Galen B. Toews
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Philosophy Biology
Galen B. Toews's Degrees
- Doctorate Medicine University of Manitoba
- PhD Physiology University of Manitoba
Why Is Galen B. Toews Influential?
(Suggest an Edit or Addition)Galen B. Toews's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. (1980) (960)
- Analysis of the Lung Microbiome in the “Healthy” Smoker and in COPD (2011) (811)
- Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. (1990) (709)
- Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial (1995) (658)
- Mechanisms of pulmonary fibrosis. (2004) (631)
- Histopathologic variability in usual and nonspecific interstitial pneumonias. (2001) (622)
- Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis? (2004) (582)
- Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis. (2001) (550)
- Radiological versus histological diagnosis in UIP and NSIP: survival implications (2003) (513)
- Prognostic implications of physiologic and radiographic changes in idiopathic interstitial pneumonia. (2003) (487)
- Prognostic value of desaturation during a 6-minute walk test in idiopathic interstitial pneumonia. (2003) (481)
- CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury. (2005) (452)
- Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring. (1997) (417)
- Idiopathic pulmonary fibrosis: predicting response to therapy and survival. (1998) (408)
- A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. (2006) (388)
- Idiopathic pulmonary fibrosis: prognostic value of changes in physiology and six-minute-walk test. (2006) (350)
- Protection from Pulmonary Fibrosis in the Absence of CCR2 Signaling1 (2001) (337)
- Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. (2007) (304)
- Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. (2003) (302)
- The role of CCL12 in the recruitment of fibrocytes and lung fibrosis. (2006) (299)
- Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. (2009) (291)
- Role of Antibiotics and Fungal Microbiota in Driving Pulmonary Allergic Responses (2004) (283)
- Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival (1997) (274)
- An essential role for fibronectin extra type III domain A in pulmonary fibrosis. (2008) (263)
- CCR2 Expression Determines T1 Versus T2 Polarization During Pulmonary Cryptococcus neoformans Infection1 (2000) (263)
- A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection (1989) (258)
- Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts (2005) (255)
- Fibroblastic foci in usual interstitial pneumonia: idiopathic versus collagen vascular disease. (2003) (245)
- The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection. (1995) (239)
- Pathogenic Yeasts Cryptococcus neoformans and Candida albicans Produce Immunomodulatory Prostaglandins (2001) (236)
- Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome (2002) (234)
- Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion. (2004) (234)
- Corneal allografts fail to express Ia antigens (1979) (231)
- Afferent phase production of TNF-alpha is required for the development of protective T cell immunity to Cryptococcus neoformans. (1996) (229)
- Idiopathic interstitial pneumonia: do community and academic physicians agree on diagnosis? (2007) (227)
- Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis. (2010) (221)
- CCL18 as an indicator of pulmonary fibrotic activity in idiopathic interstitial pneumonias and systemic sclerosis. (2007) (204)
- Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). (2006) (202)
- Significance of the microbiome in obstructive lung disease (2012) (202)
- Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model. (1996) (202)
- Protection from pulmonary fibrosis in leukotriene-deficient mice. (2002) (198)
- Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. (1999) (193)
- Lung Resident Mesenchymal Stem Cells Isolated from Human Lung Allografts Inhibit T Cell Proliferation via a Soluble Mediator1 (2008) (192)
- Sildenafil preserves exercise capacity in patients with idiopathic pulmonary fibrosis and right-sided ventricular dysfunction. (2013) (185)
- Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts1 (2004) (184)
- Differential Roles of CC Chemokine Ligand 2/Monocyte Chemotactic Protein-1 and CCR2 in the Development of T1 Immunity1 (2002) (176)
- Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival. (2001) (173)
- Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans. (1995) (169)
- The accessory cell function of human alveolar macrophages in specific T cell proliferation. (1984) (161)
- Depletion of CD4+ (L3T4+) lymphocytes in vivo impairs murine host defense to Cryptococcus neoformans. (1990) (161)
- Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent. (2002) (158)
- GM-CSF Regulates Bleomycin-Induced Pulmonary Fibrosis Via a Prostaglandin-Dependent Mechanism (2000) (156)
- Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99. (2009) (150)
- Role of IFN-γ in Regulating T2 Immunity and the Development of Alternatively Activated Macrophages during Allergic Bronchopulmonary Mycosis 1 (2005) (148)
- Induction of Interleukin-12 and Gamma Interferon Requires Tumor Necrosis Factor Alpha for Protective T1-Cell-Mediated Immunity to Pulmonary Cryptococcus neoformans Infection (2002) (148)
- Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitrofluorobenzene sensitization. (1980) (146)
- Production of Prostaglandins and Leukotrienes by Pathogenic Fungi (2002) (144)
- Integrin alpha4beta1 regulates migration across basement membranes by lung fibroblasts: a role for phosphatase and tensin homologue deleted on chromosome 10. (2003) (143)
- Accumulation of CD11b+ Lung Dendritic Cells in Response to Fungal Infection Results from the CCR2-Mediated Recruitment and Differentiation of Ly-6Chigh Monocytes12 (2009) (140)
- The relationship of inoculum size to lung bacterial clearance and phagocytic cell response in mice. (2015) (136)
- Bleomycin-Induced E Prostanoid Receptor Changes Alter Fibroblast Responses to Prostaglandin E21 (2005) (136)
- TLR9 Differentiates Rapidly from Slowly Progressing Forms of Idiopathic Pulmonary Fibrosis (2010) (131)
- The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice. (2010) (129)
- Effect of Cytokine Interplay on Macrophage Polarization during Chronic Pulmonary Infection with Cryptococcus neoformans (2011) (129)
- A Micro RNA Processing Defect in Rapidly Progressing Idiopathic Pulmonary Fibrosis (2011) (125)
- Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2. (2003) (125)
- Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung. (2009) (120)
- Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury. (2005) (119)
- Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus. (2008) (117)
- CCR2 Mediates Conventional Dendritic Cell Recruitment and the Formation of Bronchovascular Mononuclear Cell Infiltrates in the Lungs of Mice Infected with Cryptococcus neoformans12 (2008) (116)
- Impaired functional activity of alveolar macrophages from GM-CSF-deficient mice. (2001) (112)
- Role of Dendritic Cells and Alveolar Macrophages in Regulating Early Host Defense against Pulmonary Infection with Cryptococcus neoformans (2009) (112)
- Defective Phagocytosis and Clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation 1 (2003) (108)
- Macrophage inflammatory protein-1alpha (MIP-1alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection. (1997) (107)
- Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa. (2006) (107)
- The prognostic value of cardiopulmonary exercise testing in idiopathic pulmonary fibrosis. (2009) (107)
- CCR2 and CCR6, but Not Endothelial Selectins, Mediate the Accumulation of Immature Dendritic Cells within the Lungs of Mice in Response to Particulate Antigen12 (2005) (107)
- Distinct Roles for IL-4 and IL-10 in Regulating T2 Immunity during Allergic Bronchopulmonary Mycosis1 (2005) (106)
- Granulocyte-alveolar-macrophage interaction in the pulmonary clearance of Staphylococcus aureus. (1983) (104)
- The Role of Macrophage Inflammatory Protein-1α/CCL3 in Regulation of T Cell-Mediated Immunity to Cryptococcus neoformans Infection1 (2000) (103)
- Critical Role of Prostaglandin E2 Overproduction in Impaired Pulmonary Host Response following Bone Marrow Transplantation1 (2006) (100)
- Inability of human alveolar macrophages to stimulate resting T cells correlates with decreased antigen-specific T cell-macrophage binding. (1986) (96)
- Alterations in the pattern of arachidonate metabolism accompany rat macrophage differentiation in the lung. (1990) (94)
- Differentiation-related expression of ICAM-1 by rat alveolar epithelial cells. (1993) (92)
- Antigen presentation by guinea pig alveolar macrophages. (1981) (90)
- Course of FEV1 after Onset of Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients (2007) (89)
- Th2 but Not Th1 Immune Bias Results in Altered Lung Functions in a Murine Model of Pulmonary Cryptococcus neoformans Infection (2009) (89)
- Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: a prospective study in patients who failed to respond to corticosteroids. (2000) (89)
- The Gamma Interferon Receptor Is Required for the Protective Pulmonary Inflammatory Response to Cryptococcus neoformans (2005) (88)
- Generation of Antifungal Effector CD8+ T Cells in the Absence of CD4+ T Cells during Cryptococcus neoformans Infection1 (2005) (88)
- Inheritance of Immune Polarization Patterns Is Linked to Resistance versus Susceptibility to Cryptococcus neoformans in a Mouse Model (2008) (88)
- Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia (2010) (86)
- Langerhans cells: sentinels of skin associated lymphoid tissue. (1980) (86)
- Mononuclear cells in human lung parenchyma. Characterization of a potent accessory cell not obtained by bronchoalveolar lavage. (1987) (86)
- Cyclosporin A inhibits the growth of Cryptococcus neoformans in a murine model (1988) (86)
- Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages. (1989) (85)
- Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependent. (1999) (84)
- Sex differences in physiological progression of idiopathic pulmonary fibrosis (2008) (84)
- Effect of granulocyte-macrophage colony-stimulating factor on rat alveolar macrophage anticryptococcal activity in vitro. (1994) (83)
- Increased salivary elastase precedes gram-negative bacillary colonization in postoperative patients. (1987) (82)
- Latent herpesvirus infection augments experimental pulmonary fibrosis. (2010) (81)
- Interferon-γ Activates Rat Alveolar Macrophages for Anticryptococcal Activity (1991) (80)
- Role of granulocyte macrophage colony-stimulating factor in host defense against pulmonary Cryptococcus neoformans infection during murine allergic bronchopulmonary mycosis. (2007) (79)
- Interleukin-17 Drives Pulmonary Eosinophilia following Repeated Exposure to Aspergillus fumigatus Conidia (2012) (78)
- Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection. (2011) (74)
- Cysteinyl Leukotrienes Are Autocrine and Paracrine Regulators of Fibrocyte Function1 (2007) (74)
- Transient Neutralization of Tumor Necrosis Factor Alpha Can Produce a Chronic Fungal Infection in an Immunocompetent Host: Potential Role of Immature Dendritic Cells (2005) (74)
- Respiratory Disease in the Immunosuppressed Patient (1992) (74)
- Bronchoalveolar cells from sarcoid patients demonstrate enhanced antigen presentation. (1985) (74)
- Legionella pneumophila replicates within rat alveolar epithelial cells. (1993) (73)
- Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21 (2007) (73)
- Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia. (2008) (73)
- Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. (2006) (73)
- Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. (2004) (73)
- Role of natural killer cells in resistance to Cryptococcus neoformans infections in mice. (1987) (71)
- Natural killer cell function in human lung is compartmentalized. (1987) (66)
- Mesenchymal stromal cells in bronchoalveolar lavage as predictors of bronchiolitis obliterans syndrome. (2011) (66)
- Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neoformans. (1994) (64)
- Prognostic value of bronchiolitis obliterans syndrome stage 0-p in single-lung transplant recipients. (2005) (63)
- Regulatory Effects of Macrophage Inflammatory Protein 1α/CCL3 on the Development of Immunity to Cryptococcus neoformans Depend on Expression of Early Inflammatory Cytokines (2001) (63)
- Separation of Potent and Poorly Functional Human Lung Accessory Cells Based on Autofluorescence (1989) (60)
- Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect. (2004) (60)
- TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation (2008) (60)
- Depletion of murine CD8+ T cells in vivo decreases pulmonary clearance of a moderately virulent strain of Cryptococcus neoformans. (1993) (59)
- TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs. (2010) (58)
- Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute respiratory distress syndrome. (2006) (56)
- Augmented pulmonary IL-4 and IL-13 receptor subunit expression in idiopathic interstitial pneumonia (2004) (54)
- Ecological Succession of Bacterial Communities during Conventionalization of Germ-Free Mice (2012) (54)
- Immune enhancement of pulmonary clearance of nontypable Haemophilus influenzae (1988) (53)
- The role of methotrexate in the management of steroid-dependent asthma. (1994) (52)
- The role of C5 in polymorphonuclear leukocyte recruitment in response to Streptococcus pneumoniae. (1984) (51)
- Human pulmonary macrophages. Functional comparison of cells obtained from whole lung and by bronchoalveolar lavage. (1986) (50)
- Course of FEV(1) after onset of bronchiolitis obliterans syndrome in lung transplant recipients. (2007) (50)
- CD8 cells play a critical role in delayed type hypersensitivity to intact Cryptococcus neoformans. (1994) (50)
- Early Induction of CCL7 Downstream of TLR9 Signaling Promotes the Development of Robust Immunity to Cryptococcal Infection (2012) (50)
- Regulation of rat pulmonary dendritic cell immunostimulatory activity by alveolar epithelial cell-derived granulocyte macrophage colony-stimulating factor. (1995) (48)
- Langerhans cells: functional aspects revealed by in vivo grafting studies. (1980) (48)
- Obligatory role for interleukin-13 in obstructive lesion development in airway allografts. (2006) (48)
- Role of diminished epithelial GM-CSF in the pathogenesis of bleomycin-induced pulmonary fibrosis. (2000) (47)
- Pulmonary fibrosis induced by γ-herpesvirus in aged mice is associated with increased fibroblast responsiveness to transforming growth factor-β. (2012) (45)
- Mononuclear Cells From Human Lung Parenchyma Support Antigen‐Induced T Lymphocyte Proliferation (1989) (45)
- Treatment of murine cryptococcosis with cyclosporin-A in normal and athymic mice. (1989) (44)
- Workshop on idiopathic pulmonary fibrosis in older adults. (2010) (43)
- Urokinase is required for T lymphocyte proliferation and activation in vitro. (1999) (43)
- Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. (2004) (43)
- Leukocyte recruitment during pulmonary Cryptococcus neoformans infection. (2000) (42)
- Alveolar epithelial cells block lymphocyte proliferation in vitro without inhibiting activation. (1991) (42)
- Impaired synthesis of prostaglandin E2 by lung fibroblasts and alveolar epithelial cells from GM-CSF-/- mice: implications for fibroproliferation. (2003) (42)
- Modulation of the Pulmonary Type 2 T-Cell Response to Cryptococcus neoformans by Intratracheal Delivery of a Tumor Necrosis Factor Alpha-Expressing Adenoviral Vector (2007) (42)
- Influence of sample number and biopsy site on the histologic diagnosis of diffuse lung disease. (1995) (41)
- Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs (1985) (41)
- Focal interstitial CC chemokine receptor 7 (CCR7) expression in idiopathic interstitial pneumonia (2006) (40)
- Interferon-gamma activates rat alveolar macrophages for anticryptococcal activity. (1991) (40)
- Urokinase-Type Plasminogen Activator Is Required for the Generation of a Type 1 Immune Response to Pulmonary Cryptococcus neoformans Infection1 (2002) (39)
- Rapid diagnosis of community-acquired bacterial pneumonia. (1983) (38)
- Latent infection by γherpesvirus stimulates profibrotic mediator release from multiple cell types. (2011) (38)
- Regulation of alveolar epithelial cell ICAM-1 expression by cell shape and cell-cell interactions. (1994) (38)
- Interleukin 12: A Potential Link between Nerve Cells and the Immune Response in Inflammatory Disorders (1995) (37)
- Epithelial interactions and local engraftment of lung-resident mesenchymal stem cells. (2011) (37)
- Unusual numbers and distribution of Langerhans cells in skin with unique immunologic properties. (1980) (37)
- TLR9-induced interferon β is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis (2011) (36)
- Expression and functional implications of CCR2 expression on murine alveolar epithelial cells. (2004) (36)
- Pulmonary natural killer cell activity is reduced in patients with bronchogenic carcinoma. (1987) (36)
- Phenotypic and functional characterization of normal rat pleural macrophages in comparison with autologous peritoneal and alveolar macrophages. (1999) (36)
- Mechanisms of complement-mediated clearance of bacteria from the murine lung. (2015) (36)
- Southwestern Internal Medicine Conference: Nosocomial Pneumonia (1986) (35)
- CCL 18 as an Indicator of Pulmonary Fibrotic Activity in Idiopathic Interstitial Pneumonias and Systemic Sclerosis (2007) (35)
- Characterization of the production of monocyte chemoattractant protein-1 and IL-8 in an allogeneic immune response. (1993) (34)
- Androstenedione metabolism in human alveolar macrophages. (1983) (34)
- Early pulmonary granulocyte recruitment in response to Streptococcus pneumoniae. (1984) (34)
- Distinct compartmentalization of CD4+ T-cell effector function versus proliferative capacity during pulmonary cryptococcosis. (2006) (33)
- Low hospital mortality in patients with acute interstitial pneumonia. (2003) (33)
- Epithelial Interactions And Local Engraftment Of Lung-Resident Mesenchymal Stem Cells (2011) (31)
- Role and development of TH1/TH2 immune responses in the lungs. (2004) (31)
- Smoking-related idiopathic interstitial pneumonia (2014) (30)
- A morphological study of the role of phagocytes in the clearance of Staphylococcus aureus from the lung. (1983) (29)
- Differential regulation by leukotrienes and calcium of Fcγ receptor‐induced phagocytosis and Syk activation in dendritic cells versus macrophages (2006) (28)
- Effect of a CD4-Depleting Antibody on the Development of Cryptococcus neoformans-Induced Allergic Bronchopulmonary Mycosis in Mice (2006) (27)
- Impact of bacterial infections on airway diseases (2005) (27)
- Un vivo depletion of murine CD8 positive T cells impairs survival during infection with a highly virulent strain ofCryptococcus neoformans (2005) (26)
- A factor secreted by a human pulmonary alveolar epithelial-like cell line blocks T-cell proliferation between G1 and S phase. (1992) (25)
- CCR 2 Expression Determines T 1 Versus T 2 Polarization During Pulmonary Cryptococcus neoformans Infection 1 (2000) (25)
- Effect of systemic immunization on pulmonary clearance of Haemophilus influenzae type b (1985) (24)
- Determinants of bacterial clearance from the lower respiratory tract. (1986) (24)
- Diversity of the T-Cell Response to Pulmonary Cryptococcus neoformans Infection (2006) (24)
- Pulmonary clearance and phagocytic cell response to normal pharyngeal flora. (1981) (24)
- Mononuclear cells in exudative malignant pleural effusions. Characterization of pleural phagocytic cells. (1994) (24)
- Regulation of the immunostimulatory activity of rat pulmonary interstitial dendritic cells by cell-cell interactions and cytokines. (1994) (23)
- Multiple defects in arachidonate metabolism in alveolar macrophages from young asymptomatic smokers. (1989) (23)
- Paradoxical role of alveolar macrophage-derived granulocyte-macrophage colony-stimulating factor in pulmonary host defense post-bone marrow transplantation. (2008) (23)
- In vivo depletion of murine CD8 positive T cells impairs survival during infection with a highly virulent strain of Cryptococcus neoformans. (1994) (22)
- Tumor killing by human alveolar macrophages and blood monocytes. Decreased cytotoxicity of human alveolar macrophages. (1986) (22)
- Effect of primary immunization on pulmonary clearance of nontypable Haemophilus influenzae. (1989) (21)
- Cellular alterations in fibroproliferative lung disease. (1999) (21)
- The effects of systemic immunization of pulmonary clearance of Pseudomonas aeruginosa. (1985) (20)
- Pulmonary elastase activity in response to Streptococcus pneumoniae and Pseudomonas aeruginosa. (1985) (19)
- Immunologic Homeostasis during Infection: Coexistence of Strong Pulmonary Cell-Mediated Immunity to Secondary Cryptococcus neoformans Infection While the Primary Infection Still Persists at Low Levels in the Lungs1 (2006) (18)
- Pulmonary clearance of encapsulated and unencapsulated Haemophilus influenzae strains (1984) (18)
- Effect of laparotomy on clearance and cytokine induction in Staphylococcus aureus infected lungs. (2007) (17)
- Animal models for the study of noninvasive Haemophilus influenzae disease: pulmonary clearance systems. (1992) (16)
- Dual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lung. (2010) (14)
- Bone Marrow-Derived Cells in the Pathogenesis of Lung Fibrosis. (2005) (14)
- Invasive techniques in the diagnosis of bacterial pneumonia in the intensive care unit. (1990) (13)
- Reconstitution of a porin-deficient mutant of Haemophilus influenzae type b with a porin gene from nontypeable H. influenzae (1993) (12)
- NIH conference. Respiratory disease in the immunosuppressed patient. (1992) (12)
- Lung clearance of Staphylococcus aureus strains with differing protein A content: protein A effect on in vivo clearance (1978) (12)
- Nosocomial pneumonia in patients in intensive care units. (1985) (10)
- The fifth component of complement is not required for the clearance of Staphylococcus aureus. (1984) (10)
- Dendritic cells with a potent accessory activity are present in human exudative malignant pleural effusions. (1997) (9)
- Antigen Presentation by Alveolar Macrophages in Patients with Sarcoidosis a (1986) (9)
- Variable Prostaglandin E 2 Resistance in Fibroblasts from Patients with Usual Interstitial Pneumonia (2007) (8)
- Characteristics of alveolar macrophages in an animal model of resolving pulmonary inflammation. (1990) (8)
- Editorial Commentary: Methotrexate in Sarcoidosis (1990) (7)
- Bacterial species-dependent inhibition of human granulocyte elastase. (1988) (6)
- Tumor Necrosis Factor-α: A Multifaceted Mediator of Inflammation (1989) (6)
- Use of Antibiotics in Patients with Chronic Obstructive Pulmonary Disease (1986) (5)
- CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death. (2010) (5)
- Presence Of Right Ventricular Dysfunction Modifies Treatment Response To Sildenafil In The Step-IPF Trial (2011) (5)
- CD8 cells mediate delayed hypersensitivity following intrapulmonary infection with Cryptococcus neoformans. (1993) (5)
- Embryonic Mesodermal Origin Of Lung Resident Mesenchymal Stem Cells (LR-MSCs) And Their Role In Lung Repair And Fibrosis (2010) (4)
- Analysis Of The Microbiome Of The Normal And COPD Lung (2010) (4)
- Expression and functional implications of CCR 2 expression on murine alveolar epithelial cells (2003) (4)
- Chapter 11 – Macrophages (2009) (4)
- Nosocomial pneumonia. (1986) (4)
- Prognostic Value of Fibroblastic Foci in Patients With Usual Interstitial Pneumonia (2001) (3)
- Differential Roles of CC Chemokine Ligand (2002) (2)
- IL-12 is contained within sensory and sympathetic neurons in skin as well as central and peripheral glial cells (1995) (2)
- Cell-mediated immunity in the lung (2006) (2)
- Fluorescein Isothiocyanate-Induced Pulmonary Fibrosis Is Regulated by Monocyte Chemoattractant Protein-1 and Chemokine Receptor 2 (2001) (2)
- Increased Pulmonary Fibrosis In Aged Mice Infected With Murine Gammaherpesvirus When Compared To Young Controls (2010) (2)
- Human Pulmonary Macrophages (2015) (2)
- Characterization Of The Lung Microbiome Of Specific Pathogen-Free Mice With And Without Exposure To Cigarette Smoke In Vivo (2011) (2)
- Human Natural Killer Cells Enhance a Mixed Leukocyte Reaction (1988) (2)
- Pathogenesis and clinical features of pulmonary infections (1990) (2)
- Plasma Relaxin Predicts FVC in IPF. (2009) (2)
- Role of the polymorphonuclear leukocyte: Interaction with nosocomial pathogens (2005) (1)
- Bronchopulmonary Mycosis Macrophages during Allergic the Development of Alternatively Activated in Regulating T 2 Immunity and γ Role of IFN-Huffnagle (2005) (1)
- The role of antibiotics in treating acute exacerbations of COPD (1992) (1)
- Reply to DR. Wrench (1981) (1)
- PREDICTING IPF VS NSIP WITHOUT A SURGICAL LUNG BIOPSY (2007) (1)
- High-Throughput Plasma Biomarker Analysis In Ipf Reveals An Extracellular Matrix Remodeling Signature (2011) (1)
- Circulating Monocytes In Idiopathic Pulmonary Fibrosis (IPF) Patients Express TLR9 And CD206 (2011) (1)
- T Cell Proliferation via a Soluble MediatorInhibit Isolated from Human Lung Allografts Lung Resident Mesenchymal Stem Cells (2008) (1)
- Nosocomial pneumonia. (1987) (1)
- Fungal Interactions with Leukocytes (2006) (1)
- Longitudinal Changes In The Composite Physiologic Index And Pulmonary Function In Patients With Idiopathic Pulmonary Fibrosis And Emphysema (2010) (1)
- Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: A prospective study in patients who failed corticosteroids (1998) (1)
- INTERSTITIAL LUNG DISEASE | Idiopathic Pulmonary Fibrosis (2006) (1)
- Significance Of HCCL22 As A Biomarker In IPF (2010) (1)
- Idiopathic Pulmonary Fibrosis: Predicting Future Disease Course From Past Trends In Pulmonary Function (2011) (1)
- Infectionof Robust Immunity to Cryptococcal TLR9 Signaling Promotes the Development Early Induction of CCL7 Downstream of (2012) (0)
- Risk Factors For Pneumothorax During Transbronchial Biopsy In LPF: Lessons From The Comet Trial (2011) (0)
- Dendritic Cell Accumulation In Mice With Persistent Fungal Pneumonia Is Critically Dependent On The GM-CSF Induced Differentiation Of LY-6C(High) Monocytes Within The Lung (2011) (0)
- IL-17A Promotes Pulmonary DC And Macrophage Accumulation During The Transition From Th2 To Th1/Th17 Responses Following Repetitive Challenge With Aspergillus Fumigatus (2011) (0)
- Periostin: A Novel Protein Essential To The Development Of Pulmonary Fibrosis (2012) (0)
- in the Lungs Primary Infection Still Persists at Low Levels Infection While the Cryptococcus neoformans Cell-Mediated Immunity to Secondary Coexistence of Strong Pulmonary Immunologic Homeostasis during Infection: (2006) (0)
- Immune Reconstitution Disease In Crytococcus Neoformans-Infected Mice Associated With An Imbalance Between Inflammatory And Regulatory Cytokines (2011) (0)
- Relationship Between The Presence Of An Identifiable Antigen And Fibrosis At The Time Of Diagnosis Of Hypersensitivity Pneumonitis (2010) (0)
- High Resolution Computed Tomography (HRCT) as predictor of response and/or death in idiopathic pulmonary fibrosis (1996) (0)
- Identification Of Early (Dendritic Cell) And Late (CD4+ T Cell) Sources Of IL-10 Production In Mice With Persistent Cryptococcal Lung Infection (2012) (0)
- Accumulation of Inflammatory Lung Dendritic Cells Results from the CCR2-Mediated Recruitment of Ly6C-high/CD11b+ Monocytes. (2009) (0)
- Methotrexate in sarcoidosis. (1990) (0)
- Characterization of growth factor responsive lung antigen presenting cells (1996) (0)
- Expression of mRNA of co-stimulatory molecules B7-1 and B7- 2 in cultured rat pulmonary dendritic cells is enhanced by exposure to specific cytokines (1996) (0)
- Bone Marrow Transplantation in the Lung Following Pseudomonas aeruginosa Defective Phagocytosis and Clearance of (2017) (0)
- Bone Marrow Transplantation Pseudomonas aeruginosa in the Lung Following Defective Phagocytosis and Clearance of (2013) (0)
- Prospective Laboratory Evaluation For Collagen Vascular Disease In Patients Ultimately Diagnosed With Non-Specific Interstitial Pneumonia (2010) (0)
- TLR9 Facilitates Protective Immunity To Cryptococcus Neoformans By Supporting Early Production Of MCP3/5 And The Accumulation Of Ly6c+ Monocytes And DC In The Lungs (2011) (0)
- FibroblastsResults from Impaired Collagen Synthesis by IL-13-Deficient, but Not IL-4-Deficient, Mice Isothiocyanate-Induced Fibrosis in Protection from Fluorescein (2004) (0)
- pathogenesis of bleomycin-induced pulmonary fibrosis Role of diminished epithelial GM-CSF in the (2012) (0)
- Male Gender Is Associated with Pulmonary Hypertension in IPF. (2009) (0)
- Idiopathic Nonspecific Interstitial Pneumonia: Prognostic Value of Hallwalk Distance and Changes in Physiology. (2009) (0)
- 2 Prostaglandin E Changes Alter Fibroblast Responses to Bleomycin-Induced E Prostanoid Receptor (2005) (0)
- Infiltrates in the Lungs of Mice Infected with Bronchovascular Mononuclear Cell Recruitment and the Formation of CCR2 Mediates Conventional Dendritic Cell (2013) (0)
- Failed Containment Of Fungal Lung Infection In Gm-Csf Deficient Mice Is Associated With Impaired Accumulation And Differentiation Of Alveolar And Exudate Macrophages (2011) (0)
- Classically-activated CD11c+ CD11b+ Exudate Macrophages Are Derived From Recruited Ly6C-high CD11b+ Monocytes In The Lungs Of Mice With Fungal Pneumonia (2010) (0)
- High Resolution Computed Tomography And Surgical Lung Biopsy Findings Often Prompt Clinicians To Consider A Diagnosis Of Hypersensitivity Pneumonitis (2010) (0)
- Critical Role Of GM-CSF In The Local Differentiation Of CD11b+ Dendritic Cells And Exudate Macrophages From Ly-6C(High) Monocytes In Mice With Persistent Cryptococcal Lung Infection (2012) (0)
- Bone Marrow Transplantation in the Lung Following Pseudomonas aeruginosa Defective Phagocytosis and Clearance of and (2003) (0)
- Cryptococcus neoformans Immunity to Receptor 5 in Organ-Specific and Innate Cutting Edge : Role of C-C Chemokine (1999) (0)
- Mice in Response to Particulate Antigen Immature Dendritic Cells within the Lungs of Selectins , Mediate the Accumulation of CCR 2 and CCR 6 , but Not Endothelial Toews (2005) (0)
- Gammaherpesvirus-Infected Aged Mice Have Altered Fibroblasts And Epithelial Cells (2011) (0)
- Latent infection by (cid:1) herpesvirus stimulates profibrotic mediator release from multiple cell types (2011) (0)
- MIP-1α knockout mice develop a TH2 response following pulmonary Cryptococcus neoformans infection (1998) (0)
- TLR9 Signaling in Alveolar Epithelial Cells Protects from Gammaherpesvirus-Induced Apoptosis. (2009) (0)
- Prospectively Collected Antigen Exposures Do Not Differ Between Patients With Hypersensitivity Pneumonitis And Idiopathic Pulmonary Fibrosis (2011) (0)
- Lysophosphatidic Acid Induces Lung-Resident Mesenchymal Stem Cells Migration Through The Beta-Catenin Pathway (2011) (0)
- Prostaglandin E2as an Autocrine Inhibitor of Fibrotic Functions in Lung Resident Mesenchymal Stem Cells. (2009) (0)
- INTERPLAY OF CD40-DEPENDENT AND INDEPENDENT MECHANISMS IN THE PATHOGENESIS OF MURINE ALLERGIC BRONCHOPULMONARY MYCOSIS (2010) (0)
- Tumor necrosis factor-alpha. A multifaceted mediator of inflammation. (1989) (0)
- Urokinase-Type Plasminogen Activator Is Required for the Generation of a Type 1 Immune Response to Pulmonary Cryptococcus neoformans Infection 1 (2001) (0)
- The anti-fibrotic actions of plasminogen activation occur via upregulation of prostaglandin E2 synthesis in humans and mice (2010) (0)
- MonocyteshighDifferentiation of Ly-6 C from the CCR 2-Mediated Recruitment and Cells in Response to Fungal Infection Results Lung Dendritic + Accumulation of CD 11 b (2009) (0)
- Germ-Free Mice of Communities during Conventionalization Ecological Succession of Bacterial (2012) (0)
- T-Helper Cells and Host Defense to Cryptococcus neoformans in the Lung (1989) (0)
- Rationale and experimental support for cytokine therapy of fungal pneumonias. (2000) (0)
- Development of T 1 Immunity CCR 22 / Monocyte Chemotactic Protein-1 and Differential Roles of CC Chemokine Ligand (2002) (0)
- Dendritic Cells Derived From Recruited Ly6C-high Monocytes Promote T1 Immune Responses Within The Lungs Of Mice Infected With A Fungal Pathogen (2010) (0)
- Prostaglandin-Dependent Mechanism Pulmonary Fibrosis Via a GM-CSF Regulates Bleomycin-Induced (2013) (0)
- Bronchopulmonary Mycosis Regulating T2 Immunity during Allergic Distinct Roles for IL-4 and IL-10 in (2004) (0)
- Cryptococcus neoformans Infection Cells in the Absence of CD4+ T Cells during Generation of Antifungal Effector CD8+ T (2013) (0)
- Does the Composite Physiology Score Improve the Correlation to the Six Minute Walk Test over Individual Pulmonary Function Tests in Patients with Idiopathic Pulmonary Fibrosis (2009) (0)
- An Alternatively-Spliced Isoform Of Fibronectin As A Potential Biomarker In Idiopathic Pulmonary Fibrosis (2010) (0)
- TABLE 1. TREATMENT ADMINISTERED TO 99 PATIENTS WITH IDIOPATHIC USUAL INTERSTITIAL PNEUMONIA AND 9 PATIENTS WITH COLLAGEN VASCULAR DISEASE-ASSOCIATED USUAL INTERSTITIAL PNEUMONIA (2003) (0)
- Secondary Infections in Acute Lung Injury (1996) (0)
- Clinical And Radiologic Characterization Of Patients With Non-classifiable Interstitial Pneumonias (2010) (0)
- Transbronchial Biopsies Are A Reliable Source Of Lung Fibroblasts Following Shipment From Clinical Centers Across The USA (2012) (0)
- Rapid Communication Differentiation-related Expression of ICAM-l by Rat Alveolar (1993) (0)
- Chapter 10 – Macrophages (2002) (0)
- Change in the Composite Physiologic Index Predicts Mortality in Patients with IPF. (2009) (0)
- IL-17A Promotes Eosinophil Recruitment From Blood To Lung In Mice With Allergic Lung Disease Triggered By Repetitive Stimulation With Viable Aspergillus Fumigatus (2011) (0)
- Fibrocytes Are More Readily Detected In Lung Than Circulation Of IPF Patients (2012) (0)
- Cyclosporin A Inhibits theGrowthofCryptococcus neoformans ina MurineModel (1988) (0)
- Gender Differences In Pulmonary Hypertension In IPF: An Analysis Of The STEP-IPF Trial (2010) (0)
- Gammaherpesvirus Infection Augments Subsequent Fibrotic Responses Via the Recruitment of Fibrocytes and the Induction of Pro-Fibrotic Factors. (2009) (0)
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