Gary E. Shull
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Biology
Gary E. Shull's Degrees
- PhD Physiology University of California, San Diego
- Bachelors Biology University of California, San Diego
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(Suggest an Edit or Addition)Gary E. Shull's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Renal and intestinal absorptive defects in mice lacking the NHE3 Na +/H+ exchanger (1998) (846)
- Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps. (1992) (655)
- Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA (1985) (619)
- Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain. (1986) (617)
- Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. (1992) (598)
- Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf* (1999) (396)
- cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump. (1989) (364)
- Molecular cloning of the rat stomach (H+ + K+)-ATPase. (1986) (360)
- Targeted Ablation of Plasma Membrane Ca2+-ATPase (PMCA) 1 and 4 Indicates a Major Housekeeping Function for PMCA1 and a Critical Role in Hyperactivated Sperm Motility and Male Fertility for PMCA4* (2004) (316)
- Balance and Hearing Deficits in Mice with a Null Mutation in the Gene Encoding Plasma Membrane Ca2+-ATPase Isoform 2* (1998) (306)
- Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases. (1988) (297)
- The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. (2010) (285)
- Phenotype Resembling Gitelman’s Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule* (1998) (282)
- Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3 − Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger* (1999) (278)
- Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 (SERCA2) Gene* (1999) (276)
- Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. (1998) (258)
- Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger. (1993) (222)
- Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. (1999) (215)
- Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome. (2004) (210)
- Cloning and Functional Expression of a Human Kidney Na+:HCO3 −Cotransporter* (1997) (205)
- Amino-acid sequence of the β-subunit of the (Na+ + K+)ATPase deduced from a cDNA (1986) (200)
- Molecular cloning of a third isoform of the calmodulin-sensitive plasma membrane Ca2+-transporting ATPase that is expressed predominantly in brain and skeletal muscle. (1989) (191)
- Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice. (2000) (185)
- Isolation and characterization of a cDNA encoding the putative distal colon H+,K(+)-ATPase. Similarity of deduced amino acid sequence to gastric H+,K(+)-ATPase and Na+,K(+)-ATPase and mRNA expression in distal colon, kidney, and uterus. (1992) (182)
- cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger. (1990) (176)
- Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. (1999) (175)
- Absence of Small Conductance K+ Channel (SK) Activity in Apical Membranes of Thick Ascending Limb and Cortical Collecting Duct in ROMK (Bartter's) Knockout Mice* (2002) (171)
- Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release. (2002) (168)
- Stomachs of Mice Lacking the Gastric H,K-ATPase α-Subunit Have Achlorhydria, Abnormal Parietal Cells, and Ciliated Metaplasia* (2000) (167)
- Impaired Renal NaCl Absorption in Mice Lacking the ROMK Potassium Channel, a Model for Type II Bartter's Syndrome* (2002) (167)
- Micropuncture analysis of single-nephron function in NHE3-deficient mice. (1999) (162)
- Alternative splicing of exons encoding the calmodulin-binding domains and C termini of plasma membrane Ca(2+)-ATPase isoforms 1, 2, 3, and 4. (1993) (156)
- Intestinal NaCl transport in NHE2 and NHE3 knockout mice. (2002) (152)
- Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice. (1998) (152)
- Phenotypes of SERCA and PMCA knockout mice. (2004) (152)
- Molecular Cloning, Genomic Organization, and Functional Expression of Na+/H+ Exchanger Isoform 5 (NHE5) from Human Brain* (1999) (151)
- Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells. (1993) (147)
- Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. (2007) (144)
- Na+-Dependent Chloride Transporter (NKCC1)-Null Mice Exhibit Less Gray and White Matter Damage after Focal Cerebral Ischemia (2005) (141)
- Disruption of a Single Copy of the SERCA2 Gene Results in Altered Ca2+ Homeostasis and Cardiomyocyte Function* (2000) (140)
- Null Mutation in the Gene Encoding Plasma Membrane Ca2+-ATPase Isoform 2 Impairs Calcium Transport into Milk* (2004) (131)
- NBCe1 Mediates the Acute Stimulation of Astrocytic Glycolysis by Extracellular K+ (2011) (127)
- Primary structure of the rat kidney band 3 anion exchange protein deduced from a cDNA. (1989) (126)
- The Rat Distal Colon P-ATPase Subunit Encodes a Ouabain-sensitive H,K-ATPase (*) (1996) (124)
- A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness (2007) (121)
- Na-K-Cl Cotransporter-Mediated Intracellular Na+ Accumulation Affects Ca2+ Signaling in Astrocytes in an In Vitro Ischemic Model (2004) (120)
- Defective Endothelium-dependent Relaxation of Vascular Smooth Muscle and Endothelial Cell Ca2+ Signaling in Mice Lacking Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 3* (1997) (119)
- Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule. (2000) (116)
- Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice. (2004) (116)
- Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits. (2013) (115)
- Molecular cloning and tissue distribution of alternatively spliced mRNAs encoding possible mammalian homologues of the yeast secretory pathway calcium pump. (1992) (113)
- Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter. (2002) (112)
- Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics (2001) (112)
- Characterization of the P5 subfamily of P-type transport ATPases in mice. (2004) (111)
- Decreased Neuronal Death in Na+/H+ Exchanger Isoform 1-Null Mice after In Vitro and In Vivo Ischemia (2005) (110)
- Loss of the Atp2c1 Secretory Pathway Ca2+-ATPase (SPCA1) in Mice Causes Golgi Stress, Apoptosis, and Midgestational Death in Homozygous Embryos and Squamous Cell Tumors in Adult Heterozygotes* (2007) (109)
- Loss of Hyperpolarization-activated Cl− Current in Salivary Acinar Cells from Clcn2 Knockout Mice* (2002) (108)
- Squamous Cell Tumors in Mice Heterozygous for a Null Allele of Atp2a2, Encoding the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 Ca2+Pump* (2001) (105)
- Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure (2012) (104)
- Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity. (2004) (103)
- PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum. (2007) (102)
- cDNA cloning of the beta-subunit of the rat gastric H,K-ATPase. (1990) (101)
- Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury (2005) (100)
- SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells. (2002) (100)
- Three N-terminal Variants of the AE2 Cl/HCO Exchanger Are Encoded by mRNAs Transcribed from Alternative Promoters (*) (1996) (100)
- CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity (2004) (100)
- Multiple mRNAs from rat kidney and brain encode a single Na+,K+-ATPase beta subunit protein. (1987) (99)
- Mice With a Null Mutation in the NHE1 Na+-H+ Exchanger Are Resistant to Cardiac Ischemia-Reperfusion Injury (2003) (98)
- Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide (1987) (97)
- Mice with a Targeted Disruption of the AE2 Exchanger Are Achlorhydric (2004) (97)
- SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+. (2005) (96)
- The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption. (2012) (94)
- Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. (2001) (93)
- Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach (2008) (92)
- An alternate pathway of cAMP-stimulated Cl secretion across the NKCC1-null murine duodenum. (2002) (91)
- Gene knockout studies of Ca2+-transporting ATPases. (2000) (88)
- Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth. (2013) (88)
- The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation. (2004) (87)
- Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric. (2004) (86)
- Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice (2002) (83)
- Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. (2009) (81)
- Impaired Gastric Acid Secretion in Mice with a Targeted Disruption of the NHE4 Na+/H+ Exchanger* (2005) (81)
- Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice. (2001) (81)
- CFTR induces the expression of DRA along with Cl(-)/HCO(3)(-) exchange activity in tracheal epithelial cells. (2000) (80)
- Plasticity and adaptation of Ca2+ signaling and Ca2+‐dependent exocytosis in SERCA2+/− mice (2001) (74)
- Haploinsufficiency of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility. (2005) (74)
- Defective Fluid Secretion and NaCl Absorption in the Parotid Glands of Na+/H+ Exchanger-deficient Mice* (2001) (73)
- Hypotension in NKCC1 null mice: role of the kidneys. (2006) (73)
- Membrane‐limited expression and regulation of Na+‐H+ exchanger isoforms by P2 receptors in the rat submandibular gland duct (1998) (72)
- Kinetic and Pharmacological Properties of Human Brain Na+/H+ Exchanger Isoform 5 Stably Expressed in Chinese Hamster Ovary Cells* (2000) (69)
- Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine. (2005) (69)
- Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. (2000) (69)
- Deficiency of ATP2C1, a Golgi Ion Pump, Induces Secretory Pathway Defects in Endoplasmic Reticulum (ER)-associated Degradation and Sensitivity to ER Stress* (2005) (68)
- Identification of an apical Cl-/HCO3- exchanger in gastric surface mucous and duodenal villus cells. (2003) (66)
- Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice. (2004) (65)
- Gastric achlorhydria in H/K‐ATPase‐deficient (Atp4a(–/–)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors (2005) (65)
- Primary structure of rat plasma membrane Ca(2+)-ATPase isoform 4 and analysis of alternative splicing patterns at splice site A. (1995) (64)
- Physiological Functions of Plasma Membrane and Intracellular Ca2+ Pumps Revealed by Analysis of Null Mutants (2003) (64)
- Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect. (2003) (63)
- NHE4 is critical for the renal handling of ammonia in rodents. (2010) (63)
- Targeted Disruption of the Nhe1 Gene Prevents Muscarinic Agonist-induced Up-regulation of Na+/H+ Exchange in Mouse Parotid Acinar Cells* (1999) (62)
- Translational control of ferritin synthesis by iron in embryonic reticulocytes of the bullfrog. (1982) (62)
- NHE3 Na+/H+ exchanger supports proximal tubular protein reabsorption in vivo. (2004) (61)
- Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes. (2001) (61)
- Role of Na+-K+-Cl- cotransport and Na+/Ca2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia. (2007) (61)
- Ischemic-reperfusion injury in the kidney: overexpression of colonic H+-K+-ATPase and suppression of NHE-3. (1997) (61)
- Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke (2018) (60)
- A possible molecular basis of natriuresis during ischemic-reperfusion injury in the kidney. (1998) (59)
- The importance of the 3'-untranslated region in the translational control of ferritin mRNA. (1988) (59)
- A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland (2015) (58)
- Molecular Cloning of Two Isoforms of the Plasma Membrane Ca 2 +-transporting ATPase from Rat Brain (58)
- Colocalization of the apical Cl-/HCO3- exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells. (2002) (58)
- SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity (2016) (55)
- Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice. (2009) (53)
- NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice. (2006) (53)
- Transepithelial HCO3- absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice. (2004) (52)
- Differential expression and regulation of AE2 anion exchanger subtypes in rabbit parietal and mucous cells (2001) (52)
- Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis. (2002) (52)
- Cloning, renal distribution, and regulation of the rat Na+-[Formula: see text]cotransporter. (1998) (51)
- NHE2‐mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice (2004) (50)
- The Electrogenic Sodium Bicarbonate Cotransporter NBCe1 Is a High-Affinity Bicarbonate Carrier in Cortical Astrocytes (2014) (49)
- Interleukin 18 function requires both interleukin 18 receptor and Na-Cl co-transporter (2015) (48)
- ERK1/2-p90RSK-mediated Phosphorylation of Na+/H+ Exchanger Isoform 1 (2007) (48)
- Inactivation of the Na‐Cl Co‐Transporter (NCC) Gene Is Associated With High BMD Through Both Renal and Bone Mechanisms: Analysis of Patients With Gitelman Syndrome and Ncc Null Mice (2004) (48)
- Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice. (2006) (47)
- Characterization of cDNA clones encoding two putative isoforms of the α1 subunit of the dihydropyridine‐sensitive voltage‐dependent calcium channel isolated from rat brain and rat aorta (1989) (47)
- cDNA cloning of the β-subunit of the rat gastric H,K-ATPase (1990) (47)
- Conservation of an AE3 Cl-/HCO3- exchanger cardiac-specific exon and promoter region and AE3 mRNA expression patterns in murine and human hearts. (1995) (47)
- Structure of the rat plasma membrane Ca(2+)-ATPase isoform 3 gene and characterization of alternative splicing and transcription products. Skeletal muscle-specific splicing results in a plasma membrane Ca(2+)-ATPase with a novel calmodulin-binding domain. (1992) (47)
- Blindness Caused by Deficiency in AE3 Chloride/Bicarbonate Exchanger (2007) (45)
- In Vivo Evidence for Interferon-γ-mediated Homeostatic Mechanisms in Small Intestine of the NHE3 Na+/H+ Exchanger Knockout Model of Congenital Diarrhea* (2002) (44)
- AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon. (2010) (44)
- The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice (2005) (44)
- Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule. (2001) (43)
- Conservation of Hearing by Simultaneous Mutation of Na,K-ATPase and NKCC1 (2007) (43)
- Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle. (1999) (43)
- Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2. (2005) (41)
- Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract. (2000) (40)
- Muscarinic receptor‐induced acidification in sublingual mucous acinar cells: loss of pH recovery in Na+−H+ exchanger‐1 deficient mice (2000) (39)
- Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKalpha isoforms. (2008) (38)
- [Formula: see text] reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. (1999) (38)
- Distinct Phenotypes among Plasma Membrane Ca2+‐ATPase Knockout Mice (2007) (38)
- Amino-acid sequence of the beta-subunit of the (Na+ + K+)ATPase deduced from a cDNA. (1986) (38)
- A Concerted Role of Na+—K+—Cl− Cotransporter and Na+/Ca2+ Exchanger in Ischemic Damage (2008) (36)
- Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice. (2007) (34)
- Rat kidney band 3 Cl-/HCO3- exchanger mRNA is transcribed from an alternative promoter. (1993) (33)
- Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2. (2008) (33)
- Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel. (2009) (33)
- Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction. (2011) (33)
- Loss of acidification of anterior prostate fluids in Atp12a-null mutant mice indicates that nongastric H-K-ATPase functions as proton pump in vivo. (2006) (32)
- Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post‐stroke function recovery (2018) (32)
- Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress. (2013) (32)
- Colonic H(+)-K(+)-ATPase in K(+) conservation and electrogenic Na(+) absorption during Na(+) restriction. (2001) (32)
- Cloning and sequence analysis of rat cystic fibrosis transmembrane conductance regulator. (1992) (32)
- Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension. (2015) (31)
- Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter. (1998) (31)
- Sarco(endo)plasmic Reticulum Ca2+ ATPase Isoforms and Their Role in Muscle Physiology and Pathology (1998) (30)
- Structure of the human gastric H,K-ATPase gene and comparison of the 5'-flanking sequences of the human and rat genes. (1990) (30)
- Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases. (2008) (30)
- Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. (2011) (29)
- HCO-3 reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. (1999) (29)
- SLC4A2-mediated Cl−/HCO3− exchange activity is essential for calpain-dependent regulation of the actin cytoskeleton in osteoclasts (2013) (29)
- Regulation of ferritin mRNA: a possible gene-sparing phenomenon. Induction of ferritin synthesis by iron in liver as well as red cells combines high translational efficiency with increased utilization of preformed ferritin mRNA. (1983) (29)
- Increased Tolerance to Ischemic Neuronal Damage by Knockdown of Na+–Ca2+ Exchanger Isoform 1 (2007) (29)
- Ae4 (Slc4a9) is an electroneutral monovalent cation-dependent Cl−/HCO3− exchanger (2016) (28)
- Variant form of diffuse corporal gastritis in NHE2 knockout mice. (2000) (28)
- The electroneutral Na+:HCO3− cotransporter NBCn1 is a major pHi regulator in murine duodenum (2012) (27)
- Electroneutral sodium absorption and electrogenic anion secretion across murine small intestine are regulated in parallel. (2004) (27)
- Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts. (2009) (27)
- Aberrant retinal projections in congenitally deaf mice: how are phenotypic characteristics specified in development and evolution? (2005) (26)
- In Vivo Epithelial Wound Repair Requires Mobilization of Endogenous Intracellular and Extracellular Calcium* (2013) (26)
- Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. (1999) (25)
- Acidic Conditions in the NHE2-/- Mouse Intestine Result in an Altered Mucosa-Associated Bacterial Population with Changes in Mucus Oligosaccharides (2013) (25)
- Molecular cloning and physical and genetic mapping of the human anion exchanger isoform 3 (SLC2C) gene to chromosome 2q36. (1994) (25)
- Critical role of bicarbonate and bicarbonate transporters in cardiac function. (2014) (25)
- The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+-ATPase (2002) (24)
- Novel Schering and ouabain-insensitive potassium-dependent proton secretion in the mouse cortical collecting duct. (2002) (24)
- Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines (2015) (23)
- Ae4 (Slc4a9) Anion Exchanger Drives Cl− Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells* (2015) (23)
- Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene. (1996) (22)
- SLC 26 A 9 is expressed in gastric surface epithelial cells , mediates Cl / HCO 3 exchange , and is inhibited by NH 4 (2005) (22)
- The effect of manganese exposure in Atp13a2‐deficient mice (2017) (21)
- Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse. (2016) (20)
- Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase. (2006) (20)
- Rat gastric H,K-ATPase beta-subunit gene: intron/exon organization, identification of multiple transcription initiation sites, and analysis of the 5'-flanking region. (1991) (20)
- Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+‐H+ exchanger NHE3 (2003) (19)
- Regulation of gene expression by hypoxia: a molecular approach. (1997) (19)
- SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure (2015) (19)
- Cotransporter-Mediated Intracellular Na Accumulation Affects Ca 2 Signaling in Astrocytes in an In Vitro Ischemic Model (2004) (19)
- Cloning , renal distribution , and regulation of the rat Na 1-HCO 3 2 cotransporter (1998) (18)
- Cloning , renal distribution , and regulation of the rat Na 1-HCO 3 2 cotransporter (1998) (18)
- Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. (1999) (17)
- Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice (2016) (17)
- Protein aggregation in neurons following OGD: a role for Na+ and Ca2+ ionic dysregulation (2010) (16)
- NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease. (2014) (16)
- Endoplasmic reticulum Ca2+ signaling and mitochondrial Cyt c release in astrocytes following oxygen and glucose deprivation (2010) (16)
- The apical anion exchanger Slc26a6 promotes oxalate secretion by murine submandibular gland acinar cells (2018) (16)
- Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion (2015) (16)
- Mouse chromosomal location of four Na/H exchanger isoform genes. (1996) (15)
- CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor. (2010) (14)
- Pharmacological profiles of the murine gastric and colonic H,K-ATPases. (2010) (12)
- Mice with a Targeted Disruption of the AE2 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{Cl}^{-}{/}\mathrm{HCO}_{3}^{-}\) \end{document} Exchanger Are Achlorhydric* (2004) (11)
- The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice. (2002) (10)
- Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. (2014) (10)
- NBCe1 Na+-HCO3- cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury in vivo (2018) (9)
- Loss of the AE3 Cl−/HCO−3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart (2013) (9)
- NHE 1 in cerebral ischemic damage 1 ERK 1 / 2P 90 RSK-MEDIATED PHOSPHORYLATION OF NA + / H + EXCHANGER ISOFORM 1 : A ROLE IN ISCHEMIC NEURONAL DEATH (2007) (8)
- Loss of the NHE2 Na+/H+ Exchanger in Mice Results in Dilation of Folliculo-Stellate Cell Canaliculi (2011) (8)
- Colonic Anion Secretory Defects and Metabolic Acidosis in Mice Lacking the NBC1 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{Na}^{+}{/}\mathrm{HCO}_{3}^{-}\) \end{document} Cotra (2007) (8)
- Inhibition of Na+/H+ exchanger isoform 1 attenuates mitochondrial cytochrome C release in cortical neurons following in vitro ischemia. (2006) (7)
- NHE 2 is the main apical NHE in mouse colonic crypts but an alternative Na-dependent acid extrusion mechanism is upregulated in NHE 2-null mice (2006) (7)
- Differential inhibition of protein synthesis: a possible biochemical mechanism of thalidomide teratogenesis. (1984) (7)
- Analysis of the 5' end of the rat plasma membrane Ca(2+)-ATPase isoform 3 gene and identification of extensive trinucleotide repeat sequences in the 5' untranslated region. (1995) (7)
- The Na / H exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE 3 upregulation (2004) (7)
- The HVCN1 voltage‐gated proton channel contributes to pH regulation in canine ventricular myocytes (2022) (6)
- Volume Density, Distribution, and Ultrastructure of Secretory and Basolateral Membranes and Mitochondria Predict Parietal Cell Secretory (Dys)function (2010) (6)
- Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans (2016) (5)
- Micropuncture analysis of single-nephron function in NHE3-deficient mice. (1999) (5)
- Transepithelial HCO 3 absorption is defective in renal thick ascending limbs from Na / H exchanger NHE 1 null mutant mice (5)
- Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic β cell function in type 2 diabetes. (2021) (4)
- NHE 2-mediated bicarbonate reabsorption in the distal tubule of NHE 3 null mice (2013) (3)
- The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice (The Journal of Clinical Investigation (2011), 121, 4, (1668) DOI: 10.1172/JCI57722) (2011) (3)
- Isolation and characterization of a cDNA for the catalytic subunit of the (Na+ + K+)-ATPase. (1987) (3)
- Overview: amino acid sequences of the alpha and beta subunits of the Na,K-ATPase. (1988) (3)
- RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3− Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart (2017) (3)
- Ablation of the SERCA 3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle (1999) (2)
- Uroguanylin but not guanylin knockout mice have diminished sodium excretion in response to an enteral salt load (2003) (2)
- Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine. (2016) (2)
- Intestinal brush‐border Na+/H+ exchangers are required for iron homeostasis in the mouse (2011) (2)
- Distinct roles of PMCA1 and 4 in Ca2+-homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice (2007) (2)
- special communication Colocalization of the apical Cl/HCO 3 exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells (2002) (2)
- 788 Effect of Genetic Ablation of the Acid/Base Transporters PNBC1, NHE1, NHE2, and Slc26a7, On Gastric Epithelial Functions (2009) (1)
- Sa1946 Role of the Electrogenic Na+HCO3- Cotransporter NBCe1 in PHI Regulation and Anion Secretion in Murine Intestine (2013) (1)
- 1 1 2 AE 2 Cl-/ HCO 3-Exchanger is Required for Normal cAMP-stimulated 3 Anion Secretion in Murine Proximal Colon (2009) (1)
- Role of plasma membrane Ca2+‐ATPase (PMCA) in bladder Ca2+ homeostasis and contractility: Data from PMCA1 and PMCA4 gene‐targeted mice (2006) (1)
- Session 7: Intestinal iron transport (2011) (0)
- Unraveling ammonia transport: Role of NHE2/3 and cH/K‐ATPase (2012) (0)
- Contribution of NHE2 and NHE3 to Na absorption in the murine jejunum (2000) (0)
- Phosphoproteomic Analysis of Signaling Responses to Angiotensin II in Proximal Tubules of NHE3‐deficient Mice (2013) (0)
- The AE2 subtypes are differentially expressed and regulated in rabbit parietal and mucous cells (2000) (0)
- Selective Knockout of Astrocytic Na+/H+ Exchanger Isoform 1 is Neuroprotective in Ischemic Stroke Injury (2016) (0)
- Mouse SERCA2b is Critical in Compensatory Response to High Fat Diet by Maintaining Pancreatic β Cell Proliferation (2016) (0)
- Sa1122 – The Electrogenic Na+/HCO3- CO-Transporter (NBCE1/SLC4A4) is Necessary FOR Normal Electrical Slow Wave Activity in the Mouse Small Intestine (2019) (0)
- Dual role of the Na+/H+ exchanger isoform 3 for PEPT1‐mediated H+/dipeptide cotransport in native murine intestine (2009) (0)
- Abstract 42: A Novel Role of Proximal Tubular Na+/H+ Exchanger 3 (NHE3) in Angiotensin II-Induced Hypertension in Nhe3-/- Mice with Transgenic Rescue of NHE3 in Intestines (2013) (0)
- Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle. (1999) (0)
- Role of Na+‐HCO3‐ cotransporter NBCe1 (Slc4a4) in colonic pHi regulation and anion transport (893.38) (2014) (0)
- RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3− Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart (2017) (0)
- intestinal obstructions in cystic fibrosis mice Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of (2009) (0)
- Evidence from PMCA gene‐ablated mice for distinct roles of PMCA 1 & 4 isoforms: PMCA4 linked with ACh‐receptor function in Ca2+‐homeostasis of bladder smooth muscle (2007) (0)
- Nhe2 is predominantly crypt-localized in murine proximal colon and its lack causes an anion secretory defect in NHE2-/- mice (2003) (0)
- NHE 2 is the main apical Na + / H + exchanger in mouse colonic crypts but an alternative Na +-dependent acid extrusion mechanism is upregulated in NHE 2-null mice (2006) (0)
- 209 Deletion of the Chloride Transporter Slc26a9 Causes Loss of Tubulovesicles in Gastric Parietal Cells and Impairs Acid Secretion (2008) (0)
- Role of the AE3 Chloride/Bicarbonate Exchanger in the Development of Cardiac Hypertrophy (2008) (0)
- Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice (2016) (0)
- exchanger isoform 1 null mice + /H + astrocytes from Na Increased tolerance to oxygen and glucose deprivation in (2016) (0)
- The Na + /H + exchanger isoform 3 is the key proton recycling mechanism to drive PepT1-mediated dipeptide transport in native murine intestine (2008) (0)
- Role of plasma membrane Ca2+-ATPase (PMCA) in contraction-relaxation processes of the bladder using PMCA gene manipulation (2006) (0)
- Intestinal brush-border Na (cid:2) /H (cid:2) exchanger-3 drives H (cid:2) -coupled iron absorption in the mouse (2016) (0)
- Ablation of intestinal brush‐border Na+/H+ exchanger NHE3 impairs iron absorption in the mouse (900.1) (2014) (0)
- Reduced Absorption Counters the Cystic Fibrosis Intestinal Phenotype and Increases Survival (2008) (0)
- Colonic H 1 -K 1 -ATPase in K 1 conservation and electrogenic Na 1 absorption during Na 1 restriction (2001) (0)
- Endothelium-dependent vascular relaxation is defective in mice lacking (SARCO)endoplasmic reticulum CA2+ ATPase isoform 3 (SERCA3) (1997) (0)
- Luminal [Na+] enhances Bacteroides thetaiotaomicron growth in vitro and in the NHE3−/− mouse terminal ileum (2013) (0)
- 889 NHE2−/− Mice Have Altered Intestinal Microbiota and Epithelia Oligosaccharide Patterns (2013) (0)
- Intestinal Microbiome in NHE2/3 Null Mouse Models (2011) (0)
- Gastric achlorhydria and abnormal incisor eruption in AE2 Cl-/HCO3- exchanger knockout mice (2003) (0)
- Abstract 11169: The HVCN1 Voltage-Gated Proton Channel Contributes to Ph Regulation in Canine Ventricular Myocytes (2021) (0)
- List of papers (2005) (0)
- Effects of PMCA1 knockout on ventricular cardiomyocyte calcium homeostasis. (2023) (0)
- PMCA, SERCA and Na, K ATPase Alpha Isoforms and Ca2+ Homeostasis in Smooth Muscle Evidence from Gene-Altered Mice (2003) (0)
- Translational control of ferritin synthesis: a study of repression using natural and synthetic mRNAs (1987) (0)
- The Na+/HCO3− Cotransporter (Nbce1, Slc4a4) is Enriched in Interstitial Cells of Cajal Responsible for Generating Electrical Slow Wave Activity in the Mouse Gastrointestinal Tract (2019) (0)
- The Ghost of the IEL: A Halloween Photoshop Exercise (2008) (0)
- CLIC5 is required for appropriate thermogenesis during fasting (2009) (0)
- CAMP stimulated anion secretion across NKCC1 knockout intestine (2000) (0)
- Community Dynamics in the Mouse Gut Microbiota: Role of NHE3 (2012) (0)
- NHE3 and Clostridium difficile infection (897.5) (2014) (0)
- T1871 Differential Roles of Slc26a6 and NHE3 for Enterocyte PHI Regulation and Substrate Transport Rates Via SGLT1 and Pept1 (2008) (0)
- Mice With a Null Mutation in the NHE1 Na (cid:1) -H (cid:1) Exchanger Are Resistant to Cardiac Ischemia-Reperfusion Injury (2003) (0)
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