Garry Nolan
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American pathologist
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Biology
Garry Nolan's Degrees
- PhD Immunology Stanford University
- Bachelors Biology University of California, Berkeley
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Why Is Garry Nolan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Garry P. Nolan is an American immunologist, academic, inventor, and business executive. He holds the Rachford and Carlota A. Harris Professor Endowed Chair in the Department of Pathology at Stanford University School of Medicine. Nolan founded biotechnology companies, wrote numerous medical research papers, and has been active in ufology.
Garry Nolan's Published Works
Published Works
- Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum (2011) (2059)
- Production of high-titer helper-free retroviruses by transient transfection. (1993) (1756)
- Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data (2005) (1633)
- Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis (2015) (1454)
- viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia (2013) (1395)
- The Human Cell Atlas (2017) (1285)
- Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. (1996) (886)
- Extracting a Cellular Hierarchy from High-dimensional Cytometry Data with SPADE (2011) (884)
- Mass Cytometry: Single Cells, Many Features (2016) (813)
- Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development (2014) (787)
- Multiplexed ion beam imaging of human breast tumors (2014) (729)
- Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal (1990) (705)
- Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells (2004) (705)
- Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging (2017) (681)
- Three-dimensional intact-tissue sequencing of single-cell transcriptional states (2018) (678)
- A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites (2017) (617)
- Computational solutions to large-scale data management and analysis (2010) (610)
- Systemic Immunity Is Required for Effective Cancer Immunotherapy (2017) (594)
- A deep profiler's guide to cytometry. (2012) (591)
- NF-AT components define a family of transcription factors targeted in T-cell activation (1994) (584)
- Intracellular phospho‐protein staining techniques for flow cytometry: Monitoring single cell signaling events (2003) (577)
- Normalization of mass cytometry data with bead standards (2013) (568)
- Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. (2012) (546)
- DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide (1991) (524)
- Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling (2006) (500)
- Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators (2012) (483)
- The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. (1993) (453)
- Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ. (1988) (441)
- Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm (2015) (399)
- Automated identification of stratifying signatures in cellular subpopulations (2014) (391)
- High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. (1998) (388)
- Applications of retrovirus-mediated expression cloning. (1996) (372)
- Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. (1992) (365)
- MIFlowCyt: The minimum information about a flow cytometry experiment (2008) (362)
- Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. (2004) (348)
- Rapid Production of Retroviruses for Efficient Gene Delivery to Mammalian Cells Using 293T Cell–Based Systems (1999) (344)
- Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. (2010) (338)
- The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. (1997) (326)
- The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. (1993) (325)
- Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3 (1997) (320)
- An immune clock of human pregnancy (2017) (318)
- Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma (2020) (315)
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons (2011) (308)
- Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast (2010) (302)
- Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry (2002) (297)
- Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. (1990) (291)
- Automated Mapping of Phenotype Space with Single-Cell Data (2016) (280)
- Clinical recovery from surgery correlates with single-cell immune signatures (2014) (279)
- Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis (1997) (279)
- Mapping normal and cancer cell signalling networks: towards single-cell proteomics (2006) (270)
- NF-κB to the rescue: RELs, apoptosis and cellular transformation (1999) (268)
- Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states (2017) (267)
- The human body at cellular resolution: the NIH Human Biomolecular Atlas Program (2019) (265)
- The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner (1993) (255)
- Highly multiplexed simultaneous detection of RNAs and proteins in single cells (2016) (255)
- Efficient screening of retroviral cDNA expression libraries. (1995) (251)
- Chemical combination effects predict connectivity in biological systems (2007) (248)
- Host Control of HIV-1 Parasitism in T Cells by the Nuclear Factor of Activated T Cells (1998) (244)
- Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. (2008) (243)
- Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. (1998) (240)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- Wnt signaling is required for thymocyte development and activates Tcf‐1 mediated transcription (2001) (229)
- Chemical labeling strategies for cell biology (2006) (219)
- The transcriptional landscape of αβ T cell differentiation (2013) (214)
- High-content single-cell drug screening with phosphospecific flow cytometry. (2008) (212)
- Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front (2019) (212)
- Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front (2020) (207)
- Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models (2018) (205)
- An interactive reference framework for modeling a dynamic immune system (2015) (201)
- Conditional density-based analysis of T cell signaling in single-cell data (2014) (200)
- From single cells to deep phenotypes in cancer (2012) (200)
- Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide. (1997) (198)
- High‐Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization (2017) (197)
- Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette. (1996) (196)
- Single‐cell mass cytometry adapted to measurements of the cell cycle (2012) (196)
- Improved FACS-Gal: flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. (1991) (191)
- Single-cell mass cytometry for analysis of immune system functional states. (2013) (183)
- The inhibitory ankyrin and activator Rel proteins (1992) (182)
- A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. (2015) (180)
- A platinum‐based covalent viability reagent for single‐cell mass cytometry (2012) (175)
- ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs (2020) (170)
- Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. (2010) (160)
- MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure (2019) (157)
- B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression (2010) (157)
- The Initial Phase of an Immune Response Functions to Activate Regulatory T Cells1 (2009) (154)
- Coordinate Analysis of Murine Immune Cell Surface Markers and Intracellular Phosphoproteins by Flow Cytometry1 (2005) (153)
- Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1 (2003) (151)
- Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. (2016) (149)
- Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. (2006) (148)
- SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment (2021) (147)
- Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1 (2003) (140)
- Activation of the PKB/AKT pathway by ICAM-2. (2002) (133)
- Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry (2018) (133)
- Use of Escherichiu coli (E. coli) lacZ (β-Galactosidase) as a Reporter Gene. (1991) (131)
- Unifying mechanism for different fibrotic diseases (2017) (129)
- Generation of retroviral vector for clinical studies using transient transfection. (1999) (126)
- Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis (2018) (122)
- NF-AT-AP-1 and Rel-bZIP: Hybrid vigor and binding under the influence (1994) (122)
- Kinetics of B Cell Receptor Signaling in Human B Cell Subsets Mapped by Phosphospecific Flow Cytometry1 (2006) (118)
- Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors. (2000) (117)
- Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB (1999) (116)
- Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. (1990) (115)
- Targeting Rare Populations of Murine Antigen-Specific T Lymphocytes by Retroviral Transduction for Potential Application in Gene Therapy for Autoimmune Disease1 (2000) (115)
- Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice. (2001) (114)
- Luminescent imaging of β-galactosidase activity in living subjects using sequential reporter-enzyme luminescence (2006) (114)
- K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. (2007) (113)
- Characterization of the Murine Immunological Signaling Network with Phosphospecific Flow Cytometry1 (2005) (112)
- Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. (2003) (110)
- Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. (1996) (110)
- Analysis of Genomic Integrity and p53-Dependent G1Checkpoint in Telomerase-Induced Extended-Life-Span Human Fibroblasts (1999) (106)
- Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy (2018) (106)
- Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining (2014) (105)
- Flow cytometric analysis of kinase signaling cascades. (2004) (103)
- Early reprogramming regulators identified by prospective isolation and mass cytometry (2015) (102)
- Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide. (2001) (100)
- CODEX multiplexed tissue imaging with DNA-conjugated antibodies (2021) (99)
- Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. (2008) (99)
- A general approach for chemical labeling and rapid, spatially controlled protein inactivation. (2004) (98)
- Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer. (1996) (97)
- Fluorescent Cell Barcoding for Multiplex Flow Cytometry (2011) (97)
- Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race (2006) (95)
- Enabling Technologies for Personalized and Precision Medicine. (2020) (94)
- High-resolution myogenic lineage mapping by single-cell mass cytometry (2017) (94)
- Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back (2010) (94)
- NF-kappaB to the rescue: RELs, apoptosis and cellular transformation. (1999) (93)
- Visualization and cellular hierarchy inference of single-cell data using SPADE (2016) (92)
- Resistance is futile: assimilation of cellular machinery by HIV-1. (2001) (91)
- Phospho‐proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single‐cell level (2006) (91)
- Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. (1996) (88)
- DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide. (1991) (87)
- Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy. (2015) (87)
- Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse (2018) (87)
- Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. (1985) (86)
- Dominant effector genetics in mammalian cells (2001) (84)
- Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. (2014) (82)
- Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. (2007) (78)
- Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging (2021) (78)
- Cloud and heterogeneous computing solutions exist today for the emerging big data problems in biology (2011) (76)
- Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples. (2011) (76)
- Growth Inhibition and Apoptosis Due to Restoration of E2A Activity in T Cell Acute Lymphoblastic Leukemia Cells (1999) (75)
- Single‐Cell Phospho‐Protein Analysis by Flow Cytometry (2007) (74)
- Duration of antigen receptor signaling determines T-cell tolerance or activation (2010) (74)
- T-Cell Tropism and the Role of ORF66 Protein in Pathogenesis of Varicella-Zoster Virus Infection (2005) (73)
- Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery (2015) (72)
- What's wrong with drug screening today. (2007) (71)
- In vivo targeting of organic calcium sensors via genetically selected peptides. (2004) (71)
- The ERK Mitogen-Activated Protein Kinase Pathway Contributes to Ebola Virus Glycoprotein-Induced Cytotoxicity (2006) (69)
- Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. (1999) (69)
- Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus. (2015) (67)
- Involvement of Toso in activation of monocytes, macrophages, and granulocytes (2013) (66)
- Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells (2005) (64)
- Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry (2018) (64)
- Mass Cytometry Analysis Reveals Hyperactive NF Kappa B Signaling in Myelofibrosis and Secondary Acute Myeloid Leukemia (2016) (63)
- Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. (2007) (62)
- Generation of high-titer, helper-free retroviruses by transient transfection. (1997) (61)
- Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML. (2012) (61)
- A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes (2016) (60)
- Single‐Cell Phospho‐Protein Analysis by Flow Cytometry (2007) (59)
- Expression of Rho GTPases using retroviral vectors. (2000) (59)
- LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells. (2004) (59)
- NF-kappa B homodimer binding within the HIV-1 initiator region and interactions with TFII-I. (1996) (57)
- Proteomics and genomics: The emergent properties of biomarkers in mechanism and medicine (2006) (57)
- Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. (1999) (57)
- Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection (2019) (56)
- Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. (2011) (55)
- The Human Cell Atlas White Paper (2018) (55)
- Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line (2020) (55)
- Towards program optimization through automated analysis of numerical precision (2010) (55)
- Treatment of Autoimmune Disease by Adoptive Cellular Gene Therapy (2003) (55)
- Expression vectors and delivery systems. (1998) (55)
- Evolution of peptides that modulate the spectral qualities of bound, small-molecule fluorophores. (1998) (54)
- Retroviral delivery of peptide modulators of cellular functions. (2000) (54)
- Gene therapy progress and prospects: Novel gene therapy approaches for AIDS (2005) (53)
- Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy (2015) (53)
- Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice (2014) (53)
- Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17 (2015) (53)
- Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis. (2017) (51)
- Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity (2020) (50)
- Joint Modeling and Registration of Cell Populations in Cohorts of High-Dimensional Flow Cytometric Data (2013) (49)
- Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma (2020) (49)
- Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes (2015) (48)
- Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics (2020) (47)
- Complex Mammalian-like Hematopoietic System Found in a Colonial Chordate (2018) (47)
- A comprehensive atlas of immunological differences between humans, mice and non-human primates (2019) (47)
- Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients. (2017) (46)
- Whole animal cell sorting of Drosophila embryos. (1991) (46)
- Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma (2020) (45)
- Electron microscopy localization and characterization of functionalized composite organic-inorganic SERS nanoparticles on leukemia cells. (2008) (45)
- Stage Dependent Aberrant Regulation of Cytokine-STAT Signaling in Murine Systemic Lupus Erythematosus (2009) (43)
- Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008) (2009) (43)
- CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data (2012) (42)
- DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity (2018) (42)
- A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin (2001) (41)
- Implementing Mass Cytometry at the Bedside to Study the Immunological Basis of Human Diseases: Distinctive Immune Features in Patients with a History of Term or Preterm Birth (2015) (40)
- Proliferative tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells (2018) (40)
- Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. (1986) (40)
- A Novel Method for Detection of Phosphorylation in Single Cells by Surface Enhanced Raman Scattering (SERS) using Composite Organic-Inorganic Nanoparticles (COINs) (2009) (40)
- Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension (2017) (39)
- Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. (2010) (39)
- MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data. (2018) (38)
- Virtual and augmented reality for biomedical applications (2021) (38)
- Transcriptionally defective retroviruses containing lacZ for the in situ detection of endogenous genes and developmentally regulated chromatin. (1989) (38)
- Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy (2016) (38)
- Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging (2021) (37)
- Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. (2006) (37)
- Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry (2010) (36)
- Multiparameter Analysis of Intracellular Phosphoepitopes in Immunophenotyped Cell Populations by Flow Cytometry (2005) (36)
- Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity (2019) (36)
- Integration of mechanistic immunological knowledge into a machine learning pipeline improves predictions (2020) (36)
- Prolonged liver-specific transgene expression by a non-primate lentiviral vector. (2004) (35)
- mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function (2015) (35)
- Distinct signaling programs control human hematopoietic stem cell survival and proliferation. (2017) (34)
- Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1 (2002) (34)
- Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers (2020) (33)
- Structure learning in causal cyclic networks (2008) (33)
- The bcl-3 Proto-Oncogene Encodes a Nuclear IidB-Like Molecule That Preferentially Interacts with NF-KB p50 and p52 in a Phosphorylation-Dependent Manner (2003) (33)
- Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis (2003) (33)
- Statin-AE: A novel angiostatin–endostatin fusion protein with enhanced antiangiogenic and antitumor activity (2004) (31)
- Learning Signaling Network Structures with Sparsely Distributed Data (2009) (31)
- Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-Based Cell Targeting. (2015) (31)
- Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammation (2017) (31)
- Atomic mass tag of bismuth‐209 for increasing the immunoassay multiplexing capacity of mass cytometry (2017) (31)
- Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction (2020) (31)
- Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level. (2006) (30)
- The T Cell STAT Signaling Network Is Reprogrammed within Hours of Bacteremia via Secondary Signals1 (2009) (30)
- A Random Peptide Library Fused to CCR5 for Selection of Mimetopes Expressed on the Mammalian Cell Surface via Retroviral Vectors* (2005) (30)
- Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control (2019) (29)
- Antigen-Dependent Integration of Opposing Proximal TCR-Signaling Cascades Determines the Functional Fate of T Lymphocytes (2014) (29)
- Frontiers in cancer immunotherapy—a symposium report (2020) (29)
- Distinct Patterns of DNA Damage Response and Apoptosis Correlate with Jak/Stat and PI3Kinase Response Profiles in Human Acute Myelogenous Leukemia (2010) (28)
- Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data (2021) (27)
- Building a high-quality Human Cell Atlas (2021) (27)
- Role for polo-like kinase 4 in mediation of cytokinesis (2019) (27)
- Activation of the transcription factor NF-KB in GH3 pituitary cells (1994) (27)
- The Systemic Immune State of Super-shedder Mice Is Characterized by a Unique Neutrophil-dependent Blunting of TH1 Responses (2013) (26)
- SARS-CoV-2 infects human pancreatic b cells and elicits b cell impairment (2021) (26)
- New technologies for autoimmune disease monitoring (2010) (25)
- Single-Cell, Phosphoepitope-Specific Analysis Demonstrates Cell Type- and Pathway-Specific Dysregulation of Jak/STAT and MAPK Signaling Associated with In Vivo Human Immunodeficiency Virus Type 1 Infection (2008) (25)
- Flow cytometry in the post fluorescence era. (2011) (24)
- Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells (2020) (24)
- Harnessing Viral Devices as Pharmaceuticals: Fighting HIV-1's Fire with Fire (1997) (23)
- Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis. (2019) (23)
- Coordinate actions of innate immune responses oppose those of the adaptive immune system during Salmonella infection of mice (2016) (23)
- Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging (2021) (23)
- NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia. (2014) (23)
- Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice (2015) (22)
- Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry (2019) (22)
- An Updated Debarcoding Tool for Mass Cytometry with Cell Type-Specific and Cell Sample-Specific Stringency Adjustment (2017) (22)
- In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells (2017) (22)
- Landscape of coordinated immune responses to H1N1 challenge in humans. (2020) (22)
- A regression model approach to enable cell morphology correction in high-throughput flow cytometry (2011) (22)
- MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
- Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells. (2002) (21)
- CellSeg: a robust, pre-trained nucleus segmentation and pixel quantification software for highly multiplexed fluorescence images (2022) (21)
- GateFinder: projection-based gating strategy optimization for flow and mass cytometry (2018) (21)
- Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells (2002) (21)
- Profiling myelodysplastic syndromes by mass cytometry demonstrates abnormal progenitor cell phenotype and differentiation (2019) (21)
- Cardiac development: Transcription and the broken heart (1998) (20)
- Retroviral technology--applications for expressed peptide libraries. (2003) (20)
- SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages (2022) (20)
- The road ahead: Implementing mass cytometry in clinical studies, one cell at a time (2017) (19)
- High-throughput Bayesian network learning using heterogeneous multicore computers (2010) (19)
- Tissue schematics map the specialization of immune tissue motifs and their appropriation by tumors. (2021) (19)
- Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. (1987) (19)
- A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity. (1990) (19)
- Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery (2017) (19)
- Nonprimate lentiviral vectors. (2002) (19)
- The p65 subunit of NF-KB regulates IKB by two distinct mechanisms (2007) (18)
- Association of Reactive Oxygen Species-Mediated Signal Transduction with In Vitro Apoptosis Sensitivity in Chronic Lymphocytic Leukemia B Cells (2011) (18)
- T-cell STAT3 is required for the maintenance of humoral immunity to LCMV (2014) (17)
- Immunologic timeline of Ebola virus disease and recovery in humans. (2020) (17)
- Neurological, Cognitive, and Psychological Findings Among Survivors of Ebola Virus Disease From the 1995 Ebola Outbreak in Kikwit, Democratic Republic of Congo: A Cross-sectional Study (2018) (17)
- Deeper insights into hematological oncology disorders via single-cell phospho-signaling analysis. (2006) (17)
- Characterization of patient specific signaling via augmentation of bayesian networks with disease and patient state nodes (2009) (16)
- Single Cell Analysis and Selection of Living Retrovirus Vector-corrected Mucopolysaccharidosis VII Cells Using a Fluorescence-activated Cell Sorting-based Assay for Mammalian β-Glucuronidase Enzymatic Activity* (1999) (16)
- Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. (1996) (16)
- Induction of anti-tumor immunity in mice using a syngeneic endothelial cell vaccine. (2003) (16)
- Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades (2005) (16)
- Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19 (2021) (16)
- Multiplexed ion beam imaging ( MIBI ) of human breast tumors (2014) (16)
- Lentiviral vectors for the delivery of DNA into mammalian cells. (2004) (16)
- Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments (2022) (16)
- Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia (2018) (15)
- SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19 (2021) (15)
- Nomenclature of Toso, Fas Apoptosis Inhibitory Molecule 3, and IgM FcR (2015) (15)
- Neurotrophin dependence domain (2000) (15)
- Polyclonal antibodies to xenogeneic endothelial cells induce apoptosis and block support of tumor growth in mice. (2003) (15)
- Adjacent Cell Marker Lateral Spillover Compensation and Reinforcement for Multiplexed Images (2021) (15)
- Learning Cyclic Signaling Pathway Structures While Minimizing Data Requirements (2008) (15)
- ParaLearn: a massively parallel, scalable system for learning interaction networks on FPGAs (2010) (15)
- Identification of Novel LNK Mutations In Patients with Chronic Myeloproliferative Neoplasms and Related Disorders (2010) (14)
- SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming (2022) (14)
- Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes (2020) (14)
- Fluorescence-activated cell analysis and sorting of viable mammalian cells based on f 3-D-galactosidase activity after transduction of Escherichia coli lacZ ( reporter molecule / fluorescein digalactoside / retrovirus / promoter assay ) (14)
- Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis. (2018) (14)
- Annotation of Spatially Resolved Single-cell Data with STELLAR (2021) (14)
- Differential role of ICAM ligands in determination of human memory T cell differentiation (2007) (13)
- Mass cytometry to decipher the mechanism of nongenetic drug resistance in cancer. (2014) (13)
- High‐throughput precision measurement of subcellular localization in single cells (2017) (13)
- NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration. (2017) (13)
- Mass cytometry: The time to settle down (2017) (13)
- A Cancer Biologist's Primer on Machine Learning Applications in High-Dimensional Cytometry. (2020) (13)
- FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets (2020) (13)
- A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates (2022) (12)
- COP9 Signalosome Component JAB1/CSN5 Is Necessary for T Cell Signaling through LFA-1 and HIV-1 Replication (2012) (12)
- Novel Hematopoietic Progenitor Populations Revealed by Direct Assessment of GATA1 Protein Expression and cMPL Signaling Events (2011) (12)
- Phospho-specific flow cytometry in drug discovery. (2005) (12)
- Inflammatory molecular endotypes of nasal polyps derived from Caucasian and Japanese populations (2021) (12)
- A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data. (2019) (12)
- A novel splice donor mutation in the thrombopoietin gene leads to exon 2 skipping in a Filipino family with hereditary thrombocythemia. (2011) (11)
- EBI3 regulates the NK cell response to mouse cytomegalovirus infection (2017) (11)
- Leonard A. Herzenberg 1931–2013 (2013) (10)
- Recombinant feline immunodeficiency virus vectors. Preparation and use. (2002) (10)
- Author response: The Human Cell Atlas (2017) (10)
- Single timepoint models of dynamic systems (2013) (10)
- Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity (2021) (10)
- High-Dimensional Single Cell Analysis (2014) (10)
- WebFlow: a software package for high-throughput analysis of flow cytometry data. (2009) (10)
- Local delivery of cytokines by retrovirally transduced antigen-specific TCR+ hybridoma cells in experimental autoimmune encephalomyelitis. (1998) (10)
- Flt 3 Y 591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p 53 (2006) (10)
- Scalable multi-sample single-cell data analysis by Partition-Assisted Clustering and Multiple Alignments of Networks (2017) (9)
- Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits phorbol myristoyl acetate-stimulated phospholipase D activity in C3H/10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesis. (2000) (9)
- Raman Labeled Nanoparticles: Characterization of Variability and Improved Method for Unmixing. (2012) (9)
- Cancer Center (2017) (9)
- Spatial epitope barcoding reveals clonal tumor patch behaviors (2021) (9)
- Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery (2022) (9)
- RACK1 regulates Ki‐Ras‐mediated signaling and morphological transformation of NIH 3T3 cells (2006) (8)
- TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis (2019) (8)
- Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers (2021) (8)
- Human influenza virus challenge identifies cellular correlates of protection for oral vaccination (2021) (8)
- SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia (2018) (8)
- Robust Single-cell Matching and Multi-modal Analysis Using Shared and Distinct Features Reveals Orchestrated Immune Responses (2021) (7)
- Virus-Dependent Immune Conditioning of Tissue Microenvironments (2021) (7)
- Nanoscopic subcellular imaging enabled by ion beam tomography (2021) (7)
- Variation of Immune Cell Responses in Humans Reveals Sex-Specific Coordinated Signaling Across Cell Types (2019) (7)
- Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA (2022) (7)
- Cell type-specific monoclonal antibody cross-reactivity screening in non-human primates and development of comparative immunophenotyping panels for CyTOF (2019) (7)
- In situ detection of transcriptionally active chromatin and genetic regulatory elements in individual viable mammalian cells. (1989) (7)
- Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics (2020) (6)
- Voices in methods development (2019) (6)
- High Resolution Single Cell Maps Reveals Distinct Cell Organization and Function Across Different Regions of the Human Intestine (2021) (6)
- Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells (2002) (6)
- Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis (2020) (6)
- One-Way Matching of Datasets with Low Rank Signals (2022) (6)
- Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA (2022) (5)
- Subcellular localization of drug distribution by super-resolution ion beam imaging (2019) (5)
- New Views of Old Proteins: Clarifying the Enigmatic Proteome (2021) (5)
- A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging (2022) (5)
- Multicellular modules as clinical diagnostic and therapeutic targets (2021) (5)
- Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation (2019) (4)
- Ion beam subcellular tomography (2019) (4)
- Snapin, Positive Regulator of Stimulation- Induced Ca2+ Release through RyR, Is Necessary for HIV-1 Replication in T Cells (2013) (4)
- Responses Across a Human Hematopoietic Continuum Single-Cell Mass Cytometry of Differential Immune and Drug (2011) (4)
- Growth Inhibition and Apoptosis Due to Restoration of E 2 A Activity in T Cell Acute Lymphoblastic Leukemia Cells (1999) (4)
- In situ detection of stage-specific genes and enhancers in B cell differentiation via gene-search retroviruses. (1991) (4)
- Dynamics of the Cutaneous T Cell Lymphoma Microenvironment in Patients Treated with Pembrolizumab Revealed By Highly Multiplexed Tissue Imaging (2019) (4)
- Innovative Technologies for Advancement of WHO Risk Group 4 Pathogens Research (2019) (4)
- Tadpoles by the tail (2005) (4)
- Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection (2021) (4)
- The Atacama skeleton (2018) (4)
- The Initial Phase of an Immune Response (2009) (4)
- JAK1 As a Convergent Regulator of Hematopoietic Stem Cell Function and Stress Hematopoiesis (2016) (3)
- Continuous visualization of differences between biological conditions in single-cell data (2018) (3)
- Surveying the Influenza-specific Cytotoxic T Cell Response in Humans and Mice Using Mass-cytometry (CyTOF) and Combinatorial Tetramer Staining (2010) (3)
- 712. High Capacity Screen To Select Optimal Pre-trans-splicing Molecules for Trans-splicing Applications|[ast]| (2004) (3)
- Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry (2018) (3)
- Meta-analysis of Cytometry Data Reveals Racial Differences in Immune Cells (2017) (3)
- Profiling antigen-specific T cell phenotypes with heavy metal labeled peptide-Major Histocompatibility Complex tetramers and single cell mass-spectroscopy (CyTOF) (65.40) (2011) (3)
- Phenotypic segregation of Aedes aegypti for immune antibacterial activity and resistance to filariae (1996) (3)
- NRASG 12 V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia (2014) (3)
- Author Correction: Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis (2020) (2)
- Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. (2009) (2)
- A real-time GPU-accelerated parallelized image processor for large-scale multiplexed fluorescence microscopy data (2022) (2)
- Complex mammalian-like haematopoietic system found in a colonial chordate (2018) (2)
- Highly multiplexed spatial profiling with CODEX: bioinformatic analysis and application in human disease (2022) (2)
- Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells (2019) (2)
- Nuclear reprogramming and the cancer genome (2013) (2)
- Multiparameter Flow Cytometric Analysis Reveals Aberrant Phosphorylation of a Network of Effector Molecules in Defined Populations of Kras Mutant Bone Marrow. (2005) (2)
- Single Cell Trajectory Detection Orders Hallmarks of Early Human B Cell Development (2012) (2)
- A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy (2023) (2)
- Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes (2022) (2)
- Dynamics of the Bone Marrow Microenvironment during Leukemic Progression Revealed By Codex Hyper-Parameter Tissue Imaging (2018) (2)
- Oligonucleotide-directed site-specific integration of high complexity libraries into ssDNA templates. (2004) (2)
- A Novel Assay for Juvenile Myelomonocytic Leukemia Based on Aberrant Signaling Networks Measured Via Phospho-Specific Flow Cytometry Reduces Diagnosis Time from Weeks to Days. (2007) (2)
- High-dimensional single cell analysis : mass cytometry, multi-parametric flow cytometry and bioinformatic techniques (2014) (2)
- K-Ras Expression Induces Hyperproliferation and Aberrant Signaling in Primary Hematopoietic Stem/Progenitor Cells (2006) (2)
- Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study (2020) (2)
- High-dimensional cytometry. Preface. (2014) (2)
- Subcortical Brain Morphometry Differences between Adults with Autism Spectrum Disorder and Schizophrenia (2022) (2)
- High-Dimensional Analysis of Intracellular Signaling and Dasatinib Inhibition In High-Risk Pediatric Leukemia by 31-Parameter Mass Cytometry (2010) (1)
- High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population (2016) (1)
- Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate (2017) (1)
- 233: Multiparametric high dimensional analysis of normal & VZV infected human tonsil T cells at a single cell resolution by mass cytometry (2013) (1)
- and progenitor compartments biochemical and functional heterogeneity in human hematopoietic stem Single-cell phospho-specific flow cytometric analysis demonstrates (2011) (1)
- Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation (2023) (1)
- Inner-outer beauty: DNA-binding surface tags as cellular barcodes (2013) (1)
- Robust single-cell matching and multimodal analysis using shared and distinct features (2023) (1)
- Signaling Diversity in Human Lymphoma B Cells and in Tumor Infiltrating T Cells Correlates with Follicular Lymphoma Patient Clinical Outcomes (2008) (1)
- From single cells to deep phenotypes (2012) (1)
- Molecular and biological analysis of human hematopoietic stem cells at single-cell resolution (2017) (1)
- A tissue atlas of ulcerative colitis to guide TNF inhibitor therapy (2021) (1)
- Electron Microscopy Characterization of Composite Organic-Inorganic Nanoparticles (COINs) as Raman Labels for Extra-cellular Analyses (2008) (1)
- Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities (2022) (1)
- A Framework for Meta-Analysis of Cytometry Data (2016) (1)
- Retroviral and lentiviral gene therapy for autoimmune disease. (2000) (1)
- A spatial map of human macrophage niches links tissue location with function (2022) (1)
- Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study (2021) (1)
- Correction to: Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study (2021) (1)
- Isotopically Encoded Nanotags for Multiplexed Ion Beam Imaging (2020) (1)
- SARS-CoV-2 entry factors are expressed in nasal, ocular, and oral tissues: implications for COVID-19 prophylaxes/therapeutics (2021) (1)
- Mass Cytometric Analysis of AML Stem and Early Progenitor Cells Reveals Karyotype and Genotype-Specific Immunophenotypes That May Represent Targets for Antibody-Directed Therapies (2014) (1)
- Single Cell Mass Cytometry Reveals Hyperactivated Signaling Networks in Myeloproliferative Neoplasms (2014) (1)
- CRRAO Advanced Institute of Mathematics, Statistics and Computer Science (AIMSCS) (2013) (1)
- A Profile of 648 Signaling Network Events Identifies Cell Subsets with Diverse, Abnormal Responses to Lymphocyte Stimuli within Follicular Lymphoma Tumors. (2007) (1)
- Mitogen-independent cell cycle progression in B lymphocytes (2019) (1)
- Abstract 2275: Individualized drug combination based on single-cell drug perturbations (2018) (1)
- Intracellular Combinatorial Chemistry with Peptides in Selection of Caspase-like Inhibitors (1998) (1)
- Single Cell Mass Cytometry of Dysregulated Signaling Networks in Myeloproliferative Neoplasms and Secondary Acute Myeloid Leukemia (2012) (1)
- Microsphere cytometry to interrogate microenvironment-dependent cell signaling. (2017) (1)
- A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity (1990) (1)
- Multiparameter flow cytometry analysis of opioid-mediated alteration of human immune signaling pathways: 9AP3-1 (2012) (1)
- Abstract A089: Multiparametric immunofluorescence analysis of the tumor microenvironment using CODEX (2016) (1)
- Analysis of signaling pathways in human T-cells using Bayesian network modeling of single cell data (2004) (1)
- One contribution of 11 to a Theme (2013) (1)
- Identification of a Novel Splice Donor Mutation In the Thrombopoietin Gene In a Philippine Family with Hereditary Thrombocythemia (2010) (1)
- Systematically defining murine immunity at the phenotypic and functional levels via mass cytometry (P3283) (2013) (1)
- bHLH transcription factors play a critical role in T cell development (1997) (1)
- Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia (2015) (1)
- Glucocorticoids Exert a Dual Role in B-Cell Acute Lymphoblastic Leukemia: Apoptosis and Differentiation of Early B-Cell Populations (2018) (1)
- Kinetic differences in the activation of CD4+ T cells during the initiation of tolerance and autoimmunity (99.50) (2009) (0)
- This information is current as in Patients Undergoing Surgery Arginine-Enriched Nutritional Intervention Deep Immune Profiling of an Angst and (2017) (0)
- Dimensionality Reduction Reveals Distinct Shapes of Normal and Malignant Hematopoietic Cell Populations (2012) (0)
- 837. Prolonged Gene Expression in Murine Salivary Glands Following FIV-Based Lentiviral Vector Transduction (2005) (0)
- High Dimensional Single-Cell Mass Cytometry Demonstrates Conserved Human Toll-Like-Receptor Activation Signatures (2014) (0)
- Systematic Discovery of Novel Multi-Target Therapies for Glioblastoma Multiforme (2006) (0)
- Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19 (2022) (0)
- Application of Mass Cytometry to Measure Proliferation During Normal and Malignant Hematopoietic Differentiation (2011) (0)
- Structure learning for biomolecular pathways containing cycles (2008) (0)
- in primary hematopoietic stem/progenitor cells expression induces hyperproliferation and aberrant signaling G12D K-Ras (2010) (0)
- Abstract PR14: Automatic identification of cell niches and immune interactions important for clinical outcomes using multiparameter imaging and deep neural networks (2016) (0)
- Commitment of mitosis in B cells: “before and after” (2017) (0)
- Abstract 239: Mutation of the inhibitory adaptor protein LNK drives potentiated JAK-STAT signaling in patients with JAK2 V617F-negative myeloproliferative neoplasms (2010) (0)
- Microarray and CyTOF Characterization of Plasmacytoid Dendritic Cell Subsets (2010) (0)
- Abstract 2313: Characterizing intratumoral cellular heterogeneity in human glioblastoma xenografts by 30+ parameter single-cell mass cytometry (2015) (0)
- Cell-type Specific Changes in Cytokine-STAT Signal Transduction Stage Systemic Lupus Erythematosus (2007) (0)
- Abstract SY14-01: 34+ parameter single-cell mass cytometry of differential immune and drug responses across healthy human hematopoiesis and related malignancies (2011) (0)
- Abstract SY35-02: Phenotypic heterogeneity and instability of human serous ovarian cancer tumor-initiating cells (2012) (0)
- Tu1165: THE IMMUNE CELL MICROENVIRONMENT IS DIFFERENTIALLY-ALTERED ACCORDING TO DIVERSE EPITHELIAL LANDSCAPES IN THE PROGRESSION TO CANCER IN BARRETT OESOPHAGUS (2022) (0)
- Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype (2022) (0)
- New Books (2004) (0)
- HIGH PERFORMANCE RECONFIGURABLE COMPUTING FOR LEARNING BAYESIAN NETWORKS WITH FLEXIBLE PARAMETRIZATION A DISSERTATION SUBMITTED TO THE DEPARTMENT OF ELECTRICAL ENGINEERING AND THE COMMITTEE ON GRADUATE STUDIES OF STANFORD UNIVERSITY IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR (2010) (0)
- FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets (2020) (0)
- Trajectories from Snapshots: Integrated proteomic and metabolic single-cell assays reveal multiple independent adaptive responses to drug tolerance in a BRAF-mutant melanoma cell line (2019) (0)
- Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity (2020) (0)
- Engineered virus targets HIV-infected cells: interview with Garry Nolan, Ph.D. Interview by John S. James. (1997) (0)
- Cellular Signaling Correlates for SARS-CoV-2 Infection (2021) (0)
- An interview with Garry Nolan, Ph.D. by Glaser Vicki. (2009) (0)
- Integration of spatial and single-cell data across modalities with weak linkage (2023) (0)
- 3202 – METABOLIC PROFILING OF MOUSE HEMATOPOIETIC STEM CELL SELF-RENEWAL AT SINGLE-CELL RESOLUTION (2022) (0)
- Correction to: Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study (2021) (0)
- SLE progression in human and murine SLE is accompanied by cell and pathway specific negative regulation of cytokine signal transduction (2008) (0)
- Fresh frozen tissue staining with CODEX tagged antibody panel v1 (2019) (0)
- Functional identification of genes inducing EGF independence of human mammary epithelial cells (2001) (0)
- Overcoming barriers to solid tumor immunotherapy using natural killer cell therapies designed to mimic intraepithelial group 1 innate lymphoid cells (2022) (0)
- FAST TRACK RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells (2006) (0)
- Single cell mass cytometry of human peripheral blood reveals an endogenous immune response to surgical trauma (P1144) (2013) (0)
- Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. (2021) (0)
- Rheumatoid arthritis and other inflammatory joint diseases (human studies) (PP-036) (2010) (0)
- A spatial map of human macrophage niches reveals context-dependent macrophage functions in colon and breast cancer (2023) (0)
- Abstract PD6-03: Spatio-molecular dissection of the breast cancer metastatic microenvironment (2022) (0)
- Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis (2020) (0)
- CODEX Oligo-labeled Antibody Conjugation v1 (2019) (0)
- Spatial omics representation and functional tissue module inference using graph Fourier transform (2023) (0)
- ARSR-S1-1 Keynote Lecture: COVID-19, Allergic rhinitis and asthma- epidemiology to molecular mechanisms (2021) (0)
- Author Correction: Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis (2020) (0)
- HTAPP_Multiplexed Ion Beam Imaging (MIBI) antibody panel v1 (2021) (0)
- CellSeg: a robust, pre-trained nucleus segmentation and pixel quantification software for highly multiplexed fluorescence images (2022) (0)
- CODEX panel antibody validation protocol v1 (0)
- Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes (2020) (0)
- Brief report Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms (2010) (0)
- Lymphocyte signaling (SY4-1) Chairpersons: Tomohiro Kurosaki, Doreen Cantrell (2010) (0)
- Abstract PR08: High-grade serous ovarian tumor cells modulate natural killer cells to create an immune-tolerant microenvironment (2020) (0)
- Phosphoinositide 3-Kinase p110δ Is Dispensable for HoxA9/Meis1 and MLL-AF9 Mediated Leukemogenesis. (2008) (0)
- Genetic selection and the lure of SIN (2001) (0)
- Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival (2021) (0)
- Cell Host & Microbe Alternate Mechanisms of Initial Pattern Recognition differences in cytokine production among strains (2010) (0)
- Specific or Nonspecific? There Is Very Little Light at the End of the Tunnel Reply (2016) (0)
- Molecular cloning ofLyt-2, amembraneglycoprotein marking a subset ofmouseTlymphocytes: Molecular homology toitshuman counterpart, Leu-2/T8, andtoimmunoglobulin variable regions (1985) (0)
- Visualizing Inside the Cell (2007) (0)
- Abstract SY19-03: Single-cell signaling and pathology in primary cell cancers for mechanism and diagnostics (2010) (0)
- 356 B 2 FIGURE 1 Fluorescein carrier Rhodamine Red carrier (2017) (0)
- Glucocorticoids-Resistant Leukemic B-Cells Undergo a Phenotypic Change That Increases Sensitivity to SRC/ABL Inhibition (2018) (0)
- Improved Relapse Prediction in Pediatric Acute Myeloid Leukemia By Deconvolving Lineage-Specific and Cancer-Specific Features in Single-Cell Data (2022) (0)
- Profiling Myelodysplastic Syndromes By Mass Cytometry Demonstrates Distinct Immunophenotypic Aberrancies in Stem and Progenitor Populations (2014) (0)
- Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry (2018) (0)
- phosphorylation-dependent manner. interacts with NF-kappa B p50 and p52 in a kappa B-like molecule that preferentially The bcl-3 proto-oncogene encodes a nuclear I (2014) (0)
- New technology in immunology (WS-063) Chairpersons: Hiroyuki Kishi, Christopher Parish (2010) (0)
- Abstract LB-33: Identification of two unrecognized acute myeloid leukemia (AML) subtypes based on cell by cell analysis of leukemic blasts (2012) (0)
- 180 T cell phenotype drives restructuring of tumor microenvironment to balance T cell longevity and tumor control: insights from multiplexed imaging and multi-scale agent based modeling (2021) (0)
- Inference engines for phospho-signaling networks, disease mechanism, and clinical outcome at the single cell level (2008) (0)
- Predictive models demonstrate age‐dependent association of subcortical volumes and cognitive measures (2022) (0)
- Abstract A32: Computational dissection of phenotypic and functional heterogeneity in acute myeloid leukemia. (2015) (0)
- Next-Generation Molecular Histology Using Highly Multiplexed Ion Beam Imaging (MIBI) of Breast Cancer Tissue Specimens for Enhanced Clinical Guidance (2015) (0)
- Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL (2015) (0)
- Barcoded dna for long range sequencing (2018) (0)
- Correlations between Apoptosis & PI3K Pathway Activity Biological Characterization of AML at the Single Cell Level Based on Response to DNA Damaging Agents (2010) (0)
- Abstract IA30: Towards rationale therapy: Dealing with intertumor and intratumor heterogeneity (2013) (0)
- Nucleic Acids Research Isolation and characterization of the gene for the marine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2 (2005) (0)
- Integration of Mechanistic Immunological Knowledge into a Machine Learning Pipeline Increases Predictive Power (2020) (0)
- Derangements in Cytokine-induced STAT Protein Phosphorylation in Human Systemic Lupus Erythematosus (2007) (0)
- Signaling and Immunophenotypic Diversity in Pediatric Acute Myeloid Leukemia As Defined by 31-Parameter Single-Cell Mass Cytometry (2011) (0)
- Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia (2013) (0)
- Iconographies supplémentaires de l'article : Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus (2015) (0)
- Structure Learning in Causal Cyclic Networks Munther A. Dahleh (0)
- A Systems Immunology Approach Identifies Cytokine-Induced STAT Signaling Pathways Critical to Rheumatoid Arthritis Disease Activity and Treatment Response (2019) (0)
- Single Cell Developmental Classification of B Cell Precursor Acute Lymphoblastic Leukemia (BCP ALL) Reveals Link Between Phenotype, Signaling, and Drug Response (2014) (0)
- Abstract 3178: Deep sequencing of immunophenotypically distinct subsets in acute myeloid leukemia reveals reservoirs of genetically distinct subclones along a conserved differentiation trajectory. (2013) (0)
- COP 9 signalosome component JAB 1 / CSN 5 is necessary for T cell signaling through LFA-1 and HIV-1 replication (2018) (0)
- Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry (2019) (0)
- Abstract 3307: Improved survival in AML by in vivo drug targeting of conserved regulatory pathways in phenotypically distinct tumor-initiating compartments (2012) (0)
- in primary hematopoietic stem/progenitor cells K-RasG12D expression induces hyperproliferation and aberrant signaling (2013) (0)
- Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells (2020) (0)
- Network-Based Discovery of Prognostic Markers in Pediatric AML by Multi-Dimensional Single Cell Mass Cytometry (2012) (0)
- Abstract B15: NRASG12V oncogene mediates self-renewal in a murine model of acute myelogenous leukemia (2014) (0)
- Abstract B6: Identification of novel mutations in the inhibitory adaptor protein LNK in patients with JAK2 V617F-negative and -positive chronic myeloproliferative neoplasms (2010) (0)
- Physioxia improves the selectivity of hematopoietic stem cell expansion cultures. (2023) (0)
- A robust and sensitive flow cytometric method for multiplex RNA in-situ hybridization analysis of blood cells using oligo probes and branched DNA based signal amplification (P3356) (2013) (0)
- Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9-Specified Gene Expression Signature (2012) (0)
- Organizing the Cellular and Molecular Heterogeneity in High Grade Serous Ovarian Cancer by Mass Cytometry (2013) (0)
- Abstract 1916: Robust pro-inflammatory cytokine secretion by tumor-infiltrating t cells despite altered Stat1/Stat3 signaling responses (2010) (0)
- Mass Cytometry Analysis Of Myelofibrosis and Secondary Acute Myeloid Leukemia Reveals Constitutive and Cytokine Induced Signaling Abnormalities With Differential Sensitivities To Ruxolitinib (2013) (0)
- Rapid, Sustained B Cell Receptor Signaling in Lymphoma B Cells Differs from Normal Signaling in Tumor Infiltrating Nonmalignant B Cells. (2005) (0)
- Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis (2018) (0)
- Altered T Cell Antigen-specific Receptor Signaling in Tumor Infiltrating T Cells in Follicular Lymphomas (2010) (0)
- Recovering Cyclic Causal Structure (2010) (0)
- MYC-induced lymphomagenesis Inhibition of HMGcoA reductase by atorvastatin prevents and reverses (2013) (0)
- Recognizing a something when your library sees it. (2002) (0)
- Targeting HMGcoA reductase for prevention of MYC expressing lymphoma. (2007) (0)
- Mass Cytometry Organizes the Heterogeneity of Pediatric B Cell Acute Lymphoblastic Leukemia (2011) (0)
- 110 Multiparameter tissue imaging reveals the cutaneous T cell lymphoma microenvironment in response to immunotherapy (2019) (0)
- Abstract 2693: Relapse in BCP-ALL predicted by activated signaling in pro-B cell subsets (2016) (0)
- Abstract 6585: Systems biology for investigating drug resistance mechanism of melanoma (2020) (0)
- Proteomics and genomics (2006) (0)
- Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors (2018) (0)
- Paper I WILD TYPE P53 IS EXPRESSED AND PHOSPHORYLATED IN LEUKEMIA CELLS WITH FLT3 Y591 AMPLIFICATION AND BCL-2 OVEREXPRESSION (2006) (0)
- Immunity to virus infection (excluding retroviruses) (PP-025) (2010) (0)
- Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) (2015) (0)
- Mass Cytometric Analysis of AML Stem and Early Progenitor Cells Reveals Karyotype and Genotype-Specific Cell Cycle Properties That Correlate with Known Responses to Chemotherapy (2014) (0)
- HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA. (2017) (0)
- 319 Analysis of complex datasets with descriptive and predictive models – application to biomolecular pathways (2010) (0)
- Single Cell Phospho-Flow Analysis of Cytokine Stimulation in Human Hematopoietic Progenitors Reveals That G-CSF Acts Directly On Human Hematopoietic Stem Cells. (2009) (0)
- Phospho-tuning immunity through Denisovan, modern human and mouse TNFAIP3 gene variants (2019) (0)
- a rel-Related Polypeptide (1991) (0)
- Pre-operative immune signatures correlate with recovery from surgical trauma (HUM1P.267) (2015) (0)
- Deep single-cell profiling of the systemic immune response to pregnancy Twenty-one pregnant women receiving routine antepartum care at (2017) (0)
- The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes (2023) (0)
- A single cell systems-based view of immunology and cancer (2014) (0)
- Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models (2018) (0)
- All Roads Lead to Rome: Phenotypic Channeling to Uniform Differentiation Structures from Diverse Leukemia Genotypes by Mass Cytometry (2013) (0)
- Longitudinal Clinical Phenotyping of Post COVID Condition in Mexican Patients Recovering from Severe COVID-19: A Prospective Cohort Study (2022) (0)
- via Secondary Signals Reprogrammed within Hours of Bacteremia The T Cell STAT Signaling Network Is (2009) (0)
- Oncogene Withdrawal Selectively Alters Phosphoprotein States and Shifts Differentiation Status In Myeloid Leukemia Subpopulations (2010) (0)
- Abstract 2083: Development of novel targeted adjuvant therapy for triple negative breast cancer (2017) (0)
- Peripheral T Cell Function Opposing Activities in Selection and Modulates Tolerance through mir-181a-1/b-1 (2015) (0)
- Inhibitory Molecule 3, and IgM FcR Nomenclature of Toso, Fas Apoptosis (2016) (0)
- Clinical Translation of a Prognostic Follicular Lymphoma Signaling Profile (2010) (0)
- Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour. (2012) (0)
- The Genotype and Phenotype (GAP) Registry: A National Resource for Studying Genetic Regulation of Immune Function in Normal Populations (2010) (0)
- Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry (2018) (0)
- STEM-22. Single-cell mass cytometry of human glioblastoma reveals phenotypic heterogeneity and distinct cell cycle and epigenetic states among glioma stem cells (2017) (0)
- F.99. Identification of Signaling Alterations in Rheumatoid Arthritis by Phospho-specific Flow Cytometry (2009) (0)
- In Reply. (2016) (0)
- Abstract IA-08: High parameter single cell analysis has driven deep understanding of immune processes (2021) (0)
- Abstract 6669: Cellular neighborhoods predict pembrolizumab response in cutaneous T cell lymphoma (2020) (0)
- Phospho Flow Cytometry: Single‐Cell Signaling Networks in Next‐Generation Drug Discovery and Patient Stratification (2010) (0)
- Abstract 3842: Identification of distinct apoptosis and myeloid signaling profiles within acute myeloid leukemia (AML) blast subpopulations (2010) (0)
- Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line (2020) (0)
- Lymphoid VDJ Recombinase Activity: Development of a Novel Fluorescence-Based Assay System (1989) (0)
- NRAS oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia (2014) (0)
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