Gary Yellen
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Computer Science
Gary Yellen's Degrees
- PhD Computer Science Stanford University
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(Suggest an Edit or Addition)Gary Yellen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The inward rectification mechanism of the HERG cardiac potassium channel (1996) (766)
- Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel (1991) (653)
- The voltage-gated potassium channels and their relatives (2002) (647)
- Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels. (1990) (567)
- Gated Access to the Pore of a Voltage-Dependent K+ Channel (1997) (491)
- Ionic permeation and blockade in Ca2+-activated K+ channels of bovine chromaffin cells (1984) (484)
- Dynamic Rearrangement of the Outer Mouth of a K+ Channel during Gating (1996) (472)
- The moving parts of voltage-gated ion channels (1998) (467)
- Single Ca2+-activated nonselective cation channels in neuroblastoma (1982) (454)
- Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels. (1991) (435)
- A genetically encoded fluorescent reporter of ATP/ADP ratio (2008) (424)
- Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor. (2011) (399)
- Modulation of K+ current by frequency and external [K+]: A tale of two inactivation mechanisms (1995) (374)
- Blocker protection in the pore of a voltage-gated K+ channel and its structural implications (2000) (362)
- Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor. (2011) (347)
- Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio (2013) (324)
- Visual identification of individual transfected cells for electrophysiology using antibody-coated beads. (1994) (319)
- Properties of single calcium channels in cardiac cell culture (1982) (316)
- The inactivation gate of the Shaker K+ channel behaves like an open-channel blocker (1991) (307)
- An engineered cysteine in the external mouth of a K+ channel allows inactivation to be modulated by metal binding. (1994) (293)
- The internal quaternary ammonium receptor site of Shaker potassium channels (1993) (271)
- Tight Steric Closure at the Intracellular Activation Gate of a Voltage-Gated K+ Channel (2001) (266)
- Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake. (2017) (265)
- Ketogenic Diet Metabolites Reduce Firing in Central Neurons by Opening KATP Channels (2007) (246)
- The ketogenic diet: metabolic influences on brain excitability and epilepsy (2013) (238)
- Use-Dependent Blockers and Exit Rate of the Last Ion from the Multi-Ion Pore of a K+ Channel (1996) (226)
- Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate. (1997) (211)
- Trapping of Organic Blockers by Closing of Voltage-dependent K+ Channels (1997) (210)
- Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges (2004) (208)
- Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step (2014) (206)
- On the Use of Thiol-modifying Agents to Determine Channel Topology (1996) (203)
- The Activation Gate of a Voltage-Gated K+ Channel Can Be Trapped in the Open State by an Intersubunit Metal Bridge (1998) (202)
- Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism (2018) (192)
- Blocker State Dependence and Trapping in Hyperpolarization-Activated Cation Channels (2001) (173)
- A discrete site for general anesthetics on a postsynaptic receptor. (1995) (145)
- Relief of Na+ block of Ca2+-activated K+ channels by external cations (1984) (144)
- Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor. (1991) (137)
- BAD-Dependent Regulation of Fuel Metabolism and KATP Channel Activity Confers Resistance to Epileptic Seizures (2012) (136)
- A perturbation-based method for calculating explicit likelihood of evolutionary co-variance in multiple sequence alignments (2004) (134)
- A novel K+ channel with unique localizations in mammalian brain: Molecular cloning and characterization (1992) (131)
- Permeation in potassium channels: implications for channel structure. (1987) (128)
- Single KATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons (2011) (123)
- Fast and Slow Voltage Sensor Movements in HERG Potassium Channels (2002) (116)
- Inactivation in HCN Channels Results from Reclosure of the Activation Gate Desensitization to Voltage (2004) (114)
- Voltage-Controlled Gating at the Intracellular Entrance to a Hyperpolarization-Activated Cation Channel (2002) (109)
- N-type inactivation and the S4-S5 region of the Shaker K+ channel (1996) (109)
- Ion effects on gating of the Ca(2+)-activated K+ channel correlate with occupancy of the pore. (1992) (100)
- A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging (2014) (72)
- The K+ channel of sarcoplasmic reticulum. A new look at Cs+ block. (1985) (71)
- Ketone bodies, glycolysis, and KATP channels in the mechanism of the ketogenic diet (2008) (69)
- Hepatic NADH reductive stress underlies common variation in metabolic traits (2020) (65)
- Reversal of HCN Channel Voltage Dependence via Bridging of the S4–S5 Linker and Post-S6 (2006) (65)
- Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain. (2012) (62)
- Neurons rely on glucose rather than astrocytic lactate during stimulation (2019) (61)
- Cytosolic NADH-NAD(+) Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging. (2016) (58)
- Distinct Populations of HCN Pacemaker Channels Produce Voltage-dependent and Voltage-independent Currents (2006) (57)
- Two functionally distinct subsites for the binding of internal blockers to the pore of voltage-activated K+ channels. (1996) (56)
- Status of the Intracellular Gate in the Activated-not-open State of Shaker K+ Channels (2005) (55)
- Quantitative two-photon imaging of fluorescent biosensors. (2015) (52)
- The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons (2016) (51)
- Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor. (2014) (50)
- Trapping of Organic Blockers by Closing of Voltage-dependent K 1 Channels Evidence for a Trap Door Mechanism of Activation Gating (1997) (49)
- Movements near the Gate of a Hyperpolarization-activated Cation Channel (2003) (49)
- Cooperative Gating between Single HCN Pacemaker Channels (2006) (48)
- Metabolism Regulates the Spontaneous Firing of Substantia Nigra Pars Reticulata Neurons via KATP and Nonselective Cation Channels (2014) (47)
- Quantitative in vivo imaging of neuronal glucose concentrations with a genetically encoded fluorescence lifetime sensor (2019) (43)
- Conductance mutations of the nicotinic acetylcholine receptor do not act by a simple electrostatic mechanism. (1994) (43)
- Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells (2017) (42)
- Cysteines in the Shaker K+ channel are not essential for channel activity or zinc modulation. (1994) (38)
- Structural changes during HCN channel gating defined by high affinity metal bridges (2012) (36)
- The inward rectifier potassium channel Kir2.1 is expressed in mouse neutrophils from bone marrow and liver. (2015) (34)
- Analysis of Nonstationary Channel Kinetics (1983) (31)
- Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate (2012) (31)
- Sodium channels from human brain RNA expressed in Xenopus oocytes. Basic electrophysiologic characteristics and their modification by diphenylhydantoin. (1989) (29)
- Imaging changes in the cytosolic ATP-to-ADP ratio. (2014) (27)
- BAD and KATP channels regulate neuron excitability and epileptiform activity (2018) (26)
- The bacterial K+ channel structure and its implications for neuronal channels (1999) (26)
- Single Channel Seeks Permeant Ion for Brief but Intimate Relationship (1997) (25)
- Structure and selectivity (1993) (21)
- The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle (2020) (21)
- Covalent modification of engineered cysteines in the nicotinic acetylcholine receptor agonist-binding domain inhibits receptor activation. (1995) (19)
- Channels from genes: The oocyte as an expression system (1984) (18)
- Fluorescent Biosensors for Neuronal Metabolism and the Challenges of Quantitation (2020) (17)
- Metabolic regulation of species-specific developmental rates (2021) (15)
- Keeping K+ completely comfortable (2001) (14)
- Expression of Torpedo nicotinic acetylcholine receptor subunits in yeast is enhanced by use of yeast signal sequences. (1990) (13)
- A high-throughput multiparameter screen for accelerated development and optimization of soluble genetically encoded fluorescent biosensors (2022) (13)
- Alternative mechanism for pathogenesis of an inherited epilepsy by a nicotinic AChR mutation (1996) (13)
- Human cardiac sodium channels expressed in Xenopus oocytes. (1990) (10)
- Live cell imaging of cytosolic NADH/NAD+ ratio in hepatocytes and liver slices. (2018) (10)
- BAD knockout provides metabolic seizure resistance in a genetic model of epilepsy with sudden unexplained death in epilepsy (2018) (10)
- Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated Ki channels ( quaternary ammonium ions / open channel block / balland-chain model ) (8)
- Premonitions of ion channel gating (1998) (8)
- Variants in KCNJ11 and BAD do not predict response to ketogenic dietary therapies for epilepsy (2015) (7)
- Dimers among friends: ion channel regulation by dimerization of tail domains. (2001) (7)
- Neurophotonic tools for microscopic measurements and manipulation: status report (2022) (6)
- The immune system uses ion channels, too (1984) (5)
- Metabolism‐based therapies for epilepsy: new directions for future cures (2021) (4)
- Calcium channels. Structure and selectivity. (1993) (4)
- Dentate Gyrus Granule Cells Channels in Mammalian ATP Analysis of Single K (2015) (3)
- Delivery of AAV for Expression of Fluorescent Biosensors in Juvenile Mouse Hippocampus. (2021) (2)
- Corrigendum: A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging (2016) (1)
- The Na+/K+ pump dominates control of glycolysis in hippocampal dentate granule cells (2022) (1)
- Expression of ATP-Sensitive Potassium (KATP) Channel Subunits in Mammalian Liver (2011) (1)
- Live Cell Imaging of Cytosolic NADH/NAD+ Ratio in Hepatocytes using the Fluorescent Sensor Peredox (2016) (1)
- Outwardly Rectifying Currents in Hepatocytes are Inhibited by 2-APB (2012) (1)
- Editor's evaluation: Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency (2021) (0)
- Faculty Opinions recommendation of Crystal structure and mechanism of a calcium-gated potassium channel. (2002) (0)
- Faculty Opinions recommendation of The open pore conformation of potassium channels. (2002) (0)
- Abstract PR7: Visualizing the dynamic and heterogeneous responses of single cells to inhibitors of the growth factor signaling network (2012) (0)
- Faculty Opinions recommendation of The sodium-activated potassium channel is encoded by a member of the Slo gene family. (2003) (0)
- Hepatic NADH reductive stress underlies common variation in metabolic traits (2020) (0)
- Native Currents in Hepatocytes with Characteristic Properties of Kir2 Channels (2013) (0)
- Faculty Opinions recommendation of The sigma receptor as a ligand-regulated auxiliary potassium channel subunit. (2002) (0)
- GENERAL ANESTHETIC POTENCY IS UNALTERED BY MUTATIONS IN THE M2 (ION CHANNEL) DOMAINS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR THAT MODULATE LOCAL ANESTHETIC POTENCY (1994) (0)
- Decision letter: TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons (2021) (0)
- Author Correction: Metabolic regulation of species-specific developmental rates (2023) (0)
- Managing the Respiratory Burst in Phagocytes Voltage-Gated Proton Channels Find Their Dream Job (2015) (0)
- Faculty Opinions recommendation of Energetic optimization of ion conduction rate by the K+ selectivity filter. (2001) (0)
- Faculty of 1000 evaluation for Ion conduction pore is conserved among potassium channels. (2012) (0)
- Channels + Mice Lacking Kir6.2-Containing ATP-Sensitive K Enhanced Neuronal Damage After Ischemic Insults in (2015) (0)
- Faculty Opinions recommendation of Structural changes in the calcium pump accompanying the dissociation of calcium. (2002) (0)
- Decision letter: Regulation of Eag1 gating by its intracellular domains (2019) (0)
- Faculty Opinions recommendation of Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling. (2002) (0)
- Voltage dependent sodium channels from human cardiac rna expressed in xenopus oocytes (1988) (0)
- Editor's evaluation: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands (2021) (0)
- Author response: The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle (2021) (0)
- Live cell imaging of cytosolic NADH / NAD + ratio in hepatocytes and liver slices 4 5 6 (2017) (0)
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