Gary J. Fisher
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(Suggest an Edit or Addition)Gary J. Fisher's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mechanisms of photoaging and chronological skin aging. (2002) (1445)
- Pathophysiology of premature skin aging induced by ultraviolet light. (1997) (1317)
- Molecular basis of sun-induced premature skin ageing and retinoid antagonism (1996) (1308)
- UV-light-induced signal cascades and skin aging (2002) (820)
- Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. (2006) (606)
- Matrix-degrading metalloproteinases in photoaging. (2009) (537)
- Overexpression of transforming growth factor alpha in psoriatic epidermis. (1989) (532)
- In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. (2007) (483)
- Molecular mechanisms of retinoid actions in skin (1996) (413)
- Looking older: fibroblast collapse and therapeutic implications. (2008) (409)
- Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. (1998) (370)
- Reduced type I and type III procollagens in photodamaged adult human skin. (1995) (362)
- Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. (2009) (352)
- Natural and sun-induced aging of human skin. (2015) (309)
- Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. (2004) (306)
- c-Jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid. (2000) (292)
- Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo. (1998) (290)
- Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. (1995) (279)
- Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review (2015) (239)
- Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. (2003) (225)
- Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo. (2005) (224)
- Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. (2000) (221)
- Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. (2003) (221)
- Expression of growth hormone receptor, insulin-like growth factor 1 (IGF-1) and IGF-1 receptor mRNA and proteins in human skin. (1992) (208)
- Retinoic acid receptor gene expression in human skin. (1991) (203)
- Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin. (1991) (182)
- Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin. (1994) (179)
- Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. (2010) (174)
- Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells and keratinocytes in aged human skin in vivo (2012) (171)
- Improvement of naturally aged skin with vitamin A (retinol). (2007) (168)
- Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. (2004) (167)
- Extracellular matrix regulation of fibroblast function: redefining our perspective on skin aging (2018) (166)
- Matrix Metalloproteinase‐1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV‐irradiated Human Skin ¶ (2003) (163)
- Connective tissue remodeling induced by carbon dioxide laser resurfacing of photodamaged human skin. (2004) (158)
- Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo. (2002) (157)
- Matrix Metalloproteinase-1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV-irradiated Human Skin¶ (2003) (155)
- Ultraviolet Irradiation Blocks Cellular Responses to Transforming Growth Factor-β by Down-regulating Its Type-II Receptor and Inducing Smad7* (2001) (154)
- Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo. (2000) (153)
- Ultraviolet irradiation increases matrix metalloproteinase-8 protein in human skin in vivo. (2001) (153)
- Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial. (2004) (149)
- Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis. (2002) (148)
- Ultraviolet modulation of human macrophage metalloelastase in human skin in vivo. (2002) (146)
- Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo. (2001) (140)
- Oxidative Inhibition of Receptor-type Protein-tyrosine Phosphatase κ by Ultraviolet Irradiation Activates Epidermal Growth Factor Receptor in Human Keratinocytes* (2006) (135)
- Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway. (2011) (132)
- Auto-regulation of Retinoic Acid Biosynthesis through Regulation of Retinol Esterification in Human Keratinocytes* (1996) (130)
- Elevated Matrix Metalloproteinases and Collagen Fragmentation in Photodamaged Human Skin: Impact of Altered Extracellular Matrix Microenvironment on Dermal Fibroblast Function (2012) (127)
- Interleukin-1 receptor antagonist in normal and psoriatic epidermis. (1992) (126)
- IL-1 activity is reduced in psoriatic skin: Decreased IL-1α and increased nonfunctional IL-1β (1990) (124)
- Eccrine sweat glands are major contributors to reepithelialization of human wounds. (2013) (124)
- Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels. (1992) (120)
- Isolation and culture of skin fibroblasts. (2005) (119)
- Epidermal Growth Factor Receptor-dependent, NF-κB-independent Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Inhibits Ultraviolet Irradiation-induced Caspases-3, -8, and -9 in Human Keratinocytes* (2003) (119)
- Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All‐Trans Retinoic Acid (1999) (119)
- Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum free versus serum containing media. (1988) (116)
- Dermal matrix remodeling after nonablative laser therapy. (2005) (116)
- Decreased protein kinase C activity in psoriatic versus normal epidermis. (1987) (114)
- The pathophysiology of photoaging of the skin. (2005) (113)
- Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo. (2006) (108)
- Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor‐α production in keratinocytes cultured from psoriatic lesions (1989) (107)
- Biological activity of all-trans retinol requires metabolic conversion to all-trans retinoic acid and is mediated through activation of nuclear retinoid receptors in human keratinocytes. (1994) (107)
- Molecular effects of photodynamic therapy for photoaging. (2008) (103)
- Ultraviolet (UV) light irradiation induced signal transduction in skin photoaging (2005) (102)
- Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. (2006) (102)
- Receptor-type Protein-tyrosine Phosphatase-κ Regulates Epidermal Growth Factor Receptor Function* (2005) (99)
- Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin. (1988) (98)
- Cyclosporine in dermatology. (1989) (95)
- Topical tretinoin (retinoic acid) improves early stretch marks. (1996) (94)
- UM4D4+ (CDw60) T cells are compartmentalized into psoriatic skin and release lymphokines that induce a keratinocyte phenotype expressed in psoriatic lesions. (1990) (92)
- Activation of human platelets by ADP causes a rapid rise in cytosolic free calcium without hydrolysis of phosphatidylinositol-4,5-bisphosphate. (1985) (91)
- Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation (2013) (91)
- 1,25-Dihydroxyvitamin D3 increases nuclear vitamin D3 receptors by blocking ubiquitin/proteasome-mediated degradation in human skin. (1999) (90)
- T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinocyte proliferation. (1993) (88)
- Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: reduced expression of protein kinase C-beta II in psoriasis. (1993) (88)
- Ultraviolet Irradiation Induces Smad7 via Induction of Transcription Factor AP-1 in Human Skin Fibroblasts* (2005) (83)
- Type I collagen D-spacing in fibril bundles of dermis, tendon, and bone: bridging between nano- and micro-level tissue hierarchy. (2012) (82)
- Ubiquitin/Proteasome Pathway Regulates Levels of Retinoic Acid Receptor γ and Retinoid X Receptor α in Human Keratinocytes (2000) (82)
- Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo. (2008) (81)
- The role of immune system in the pathogenesis of psoriasis. (1990) (78)
- Age-dependent alterations of decorin glycosaminoglycans in human skin (2013) (75)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin (2016) (75)
- ATP-dependent calcium transport across basal plasma membranes of human placental trophoblast. (1987) (74)
- YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts (2018) (74)
- Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin. (2007) (74)
- Epidermal growth factor receptor is a critical mediator of ultraviolet B irradiation-induced signal transduction in immortalized human keratinocyte HaCaT cells. (2006) (74)
- Regulation of membrane-associated and cytosolic phospholipase C activities in human platelets by guanosine triphosphate. (1986) (74)
- Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging (2015) (74)
- Connective tissue growth factor: expression in human skin in vivo and inhibition by ultraviolet irradiation. (2002) (72)
- Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin (2009) (71)
- Microdermabrasion: a molecular analysis following a single treatment. (2005) (71)
- Isolation, purification, and properties of a unique form of cytochrome P-450 in microsomes of isosafrole-treated rats. (1981) (70)
- UV-A1 phototherapy improves nephrogenic fibrosing dermopathy. (2004) (69)
- Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. (2010) (68)
- Ultraviolet irradiation‐induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes (2009) (66)
- Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. (2005) (65)
- Reconstitution of thromboxane A2 receptor-stimulated phosphoinositide hydrolysis in isolated platelet membranes: involvement of phosphoinositide-specific phospholipase C-beta and GTP-binding protein Gq. (1993) (62)
- Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes. (1988) (62)
- Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment (1999) (60)
- Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment (1999) (60)
- Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors Mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy. (2001) (60)
- Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin (2016) (60)
- Receptor type protein tyrosine phosphatases (RPTPs) – roles in signal transduction and human disease (2012) (59)
- Differential modulation of transforming growth factor-beta 1 expression and mucin deposition by retinoic acid and sodium lauryl sulfate in human skin. (1992) (58)
- Elevated YAP and its downstream targets CCN1 and CCN2 in basal cell carcinoma: impact on keratinocyte proliferation and stromal cell activation. (2014) (58)
- Long-term treatment of photoaged human skin with topical retinoic acid improves epidermal cell atypia and thickens the collagen band in papillary dermis. (2005) (58)
- Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses. (2011) (58)
- T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal, epidermis. (1992) (56)
- Retinoic acid receptors regulate expression of retinoic acid 4-hydroxylase that specifically inactivates all-trans retinoic acid in human keratinocyte HaCaT cells. (1998) (56)
- Translocation and Downregulation of Protein Kinase C Isoenzymes-α and -ε by Phorbol Ester and Bryostatin-1 in Human Keratinocytes and Fibroblasts (1994) (55)
- Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts (2014) (54)
- GRO-alpha mRNA is selectively overexpressed in psoriatic epidermis and is reduced by cyclosporin A in vivo, but not in cultured keratinocytes. (1993) (54)
- Age-associated increase of skin fibroblast-derived prostaglandin E2 contributes to reduced collagen levels in elderly human skin (2015) (53)
- Amphiregulin and epidermal hyperplasia: amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice. (2005) (52)
- Erratum: Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment (Nature Medicine (1999) 5 (418-422)) (1999) (51)
- Clinical, Histologic, and Molecular Analysis of Differences Between Erythematotelangiectatic Rosacea and Telangiectatic Photoaging. (2015) (51)
- Interleukin-1 in human skin: dysregulation in psoriasis. (1990) (51)
- Effect of increased pigmentation on the antifibrotic response of human skin to UV-A1 phototherapy. (2008) (50)
- Increased phospholipase C-catalyzed hydrolysis of phosphatidylinositol-4,5-bisphosphate and 1,2-sn-diacylglycerol content in psoriatic involved compared to uninvolved and normal epidermis. (1990) (49)
- Expression of catalytically active matrix metalloproteinase‐1 in dermal fibroblasts induces collagen fragmentation and functional alterations that resemble aged human skin (2013) (47)
- Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis. (1989) (47)
- Epidermal growth factor‐induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts (1991) (47)
- CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts (2011) (45)
- Alterations in extracellular matrix composition during aging and photoaging of the skin (2020) (45)
- All-trans retinoic acid induces cellular retinol-binding protein in human skin in vivo. (1995) (44)
- The role of the immune system in the pathogenesis of psoriasis. (1990) (44)
- Cysteine‐rich protein 61 (CCN1) mediates replicative senescence‐associated aberrant collagen homeostasis in human skin fibroblasts (2012) (43)
- Retinoic acid metabolites exhibit biological activity in human keratinocytes, mouse melanoma cells and hairless mouse skin in vivo. (1993) (43)
- Ubiquitin/proteasome pathway regulates levels of retinoic acid receptor gamma and retinoid X receptor alpha in human keratinocytes. (2000) (42)
- Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo (2011) (41)
- Inhibition of fibrinogen receptor expression and serotonin release by leupeptin and antipain. (1985) (41)
- Long-Term Efficacy and Safety of Tretinoin Emollient Cream 0.05% in the Treatment of Photodamaged Facial Skin (2005) (40)
- Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin (2013) (40)
- Topical fluorouracil for actinic keratoses and photoaging: a clinical and molecular analysis. (2009) (39)
- Bradykinin induces phosphoinositide turnover, 1,2-diglyceride formation, and growth in cultured adult human keratinocytes. (1990) (39)
- UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytes. (2010) (39)
- IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta. (1990) (39)
- Dermal damage promoted by repeated low-level UV-A1 exposure despite tanning response in human skin. (2014) (39)
- Mitochondrial protein p26 BCL2 reduces growth factor requirements of NIH3T3 fibroblasts. (1991) (39)
- Molecular analysis of aggressive microdermabrasion in photoaged skin. (2009) (38)
- Oxidant Exposure Induces Cysteine-Rich Protein 61 (CCN1) via c-Jun/AP-1 to Reduce Collagen Expression in Human Dermal Fibroblasts (2014) (38)
- Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes. (1993) (37)
- Regulation of TGF‐α expression in human keratinocytes: PKC‐dependent and ‐independent pathways (1992) (37)
- Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory Signature (2012) (37)
- Regulation of Collagen Turnover in Human Skin Fibroblasts Exposed to a Gadolinium-Based Contrast Agent (2009) (37)
- Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts (2014) (37)
- Retinoids suppress cysteine‐rich protein 61 (CCN1), a negative regulator of collagen homeostasis, in skin equivalent cultures and aged human skin in vivo (2011) (35)
- Differential regulation of tyrosinase activity in skin of white and black individuals in vivo by topical retinoic acid. (1993) (35)
- Microdermabrasion with and without aluminum oxide crystal abrasion: a comparative molecular analysis of dermal remodeling. (2006) (35)
- Solar Ultraviolet Irradiation Induces Decorin Degradation in Human Skin Likely via Neutrophil Elastase (2013) (34)
- Intraepidermal erbium:YAG laser resurfacing: impact on the dermal matrix. (2011) (34)
- A mouse model of skin aging: fragmentation of dermal collagen fibrils and reduced fibroblast spreading due to expression of human matrix metalloproteinase-1. (2015) (33)
- Purification and characterization of calcium/phospholipid-dependent kinase from adult human epidermis. (1987) (32)
- Agonist-induced hydrolysis of phosphoinositides and formation of 1,2-diacylglycerol in adult human keratinocytes. (1989) (32)
- Genomic copy number analysis of a spectrum of blue nevi identifies recurrent aberrations of entire chromosomal arms in melanoma ex blue nevus (2016) (32)
- Effects of cyclosporine on immunologic mechanisms in psoriasis. (1990) (31)
- Isolation and characterization of one soluble and two membrane-associated forms of phosphoinositide-specific phospholipase C from human platelets. (1989) (30)
- Expression of CCN family of genes in human skin in vivo and alterations by solar-simulated ultraviolet irradiation (2009) (29)
- Receptor Type Protein Tyrosine Phosphatase-Kappa Mediates Cross-Talk between Transforming Growth Factor-Beta and Epidermal Growth Factor Receptor Signaling Pathways in Human Keratinocytes (2010) (29)
- Actin cytoskeleton assembly regulates collagen production via TGF‐β type II receptor in human skin fibroblasts (2018) (29)
- GTP and cytosol stimulate phosphoinositide hydrolysis in isolated platelet membranes. (1986) (29)
- Cysteine-rich Protein 61 (CCN1) Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression through αVβ3 Integrin in Human Skin Fibroblasts* (2013) (28)
- Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells. (2002) (28)
- Direct Quantitative Comparison of Molecular Responses in Photodamaged Human Skin to Fractionated and Fully Ablative Carbon Dioxide Laser Resurfacing (2012) (28)
- Growth factor and proto-oncogene expression in psoriasis. (1990) (27)
- Cloning and Characterization of the Human Protein Kinase C-η Promoter* (1999) (27)
- Increased membrane-associated transglutaminase activity in psoriasis. (1989) (27)
- Restoration of the basement membrane after wounding: a hallmark of young human skin altered with aging (2018) (26)
- Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses. (2015) (26)
- The effects of laser-mediated hair removal on immunohistochemical staining properties of hair follicles. (2006) (25)
- Phototherapy for scleroderma: biologic rationale, results, and promise (2002) (25)
- Atrophic and hypertrophic photoaging: Clinical, histologic, and molecular features of 2 distinct phenotypes of photoaged skin. (2019) (25)
- Receptor-type Protein Tyrosine Phosphatase β (RPTP-β) Directly Dephosphorylates and Regulates Hepatocyte Growth Factor Receptor (HGFR/Met) Function* (2011) (24)
- Direct cytopathic effects of cyclosporine A on rapidly proliferating cultured keratinocytes and dermal fibroblasts. (1988) (24)
- Effect of carbon dioxide laser resurfacing on epidermal p53 immunostaining in photodamaged skin. (2004) (24)
- Interactions of epidermal cells and T cells in inflammatory skin diseases. (1990) (23)
- GTPγS-stimulated hydrolysis of phosphatidyinositol-4,5-bisphosphate by soluble phospholipase C from human platelets requires soluble GTP-binding protein (1988) (23)
- Cancer resistance, high molecular weight hyaluronic acid, and longevity (2015) (23)
- Plasma membrane associated phospholipase C from human platelets: synergistic stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by thrombin and guanosine 5'-O-(3-thiotriphosphate). (1989) (23)
- Phosphoinositide-mediated signal transduction in normal and psoriatic epidermis. (1990) (22)
- Differential activation of human skin cells by platelet activating factor: stimulation of phosphoinositide turnover and arachidonic acid mobilization in keratinocytes but not in fibroblasts. (1989) (22)
- Retinoic acid and phorbol ester synergistically up-regulate IL-8 expression and specifically modulate protein kinase C-epsilon in human skin fibroblasts. (1992) (22)
- CD26 identifies a subpopulation of fibroblasts that produce the majority of collagen during wound healing in human skin. (2020) (22)
- Thrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cgamma1. (1997) (21)
- Cyclosporine inhibits ornithine decarboxylase gene expression and acute inflammation in response to phorbol ester treatment of hairless mouse skin. (1988) (21)
- PADMA 28: a multi-component herbal preparation with retinoid-like dermal activity but without epidermal effects. (2005) (21)
- Smad3-dependent regulation of type I collagen in human dermal fibroblasts: Impact on human skin connective tissue aging. (2016) (21)
- Tretinoin treatment before carbon-dioxide laser resurfacing: a clinical and biochemical analysis. (2004) (20)
- Ganglioside GT1b induces keratinocyte differentiation without activating protein kinase C. (1995) (20)
- Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin (2016) (20)
- Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes. (1993) (19)
- Regulation of TGF-alpha expression in human keratinocytes: PKC-dependent and -independent pathways. (1992) (19)
- CCN proteins as potential actionable targets in scleroderma (2018) (19)
- SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin (1997) (16)
- Cyclophilin content of normal and psoriatic epidermis. (1990) (16)
- Notch and TGF-β pathways cooperatively regulate receptor protein tyrosine phosphatase-κ (PTPRK) gene expression in human primary keratinocytes (2015) (16)
- Molecular mechanisms of photoaging in human skin in vivo and their prevention by all-trans retinoic acid. (1999) (16)
- Retinoic Acid Receptor-γ in Human Epidermis Preferentially Traps All-Trans Retinoic Acid as its Ligand Rather Than 9-cis Retinoic Acid (1998) (16)
- Receptor-type Protein tyrosine phosphatase β regulates met phosphorylation and function in head and neck squamous cell carcinoma. (2012) (15)
- Increased phosphatidylinositol kinase activity in psoriatic epidermis. (1989) (15)
- Interleukin-6 in psoriasis: expression and mitogenicity studies (2004) (15)
- Interleukin-1 in human skin: dysregulation in psoriasis. (1990) (14)
- Increased Activation of Ras in Psoriatic Lesions (1999) (14)
- Hypo‐collagenesis in photoaged skin predicts response to anti‐aging cosmeceuticals (2013) (14)
- Retinoid Therapy for Photoaging (2006) (13)
- Keratinocyte-specific retinoid regulation of human cellular retinoic acid binding protein-II (hCRABPII) gene promoter requires an evolutionarily conserved DR1 retinoic acid-responsive element. (1998) (13)
- Effect of membrane sterol content on the susceptibility of phospholipids to phospholipase A2. (1983) (13)
- Characterization and purification of human retinoic acid receptor-gamma 1 overexpressed in the baculovirus-insect cell system. (1992) (12)
- Kinetic investigation of rat liver microsomal electron transport from NADH to cytochrome P-450. (1982) (12)
- Langerhans cell sensitivity to in vitro versus in vivo loading with cyclosporine A. (1992) (12)
- Transforming Growth Factor‐β in Psoriasis: Pathogenesis and Therapy (1990) (12)
- Is ‘scarless wound healing’ applicable to glaucoma surgery? (2007) (11)
- Translocation and downregulation of protein kinase C isoenzymes-alpha and -epsilon by phorbol ester and bryostatin-1 in human keratinocytes and fibroblasts. (1994) (11)
- Gas chromatography-mass spectrometry analysis of effects of dietary fish oil on total fatty acid composition in mouse skin (2017) (11)
- Physical properties of the photodamaged human skin dermis: Rougher collagen surface and stiffer/harder mechanical properties (2018) (10)
- GTP-dependent hydrolysis of phosphatidylinositol-4,5-bisphosphate by soluble phospholipase C from adult human epidermis. (1987) (10)
- Elevated thymidine phosphorylase activity in psoriatic lesions accounts for the apparent presence of an epidermal "growth inhibitor," but is not in itself growth inhibitory. (1991) (10)
- Possible Contribution of Fibrocytes to Increased Type I Collagen Synthesis during the Early Stage of Dermal Wound Repair in Human Skin. (2018) (10)
- Skin Aging: Molecular Mechanisms and Tissue Consequences (2015) (9)
- Retinoic acid 4-hydroxylase inducibility and clinical response to isotretinoin in patients with acne. (2009) (9)
- Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis (2012) (9)
- Role of Met Axis in Head and Neck Cancer (2013) (8)
- Growth factor and proto-oncogene expression in psoriasis. (1990) (8)
- Erratum: Cellular, immunological and biochemical characterization of topical retinoic acid - Treated human skin (J. Investigative Dermatology, 96(5):699-707) (1991) (7)
- Ultraviolet irradiation represses TGF‐β type II receptor transcription through a 38‐bp sequence in the proximal promoter in human skin fibroblasts (2014) (7)
- Rejuvenation of Aged Human Skin by Injection of Cross-linked Hyaluronic Acid. (2020) (6)
- Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging. (2020) (5)
- Fibroblast Collapse and Therapeutic Implications (2017) (5)
- CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis? (2015) (5)
- Transforming growth factor-beta in psoriasis. Pathogenesis and therapy. (1990) (5)
- Mechanical Deformation of Cultured Cells with Hydrogels. (2017) (5)
- Targeted broadband ultraviolet B phototherapy improves disorders characterized by increased dermal matrix (2009) (5)
- Microsomal enzymes of cholesterol biosynthesis from lanosterol: A progress report (1982) (5)
- Topical retinoic acid induces tyrosinase activity in skin of white individuals in vivo (1992) (5)
- Retinoic acid receptor-gamma in human epidermis preferentially traps all-trans retinoic acid as its ligand rather than 9-cis retinoic acid. (1998) (4)
- Activation of ribosomal protein S6 kinase in psoriatic lesions and cultured human keratinocytes by epidermal growth factor receptor ligands. (1997) (4)
- Symposium-in-Print Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All-Trans Retinoic Acid (1999) (3)
- Cyclosporine for the treatment of psoriasis. (1988) (3)
- Aging and Photoaging of the Skin (2010) (3)
- Age-related elevation of HGF is driven by the reduction of fibroblast size in a YAP/TAZ/CCN2 axis-dependent manner. (2021) (3)
- A novel histone-stimulated protein kinase in normal and psoriatic epidermis. (1989) (2)
- Erratum: Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-α in normal human skin fibroblasts and keratinocytes (Biochemistry Journal (1993) 294 (535-544)) (1993) (2)
- Dietary Fish Oil Supplementation Enhances Expression of Genes Involved in Cornified Cell Envelope Formation in Rat Skin. (2017) (2)
- Montagna Symposium 2014—Skin Aging: Molecular Mechanisms and Tissue Consequences (2015) (2)
- Cyclooxygenases mediate early induction of interleukin-6 expression by solar ultraviolet irradiation in human skin. (2017) (2)
- Treatment of Acne Vulgaris With a Pulsed Dye Laser (2017) (1)
- Prostaglandins Contribute to the Effects of Solar Ultraviolet Irradiation on Type I Collagen and Matrix Metalloproteinase-1 Expression in Human Skin. (2016) (1)
- 142 The phenotype of dermal fibroblasts in young vs. aged human skin: Adaptation to dermal extracellular matrix deterioration and cell autonomous responses (2022) (1)
- Modulators of cutaneous inflammation and proliferation in psoriasis. (1989) (1)
- Deficiency of inhibitory TLR4 homolog RP105 exacerbates fibrosis (2022) (1)
- Topical Retinoids -Pharmacological, Cellular and Molecular Aspects1 (1991) (1)
- Identification of dihydrogambogic acid as a matrix metalloproteinase 1 inhibitor by high-throughput screening (2017) (1)
- Infrared irradiation differentially alters collagen metabolism in lightly and darkly pigmented human skin in vivo. (2016) (1)
- Reduced expression of Collagen 17A1 in naturally aged, photoaged, and UV-irradiated human skin in vivo: Potential links to epidermal aging (2022) (1)
- Pharmacology and molecular mechanisms of retinoid action in skin (2000) (1)
- Immunological and functional quantitation of nuclear retinoid X (RXR) and retinoic acid (RAR) receptor proteins in human epidermis in vivo: High levels of RXRS and RAR-γ, low levels of RAR-α, and absence of RAR-β (1993) (1)
- Proteasome inhibitors enhance vitamin D3 signaling via inhibiting degradation of vitamin D3 receptors in human keratinocytes (1998) (0)
- 443 Oxidative exposure elevates intracellular ROS through impairing ROS conversion/reduction (2019) (0)
- 085 CCN1-induced age-related dermal microenvironment promotes skin cancer development (2021) (0)
- Accumulation of Fragmented Collagen and Loss of Mechanical Tension During Aging (2010) (0)
- Calcium uptake by purified basal plasma membrane of the syncytiotrophoblast of the human placenta (1984) (0)
- PHOSPHATIDIC ACID A N D PHOSPHOLIPASE D BOTH STIMULATE PHOSPHOINOSITIDE TURNOVER IN CULTURED H U M A N KERATINOCYTES (2002) (0)
- Cyclosporine in dermatology (Reply) (1990) (0)
- GTPYS-STIMULATED HYDROLYSIS OF PHOSPHATIDYINOSITOL-4,5-BISPHOSPHATE BY SOLUBLE PHOSPHOLIPASE C FROM HUMAN PLATELETS REQUIRES SOLUBLE GTP-BINDING PROTEIN' (2003) (0)
- Psoriatic skin reveals the in vivo presence of an epidermal IL-1 inhibitor (2004) (0)
- Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes. (2023) (0)
- Retinoic acid protects against loss of types I and III procollagen caused by a single exposure to ultraviolet irradiation in human skin in vivo (1998) (0)
- YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts (2018) (0)
- 861 CCN2/Connective tissue growth factor regulates G1 to S phase cell cycle progression in human skin fibroblasts (2018) (0)
- 1,25-Dihydroxyvitamin D Nuclear Vitamin D 3 Receptors by Blocking Ubiquitin/Proteasome-Mediated Degradation in Human Skin (1999) (0)
- 1025 Onset, rate, and progression of human dermal extracellular matrix aging (2019) (0)
- 130 Hepatocyte growth factor pathway drives enhanced skin tumor formation in a humanized mouse model of accelerated dermal aging (2022) (0)
- Gene Expression of CCN Family Members in Young and Aged Human Skin In Vivo (2010) (0)
- 098 Age-related reduction of fibroblast size induces hepatocyte growth factor expression in a YAP/TAZ dependent manner (2021) (0)
- Erratum: Retinoic acid metabolites exhibit biological activity in human keratinocytes. Mouse melanoma cells and hairless mouse skin in vivo (Journal of Pharmacology and Experimental Therapeutics (1993) 266 (1636-1642)) (1994) (0)
- Ultraviolet irradiation blocks retinoid signaling in human skin through proteasome-mediated degradation of nuclear retinoid receptors (1998) (0)
- Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis (2012) (0)
- 701 Caloric restriction during aging alters expression of dermal extracellular matrix-related genes in mice (2021) (0)
- 520 High resolution transcriptome profiling identifies gene expression signatures unique to normal human keratinocytes, dermal fibroblasts, and endothelial cells (2017) (0)
- 296 Reduced sweat gland contribution and cell cohesion delay wound closure in elderly skin (2016) (0)
- Regulation of phosphoinositide hydrolysis and fibrinogen receptor expression by GTP regulatory protein(s) in isolated platelet membranes (1986) (0)
- 1107 Fibroblast culture model of dysregulated collagen homeostasis in aged human skin: Identification of natural compounds with restorative activity (2018) (0)
- Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts (2014) (0)
- Extracellular matrix regulation of fibroblast function: redefining our perspective on skin aging (2018) (0)
- Keratinocytes in Human α and Retinoid X Receptor γ Acid Receptor Ubiquitin / Proteasome Pathway Regulates Levels of Retinoic Updated (2000) (0)
- Iconography : Tretinoin treatment before carbon-dioxide laser resurfacing: A clinical and biochemical analysis (2011) (0)
- Collagen I and collagen III expression in young and old skin: Effects of topical retinol treatment of 80+ year old individuals (1998) (0)
- Phosphoinositide-mediated signal transduction in normal and psoriatic epidermis. (1990) (0)
- Ultraviolet irradiation rapidly activates cell surface receptors and three distinct map kinase modules in human skin in vivo (1998) (0)
- 267 Once weekly topical all-trans retinol restores type I collagen synthesis in photoaged forearm skin within 4 weeks: A protocol for evaluating anti-aging topical agents (2016) (0)
- 682 Gas chromatography-mass spectrometry analysis of effects of dietary fish oil on fatty acid composition in mouse skin (2017) (0)
- Keratinocyte-specific retinoid regulation of human cellular retinoic acid binding protein-II gene (hCRABPII) promoter requires sufficient levels of retinoid receptors and an evolutionarily conserved DR1 RA-responsive element (1998) (0)
- 914 Fibroblast heterogeneity in human skin: CD26 identifies a population of fibroblasts that upregulate collagen production in response to wounding (2017) (0)
- Protein kinase C in normal and psoriatic adult human epidermis. (1987) (0)
- Molecular Pathophysiology of Photoaging in Human Skin and the Effect of All-Trans Retinoic Acid (1999) (0)
- GTP gamma S-stimulated hydrolysis of phosphatidylinositol-4,5-bisphosphate soluble phospholipase C from human platelets requires soluble GTP-binding protein. (1988) (0)
- Anti-aging Effects of Retinoids and Mechanisms of Action (2007) (0)
- Expression of CCN Genes and Proteins in Human Skin: Methods and Protocols. (2017) (0)
- Retinoid treatment increases expression of collagen III in 80+ year old individuals (1998) (0)
- Molecular mechanisms of nonablative fractionated laser (2010) (0)
- 296 Recombination efficiency and expression of fibroblast-specific Cre drivers in mouse skin (2020) (0)
- Reduction of CTGF/CCN2 induces cell cycle arrest in primary human adult skin fibroblasts (2011) (0)
- Topical Retinol Restores Type I Collagen Production in Photoaged Forearm Skin within Four Weeks (2016) (0)
- 437 Development and characterization of biomimetic dermal matrices to study the impact of aging on human fibroblast function (2019) (0)
- 619 Prostaglandins contribute to specific ultraviolet irradiation-induced molecular alterations that are critically involved in photoaging process (2017) (0)
- 178 Expression of active matrix metalloproteinase-1 in dermal fibroblasts: A novel mouse model of accelerated human dermal aging (2021) (0)
- Decorin binds to collagen fibrils in human skin and inhibits MMP1 mediated collagen fibril cleavage. (2013) (0)
- Pulsed dye laser treatment of acne vulgaris. Authors' reply (2004) (0)
- Restoration of the basement membrane after wounding: a hallmark of young human skin altered with aging (2017) (0)
- Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin (2013) (0)
- 129 Pervasive immune dysfunction characterizes photoaged skin (2022) (0)
- 1442 Bone marrow-derived fibrocytes contribute to type I collagen production during the early stage of cutaneous wound repair (2018) (0)
- Glucocorticoid and retinoic acid inhibit ultraviolet irradiation induction of cytokine and matrix-degrading metalloproteinase genes through distinct mechanisms in human skin in vivo (1998) (0)
- 268 Enhanced dermal mechanical support rapidly stimulates fibroblasts and stable accumulation of collagen bundles in photoaged human skin (2016) (0)
- 120 Novel mouse model of skin aging: Expression of CCN1 in dermal fibroblasts drives dermal aging and promotes skin cancer development (2017) (0)
- Retinoic Acid 4-Hydroxylase Inducibility and Clinical Response to Isotretinoin in Acne Patients (2011) (0)
- Pulsed dye laser treatment of acne vulgaris [5] (multiple letters) (2004) (0)
- Regulation of TCF-cx Expression in Human Keratinocytes : PKC-Dependent and-Independent Pathways (2004) (0)
- Pulsed Dye Laser Treatment of Acne Vulgaris—Reply (2004) (0)
- Matrix Metalloproteinase-1 Expression in Fibroblasts Accelerates Dermal Aging and Promotes Papilloma Development in Mouse Skin. (2023) (0)
- Increased stress-activated and decreased growth factor-activated map kinase activities lead to collagen deficiency and reduced cell growth in skin of elderly persons (1998) (0)
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What Schools Are Affiliated With Gary J. Fisher?
Gary J. Fisher is affiliated with the following schools:
