Garth Cooper
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Biology researcher in New Zealand
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Biology
Garth Cooper's Degrees
- Bachelors Biology University of Auckland
- Masters Ecology Victoria University of Wellington
- PhD Marine Biology University of New Zealand
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Why Is Garth Cooper Influential?
(Suggest an Edit or Addition)According to Wikipedia, Garth James Smith Cooper is a New Zealand academic biochemist, and as of 2021 is a full professor at the University of Auckland. Early life Cooper is of Pākehā and Ngāti Māhanga Māori descent. He speaks English, but not Māori, as his Māori grandmother thought he should learn English. He received schooling in New Zealand. He studied at the University of Auckland starting in 1969, and gained a BSc in Chemistry and Biochemistry , a BSc in Human Biology and medical degrees .
Garth Cooper's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. (2003) (1218)
- Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. (1987) (1201)
- Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes. (1988) (540)
- Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro (1988) (486)
- Adiponectin Inhibits Cell Proliferation by Interacting with Several Growth Factors in an Oligomerization-dependent Manner* (2005) (387)
- Hydroxylation and Glycosylation of the Four Conserved Lysine Residues in the Collagenous Domain of Adiponectin (2002) (357)
- Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. (1988) (354)
- Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes* (2005) (336)
- ISLET AMYLOID FORMED FROM DIABETES-ASSOCIATED PEPTIDE MAY BE PATHOGENIC IN TYPE-2 DIABETES (1987) (324)
- Watching amyloid fibrils grow by time-lapse atomic force microscopy. (1999) (317)
- Amyloid fibril formation from full-length and fragments of amylin. (2000) (300)
- Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease. (1994) (299)
- Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. (2006) (282)
- Polymorphic fibrillar assembly of human amylin. (1997) (269)
- Robust Early Pregnancy Prediction of Later Preeclampsia Using Metabolomic Biomarkers (2010) (265)
- Post-translational Modifications of the Four Conserved Lysine Residues within the Collagenous Domain of Adiponectin Are Required for the Formation of Its High Molecular Weight Oligomeric Complex* (2006) (253)
- The aggregation potential of human amylin determines its cytotoxicity towards islet β‐cells (2006) (209)
- Induction of Insulin Resistance In Vivo by Amylin and Calcitonin Gene–Related Peptide (1990) (194)
- Circulating insulin levels are related to bone density in normal postmenopausal women. (1993) (184)
- Randomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men. (2003) (184)
- Proteomic analysis of the brain in Alzheimer’s disease: Molecular phenotype of a complex disease process (2001) (178)
- Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development. (2001) (162)
- Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide. (2004) (161)
- Co-secretion of amylin and insulin from cultured islet beta-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic agents. (1991) (157)
- Human Amylin Oligomer Growth and Fibril Elongation Define Two Distinct Phases in Amyloid Formation* (2004) (150)
- Regeneration of the heart in diabetes by selective copper chelation. (2004) (145)
- Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus. (1989) (142)
- Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. (1997) (131)
- Amylin stimulates osteoblast proliferation and increases mineralized bone volume in adult mice. (1995) (126)
- Full-length rat amylin forms fibrils following substitution of single residues from human amylin. (2003) (125)
- Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretion. (2001) (119)
- Comparison of the Effects of Calcitonin Gene‐Related Peptide and Amylin on Osteoblasts (1999) (113)
- Regional protein expression in human Alzheimer’s brain correlates with disease severity (2018) (112)
- Fibrillogenic Amylin Evokes Islet β-Cell Apoptosis through Linked Activation of a Caspase Cascade and JNK1* (2003) (109)
- Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. (2008) (108)
- Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder (2016) (104)
- Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes (2005) (103)
- Adrenomedullin: a hypotensive hormone in man. (1997) (100)
- A proteomic approach identifies early pregnancy biomarkers for preeclampsia: Novel linkages between a predisposition to preeclampsia and cardiovascular disease (2009) (97)
- Demonstration of a hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation: quantitative comparisons between the biology of copper and eight other nutritionally essential elements in normal and diabetic individuals. (2005) (95)
- Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats (2008) (94)
- Therapeutic Potential of Copper Chelation with Triethylenetetramine in Managing Diabetes Mellitus and Alzheimer’s Disease (2011) (90)
- Amyloid-like inclusions in Huntington’s disease (2000) (89)
- Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities (2009) (89)
- Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism (2006) (88)
- Human colostrum: Identification of minor proteins in the aqueous phase by proteomics (2006) (86)
- Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia (2000) (84)
- A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study (2009) (82)
- Characterization of bovine seminal plasma by proteomics (2006) (82)
- Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum (2004) (81)
- Preptin, another peptide product of the pancreatic beta-cell, is osteogenic in vitro and in vivo. (2007) (81)
- Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. (2008) (78)
- Hemodynamic, hormonal, and renal effects of adrenomedullin in conscious sheep. (1997) (77)
- Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. (2003) (77)
- A comparative proteome analysis of hippocampal tissue from schizophrenic and Alzheimer's disease individuals (1999) (76)
- Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice. (1998) (73)
- Lipid-lowering effects of a modified butter-fat: a controlled intervention trial in healthy men (2002) (73)
- Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes. (1999) (72)
- Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo. (1997) (71)
- Mice lacking the neuropeptide alpha-calcitonin gene-related peptide are protected against diet-induced obesity. (2010) (70)
- A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes (2008) (70)
- Metabolic Dysfunction Is Restricted to the Sciatic Nerve in Experimental Diabetic Neuropathy (2015) (70)
- Selective divalent copper chelation for the treatment of diabetes mellitus. (2012) (68)
- ULTRASTRUCTURAL EVIDENCE THAT APOPTOSIS IS THE MECHANISM BY WHICH HUMAN AMYLIN EVOKES DEATH IN RINm5F PANCREATIC ISLET β‐CELLS (2001) (67)
- Amylin injection causes elevated plasma lactate and glucose in the rat (1991) (67)
- Induction of apoptosis by human amylin in RINm5F islet β‐cells is associated with enhanced expression of p53 and p21WAF1/CIP1 (1999) (65)
- Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia (2016) (64)
- Increased Expression and Activation of c-Jun Contributes to Human Amylin-induced Apoptosis in Pancreatic Islet β-Cells (2002) (60)
- Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases (2017) (59)
- Identification of novel putative membrane proteins selectively expressed during adipose conversion of 3T3-L1 cells. (2002) (59)
- Thiol reducing compounds prevent human amylin‐evoked cytotoxicity (2005) (58)
- Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA) (2012) (58)
- Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia. (2017) (57)
- Fas-Associated Death Receptor Signaling Evoked by Human Amylin in Islet β-Cells (2008) (57)
- A potential role for adrenomedullin as a local regulator of bone growth. (2001) (56)
- Tetracycline Treatment Retards the Onset and Slows the Progression of Diabetes in Human Amylin/Islet Amyloid Polypeptide Transgenic Mice (2009) (55)
- Response to intravenous injections of amylin and glucagon in fasted, fed, and hypoglycemic rats. (1993) (55)
- Amylin secretion from the perfused pancreas: dissociation from insulin and abnormal elevation in insulin-resistant diabetic rats. (1991) (55)
- Proteomic characterization of human serum proteins associated with the fat‐derived hormone adiponectin (2006) (54)
- Altered Calcium Homeostasis Does Not Explain the Contractile Deficit of Diabetic Cardiomyopathy (2008) (53)
- Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation (2014) (53)
- Identification of elevated urea as a severe, ubiquitous metabolic defect in the brain of patients with Huntington's disease. (2015) (51)
- Proteins associated with immunopurified granules from a model pancreatic islet beta-cell system: proteomic snapshot of an endocrine secretory granule. (2009) (50)
- The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes. (2010) (48)
- Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats (2013) (46)
- Copper(II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments (2010) (46)
- The pathogenic mechanism of diabetes varies with the degree of overexpression and oligomerization of human amylin in the pancreatic islet β cells (2014) (46)
- Characterization of proteomic changes in cardiac mitochondria in streptozotocin‐diabetic rats using iTRAQ™ isobaric tags (2007) (45)
- The proteome of mesenteric lymph during acute pancreatitis and implications for treatment. (2009) (45)
- Role of Ca2+ in apoptosis evoked by human amylin in pancreatic islet beta-cells. (1999) (45)
- Combined Endopeptidase Inhibition and Adrenomedullin in Sheep With Experimental Heart Failure (2002) (45)
- Complex formation equilibria of Cu(II) and Zn(II) with triethylenetetramine and its mono- and di-acetyl metabolites. (2013) (44)
- 8–37h‐CGRP antagonizes actions of amylin on carbohydrate metabolism in vitro and in vivo (1991) (44)
- A Label-free Selected Reaction Monitoring Workflow Identifies a Subset of Pregnancy Specific Glycoproteins as Potential Predictive Markers of Early-onset Pre-eclampsia* (2013) (42)
- Determination of protein for studies of marine herbivory: a comparison of methods (2000) (42)
- Title The fat-derived hormone adiponectin alleviates alcoholic andnonalcoholic fatty liver diseases in mice (2003) (42)
- The role of amylin in the insulin resistance of non-insulin-dependent diabetes mellitus. (1990) (41)
- Hyperamylinemia, hyperinsulinemia, and insulin resistance in genetically obese LA/N-cp rats. (1992) (41)
- Dissociation of the effects of amylin on osteoblast proliferation and bone resorption. (1998) (41)
- Hemodynamic, hormonal, and renal effects of intracerebroventricular adrenomedullin in conscious sheep. (1998) (40)
- Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes (2014) (40)
- Integrin shedding as a mechanism of cellular adaptation during cardiac growth. (2003) (40)
- Molecular Changes Evoked by Triethylenetetramine Treatment in the Extracellular Matrix of the Heart and Aorta in Diabetic Rats (2006) (40)
- Amylin and insulin in rat soleus muscle: dose responses for cosecreted noncompetitive antagonists. (1992) (38)
- Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic β‐cells (2006) (37)
- Proteome map of the human hippocampus (1999) (37)
- Integrity of the Human Faecal Microbiota following Long-Term Sample Storage (2016) (37)
- Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. (2008) (36)
- Systemic administration of adrenomedullin(27-52) increases bone volume and strength in male mice. (2001) (36)
- Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts. (2009) (35)
- Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington's disease human brain. (2016) (35)
- Peroxovanadates have full insulin-like effects on glycogen synthesis in normal and insulin-resistant skeletal muscle. (1991) (35)
- A new strategy for MS/MS data acquisition applying multiple data dependent experiments on Orbitrap mass spectrometers in non-targeted metabolomic applications (2014) (35)
- Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo. (1997) (34)
- Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice. (1998) (34)
- Insulin and insulin antagonists evoke phosphorylation of P20 at serine 157 and serine 16 respectively in rat skeletal muscle (1999) (34)
- Quantitative proteomic profiling identifies new renal targets of copper(II)‐selective chelation in the reversal of diabetic nephropathy in rats (2009) (34)
- Systemic administration of a novel octapeptide, amylin-(1---8), increases bone volume in male mice. (2000) (34)
- Transcriptomic analysis of the cardiac left ventricle in a rodent model of diabetic cardiomyopathy: molecular snapshot of a severe myocardial disease. (2007) (33)
- Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. (2002) (33)
- Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease (2019) (33)
- Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3‐L1 adipocytes (2004) (33)
- Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment (2013) (32)
- The proteome of rodent mesenteric lymph. (2008) (32)
- CHANGES IN THE MESENTERIC LYMPH PROTEOME INDUCED BY HEMORRHAGIC SHOCK (2010) (31)
- Triethylenetetramine and Metabolites: Levels in Relation to Copper and Zinc Excretion in Urine of Healthy Volunteers and Type 2 Diabetic Patients (2007) (31)
- Spontaneous Diabetes in Hemizygous Human Amylin Transgenic Mice That Developed Neither Islet Amyloid nor Peripheral Insulin Resistance (2008) (30)
- Evidence that alpha-calcitonin gene-related peptide is a neurohormone that controls systemic lipid availability and utilization. (2008) (30)
- Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis (2019) (30)
- Alteration in phosphorylation of P20 is associated with insulin resistance. (2001) (29)
- No Evidence of an Effect of Alterations in Dietary Fatty Acids on Fasting Adiponectin Over 3 Weeks (2008) (29)
- Adiponectin Induces A20 Expression in Adipose Tissue to Confer Metabolic Benefit (2014) (29)
- Proteomic analysis of adipocyte differentiation: Evidence that α2 macroglobulin is involved in the adipose conversion of 3T3 L1 preadipocytes (2004) (29)
- Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice. (2017) (28)
- Reversal of diabetes‐evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)‐selective chelator (2007) (28)
- Replacement of the CysA7-CysB7 disulfide bond with a 1,2,3-triazole linker causes unfolding in insulin glargine. (2015) (28)
- Evidence that amylin stimulates lipolysis in vivo: a possible mediator of induced insulin resistance. (2001) (27)
- Is type 2 diabetes an amyloidosis and does it really matter (to patients)? (2010) (27)
- Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease. (2020) (26)
- Rat amylin-(8-37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats. (1997) (26)
- Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS). (2007) (26)
- Acute pancreatitis severity is exacerbated by intestinal ischemia-reperfusion conditioned mesenteric lymph. (2008) (26)
- Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease (2015) (25)
- Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori (2003) (25)
- Phosphorylation of P20 is associated with the actions of insulin in rat skeletal and smooth muscle. (1999) (23)
- Amylin and insulin co-replacement therapy for insulin-dependent (type I) diabetes mellitus. (1991) (22)
- Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis. (2011) (22)
- Adrenomedullin attenuates pressor response to angiotensin II in conscious sheep. (2000) (22)
- Pharmacokinetics, Pharmacodynamics, and Metabolism of Triethylenetetramine in Healthy Human Participants: An Open‐Label Trial (2010) (21)
- Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin. (2012) (21)
- Direct visualisation of peptide hormones in cultured pancreatic islet alpha- and beta-cells by intact-cell mass spectrometry. (2007) (20)
- Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides. (2012) (20)
- Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure. (2002) (20)
- Characterization of dicarboxylic salts of protonated triethylenetetramine useful for the treatment of copper-related pathologies (2007) (20)
- Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation (2019) (19)
- Aberrant Processing of Plasma Vitronectin and High-Molecular-Weight Kininogen Precedes the Onset of Preeclampsia (2009) (19)
- The amylin superfamily: a novel grouping of biologically active polypeptides related to the insulin A-chain. (1989) (18)
- Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation. (2015) (18)
- Adipose tissue and metabolic and inflammatory responses to stroke are altered in obese mice (2017) (18)
- Proteomic analysis of whey and casein proteins in early milk from the marsupial Trichosurus vulpecula, the common brushtail possum. (2007) (18)
- THE REDOX STATUS OF EXPERIMENTAL HEMORRHAGIC SHOCK AS MEASURED BY CYCLIC VOLTAMMETRY (2009) (17)
- Proteomic analysis of the human brain in Huntington's Disease indicates pathogenesis by molecular processes linked to other neurodegenerative diseases and to type-2 diabetes. (2013) (17)
- Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia (2021) (16)
- Mechanisms Underlying the Antidiabetic Activities of Polyphenolic Compounds: A Review (2021) (15)
- Redox status of acute pancreatitis as measured by cyclic voltammetry: Initial rodent studies to assess disease severity* (2008) (15)
- Ethnic disparity of pancreatic cancer in New Zealand (2002) (15)
- Transmural differences in respiratory capacity across the rat left ventricle in health, aging, and streptozotocin-induced diabetes mellitus: evidence that mitochondrial dysfunction begins in the subepicardium. (2011) (15)
- Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts. (2014) (15)
- Development and validation of a rapid HPLC method for the simultaneous determination of triethylenetetramine and its two main metabolites in human serum. (2007) (15)
- Dissociation of the effects of amylin on osteoblast proliferation and bone resorption. (1998) (15)
- Acute application of human amylin, unlike β‐amyloid peptides, kills undifferentiated PC12 cells by apoptosis (1997) (15)
- On the structure of the copper–amylin complex (2015) (14)
- Plasma Clusterin Increased Prior to Small for Gestational Age (SGA) Associated With Preeclampsia and Decreased Prior to SGA in Normotensive Pregnancies (2012) (14)
- Modelling atherosclerosis by proteomics: Molecular changes in the ascending aortas of cholesterol-fed rabbits. (2015) (14)
- Applied nutritional investigation Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-, and C-reactive protein to a high-fat dietary load (2008) (14)
- Shared perturbations in the metallome and metabolome of Alzheimer’s, Parkinson’s, Huntington’s, and dementia with Lewy bodies: A systematic review (2020) (14)
- Physicochemical studies on the copper(II) binding by glycated collagen telopeptides. (2015) (13)
- Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine. (2008) (12)
- Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis (2016) (12)
- Essential roles of insulin, AMPK signaling and lysyl and prolyl hydroxylases in the biosynthesis and multimerization of adiponectin (2015) (12)
- Illuminating the molecular basis of diabetic arteriopathy: A proteomic comparison of aortic tissue from diabetic and healthy rats (2010) (12)
- Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds. (2013) (11)
- α-Calcitonin gene related peptide (α-CGRP) mediated lipid mobilization in 3T3-L1 adipocytes (2014) (11)
- A simple and rapid method for identifying and semi-quantifying peptide hormones in isolated pancreatic islets by direct-tissue matrix-assisted laser desorption ionization time-of-flight mass spectrometry. (2011) (11)
- Restoration of myocellular copper-trafficking proteins and mitochondrial copper enzymes repairs cardiac function in rats with diabetes-evoked heart failure. (2019) (10)
- Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location. (2020) (10)
- Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase. (2006) (10)
- Probing the urinary proteome of severe acute pancreatitis. (2007) (10)
- Glicentin‐related pancreatic polypeptide inhibits glucose‐stimulated insulin secretion from the isolated pancreas of adult male rats (2015) (10)
- Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson’s Disease Dementia (2021) (9)
- Visceral Adiposity and Glucoregulatory Peptides are Associated with Susceptibility to Type 2 Diabetes: The TOFI_Asia Study (2020) (9)
- Plasma metals as potential biomarkers in dementia: a case–control study in patients with sporadic Alzheimer’s disease (2018) (9)
- Treatment of type 2 diabetes mellitus (1998) (8)
- Tissue-Specific Sample Dilution: An Important Parameter to Optimise Prior to Untargeted LC-MS Metabolomics (2019) (8)
- Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain (2020) (8)
- Metabolic effects of amylin in lactating goats. (1999) (8)
- A novel two-chain IGF-II-derived peptide from purified β-cell granules. (2010) (8)
- Complex formation equilibria of Cu2 + and Zn2 + with Irbesartan and Losartan (2017) (7)
- Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts (2013) (6)
- Abnormalities of selenium but not of copper homeostasis may drive tissue fibrosis in patients with systemic sclerosis. (2015) (6)
- Correction: Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities (2009) (6)
- Untargeted metabolomics reveals plasma metabolites predictive of ectopic fat in pancreas and liver as assessed by magnetic resonance imaging: the TOFI_Asia study (2021) (6)
- Amylin, Amyloid and Age-Related Disease (1996) (6)
- The novel hormone, preptin, is another bone-active product of the pancreatic beta-cell (2002) (6)
- Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency (2022) (5)
- Low-dose copper infusion into the coronary circulation induces acute heart failure in diabetic rats: New mechanism of heart disease. (2015) (5)
- Metabolomic signatures for visceral adiposity and dysglycaemia in Asian Chinese and Caucasian European adults: the cross-sectional TOFI_Asia study (2020) (5)
- A reappraisal of current hypotheses concerning the possible roles of amylin in physiology, pathology and therapeutics. (1995) (5)
- Impaired insulin secretion in perfused pancreases isolated from offspring of female rats fed a low protein whey-based diet. (2008) (5)
- Amylin evokes phosphorylation of P20 in rat skeletal muscle (1999) (5)
- Peripherally administered desacetyl alpha-MSH and alpha-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression. (2006) (4)
- Full-length ATP7B reconstituted through protein trans-splicing corrects Wilson disease in mice (2022) (4)
- Alteration in Phosphorylation of P 20 Is Associated With Insulin Resistance (2001) (4)
- Conversion of non-adipogenic fibroblasts into adipocytes by a defined hormone mixture. (2015) (4)
- Coordination of mammary metabolism and blood flow after refeeding in rats. (2009) (4)
- Severe and Regionally Widespread Increases in Tissue Urea in the Human Brain Represent a Novel Finding of Pathogenic Potential in Parkinson’s Disease Dementia (2021) (3)
- Identification and characterization of a bovine myosin light chain‐1 fast polymorphism (2001) (3)
- Amylin and adrenomedullin - novel promotors of osteoblast survival from apoptosis (2000) (3)
- Nucleotide sequence of a cDNA for canine amylin. (1992) (3)
- Widespread severe cerebral elevations of haptoglobin and haemopexin in sporadic Alzheimer's disease: Evidence for a pervasive microvasculopathy. (2021) (3)
- Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes. (1999) (3)
- A unique case of neural amyloidoma diagnosed by mass spectrometry of formalin-fixed tissue using a novel preparative technique (2011) (3)
- Synthesis of biologically active tritiated amylin and salmon calcitonin analogues. (2000) (3)
- Regional protein expression in human Alzheimer’s brain correlates with disease severity (2018) (3)
- Synthesis, crystal structure, and protonation behaviour in solution of the recently-discovered drug metabolite, N1,N10-diacetyltriethylenetetramine (2012) (3)
- Amylin and Related Proteins: Physiology and Pathophysiology (2011) (2)
- Pancreas Fat, an Early Marker of Metabolic Risk? A Magnetic Resonance Study of Chinese and Caucasian Women: TOFI_Asia Study (2022) (2)
- Peripherally administered desacetyl α-MSH and α-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression (2006) (2)
- GSK3 involvement in amylin signaling in isolated rat soleus muscle (2004) (2)
- Role of Ca2+ in apoptosis evoked by human amylin in pancreatic islet β-cells (1999) (2)
- Altered metabolic gene expression in the brain of a triprolyl-human amylin transgenic mouse model of type 2 diabetes (2019) (2)
- Incorporation of 'click' chemistry glycomimetics dramatically alters triple-helix stability in an adiponectin model peptide. (2017) (2)
- Expedient Synthesis of Peptides Containing N ε-Carboxymethyllysine (2014) (2)
- Hepatocyte nuclear factor 1 negatively regulates amylin gene expression. (2003) (2)
- Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin. (2015) (2)
- Protein concentration in the rat maternal diet programs appetite and glucose metabolism in the offspring (2003) (2)
- Severe and regionally-widespread increases in tissue urea in the human brain represent a novel finding of pathogenic potential in Parkinson’s disease dementia (2021) (1)
- Amylin evokes protein p20 phosphorylation and insulin resistance in rat skeletal muscle extensor digitorum longus (2002) (1)
- Low Energy Diet-induced and Bariatric Surgery-induced Weight Loss Decreases Branched-chain and Aromatic Amino Acids in Plasma and Tissue (P21-078-19). (2019) (1)
- Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization (2021) (1)
- Reversal of diabetes-evoked changes in cardiac function by treatment with a copper (II)-Selective chelator (2009) (1)
- Hyperglycemia-induced disorder of cardiac copper regulation is a newly-recognised mechanism of left ventricular disease in diabetes (2006) (1)
- Proteomic Analysis of the Pancreatic Islet β-Cell Secretory Granule : Current Understanding and Future Opportunities (2011) (1)
- Effect of intravenous injections of amylin in the fasted, anaesthetized rat. (1991) (1)
- Glucoregulatory activity of vesiculin in insulin sensitive and resistant mice (2019) (1)
- Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice (2016) (1)
- Effects of rat calcitonin-gene-related peptide-1 on cyclic AMP levels in skeletal muscle of the rat (1989) (1)
- Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin (2020) (1)
- Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA) (2012) (1)
- Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/hIAPP transgenic mice Running title: Tetracycline suppresses diabetes in hA/hIAPP transgenic mice (2009) (1)
- A Multi-Omic Huntington’s Disease Transgenic Sheep-Model Database for Investigating Disease Pathogenesis (2021) (1)
- Therapeutic Potential of Human Amylin Analogues in Diabetes Mellitus (1998) (1)
- Contrasting Sodium and Potassium Perturbations in the Hippocampus Indicate Potential Na+/K+-ATPase Dysfunction in Vascular Dementia (2022) (1)
- Glycation as an atherogenic modification of lipoproteins, and the contribution of copper (2015) (0)
- Improved cardiac function in diabetic rats following treatment with a selective copper (II) chelator (2009) (0)
- 187 Mitochondrial Dysfunction in the Diabetic Heart — Imbalance in Fusion/Fission Axis? (2016) (0)
- 3,12-Diaza-6,9-diazonia-2,13-dioxotetradecane bis(perchlorate) (2012) (0)
- Understanding the placental mechanisms underpinning increased fetal growth in a mouse model of FGR following sildenafil citrate treatment: Insight from network analyses (2015) (0)
- Dosage de l'activite de l'amyline (1992) (0)
- Direct detection of peptide hormones from single pancreatic islets using MALDI-TOF MS (2011) (0)
- Proteomic AnalysisProteomic analysis of the Pancreatic Islet β-Cellpancreatic islet β-cell Secretory Granulesecretory granule : Current Understanding and Future Opportunities (2011) (0)
- Crystal structure of mouse myo-inositol oxygenase in complex with substrate (2006) (0)
- Role of amylin in the regulation of energy metabolism in health and disease (1995) (0)
- TETA, A Selective Cu2+ Chelator, Prevents Neurovascular Injury In Streptozotocin-Induced Diabetic Rats (2011) (0)
- Treatment of oevervikt Science essentiellt hoegt blood pressure is samt liknande sjukdomar. (1991) (0)
- BS4-A Applications of proteomics in diabetes: route to new and improved understanding of disease mechanisms and the generation of new therapeutic approaches (2008) (0)
- Diabetes-evoked pathogenic changes associated with altered copper uptake/transport pathways in the aorta of STZ-diabetic rats: Effects of treatment by Cu(II)-selective chelation (2013) (0)
- Illuminating the molecular basis of diabetic arteriopathy: A proteomic comparison of aortic tissue from diabetic and healthy rats (2010) (0)
- Prevention and / or treatment of cardiovascular disease and / or heart failure associated (2003) (0)
- Use of an amylin antagonist in the preparation of a medicament for the treatment of obesity and hypertension and disorders associated intrinsic. (1990) (0)
- Do anti-diabetic drugs act as copper ligands? (2013) (0)
- Fates intertwined (2006) (0)
- P67-S The Insulin Granule: Probing Intracellular Post-Translational Proteolysis. (2007) (0)
- Effects of STZ-induced diabetes on contraction and Ca2+ transient in rat left ventricular trabeculae (2007) (0)
- Upregulation of mitofusin-2 - friend or foe to the diabetic heart? (2016) (0)
- A natural butterfat that elicits clinically significant lowering of total- and LDL-cholesterol when added to the diet of normal men : a novel route to decreasing cardiovascular risk in human populations? (2001) (0)
- Pancreatic proglucagon products as unexpected modulators of insulin secretion (2013) (0)
- Impaired insulin secretion in perfused pancreases isolated from offspring of protein malnourished rats (2006) (0)
- inhibits proliferation of osteoblasts and chondrocytes Trifluoroacetate, a contaminant in purified proteins, (2016) (0)
- Synthesis of Glycosylated 5‐Hydroxylsine, an Important Amino Acid Present in Collagen‐Like Proteins such as Adiponectin. (2012) (0)
- 249 The Role of Selenium Deficiency in the Pathogenesis of Systemic Sclerosis (2016) (0)
- Adiponectin induces A20 expression to confer metabolic benefit (2014) (0)
- Adiponectin induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages (2013) (0)
- Comparison of the effects of food deprivation and insulin on the synthesis of proteins in mammary cells (2010) (0)
- Cardiac function and fat composition in STZ-induced diabetic rats (2009) (0)
- Using an amylin antagonist for the manufacture of a Artzneimittels for the treatment of obesity and essential hypertension and related diseases. (1990) (0)
- Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy (2011) (0)
- T1829 The Proteome of Mesenteric Lymph During Acute Pancreatitis and Implications for Treatment (2009) (0)
- Agents hypoglycemiques ameliores (1991) (0)
- Aktivätsmessungen of amylin (1992) (0)
- Title Harmine Induces Adipocyte Thermogenesis through RAC 1-MEK-ERK-CHD 4 Axis (2016) (0)
- Regulation of copper metabolism in the diabetic retina and effects of treatment with the Cu(II) chelator triethylenetetramine (TETA) (2016) (0)
- Human opticin reduces pathological preretinal neovascularization in the mouse model of oxygen-induced retinopathy. (2017) (0)
- Role of a newly discovered pancreatic peptide in the control of insulin secretion (2012) (0)
- Photographs and Memories: As Snapshot of Cultured Endocrine Cells (2008) (0)
- Amylin stimulates bone growth in experimental animals. (1995) (0)
- A process for the preparation of amylin antagonists (1995) (0)
- Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes (2021) (0)
- W2018 Proteomic Changes in Mesenteric Lymph Secondary to Haemorrhagic Shock (2009) (0)
- Altered metabolic gene expression in the brain of a triprolyl-human amylin transgenic mouse model of type 2 diabetes (2019) (0)
- Abstract LB-287: Spermidine/spermine actyltransferase is responsible for the metabolism of triethylenetetramine and other polyamine analogs in humans (2010) (0)
- Impaired mitochondrial copper transport in diabetic cardiomyopathy: Mechanism and treatment with Cu(II) chelation by triethylenetetramine (TETA) (2016) (0)
- Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts (2013) (0)
- Purification andcharacterization ofapeptide fromamyloid-rich pancreases oftype2diabetic patients (1987) (0)
- Dissecting the relationship between plasma and tissue metabolome in a cohort of women with obesity: Analysis of subcutaneous and visceral adipose, muscle, and liver (2022) (0)
- [Role of amylin in the physiologic and physiopathologic regulation of energy metabolism]. (1991) (0)
- Testing the activity of amylin. (1992) (0)
- Rat amylin-(8-37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats. (1997) (0)
- Posttranslational modifications within the collagenous domain of adiponectin are required for the formation of its high‐molecular‐weight oligomeric complex (2006) (0)
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