Gilbert Vassart
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Philosophy Biology
Gilbert Vassart's Degrees
- PhD Molecular Biology Université libre de Bruxelles
- Doctorate Medicine Université libre de Bruxelles
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(Suggest an Edit or Addition)Gilbert Vassart's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene (1996) (2991)
- Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor (1995) (1817)
- The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54* (2001) (1391)
- Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. (1999) (1323)
- Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation* (2003) (1253)
- Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor (1997) (922)
- ORL1, a novel member of the opioid receptor family (1994) (920)
- Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas (1993) (878)
- Specific Recruitment of Antigen-presenting Cells by Chemerin, a Novel Processed Ligand from Human Inflammatory Fluids (2003) (831)
- Molecular cloning and functional expression of a new human CC-chemokine receptor gene. (1996) (709)
- Molecular cloning of a human cannabinoid receptor which is also expressed in testis. (1991) (684)
- The thyrotropin receptor and the regulation of thyrocyte function and growth. (1992) (634)
- Cloning of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family* (2000) (624)
- Selective amplification and cloning of four new members of the G protein-coupled receptor family. (1989) (621)
- A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA. (1987) (563)
- Molecular cloning of the thyrotropin receptor. (1989) (486)
- Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies. (1989) (399)
- Expression of members of the putative olfactory receptor gene family in mammalian germ cells (1992) (363)
- Germline mutations in the thyrotropin receptor gene cause non–autoimmune autosomal dominant hyperthyroidism (1994) (352)
- Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity (1996) (324)
- A molecular dissection of the glycoprotein hormone receptors. (2004) (324)
- Non-peptide arginine-vasopressin antagonists: the vaptans (2008) (317)
- Control of Thyroglobulin Synthesis and Secretion (1979) (301)
- Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. (1995) (289)
- Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. (1998) (283)
- Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity (2005) (280)
- The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. (1998) (280)
- CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. (1999) (278)
- Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease. (1999) (277)
- DNA fingerprinting in domestic animals using four different minisatellite probes. (1988) (269)
- RDC8 codes for an adenosine A2 receptor with physiological constitutive activity. (1990) (269)
- Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor. (2003) (259)
- ChemR23, a putative chemoattractant receptor, is expressed in monocyte‐derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV‐1 strains (1998) (259)
- Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. (1996) (253)
- Neutrophil-Mediated Maturation of Chemerin: A Link between Innate and Adaptive Immunity1 (2005) (253)
- Somatic and germline mutations of the TSH receptor gene in thyroid diseases. (1995) (252)
- Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland. (1997) (247)
- Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas. (1997) (240)
- Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades. (1995) (238)
- Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA (1985) (230)
- Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. (1995) (222)
- POLYMORPHIC DNA MARKER ON X CHROMOSOME AND MANIC DEPRESSION (1987) (215)
- Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues. (1994) (209)
- Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation (1997) (207)
- Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor. (1998) (206)
- Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors (2002) (200)
- Control of thyroglobulin synthesis and secretion. (First of two parts). (1979) (197)
- Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers (2005) (197)
- Glycoprotein hormone receptors: determinants in leucine‐rich repeats responsible for ligand specificity (2003) (194)
- The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity* (1997) (193)
- The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor. (1991) (190)
- Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter. (1992) (189)
- Distribution of adenosine A2 receptor mRNA in the human brain (1991) (187)
- Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. (2002) (184)
- Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. (2013) (175)
- Thyroperoxidase, an auto‐antigen with a mosaic structure made of nuclear and mitochondrial gene modules. (1987) (170)
- The C-terminal Nonapeptide of Mature Chemerin Activates the Chemerin Receptor with Low Nanomolar Potency* (2004) (170)
- Olfactory receptors are displayed on dog mature sperm cells (1993) (170)
- Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8. (2001) (169)
- Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptor (1990) (168)
- The Core Domain of Chemokines Binds CCR5 Extracellular Domains while Their Amino Terminus Interacts with the Transmembrane Helix Bundle* (2003) (168)
- A 3' splice site mutation in the thyroglobulin gene responsible for congenital goiter with hypothyroidism. (1991) (162)
- Multiple Charged and Aromatic Residues in CCR5 Amino-terminal Domain Are Involved in High Affinity Binding of Both Chemokines and HIV-1 Env Protein* (1999) (160)
- Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones. (1990) (156)
- Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. (2000) (154)
- Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities? (1998) (154)
- Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology. (2002) (153)
- Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. (2002) (151)
- Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism. (1992) (150)
- Human thyrotropin receptor gene: Expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation (1991) (149)
- G protein-coupled receptors: mutations and endocrine diseases (2011) (146)
- Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree. (2007) (146)
- Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2 (2005) (146)
- Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia. (1996) (144)
- Palmitoylation of CCR5 Is Critical for Receptor Trafficking and Efficient Activation of Intracellular Signaling Pathways* (2001) (144)
- Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology. (2006) (144)
- Allosteric Modulation of Binding Properties between Units of Chemokine Receptor Homo- and Hetero-Oligomers (2006) (142)
- A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome. (2004) (140)
- Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid. (1994) (138)
- Constitutive activation of the TSH receptor by spontaneous mutations affecting the N‐terminal extracellular domain (1997) (135)
- Nucleotide sequence of a human cannabinoid receptor cDNA. (1990) (133)
- Premature ovarian aging in mice deficient for Gpr3. (2005) (133)
- LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. (2009) (132)
- Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism. (2004) (130)
- Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (1997) (130)
- The TXP Motif in the Second Transmembrane Helix of CCR5 (2001) (129)
- Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties (2000) (129)
- Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells. (1977) (127)
- An Activation Switch in the Rhodopsin Family of G Protein-coupled Receptors (2005) (126)
- Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity* (1999) (125)
- Identification and characterization of an endogenous chemotactic ligand specific for FPRL2 (2005) (124)
- Defective postnatal development of the male reproductive tract in LGR4 knockout mice. (2006) (123)
- Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene. (1992) (122)
- Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. (2004) (122)
- Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo (2011) (121)
- Development of an animal model of autoimmune thyroid eye disease. (1999) (119)
- The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3. (1996) (117)
- Multiple nonfunctional alleles of CCR5 are frequent in various human populations. (2000) (115)
- Functional characterization of a human receptor for neuropeptide FF and related peptides (2001) (114)
- Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. (1995) (112)
- Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells. (1985) (111)
- A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts. (1987) (110)
- A Conserved Asn in Transmembrane Helix 7 Is an On/Off Switch in the Activation of the Thyrotropin Receptor* (2001) (110)
- Somatic and germline mutations of the TSH receptor and thyroid diseases (2001) (110)
- A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. (2008) (109)
- Cloning and functional characterization of a human A1 adenosine receptor. (1992) (109)
- Molecular cloning, functional expression and pharmacological characterization of a mouse melanocortin receptor gene. (1994) (105)
- Follitropin receptor down-regulation involves a cAMP-dependent post-transcriptional decrease of receptor mRNA expression (1991) (103)
- Mutation of the DRY Motif Reveals Different Structural Requirements for the CC Chemokine Receptor 5-Mediated Signaling and Receptor Endocytosis (2005) (103)
- CCR5 and HIV infection. (2002) (102)
- Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor. (1993) (94)
- Control of thyroperoxidase and thyroglobulin transcription by cAMP: evidence for distinct regulatory mechanisms. (1989) (93)
- Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy (1995) (93)
- Analysis of sequence and structure homologies between thyroglobulin and acetylcholinesterase: possible functional and clinical significance. (1986) (92)
- Thyrotropin controls transcription of the thyroglobulin gene. (1984) (90)
- On the use of DNA fingerprints for linkage studies in cattle. (1990) (87)
- An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene. (1985) (87)
- Allosteric properties of G protein-coupled receptor oligomers. (2007) (87)
- A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger. (1993) (86)
- Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse (2005) (86)
- New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome? (2004) (85)
- Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors (1996) (85)
- Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. (2005) (84)
- The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. (1999) (83)
- Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA. (1987) (82)
- Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor. (2004) (81)
- Defective thyroglobulin synthesis and secretion causing goiter and hypothyroidism. (1993) (81)
- A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons. Possible relationship with D1 dopamine receptor (1990) (81)
- Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector. (1991) (79)
- Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues. (1994) (78)
- Specificity and promiscuity of gonadotropin receptors. (2005) (78)
- TSH receptor and disease (1996) (78)
- Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications. (1987) (77)
- Specific activation of the thyrotropin receptor by trypsin (1996) (77)
- Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene. (2009) (77)
- Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas. (2001) (77)
- Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease. (1991) (76)
- Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH. (1997) (76)
- Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues. (2006) (76)
- Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies (1990) (75)
- Genotypic and gene expression studies in congenital melanocytic nevi: insight into initial steps of melanotumorigenesis. (2009) (74)
- Production of bioactive amino‐terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor (1998) (73)
- Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein. (1992) (73)
- The thyrotropin receptor in thyroid eye disease. (1998) (72)
- Variants of the BMP15 gene in a cohort of patients with premature ovarian failure. (2010) (72)
- Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system (1999) (72)
- Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters. (2000) (71)
- Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi. (2007) (70)
- Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor. (1991) (70)
- TSH Receptor Mutations and Thyroid Disease (1998) (69)
- Generation of a mouse monoclonal TSH receptor antibody with stimulating activity. (2002) (69)
- Differentiation expression during proliferative activity induced through different pathways: in situ hybridization study of thyroglobulin gene expression in thyroid epithelial cells (1990) (68)
- Complete nucleotide sequence of a putative G protein coupled receptor: RDC1. (1990) (67)
- Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution. (1987) (67)
- In vitro and in vivo regulation of thyrotropin receptor mRNA levels in dog and human thyroid cells. (1992) (67)
- Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. (2001) (66)
- A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family. (1999) (66)
- Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors. (2005) (66)
- Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. (2004) (65)
- Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG. (2002) (64)
- Thyroid dysgenesis: multigenic or epigenetic ... or both? (2005) (64)
- GPR3 Receptor, a Novel Actor in the Emotional-Like Responses (2009) (64)
- Possible non-Mendelian mechanisms of thyroid dysgenesis. (2007) (64)
- In Chinese hamster ovary K1 cells dog and human thyrotropin receptors activate both the cyclic AMP and the phosphatidylinositol 4,5-bisphosphate cascades in the presence of thyrotropin and the cyclic AMP cascade in its absence. (1995) (62)
- Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice. (1991) (61)
- The human thyroglobulin gene contains two 15-17 kb introns near its 3'-end. (1983) (61)
- A polymorphic satellite sequence maps to the pericentric region of the bovine Y chromosome. (1989) (61)
- Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene. (1997) (61)
- Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model. (1994) (60)
- Genomic organization of the human thyroglobulin gene: the complete intron-exon structure. (2001) (58)
- Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): measurement of denatured TBG in serum. (1984) (58)
- Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor (1996) (57)
- Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands. (2008) (57)
- Transcriptional regulation of the thyroperoxydase gene by thyrotropin and forskolin (1988) (56)
- Hyperfunctioning malignant thyroid nodule in an 11-year-old girl: pathologic and molecular studies. (2000) (56)
- GRIS: glycoprotein-hormone receptor information system. (2006) (56)
- Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome (2000) (56)
- Transcriptional control of thyroglobulin gene expression by cyclic AMP (1985) (55)
- Localization of human thyrotropin receptor gene to chromosome region 14q3 by in situ hybridization. (1990) (55)
- Translational control of protein synthesis: a simulation study. (1971) (54)
- Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension. (2003) (54)
- Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability. (1992) (54)
- Defective thyroglobulin synthesis and secretion causing goiter and hypothyroidism (1993) (53)
- Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. (1997) (53)
- Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene. (2000) (52)
- Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome (2008) (52)
- Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins. (1994) (52)
- Ontogeny, Anatomy, Metabolism and Physiology of the Thyroid (2015) (52)
- The human pregnancy-specific β1-glycoprotein (PSβG) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family (1988) (51)
- Current developments in G-protein-coupled receptors. (1991) (51)
- Pax 8 expression in primary cultured dog thyrocyte is increased by cyclic AMP. (1996) (50)
- Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant1 (2001) (50)
- The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10 (2005) (50)
- A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis. (1999) (49)
- Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor. (2001) (49)
- A familial case of congenital hypothyroidism caused by a homozygous mutation of the thyrotropin receptor gene. (2001) (49)
- Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope. (1989) (49)
- Clinical review 84: Thyroid autonomy: mechanism and clinical effects. (1996) (49)
- Specific ablation of thyroid follicle cells in adult transgenic mice. (1991) (49)
- The orphan receptor cDNA RDC4 encodes a 5-HT1D serotonin receptor. (1991) (48)
- The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids. (1979) (48)
- Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands (2010) (47)
- The specificity of binding of glycoprotein hormones to their receptors (2008) (46)
- Synthesis of a full length DNA complementary to thyroglobulin 33 S messenger RNA. (1980) (46)
- Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin (1993) (44)
- Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice. (1996) (44)
- Abnormal cellular localization of thyroglobulin mRNA associated with hereditary congenital goiter and thyroglobulin deficiency. (1978) (43)
- Understanding ovarian hyperstimulation syndrome (2005) (43)
- Cloning and sequencing of a calcium‐binding protein regulated by cyclic AMP in the thyroid. (1989) (43)
- Identification of a cAMP-responsive region in thyroglobulin gene promoter (1989) (43)
- Cloning of human thyroglobulin complementary DNA (1982) (42)
- Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA. (2003) (41)
- Thyroid autonomy : Mechanism and clinical effects (1996) (41)
- DNA fingerprinting in man using a mouse probe related to part of the Drosophila 'Per' gene. (1987) (40)
- The TSH receptor and thyroid diseases. (1996) (40)
- Activating mutations of TSH receptor. (2004) (39)
- Studies with recombinant autoepitopes of thyroid peroxidase: evidence suggesting an epitope shared between the thyroid and the gastric parietal cell. (1990) (39)
- Early occurrence of metastatic differentiated thyroid carcinomas in transgenic mice expressing the A2a adenosine receptor gene and the human papillomavirus type 16 E7 oncogene. (1996) (39)
- Translation of thyroglobulin 33S messenger RNA as a means of determining thyroglobulin quaternary structure. (1975) (39)
- Structure-function relationships of two loss-of-function mutations of the thyrotropin receptor gene. (1999) (38)
- Thyroglobulin messenger RNA: translation of a 33-S mRNA into a peptide immunologically related to thyroglobulin. (1975) (38)
- HOMOLOGY BETWEEN THYROGLOBULIN AND ACETYLCHOLINESTERASE: AN EXPLANATION FOR PATHOGENESIS OF GRAVES' OPHTHALMOPATHY? (1986) (38)
- Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage (2016) (38)
- Study of TTF-1 gene expression in dog thyrocytes in primary culture (1995) (37)
- Differentiated carcinomas develop as a consequence of the thyroid specific expression of a thyroglobulin-human papillomavirus type 16 E7 transgene. (1995) (37)
- Functional study of the human thyroid peroxidase gene promoter. (1992) (37)
- Pathology of the TSH receptor. (1999) (37)
- Evolutionary conservation of bursicon in the animal kingdom. (2007) (37)
- Defective splicing of thyroglobulin gene transcripts in the congenital goitre of the Afrikander cattle. (1985) (37)
- Definition, at the molecular level, of a thyroglobulin-acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy. (1989) (36)
- Specific synthesis of thyroglobulin on membrane bound thyroid ribosomes (1972) (36)
- Towards an antigenic map of human thyroglobulin: identification of ten epitope-bearing sequences within the primary structure of thyroglobulin. (1989) (36)
- Thyroid stimulating immunoglobulins, like thyrotropin activate both the cyclic AMP and the PIP2 cascades in CHO cells expressing the TSH receptor (1992) (36)
- Identification of polysomes synthesizing thyroglobulin. (1973) (36)
- Lack of evidence supporting the presence of mRNA for the thyrotropin receptor in extra-ocular muscle (1993) (35)
- Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+-levels in Drosophila S2 cells (2002) (35)
- Molecular weight of thyroglobulin 33 S messenger RNA as determined by polyacrylamide gel electrophoresis in the presence of formamide (1977) (35)
- Control of thyroglobulin synthesis and secretion (second of two parts). (1979) (35)
- Long-Term Follow-Up of an Infant with Thyrotoxicosis due to Germline Mutation of the TSH Receptor Gene (Met453Thr) (1999) (35)
- Thyroid peroxidase gene promoter confers TSH responsiveness to heterologous reporter genes in transfection experiments. (1990) (34)
- Structural organization of the bovine thyroglobulin gene and of its 5'-flanking region. (1987) (34)
- A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist (2002) (34)
- Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers (2012) (34)
- Structure, expression and regulation of the thyroglobulin gene (1985) (33)
- Structural organization of the 5' region of the human thyroglobulin gene. (1984) (33)
- Mapping thyroid peroxidase epitopes using recombinant protein fragments. (1995) (33)
- Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice. (1990) (33)
- The autoimmune response induced by immunising female mice with recombinant human thyrotropin receptor varies with the genetic background (1995) (33)
- The molecular genetics of three thyroid autoantigens: thyroglobulin, thyroid peroxidase and the thyrotropin receptor. (1990) (33)
- Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies. (2008) (32)
- Genomic organization of the 3' region of the human thyroglobulin gene. (2000) (32)
- Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12. (1988) (32)
- Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R. (1994) (32)
- Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor. (1996) (31)
- The human calbindin 27-kDa gene: structural organization of the 5' and 3' regions, chromosomal assignment, and restriction fragment length polymorphism. (1989) (31)
- Ectopic thyroid gland causing dysphonia: imaging and molecular studies. (2010) (31)
- Rarity of anti- Na+/I- symporter (NIS) antibody with iodide uptake inhibiting activity in autoimmune thyroid diseases (AITD). (2000) (31)
- A family with a novel TSH receptor activating germline mutation (p.Ala485Val) (2008) (31)
- Single-nucleotide polymorphism genotyping by melting analysis of dual-labeled probes: examples using factor V Leiden and prothrombin 20210A mutations. (2003) (31)
- Enhancement of cmyc mRNA concentration in dog thyrocytes initiating DNA synthesis in response to thyrotropin, forskolin, epidermal growth factor and phorbol myristate ester. (1986) (31)
- Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population. (2002) (31)
- Constitutively active receptors as a disease-causing mechanism (1994) (30)
- Molecular cloning of a dog thyrotropin (TSH) receptor variant (1990) (30)
- Radioautographic localization of prolactin messenger RNA on histological sections by in situ hybridization (1981) (30)
- The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3----q22.1 and 16q22----q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci. (1991) (30)
- Functional role of TTF‐1 binding sites in bovine thyroglobulin promoter (1992) (30)
- Identification of a thyroid-specific and cAMP-responsive enhancer in the upstream sequences of the human thyroglobulin promoter. (1996) (30)
- Molecular cloning of the 8000-base thyroglobulin structural gene. (2005) (29)
- A physiological role for the posttranslational cleavage of the thyrotropin receptor? (2004) (29)
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- RDC1 may not be VIP receptor. (1992) (29)
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- Alternative splicing may be responsible for heterogeneity of thyroglobulin structure. (1989) (27)
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- The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. (1990) (23)
- Linkage relationships among 20 genetic markers in cattle. Evidence for linkage between two pairs of blood group systems: B-Z and S-F/V respectively. (1990) (23)
- cAMP-dependent binding of a trans-acting factor to the thyroglobulin promoter. (1989) (22)
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- Restriction mapping of synthetic thyroglobulin structural gene as a means of investigating thyroglobulin structure. (1980) (21)
- Human, bovine, canine and rat thyroglobulin promoter sequences display species-specific differences in an in vitro study (1993) (21)
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- The thyroglobulin gene resides on chromosome 8 in man and on chromosome 7 in the rat. (1985) (20)
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- Functional expression of the Stomoxys calcitrans tachykinin-like receptor in stable Drosophila Schneider 2 cells: an activity study (2000) (0)
- Differential activation of an insect G protein-coupled peptide receptor by insectatachykinin-like agonists (2000) (0)
- Homology cloning of cDNAs amplified by the polymerase chain reaction: Identification of four new members of the G protein-coupled receptor family (1989) (0)
- Normal and defective expression of the thyroglobulin gene. (1980) (0)
- Glycoprotein hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- [Isolation of messenger RNAs from thyroglobulin and their translation in the oocyte of Xenopus]. (1973) (0)
- Prevalence of the ΔF508 deletion of the cystic fibrosis gene in Belgian patients (1990) (0)
- Eleventh International Chromosome Conference (2004) (0)
- Determination of the Complete Primary Structure of Bovine Thyroglobulin via cDNA Sequencing and Gene Analysis (1986) (0)
- Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [ 9 – 74 ] Processed Variant 1 (2001) (0)
- Pharmacological characterization of STKR, a G protein-coupled receptor for insectatachykinin peptide agonists from the stable fly, Stomoxys calcitrans (1999) (0)
- Sulfation of the TSH receptor: a undescribed post-translational modification affecting a major epitope recognized by auto-antibodies with blocking activity (2001) (0)
- Characterization of the thyroid NADPH oxidases THOX/DUOX as components of the thyroid H2O2 generating system (2002) (0)
- The thyroglobulin gene: structure and control of expression (1985) (0)
- [Dosage of serum thyroglobulin in clinical practice (author's transl)]. (1980) (0)
- Thyroid Transcription Factor 1 and Thyroglobulin gene expression (1996) (0)
- Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice ( chloramphenicol acetyltransferase assay / DNA methylation / thyroglobufin gene / transcription control cAMP ) (0)
- EcoRI RFLP in the human thyroid peroxidase (TPO) gene on chromosome 2 (1989) (0)
- Purification of the natural ligands of orphan neuropeptide receptors from brain extracts (1998) (0)
- Non-autoimmune hyper- and hypothyroidism due to mutations in the thyrotropin receptor gene. (1999) (0)
- 25 Recovery from Mitral Insufficiency after Removal of an Autonomous Hyperfunctioning Thyroid Nodule Causing Hyperthyroidism in a 4-Year-Old Girl (2004) (0)
- Membranes and Metabolic Reactions in the Thyroid (1973) (0)
- RECEPTOR DOMAINS INVOLVED IN THE INTERACTION WITH CHEMOKINES AND HIV (1999) (0)
- Study of membrane-related effects of TSH in thyrocytes: TSH receptor localization and action, and Duox-TPO interaction (2009) (0)
- Promoter sequences involved in the positive control of the expression of the thyroglobulin gene by TSH (cAMP) (1986) (0)
- Functional characterization of novel G protein-coupled receptors involved in nociception and HIV-1 infection (1997) (0)
- Generation of functional antibodies against glycoprotein hormone receptors (2002) (0)
- Do sperm cells have flair (1994) (0)
- Strategies to analyze G protein-coupled receptors in insect cells (2002) (0)
- THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON (2023) (0)
- [Structure and expression of the thyroglobulin gene]. (1983) (0)
- [Chorionic villi sampling: experience of the initial 500 samples]. (1990) (0)
- Thyroperoxidase, anauto-antigen withamosaic structure madeof nuclear andmitochondrial genemodules (1987) (0)
- Nucleotide sequenceofa humancannabinoid receptor cDNA (1990) (0)
- Glycoprotein hormone receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (0)
- Methylation of flanking DNA sequences may repress the activity of the CG-deficient thyroglobulin promoter (1993) (0)
- Characterization of an insect tachykinin-like peptide receptor (1999) (0)
- Pregnancies after preimplantation genetic diagnosis of Robertsonian translocation t(13 ;14) and blastocyst transfer (2001) (0)
- Characterization of two human thyroid proteins from the NADPH Oxidase family: components of the H2O2 generating system (2001) (0)
- TSH and TSH receptor relatives in invertebrates (2005) (0)
- Functional expression of an insect tachykinin-like receptor in Drosophila S2 cells (1998) (0)
- Subject Index Vol. 87, 1999 (2000) (0)
- Detection of TSH receptor autoantibodies with affinity-purified antibodies (2003) (0)
- Gene therapy, a new arsenal at hand. (1992) (0)
- Analysis of insect G protein-coupled receptors (GPCRs) (2001) (0)
- Glycoprotein Hormone Receptors: A Unique Paradigm for Ligand Binding and GPCR Activation (2003) (0)
- Structure of the 5' region of the human thyroglobulin gene (1983) (0)
- In vivo characterization and epitope mapping of monoclonal antibody with full agonistic activity on the TSH receptor (2004) (0)
- Identification of Drosophila bursicon as a heterodimeric cystine knot hormone that activates the dLGR2 receptor (2006) (0)
- Bis Isolation and partial characterization of a cDNA probe corresponding to the gene for pregnancy-specific Beta1 glycoprotein (1987) (0)
- Molecular genetics of hereditary and congenital thyroid diseases (2002) (0)
- Ex vivo culture of gastric spheroids (2017) (0)
- [Genetic fingerprinting as a tool in identification and in the study of paternity]. (1988) (0)
- Comparison of primary and second by estradiol in terms of prolactin s3 accumulation in the pituitary (steroid hormone action/hybridization/cDNA/acellular translati (2016) (0)
- Modulation of ligand selectivity by the activation of the transmembrane region of the FSH receptor (2004) (0)
- [Thyrotropin receptor. Control of the gene expression and structure function relationships]. (1993) (0)
- Regulation of prolactin and growth hormone production (1979) (0)
- Evolutive strategy of TSH receptor to avoid promiscuous activation by hCG during pregnancy (2005) (0)
- Structure-function relationships of the complement components. (1989) (0)
- Spontaneous mutations of the TSH receptor gene increase its constitutive activity and cause thyroid diseases (1996) (0)
- Fine structure of the 5' end of the human thyroglobulin gene (1984) (0)
- Functional identification of the sequences through which TSH (or cAMP) controls the expression of the thyroglobulin gene (1986) (0)
- Study of the control of pro-thyroid hormone (thyroglobulin) gene expression (1986) (0)
- Contents Vol. 87, 1999 (2000) (0)
- Characterisation of the components of the H2O2 generating system in thyroid (2005) (0)
- Nucleic Acids Research (0)
- An altered chromatin structure is associated with transcription of the bovine thyroglobulin gene (1986) (0)
- [Identification of progenitors of the foetal intestinal epithelium]. (2014) (0)
- Functional expression and analysis of the locust tyramine receptor in mel-cells (1998) (0)
- Use of gene probe in antenatal diagnosis and carrier detection (1987) (0)
- The Genetics of G Protein-Coupled Receptors: Methods for the Post-Genomic Era: Methods in Pharmacology and toxicology (2013) (0)
- [Cellular metabolism of thyroid gland and its regulation]. (1973) (0)
- COMMENTS ON SMALL-SIZE BUSES (1980) (0)
- Reverse transcription of purified prolactin messenger RNA [proceedings]. (1978) (0)
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