Gabriella Gobbi
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Computer Science
Gabriella Gobbi's Degrees
- Masters Computer Science Stanford University
- Bachelors Computer Science University of California, Berkeley
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Why Is Gabriella Gobbi Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gabriella Gobbi is an Italo-Canadian psychiatrist and neuroscientist whose research explores novel treatments for mental health disorders. Gobbi is a professor at McGill University's Department of Psychiatry and a Canada Research Chair in Therapeutics for Mental Health.
Gabriella Gobbi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Correction for Gobbi et al., Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis (2005) (653)
- Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis (2019) (409)
- Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype (2006) (349)
- Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. (2001) (291)
- Cannabinoids Elicit Antidepressant-Like Behavior and Activate Serotonergic Neurons through the Medial Prefrontal Cortex (2007) (284)
- Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain (2018) (179)
- Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery (2018) (173)
- Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review (2016) (170)
- Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. (2001) (169)
- Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design (2010) (159)
- Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission (2010) (149)
- The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. (2009) (144)
- Mirtazapine and paroxetine in major depression: A comparison of monotherapy versus their combination from treatment initiation (2009) (141)
- Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology. (2014) (134)
- Anatomical and cellular localization of melatonin MT1 and MT2 receptors in the adult rat brain (2015) (133)
- Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress (2009) (115)
- The Psychopharmacology of Aggressive Behavior: A Translational Approach Part 1 Neurobiology (2012) (114)
- Genetic Deletion of Fatty Acid Amide Hydrolase Alters Emotional Behavior and Serotonergic Transmission in the Dorsal Raphe, Prefrontal Cortex, and Hippocampus (2010) (110)
- The Psychopharmacology of Aggressive Behavior: A Translational Approach Part 2 Clinical Studies Using Atypical Antipsychotics, Anticonvulsants, and Lithium (2012) (100)
- Promotion of Non-Rapid Eye Movement Sleep and Activation of Reticular Thalamic Neurons by a Novel MT2 Melatonin Receptor Ligand (2011) (99)
- Sleep–wake characterization of double MT1/MT2 receptor knockout mice and comparison with MT1 and MT2 receptor knockout mice (2013) (90)
- Unusually mild tuberous sclerosis phenotype is associated with TSC2 R905Q mutation (2006) (89)
- Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway (2012) (88)
- Monoamine oxidase a gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder (2015) (87)
- Endocannabinoids in the treatment of mood disorders: evidence from animal models. (2009) (85)
- Cannabinoids and emotionality: a neuroanatomical perspective (2012) (79)
- Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex (2006) (78)
- Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: Comparison with antidepressant drugs (2005) (76)
- N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands. (2007) (73)
- Differential Function of Melatonin MT1 and MT2 Receptors in REM and NREM Sleep (2019) (68)
- Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. (2004) (68)
- Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice (2010) (66)
- d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology (2016) (65)
- Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways (2015) (64)
- An index of 5-HT synthesis changes during early antidepressant treatment: α-[11C]methyl-l-tryptophan PET study (2008) (62)
- Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms (2021) (62)
- Efficacy of Topiramate, Valproate, and Their Combination on Aggression/Agitation Behavior in Patients With Psychosis (2006) (62)
- Neurochemical and Psychotropic Effects of Bupropion in Healthy Male Subjects (2003) (61)
- Glut1 deficiency: when to suspect and how to diagnose? (2012) (60)
- Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam (2012) (60)
- Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). (2002) (59)
- d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders. (2018) (56)
- The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors. (2016) (52)
- Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function (2007) (52)
- Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide (2019) (52)
- Melancholic-Like Behaviors and Circadian Neurobiological Abnormalities in Melatonin MT1 Receptor Knockout Mice (2015) (51)
- Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E (2018) (51)
- Effects of fluoxetine at antidepressant doses on short‐term outcome of detoxified alcoholics (1996) (50)
- The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. (2008) (46)
- Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine (2020) (46)
- Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission (2012) (45)
- Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain. (2017) (43)
- Antidepressant actions of ketamine engage cell-specific translation via eIF4E (2020) (43)
- Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression (2016) (42)
- Electrophysiological characterization of dopamine neuronal activity in the ventral tegmental area across the light–dark cycle (2014) (41)
- Monoaminergic Changes in Locus Coeruleus and Dorsal Raphe Nucleus Following Noradrenaline Depletion (2009) (40)
- Characterization of serotonin neurotransmission in knockout mice: implications for major depression (2012) (40)
- Father absence in the monogamous california mouse impairs social behavior and modifies dopamine and glutamate synapses in the medial prefrontal cortex. (2015) (36)
- Brain TRPV1: a depressing TR(i)P down memory lane? (2008) (36)
- Sleep well. Untangling the role of melatonin MT1 and MT2 receptors in sleep (2019) (35)
- The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets (2008) (34)
- Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light–dark cycle (2012) (32)
- Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood. (2012) (31)
- Antinociceptive properties of selective MT(2) melatonin receptor partial agonists. (2015) (30)
- Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission (2021) (30)
- Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood (2014) (29)
- The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus (2016) (28)
- N‐(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands (2009) (28)
- Clozapine blocks dopamine, 5-HT2 and 5-HT3 responses in the medial prefrontal cortex: an in vivo microiontophoretic study (1999) (26)
- Melatonin MT1 receptor as a novel target in neuropsychopharmacology: MT1 ligands, pathophysiological and therapeutic implications, and perspectives. (2019) (25)
- Erratum: Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis (Proceedings of the National Academy of Sciences of the United States of America (December 20, 2005) 102, 51 (18620-18625) DOI: 10.1073/pnas.0509591102) (2006) (25)
- Antidepressant combination versus antidepressants plus second-generation antipsychotic augmentation in treatment-resistant unipolar depression (2018) (22)
- Melatonin, selective and non-selective MT1/MT2 receptors agonists: Differential effects on the 24-h vigilance states (2014) (21)
- Valproate augmentation in a subgroup of patients with treatment-resistant unipolar depression (2016) (20)
- Effects of mirtazapine, paroxetine and their combination: a double-blind study in major depression (2000) (20)
- Male Inmate Profiles and Their Biological Correlates (2014) (19)
- Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle (2019) (18)
- Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex (2009) (18)
- Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity (2017) (17)
- High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: involvement of the prefrontal cortex and dorsal raphe? (2018) (17)
- Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study (2018) (16)
- The selective neuropeptide Y Y5 agonist [cPP1–7,NPY19–23,Ala31,Aib32,Gln34]hPP differently modulates emotional processes and body weight in the rat (2012) (15)
- Alterations of neocortical neuronal responses to acetylcholine and GABA in rats born to alcohol-dependent mothers. (1994) (15)
- Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl- l-carnitine (1995) (15)
- Effects of Chronic Exposure to Low-Dose delta-9-Tetrahydrocannabinol in Adolescence and Adulthood on Serotonin/Norepinephrine Neurotransmission and Emotional Behavior (2020) (14)
- Lysergic acid diethylamide differentially modulates the reticular thalamus, mediodorsal thalamus, and infralimbic prefrontal cortex: An in vivo electrophysiology study in male mice (2021) (14)
- Dysfunction of serotonergic activity and emotional responses across the light‐dark cycle in mice lacking melatonin MT2 receptors (2020) (13)
- Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline (2022) (13)
- Clonidine fails to modify dopaminergic neuronal activity during morphine withdrawal (2001) (12)
- Trace elements among a sample of prisoners with mental and personality disorders and aggression: correlation with impulsivity and ADHD indices. (2019) (10)
- Investigation of the relationship among cortisol, pro-inflammatory cytokines, and the degradation of tryptophan into kynurenine in patients with major depression and suicidal behavior. (2021) (10)
- What is a recommended treatment for aggression in a patient with schizophrenia? (2003) (9)
- Quetiapine in postpartum psychosis. (2014) (8)
- Effects of quetiapine and olanzapine in patients with psychosis and violent behavior: a pilot randomized, open-label, comparative study (2014) (8)
- Practitioner Review: The effects of atypical antipsychotics and mood stabilisers in the treatment of depressive symptoms in paediatric bipolar disorder (2017) (8)
- Hydrocephalus caused by unilateral foramen of Monro obstruction: A review on terminology (2016) (8)
- Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice (2020) (7)
- Growth hormone response to growth hormone-releasing hormone in early abstinent alcoholic patients (1993) (7)
- Short-Term Natural Course of Depressive Symptoms and Family-Related Stress in Adolescents after Separation from Father (2015) (6)
- A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response. (2020) (6)
- MRI Findings in Patients with Clinical Onset Consistent with Infantile Neuroaxonal Dystrophy (INAD), Literature Review, Clinical and MRI Follow-up (2011) (6)
- Melatonin : Therapeutic Value and Neuroprotection (2014) (5)
- Evaluating the Potential Use of Serotonergic Psychedelics in Autism Spectrum Disorder (2022) (5)
- Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signaling (2022) (5)
- Conversion technique from neuroendoscopy to microsurgery in ventricular tumors: Technical note (2016) (5)
- PT628. First in class melatonin MT2 receptors agonists for neuropathic pain (2016) (4)
- N‐(Anilinoethyl)amide Melatonergic Ligands with Improved Water Solubility and Metabolic Stability (2021) (4)
- Translational Research in Suicide: Is It Possible to Study Suicide in Animal Models? (2016) (4)
- Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors (2022) (3)
- S.35.01 Neuropsychopharmacological properties of novel melatonin MT1 receptor ligands (2017) (3)
- P.1.g.109 Distinct role of melatonin MT1 and MT2 receptors in sleep and anxiety: insights from melatonin receptor knockout mice (2014) (2)
- Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome (2022) (2)
- A century of research on psychedelics: A scientometric analysis on trends and knowledge maps of hallucinogens, entactogens, entheogens and dissociative drugs (2022) (2)
- P.0835 Synergistic effects of lysergic acid diethylamide (LSD) and cannabidiol (CBD) (2021) (2)
- Parental Death During Adolescence: A Review of the Literature. (2021) (2)
- Lysergic acid diethylamide (LSD) promotes social behaviour through 5-HT2A and ampa in the medial prefrontal cortex (MPFC) (2021) (2)
- Utility of fine needle aspiration and frozen section in the diagnosis of uncommon thyroid malignancies. (1997) (2)
- Ovarian and cervical thyroid struma. A case report. (1989) (2)
- Melatonin and its Receptors (2017) (1)
- Distinct Effects of Antidepressants in Association With Mood Stabilizers and/or Antipsychotics in Unipolar and Bipolar Depression (2022) (1)
- P.1.046 Effects of fluoxetine on dopaminergic responses at the medial prefrontal cortex (mPFC) (1997) (1)
- Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors. (2022) (1)
- Serotonin firing activity as a marker for mood disorders: lessons from knockout mice. (2005) (1)
- Psychedelic medicine at a crossroads: Advancing an integrative approach to research and practice (2022) (1)
- Sex Differences in Responses to Antidepressant Augmentations in Treatment-Resistant Depression (2022) (1)
- MT2 Melatonin Receptors: Their Role in Sleep and Neuropsychiatric Disorders (2014) (1)
- A role for cannabidiol in psychiatry? Keep calm and follow the drug development rules (2019) (0)
- 24-9 Antidepressant activity of S-adenosyl-L-methionine (SAMe): Effects on neural responses to excitatory amino acids (1997) (0)
- S.27.01 Novel selective melatonin MT2 receptor agonist in the treatment of insomnia (2014) (0)
- Effect of the selective melatonin MT1 receptor partial agonist UCM871 in the activity of noraphineprine neurons of the locus coeruleus during the sleep/wake cycle (2019) (0)
- Laparoscopic cholecystectomy using methyl tert-butyl ether: preliminary results. (1994) (0)
- Examining the association between duration of untreated illness and clinical outcomes in patients with major depressive and bipolar disorders (2022) (0)
- Lurasidone and Mood Stabilizers in Treatment-Resistant Unipolar Depression: A Case Report Study. (2017) (0)
- Franco Fraschini, MD, PhD (1932‐2020) (2020) (0)
- Modulation of Serotonin Firing Activity Through CB1 Agonists and FAAH Inhibitors (2013) (0)
- P.3.046 Effects of clozapine on medial prefrontal cortical cells: A presynaptical hypothesis (1996) (0)
- Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid. (2023) (0)
- P.5.010 Dependence and negative symptoms (1997) (0)
- P.0667 Low-dose desvenlafaxine selectively blocks serotonin reuptake whereas nortriptyline and reboxetine only inhibit norepinephrine reuptake in healthy male volunteers (2021) (0)
- P.3.005 D-lysergic diethylamide modulates dopaminergic neurons of ventral tegmental area via 5-HT1A, D2 and TAAR1 receptors (2017) (0)
- prefrontal cortex: an in vivo microiontophoretic study (1999) (0)
- S.35.02 Anxiolytic, hypnotic and analgesic properties of melatonin MT2 receptor partial agonists (2017) (0)
- Effects of Δ9-Tetrahydrocannabinol, Synthetic Cannabinoids, and Fatty Acid Amide Hydrolase Inhibitors on Mood and Serotonin Neurotransmission (2016) (0)
- A novel intronic variant of SCN1A gene responsible for severe epileptic encephalopathy with refractory status epilepticus (2013) (0)
- [Resection of the sigmoid via laparoscopy: an experimental study of its feasibility]. (1992) (0)
- Bridging the gap in neuropsychiatric translational research. (2022) (0)
- [Acute purulent pancreatitis]. (1977) (0)
- Differential diagnosis of ataxic syndromes in childhood: a five years experience of the Child Neurology and Psychiatry Service in Reggio Emilia (1997) (0)
- [Recurrence after surgical resection of the thyroid for non-toxic goiter: is prevention with suppressive hormonal therapy indicated?]. (1987) (0)
- In-Depth Oral Presentations and Oral Communications (2010) (0)
- Lifetime Cannabis Use Disorder Is Not Associated With Lifetime Impulsive Behavior and Severe Violence in Patients With Schizophrenia Spectrum Disorders From a High-Security Hospital (2021) (0)
- P.2.b.065 Treatment resistant depression (TRD): psychopathological profiles and pharmacological outcomes (2016) (0)
- M-B-035 SLEEP IN MT2 MELATONIN RECEPTOR KNOCKOUT MICE (2011) (0)
- P.668 Lysergic acid diethylamide (LSD) modulates social behavior and neuronal activity of pyramidal neurons in the medial prefrontal cortex (2020) (0)
- PM361. The hallucinogen D-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors (2016) (0)
- Therapeutic Applications of Melatonin in Pediatrics (2014) (0)
- Biomarkers in aggressive behavior (2014) (0)
- S.17.02 Lysergic acid diethylamide reverses anxious-like behaviour and modulates serotonergic neurotransmission in a chronic stress model (2019) (0)
- Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E (2018) (0)
- In-Depth Oral Presentations and Oral Communications IN-DEPTH ORAL PRESENTATIONS HIP ( FIRST HALF ) A new polymer for total hip arthroplasty . First Italian experiences (2010) (0)
- The Y2 receptor antagonist BIIE0246 reverses corticosterone-induced anxiogenic-related behavior and neuronal hypertrophy (2016) (0)
- P.1.115 Changes in regional α-[11C]methyl-L-tryptophan trapping in patients with major depression treated with citalopram augmented with pindolol (2004) (0)
- Disruption of sleep architecture and reticular thalamic (RT) neuronal firing activity in neuropathic pain (2022) (0)
- Melatonin (2021) (0)
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