Gary Ruvkun | Academic Influence

Gary Ruvkun's AcademicInfluence.com Rankings

Gary Ruvkun

Biology

#288

World Rank

#523

Historical Rank

#168

USA Rank

Genetics

#92

World Rank

#127

Historical Rank

#60

USA Rank

Molecular Biology

#149

World Rank

#153

Historical Rank

#79

USA Rank

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Biology

Gary Ruvkun's Degrees

Bachelors Biology University of California, San Diego

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Why Is Gary Ruvkun Influential?

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According to Wikipedia, Gary Bruce Ruvkun is an American molecular biologist at Massachusetts General Hospital and professor of genetics at Harvard Medical School in Boston. Ruvkun discovered the mechanism by which lin-4, the first microRNA discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing to those targets, and discovered the second miRNA, let-7, and that it is conserved across animal phylogeny, including in humans. These miRNA discoveries revealed a new world of RNA regulation at an unprecedented small size scale, and the mechanism of that regulation. Ruvkun also discovered many features of insulin-like signaling in the regulation of aging and metabolism. He was elected a Member of the American Philosophical Society in 2019.

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Gary Ruvkun's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans (2000) (4911)
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans (1993) (4071)
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA (2000) (2495)
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. (1997) (2174)
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing (2001) (1941)
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans (1997) (1910)
A uniform system for microRNA annotation. (2003) (1825)
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes (2003) (1005)
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity (2003) (940)
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans (1996) (912)
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis (1982) (892)
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. (2000) (773)
A general method for site-directed mutagenesis in prokaryotes (1981) (692)
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. (1998) (691)
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. (1988) (677)
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism (2003) (657)
Regulation of C. elegans life-span by insulinlike signaling in the nervous system. (2000) (631)
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans (2004) (631)
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. (2001) (624)
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant (2000) (599)
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons (2003) (599)
The unc-86 gene product couples cell lineage and cell identity in C. elegans (1990) (586)
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens (2003) (545)
A systematic RNAi screen for longevity genes in C. elegans. (2005) (526)
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis (2013) (512)
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway (2001) (480)
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression (2004) (450)
Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability (2007) (445)
The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. (1998) (431)
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. (1999) (425)
C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. (2009) (402)
Systematic analysis of genes required for synapse structure and function (2005) (399)
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. (2009) (398)
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways (2006) (392)
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans (2008) (381)
daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. (1994) (368)
daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. (2003) (357)
An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. (1998) (353)
The genetics of aging. (1997) (352)
Interspecies homology of nitrogenase genes. (1980) (344)
Control of developmental timing by micrornas and their targets. (2002) (336)
The taxonomy of developmental control in Caenorhabditis elegans. (1998) (336)
Computational and experimental identification of C. elegans microRNAs. (2003) (306)
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses (2012) (302)
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors (1988) (299)
Functional Genomic Analysis of RNA Interference in C. elegans (2005) (291)
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants (2005) (284)
Functional Genomic Analysis of C. elegans Molting (2005) (280)
Regulation of Interneuron Function in the C. elegans Thermoregulatory Pathway by the ttx-3 LIM Homeobox Gene (1997) (266)
Glimpses of a Tiny RNA World (2001) (261)
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability (2013) (259)
Caenorhabditis elegans responses to bacteria from its natural habitats (2016) (256)
Caenorhabditis elegans pathways that surveil and defend mitochondria (2014) (248)
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation. (1996) (246)
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development. (1991) (246)
The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch (1989) (215)
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways* (2001) (214)
A Conserved LIM Protein That Affects Muscular Adherens Junction Integrity and Mechanosensory Function in Caenorhabditis elegans (1999) (213)
Regulation of transcription and cell identity by POU domain proteins (1991) (206)
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. (1997) (203)
Analysis of xbx genes in C. elegans (2005) (202)
Polygenic control of Caenorhabditis elegans fat storage (2006) (200)
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions (2008) (198)
Directed transposon Tn5 mutagenesis and complementation analysis of rhizobium meliloti symbiotic nitrogen fixation genes (1982) (193)
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants. (2007) (191)
RNAi Screening for Fat Regulatory Genes with SRS Microscopy (2010) (181)
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons (1992) (179)
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. (2000) (173)
DAF-16/FOXO employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity (2013) (170)
Molecular biology. Glimpses of a tiny RNA world. (2001) (170)
Caenorhabditis elegans has scores of homoeobox-containing genes (1989) (166)
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa (2015) (163)
A novel repeat domain that is often associated with RING finger and B-box motifs. (1998) (161)
Pathogens (2014) (155)
Biosynthesis of the Caenorhabditis elegans dauer pheromone (2009) (153)
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. (2013) (150)
Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death. (2013) (149)
MicroRNA‐183 family conservation and ciliated neurosensory organ expression (2008) (146)
MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline. (2012) (146)
An image analysis toolbox for high-throughput C. elegans assays (2012) (144)
Alternative olfactory neuron fates are specified by the LIM homeobox gene lim-4. (1999) (144)
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1 (2016) (144)
Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28. (1991) (136)
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. (2004) (135)
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence (2012) (133)
Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. (2003) (132)
PIWI Associated siRNAs and piRNAs Specifically Require the Caenorhabditis elegans HEN1 Ortholog henn-1 (2012) (124)
The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons. (1999) (123)
Regulation of the mec‐3 gene by the C.elegans homeoproteins UNC‐86 and MEC‐3. (1992) (122)
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans (2011) (121)
Miniprimer PCR, a New Lens for Viewing the Microbial World (2007) (118)
The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25 (2006) (114)
A Whole-Genome RNAi Screen for C. elegans miRNA Pathway Genes (2007) (113)
Temporal pattern formation by heterochronic genes. (1997) (112)
Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway* (2002) (112)
Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways (2012) (110)
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. (2000) (106)
Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. (1989) (106)
Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450 (2004) (105)
The perfect storm of tiny RNAs (2008) (104)
A cytoprotective perspective on longevity regulation. (2013) (103)
Expression of the 22 nucleotide let‐7 heterochronic RNA throughout the Metazoa: a role in life history evolution? (2003) (102)
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans (2009) (96)
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7 (2008) (94)
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity (2018) (92)
The Most Conserved Genome Segments for Life Detection on Earth and Other Planets (2008) (90)
The 20 years it took to recognize the importance of tiny RNAs (2004) (88)
Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation. (1994) (88)
Clarifications on miRNA and Cancer (2006) (86)
The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons. (2002) (85)
New motif in PBX genes (1992) (84)
ISRm1: A Rhizobium meliloti insertion sequence that transposes preferentially into nitrogen fixation genes. (1982) (83)
Functional tests of enhancer conservation between distantly related species (2003) (82)
piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. elegans Genes from Misrouting into the RNAi Pathway. (2015) (81)
Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis. (1996) (80)
The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications (2011) (75)
Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes. (1991) (71)
Nematode homeobox cluster (1991) (68)
The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi (2008) (68)
High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA, and siRNA pathways in nematodes (2013) (67)
A soma-to-germline transformation in long-lived C. elegans mutants (2009) (67)
The Caenorhabditis elegans Behavioral Gene unc‐24 Encodes a Novel Bipartite Protein Similar to Both Erythrocyte Band 7.2 (Stomatin) and Nonspecific Lipid Transfer Protein (1996) (66)
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression (2019) (65)
Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes (2012) (64)
The Caenorhabditis elegans homeobox gene cluster. (1993) (60)
Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6. (2001) (59)
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans (2008) (59)
Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling (2013) (59)
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport (2016) (55)
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks (2012) (53)
Two Membrane-Associated Tyrosine Phosphatase Homologs Potentiate C. elegans AKT-1/PKB Signaling (2006) (53)
MUT-14 and SMUT-1 DEAD Box RNA Helicases Have Overlapping Roles in Germline RNAi and Endogenous siRNA Formation (2014) (52)
Microbial Diversity in a Hypersaline Sulfate Lake: A Terrestrial Analog of Ancient Mars (2017) (52)
The C. elegans DAF-2 insulin-like receptor is abundantly expressed in the nervous system and regulated by nutritional status. (2011) (49)
The Caenorhabditis elegans RDE-10/RDE-11 Complex Regulates RNAi by Promoting Secondary siRNA Amplification (2012) (46)
Caenorbabditis elegans has scores of homeobox-containing genes (1989) (45)
Aging, life span, and senescence. (1998) (45)
Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs (2018) (44)
MLT-10 Defines a Family of DUF644 and Proline-rich Repeat Proteins Involved in the Molting Cycle of Caenorhabditis elegans (2010) (43)
Isoform-specific mutations in the Caenorhabditis elegans heterochronic gene lin-14 affect stage-specific patterning. (2001) (41)
Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains. (2007) (40)
The Caenorhabditis elegans ems class homeobox gene ceh-2 is required for M3 pharynx motoneuron function (2003) (39)
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes. (2019) (39)
PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles (2015) (37)
Regulation of C.elegans Life Span by Insulin-Like Signaling (2004) (36)
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity (2019) (35)
Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence (2014) (35)
New insights into siRNA amplification and RNAi (2012) (35)
Detection of broadly expressed neuronal genes in C. elegans. (2007) (33)
Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans (2013) (33)
Gravity Force Transduced by the MEC-4/MEC-10 DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans (2007) (33)
Genetic Regulation of Caenorhabditis elegans Lysosome Related Organelle Function (2013) (31)
Regulation of the C. elegans molt by pqn-47. (2011) (31)
Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. (2006) (31)
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans (2015) (30)
A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans (2006) (30)
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans (2012) (29)
Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway. (2004) (29)
Planetary Protection and Mars Special Regions--A Suggestion for Updating the Definition. (2016) (28)
Small RNA pathway genes identified by patterns of phylogenetic conservation and divergence (2012) (27)
The Caenorhabditis elegans orphan nuclear hormone receptor gene nhr-2 functions in early embryonic development. (1997) (26)
A common theme for LIM homeobox gene function across phylogeny? (1998) (25)
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity (2003) (24)
VP16-activation of the C. elegans neural specification transcription factor UNC-86 suppresses mutations in downstream genes and causes defects in neural migration and axon outgrowth. (1997) (24)
Nucleic Acid Extraction from Synthetic Mars Analog Soils for in situ Life Detection (2017) (23)
Patterning the Nervous System (1997) (23)
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons (2019) (22)
Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans (2014) (22)
Towards in situ sequencing for life detection (2017) (22)
The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes (2018) (22)
Molybdenum cofactor transfer from bacteria to nematode mediates sulfite detoxification (2019) (21)
signals from AGE-1 PI 3 kinase to the DAF-16 transcription factor Akt / PKB transduces insulin receptor-like Caenorhabditis elegans (1998) (21)
Pax genes in Caenorhabditis elegans: a new twist. (1999) (20)
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans (2015) (19)
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility (2020) (19)
Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism (2020) (18)
Germ Cell Genes and Cancer (2010) (18)
Radiation resistance of biological reagents for in situ life detection. (2013) (17)
Advancing the search for extra-terrestrial genomes (2016) (17)
Longevity: Don't hold your breath (2002) (17)
Biological safety in the context of backward planetary protection and Mars Sample Return: conclusions from the Sterilization Working Group (2021) (16)
CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing (2017) (16)
The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA. (2011) (16)
A molecular growth industry (1992) (16)
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells (2019) (15)
Heterochronic genes in development and evolution. (1998) (14)
Nucleic Acid Extraction and Sequencing from Low-Biomass Synthetic Mars Analog Soils for In Situ Life Detection (2017) (13)
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans (2018) (13)
The tiny RNA world. (2003) (12)
Nanopore sequencing at Mars, Europa, and microgravity conditions (2020) (12)
Dual Regulation of the lin-14 Target mRNA by the lin-4 miRNA (2013) (10)
Sequencing nothing: Exploring failure modes of nanopore sensing and implications for life detection. (2018) (10)
Themes from a NASA workshop on gene regulatory processes in development and evolution. (1999) (10)
Acceleration profiles and processing methods for parabolic flight (2017) (9)
Protein-bound molybdenum cofactor is bioavailable and rescues molybdenum cofactor-deficient C. elegans (2020) (9)
Radiation resistance of sequencing chips for in situ life detection. (2013) (9)
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants (2019) (8)
MicroRNAs Visit the ER (2013) (8)
Nanopore sequencing at Mars, Europa, and microgravity conditions (2020) (7)
Corrections and Clarifications (2004) (7)
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes (2019) (7)
Correction: RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans (2009) (7)
Detection of mutations and DNA polymorphisms using whole genome Southern Cross hybridization. (1990) (6)
SETG: An instrument for detection of life on Mars ancestrally related to life on Earth (2011) (6)
Molecular Genetic Analysis of Klebsiella Pneumoniae Nitrogen-fixation (nif) Genes Appendix: Molecular Genetics of Symbiotic Nitrogen Fixation (1981) (6)
Review of the MEPAG Report on Mars Special Regions (2015) (6)
Specific protection of nucleotides in the lac operator from DMS methylation and DNase I nicking by crude bacterial cell extracts. (1982) (5)
Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity (2021) (5)
Human Exploration of Mars at Valles Marineris : The Past , Present , and Future of Life on Mars (2015) (4)
Tiny RNA: Where do we come from? What are we? Where are we going? (2008) (4)
Life detection with the Enceladus Orbiting Sequencer (2013) (4)
Molecular Cloning of Nitrogen Fixation Genes from Rhizobium Meliloti (1981) (4)
Identification of genes in trinucleotide repeat RNA toxicity pathways in C. elegans (2014) (4)
Development of a Nucleic Acid-Based Life Detection Instrument Testbed (2019) (4)
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response (2020) (4)
Cell signalling. A molecular growth industry. (1992) (4)
Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal (2000) (4)
Towards automated high-throughput screening of C. elegans on agar (2010) (4)
Bacterial carotenoids suppress Caenorhabditis elegans surveillance and defense of translational dysfunction (2020) (3)
SETG: Nucleic Acid Extraction and Sequencing for In Situ Life Detection on Mars (2016) (3)
Myeloperoxidase, a Leukocyte-Derived Vascular (2002) (3)
Signaling Pathways that Regulate C. elegans Life Span (2010) (2)
Nucleic Acid Sequencing Under Mars-Like Conditions (2019) (2)
High-resolution mapping reveals a conserved , widespread , dynamic meiotically regulated mRNA methylation program (2014) (2)
moc-6/MOCS2A is necessary for molybdenum cofactor synthesis in C. elegans (2022) (2)
Generation of Temporal and Cell Lineage Asymmetry During C. elegans Development (1992) (1)
elegans Caenorhabditis PI 3 kinase signals that regulate diapause in A PDK 1 homolog is necessary and sufficient to transduce AGE-1 (1999) (1)
mut-16(mg461), an RNAi-defective mutation found in the background of several strains (2009) (1)
Unraveling the secrets of the cell. (2003) (1)
DNA approach to Mars (2004) (1)
miRNA , piRNA , and siRNA pathways in nematodes High-throughput sequencing reveals extraordinary fluidity of Material (2013) (1)
Methods for Extracting Nucleic Acids from Mars Analog Regolith (2016) (1)
How the Common Ancestry Hypothesis Informs the Search for Life on Mars (2010) (1)
Corrigendum: MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability (2014) (1)
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor. (2022) (1)
ACID EXTRACTION AND SEQUENCING FROM LOW-BIOMASS SYNTHETIC MARS ANALOG SOILS (2017) (1)
Genetic analysis of symbiotic nitrogen fixation (1983) (1)
Interspecies homology of nitrogenase genes (recombinant DNA/restriction endonuclease mapping/DNA-DNA hybridization) (2016) (1)
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity (2018) (1)
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways (2022) (1)
Rictor / TORC 2 Regulates Fat Metabolism , Feeding , Growth and Life Span in C . elegans (2017) (0)
PROGRESS AND CHALLENGES FOR LIFE DETECTION VIA NUCLEIC ACID SEQUENCING (2017) (0)
Corrigendum: MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression (2004) (0)
Author Correction: Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans (2022) (0)
Transcriptional control of neural function in C elegans (1998) (0)
UNDERSTANDING HABITABILITY AND BIOSIGNATURE PRESERVATION IN A HYPERSALINE MARS ANALOG ENIVRONMENT : LESSONS FROM SPOTTED LAKE (2017) (0)
Author response: Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity (2019) (0)
In vivo High-Resolution Magic Angle Spinning Proton MR Spectroscopy of Small Whole-Model Organism C. elegans (2010) (0)
Carrier sequencing FastQ data set (2017) (0)
Summary Intercellular signaling of reproductive development by the C . elegans DAF-9 cytochrome P 450 (2004) (0)
Phylogenetic evidence for asparagine to aspartic acid protein editing of N-glycosylated SARS-CoV-2 viral proteins by NGLY1 deglycosylation/deamidation suggests an unusual vaccination strategy (2021) (0)
Nematode homeobox cluster [11] (1991) (0)
ROS-based lethality of C. elegans mitochondrial electron transport mutants grown on E. coli siderophore iron release mutants (2019) (0)
Induction of RNA interference by C. elegans mitochondrial dysfunction via the DRH-1/RIG-I homologue RNA helicase and the EOL-1/RNA decapping enzyme (2020) (0)
Extensive Sequencing Approaches to the Search for Life: Initial Results from the Rio Tinto (2009) (0)
Franklin medal in life science is Presented to (2011) (0)
Protein Sequence Editing of SKN-1 A / Nrf 1 by Peptide : N-Glycanase Controls Proteasome Gene Expression Graphical (2019) (0)
CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing (2018) (0)
Acceleration profiles and processing methods for parabolic flight (2017) (0)
Victor Ambros (1953-) (2020) (0)
Interkingdom competition for Fe(III) revealed by a synthetic lethal interaction between Caenorhabditis elegans mitochondrial electron transport and Escherichia coli siderophore iron release mutations (2019) (0)
Summary Analysis of xbx genes in C . elegans (2005) (0)
ABSTRACT The taxonomy of animal developmental controlgenes revealed by the first complete animal genome sequence (2000) (0)
Informational polymers as unambiguous biomarkers for aqueous-based life (2018) (0)
On Neuromorphic Architectures for Efficient, Robust, and Adaptable Autonomy in Life Detection and Other Deep Space Missions (2017) (0)
Breaking the silence (2004) (0)
Bacterial Resistance of daf-2 Mutants [2] (multiple letters) (2004) (0)
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans (2015) (0)
Regulation of theC. elegansmolt bypqn-47 (2011) (0)
Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF- 16/FoxO activity in C. elegans (2007) (0)
Prevalent, spontaneously occurring mutations at the eri-6/7 locus result in an Eri phenotype (2009) (0)
DEPCOD: a tool to detect and visualize co-evolution of protein domains (2022) (0)

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What Schools Are Affiliated With Gary Ruvkun?

Gary Ruvkun is affiliated with the following schools: