first 930 amino acids of bovine thyroglobulin as deduced from the cDNA sequence. (1985) (15)
Chimeraplasty validation (2001) (15)
The thyroperoxidase doublet is not produced by alternative splicing (1995) (15)
A zinc-dependent DNA-binding activity co-operates with cAMP-responsive-element-binding protein to activate the human thyroglobulin enhancer. (1997) (15)
Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells. (1997) (14)
Thyroid-specific and cAMP-dependent hypersensitive regions in thyroglobulin gene chromatin. (1988) (14)
The OLFR1 gene encoding the HGMP07E putative olfactory receptor maps to the 17p13-->p12 region of the human genome and reveals an MspI restriction fragment length polymorphism. (1993) (14)
Nonfunctional thyroglobulin messenger RNA in goats with hereditary congenital goiter. (1981) (14)
Antibodies in the serum of patients with autoimmune thyroid disorders react with a recombinant 98 amino acid fragment of a full length 64 kDa eye muscle membrane protein which is also expressed in the thyroid. (1992) (14)
The phylogeny, ontogeny, anatomy and regulation of the iodine metabolizing thyroid (2005) (14)
The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis. (1997) (13)
Methylation and expression of the human thyroglobulin gene. (1986) (13)
Monoclonal antibodies with thyroid stimulating activity, at last. (2002) (13)
Linkage relationships and allelic associations of the cystic fibrosis locus and four marker loci (1987) (13)
The thyroglobulin gene evolutionary and regulatory issues (1990) (13)
TSH Receptor Mutations and Diseases (2014) (13)
The structure of a naturally occurring 10K polypeptide derived from the amino terminus of bovine thyroglobulin. (1984) (13)
Growth hormone responses to thyroid hormone in the neonatal rat: resistance and anamnestic response. (1981) (13)
Molecular cloning of bovine thyroglobulin complementary DNA. Characterization of 2500-base-pair and 1900-base-pair fragments. (1980) (12)
Translation in Xenopus oocyte of messenger RNA coding for a beef heavy-chain thyroglobulin. (1974) (12)
Normal level of thyroglobulin messenger ribonucleic acid in a human congenital goiter with thyroglobulin deficiency. (1986) (12)
Unmethylated thyroglobulin promoter may be repressed by methylation of flanking DNA sequences. (1994) (11)
Early in vitro induction of rat pituitary GH mRNA by T31. (1978) (11)
A rare variant, I852M, of the RET proto‐oncogene in a patient with medullary thyroid carcinoma at age 20 years (2001) (11)
Nucleotide sequence of the dog thyrotropin receptor cDNA. (1989) (11)
Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell lines (2002) (11)
Activating mutations of the TSH receptor gene cause thyroid diseases. (1996) (11)
The human genes for calbindin 27 and 29 kDa proteins are located on chromosomes 8 and 16, respectively. (1989) (11)
Recombinant TSH-receptor for determination of TSH-receptor-antibodies. (2009) (11)
Small amplified RNA-SAGE. (2004) (10)
Isolation of rat prolactin messenger ribonucleic acid and synthesis of the complementary deoxyribonucleic acid. (1979) (10)
Importance of the extracellular domain of the human thyrotrophin receptor for activation of cyclic AMP production. (1994) (10)
An in vivo demonstration of functional G protein–coupled receptor dimers (2010) (10)
International System for Cytogenetic Nomenclature (ISCN) — guidelines on cancer cytogenetics (1990) (9)
Improved techniques for the isolation of intact thyroglobulin-synthesizing polysomes. (1977) (9)
Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization (2006) (9)
Chap 75. Thyroid regulatory factors (2015) (9)
Complete nucleotide sequence of a putative G protein coupled receptor: RDC4. (1990) (9)
Prevalence of germline mutations in the TSH receptor gene as a cause of juvenile thyrotoxicosis (2004) (9)
Modulation of thyroglobulin messenger RNA accumulation in the rat thyroid. (1981) (8)
A canonical nerve growth factor-induced gene-B response element appears not to be involved in the cyclic adenosine monophosphate-dependent expression of differentiation in thyrocytes (1999) (8)
Models of thyroid goiter and tumors in transgenic mice (1994) (8)
Differential regulation of thyrotropin receptor and thyroglobulin mRNA accumulation at the cellular level: an in situ hybridization study. (1992) (8)
11 The cAMP in thyroid (1997) (8)
RFLP detected at the 8924 locus by a thyroglobulin cDNA probe (1987) (8)
Monozygotic Twins Are Generally Discordant for Congenital Hypothyroidism from Thyroid Dysgenesis (2009) (8)
The pathophysiological significance of a thyroglobulin-acetylcholinesterase shared epitope in patients with Graves' ophthalmopathy (1989) (7)
Hypo- and Hyperthyroidism Caused by Mutations of the TSH Receptor (1998) (7)
Control by TSH of protein turnover in thyroid subcellular fractions. (1976) (7)
Distinct transcriptional effects of cAMP on 2 thyroid specific genes: thyroperoxidase and thyroglobulin. (1990) (7)
Commentary: Thyrotropin Stimulates Differentiation Not Proliferation of Normal Human Thyrocytes in Culture (2017) (6)
Localization of the genes for human inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) and B (ITPKB) to chromosome regions 15q14-q21 and 1q41-q43, respectively, by in situ hybridization. (1992) (6)
Isolation and characterization of a fragment of rat thyroglobulin gene. (1982) (6)
Complete nucleotide sequence of a putative G protein coupled receptor: RDC7. (1990) (6)
Mutations of calcium-sensing receptor gene: two novel mutations and overview of impact on calcium homeostasis. (2011) (5)
Integrity of the thyroglobulin locus in tricho-rhino-phalangeal syndrome II (1986) (5)
Identification of hormonogenic domains in the carboxyl terminal region of bovine thyroglobulin. (1984) (5)
Demonstration of spontaneous XX/XY chimerism by DNA fingerprinting (1989) (5)
Cloning and characterization of G protein-coupled receptors. (1993) (5)
Citicoline is not protective in experimental models of Huntington's disease (2007) (4)
Comparison of human and porcine TSH receptors. (2000) (4)
Use of DNA bar codes to resolve a canine paternity dispute. (1988) (4)
Simultaneous translation of growth hormone and prolactin messenger RNA from rat pituitary tumor cells (1976) (4)
Normal and defective expression of the thyroglobulin gene. (1980) (4)
Complete nucleotide sequence of a putative G protein coupled receptor: RDC8. (1990) (4)
Lack of responsiveness to 1‐desamino‐d arginin vasopressin (desmopressin) in male patients with nephrogenic syndrome of inappropriate antidiuresis: from bench to bedside (2012) (4)
The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family. (1988) (4)
RFLPs detected at 2 pter-p12 with a thyroid peroxidase cDNA probe, TPO3 (McKusick no. 27450). (1989) (4)
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1-glycoprotein gene family. (1990) (4)
[Structure and expression of thyroglobulin gene]. (1984) (3)
The thyrotropin receptor, a GPCR with a built-in inverse agonist (2003) (3)
Ex vivo Culture of Fetal Mouse Gastric Epithelial Progenitors (2017) (3)
Positive control of proliferation by the cyclic AMP cascade: An oncogenic mechnism of hyper-functional adenoma (1995) (3)
CF screening (1990) (3)
Cross-Reactivity Between Antibodies to Human Thyroglobulin and Torpedo Acetylcholinesterase in Patients With Graves’ Ophthalmopathy (1987) (3)
Human thyroid tissue do not express thyroalbumin (1993) (3)
Studies with Recombinant Autoepitopes of Thyroid Peroxidase (1991) (3)
Localization of human calcyphosine gene (CAPS) to the p13.3 region of chromosome 19 by in situ hybridization. (1990) (3)
A Germline Mutation of the TSH Receptor (TSH-R) Gene Associated with Thyrotoxicosis and Mitral Valve Prolapse (MVP) in a Chinese Family (1999) (3)
Activating mutations of the TSH receptor. (2004) (3)
DNA fingerprinting with wild-type M13 bacteriophage as a probe (1987) (3)
Thyroglobulin complementary DNA as a means to investigate congenital goiters with impaired thyroglobulin synthesis. (1978) (2)
The parable of the mandarin (2005) (2)
Two Novel Mutations of the Calcium Sensing Receptor gene (2008) (2)
The genetics of HIV coreceptors and coreceptor ligands (1999) (2)
[Medical genetics service]. (2002) (2)
The poly (purine) poly (pyrimidine) sequence in the 5' end of the thyroglobulin gene used as a probe, identifies a DNA fingerprint in man. (1990) (2)
INTERPRETATION OF SURFACE ASPECTS OF CELL SECTIONS (1971) (2)
HindIII RFLP on chromosome 8 detected with a calbindin 27 kDa cDNA probe, HBSC21. (1988) (2)
Hereditary angioneurotic oedema successful treatment of one case with metandienone. (1976) (2)
Characterization of the discontinuous epitope of a murine monoclonal antibody with TSAB activity (2003) (2)
Molecular cloning of complementary DNA: preparation of a plasmid vector with low transformation background. (1983) (2)
Control of thyroglobulin gene expression (1987) (1)
Leber's hereditary optic neuropathy: clinical and molecular genetic aspects. Preliminary results in our families. (1992) (1)
Molecular genetics of the thyrotropin receptor. (2009) (1)
Early in vitro induction of rat pituitary GH mRNA by triiodothyronine (1978) (1)
Focus on Gonadotrophin Signalling Speciﬁcity and promiscuity of gonadotropin receptors (2005) (1)
Thyrotropin controls transcription of the thyroglobulin gene ( in vitro transcription / cDNA clones / propylthiouracil / triiodothyronine / hypophysectomy ) (1)
Congenitally hypothyroid mice with (Pax8 −/− ) or without (hyt/hyt) functional TSH receptors (TSHR) display equivalent skeletal phenotypes (2006) (1)
Cloning of the TSH receptor: the story from a Brussels perspective. (2011) (1)
Follicle-stimulating hormone receptor DNA sequencing: investigation into possible glycoprotein receptor mutation in Van Wyk-Grumbach syndrome. (2008) (1)
Crohn disease is associated with the Toll-like receptor (TLR)-4 polymorphism Asp299Gly: further evidence for a deficient bacterial recognition in the triggering of the disease (2003) (1)
[Molecular and diagnostic genetics]. (1990) (1)
Preparation of low-background plasmid vectors for molecular cloning of complementary DNA (1982) (1)
Ovarian hyperstimulation syndrome resulting from a mutation in the follicle-stimulating hormone receptor (2004) (1)
Molecular Cloning of a Thyroid Peroxidase cDNA Fragment Encoding Epitopes Involved in Hashimoto’s Thyroiditis [HT] (1987) (1)
[Preimplantation genetic diagnosis (PGD): the Erasme Hospital experience]. (2008) (1)
Authors’ Response: FSH Receptor Polymorphism and Iatrogenic Ovarian Hyperstimulation (2005) (1)
Molecular Characterization of Thyroid Peroxidase Epitopes (1990) (1)
[Cordocentesis: experience in 391 initial samples]. (1990) (1)
Molecular Genetics of Olfactory receptors (1994) (1)
Regulation of the TPO gene transcription (1990) (1)
IDENTIFICATION OF ORPHAN G PROTEIN‐COUPLED RECEPTORS. (1992) (1)
Manic-depression locus on X chromosome (1991) (1)
A new human hypervariable locus (K29) maps to the q37.3 region of chromosome 2 and reveals a fingerprint. (1991) (1)
TSH receptor action in osteoblasts and osteoclasts in vitro (2006) (1)
Monoclonal antibodies against human TSHR with strong TBII and TBAb activities, recognize a linear epitope modified by a postranslational modification, on the C terminal half of the extracellular domain (2000) (1)
Discordance of Monozygotic twins for Congenital Hypothyroidism: Implications for Screening and for Molecular Pathophysiology (2001) (1)
Preparation of single-stranded deoxyribonucleic acid probes using an immobilized template. (1987) (1)
Control of thyroglobulin gene transcription by TSH and cAMP. (1987) (1)
[Prevention of hemoglobinopathies in Brussels: a necessity?]. (2001) (1)
Analysis of the 5' region of the human thyroglobulin gene (1983) (1)
Pitfall in the use of commercial kits for evaluating pregnancy-specific beta 1-glycoprotein (SP1) (1984) (1)
Discovery and Characterization of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (2014) (1)
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome. (2004) (1)
Nucleotide sequence of a putative transcription factor recognizing the thyroglobulin promoter. (1990) (1)
The Control of Human Thyroid Cell Function, Proliferation and Differentiation (1990) (1)
Control of thyroglobulin gene expression: the role of promoter sequences and their interaction with nuclear proteins (1987) (1)
Diabetes-induced alteration in subcellular distribution of poly(A)-rich RNA from skeletal muscle (2005) (0)
PL-1: MOLECULAR GENETICS AND PATHOLOGY OF THE TSH RECEPTOR (1994) (0)
Stimulating and blocking antibodies to the TSH-receptor have similar affinities and only subtle differences in their epitope recognition (2005) (0)
Models for polyribosomes degradation study. (1970) (0)
Ex vivo culture of adult antral glands. (2017) (0)
Polypeptides having thyrotropin receptor activity encoding nucleic acid sequences for such receptors, and using these polypeptides (1989) (0)
[New genetics and medicine]. (1999) (0)
populations Multiple nonfunctional alleles of CCR5 are frequent in various human (2013) (0)
Study of the activation mechanisms of G protein-coupled receptors using molecular modeling (2001) (0)
Author’s response: Severity of iatrogenic ovarian hyperstimulation syndrome (OHSS) can be predicted by N680allele of FSH receptor (2005) (0)
Cloning of a putative transcription factor recognizing the thyroglobulin gene promoter (1990) (0)
Figure 1, Phylogeny of the development of the thyroid gland. (2015) (0)
[A family of hypervariable minisatellites detected by means of a sequence derived from phage M 13]. (1987) (0)
TSH Receptor Mutations and Thyroid (1998) (0)
bovine chromosome specific minisatellite bovine y (1989) (0)
CLINICAL REVIEW Thyroid Autonomy: Mechanism and Clinical Effects (2001) (0)
[Molecular biology of a genetic malady: thalassemia]. (1976) (0)
Molecular Genetics of Two Major Thyroid Auto-Antigens: Thyroglobulin and Thyroperoxidase (1990) (0)
Activities of C-terminally substituted tachykinin-like peptides in aequorin-based luminescent assays for human and insect neurokinin receptors (2002) (0)
Cyclic nucleotides in thyroid regulation: control of thyroglobulin gene expression by cyclic AMP (1986) (0)
Omissions and misquotations: rewriting history. (2009) (0)
Production of antibodies against the human thyrotropin receptor by genetic immunization (1996) (0)
[Molecular genetics of thyroid diseases]. (1993) (0)
Partial sequencing of bovine thyroglobulin structural gene (1982) (0)
Method for quantitative determination of thyrotropin (TSH) or anti-thryrotropin receptor autoantibodies (anti-TSHR) using a recombinant thyrotropin receptor polypeptide and kit for carrying out this method (1990) (0)
A cAMP-inducible enhancer is located upstream from the thyroglobulin gene in man (1994) (0)
Translation of prolactin and growth hormone messenger RNA from rat pituitary tumour cells. Stimulation of GH mRNA activity by triiodothyronine [proceedings]. (1977) (0)
Ex vivo Culture of Adult Mouse Antral Glands. (2017) (0)
Mutations affecting the serpentine domain of the TSHr can active the receptor by two independent mechanisms (2001) (0)
Strategies to analyse G protein coupled receptors of insects (2001) (0)
[Stimulation of the control of protein synthesis at the level of transduction]. (1971) (0)
Structure-function relationships of CCR5 as a chemokine receptor and HIV co-receptor (1998) (0)
CC CKR-5, CC-chemokine receptor, its derivatives and use thereof (1997) (0)
LGR4-Wnt β-Catenin Signalling Directs GnRH Network Development, with Defects Leading to Self-Limited Delayed Puberty (2019) (0)
Sidney Ingbar Award to Samuel Refetoff. (1997) (0)
Glycoprotein hormone receptors: from disease to structure and function (2004) (0)
Cc-cc chemokinzeptor ckr 5 whose derivatives and uses (1997) (0)
patient-derived and prototype isolates resulting immunodeficiency virus : resistance to macrophage-tropic strains of human macrophages and lymphocytes by Role of CCR 5 in infection of primary (1997) (0)
Study of the promoter region of the human thyroglobulin gene (1983) (0)
[A cloned protein belonging to the G protein-coupled receptor family has an essentially striatal distribution copying that of the major component of the D1 receptor]. (1990) (0)
Molecular cloning of the 8,000 base sequence of bovine thyroglobulin (Tg) structural gene (1981) (0)
Translational control of thyroglobulin synthesis by TSH: Evidence from polyribosome analyses (1977) (0)
A method for the selective determination of blocking autoantibodies against the TSH receptor (2000) (0)
Molecular genetics of Tg and the TSH receptor (1991) (0)
The TSH receptor: from natural variants to structure and function (2007) (0)
Functional expression of a tachykinin-like receptor from stable fly and immunolocalization of orphan receptors in insect tissues (1998) (0)
Thyroid Transcription Factor-1 and thyroglobulin gene expression in primary cultured thyrocytes (1994) (0)
Search for trans-activating factors involved in the control of thyroglobulin gene expression (1990) (0)
Analysis of a locust tyramine receptor expressed in MEL-cells (1998) (0)
Genetic aspects of OHSS (2006) (0)
Mini-satellite bovin sonde specifique au chromosome y des bovines (1990) (0)
Strategies to analyse insect G protein-coupled receptors (GPCRs) (2001) (0)
[G-protein-binding receptors]. (1992) (0)
Subject Index, Vol. 26, 1987 (1987) (0)
active and inactive chemokine cc and nucleic acid molecules encoding such receptors. (1997) (0)
Development of Preimplantation Genetic Diagnosis of aneuplodies and first cases of embryo sexing by Fluorescence in Situ Hybridisation (FISH) and blastocyst transfer (2000) (0)
Comment on: FSH receptor polymorphisms and iatrogenic ovarian hyperstimulation. Authors' reply (2005) (0)
Is bone Morphogenetic Protein 15 (BMP15) a predictive factor for iatrogenic ovarian hyperstimulation syndrome (OHSS) (2006) (0)
Prevalence of the major mutation of the CF gene in Belgian patients. (1991) (0)
Demonstration of TSHr dimerization in living cells (2004) (0)
Carrier prediction of cystic fibrosis in 36 families by means of restriction fragment length polymorphism (1988) (0)
Recognizing the Native Receptor Allows Production of Monoclonal Antibodies Thyrotropin Receptor Causes Thyroiditis and Genetic Immunization Against the Human (1998) (0)
Prevalence of the delta F508 deletion of the cystic fibrosis gene in Belgian patients. (1990) (0)
[Applications of molecular genetics in clinical genetics]. (1987) (0)
LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea: Lgr4/5 in the developing cochlea (2016) (0)
Hereditary Goiter with Thyroglobulin Deficiency (1986) (0)
Thyroid-Stimulating Hormone Receptor Mutations∗∗Chapter titles shaded in green indicate chapters dedicated predominantly to pediatric endocrinology content. (2016) (0)
Revised guidelines for authors of gene mapping reports (2000) (0)
Chemerin: A Link between Innate and Neutrophil-Mediated Maturation of (2017) (0)
Identification of novel peptides and receptors from insects. “Invited plenary lecture” (1998) (0)
Homology scanning between glycoprotein hormone receptors identifie key residues responsible for ligand specificity (2002) (0)
A new mutation in the transmembrane helix V of the FSH receptor responsible of spontaneous ovarian hyperstimulation syndrome (2005) (0)
Establishment of DNA fingerprints in man and in animals using wild type M13 bacteriophage as a probe (1987) (0)
[Applications of molecular genetics to clinical genetics]. (1988) (0)
Molecular cloning of bovine thyroglobulin cDNA (1981) (0)
Reverse transcription of thyroglobulin mRNA [proceedings]. (1977) (0)
Proceedings: Isolation and translation of a 33 s mRNA coding for a beef heavy-chain thyroglobulin. (1974) (0)
Molecular cloning ofa humancannabinoid receptor whichisalsoexpressed intestis (1991) (0)
Functional expression of the Stomoxys calcitrans tachykinin-like receptor in stable Drosophila Schneider 2 cells: an activity study (2000) (0)
Differential activation of an insect G protein-coupled peptide receptor by insectatachykinin-like agonists (2000) (0)
Homology cloning of cDNAs amplified by the polymerase chain reaction: Identification of four new members of the G protein-coupled receptor family (1989) (0)
Normal and defective expression of the thyroglobulin gene. (1980) (0)
Glycoprotein hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
[Isolation of messenger RNAs from thyroglobulin and their translation in the oocyte of Xenopus]. (1973) (0)
Prevalence of the ΔF508 deletion of the cystic fibrosis gene in Belgian patients (1990) (0)
Eleventh International Chromosome Conference (2004) (0)
Determination of the Complete Primary Structure of Bovine Thyroglobulin via cDNA Sequencing and Gene Analysis (1986) (0)
Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [ 9 – 74 ] Processed Variant 1 (2001) (0)
Pharmacological characterization of STKR, a G protein-coupled receptor for insectatachykinin peptide agonists from the stable fly, Stomoxys calcitrans (1999) (0)
Sulfation of the TSH receptor: a undescribed post-translational modification affecting a major epitope recognized by auto-antibodies with blocking activity (2001) (0)
Characterization of the thyroid NADPH oxidases THOX/DUOX as components of the thyroid H2O2 generating system (2002) (0)
The thyroglobulin gene: structure and control of expression (1985) (0)
[Dosage of serum thyroglobulin in clinical practice (author's transl)]. (1980) (0)
Thyroid Transcription Factor 1 and Thyroglobulin gene expression (1996) (0)
Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice ( chloramphenicol acetyltransferase assay / DNA methylation / thyroglobufin gene / transcription control cAMP ) (0)
EcoRI RFLP in the human thyroid peroxidase (TPO) gene on chromosome 2 (1989) (0)
Purification of the natural ligands of orphan neuropeptide receptors from brain extracts (1998) (0)
Non-autoimmune hyper- and hypothyroidism due to mutations in the thyrotropin receptor gene. (1999) (0)
25 Recovery from Mitral Insufficiency after Removal of an Autonomous Hyperfunctioning Thyroid Nodule Causing Hyperthyroidism in a 4-Year-Old Girl (2004) (0)
Membranes and Metabolic Reactions in the Thyroid (1973) (0)
RECEPTOR DOMAINS INVOLVED IN THE INTERACTION WITH CHEMOKINES AND HIV (1999) (0)
Study of membrane-related effects of TSH in thyrocytes: TSH receptor localization and action, and Duox-TPO interaction (2009) (0)
Promoter sequences involved in the positive control of the expression of the thyroglobulin gene by TSH (cAMP) (1986) (0)
Functional characterization of novel G protein-coupled receptors involved in nociception and HIV-1 infection (1997) (0)
Generation of functional antibodies against glycoprotein hormone receptors (2002) (0)
Do sperm cells have flair (1994) (0)
Strategies to analyze G protein-coupled receptors in insect cells (2002) (0)
THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON (2023) (0)
[Structure and expression of the thyroglobulin gene]. (1983) (0)
[Chorionic villi sampling: experience of the initial 500 samples]. (1990) (0)
Thyroperoxidase, anauto-antigen withamosaic structure madeof nuclear andmitochondrial genemodules (1987) (0)
Nucleotide sequenceofa humancannabinoid receptor cDNA (1990) (0)
Glycoprotein hormone receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (0)
Methylation of flanking DNA sequences may repress the activity of the CG-deficient thyroglobulin promoter (1993) (0)
Characterization of an insect tachykinin-like peptide receptor (1999) (0)
Pregnancies after preimplantation genetic diagnosis of Robertsonian translocation t(13 ;14) and blastocyst transfer (2001) (0)
Characterization of two human thyroid proteins from the NADPH Oxidase family: components of the H2O2 generating system (2001) (0)
TSH and TSH receptor relatives in invertebrates (2005) (0)
Functional expression of an insect tachykinin-like receptor in Drosophila S2 cells (1998) (0)
Subject Index Vol. 87, 1999 (2000) (0)
Detection of TSH receptor autoantibodies with affinity-purified antibodies (2003) (0)
Gene therapy, a new arsenal at hand. (1992) (0)
Analysis of insect G protein-coupled receptors (GPCRs) (2001) (0)
Glycoprotein Hormone Receptors: A Unique Paradigm for Ligand Binding and GPCR Activation (2003) (0)
Structure of the 5' region of the human thyroglobulin gene (1983) (0)
In vivo characterization and epitope mapping of monoclonal antibody with full agonistic activity on the TSH receptor (2004) (0)
Identification of Drosophila bursicon as a heterodimeric cystine knot hormone that activates the dLGR2 receptor (2006) (0)
Bis Isolation and partial characterization of a cDNA probe corresponding to the gene for pregnancy-specific Beta1 glycoprotein (1987) (0)
Molecular genetics of hereditary and congenital thyroid diseases (2002) (0)
Ex vivo culture of gastric spheroids (2017) (0)
[Genetic fingerprinting as a tool in identification and in the study of paternity]. (1988) (0)
Comparison of primary and second by estradiol in terms of prolactin s3 accumulation in the pituitary (steroid hormone action/hybridization/cDNA/acellular translati (2016) (0)
Modulation of ligand selectivity by the activation of the transmembrane region of the FSH receptor (2004) (0)
[Thyrotropin receptor. Control of the gene expression and structure function relationships]. (1993) (0)
Regulation of prolactin and growth hormone production (1979) (0)
Evolutive strategy of TSH receptor to avoid promiscuous activation by hCG during pregnancy (2005) (0)
Structure-function relationships of the complement components. (1989) (0)
Spontaneous mutations of the TSH receptor gene increase its constitutive activity and cause thyroid diseases (1996) (0)
Fine structure of the 5' end of the human thyroglobulin gene (1984) (0)
Functional identification of the sequences through which TSH (or cAMP) controls the expression of the thyroglobulin gene (1986) (0)
Study of the control of pro-thyroid hormone (thyroglobulin) gene expression (1986) (0)
Contents Vol. 87, 1999 (2000) (0)
Characterisation of the components of the H2O2 generating system in thyroid (2005) (0)
Nucleic Acids Research (0)
An altered chromatin structure is associated with transcription of the bovine thyroglobulin gene (1986) (0)
[Identification of progenitors of the foetal intestinal epithelium]. (2014) (0)
Functional expression and analysis of the locust tyramine receptor in mel-cells (1998) (0)
Use of gene probe in antenatal diagnosis and carrier detection (1987) (0)
The Genetics of G Protein-Coupled Receptors: Methods for the Post-Genomic Era: Methods in Pharmacology and toxicology (2013) (0)
[Cellular metabolism of thyroid gland and its regulation]. (1973) (0)
COMMENTS ON SMALL-SIZE BUSES (1980) (0)
Reverse transcription of purified prolactin messenger RNA [proceedings]. (1978) (0)

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