Galit Lahav
#44,827
Most Influential Person Now
Israeli-American systems biologist
Galit Lahav's AcademicInfluence.com Rankings
Galit Lahavbiology Degrees
Biology
#1679
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#2743
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Systems Biology
#4
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#4
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Developmental Biology
#209
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#217
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Molecular Biology
#2664
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#2705
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Biology
Galit Lahav's Degrees
- PhD Molecular Biology Weizmann Institute of Science
- Bachelors Biology Tel Aviv University
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Why Is Galit Lahav Influential?
(Suggest an Edit or Addition)According to Wikipedia, Galit Lahav is an Israeli-American systems biologist and Professor of Systems Biology at Harvard Medical School. In 2018 she became Chair of the Department of Systems Biology at Harvard Medical School. She is known for discovering the pulsatile behavior of the tumor suppressor protein p53 and uncovering its significance for cell fate, and for her contributions to the culture of mentoring in science. She lives in Boston, Massachusetts.
Galit Lahav's Published Works
Published Works
- Dynamics of the p53-Mdm2 feedback loop in individual cells (2004) (1010)
- p53 Dynamics Control Cell Fate (2012) (643)
- Oscillations and variability in the p53 system (2006) (641)
- Encoding and Decoding Cellular Information through Signaling Dynamics (2013) (631)
- The multiple mechanisms that regulate p53 activity and cell fate (2019) (525)
- Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. (2008) (406)
- Cell Growth and Size Homeostasis in Proliferating Animal Cells (2009) (380)
- Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. (2012) (326)
- Stimulus-dependent dynamics of p53 in single cells (2011) (302)
- Basal Dynamics of p53 Reveal Transcriptionally Attenuated Pulses in Cycling Cells (2010) (243)
- Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing (2016) (238)
- The ups and downs of p53: understanding protein dynamics in single cells (2009) (231)
- Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction (2012) (213)
- Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle (2013) (207)
- Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. (2010) (193)
- Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins (2006) (144)
- High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis. (2013) (135)
- Cycling cancer persister cells arise from lineages with distinct programs (2021) (129)
- Distinct mechanisms act in concert to mediate cell cycle arrest (2009) (111)
- Activation and control of p53 tetramerization in individual living cells (2013) (98)
- Fourier analysis and systems identification of the p53 feedback loop (2010) (88)
- Oscillations by the p53-Mdm2 feedback loop. (2008) (87)
- Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest. (2018) (87)
- p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics (2017) (75)
- We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells. (2011) (72)
- p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM (2017) (68)
- Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit. (2016) (68)
- Stem cells: balancing resistance and sensitivity to DNA damage. (2014) (66)
- The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold (2013) (63)
- Schedule-dependent interaction between anticancer treatments (2016) (62)
- A synthetic–natural hybrid oscillator in human cells (2010) (61)
- The Strength of Indecisiveness: Oscillatory Behavior for Better Cell Fate Determination (2004) (57)
- Two is better than one; toward a rational design of combinatorial therapy. (2016) (40)
- Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages (2018) (39)
- Conservation and Divergence of p53 Oscillation Dynamics across Species. (2017) (36)
- Dynamics Control Cell Fate (2012) (34)
- The effect of dust storm particles on single human lung cancer cells. (2019) (31)
- A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest (2020) (25)
- Constant rate of p53 tetramerization in response to DNA damage controls the p53 response (2014) (24)
- A probabilistic approach to joint cell tracking and segmentation in high‐throughput microscopy videos☆ (2018) (24)
- p53 dynamics vary between tissues and are linked with radiation sensitivity (2021) (20)
- The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy (2020) (19)
- Single-cell analysis of circadian dynamics in tissue explants (2015) (18)
- Quantifying the Central Dogma in the p53 Pathway in Live Single Cells. (2020) (18)
- Cellular Conference Call: External Feedback Affects Cell-Fate Decisions (2006) (17)
- Leveraging and coping with uncertainty in the response of individual cells to therapy. (2018) (16)
- Dynamics of the DNA damage response: insights from live-cell imaging. (2013) (15)
- Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through Live-Cell Imaging and Modeling. (2019) (14)
- Cycling cancer persister cells arise from lineages with distinct transcriptional and metabolic programs (2020) (11)
- Decoding the insulin signal. (2012) (10)
- p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression (2016) (10)
- Identification of universal and cell-type specific p53 DNA binding (2020) (10)
- The puzzling interplay between p53 and Sp1 (2017) (9)
- Stereotyped p53 binding tuned by chromatin accessibility (2017) (7)
- How to survive and thrive in the mother-mentor marathon. (2010) (7)
- Fully unsupervised symmetry-based mitosis detection in time-lapse cell microscopy (2018) (5)
- A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest. (2020) (5)
- Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations (2022) (5)
- Principles, mechanisms and functions of entrainment in biological oscillators (2022) (3)
- Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest. (2019) (3)
- Connecting Timescales in Biology: Can Early Dynamical Measurements Predict Long-Term Outcomes? (2021) (3)
- Signal transduction and signaling networks (2013) (3)
- A multi-modal proteomics strategy for characterizing posttranslational modifications of tumor suppressor p53 reveals many sites but few modified forms (2018) (3)
- Preparing macrophages for the future (2021) (2)
- Identification of universal and cell-type specific p53 DNA binding (2019) (2)
- Louder for longer: Myc amplifies gene expression by extended transcriptional bursting. (2022) (1)
- Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages (2018) (1)
- Suppressing variation in synthetic circuits (2011) (1)
- The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold (2013) (1)
- Integrating genomic information and signaling dynamics for efficient cancer therapy. (2017) (1)
- Abstract LB-101: Combined p53 dynamics and post-translational modifications determine subsequent protein expression and cell fate (2019) (0)
- Determination The Strength of Indecisiveness : Oscillatory Behavior for Better Cell Fate (2004) (0)
- Keeping Up With Moving Targets: How Do Cancer Cells Switch In And Out Of Therapy-Resistant States? (2018) (0)
- Fluctuations in p 53 Signal ing Allow Escape from Cell-Cycle Arrest Graphical (0)
- Abstract 2159: Oscillating p53 temporal dynamics enable proliferative recovery of cells following DNA damage (2021) (0)
- Signal integration by a bHLH circuit enables fate choice in neural stem cells (2022) (0)
- Dynamics of the DNAdamage response: insights from live-cell imaging (2013) (0)
- Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction (2023) (0)
- Analysing protein post-translational modform regions by linear programming (2018) (0)
- Optimizing Radiation Fractionation Based on p53 Dynamics in Single Cells (2020) (0)
- Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability (2023) (0)
- Multi range ERK responses shape the proliferative trajectory of single cells following oncogene induced senescence (2022) (0)
- Reading oscillatory instructions: How cells achieve time-dependent responses to oscillating transcription factors. (2022) (0)
- The multiple mechanisms that regulate p53 activity and cell fate (2019) (0)
- The Single-Cell Yin and Yang of Live Imaging and Transcriptomics. (2017) (0)
- Morphology from Texture in Cytometry (2010) (0)
- Abstract 1851: Combined inhibition of PARP and the unfolded protein response synergistically reduces viability in BRCA1-mutant breast cancer cells (2018) (0)
- NPGRJ_NMETH_892 525..531 (2006) (0)
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