Gautam Sethi
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Computer Science
Gautam Sethi's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science Stanford University
- Bachelors Computer Science Stanford University
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(Suggest an Edit or Addition)Gautam Sethi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inflammation and cancer: how hot is the link? (2006) (1314)
- The Vascular Endothelium and Human Diseases (2013) (1065)
- Curcumin: Getting Back to the Roots (2005) (683)
- Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. (2007) (576)
- Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors. (2014) (561)
- Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements (2019) (517)
- The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges (2019) (494)
- Thymoquinone: potential cure for inflammatory disorders and cancer. (2012) (456)
- The Role of Resveratrol in Cancer Therapy (2017) (424)
- Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy. (2010) (420)
- TNF: a master switch for inflammation to cancer. (2008) (417)
- Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer (2006) (413)
- Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. (2007) (379)
- Natural products as a gold mine for arthritis treatment. (2007) (378)
- Nuclear Factor-κB Activation: From Bench to Bedside (2008) (369)
- The Multifaceted Role of Curcumin in Cancer Prevention and Treatment (2015) (369)
- Dual role of autophagy in hallmarks of cancer (2018) (367)
- Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance. (2016) (359)
- Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1 (2010) (328)
- Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways (2008) (311)
- Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation. (2007) (308)
- Targeting Nuclear Factor-κB Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis (2008) (297)
- Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). (2007) (296)
- Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-κB Activation and NF-κB-regulated Gene Products Through Modulation of p65 and IκBα Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents* (2006) (293)
- Multifaceted link between cancer and inflammation. (2012) (291)
- Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer. (2011) (288)
- Antioxidant response elements: Discovery, classes, regulation and potential applications (2018) (269)
- From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer (2006) (267)
- β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation. (2011) (266)
- Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma. (2013) (265)
- Ageing and the telomere connection: An intimate relationship with inflammation (2016) (261)
- γ-Tocotrienol Inhibits Nuclear Factor-κB Signaling Pathway through Inhibition of Receptor-interacting Protein and TAK1 Leading to Suppression of Antiapoptotic Gene Products and Potentiation of Apoptosis* (2007) (257)
- Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies. (2013) (256)
- Bioactive natural products in cancer prevention and therapy: Progress and promise. (2016) (247)
- Ursolic Acid Inhibits STAT3 Activation Pathway Leading to Suppression of Proliferation and Chemosensitization of Human Multiple Myeloma Cells (2007) (238)
- Nuclear factor-kappaB activation: from bench to bedside. (2008) (237)
- Targeting transcription factor STAT3 for cancer prevention and therapy. (2016) (221)
- Probiotic Lactobacillus reuteri promotes TNF‐induced apoptosis in human myeloid leukemia‐derived cells by modulation of NF‐κB and MAPK signalling (2008) (219)
- Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT (2012) (217)
- Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer. (2013) (215)
- Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway. (2006) (212)
- Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer (2011) (205)
- Fishery Management Under Multiple Uncertainty (2004) (205)
- Targeting arachidonic acid pathway by natural products for cancer prevention and therapy. (2016) (205)
- Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence. (2014) (204)
- Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway. (2011) (204)
- Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer (2010) (202)
- Targeting autophagy using natural compounds for cancer prevention and therapy (2019) (198)
- Natural product-based nanoformulations for cancer therapy: Opportunities and challenges. (2019) (196)
- Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation (2017) (195)
- Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication (2019) (195)
- From ancient medicine to modern medicine: ayurvedic concepts of health and their role in inflammation and cancer. (2007) (193)
- Capsaicin Is a Novel Blocker of Constitutive and Interleukin-6–Inducible STAT3 Activation (2007) (192)
- The multifaceted role of reactive oxygen species in tumorigenesis (2020) (187)
- Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds. (2016) (179)
- Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer. (2012) (179)
- Do STAT3 inhibitors have potential in the future for cancer therapy? (2017) (176)
- Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS (2013) (171)
- Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue* (2007) (171)
- Analysis of the intricate relationship between chronic inflammation and cancer. (2015) (166)
- Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. (2008) (161)
- Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases (2019) (160)
- Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway (2010) (160)
- Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. (2010) (159)
- Potential pharmacological control of the NF-κB pathway. (2009) (157)
- Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention (2017) (156)
- Embelin, an Inhibitor of X Chromosome-Linked Inhibitor-of-Apoptosis Protein, Blocks Nuclear Factor-κB (NF-κB) Signaling Pathway Leading to Suppression of NF-κB-Regulated Antiapoptotic and Metastatic Gene Products (2007) (153)
- Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines. (2007) (153)
- Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression (2018) (152)
- Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review (2018) (149)
- Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer. (2017) (149)
- Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model (2009) (145)
- NF-κB in cancer therapy (2015) (144)
- Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways (2011) (144)
- Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB–regulated gene products in IFN-α–sensitive and IFN-α–resistant human bladder cancer cells (2007) (144)
- Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model. (2016) (143)
- Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo (2012) (142)
- Targeting cell signaling pathways for drug discovery: An old lock needs a new key (2007) (141)
- Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo (2014) (141)
- Insights into Biological Role of LncRNAs in Epithelial-Mesenchymal Transition (2019) (140)
- Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis? (2021) (138)
- Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP‐1 (2012) (137)
- Isorhamnetin augments the anti-tumor effect of capecitabine through the negative regulation of NF-κB signaling cascade in gastric cancer. (2015) (137)
- Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy (2015) (137)
- Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review (2020) (136)
- γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model (2014) (136)
- A Synthetic Triterpenoid, CDDO-Me, Inhibits IκBα Kinase and Enhances Apoptosis Induced by TNF and Chemotherapeutic Agents through Down-Regulation of Expression of Nuclear Factor κB–Regulated Gene Products in Human Leukemic Cells (2006) (135)
- Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model. (2018) (135)
- Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma (2013) (135)
- Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases. (2016) (134)
- Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products (2014) (134)
- Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo* (2014) (133)
- Triple negative breast cancer in Asia: An insider's view. (2018) (133)
- Back to basics: how natural products can provide the basis for new therapeutics (2007) (132)
- Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. (2008) (131)
- Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? (2015) (131)
- Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice (2011) (131)
- Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells. (2014) (131)
- Honokiol Potentiates Apoptosis, Suppresses Osteoclastogenesis, and Inhibits Invasion through Modulation of Nuclear Factor-κB Activation Pathway (2006) (130)
- Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel (2015) (129)
- Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance (2018) (129)
- Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases. (2014) (128)
- Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 (2013) (127)
- Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer* (2012) (126)
- Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells. (2010) (126)
- Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives (2016) (125)
- Identification of β-Escin as a Novel Inhibitor of Signal Transducer and Activator of Transcription 3/Janus-Activated Kinase 2 Signaling Pathway that Suppresses Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cells (2010) (125)
- Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. (2007) (125)
- γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro‐apoptotic and chemosensitizing agent (2011) (124)
- Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo (2010) (123)
- Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model (2011) (123)
- Expression of NF‐κB parallels COX‐2 expression in oral precancer and cancer: Association with smokeless tobacco (2007) (123)
- Pinitol targets nuclear factor-κB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis (2008) (122)
- Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance (2020) (122)
- Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects. (2015) (122)
- Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis (2018) (121)
- Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products. (2007) (121)
- TNF blockade: an inflammatory issue. (2006) (121)
- First Evidence That γ-Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF-κB Pathway (2012) (120)
- 10 Curcumin — Biological and Medicinal Properties (2006) (119)
- An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases (2019) (119)
- Nuclear factor-kappa B: from clone to clinic. (2007) (119)
- Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer. (2012) (118)
- Morin (3,5,7,2′,4′-Pentahydroxyflavone) Abolishes Nuclear Factor-κB Activation Induced by Various Carcinogens and Inflammatory Stimuli, Leading to Suppression of Nuclear Factor-κB–Regulated Gene Expression and Up-regulation of Apoptosis (2007) (118)
- Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells. (2016) (117)
- Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways (2012) (115)
- Celastrol inhibits proliferation and induces chemosensitization through down‐regulation of NF‐κB and STAT3 regulated gene products in multiple myeloma cells (2011) (115)
- Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4 (2011) (113)
- Role of epigenetics in inflammation-associated diseases. (2013) (113)
- Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. (2006) (111)
- Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway. (2008) (110)
- DEAD-box helicase DP103 defines metastatic potential of human breast cancers. (2014) (109)
- β‐caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP‐1 protein tyrosine phosphatase (2014) (109)
- Targeting TNF for Treatment of Cancer and Autoimmunity. (2009) (107)
- Indirubin Enhances Tumor Necrosis Factor-induced Apoptosis through Modulation of Nuclear Factor-κB Signaling Pathway* (2006) (107)
- Deguelin, an Akt Inhibitor, Suppresses IκBα Kinase Activation Leading to Suppression of NF-κB-Regulated Gene Expression, Potentiation of Apoptosis, and Inhibition of Cellular Invasion1 (2006) (107)
- FBXW7 in Cancer: What Has Been Unraveled Thus Far? (2019) (106)
- Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer (2018) (105)
- Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway (2016) (105)
- Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway. (2015) (104)
- Simvastatin, 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor‐κB ligand through modulation of NF‐κB pathway (2008) (104)
- Mitogen-activated Protein Kinase Kinase-4 Promotes Cell Survival by Decreasing PTEN Expression through an NFκB-dependent Pathway* (2006) (104)
- Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics (2010) (103)
- Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway. (2019) (102)
- Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer (2016) (101)
- Possible use of Punica granatum (Pomegranate) in cancer therapy (2018) (101)
- The Impact of Wind Power Projects on Residential Property Values in the United States: A Multi-Site Hedonic Analysis (2010) (101)
- Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets. (2019) (100)
- Genetic Deletion of NAD(P)H:Quinone Oxidoreductase 1 Abrogates Activation of Nuclear Factor-κB, IκBα Kinase, c-Jun N-terminal Kinase, Akt, p38, and p44/42 Mitogen-activated Protein Kinases and Potentiates Apoptosis* (2006) (99)
- Therapeutic potential of gambogic acid, a caged xanthone, to target cancer. (2018) (98)
- The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies (2018) (98)
- Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα (2007) (97)
- Simvastatin Potentiates TNF-α-Induced Apoptosis through the Down-Regulation of NF-κB-Dependent Antiapoptotic Gene Products: Role of IκBα Kinase and TGF-β-Activated Kinase-11 (2007) (97)
- Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3 (2015) (95)
- Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives (2014) (93)
- The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential. (2020) (93)
- The potential role of boswellic acids in cancer prevention and treatment. (2016) (92)
- Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB. (2012) (92)
- Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells. (2007) (92)
- Butein in health and disease: A comprehensive review. (2017) (92)
- Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review (2015) (92)
- Focus on Formononetin: Anticancer Potential and Molecular Targets (2019) (91)
- Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors (2018) (89)
- A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. (2006) (87)
- Potential of Zerumbone as an Anti-Cancer Agent (2019) (86)
- Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model (2019) (83)
- Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma (2017) (83)
- Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. (2007) (83)
- Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements (2020) (82)
- Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. (2020) (82)
- Piceatannol: A Natural Stilbene for the Prevention and Treatment of Cancer. (2020) (82)
- Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma (2020) (81)
- Potential role of genipin in cancer therapy (2018) (80)
- Role of novel histone modifications in cancer (2015) (80)
- Animal venoms as antimicrobial agents (2017) (79)
- Novel tumor necrosis factor-α induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression. (2018) (78)
- Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma (2016) (78)
- Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells (2014) (76)
- Role of microRNA/Epithelial-to-Mesenchymal Transition Axis in the Metastasis of Bladder Cancer (2020) (75)
- Role of tumor-derived exosomes in cancer metastasis. (2019) (74)
- Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis. (2006) (74)
- Natural Bioactives in Cancer Treatment and Prevention (2015) (74)
- Molecular Mechanisms of Action of Tocotrienols in Cancer: Recent Trends and Advancements (2019) (73)
- A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma (2017) (73)
- Oleuropein induces apoptosis via abrogating NF‐κB activation cascade in estrogen receptor–negative breast cancer cells (2018) (72)
- Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4 (2017) (72)
- Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature. (2020) (72)
- Melioidosis: Clinical impact and public health threat in the tropics (2017) (71)
- Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue. (2007) (71)
- The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy (2020) (70)
- Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers (2015) (70)
- Wanted DEAD/H or Alive: Helicases Winding Up in Cancers (2017) (70)
- The expanding roles of long non-coding RNAs in the regulation of cancer stem cells. (2019) (69)
- Experimental Biology and Medicine (2007) (69)
- The Importance of an Interdisciplinary Research Approach to Inform Wildlife Trade Management in Southeast Asia (2017) (69)
- Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives. (2020) (69)
- Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma (2013) (68)
- Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model (2015) (67)
- Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells (2018) (66)
- Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics. (2016) (66)
- Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma (2018) (65)
- Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha. (2007) (65)
- Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition (2018) (65)
- The Emerging Role of Long Non-Coding RNAs in the Metastasis of Hepatocellular Carcinoma (2019) (64)
- Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade (2018) (63)
- NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance (2018) (63)
- Nuclear Factor-κB: A Holy Grail in Cancer Prevention and Therapy (2006) (62)
- Apigenin: A natural bioactive flavone-type molecule with promising therapeutic function (2018) (61)
- Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention (2013) (61)
- Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma in Vitro and in Vivo* (2014) (61)
- Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma. (2015) (61)
- Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer (2016) (60)
- 6‐Shogaol exerts anti‐proliferative and pro‐apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways (2015) (59)
- Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics (2018) (59)
- Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer (2012) (59)
- Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling. (2018) (59)
- Slow Loris Trade in Vietnam: Exploring Diverse Knowledge and Values (2018) (59)
- Emerging role of exosomes in cancer progression and tumor microenvironment remodeling (2022) (59)
- Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase (2017) (58)
- Nanoparticles Targeting STATs in Cancer Therapy (2019) (58)
- Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades (2013) (58)
- Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: Therapeutic targets for obesity and type 2 diabetes. (2019) (57)
- ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation (2016) (57)
- Potential role of targeted therapies in the treatment of triple-negative breast cancer (2016) (57)
- ‘Lnc’‐ing Wnt in female reproductive cancers: therapeutic potential of long non‐coding RNAs in Wnt signalling (2017) (56)
- Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer. (2021) (56)
- Brassinin Represses Invasive Potential of Lung Carcinoma Cells through Deactivation of PI3K/Akt/mTOR Signaling Cascade (2019) (56)
- Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects. (2021) (56)
- Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol (2018) (55)
- Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer (2020) (54)
- Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. (2006) (53)
- Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma (2018) (52)
- Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kappaB-dependent antiapoptotic gene products: role of IkappaBalpha kinase and TGF-beta-activated kinase-1. (2007) (52)
- Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma (2019) (52)
- Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis (2021) (52)
- Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective (2020) (51)
- β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products (2014) (51)
- Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics. (2017) (51)
- Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma (2018) (51)
- Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesis. (2020) (51)
- Anti-cancer effects of oxymatrine are mediated through multiple molecular mechanism(s) in tumor models. (2019) (50)
- A UNIQUE CDK4/6 INHIBITOR: CURRENT AND FUTURE THERAPEUTIC STRATEGIES OF ABEMACICLIB. (2020) (50)
- A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade (2016) (49)
- TIPE Family of Proteins and Its Implications in Different Chronic Diseases (2018) (49)
- Role of Natural Products in Modulating Histone Deacetylases in Cancer (2019) (49)
- Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model (2015) (48)
- Therapeutic implications of toll‐like receptors in peripheral neuropathic pain (2017) (47)
- Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms (2019) (47)
- Potential Benefits of Edible Berries in the Management of Aerodigestive and Gastrointestinal Tract Cancers: Preclinical and Clinical Evidence (2016) (46)
- Cellular uptake of ginsenosides in Korean white ginseng and red ginseng and their apoptotic activities in human breast cancer cells. (2011) (45)
- Topoisomerase inhibitors: pharmacology and emerging nanoscale delivery systems. (2019) (45)
- Sorcin a Potential Molecular Target for Cancer Therapy (2018) (44)
- Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells. (2019) (44)
- The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells (2019) (43)
- A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia (2020) (43)
- Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn (2017) (43)
- Molecular targets and anti-cancer potential of escin. (2018) (43)
- Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development (2016) (42)
- Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades (2017) (41)
- Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model (2015) (41)
- Wound Healing Activity and Mechanisms of Action of an Antibacterial Protein from the Venom of the Eastern Diamondback Rattlesnake (Crotalus adamanteus) (2014) (41)
- Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells (2019) (41)
- Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model (Molecular Cancer Therapeutics (2009) 8, (959-970)) (2009) (41)
- Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade (2019) (40)
- Novel Medicines and Strategies in Cancer Treatment and Prevention (2014) (40)
- A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation. (2016) (40)
- Mango (Mangifera indica L.): a magnificent plant with cancer preventive and anticancer therapeutic potential (2020) (40)
- Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway. (2020) (39)
- The vital role of ATP citrate lyase in chronic diseases (2019) (39)
- Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review. (2017) (39)
- Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells. (2019) (39)
- Wnt/β-Catenin Signaling as a Driver of Hepatocellular Carcinoma Progression: An Emphasis on Molecular Pathways (2021) (38)
- Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells. (2018) (38)
- A Review on Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Quantification of Oncology Drugs (2018) (37)
- Snake venom phospholipases A(2): a novel tool against bacterial diseases. (2012) (37)
- Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis (2016) (36)
- Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs. (2016) (36)
- Potential application of zerumbone in the prevention and therapy of chronic human diseases (2019) (36)
- Targeting HIF-1-mediated Metastasis for Cancer Therapy. (2020) (36)
- Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors (2015) (36)
- Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives (2012) (35)
- Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ1–42 synthesis by suppressing the activation of STAT3 and cathepsin S (2018) (34)
- Annexin-A1 Regulates MicroRNA-26b* and MicroRNA-562 to Directly Target NF-κB and Angiogenesis in Breast Cancer Cells (2014) (34)
- Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway (2012) (34)
- Corilagin Represses Epithelial to Mesenchymal Transition Process Through Modulating Wnt/β-Catenin Signaling Cascade (2020) (34)
- Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo (2016) (34)
- The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy (2022) (34)
- An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins (2013) (34)
- Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. (2007) (34)
- The Application of Embelin for Cancer Prevention and Therapy † (2018) (33)
- N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway (2018) (33)
- Pharmacological Utilization of Bergamottin, Derived from Grapefruits, in Cancer Prevention and Therapy (2018) (33)
- Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells (2016) (33)
- Casticin inhibits growth and enhances ionizing radiation–induced apoptosis through the suppression of STAT3 signaling cascade (2018) (32)
- Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases (2019) (32)
- Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma. (2021) (32)
- SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation. (2008) (32)
- Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells. (2015) (32)
- The multidimensional role of the Wnt/β‐catenin signaling pathway in human malignancies (2021) (32)
- Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ (2014) (31)
- LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway (2020) (31)
- Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways (2019) (30)
- Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells. (2015) (30)
- Encapsulated human mesenchymal stem cells (eMSCs) as a novel anti-cancer agent targeting breast cancer stem cells: Development of 3D primed therapeutic MSCs. (2019) (30)
- Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells (2016) (30)
- Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy. (2020) (29)
- Celastrol in cancer therapy: Recent developments, challenges and prospects. (2021) (29)
- The Butanol Fraction of Guava (Psidium cattleianum Sabine) Leaf Extract Suppresses MMP-2 and MMP-9 Expression and Activity Through the Suppression of the ERK1/2 MAPK Signaling Pathway (2012) (29)
- Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models (2018) (29)
- Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production. (2016) (29)
- Engineering anti-cancer nanovaccine based on antigen cross-presentation (2019) (29)
- Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM‐p73 mediated apoptosis in oral squamous cell carcinoma (2017) (29)
- Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment (2020) (28)
- Sethi G, Ahn KS, Pandey MK, Aggarwal BB. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB-regulated gene products and TAK1-mediated NF-κB activation. Blood. 2007;109(7):2727-2735. (2013) (27)
- Attenuation of STAT3 Signaling Cascade by Daidzin Can Enhance the Apoptotic Potential of Bortezomib against Multiple Myeloma (2019) (27)
- Abrus agglutinin stimulates BMP‐2‐dependent differentiation through autophagic degradation of β‐catenin in colon cancer stem cells (2018) (27)
- Use of Gallic acid for cancer treatment: Molecular mechanisms and improvement of efficacy by nanoformulations. (2021) (27)
- Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway (2019) (26)
- 2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway (2017) (26)
- NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition (2022) (26)
- Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis (2019) (26)
- The role of hydrogen sulfide in cyclic nucleotide signaling (2017) (26)
- Zyflamend, a Polyherbal Preparation, Inhibits Invasion, Suppresses Osteoclastogenesis, and Potentiates Apoptosis Through Down-Regulation of NF-κ B Activation and NF-κ B–Regulated Gene Products (2007) (26)
- Functional interplay between YY1 and CARM1 promotes oral carcinogenesis (2019) (26)
- Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells (2017) (25)
- Long noncoding RNAs in triple‐negative breast cancer: A new frontier in the regulation of tumorigenesis (2021) (25)
- Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure. (2020) (25)
- Bacteria as a treasure house of secondary metabolites with anticancer potential. (2021) (25)
- Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase (2016) (24)
- In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway. (2004) (23)
- Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential (2019) (23)
- Therapeutic Potential of VEGI/TL1A in Autoimmunity and Cancer. (2009) (23)
- Targeted Deletion of MKK4 Gene Potentiates TNF-Induced Apoptosis through the Down-Regulation of NF-κB Activation and NF-κB-Regulated Antiapoptotic Gene Products1 (2007) (23)
- Involvement of MAP kinase signal transduction pathway in UVB-induced activation of macrophages in vitro. (2003) (23)
- A comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma. (2021) (22)
- Targeting Cancer Stem Cells by Dietary Agents: An Important Therapeutic Strategy against Human Malignancies (2021) (22)
- Circular RNAs in cell cycle regulation: Mechanisms to clinical significance (2021) (22)
- Viperatoxin-II: A novel viper venom protein as an effective bactericidal agent (2015) (22)
- Pomegranate bioactive constituents target multiple oncogenic and oncosuppressive signaling for cancer prevention and intervention. (2021) (21)
- Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. (2007) (21)
- Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model (2019) (21)
- Role of RNF20 in cancer development and progression – a comprehensive review (2018) (21)
- Extracellular vesicles, the cornerstone of next-generation cancer diagnosis? (2021) (20)
- PPARγ Ligand–induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers (2017) (19)
- Nigella Plants – Traditional Uses, Bioactive Phytoconstituents, Preclinical and Clinical Studies (2021) (19)
- Celastrol Alleviates Gamma Irradiation-Induced Damage by Modulating Diverse Inflammatory Mediators (2020) (19)
- RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination (2019) (19)
- Sphingosine 1-Phosphate Receptor 2 Induces Otoprotective Responses to Cisplatin Treatment (2020) (19)
- SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma (2017) (18)
- The Emerging Roles of the HERC Ubiquitin Ligases in Cancer. (2018) (18)
- Circadian Rhythm Disruption and Alzheimer’s Disease: The Dynamics of a Vicious Cycle (2020) (18)
- Role of p38 Mitogen-activated Protein Kinase and Caspases in UV-B–induced Apoptosis of Murine Peritoneal Macrophages¶ (2004) (18)
- A brief update on potential molecular mechanisms underlying antimicrobial and wound-healing potency of snake venom molecules. (2016) (18)
- Non-coding RNAs and macrophage interaction in tumor progression. (2022) (18)
- New approaches in extracellular vesicle engineering for improving the efficacy of anti-cancer therapies. (2021) (17)
- Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kappa B activation and NF-kappa B-regulated gene products. (2007) (17)
- Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF-κB Inflammatory Pathways (2019) (17)
- Designing precision medicine panels for drug refractory cancers targeting cancer STEMNESS traits. (2020) (17)
- Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis (2020) (17)
- Fangchinoline diminishes STAT3 activation by stimulating oxidative stress and targeting SHP-1 protein in multiple myeloma model (2021) (16)
- Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators (2017) (16)
- Bioactive compounds from marine invertebrates as potent anticancer drugs: the possible pharmacophores modulating cell death pathways (2020) (16)
- Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn. (2018) (16)
- Butein and Its Role in Chronic Diseases. (2016) (15)
- Epigenetic Effects of Curcumin in Cancer Prevention (2019) (15)
- Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades. (2021) (15)
- Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy (2021) (15)
- The Role of Curcumin in Modern Medicine (2009) (15)
- Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Regulating the STAT3 Signaling Pathway (2021) (15)
- Deguelin targets multiple oncogenic signaling pathways to combat human malignancies. (2021) (15)
- Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating the TLR4/MyD88 pathway in Sprague Dawley (SD) rats. (2020) (15)
- A facile assay to monitor secretory phospholipase A₂ using 8-anilino-1-naphthalenesulfonic acid. (2014) (14)
- (Nano)platforms in bladder cancer therapy: Challenges and opportunities (2022) (14)
- Anti-Inflammatory and Anticancer Properties of Birch Bark-Derived Betulin: Recent Developments (2021) (13)
- Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action (2015) (13)
- Non-coding RNA-based regulation of inflammation. (2022) (13)
- Mending the bones with natural products. (2007) (13)
- Anti-Inflammatory activity of Angelica keiskei through suppression of mitogen-activated protein kinases and nuclear factor-kappaB activation pathways. (2010) (13)
- Snake Venom Proteins: Development into Antimicrobial and Wound Healing Agents (2014) (13)
- Targeted deletion of MKK4 gene potentiates TNF-induced apoptosis through the down-regulation of NF-kappa B activation and NF-kappa B-regulated antiapoptotic gene products. (2007) (13)
- 3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma (2021) (13)
- Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade (2022) (12)
- Daidzin targets epithelial-to-mesenchymal transition process by attenuating manganese superoxide dismutase expression and PI3K/Akt/mTOR activation in tumor cells. (2022) (12)
- Applying systems thinking to inform studies of wildlife trade in primates (2017) (11)
- Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity. (2015) (11)
- TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation. (2010) (11)
- A Brief Overview of the Antitumoral Actions of Leelamine (2019) (11)
- Role of NF-κB and NF-κB-regulated gene products in chemoresistance and radioresistance (2006) (11)
- Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma. (2017) (10)
- Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions (2022) (10)
- Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy. (2017) (10)
- MicroRNA-196a promotes renal cancer cell migration and invasion by targeting BRAM1 to regulate SMAD and MAPK signaling pathways (2021) (10)
- Clinical translation of patient-derived tumour organoids- bottlenecks and strategies (2022) (10)
- Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics. (2015) (10)
- Mitogen-activated Protein Kinase Kinase-4 Promotes Cell Survival by Decreasing PTEN Expression through (2007) (10)
- Long noncoding RNAs (lncRNAs) in pancreatic cancer progression. (2022) (10)
- Potential of baicalein in the prevention and treatment of cancer: A scientometric analyses based review (2021) (10)
- Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine. (2021) (9)
- Isoimperatorin down-regulates epithelial mesenchymal transition through modulating NF-κB signaling and CXCR4 expression in colorectal and hepatocellular carcinoma cells. (2022) (9)
- Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection (2018) (9)
- Role of histone acetyltransferase inhibitors in cancer therapy. (2021) (9)
- "Emerging role of long non-coding RNA (lncRNA) in human malignancies: A unique opportunity for precision medicine". (2021) (9)
- Plant-based hydrocarbon esters from Tragia involucrata possess antimicrobial and anti-inflammatory activities. (2013) (9)
- Reiterating the Emergence of Noncoding RNAs as Regulators of the Critical Hallmarks of Gall Bladder Cancer (2021) (9)
- Role of protein kinase Cδ in UV-B-induced apoptosis of macrophages in vitro (2005) (9)
- Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1 (2017) (9)
- Putting the BRK on breast cancer: From molecular target to therapeutics (2021) (8)
- Identification of novel peroxisome proliferator-activated receptor-gamma (PPARγ) agonists using molecular modeling method (2014) (8)
- Leelamine Modulates STAT5 Pathway Causing Both Autophagy and Apoptosis in Chronic Myelogenous Leukemia Cells (2022) (8)
- N′‐Alkylaminosulfonyl Analogues of 6‐Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma (2015) (8)
- Activation of c-Jun N-terminal kinase is required for ultraviolet B-induced apoptosis of murine peritoneal macrophages in vitro. (2004) (8)
- A Novel Role of Bergamottin in Attenuating Cancer Associated Cachexia by Diverse Molecular Mechanisms (2021) (8)
- Biological function and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: promises and challenges. (2022) (8)
- Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge? (2021) (8)
- 2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells (2022) (8)
- Bhardwaj A, Sethi G, Vadhan-Raj S, et al. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood. 2007;109(6):2293-2302. (2013) (8)
- Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics (2018) (8)
- Targeting PD-1/PD-L1 axis as new horizon for ovarian cancer therapy. (2022) (7)
- Euphorbiasteroid Abrogates EGFR and Wnt/β-Catenin Signaling in Non-Small-Cell Lung Cancer Cells to Impart Anticancer Activity (2022) (7)
- A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study (2018) (7)
- PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers. (2017) (7)
- WHAT'S FAIR? CONSUMERS AND CLIMATE CHANGE (2000) (7)
- An Overview of the Pharmacological Activities of Scopoletin against Different Chronic Diseases. (2022) (7)
- Curcumin in the treatment of urological cancers: Therapeutic targets, challenges and prospects. (2022) (7)
- Nuclear receptors in oral cancer-emerging players in tumorigenesis. (2022) (7)
- Synthesis and biological evaluation of tetrahydropyridinepyrazoles (‘PFPs’) as inhibitors of STAT3 phosphorylation (2014) (7)
- Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) – experimental validation in human breast and colon cancer (2016) (7)
- Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα (2015) (6)
- Abstract 4711: Targeted inhibition of STAT3 dimerization by garcinol suppresses the growth of human hepatocellular carcinomain vitroandin vivo. (2013) (6)
- Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity (2021) (6)
- Role of p38 Mitogen‐activated Protein Kinase and Caspases in UV‐B‐induced Apoptosis of Murine Peritoneal Macrophages ¶ (2004) (6)
- Corrigendum on "Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer" [Cancer Lett. 363 (1) (2015) 28-36]. (2018) (6)
- Targeted Inhibition of Multiple Proinflammatory Signalling Pathways for the Prevention and Treatment of Multiple Myeloma (2012) (6)
- Annexin-A 1 Regulates MicroRNA-26 b * and MicroRNA-562 to Directly Target NFk B and Angiogenesis in Breast Cancer Cells (2014) (5)
- PAX9 reactivation by inhibiting DNA methyltransferase triggers antitumor effect in oral squamous cell carcinoma. (2022) (5)
- Early Life Irradiation-Induced Hypoplasia and Impairment of Neurogenesis in the Dentate Gyrus and Adult Depression Are Mediated by MicroRNA-34a-5p/T-Cell Intracytoplasmic Antigen-1 Pathway (2021) (5)
- Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers (2021) (5)
- Role of NF-κB in Tumorigenesis (2013) (5)
- Spatiotemporal dynamics of γH2AX in the mouse brain after acute irradiation at different postnatal days with special reference to the dentate gyrus of the hippocampus (2021) (5)
- Nimbolide enhances the antitumor effect of docetaxel via abrogation of the NF-κB signaling pathway in prostate cancer preclinical models. (2022) (5)
- Correction: Role of novel histone modifications in cancer (2018) (5)
- Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma (2014) (5)
- Fangchinoline targets epithelial–mesenchymal transition process by modulating activation of multiple cell‐signaling pathways (2022) (5)
- Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats. (2021) (4)
- The neuroprotective effects of icariin on ageing, various neurological, neuropsychiatric disorders, and brain injury induced by radiation exposure (2022) (4)
- NMR Structure of Carcinoscorpius rotundicauda Thioredoxin-related Protein 16 and Its Role in Regulating Transcription Factor NF-κB Activity* (2012) (4)
- Oroxylin A: A Promising Flavonoid for Prevention and Treatment of Chronic Diseases (2022) (4)
- Role of Celastrol in Chemosensitization of Cancer (2018) (4)
- Natural compounds targeting nuclear receptors for effective cancer therapy. (2022) (4)
- Withanolide modulates the potential crosstalk between apoptosis and autophagy in different colorectal cancer cell lines. (2022) (4)
- Black cardamom (Amomum subulatum Roxb.) fruit extracts exhibit apoptotic activity against lung cancer cells. (2021) (4)
- Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection (2022) (4)
- Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis (2022) (4)
- Caspase-9 and Bax/Bcl-2 Regulation in Ultraviolet B-Induced Apoptosis of Murine Peritoneal Macrophages (2004) (3)
- TNF- a -Induced Mitochondrial Alterations in Human T Cells Requires FADD and Caspase-8 Activation but Not RIP and Caspase-3 Activation (2010) (3)
- Anticancer Effects of Agents Derived from Fruits and Vegetables Against Stomach Cancer (2015) (3)
- The Impact of Wind Power Projects on Residential Property Values in the United States (2009) (3)
- A Comprehensive Review of the Evolution of Insulin Development and Its Delivery Method (2022) (3)
- Gene Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei. (2015) (3)
- Targeting Nuclear Receptors in Lung Cancer—Novel Therapeutic Prospects (2022) (3)
- Reversal of Chemoresistance and Enhancement of Apoptosis by Statins Through Downegulation of the NF- κ B pathway (2009) (3)
- Licorice (Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects (2022) (3)
- Novel amide analogues of quinazoline carboxylate display selective antiproliferative activity and potent EGFR inhibition (2020) (2)
- The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer (2022) (2)
- Possible Involvement of Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway in the Initiation and Progression of Hepatocellular Carcinoma (2014) (2)
- Abstract 4123: Thymoquinone inhibits bone metastasis in a breast cancer mouse model by modulating CXCR4/CXCL12 signaling axis (2016) (2)
- Capsaicin induces G1/S cell cycle arrest leading to apoptosis of multiple myeloma cells through suppression of STAT3 activation and STAT3-regulated gene products. (2006) (2)
- An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins (2013) (2)
- Hypoxia signaling in hepatocellular carcinoma: Challenges and therapeutic opportunities. (2022) (2)
- Thymoquinone inhibits angiogenesis and prostate tumor growth by suppressing MAPK signaling pathways (2008) (2)
- Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c‐met/HGF and its associated downstream signaling pathways (2022) (2)
- Potential Application of Leelamine as a Novel Regulator of Chemokine-Induced Epithelial-to-Mesenchymal Transition in Breast Cancer Cells (2022) (2)
- Unraveling the Potential Role of NEDD4-like E3 Ligases in Cancer (2022) (2)
- Corrigendum to "Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics" [Drug Discov. Today 22 (December (12)) (2017) 1765-1781]. (2019) (2)
- Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products (2013) (2)
- Involvement of Fas/Fas Ligand in Ultraviolet B-Induced Apoptosis of Murine Peritoneal Macrophages (2004) (2)
- First Evidence That g-Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF-kB Pathway (2012) (2)
- Role of Inflammation in Cancer Development (2011) (2)
- Procaine Abrogates the Epithelial-Mesenchymal Transition Process through Modulating c-Met Phosphorylation in Hepatocellular Carcinoma (2022) (2)
- Validation of a LC-MS/MS Method for Quantitative Analysis of MELK Inhibitor OTS167 in Mouse Serum: Application to a Pharmacokinetic Study (2018) (2)
- Synthesis, cytotoxic and heparanase inhibition studies of 5-oxo-1-arylpyrrolidine-3-carboxamides of hydrazides and 4-amino-5-aryl-4H-1,2,4-triazole-3-thiol. (2020) (2)
- Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far? (2023) (2)
- Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer (2016) (2)
- 10 TNF Blockade : An Inflammatory Issue (2005) (2)
- Dual Effects of miR-181b-2-3p/SOX21 Interaction on Microglia and Neural Stem Cells after Gamma Irradiation (2023) (1)
- Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response. (2023) (1)
- Corrigendum to “Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells” [Biochem. Pharmacol. 80 (2010) 1553–1562] (2014) (1)
- Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal (2023) (1)
- eview otential of neem ( Azadirachta indica L . ) for prevention and treatment f oncologic diseases (2016) (1)
- Mechanism of epithelial-mesenchymal transition in cancer and its regulation by natural compounds. (2023) (1)
- Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells (2023) (1)
- WHAT'S FAIR? WORKERS, INVESTORS, AND CLIMATE CHANGE (2000) (1)
- Cancer Therapy : Preclinical First Evidence That g-Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NFk B Pathway (2012) (1)
- Measuring Household Vulnerability: A Fuzzy Approach (2016) (1)
- In response to "Comment on "Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?" Cancer Lett. 2021 May 2; 509 (2021) 63-80". (2021) (1)
- Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo (2014) (1)
- Retraction notice to “Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines” [Biochem. Pharmacol. 73 (2007) 1024–1032]. (2016) (1)
- Chapter 4 Triterpenoids and Sesquiterpenoids for Prostate Cancer Therapy (2016) (1)
- Cancer preventive role of olives and olive oil via modulation of apoptosis and nuclear factor-kappa B activation (2021) (1)
- Role of protein kinase Cdelta in UV-B-induced apoptosis of macrophages in vitro. (2005) (1)
- Abstract C43: Potential role of isorhamnetin to overcome chemoresistance in gastric cancer (2011) (1)
- Targeting signal transducer and activator of transcription (STAT) 3 signaling pathway for prevention and therapy of hepatocellular carcinoma: Evidence from cell based and preclinical studies (2015) (1)
- Repurposing FDA-approved drugs as FXR agonists: a structure based in silico pharmacological study (2022) (1)
- Modulation of diverse oncogenic signaling pathways by oroxylin A: An important strategy for both cancer prevention and treatment. (2022) (1)
- Multifaceted role of gamma-Tocotrienol in cancer therapy (2018) (1)
- Identification of natural peptides as a new class of antimalarial drugs by in silico approaches. (2017) (1)
- Identification of a Novel Wnt Antagonist Based Therapeutic and Diagnostic Target for Alzheimer’s Disease Using a Stem Cell-Derived Model (2023) (1)
- Resveratrol and Its Role in the Management of B-Cell Malignancies—A Recent Update (2023) (1)
- Apoptotic Mechanisms of Quercetin in Liver Cancer: Recent Trends and Advancements (2023) (1)
- multiple myeloma cells B-regulated antiapoptotic and cell survival gene products in human κ chemoresistance through downregulation of STAT3 and nuclear factor- Resveratrol inhibits proliferation, induces apoptosis and overcomes (2013) (1)
- FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites (2023) (1)
- Demystifying the Functional Role of Nuclear Receptors in Esophageal Cancer (2022) (1)
- Tris DBA Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Affecting Multiple Oncogenic Proteins (2020) (0)
- Potential application of Natural agents derived from traditional Chinese Medicine for cancer therapy (2015) (0)
- Effects of Agkistrodon halys Metalloproteinase in vitro and in vivo (2014) (0)
- Targeted inhibition of transcription factor STAT3 for the prevention and treatment of cancer (2016) (0)
- Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma (2013) (0)
- Activated Kinase-1 β Kinase and TGF-α B κ Products : Role of I B-Dependent Antiapoptotic Gene κ NF-Apoptosis through the Down-Regulation of-Induced α Simvastatin Potentiates TNF - (2007) (0)
- PPAR g Ligand – induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers (2017) (0)
- Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells (2023) (0)
- Potential role of diosgenin in prostate cancer therapy (2017) (0)
- Natural Resources for Human Health: A New Interdisciplinary Journal Dedicated to Natural Sciences (2021) (0)
- Molecular mechanisms of cell death (2022) (0)
- Abstract 4611: Novel lysosomotrophic agent inhibits in vivo tumor formation and triggers calcium-dependent cell death in a variety of human cancer cell lines (2014) (0)
- The multifaceted role of reactive oxygen species in tumorigenesis (2020) (0)
- Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives. (2023) (0)
- Mini-review Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer (0)
- Correction to: The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer (2023) (0)
- Celastrol Overcomes Chemoresistance in Vitro and Potentiates the Effect of Bortezomib Against Human Multiple Myeloma in Nude Mice Mode (2012) (0)
- Want of Wnt in Parkinson's disease: Could sFRP disrupt interplay between Nurr1 and Wnt signaling? (2023) (0)
- Abstract 2813: Modulation of Signal Transducer and Activator of Transcription 3 by emodin through the induction of a phosphatase leads to the suppression of HCC growth in orthotopic mouse model (2012) (0)
- Canvassing Prospects of Glyco-Nanovaccines for Developing Cross-Presentation Mediated Anti-Tumor Immunotherapy (2022) (0)
- Clinical translation of patient-derived tumour organoids- bottlenecks and strategies (2022) (0)
- A TELOscopic View of Neuroinflammation (2016) (0)
- Retraction notice to "Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines" [Biochem. Pharmacol. 73 (2007) 1024-1032]. (2016) (0)
- Rational Design of a Therapeutic Program for Multiple Myeloma Using a Strategy of Drug Repurposing and Combination Therapy (2012) (0)
- Effect of Diosgenin on STAT3 signaling cascade in hepatocellular carcinoma (2009) (0)
- RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination (2019) (0)
- β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products (2013) (0)
- Oncogenic transcription factor STAT3 as a target for cancer prevention and therapy (2017) (0)
- Abstract 3790: Artesunate inhibits multiple proinflammatory transcription factors leading to the suppression of growth and induction of apoptosis in prostate cancer cells (2014) (0)
- De Novo Design of Imidazopyridine-Tethered Pyrazolines That Target Phosphorylation of STAT3 in Human Breast Cancer Cells (2023) (0)
- Abstract 1240: Identification of molecular targets of Tris DBA [Tris(dibenzylideneacetone)dipalladium(0)] for cancer therapy (2019) (0)
- Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo (2017) (0)
- Anti-Proliferative and Pro-Apoptotic Effects of Bioactive Constituents Derived from Fruits and Vegetables Against Colorectal Cancer (2015) (0)
- Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers (2021) (0)
- Brassinin Induces Apoptosis, Autophagy, and Paraptosis via MAPK Signaling Pathway Activation in Chronic Myelogenous Leukemia Cells (2023) (0)
- Long noncoding RNAs induced control of ferroptosis: Implications in cancer progression and treatment. (2023) (0)
- Mouse Serum : Application to a Pharmacokinetic Study (2018) (0)
- Inaugural editorial for Gene & Protein in Disease (2022) (0)
- Role of NF-κB Activation in Multiple Myeloma and Other Hematological Malignancies (2020) (0)
- Activation of PPARγ signaling cascade by IH (2012) (0)
- The Role of Natural Flavonoids as Telomerase Inhibitors in Suppressing Cancer Growth (2023) (0)
- Targeting Autophagy Using Long Non-Coding RNAs (LncRNAs): New Landscapes in the Arena of Cancer Therapeutics (2023) (0)
- Burkholderia pseudomallei Toxins and Clinical Implications (2016) (0)
- MedChemComm Broadening the field of opportunity for medicinal chemists (0)
- Gossypol and Its Natural Derivatives: Multitargeted Phytochemicals as Potential Drug Candidates for Oncologic Diseases (2022) (0)
- Targeting STAT3 signaling pathway in cancer: Pharmacological inhibitors and clinical implications (2016) (0)
- Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells (2023) (0)
- Noncoding RNAs in Cancer Therapy (2022) (0)
- STAT3 as a molecular target for prostate cancer prevention and therapy (2017) (0)
- NF-κB as a Potential Molecular Target for Therapy of Gastrointestinal Cancers (2017) (0)
- Correction: Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells (2019) (0)
- Abstract 677: Possible role of nimbolide in prevention and therapy of prostate cancer (2015) (0)
- An efficient human stem cells derived cardiotoxicity testing platform for testing oncotherapeutic analogues of quercetin and cinnamic acid (2022) (0)
- Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer. (2013) (0)
- Abstract 1978: Isorhamnetin modulates PPARδ activation pathway leading to the suppression of proliferation, invasion and induction of apoptosis in gastric cancer (2012) (0)
- Loganic acid regulates the transition between epithelial and mesenchymal-like phenotypes by alleviating MnSOD expression in hepatocellular carcinoma cells. (2023) (0)
- A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade (2016) (0)
- BRK”ing” Down All We Know About PTK6 in Breast Cancer (2018) (0)
- Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives (2014) (0)
- NF-κB in cancer therapy (2015) (0)
- ACHP Targets the STAT3 (2020) (0)
- Modulation of oncogenic transcription factors for cancer therapy (2018) (0)
- Potential role of pharmacological STAT3 inhibitors for cancer therapy (2016) (0)
- The vital role of ATP citrate lyase in chronic diseases (2019) (0)
- STAT3 as a molecular target for cancer prevention and therapy (2017) (0)
- Cell-targeted inhibition of constitutively activated NF-κB using IkBα/scFvMEL fusion construct radiosensitizes human melanoma cells. (2006) (0)
- Samy, Ramar Perumal and Stiles, Bradley G. and Chinnathambi, Arunachalam and Zayed, M. E. and Alharbi, Sulaiman Ali and Franco, (2018) (0)
- Role of nuclear factor-κB pathway in gastrointestinal inflammation and cancer (2012) (0)
- Polymeric Hydrogels for Controlled Release of Black Tea and Coffee Extracts for Topical Applications (2021) (0)
- Protective effects of ursolic acid against gamma irradiation induced injury through NF-κB pathway (2017) (0)
- Recent Advancement of Medical Patch for Transdermal Drug Delivery (2023) (0)
- Abrogation of STAT3 activation cascade by Ginkgolide C mitigates tumorigenesis in lung cancer preclinical model (2020) (0)
- PO-462 Investigating the potential anti-cancer properties of a novel src family kinase inhibitor in triple negative breast cancer (2018) (0)
- Colon cancer chemoresistance and chemosensitization (2018) (0)
- Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases (2019) (0)
- Teaser Vitamin E is a lipid-soluble , radical buster existing in two different isoforms : tocotrienols and tocopherols (2017) (0)
- Identification of (cid:1) -Escin as a Novel Inhibitor of Signal Transducer and Activator of Transcription 3/Janus-Activated Kinase 2 Signaling Pathway that Suppresses Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cells (2010) (0)
- Curcumin as a Potential Therapeutic for Alzheimer’s Disease: A Multi-targeted Approach (2019) (0)
- Featuring the special issue guest editor. (2021) (0)
- Recent Development of Nanomaterials for Transdermal Drug Delivery (2023) (0)
- Purification and Biological Evaluation of Some Bioactive Metabolomics as Antimicrobial Agent (2013) (0)
- Abstract 2104: In vitro validation of rationally designed therapeutic based on drug repositioning and combinations. (2013) (0)
- Roles and responsibilities (2018) (0)
- List of contributors (2021) (0)
- Response to Industrial Wind Action Group Critiques (2009) (0)
- Issue Information‐ToC (2018) (0)
- The Final Dataset Consists of 7,459 Valid Residential Transactions Occurring between Pre Announcement Post Announcement Pre Construction 1st Year after Construction 2nd Year after Construction 2ϩ Years after Construction Total (2011) (0)
- Multiple Uncertainty (2004) (0)
- Interdisciplinary and Topical in the Science Classroom: Regulating Carbon Emissions to Mitigate Climate Change (2018) (0)
- Issue Information‐ToC (2021) (0)
- Cells : Delineation of a Novel Pathway B in Cancer κ Constitutive Activation of Nuclear Factor-Overexpression of Tissue Transglutaminase Leads to Updated (2006) (0)
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What Schools Are Affiliated With Gautam Sethi?
Gautam Sethi is affiliated with the following schools:
