Gail Petuna Risbridger

Gail Petuna Risbridger's AcademicInfluence.com Rankings

Biology

#12154

World Rank

#15610

Historical Rank

Molecular Biology

#1943

World Rank

#1974

Historical Rank

biology Degrees

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Biology

Gail Petuna Risbridger's Degrees

PhD Molecular Biology University of Melbourne

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Gail Petuna Risbridger's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling (2016) (746)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (509)
Breast and prostate cancer: more similar than different (2010) (225)
Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling (2008) (212)
Activins and inhibins in endocrine and other tumors. (2001) (192)
The Dual, Opposing Roles of Estrogen in the Prostate (2009) (191)
Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium. (2001) (190)
Local aromatase expression in human prostate is altered in malignancy. (2004) (180)
Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland. (2001) (173)
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories (2017) (172)
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer (2019) (168)
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (163)
Estrogen receptor–β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated (2010) (159)
Aromatase and regulating the estrogen:androgen ratio in the prostate gland (2010) (149)
Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development (2010) (145)
Oestrogens and prostate cancer. (2003) (143)
Evaluation of Leydig cell function and gonadotropin binding in unilateral and bilateral cryptorchidism; evidence for local control of Leydig cell function by the seminiferous tubule. (1981) (141)
Immuno- and bioactive inhibin and inhibin α-subunit expression in rat Leydig cell cultures (1989) (132)
Morphometric analysis of the components of the neonatal and the adult rat testis interstitium. (1987) (122)
Induction of apoptosis in low to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones. (2002) (121)
Treating prostate cancer: a rationale for targeting local oestrogens (2007) (119)
The metaplastic effects of estrogen on mouse prostate epithelium: proliferation of cells with basal cell phenotype. (2001) (118)
Inhibin and activin regulate [3H]thymidine uptake by rat thymocytes and 3T3 cells in vitro (1989) (115)
Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia. (2007) (114)
Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors (2012) (108)
Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress. (2020) (107)
Formation of human prostate tissue from embryonic stem cells (2006) (105)
Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis. (2015) (103)
Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in humanprostate and evidence for formation of new activin heterodimers of beta(C)-subunit. (2000) (103)
The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for beta 2-microglobulin in rat brain. (1989) (101)
Activins as regulators of branching morphogenesis. (2001) (100)
Direct response of the murine prostate gland and seminal vesicles to estradiol. (2002) (98)
A preclinical xenograft model of prostate cancer using human tumors (2013) (97)
Evidence that estrogens directly alter androgen-regulated prostate development. (2000) (96)
Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signaling. (2007) (93)
Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status (2012) (91)
Expression and localization of activin subunits and follistatins in tissues from men with high grade prostate cancer. (1997) (88)
Estrogenic effects on prostatic differentiation and carcinogenesis. (2001) (85)
Regulation of prostate branching morphogenesis by activin A and follistatin. (2001) (83)
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (83)
The effect of testicular macrophages and interleukin-1 on testosterone production by purified adult rat Leydig cells cultured under in vitro maintenance conditions. (1993) (81)
Increased endogenous estrogen synthesis leads to the sequential induction of prostatic inflammation (prostatitis) and prostatic pre-malignancy. (2009) (78)
An assessment of Leydig cell function after bilateral or unilateral efferent duct ligation: further evidence for local control of Leydig cell function. (1981) (75)
Prostatic tumor stroma: a key player in cancer progression. (2008) (75)
Current understanding of hypospadias: relevance of animal models (2015) (74)
Growth inhibitory response to activin A and B by human prostate tumour cell lines, LNCaP and DU145. (1997) (72)
Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories. (2017) (71)
Estrogen-regulated development and differentiation of the prostate. (2008) (70)
Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo. (2009) (69)
Stem cells in prostate cancer: treating the root of the problem. (2010) (69)
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy. (2018) (67)
Activin betaC-subunit heterodimers provide a new mechanism of regulating activin levels in the prostate. (2003) (67)
Fibroblast growth factor receptors and their ligands in the adult rat kidney. (2001) (67)
Enduring epigenetic landmarks define the cancer microenvironment (2018) (67)
New Insights on the Morphology of Adult Mouse Penis1 (2011) (66)
Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome (2015) (66)
Effects of experimental cryptorchidism on testicular function in adult rats. (1983) (63)
Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient‐derived xenograft (PDX) models (2018) (62)
An in vivo model of prostate carcinoma growth and invasion in bone (2002) (61)
The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer (2016) (60)
Discrete cell- and stage-specific localisation of fibroblast growth factors and receptor expression during testis development. (2000) (59)
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer. (2013) (58)
Regulation of the transcriptional coactivator FHL2 licenses activation of the androgen receptor in castrate-resistant prostate cancer. (2013) (58)
The involvement of Leydig cells in the regulation of inhibin secretion by the testis. (1989) (58)
Expression of activin A and follistatin core proteins by human prostate tumor cell lines. (1999) (58)
A Preclinical Xenograft Model Identifies Castration-Tolerant Cancer-Repopulating Cells in Localized Prostate Tumors (2013) (58)
Inhibins, activins, and follistatins: Expression of mRNAs and cellular localization in tissues from men with benign prostatic hyperplasia (1998) (57)
Preclinical Models of Prostate Cancer: Patient-Derived Xenografts, Organoids, and Other Explant Models. (2018) (55)
A community-based model of rapid autopsy in end-stage cancer patients (2016) (54)
Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism. (2010) (54)
Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens. (2012) (54)
Prostate phenotypes in estrogen-modulated transgenic mice (2002) (54)
In vitro synthesis and release of inhibin in response to FSH stimulation by isolated segments of seminiferous tubules from normal adult male rats (1988) (53)
Aromatase and prostate cancer. (2006) (53)
Differential localization of fibroblast growth factor receptor-1, -2, -3, and -4 in fetal, immature, and adult rat testes. (1998) (52)
Platelet-derived growth factor ligand and receptor subunit mRNA in the Sertoli and Leydig cells of the rat testis (1995) (50)
βA- and βC-activin, follistatin, activin receptor mRNA and βC-activin peptide expression during rat liver regeneration (2005) (49)
The influence of BRCA2 mutation on localized prostate cancer (2019) (49)
Seasonally and experimentally induced changes in testicular function of the Australian bush rat (Rattus fuscipes). (1984) (48)
Temporal changes in rat Leydig cell function after the induction of bilateral cryptorchidism. (1981) (45)
In vitro modeling of the prostate cancer microenvironment. (2014) (45)
Brief Report: A Bioassay to Identify Primary Human Prostate Cancer Repopulating Cells (2011) (43)
The contribution of inhibins and activins to malignant prostate disease (2001) (42)
Morphology of the external genitalia of the adult male and female mice as an endpoint of sex differentiation (2012) (42)
Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium (2013) (42)
Analysis of the effect of estrogen/androgen perturbation on penile development in transgenic and diethylstilbestrol‐Treated mice (2013) (42)
A pro‐tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment (2014) (41)
Informing Men about Prostate Cancer Screening: A Randomized Controlled Trial of Patient Education Materials (2008) (41)
Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life. (2006) (41)
The role of inhibins and activins in prostate cancer pathogenesis. (2000) (40)
Breaking through a roadblock in prostate cancer research: An update on human model systems (2012) (40)
Differential localization of inhibin subunit proteins in the ovine testis during fetal gonadal development. (1999) (40)
Immuno- and bioactive inhibin and inhibin alpha-subunit expression in rat Leydig cell cultures. (1989) (39)
Estrogen Receptor β Activation Impairs Prostatic Regeneration by Inducing Apoptosis in Murine and Human Stem/Progenitor Enriched Cell Populations (2012) (39)
Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity (2014) (39)
Activins and activin antagonists in the prostate and prostate cancer (2012) (38)
Expression of fibroblast growth factor-8 in adult rat tissues and human prostate carcinoma cells (1996) (38)
Early-Onset Endocrine Disruptor–Induced Prostatitis in the Rat (2008) (37)
Early prostate development and its association with late-life prostate disease (2005) (36)
Identification of receptor tyrosine kinases in the rat testis (1993) (36)
Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate‐tolerant cells (2018) (35)
Physiology of the Male Accessory Sex Structures: The Prostate Gland, Seminal Vesicles, and Bulbourethral Glands (2006) (35)
Molecular profiling of bladder cancer: involvement of the TGF-beta pathway in bladder cancer progression. (2008) (35)
Hypermethylation of the Inhibin α-Subunit Gene in Prostate Carcinoma (2002) (34)
Stage-specific inhibin secretion by rat seminiferous tubules. (1989) (34)
Gestational changes in prostaglandin production by ovine fetal trophoblast cells. (1985) (33)
Role of activins in the male reproductive tract. (2000) (33)
Loss of the Expression and Localization of Inhibinα -Subunit in High Grade Prostate Cancer1 (1998) (33)
Establishment of primary patient‐derived xenografts of palliative TURP specimens to study castrate‐resistant prostate cancer (2015) (33)
Cell-specific expression of βC-activin in the rat reproductive tract, adrenal and liver (2004) (33)
Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment* (2019) (32)
Activin‐βc reduces reproductive tumour progression and abolishes cancer‐associated cachexia in inhibin‐deficient mice (2013) (32)
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation (2013) (32)
Inhibin-related proteins in rat prostate. (1996) (32)
The interaction of hCG, hydroxysteroids and interstitial fluid on rat Leydig cell steroidogenesis in vitro. (1986) (32)
Follitropin (FSH) stimulation of inhibin biological and immunological activities by seminiferous tubules and Sertoli cell cultures from immature rats (1989) (32)
The quantification of steroidogenesis-stimulating activity in testicular interstitial fluid by an in vitro bioassay employing adult rat Leydig cells. (1990) (31)
Development of the external genitalia: perspectives from the spotted hyena (Crocuta crocuta). (2014) (31)
Searching the Internet for information on prostate cancer screening: an assessment of quality. (2004) (30)
Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis (2003) (30)
Adult rat Leydig cell cultures: Minimum requirements for maintenance of luteinizing hormone responsiveness and testosterone production (1992) (30)
17β-Estradiol Induces Apoptosis in the Developing Rodent Prostate Independently of ERα or ERβ (2006) (30)
Convergence of regenerative medicine and synthetic biology to develop standardized and validated models of human diseases with clinical relevance. (2015) (30)
Lineage Enforcement by Inductive Mesenchyme on Adult Epithelial Stem Cells across Developmental Germ Layers (2009) (29)
Localization of immunoreactive beta-endorphin and adrenocorticotropic hormone and pro-opiomelanocortin mRNA to rat testicular interstitial tissue macrophages. (1991) (29)
Re-evaluation of inhibin α subunit as a tumour suppressor in prostate cancer (2004) (28)
Estrogen receptor subtypes dictate the proliferative nature of the mammary gland. (2018) (28)
Elevated level of inhibin-α subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer (2009) (27)
Epigenetic regulation of inhibin alpha-subunit gene in prostate cancer cell lines. (2004) (27)
Should activin βC be more than a fading snapshot in the activin/TGFβ family album? (2005) (27)
betaA- and betaC-activin, follistatin, activin receptor mRNA and betaC-activin peptide expression during rat liver regeneration. (2005) (27)
Effect of cryptorchidism on steroidogenic and mitogenic activities in rat testicular interstitial fluid. (1987) (27)
Minireview: regulation of prostatic stem cells by stromal niche in health and disease. (2008) (26)
Mammary stem cells and parity-induced breast cancer protection- new insights (2017) (26)
Activin-βC modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways (2015) (26)
Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment. (2019) (26)
Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression (2019) (25)
Developmental response by Leydig cells to acidic and basic fibroblast growth factor (1997) (25)
Enhancing active surveillance of prostate cancer: the potential of exercise medicine (2016) (25)
In vivo and in vitro production of inhibin by cryptorchid testes from adult rats. (1989) (25)
Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer. (2021) (24)
A critical role for estrogen signaling in penis development (2019) (24)
SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24+ CD49fhi Mammary Stem Cell-Enriched Compartment (2017) (23)
Localization of Activin b A-, b B-, and b C-Subunits in Human Prostate and Evidence for Formation of New Activin Heterodimers of b C-Subunit * (2000) (23)
The informed man: Attitudes and information needs on prostate cancer screening (2005) (23)
A rare castration‐resistant progenitor cell population is highly enriched in Pten‐null prostate tumours (2017) (23)
Differential effects of the destruction of Leydig cells by administration of ethane dimethane sulphonate to postnatal rats. (1989) (23)
Primary culture and propagation of human prostate epithelial cells. (2013) (23)
Percoll-gradient separation of Leydig cells from postnatal rat testes. (1986) (23)
The therapeutic potential of blocking the activin signalling pathway. (2013) (22)
Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer (2020) (22)
A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts (2016) (22)
The effects of chronic human chorionic gonadotropin treatment on Leydig cell function. (1982) (22)
Influence of the cryptorchid testis on the regeneration of rat Leydig cells after administration of ethane dimethane sulphonate. (1987) (22)
Elevated Expression of Inhibin α in Prostate Cancer (2004) (21)
Anti‐androgenic action by red clover‐derived dietary isoflavones reduces non‐malignant prostate enlargement in aromatase knockout (arko) mice (2003) (21)
Isolation of rat Leydig cells and precursor forms after administration of ethane dimethane sulfonate. (1994) (21)
Expression of estrogen receptor alpha and beta is decreased in hypospadias. (2012) (20)
Mouse hypospadias: A critical examination and definition. (2016) (20)
Aromatase transgenic upregulation modulates basal cardiac performance and the response to ischemic stress in male mice. (2014) (20)
Knowing what’s growing: Why ductal and intraductal prostate cancer matter (2020) (20)
12 – Growth Factors in the Control of Testicular Function (1993) (19)
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology (2021) (19)
Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts (2016) (19)
The inhibin/activin signalling pathway in human gonadal and adrenal cancers. (2014) (19)
Discrete stimulatory effects of platelet-derived growth factor (PDGF-BB) on Leydig cell steroidogenesis (1993) (19)
Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer. (2004) (18)
Hypermethylation of the inhibin alpha-subunit gene in prostate carcinoma. (2002) (18)
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (18)
Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia. (2010) (17)
Effect of unilateral cryptorchidism on the intertubular tissue of the adult rat testis: evidence for intracellular changes within the Leydig cells. (1988) (17)
Should activin betaC be more than a fading snapshot in the activin/TGFbeta family album? (2005) (17)
11 Intragonadal control mechanisms (1987) (17)
Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target12 (2019) (16)
Kallikrein‐related peptidase 4 induces cancer‐associated fibroblast features in prostate‐derived stromal cells (2017) (16)
The power and perils of animal models with urogenital anomalies: handle with care. (2014) (16)
Requirement for heparan sulphate proteoglycans to mediate basic fibroblast growth factor (FGF-2)-induced stimulation of Leydig cell steroidogenesis (1995) (16)
Current perspectives of inhibin biology. (1990) (16)
Effect of serum and serum lipoproteins on testosterone production by adult rat leydig cells in vitro (1992) (16)
Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development (2014) (15)
A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles. (2012) (15)
The path toward identifying prostatic stem cells. (2008) (15)
A loss of estrogen signaling in the aromatase deficient mouse penis results in mild hypospadias. (2019) (15)
Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies (2010) (14)
Alterations in mitogenic and steroidogenic activities in rat testicular interstitial fluid after administration of ethane dimethane sulphonate. (1988) (14)
Elevated expression of inhibin alpha in prostate cancer. (2004) (14)
High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids (2021) (14)
Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer (2020) (14)
Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels (2020) (14)
Epidermal growth factor increases inhibin synthesis by isolated segments of rat seminiferous tubules. (1989) (13)
The role of calcium in luteinizing hormone/human chorionic gonadotrophin stimulation of Leydig cell immunoactive inhibin secretion in vitro (1991) (13)
Inhibin secretion is influenced by Leydig cells: evidence from studies using the cytotoxin ethane dimethane sulphonate (EDS). (1989) (13)
The Role of ERα and ERβ in theProstate: Insights from Genetic Models and Isoform-Selective Ligands (2007) (13)
Establishing a cryopreservation protocol for patient‐derived xenografts of prostate cancer (2019) (13)
Evaluation of the effect of peritubular cell secretions and the testicular paracrine factor P-Mod-S on Leydig cell steroidogenesis and immunoactive inhibin production. (1992) (13)
The role of Eralpha and ERbeta in the prostate: insights from genetic models and isoform-selective ligands. (2006) (13)
Correlations between fibroblast androgen receptor levels and clinical features in abnormal male sexual differentiation and infertility. (1983) (13)
Recent progress in our understanding of inhibin in the prostate gland. (1998) (13)
Loss of the expression and localization of inhibin alpha-subunit in high grade prostate cancer. (1998) (13)
The effect of insulin on inhibin production in isolated seminiferous tubule segments from adult rats cultured in vitro (1989) (13)
Prostate-Regenerating Capacity of Cultured Human Adult Prostate Epithelial Cells (2009) (12)
Site of macrophage inhibition of luteinizing hormone-stimulated testosterone production by purified leydig cells. (1994) (12)
Prostatitis and andrological implications. (2013) (12)
Stimulation of interstitial cell growth after selective destruction of foetal Leydig cells in the testis of postnatal rats (1988) (12)
CRISP3 expression drives prostate cancer invasion and progression. (2020) (12)
The in vivo effect of red clover diet on ventral prostate growth in adult male mice. (2001) (12)
Evidence that heparin binding autocrine factors modulate testosterone production by the adult rat Leydig cell (1996) (12)
Differences in proteins synthesized by fibroblasts from normal individuals and patients with complete testicular feminization. (1982) (12)
Preliminary investigations into triazole derived androgen receptor antagonists. (2014) (12)
Cancer progression: is inhibin α from Venus or Mars? (2004) (11)
PDX: Moving Beyond Drug Screening to Versatile Models for Research Discovery (2020) (11)
New perspectives on growth factor-sex steroid interaction in the prostate. (2003) (11)
Acute effects of ethane dimethane sulfonate (EDS) on the structure of the cauda epididymidis in the rat: selective destruction of clear cells in the proximal cauda region. (1993) (11)
Human cell lines as tools of our trade: "laying it on the (cell) line". (2015) (11)
Computer‐based detection of neonatal changes to branching morphogenesis reveals different mechanisms of and predicts prostate enlargement in mice haplo‐insufficient for bone morphogenetic protein 4 (2005) (11)
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (11)
Effect of ethane dimethane sulphonate on proopiomelanocortin (POMC) mRNA and POMC-derived peptides in the rat testis (1989) (10)
Inhibin and related peptides (1988) (10)
Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone (2018) (10)
High-Aspect-Ratio SU-8-Based Optofluidic Device for Ammonia Detection in Cell Culture Media. (2020) (10)
Synthesis and preliminary investigations into novel 1,2,3-triazole-derived androgen receptor antagonists inspired by bicalutamide. (2014) (9)
Androgen receptor enhancer amplification in matched patient‐derived xenografts of primary and castrate‐resistant prostate cancer (2021) (9)
Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate (2017) (9)
Recent advances in the human physiology of inhibin secretion (1990) (9)
The Evolving Narrative of DNA Repair Gene Defects: Distinguishing Indolent from Lethal Prostate Cancer. (2017) (9)
Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects (2017) (9)
Elevated seminal plasma estradiol and epigenetic inactivation of ESR1 and ESR2 is associated with CP/CPPS (2018) (9)
Inhibition of compensatory renal growth by the N-terminus of a sheep-derived peptide (2009) (9)
Patient-Derived Prostate Cancer: from Basic Science to the Clinic (2016) (9)
Multiple factors with steroidogenesis-regulating activity in testicular interbular fluid from normal and experimentally cryptorchid adult rats (1994) (8)
6 The physiology of testicular inhibin and related proteins (1992) (8)
The prognostic value of stromal FK506‐binding protein 1 and androgen receptor in prostate cancer outcome (2017) (8)
The basic endocrinology of the testis (1995) (8)
Effect of testosterone on serum immunoactive inhibin concentrations in intact and hypophysectomized male rats. (1989) (8)
Activin-βC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice (2015) (8)
Cancer progression: is inhibin alpha from Venus or Mars? (2004) (8)
Variation in the effect of a nongonadotropic Leydig cell stimulating factor in testicular interstitial fluid after exposure of the testis to a single episode of heat treatment. (1987) (8)
Towards best practice in establishing patient-derived xenografts (2017) (8)
Endocrine disruption in the male (2007) (8)
Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells (2020) (7)
Intragonadal control mechanisms. (1987) (7)
Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related (2017) (7)
Chimeric Antigen Receptor T-Cell Therapy in Metastatic Castrate-Resistant Prostate Cancer (2022) (7)
Effects of steroids on fibroblasts: Identification of glucocorticoid-regulated proteins by two-dimensional gel electrophoresis (1983) (6)
17beta-estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta. (2006) (6)
Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer. (2016) (6)
The complexities of identifying a cell of origin for human prostate cancer. (2011) (6)
Autoradiographical localization of luteinizing hormone releasing hormone (LHRH) receptors on rat testicular intertubular cells fractionated on Percoll density gradients. (1985) (6)
Fibroblast studies on clinical androgen insensitivity. (1983) (6)
Regulation of Leydig Cells by Inhibins and Activins (1996) (6)
Stimulatory and inhibitory factors of Leydig cell steroidogenesis are secreted simultaneously by the rat seminiferous tubules and do not affect Leydig cell inhibin production in vitro. (1994) (5)
Epigenetic regulation of inhibin -subunit gene in prostate cancer cell lines (2004) (5)
Changes in Sertoli Cell Structure and Function (1989) (5)
CX-5461 Sensitizes DNA Damage Repair–proficient Castrate-resistant Prostate Cancer to PARP Inhibition (2021) (5)
Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment (2021) (5)
Colorimetric Detection of Extracellular Hydrogen Peroxide Using an Integrated Microfluidic Device. (2022) (5)
Steroidogenesis-stimulating activity in the gonads: comparison of rat testicular fluid with bovine and human ovarian follicular fluids. (1991) (5)
Role of activin C in normal ovaries and granulosa cell tumours of mice and humans. (2018) (4)
Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice (2020) (4)
Local regulation of Leydig cell function by inhibitors of steroidogenic activity. (1992) (4)
Pro‐tumorigenic role of ERα in prostate cancer cells (2015) (4)
Gonadotrophin and steroid binding to adrenal cortex tissue of female brushtail possum, trichosurus vulpecula (1985) (4)
Association of "DNA damage signature" with poor outcome in early prostate cancer. (2015) (4)
Endocrinology of Prostate Cancer (2006) (4)
Reproduction, development, and the early origins of adult disease (2005) (4)
Pro-opiomelanocortin (POMC) gene expression, as identified by in situ hybridization, in purified populations of interstitial macrophages and Leydig cells of the adult rat testis. (1993) (4)
Does bovine follicular fluid stimulate Leydig cell steroidogenesis (1987) (3)
Prostate cancer: Novel xenografts in mice—a new wave of preclinical models (2015) (3)
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (3)
A versatile monoclonal antibody specific to human SERPINB5. (2012) (3)
Interactions between the seminiferous tubules and Leydig cells of the testis. (1990) (3)
Erratum: Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome (2015) (3)
The physiology of testicular inhibin and related proteins. (1992) (3)
Re-evaluating the role of activin-βC in cancer biology. (2015) (3)
Neuroendocrine cells in prostate cancer correlate with poor outcomes: a systematic review and meta‐analysis (2021) (3)
Pituitary peptides in the ovary and testis (1988) (3)
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (3)
[Establishment of a xenograft model of human prostate cancer in mouse]. (2010) (3)
New approaches to targeting epigenetic regulation in prostate cancer (2022) (3)
Three-dimensional bioengineered cancer models (2017) (3)
Association of androgen receptor (AR) copy number gain with ARV7 expression and response to chemotherapy. (2018) (2)
Regulation of Leydig cell function by inhibins and activins (1996) (2)
Prostate cancer cell growth in bone: an in vivo model (2000) (2)
Paracrine mechanisms in the regulation of testicular function. (1991) (2)
New observations on the development of Leydig cell and the paracrine regulation of Leydig cells by the seminiferous tubule (1987) (2)
Cross-species stromal signaling programs human embryonic stem cell differentiation. (2014) (2)
OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer (2022) (2)
Regional localization of activin-βA, activin-βC, follistatin, proliferation, and apoptosis in adult and developing mouse prostate ducts. (2017) (2)
PARP inhibitor and CX-5461 combination therapy as a novel treatment strategy for castrate-resistant prostate cancer (2019) (2)
Role of estrogens in the male reproductive tract. (2004) (2)
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (2)
International Congress on Hormonal Steroids and Hormones and Cancer Oestrogens and prostate cancer (2003) (2)
Hidden clues in prostate cancer - Lessons learned from clinical and pre-clinical approaches on diagnosis and risk stratification. (2021) (2)
To target or not to target the enemy within localized prostate cancer (2013) (2)
Castrate-tolerant cells: what are the implications for the treatment of localized prostate cancer? (2013) (2)
Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer (2020) (1)
946 Identification of castrate-resistant cancer repopulating cells in localised prostate tumours (2013) (1)
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (1)
Editorial: The Future of Our Basic Science and Scientists. (2015) (1)
A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells (2021) (1)
Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels (2020) (1)
Oxytocin receptor antagonists as a novel pharmacological agent for reducing smooth muscle tone in the human prostate (2021) (1)
Inhibin-alpha in prostate cancer: tumour suppressor and pro-metastatic factor (2005) (1)
Stem Cells in Prostate (2005) (1)
Over-Expression of Activin-βC Is Associated with Murine and Human Prostate Disease. (2017) (1)
Androgens vs estrogens in prostate cancer (2003) (1)
Aromatase Overexpression Elicits a Paradoxical Cardiac Response to Ischaemia and Reperfusion Challenge (2013) (1)
A critical look at the inhibin hypothesis in the male (1990) (1)
179. CHARACTERISATION OF THE IN VITRO FUNCTION OF ACTIVIN AC (2009) (1)
Are we disrupted? (2014) (1)
Activins and Inhibins in Cancer Progression (2008) (1)
Patient-Derived Xenograft Models of Prostate Tumors (2017) (1)
Preclinical Evidence of the Efficacy of Lewis Y Car T Cells in Patient-Derived Models of Prostate Cancer (2021) (1)
Chapter 143 – Endocrinology of Benign Prostatic Hyperplasia and Prostate Cancer (2016) (1)
Mast cell interactions at tumour interface drive progression in human prostate cancer (2014) (1)
MicroRNA-194 promotes lineage plasticity in advanced prostate cancer (2019) (1)
Variability in the spontaneous contractility profile of the human prostate gland: implications for a personalized treatment approach to better manage BPH (2016) (1)
Abstract P5-14-03: Withdrawn (2018) (0)
Abstract 155: Cysteine-rich secretory protein 3 expression leads to invasive prostate cancer by modulating cell motility (2019) (0)
Edinburgh Research Explorer SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24(+) CD49f(hi) Mammary Stem Cell-Enriched Compartment (2018) (0)
Targeting oxytocin for the treatment of bladder outlet obstruction due to benign prostatic hyperplasia (2018) (0)
SAT-330 Preclinical Screen of Patient CRPC Tumors Shows Sensitivity to Bromodomain Inhibitors Includes AR-null and Neuroendocrine Disease (2019) (0)
235. Activin C antagonises activin A in vitro and over-expression leads to prostate pathologies in vivo (2008) (0)
Cell-specific expression of POMC in the adult rat testicular interstitium (1992) (0)
PDXs and causing tumour regression in one research-ready PDX as well as the control PDX. An expansion (2021) (0)
MP31-07 ESTROGEN RECEPTOR α REGULATES PROLIFERATION IN PTEN NULL PROSTATE CANCER (2014) (0)
Carboplatin in metastatic castrate resistant prostate cancer: A retrospective study of heavily pretreated patients (COMPACT). (2023) (0)
Advances in preclinical models of prostate cancer for research discovery. (2023) (0)
Using Human Stem Cells to Study the Role of the Stroma in the Initiation of Prostate Cancer (2011) (0)
Abstract B23: Inhibition of ribosomal RNA synthesis as a new therapeutic approach to treat advanced prostate cancer (2017) (0)
Faculty Opinions recommendation of Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. (2006) (0)
Cancer-associated ﬁ broblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells Materials Today Bio (2020) (0)
Abstract 5234: Transcriptome profiling of single prostate cancer cells following androgen deprivation (2018) (0)
Abstract 2106: Estrogen receptor alpha drives proliferation of prostate cancer through PI3K and MAPK signaling (2014) (0)
Clonal Selection of Castrate-Tolerant Stem Cells Leads to Regeneration of Phenotypically Similar Prostate Cancer Tumours (2014) (0)
bal Levels of Specific Histone Modifications and an enetic Gene Signature Predict Prostate Cancer B & P gression and Development (2010) (0)
263: Mimicking the tumour microenvironment (TME): Angiogenesis in tumour progression (2014) (0)
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (0)
Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer (2022) (0)
Myogenic tone is significantly increased in benign prostatic hyperplasia and can be attenuated by sildenafil and tamsulosin, with outcome associated to patient age and prostate volume (2017) (0)
695 Mechanisms of ER beta action in prostate cancer (2010) (0)
Mutation of the DNA damage gene signature to predict for better outcome in malignant melanoma. (2017) (0)
Endocrinology: Its all about good communication (2006) (0)
Mechanistic evidence to support the use of combination therapy to better manage the treatment of LUTS associated with BPH (2017) (0)
Castration induced changes in the expression and localisation of activin beta a-subunit in rat prostate (1998) (0)
Abstract 4076: Single cell RNA analysis reveals heterogeneous sub populations in aggressive variants of prostate cancer (2022) (0)
Activins and Leydig Cell Development Differentiation, and Disease (2007) (0)
Abstract 4809: Combination therapy targeting ribosome biogenesis and mRNA translation provides a novel and potent therapeutic approach to treat MYC-driven malignancy (2016) (0)
Cabazitaxel activity and related metabolic changes in RB1 mutated prostate cancer models (2021) (0)
119. Over-expression of activin βC in vivo reveals a role in male fertility (2005) (0)
Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2018) (0)
1608 SPONTANEOUS CONTRACTIONS IN THE TRANSITION ZONE OF PROSTATES FROM MEN WITH BENIGN PROSTATIC HYPERPLASIA OR ENLARGEMENT ARE NOT BLOCKED BY TAMSULOSIN (2013) (0)
Inhibin and related peptides: emerging issues. (1990) (0)
Endocrine Disruption and Human Prostate Cancer (2008) (0)
The regulation of activin ligand activity by binding proteins in prostate cancer (1997) (0)
The behaviour of Leydig-cells separated on percoll gradients (1985) (0)
Stem Cells In Kidney Morphogenesis (2004) (0)
Novel imaging techniques reveal disturbed function of prostate ducts by alpha1-adrenergic receptor blockers but not by PDE5-inhibitors in the treatment of BPH (2018) (0)
Studies of Leydig cell function in rats with testicular damage, or after chronic lCG treatment (2021) (0)
Mesenchymal/epithelial interplay in the progression to malignancy (1997) (0)
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (0)
57. Temporo-spatial alterations in prostate branching morphogenesis in estrogen-deficient aromatase knockout (ArKO) mice (2003) (0)
Estrogen receptor alpha controls gene expression via translational offsetting (2018) (0)
Endocrinology of the prostate (2010) (0)
Leydig cells are stimulated by follicular fluid (1987) (0)
The future of patient-derived xenografts in prostate cancer research (2023) (0)
The Australian Prostate Cancer BioResource: An update on its role in translational research into prostate cancer in Australia (2007) (0)
Single cell transcriptome analysis reveals human prostate cancer cells upregulate retinoic acid signalling in response to androgen withdrawal (2019) (0)
2569 Identifying high risk features and genomic instability in men with familial prostate cancer (2015) (0)
Short Communication Induction of Apoptosis in Low to Moderate-Grade Human Prostate Carcinoma by Red Clover-derived Dietary Isoflavones 1 (2002) (0)
(2017). Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate. (1), (2017) (0)
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling (2016) (0)
Preparation of a monoclonal antibody for the detection of the novel activin beta c subunit protein in tissues including the benign and malignant human prostate (1998) (0)
Immunohistochemical, ChIP, and microarray analysis reveals how stromal AR controls prostate cancer outcome through fibroblast specific action of androgen signalling on ECM production and DNA licensing (2012) (0)
Paracrine retulation of the testis (1989) (0)
Inhibin and inhibin related proptides (1993) (0)
771: Targeting MYC-driven growth and proliferation in prostate cancer (2014) (0)
Abstract 5181: Dual inhibition of RNA Pol I transcription and PIM kinase as a new therapy to treat prostate cancer (2016) (0)
MP61-04 GENOMIC PROFILING OF KCONFAB MEN WITH A BRCA MUTATION STATUS AND PROSTATE CANCER (2015) (0)
Zone-specific differences in spontaneous contractility of the human prostate gland (2013) (0)
33 Development and maturation of human prostate from embryonic stem cells in vivo (2006) (0)
Follistatins in human prostate evidence for the regulatory role in carcinoma of the prostate (1997) (0)
Abstract 2155: PMR-116, a novel inhibitor of ribosome biogenesis with antitumor activity in preclinical models of prostate cancer (2022) (0)
3D bioengineered microtissues reveal key role of tumour microenvironment in early prostate carcinogenesis (2018) (0)
Oxytocin as a pharmacological target for benign prostatic hyperplasia (2018) (0)
Spontaneous contractions in the transition zone of prostates from men with benign prostatic hyperplasia or enlargement are significantly reduced by combination therapy (2015) (0)
2. Advancing the utility of models of organ development (2003) (0)
Regulation of the transcriptional coactivator FHL2 during cancer progression, a mechanism for androgen receptor activation in castrate resistant prostate cancer (2017) (0)
Prostate disease overview (2014) (0)
All power to the prostatic stroma (2005) (0)
Tumour Stroma Control of Human Prostate Cancer Stem Cells (2013) (0)
Stem Cell Repor ts SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24 + CD49f hi Mammary Stem Cell-Enriched Compar tment (0)
MP31-09 THE EFFECTS OF CURRENTLY USED ANTI-HYPERTENSIVES ON THE CONTRACTILITY OF THE HUMAN PROSTATE GLAND (2015) (0)
Down regulation of the expression and localisation of inhibin alpha subunit in high grade prostate cancer (1997) (0)
Abstract 1997: Charting the DNA methylation landscape of prostate cancer associated fibroblasts (2017) (0)
Oestrogen receptor α promotes prostate cancer progression through dual actions in both epithelia and stroma (2015) (0)
Differential expression of follistatin protein isoforms may confer selective growth advantages on prostate cells and tissues in the presence of activin a (1998) (0)
New patient-derived models of castrate-sensitive and castrate-resistant prostate cancer. (2020) (0)
Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate (2017) (0)
383 Apoptosis and Regenerative Potential in Castrate-resistant Stem Cells of the Prostate Gland Regulated by Estrogen Receptor Beta (2012) (0)
New combination therapies for castration-resistant prostate cancer (2019) (0)
Foreword to 'Estrogens and Male Health' (2001) (0)
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (0)
Abstract 3575: Integration of estradiol signaling at the translational and transcriptional level in prostate cancer cells. (2013) (0)
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (0)
Immunolocalisation of fibroblast growth factor receptors 1-4 in adult rat testes (1997) (0)
MP44-12 ESTROGEN DIRECTLY MODULATES SPONTANEOUS CONTRACTILITY WITHIN THE HUMAN PROSTATE (2016) (0)
Adult Prostate Stem Cells (2014) (0)
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (0)
Estrogen receptor positive luminal progenitors the cancer cell origin for Estrogen receptor positive breast cancer (2019) (0)
MP44-15 SPONTANEOUS MYOGENIC CONTRACTILITY IN THE HUMAN PROSTATE GLAND: IMPLICATIONS FOR THE TREATMENT OF LUTS ASSOCIATED WITH BPH. (2016) (0)
PD04-02 USING GENOMIC AND TRANSCRIPTOMIC PROPERTIES TO DETERMINE ANDROGEN RESPONSE IN DUCTAL PROSTATE CANCERS AND DETERMINE EFFICACY OF POLY(ADP-RIBOSE) POLYMERASE INHIBITORS WITH ANDROGEN SIGNALLING INHIBITORS THERAPY IN VITRO (2023) (0)
Contemporary approaches to prostate cancer research (2011) (0)
Abstract B100: High-risk pathologic and genomic features of BRCA2-mutant prostate cancer (2018) (0)
Estrogen response by anterior prostate involves stromal estrogen receptor, er alpha (1998) (0)
Expression of fibroblast growth factors and their receptors in fetal immature and adult rat testis (1998) (0)
Pre-clinical model detects castrate-resistant cancer repopulating cells in localised prostate tumours (2013) (0)
Biological and immunological properties of inhibin related proteins (1993) (0)
Interaction of activin and follistatin in prostate cancer : comparison between in vitro and in vivo follistatin expression (1997) (0)
New patient-derived ex vivo models for rapid preclinical testing with prostate cancer (2018) (0)

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What Schools Are Affiliated With Gail Petuna Risbridger?

Gail Petuna Risbridger is affiliated with the following schools: