Gail R. Martin
#16,660
Most Influential Person Now
American biologist
Gail R. Martin's AcademicInfluence.com Rankings
Gail R. Martinbiology Degrees
Biology
#693
World Rank
#1214
Historical Rank
#384
USA Rank
Genetics
#191
World Rank
#235
Historical Rank
#102
USA Rank
Molecular Biology
#242
World Rank
#246
Historical Rank
#102
USA Rank
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Biology
Gail R. Martin's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is Gail R. Martin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gail Roberta Martin is an American biologist. She is professor emerita in the Department of Anatomy, University of California, San Francisco. She is known for her pioneering work on the isolation of pluripotent stem cells from normal embryos, for which she coined the term ‘embryonic stem cells’. She is also widely recognized for her work on the function of Fibroblast Growth Factors and their negative regulators in vertebrate organogenesis. She and her colleagues also made valuable contributions to gene targeting technology.
Gail R. Martin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. (1981) (5764)
- Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. (1988) (4395)
- MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts (2008) (2253)
- The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. (1995) (1261)
- An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination (1998) (1092)
- Midbrain development induced by FGF8 in the chick embryo (1996) (761)
- A positive feedback loop coordinates growth and patterning in the vertebrate limb (1994) (724)
- Teratocarcinomas and mammalian embryogenesis. (1980) (715)
- Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. (1975) (703)
- Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. (1992) (696)
- The branching programme of mouse lung development (2008) (696)
- FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb (1993) (691)
- The roles of FGFs in the early development of vertebrate limbs. (1998) (670)
- Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. (1999) (657)
- Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo (1995) (629)
- Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation (1997) (607)
- Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development (1996) (602)
- Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. (1997) (584)
- FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations (1994) (564)
- Functions of FGF signalling from the apical ectodermal ridge in limb development (2002) (563)
- Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. (1999) (539)
- Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. (1999) (516)
- c-Myc regulates mammalian body size by controlling cell number but not cell size (2001) (460)
- Fgf8 signalling from the AER is essential for normal limb development (2000) (459)
- Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. (1997) (428)
- FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. (1999) (413)
- FGF-4 and BMP-2 have opposite effects on limb growth (1993) (390)
- SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. (2004) (373)
- Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line (1997) (368)
- Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation (1987) (368)
- Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers (2006) (350)
- Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. (2005) (349)
- Teratocarcinomas as a model system for the study of embryogenesis and neoplasia (1975) (342)
- The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum (2003) (340)
- Genetic evidence that FGFs have an instructive role in limb proximal–distal patterning (2008) (340)
- BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. (1999) (330)
- Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. (1999) (322)
- A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula (2006) (317)
- En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis. (1987) (312)
- Analysis of Fgf8 gene function in vertebrate development. (1997) (290)
- Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. (2006) (286)
- Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. (1990) (286)
- Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development (2000) (285)
- Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. (1990) (265)
- Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. (2005) (253)
- Deciphering skeletal patterning: clues from the limb (2003) (240)
- FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons (2005) (231)
- The development of cystic embryoid bodies in vitro from clonal teratocarcinoma stem cells. (1977) (217)
- mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation. (1991) (200)
- Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain (2003) (188)
- Virus infection of murine teratocarcinoma stem cell lines (1977) (187)
- Fibroblast growth factor signalling in the hair growth cycle: Expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle (1996) (182)
- FGF 8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx 2 expression (1999) (181)
- Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development. (1986) (180)
- Cre–mediated chromosome loss in mice (1997) (177)
- Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. (2008) (175)
- Control of Mitotic Spindle Angle by the RAS-Regulated ERK1/2 Pathway Determines Lung Tube Shape (2011) (165)
- Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor (2010) (164)
- Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo. (1989) (164)
- An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors (2007) (162)
- Expression of N-myc in teratocarcinoma stem cells and mouse embryos (1985) (161)
- An FGF response pathway that mediates hepatic gene induction in embryonic endoderm cells. (2006) (161)
- Analysis of mouse Evx genes: Evx-1 displays graded expression in the primitive streak. (1992) (154)
- Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr). (1993) (153)
- Kidney Development in the Absence of Gdnf and Spry1 Requires Fgf10 (2010) (144)
- The morphology and growth of a pluripotent teratocarcinoma cell line and its derivatives in tissue culture. (1974) (142)
- The ECM protein nephronectin promotes kidney development via integrinα 8β1-mediated stimulation of Gdnf expression (2007) (140)
- Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development (2008) (131)
- Mosaic mice with teratocarcinoma-derived mutant cells deficient in hypoxanthine phosphoribosyltransferase. (1977) (130)
- Teratocarcinoma stem cells (1983) (126)
- Teratocarcinoma stem cells have a cell surface carbohydrate-binding component implicated in cell-cell adhesion (1979) (117)
- Multiple differentiation of clonal teratocarcinoma stem cells following embryoid body formation in vitro (1975) (112)
- Cardiac conduction is required to preserve cardiac chamber morphology (2010) (109)
- Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos (1985) (108)
- Muscle-specific cell ablation conditional upon Cre-mediated DNA recombination in transgenic mice leads to massive spinal and cranial motoneuron loss. (1998) (108)
- Cell surface antigens of clonal teratocarcinoma cells at various stages of differentiation (1975) (106)
- The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation. (1996) (104)
- The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression. (2007) (103)
- SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling (2011) (103)
- Molecular probes define different regions of the mouse t complex (1985) (103)
- Methylation of the mouse hprt gene differs on the active and inactive X chromosomes (1986) (101)
- Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal. (2006) (100)
- Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function (2006) (97)
- Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic development. (1987) (92)
- Cut, paste, and save: New approaches to altering specific genes in mice (1989) (89)
- Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples. (2006) (88)
- Expression of a high molecular weight cell surface glycoprotein (LETS protein) by preimplantation mouse embryos and teratocarcinoma stem cells. (1978) (84)
- FGF-4 regulates expression of Evx-1 in the developing mouse limb. (1993) (69)
- Pluripotent embryonic stem cell lines can be derived from tw5/tw5 blastocysts (1982) (66)
- Embryonic expression of Fgf-6 is restricted to the skeletal muscle lineage. (1993) (64)
- Menin determines K-RAS proliferative outputs in endocrine cells. (2014) (63)
- Making a vertebrate limb: new players enter from the wings. (2001) (63)
- Effects of cell adhesion of the substratum on the growth of chick embryo fibroblasts. (1974) (62)
- Fate and function of the ventral ectodermal ridge during mouse tail development. (2000) (57)
- Four classes of mRNA are expressed from the mouse int‐2 gene, a member of the FGF gene family. (1988) (56)
- Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. (2009) (56)
- Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex. (1987) (53)
- Function of FGF‐4 in limb development (1994) (51)
- Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development. (1995) (46)
- Visceral endoderm-1 (VE-1): an antigen marker that distinguishes anterior from posterior embryonic visceral endoderm in the early post-implantation mouse embryo (1995) (45)
- ROLE OF THE HIGH‐MOLECULAR‐WEIGHT GLYCOPROTEIN IN CELLULAR MORPHOLOGY, ADHESION, AND DIFFERENTIATION * (1978) (44)
- Loss of Apoptosis-Inducing Factor Results in Cell-Type-Specific Neurogenesis Defects (2008) (41)
- Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5. (1990) (39)
- Isolation and analysis of embryonic expression of Hox-4.9, a member of the murine labial-like gene family (1992) (39)
- Developmentally regulated use of alternative promoters creates a novel platelet-derived growth factor receptor transcript in mouse teratocarcinoma and embryonic stem cells (1989) (38)
- Protein synthetic patterns in teratocarcinoma stem cells and mouse embryos at early stages of development. (1978) (38)
- A fucan specific lectin on teratocarcinoma stem cells. (1981) (36)
- Why thumbs are up (1995) (36)
- Sprouty genes function in suppression of prostate tumorigenesis (2012) (31)
- Teratocarcinoma stem cell adhesion: the role of divalent cations and a cell surface lectin (1983) (30)
- Establishment of embryonic stem cell lines from preimplantation mouse embryos homozygous for lethal mutations in the t-complex. (1987) (28)
- Studies of the temporal relationship between the cytogenetic and biochemical manifestations of X-chromosome inactivation during the differentiation of LT-1 teratocarcinoma stem cells. (1984) (27)
- Genetic approaches for studying programmed cell death during development of the laboratory mouse. (1995) (27)
- Synteny on mouse chromosome 5 of homologs for human DNA loci linked to the Huntington disease gene. (1989) (27)
- Tunicamycin reversibly inhibits the terminal differentiation of teratocarcinoma stem cells to endoderm. (1983) (23)
- Developmental potential of teratocarcinoma stem cells in utero following aggregation with cleavage-stage mouse embryos. (1983) (21)
- X-chromosome inactivation in mammals (1982) (19)
- A Cre transgene active in developing endodermal organs, heart, limb, and extra‐ocular muscle (2008) (18)
- Incorporation of teratocarcinoma stem cells into blastocysts by aggregation with cleavage-stage embryos. (1980) (17)
- Isolation of embryonic stem cell-like colonies from porcine embryos (1988) (16)
- Isolation of a teratocarcinoma stem cell lectin implicated in intercellular adhesion (1985) (15)
- An alpha globin pseudogene is located within the mouse t complex (2004) (15)
- 28 – DETECTION OF HOMOLOGOUS RECOMBINANTS (1990) (12)
- Mixed signals from the AER: FGF-4 and Bmp-2 have opposite effects on limb growth. (1993) (10)
- Twentieth-century Mexico (1988) (8)
- Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development (2009) (5)
- Use of Teratocarcinoma Cells as a Model System for Studying the Cell Surface During Early Mammalian Development (1980) (4)
- Protein synthesis and differentiation in a clonal line of teratocarcinoma and in preimplantation mouse embryo. (1979) (4)
- The Differentiation of Teratocarcinoma Stem Cells in vitro: Parallels to Normal Embryogenesis (1977) (4)
- Use of teratocarcinoma stem cells as a model system for the study of X-chromosome inactivation in vitro. (1978) (3)
- Mosaic analysis reveals essential function of FGF receptor 2 in mammary gland branching morphogenesis (2006) (2)
- The ECM protein nephronectin promotes kidney development via integrin (cid:3) 8 (cid:2) 1-mediated stimulation of Gdnf expression (2007) (1)
- Sproutyl is a critical regulator of kidney development by antagonizing GDNF/Ret-mediated signals during ureteric bud morphogenesis (2005) (1)
- An alpha globin pseudogene is located within the mouse t complex (2004) (1)
- The Mouse En-1 Gene Encodes a Nuclear Protein Expressed in the Nervous System of the Developing Embryo (1989) (1)
- Control Of Mitotic Spindle Angle By RAS-Regulated ERK1/2 Signaling Determines Lung Tube Shape (2012) (1)
- Author index (1995) (0)
- En-I and En-2 , two mouse genes with sequence homology to the D r o s o p h i l a ng . ral " led gene : expression unng embryogenesls (2007) (0)
- Program/Abstract #24Publishing science (2008) (0)
- Sprouty1 and Sprouty2 gene function in mouse lung development (2009) (0)
- 57 The role of fgf8 and neuroepithelial boundaries in midbrain, isthmus, and cerebellar development (1996) (0)
- Two proto-oncogenes implicated in mammary carcinogenesis , inti and int-2 , are independently regulated during mouse development ( oncogenes / mouse mammary tumor virus / embryos / teratocarcinoma cells / testes ) (0)
- Sprouty function in pancreas morphogenesis (2009) (0)
- Volume contents (1995) (0)
- ARY mouse Fgf 8 gene encodes a family of polypeptid ns that direct outgrowth and patterning in the d (1995) (0)
- Function of Sproutys in salivary gland branching morphogenesis (2009) (0)
- Negative Regulation of Lens Cell Proliferation and Fiber Differentiation by Sprouty (2010) (0)
- Gail Roberta Martin (1944– ) (2019) (0)
- 13-P066 SPROUTY1 and RTK signaling in kidney development (2009) (0)
- What comes after a career in science? Asian Art! (2019) (0)
- Sprouty Prevents TGFβ-Induced Cataractogenesis (2010) (0)
- Genetic analysis of BMP-mediated cell survival in the limb bud mesenchyme (2007) (0)
- The UCSF Mouse Inventory Database Application, an Open Source Web App for Sharing Mutant Mice Within a Research Community (2020) (0)
- WITHDRAWN: Genetic analysis of Fgf gene function in the limb (2007) (0)
- An FGF signaling loop sustains the generation of differentiated progeny from incisor epithelial stem cells in mice (2007) (0)
- Genetic loss of function studies indicate a key role for sprouty proteins in limiting RTK/MAPK function (2006) (0)
- 22 – Identification and Characterization of Two Mouse Genes, En-1 and En-2 with Sequence Homology to the engrailed and invected Genes of Drosophila (1991) (0)
- The role of Sprouty1 in cardiac fibroblasts and epicardium (2009) (0)
- Abstract 2944: Targeting negative feedback signaling in tyrosine kinase-driven malignancies (2012) (0)
- In the twentieth and early twenty-first centuries (2019) (0)
- Nan Tang Pathway Determines Lung Tube Shape Control of Mitotic Spindle Angle by the RAS-Regulated ERK 1 / 2 (2014) (0)
- Differentiation and growth of cells in vertebrate tissues edited by G. Goldspink. Pp. 323. (Halsted Press, John Wiley and Sons: New York). $32.50 (1975) (0)
- Introducing WIREs Developmental Biology (2012) (0)
- Regulation of airway shape by SPROUTY-mediated control of oriented cell division (2010) (0)
- Generation and Analysis of Mice Carrying an Allelic Series of Mutations at the Fgf8 Locus Demonstrate Requirements for FGF8 During Gastrulation, Limb, Craniofacial, Cardiac and CNS Development • 286 (1998) (0)
- Negative Feedback Signaling Enables Leukemic Transformation by Oncogenic Tyrosine Kinases (2012) (0)
- On the threshold of molecular development Development in mammals. volume 5. Edited by M. H. Johnson. Amsterdam: Elsevier. (1983). 381 pp. $93.00 (1984) (0)
- silenced in mouse and human B-cell lymphomas Expression of sprouty2 inhibits B-cell proliferation and is epigenetically (2009) (0)
- Fgf8 Is Required for Specification of the Left-Right Axis and for Normal Cardiac Development in Mice (1999) (0)
- LOSS OF SPROUTY GENE FUNCTION LEADS TO DENTAL ANOMALIES BY RENDERING DENTAL TISSUES HYPERSENSITIVE TO FGF SIGNALING (2007) (0)
- Analysis of a lethal mutation (tw18) in the mouse t-complex. (1988) (0)
- Genetic analysis of Fgf gene function in the limb (2007) (0)
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