Gary Kobinger
Canadian microbiologist
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Biology
Why Is Gary Kobinger Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gary P. Kobinger is a Canadian immunologist and virologist who is currently the director at the Galveston National Laboratory at the University of Texas. He has held previous professorships at Université Laval, the University of Manitoba, and the University of Pennsylvania. Additionally, he was the chief of the Special Pathogens Unit at the National Microbiology Laboratory of the Public Health Agency of Canada in Winnipeg, Manitoba, for eight years. Kobinger is known for his critical role in the development of both an effective Ebola vaccine and treatment. His work focuses on the development and evaluation of new vaccine platforms and immunological treatments against emerging and re-emerging viruses that are dangerous to human health.
Gary Kobinger's Published Works
Published Works
- COVID-19: towards controlling of a pandemic (2020) (1174)
- Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp™ (2014) (919)
- Taxonomy of the order Mononegavirales: update 2016 (2016) (389)
- Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. (2001) (384)
- Ebola virus disease in the Democratic Republic of Congo. (2014) (345)
- Successful Treatment of Ebola Virus–Infected Cynomolgus Macaques with Monoclonal Antibodies (2012) (316)
- Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo (2001) (309)
- Nanozyme-strip for rapid local diagnosis of Ebola. (2015) (248)
- Taxonomy of the order Mononegavirales: update 2019 (2019) (237)
- Taxonomy of the order Mononegavirales: update 2017 (2017) (236)
- A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates (2015) (218)
- Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins. (2002) (207)
- Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial (2019) (202)
- Transmission of Ebola Viruses: What We Know and What We Do Not Know (2015) (191)
- VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain (2015) (188)
- Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus (2016) (185)
- Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine - Preliminary Report. (2017) (183)
- Pre-existing immunity against Ad vectors (2014) (176)
- Human Adaptation of Ebola Virus during the West African Outbreak (2016) (176)
- Structures of protective antibodies reveal sites of vulnerability on Ebola virus (2014) (175)
- Targeted prostaglandin E2 inhibition enhances antiviral immunity through induction of type I interferon and apoptosis in macrophages. (2014) (169)
- Transmission of Ebola virus from pigs to non-human primates (2012) (162)
- A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. (2018) (162)
- Taxonomy of the order Mononegavirales: update 2018 (2018) (155)
- Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens (2008) (151)
- Nasal Delivery of an Adenovirus-Based Vaccine Bypasses Pre-Existing Immunity to the Vaccine Carrier and Improves the Immune Response in Mice (2008) (150)
- Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection (2018) (148)
- PEGylation of a Vesicular Stomatitis Virus G Pseudotyped Lentivirus Vector Prevents Inactivation in Serum (2004) (143)
- Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates (2012) (142)
- Chimpanzee adenovirus vaccine protects against Zaire Ebola virus. (2006) (140)
- Resolution of Primary Severe Acute Respiratory Syndrome-Associated Coronavirus Infection Requires Stat1 (2004) (131)
- mAbs and Ad-Vectored IFN-α Therapy Rescue Ebola-Infected Nonhuman Primates When Administered After the Detection of Viremia and Symptoms (2013) (125)
- Macaque Model for Severe Acute Respiratory Syndrome (2004) (125)
- 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2020) (122)
- Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells. (2003) (122)
- Immunogenicity of novel consensus-based DNA vaccines against avian influenza. (2007) (120)
- Replication, pathogenicity, shedding, and transmission of Zaire ebolavirus in pigs. (2011) (119)
- Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. (2003) (117)
- In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine (2016) (116)
- Intranasal Administration of Alpha Interferon Reduces Seasonal Influenza A Virus Morbidity in Ferrets (2009) (108)
- Ebola viral load at diagnosis associates with patient outcome and outbreak evolution. (2015) (107)
- Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb (2013) (104)
- Oseltamivir-Resistant Pandemic A/H1N1 Virus Is as Virulent as Its Wild-Type Counterpart in Mice and Ferrets (2010) (103)
- Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes. (2002) (101)
- Ebola GP-Specific Monoclonal Antibodies Protect Mice and Guinea Pigs from Lethal Ebola Virus Infection (2012) (98)
- Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae (2012) (97)
- Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza (2013) (94)
- Characterization of host immune responses in Ebola virus infections (2014) (93)
- Molecular Characterization of the Monoclonal Antibodies Composing ZMAb: A Protective Cocktail Against Ebola Virus (2014) (92)
- Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 (2014) (92)
- The Cellular Antiviral Protein APOBEC3G Interacts with HIV-1 Reverse Transcriptase and Inhibits Its Function during Viral Replication (2012) (92)
- Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein. (2007) (88)
- Pandemic Swine-Origin H1N1 Influenza A Virus Isolates Show Heterogeneous Virulence in Macaques (2010) (88)
- Enhanced Protection against Ebola Virus Mediated by an Improved Adenovirus-Based Vaccine (2009) (86)
- DNA vaccination protects mice against Zika virus-induced damage to the testes (2017) (85)
- Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005 (2014) (83)
- Two-mAb cocktail protects macaques against the Makona variant of Ebola virus (2016) (80)
- Blood kinetics of Ebola virus in survivors and nonsurvivors. (2015) (79)
- Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick. (2015) (77)
- Post-exposure therapy of filovirus infections. (2014) (77)
- The multiple roles of sGP in Ebola pathogenesis. (2015) (76)
- Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site (2016) (75)
- Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway (2008) (74)
- Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA (2013) (71)
- Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents (2014) (70)
- Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola. (2013) (69)
- Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein (2005) (68)
- Airway Delivery of an Adenovirus-Based Ebola Virus Vaccine Bypasses Existing Immunity to Homologous Adenovirus in Nonhuman Primates (2013) (67)
- Progression of Ebola Therapeutics During the 2014-2015 Outbreak. (2016) (67)
- Adenovirus Vectors Expressing Hantavirus Proteins Protect Hamsters against Lethal Challenge with Andes Virus (2009) (66)
- Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity (2020) (66)
- Taxonomy of the order Mononegavirales: second update 2018 (2019) (66)
- Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques (2007) (64)
- New filovirus disease classification and nomenclature (2019) (63)
- Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers. (2019) (63)
- Assessment of the Efficacy of Commercially Available and Candidate Vaccines against a Pandemic H1N1 2009 Virus (2010) (62)
- Efficacy of Vesicular Stomatitis Virus-Ebola Virus Postexposure Treatment in Rhesus Macaques Infected With Ebola Virus Makona. (2016) (62)
- Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells. (2003) (61)
- Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection (2011) (61)
- Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae (2013) (60)
- Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease (2016) (60)
- Vesicular stomatitis virus vectors expressing avian influenza H5 HA induce cross-neutralizing antibodies and long-term protection. (2007) (60)
- Adenovirus-based genetic vaccines for biodefense. (2005) (58)
- Recent advances in Ebolavirus vaccine development (2010) (57)
- Long-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonates. (2015) (56)
- Mucosal delivery of adenovirus-based vaccine protects against Ebola virus infection in mice. (2007) (55)
- Efficacy of severe acute respiratory syndrome vaccine based on a nonhuman primate adenovirus in the presence of immunity against human adenovirus. (2006) (55)
- COVID-19: viral–host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection (2020) (54)
- Ebolavirus Evolution: Past and Present (2015) (53)
- Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine. (2021) (53)
- Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names (2014) (53)
- MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus (2017) (53)
- Plant-derived H7 VLP vaccine elicits protective immune response against H7N9 influenza virus in mice and ferrets. (2015) (52)
- Generation of an adenoviral vaccine vector based on simian adenovirus 21. (2006) (51)
- A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus (2016) (50)
- Transduction of human islets with pseudotyped lentiviral vectors. (2004) (49)
- Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection (2016) (48)
- Evaluation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses. (2009) (48)
- A single sublingual dose of an adenovirus-based vaccine protects against lethal Ebola challenge in mice and guinea pigs. (2012) (47)
- Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients. (2016) (47)
- Review of Ebola virus infections in domestic animals. (2013) (46)
- Short-term economic impact of the Zika virus outbreak. (2016) (46)
- Establishment and Characterization of a Lethal Mouse Model for the Angola Strain of Marburg Virus (2014) (45)
- ICTV Virus Taxonomy Profile: Filoviridae (2019) (45)
- 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2021) (44)
- Sulphatase activities are regulated by the interaction of sulphatase‐modifying factor 1 with SUMF2 (2005) (44)
- Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device. (2012) (44)
- Ebola Virus Transmission in Guinea Pigs (2014) (44)
- Personal Protective Equipment for Filovirus Epidemics: A Call for Better Evidence (2015) (43)
- Evaluation of transmission risks associated with in vivo replication of several high containment pathogens in a biosafety level 4 laboratory (2014) (43)
- A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection (2014) (43)
- Impact of systemic or mucosal immunity to adenovirus on Ad-based Ebola virus vaccine efficacy in guinea pigs. (2011) (42)
- Backs against the Wall: Novel and Existing Strategies Used during the 2014-2015 Ebola Virus Outbreak (2015) (42)
- Outbreaks in a Rapidly Changing Central Africa - Lessons from Ebola. (2018) (42)
- Ebola virus disease complicated with viral interstitial pneumonia: a case report (2015) (41)
- Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. (2014) (41)
- Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors (2005) (41)
- Immunopathogenesis of Severe Acute Respiratory Disease in Zaire ebolavirus-Infected Pigs (2013) (41)
- Pause on avian flu transmission research. (2012) (41)
- Antibody therapeutics for Ebola virus disease. (2016) (40)
- Syrian Hamsters as a Small Animal Model for Emerging Infectious Diseases: Advances in Immunologic Methods (2016) (40)
- Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets. (2011) (37)
- Transmission Studies Resume for Avian Flu (2013) (37)
- Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection (2016) (37)
- Ebola Virus Disease, Democratic Republic of the Congo, 2014 (2016) (37)
- Development and Characterization of a Guinea Pig-Adapted Sudan Virus (2015) (36)
- Characterization of the inhibitory effect of an extract of Prunella vulgaris on Ebola virus glycoprotein (GP)-mediated virus entry and infection (2016) (36)
- Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge (2010) (36)
- The endogenous protease inhibitor TIMP-1 mediates protection and recovery from cutaneous photodamage. (2012) (35)
- HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins: sequence requirement for virion incorporation and analysis of antiviral effect (1999) (35)
- Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry. (2018) (35)
- Virulence differences of closely related pandemic 2009 H1N1 isolates correlate with increased inflammatory responses in ferrets. (2012) (35)
- Mutation Signatures and In Silico Docking of Novel SARS-CoV-2 Variants of Concern (2021) (34)
- Vaccine Candidates against Coronavirus Infections. Where Does COVID-19 Stand? (2020) (34)
- Flexibility of Mobile Laboratory Unit in Support of Patient Management During the 2007 Ebola‐Zaire Outbreak in the Democratic Republic of Congo (2012) (34)
- In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model (2018) (34)
- Immune evasion in ebolavirus infections. (2015) (33)
- Intramuscular Adeno-Associated Virus–Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice (2018) (32)
- COVID-19: viral–host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection (2020) (32)
- Pause on Avian Flu Transmission Research (2012) (32)
- Monoclonal Antibodies Combined with Adenovirus-Vectored Interferon Significantly Extend the Treatment Window in Ebola Virus-Infected Guinea Pigs (2013) (32)
- COVID-19 disease—Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study (2020) (31)
- A Single Electroporation Delivery of a DNA Vaccine Containing the Hemagglutinin Gene of Asian H5N1 Avian Influenza Virus Generated a Protective Antibody Response in Chickens against a North American Virus Strain (2013) (31)
- Influenza A vaccines using linear expression cassettes delivered via electroporation afford full protection against challenge in a mouse model. (2012) (30)
- A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model (2010) (30)
- Human fetal trachea-SCID mouse xenografts: efficacy of vesicular stomatitis virus-G pseudotyped lentiviral-mediated gene transfer. (2003) (30)
- Nipah Virus Matrix Protein Influences Fusogenicity and Is Essential for Particle Infectivity and Stability (2015) (30)
- From bench to almost bedside: the long road to a licensed Ebola virus vaccine (2018) (29)
- Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry (2016) (29)
- Effects of IGF-binding protein 5 in dysregulating the shape of human hair. (2011) (29)
- Essential Role of RAB27A in Determining Constitutive Human Skin Color (2012) (29)
- Virion-Targeted Viral Inactivation of Human Immunodeficiency Virus Type 1 by Using Vpr Fusion Proteins (1998) (29)
- Evaluation of Different Strategies for Post-Exposure Treatment of Ebola Virus Infection in Rodents. (2011) (29)
- Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells (2017) (28)
- The emergence of antibody therapies for Ebola. (2015) (27)
- Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe (2021) (27)
- Pentamers Not Found in the Universal Proteome Can Enhance Antigen Specific Immune Responses and Adjuvant Vaccines (2012) (26)
- Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques. (2016) (26)
- Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells. (2007) (26)
- Low incidence of airborne SARS-CoV-2 in acute care hospital rooms with optimized ventilation (2020) (26)
- Complete Genome Sequences of Three Ebola Virus Isolates from the 2014 Outbreak in West Africa (2014) (26)
- Successful Control of Ebola Virus Disease: Analysis of Service Based Data from Rural Sierra Leone (2016) (25)
- Rapid response to an emerging infectious disease – Lessons learned from development of a synthetic DNA vaccine targeting Zika virus (2018) (25)
- The Merits of Malaria Diagnostics during an Ebola Virus Disease Outbreak (2016) (25)
- Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines (2018) (23)
- Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination (2017) (23)
- Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention. (2019) (22)
- The Use of the Anticoagulant Heparin and Corticosteroid Dexamethasone as Prominent Treatments for COVID-19 (2021) (22)
- Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015. (2016) (22)
- Vectored Expression of the Broadly Neutralizing Antibody FI6 in Mouse Airway Provides Partial Protection against a New Avian Influenza A Virus, H7N9 (2013) (22)
- Novel Adeno-associated Viruses Derived From Pig Tissues Transduce Most Major Organs in Mice (2014) (21)
- Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets (2015) (21)
- Viral Hemorrhagic Fevers Other than Ebola and Lassa. (2019) (21)
- Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials. (2016) (19)
- Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules. (2008) (19)
- Environmental Contamination and Persistence of Ebola Virus RNA in an Ebola Treatment Center. (2016) (19)
- Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses (2017) (19)
- Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages. (2011) (18)
- In vitro Susceptibility of Geographically and Temporally Distinct Zika Viruses to Favipiravir and Ribavirin (2017) (18)
- Bioaerosols and Transmission, a Diverse and Growing Community of Practice (2019) (18)
- 2017 Outbreak of Ebola Virus Disease in Northern Democratic Republic of Congo. (2019) (18)
- Development of an HIV vaccine using a vesicular stomatitis virus vector expressing designer HIV-1 envelope glycoproteins to enhance humoral responses (2017) (18)
- Pharmacologically regulated regeneration of functional human pancreatic islets. (2005) (17)
- Adenovirus-Vectored Vaccine Provides Postexposure Protection to Ebola Virus-Infected Nonhuman Primates. (2015) (17)
- Plant-made vaccines and therapeutics (2021) (16)
- Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells. (2019) (16)
- Ebola virus infection induces autoimmunity against dsDNA and HSP60 (2017) (16)
- Co-administration of certain DNA vaccine combinations expressing different H5N1 influenza virus antigens can be beneficial or detrimental to immune protection. (2012) (16)
- Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine. (2017) (16)
- The ongoing evolution of antibody-based treatments for Ebola virus infection. (2017) (16)
- Zika Virus Vaccines: Challenges and Perspectives (2018) (16)
- Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms. (2018) (16)
- The Cellular Impact of the ZIKA Virus on Male Reproductive Tract Immunology and Physiology (2020) (15)
- Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring (2019) (15)
- Development and Characterization of a Sin Nombre Virus Transmission Model in Peromyscus maniculatus (2019) (15)
- Intranasal immunization with an adenovirus vaccine protects guinea pigs from Ebola virus transmission by infected animals. (2015) (15)
- Modeling Ebola Virus Transmission Using Ferrets (2018) (14)
- Characterization of Antiviral Activity of Benzamide Derivative AH0109 against HIV-1 Infection (2013) (14)
- Living with the COVID-19 pandemic: act now with the tools we have (2020) (14)
- More Challenges From Ebola: Infection of the Central Nervous System. (2016) (14)
- Relationship Between Viremia and Specific Organ Damage in Ebola Patients: A Cohort Study (2018) (14)
- Adeno-Associated Virus Serotype 9-Expressed ZMapp in Mice Confers Protection Against Systemic and Airway-Acquired Ebola Virus Infection. (2016) (14)
- Clinical Evaluation of Ebola Virus Disease Therapeutics. (2017) (13)
- Antibody therapy for Ebola (2014) (13)
- NK Cells Accumulate in Infected Tissues and Contribute to Pathogenicity of Ebola Virus in Mice (2019) (13)
- The Makona Variant of Ebola Virus Is Highly Lethal to Immunocompromised Mice and Immunocompetent Ferrets. (2018) (13)
- Recombinant Vectors Based on Porcine Adeno-Associated Viral Serotypes Transduce the Murine and Pig Retina (2013) (13)
- Dual RNA-Seq characterization of host and pathogen gene expression in liver cells infected with Crimean-Congo Hemorrhagic Fever Virus (2020) (12)
- The truth about PHEICs (2019) (12)
- Hypothesis driven development of new adjuvants (2013) (12)
- Optimization of Prime-Boost Vaccination Strategies Against Mouse-Adapted Ebolavirus in a Short-Term Protection Study. (2015) (12)
- Detection of Viral RNA in Tissues following Plasma Clearance from an Ebola Virus Infected Patient (2016) (12)
- Essentials of filoviral load quantification. (2016) (12)
- HIV-1 envelope glycoprotein stimulates viral transcription and increases the infectivity of the progeny virus through the manipulation of cellular machinery (2017) (12)
- A synthetic consensus anti-Spike protein DNA vaccine induces protective immunity against Middle East Respiratory Syndrome Coronavirus in non-human primates (2016) (12)
- Gene transfer in human skin with different pseudotyped HIV-based vectors (2007) (12)
- Diagnosis and management of Ebola samples in the laboratory (2016) (11)
- Quantitative serology assays for determination of antibody responses to Ebola virus glycoprotein and matrix protein in nonhuman primates and humans. (2016) (11)
- Gene Transfer of ZMapp Antibodies Mediated by Recombinant Adeno-Associated Virus Protects Against Ebola Infections. (2017) (11)
- Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time (2017) (11)
- SARS-CoV-2 spillover transmission due to recombination event (2021) (11)
- Hantavirus pulmonary syndrome in Canada: An overview of clinical features, diagnostics, epidemiology and prevention. (2015) (10)
- Ebola and Marburg (2009) (10)
- Construction of a ganciclovir-sensitive lentiviral vector to assess the influence of angiopoietin-3 and soluble Tie2 on glioma growth (2010) (10)
- Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization (2018) (10)
- R88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected Cells (2014) (10)
- Prior infection of chickens with H1N1 avian influenza virus elicits heterologous protection against highly pathogenic H5N2. (2012) (10)
- Hantavirus pulmonary syndrome in Canada: An overview of clinical and diagnostic features, epidemiology and prevention (2015) (10)
- Characterization of a Bivalent Vaccine Capable of Inducing Protection Against Both Ebola and Cross-clade H5N1 Influenza in Mice (2015) (10)
- Detection of Zaire ebolavirus in swine: Assay development and optimization (2018) (9)
- Characterization of Anti-HIV Activity Mediated by HIV-1 Integrase C-terminal Domain Polypeptides Expressed in Susceptible Cells (2010) (9)
- Gut microbiota modulation induced by Zika virus infection in immunocompetent mice (2021) (9)
- Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic (2016) (9)
- Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model (2019) (9)
- Clinical and epidemiological performance of WHO Ebola case definitions: a systematic review and meta-analysis (2020) (9)
- Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses (2019) (9)
- Dendritic Cells/Macrophages-Targeting Feature of Ebola Glycoprotein and its Potential as Immunological Facilitator for Antiviral Vaccine Approach (2019) (9)
- Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice (2019) (9)
- Diagnostic strategies for Ebola virus detection. (2016) (8)
- Pulmonary Involvement during the Ebola Virus Disease (2019) (8)
- Altered microRNA Transcriptome in Cultured Human Liver Cells upon Infection with Ebola Virus (2021) (8)
- Correction for Osterholm et al., Transmission of Ebola Viruses: What We Know and What We Do Not Know (2015) (8)
- Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New Dendritic Cell-Targeting Vaccine Approach against HIV-1 (2021) (8)
- Challenges and perspectives on the use of mobile laboratories during outbreaks and their use for vaccine evaluation (2019) (8)
- Mosquito Species Composition and Abundance in Quebec, Eastern Canada (2020) (7)
- Cross-reactive immunity against SARS-CoV-2 N protein in Central and West Africa precedes the COVID-19 pandemic (2022) (7)
- Taxonomy of the order Mononegavirales: second update 2018 (2019) (7)
- Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models (2021) (7)
- Why has the Ebola outbreak in West Africa been so challenging to control? (2014) (7)
- Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge (2019) (7)
- Vaccines against ‘the other’ Ebolavirus species (2016) (6)
- Baited vaccines: A strategy to mitigate rodent‐borne viral zoonoses in humans (2018) (6)
- Prior Infection of Chickens with H1N1 or H1N2 Avian Influenza Elicits Partial Heterologous Protection against Highly Pathogenic H5N1 (2012) (6)
- Lentiviral vector-mediated gene transfer to human hair follicles. (2009) (6)
- Testing for the presence of SARS‐CoV‐2 RNA in presymptomatic blood donors (2021) (5)
- Contribution of Environment Sample-Based Detection to Ebola Outbreak Management. (2018) (5)
- Vaccine innovation spurred by the long wait for an Ebola virus vaccine. (2020) (5)
- Evaluation of novel HIV vaccine candidates using recombinant vesicular stomatitis virus vector produced in serum-free Vero cell cultures. (2020) (5)
- Consequences of Pathogen Lists: Why Some Diseases May Continue to Plague Us (2019) (5)
- Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2021) (5)
- BoHV-4-based vector delivering Ebola virus surface glycoprotein (2016) (5)
- Viral pathogenesis: Unlocking Ebola persistence (2017) (4)
- How to turn competitors into collaborators (2017) (4)
- Development and characterization of influenza M2 ectodomain and/or hemagglutinin stalk-based dendritic cell-targeting vaccines (2022) (4)
- ZIKA-001: Safety and Immunogenicity of an Engineered DNA Vaccine Against ZIKA virus infection (2017) (4)
- Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus (2020) (4)
- Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters (2022) (4)
- The road to effective and accessible antibody therapies against Ebola virus. (2022) (4)
- 558. Anti-SARS Humoral and Cellular Immunity Evoked by an Adenovirus Vector Expressing Spike Glycoprotein from SARS Coronavirus (2004) (3)
- A novel DNA platform designed for vaccine use with high transgene expression and immunogenicity. (2021) (3)
- Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells (2022) (3)
- Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae (2012) (3)
- Safety and immunogenicity of vesicular stomatitis virus-based vaccines for Ebola virus disease. (2020) (3)
- In Vitro Characterization and In Vivo Effectiveness of Ebola Virus Specific Equine Polyclonal F(ab')2. (2019) (3)
- Computational genomics of Torque teno sus virus and Porcine circovirus in swine samples from Canada. (2020) (3)
- Development and characterization of influenza M2 ectodomain and/or HA stalk-based DC-targeting vaccines for different influenza infections (2021) (2)
- BoHV-4-based vector delivering Ebola virus surface glycoprotein (2016) (2)
- Sulfatase activities are regulated by the interaction of the sulfatase‐modifying factor 1 with SUMF2 (2016) (2)
- Empowerment of Women: Closing the Medical Technologies Gender Gap. (2018) (2)
- Therapeutics Against Filovirus Infection. (2017) (2)
- Modeling Host-Feeding Preference and Molecular Systematics of Mosquitoes in Different Ecological Niches in Canada. (2020) (2)
- Correction: DNA barcodes corroborating identification of mosquito species and multiplex real-time PCR differentiating Culex pipiens complex and Culex torrentium in Iran (2019) (2)
- Rescue of Replication-Competent ZIKV Hidden in Placenta-Derived Mesenchymal Cells Long After the Resolution of the Infection (2019) (2)
- Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA (2013) (2)
- A single immunization with optimized DNA vaccines protects against lethal Ebola virus challenge in mice (VAC8P.1057) (2015) (2)
- Increased mortality in survivors of Ebola virus disease. (2019) (2)
- A computerized data-capture system for animal biosafety level 4 laboratories. (2011) (2)
- Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models (2018) (2)
- Hantavirus Cardiopulmonary Syndrome in Canada (2020) (2)
- A strategy to simultaneously eradicate the natural reservoirs of rabies and Ebola virus (2012) (1)
- A Correction to the Research Article Titled: "Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against (2013) (1)
- Characterization of Ebola Virus Risk to Bedside Providers in an Intensive Care Environment (2021) (1)
- COVID-19 Disease - Temporal Analyses of Complete Blood Count Parameters Over Course of Illness, and Relationship to Patient Demographics and Management Outcomes in Survivors and Non-Survivors: A Longitudinal Descriptive Cohort Study (2020) (1)
- Assessing Antiviral Countermeasures Using Mouse Models of Ebolavirus Infection. (2017) (1)
- Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice (2020) (1)
- Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever. (2018) (1)
- 141. Adenovirus Vaccine to Ebola Virus: Mechanism of Protection and Impact of Pre-Existing Immunity to the Vaccine Carrier (2005) (1)
- E-105 Antibodies against ebola virus: Results of the viral hemorrhagic fever immunotherapeutic consortium (2016) (1)
- 555. Development of a Post-Exposure Treatment for Ebola Virus Infections Based on AAV Vectors and Zmapp Antibody Cocktail (2016) (1)
- Ebola virus is unlikely to become endemic in West Africa (2016) (1)
- Experimental countermeasures against Ebola virus: current progress and an ethical conundrum (2014) (1)
- Human and Livestock Surveillance Revealed the Circulation of Rift Valley Fever Virus in Agnam, Northern Senegal, 2021 (2023) (1)
- SARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants (2023) (1)
- Crimean–Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022 (2022) (1)
- Anti-Ebola GP monoclonal antibodies protect mice and guinea pigs against lethal ebola virus challenge (105.29) (2011) (0)
- 450. A Single Immunization With Optimized DNA Vaccines Protects Against Lethal Ebola Virus Challenge in Mice and Induces Seroconversion in Non-Human Primates Following a DNA Prime–DNA Boost Approach (2015) (0)
- Taxonomy of the order Mononegavirales: update 2018 (2018) (0)
- SARS-COV-2 vaccine development: where are we now? (2020) (0)
- Taxonomy of the order Mononegavirales: update 2016 (2016) (0)
- Ebola virus transmission in guinea pigs 1 2 (2014) (0)
- Small-Molecule Drugs : Repurposing Licensed Therapies for an Alternate Disease (2016) (0)
- A novel intradermal tattoo-based injection device enhances the immunogenicity of plasmid DNA vaccines (2022) (0)
- Is the tide turning around (2014) (0)
- Transient Liver Damage and Hemolysis Are Associated With an Inhibition of Ebola Virus Glycoprotein-Specific Antibody Response and Lymphopenia (2021) (0)
- A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice (2022) (0)
- HIV-1 envelope glycoprotein stimulates viral transcription and increases the infectivity of the progeny virus through the manipulation of cellular machinery (2017) (0)
- Taxonomy of the order Mononegavirales: update 2017 (2017) (0)
- Zika Virus: Methods and Protocols (2020) (0)
- 604. Comparative Analysis of Different Methods for Quantitative Evaluation of Neutralizing Antibody to Ebola Virus in a Biosafety Level 2 or 4 Environment (2006) (0)
- Editorial: Antibody Therapeutics for the Treatment of Filoviral Infection (2022) (0)
- Texas professionals are employing a one health approach to protect the United States against biosecurity threats (2022) (0)
- 1092. Adenovirus-Based Vaccine Prevents Pneumonia in Ferrets Challenged with the SARS Coronavirus (2005) (0)
- Human fetal trachea xenografts recapitulate normal development: implications for fetal gene therapy using pseudotyped AAV vectors (2003) (0)
- Retrospective Studies: Excellent Tools to Complement Surveillance (2013) (0)
- 568. Comparison of Antigen-Specific Immune Responses Elicited by Recombinant Simian Adenoviral Vectors with Deletions in Either E1, or E1/E3, or E1/E4 Regions (2004) (0)
- 436. Developing a Synthetic DNA Vaccine for an Emerging Pathogen - Middle East Respiratory Syndrome (2016) (0)
- Gut microbiota modulation induced by Zika virus infection in immunocompetent mice (2021) (0)
- New filovirus disease classification and nomenclature (2019) (0)
- Overlooking the importance of immunoassays - Authors' reply. (2016) (0)
- 490. Long Term Expression and Biodistribution of HIV Vector Pseudotyped with Deletion Mutant of the Ebola Envelope Glycoprotein Following Instillation in Airway of Nonhuman Primates (2004) (0)
- ADENOVIRUS VECTORS: ADAPTIVE IMMUNITY (2005) (0)
- EBOLA Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates (2012) (0)
- Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae (2013) (0)
- The Contribution of Autoimmunity to Long-Term Sequelae in Viral HemorrhagicFever Survivors (2017) (0)
- 595. Nasal Delivery of Adenovirus Expressing the Ebola Glycoprotein Protects Mice Against Ebola Virus in the Presence of Preexisting Immunity to the Vaccine Carrier (2006) (0)
- Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time (2017) (0)
- 732. A Novel Double-Pseudotyped Viral Vector for Gene Therapy (2004) (0)
- 368. Pseudotyping HIV Vector with the Spike Envelope Protein of SARS-CoV for Studying Viral Tropism, Immunology and Gene Therapy Applications (2004) (0)
- 373. Simian Adenoviral Vector Based-Vaccine Fully Protect Against Ebola Virus Even in the Presence of Pre-Existing Immunity to Human Adenovirus (2004) (0)
- 479. An Optimized DNA Vaccine Formulation Protects Against Lethal Ebola Makona Virus Challenge in Non-Human Primates and Elicits Robust Immune Responses (2016) (0)
- Sphingosine kinases promote Ebola virus infection and can be targeted to inhibit filoviruses, coronaviruses, and arenaviruses using late endocytic trafficking to enter cells (2022) (0)
- Correction to: Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model (2019) (0)
- Cross-reactive immunity against SARS-CoV-2 N protein in Central and West Africa precedes the COVID-19 pandemic (2022) (0)
- Unprecedented short-term in vivo protection in mice with a single immunization of a DNA GP vaccine against heterologous mouse-adapted Ebola virus challenge (2016) (0)
- Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters (2022) (0)
- 139. Priming and Boosting Efficiency of Chimp and Human Adenoviral Vectors in the Setting of Pre-Existing Immunity in Non-Human Primates (2005) (0)
- Usage of vaccines and therapeutics in public health emergencies 1 (2020) (0)
- Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells (2017) (0)
- In vivo generation of collagen specific Tregs with AAV8 suppresses autoimmune responses and arthritis in DBA1 mice through IL10 production (2021) (0)
- Protection and durable humoral and cellular immune responses in cynomolgus macaques following administration of a Zaire Ebola virus (EBOV) GP DNA vaccine delivered by intramuscular or intradermal electroporation (2017) (0)
- Role of Key Infectivity Parameters in the Transmission of Ebola Virus Makona in Macaques (2021) (0)
- Evaluation of mismatched immunity against influenza viruses (2012) (0)
- Structure of neutralizing antibody bound to Zika envelope protein (2016) (0)
- 1016. Novel Chimeric Adenovirus Vaccine Vectors (2004) (0)
- In-Vivo Generation of Antigen-Specific Tregs with AAV8 Suppresses Collagen-Induced Arthritis in DBA1 Mice through IL-10 Production (2021) (0)
- Reply to Reisler et al. (2018) (0)
- Cell Reports Resource In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model (0)
- An Adaptable Platform for in-house Hepatitis C Serology. (2022) (0)
- Chapter 5. Antiviral Strategies for Ebola Virus and Other Filoviruses: Antibodies (2021) (0)
- Hemorrhagic Fevers other than Ebola and Lassa Running title : Viral hemorrhagic fever (2020) (0)
- Targeted PGE2 inhibition enhances anti-viral immunity through induction of Type I interferon in macrophages (P6180) (2013) (0)
- BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine (2023) (0)
- SARS-CoV-2 molecular diagnosis at airports to minimize travel-related COVID-19 spread (2022) (0)
- Prostaglandin E2 Negatively Regulates Immunity To Pulmonary Influenza A Virus Infection (2012) (0)
- Multiple genotypes of Crimean-Congo hemorrhagic fever virus detected in ticks during a one health survey in Agnam, Northeastern Senegal (2022) (0)
- Taxonomy of the order Mononegavirales: update 2019 (2019) (0)
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